No definition available.
Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
AB1_HIV_INFECT_PARASITES
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
103 |
4. Check minimum number of eventsNone |
103 |
5. Include endpointsNone |
103 |
6. Filter based on genotype QC (FinnGen only) |
80 |
Control definitions (FinnGen only)
- Control exclude
- AB1_HIV
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
based on the number of shared cases.
Similar with more cases:
- Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases, including avohilmo
- Human immunodeficiency virus [HIV] disease
- Human immunodeficiency virus [HIV] disease, including avohilmo
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 721 | 224 | 457 |
| Only index persons | 565 | 193 | 372 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 43.20 | 40.28 | 45.11 |
| Only index persons | 43.37 | 39.02 | 45.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 80 | 18 | 62 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | 47.74 | 54.40 | 45.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 94
- Matched controls
- 940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
+∞
81.5
66
*
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
+∞
69.7
58
*
WW200
NOMESCO Finland
Immunization
214.6
67.6
64
9
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
31.2
61.9
50
33
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
+∞
54.6
47
*
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
+∞
36.9
33
*
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
12.9
24.8
28
30
B20.9
ICD-10 Finland
HIV disease resulting in unspecified infectious or parasitic disease
+∞
21.7
20
*
Z3231
NOMESCO Finland
Registered nurse
7.0
20.1
57
170
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
18.3
17
*
Z25.1
ICD-10 Finland
Need for immunization against influenza
19.4
17.1
26
18
B20.0
ICD-10 Finland
HIV disease resulting in mycobacterial infection
+∞
13.9
13
*
Z2221
NOMESCO Finland
Medical doctor
5.0
13.8
49
167
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.3
12.8
68
312
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.9
12.3
22
40
B20.1
ICD-10 Finland
HIV disease resulting in other bacterial infections
+∞
11.7
11
*
B20.3
ICD-10 Finland
HIV disease resulting in other viral infections
+∞
11.7
11
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
40.6
11.6
14
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.5
11.6
43
148
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
32.4
11.1
14
5
J05AB11
ATC
valaciclovir; oral
4.9
9.8
26
68
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
9.5
9
*
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
8.5
8
*
B20.7
ICD-10 Finland
HIV disease resulting in multiple infections
+∞
8.5
8
*
R4110
NOMESCO Finland
Physiotherapy
3.5
7.9
42
178
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.3
7.4
22
62
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.3
7.4
22
62
JN4BD
NOMESCO Finland
Extensive body CT
4.9
7.4
18
43
B20.4
ICD-10 Finland
HIV disease resulting in candidiasis
+∞
7.4
7
*
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
4.0
6.8
22
66
XF400
NOMESCO Finland
ECG with 12 standard connections
3.6
6.5
26
90
WYA30, ,
SPAT
74.7
6.5
7
*
B20.2
ICD-10 Finland
HIV disease resulting in cytomegaloviral disease
+∞
6.3
6
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.9
6.3
15
25
N06AB04
ATC
citalopram; systemic
3.4
6.2
28
105
Z2446
NOMESCO Finland
Social worker
5.7
6.1
17
35
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
9.0
6.0
12
15
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
5
1110.96
99.02
20.1
1.2
11730.35
—
u/ml
—
54
0
53
68
16.58
43.60
2.7
2.7
30.92
28.95
u/l
0.23
53
56
29
39
10.31
21.69
3.6
2.6
—
—
—
0
0
28
38
10.07
20.74
3.5
2.4
—
—
—
0
0
77
315
8.99
19.09
18.4
3.7
31.55
33.19
u/l
0.32
77
301
75
337
7.06
15.57
7.1
5.9
37.80
36.21
g/l
1.46
75
324
83
433
8.83
13.87
6.2
3.3
0.00
0.00
estimate
-0.00
11
85
83
437
8.69
13.60
6.2
3.4
0.00
0.00
estimate
-0.00
12
86
36
96
5.46
13.59
3.7
2.3
—
—
—
0
0
34
88
5.49
13.24
3.4
2.2
—
—
—
0
0
83
446
8.36
13.02
6.2
3.4
0.00
0.00
estimate
—
10
77
13
5
29.79
10.12
1.1
1.0
—
—
—
0
0
51
225
3.77
9.29
5.6
3.2
0.13
0.38
e6/l
1.34
34
164
81
492
5.67
9.20
10.7
5.3
6.35
6.77
mmol/l
1.31
81
471
13
8
18.57
8.84
4.5
3.4
—
—
—
0
0
35
124
3.90
8.74
5.0
3.0
0.20
0.96
e6/l
1.46
15
54
8
0
+∞
8.45
5.1
0.0
—
—
—
0
0
20
33
7.40
8.43
1.3
1.5
131.20
336.69
miu/ml
—
5
17
18
40
5.33
8.05
1.5
1.6
—
—
—
0
0
36
137
3.64
8.00
4.9
2.9
0.25
0.83
e6/l
1.37
16
67
15
20
8.70
7.24
1.1
1.4
—
—
—
0
0
21
58
4.37
7.23
3.5
2.8
66.50
63.29
ml/min/173m2
—
10
24
15
23
7.54
6.66
2.7
2.3
0.75
4.56
index
—
8
9
10
8
13.79
6.24
4.4
3.3
—
—
—
0
0
15
27
6.40
5.99
1.3
1.3
1.68
0.14
iu/ml
—
6
5
16
33
5.62
5.76
1.3
1.2
—
—
—
0
0
11
14
8.73
5.52
2.8
1.3
—
—
—
0
0
14
27
5.90
5.33
2.3
1.5
—
—
—
0
0
15
32
5.37
5.27
4.1
2.8
—
—
—
0
0
9
9
10.90
5.15
1.4
1.8
—
—
—
0
0
11
22
5.51
4.15
3.8
1.4
—
—
—
0
0
14
43
3.65
4.09
2.5
2.7
23.71
24.76
mmol/l
0.66
14
43
59
389
2.39
3.98
9.5
8.3
1.20
1.20
mmol/l
0.39
49
352
15
50
3.38
3.89
2.5
4.6
75.53
76.15
ng/l
0.02
15
45
6
6
10.56
3.55
2.2
1.3
1.17
0.50
index
—
6
6
6
6
10.56
3.55
1.5
1.5
620.17
509.50
u/ml
—
6
6
16
59
3.06
3.53
1.4
1.6
—
—
—
0
0
18
73
2.81
3.37
2.3
2.9
—
—
—
0
0
27
136
2.38
3.28
2.0
2.0
—
—
—
0
0
7
12
6.20
3.08
1.1
1.1
—
—
—
0
0
22
105
2.43
2.98
2.2
2.0
—
—
—
0
0
22
109
2.33
2.74
2.2
1.9
—
—
—
0
0
9
26
3.71
2.56
1.6
2.2
3.93
3.55
g/l
—
9
26
7
16
4.63
2.52
1.4
1.9
—
—
—
0
0
7
16
4.63
2.52
1.4
1.9
—
—
—
0
0
13
53
2.69
2.40
24.2
10.6
24.69
24.69
mmol/l
0.00
13
53
6
13
4.85
2.31
1.2
1.2
—
—
—
0
0
8
24
3.54
2.23
1.0
1.1
—
1.88
—
0
5
89
797
3.19
2.10
30.9
14.2
83.88
85.70
ml/min/173m2
0.41
84
741
8
26
3.26
2.06
1.0
2.2
241.88
178.38
%
—
8
26
20
328
0.50
1.97
2.4
3.6
16.33
48.83
ng/l
—
9
227
7
22
3.35
1.92
1.1
1.2
—
—
—
0
0
6
17
3.69
1.87
1.2
1.2
—
—
—
0
0
29
185
1.82
1.80
2.4
2.4
—
—
—
0
0
8
30
2.82
1.77
1.1
1.8
92.13
92.13
%
—
8
30
89
813
2.78
1.65
26.0
15.1
22.92
24.32
mg/l
0.20
80
661
6
20
3.13
1.61
1.2
1.4
—
—
—
0
0
13
67
2.09
1.46
1.9
1.5
—
—
—
0
0
37
270
1.61
1.38
2.4
2.2
114.89
201.20
u/l
2.00
37
263
43
330
1.56
1.28
2.0
2.0
94.51
91.24
pmol/l
0.24
25
162
25
168
1.66
1.27
4.4
3.4
27.94
226.06
ng/l
1.80
18
137
20
128
1.71
1.21
17.9
7.8
105.30
104.22
mmol/l
0.64
20
128
5
21
2.46
1.10
1.2
1.8
—
—
—
0
0
46
369
1.48
1.06
3.0
2.8
—
—
estimate
—
0
0
5
22
2.34
1.04
1.4
1.4
—
—
—
0
0
0
28
0.00
0.99
0.0
1.6
—
—
—
0
0
6
30
2.07
0.88
1.3
1.5
2.06
1.73
mg/l
—
6
23
28
359
0.69
0.87
3.8
4.0
21.73
21.52
%
—
7
137
25
324
0.69
0.81
5.9
3.2
0.18
0.00
estimate
0.47
11
74
11
70
1.65
0.68
1.9
2.5
0.20
0.23
g/l
0.42
11
62
5
28
1.83
0.67
1.2
3.0
0.00
0.00
g/l
—
5
28
19
142
1.42
0.60
2.4
2.4
14.24
13.96
umol/l
0.05
19
132
19
147
1.37
0.50
1.4
1.5
—
—
—
0
0
23
282
0.76
0.50
2.8
2.8
0.51
0.72
ug/l
1.20
14
141
62
566
1.28
0.48
3.6
3.0
—
—
—
0
0
20
249
0.75
0.48
7.0
2.7
0.00
0.01
estimate
0.49
11
69
14
104
1.41
0.46
1.8
1.6
913.64
1169.23
nmol/l
0.50
14
80
5
32
1.59
0.43
1.0
1.2
—
—
—
0
0
8
58
1.41
0.43
38.1
12.2
1.06
1.69
%
—
8
58
5
33
1.54
0.42
1.0
1.4
—
—
—
0
0
31
265
1.25
0.41
4.9
4.3
14.22
9.15
mg/mmol
0.30
22
180
62
660
0.82
0.34
5.2
3.5
65.04
54.10
u/l
0.27
57
637
7
55
1.29
0.31
43.4
12.7
0.57
0.62
%
—
7
55
15
124
1.25
0.26
2.7
2.3
28.60
24.15
%
0.27
15
117
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
1.13
—
0
6
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
3.9
—
1718.44
—
0
14
11
90
1.25
0.20
1.6
2.4
325.55
393.71
nmol/l
0.64
11
82
20
217
0.90
0.10
5.1
3.6
0.00
0.00
estimate
-0.00
11
80
15
161
0.92
0.05
2.3
2.5
16.47
15.38
nmol/l
0.22
15
155
7
77
0.90
0.00
2.4
4.2
2.27
65.05
ug/l
—
7
61
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
57.85
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.4
—
1.11
—
0
9
0
6
0.00
-0.00
0.0
6.0
—
10.48
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
6.45
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
21.58
—
0
6
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
1.0
—
140.40
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
109.86
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
313.83
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
3.21
—
0
7
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
-0.00
0.0
2.8
—
101.50
—
0
6
0
6
0.00
-0.00
0.0
3.0
—
214.67
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
117.33
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
199.34
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
13.43
—
0
7
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.0
—
4.64
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
1.14
—
0
7
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
8.38
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
10.40
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HIV_INFECT_PARASITES and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HIV_INFECT_PARASITES | 4.062 [2.74, 6.01] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.052 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 367 males with AB1_HIV_INFECT_PARASITES died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HIV_INFECT_PARASITES.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.694% |
| 5 | No data | 4.927% |
| 10 | No data | 12.343% |
| 15 | No data | 22.69% |
| 20 | No data | 36.882% |
Relationships between endpoints
↥Index endpoint: AB1_HIV_INFECT_PARASITES – Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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