Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases, including avohilmo

AB1_HIV_INFECT_PARASITES_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 B20
  • Hospital discharge: ICD-10 B20
  • Cause of death: ICD-10 B20

3 out of 7 registries used, show all original rules.

119

4. Check minimum number of events

None

119

5. Include endpoints

None

119

6. Filter based on genotype QC (FinnGen only)

93

Control definitions (FinnGen only)

Control exclude
AB1_HIV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 93 24 69
Unadjusted period prevalence (%) 0.03 0.01 0.03
Median age at first event (years) 49.20 57.49 46.32

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
110
Matched controls
1100
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
WW200
NOMESCO Finland
Immunization
158.7
133.8
70
12
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
+∞
89.0
73
*
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
+∞
70.6
60
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
28.5
68.3
57
40
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
+∞
54.9
48
*
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
+∞
36.5
33
*
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
12.1
26.0
30
33
B20.9
ICD-10 Finland
HIV disease resulting in unspecified infectious or parasitic disease
+∞
23.8
22
*
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
22.7
21
*
Z3231
NOMESCO Finland
Registered nurse
6.4
21.4
64
197
Z25.1
ICD-10 Finland
Need for immunization against influenza
20.1
19.9
30
20
Z2221
NOMESCO Finland
Medical doctor
5.2
16.8
59
200
B20.4
ICD-10 Finland
HIV disease resulting in candidiasis
+∞
16.0
15
*
B20.1
ICD-10 Finland
HIV disease resulting in other bacterial infections
+∞
14.9
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.0
14.2
78
362
B20.0
ICD-10 Finland
HIV disease resulting in mycobacterial infection
+∞
13.8
13
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.3
12.7
49
172
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
11.7
11
*
B20.3
ICD-10 Finland
HIV disease resulting in other viral infections
+∞
11.7
11
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
28.6
11.5
15
6
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.6
11.4
25
55
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
24.5
11.0
15
7
Z2446
NOMESCO Finland
Social worker
5.7
9.7
20
41
R4110
NOMESCO Finland
Physiotherapy
3.5
9.4
50
211
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.6
9.3
26
70
J05AB11
ATC
valaciclovir; oral
4.4
9.3
28
80
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
5.4
8.7
19
41
B20.7
ICD-10 Finland
HIV disease resulting in multiple infections
+∞
8.4
8
*
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
4.8
8.2
21
52
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.9
7.8
19
45
N06AB04
ATC
citalopram; systemic
3.5
7.8
34
125
Z3226
NOMESCO Finland
Physiotherapist
3.4
7.2
32
118
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
7.2
23
68
WYA30, ,
SPAT
42.8
6.8
8
*
WX110, ,
SPAT
4.6
6.6
17
42
XF400
NOMESCO Finland
ECG with 12 standard connections
3.4
6.6
29
106
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
74.0
6.5
7
*
OAB43, ,
SPAT
0.2
6.3
9
317
TLC02
NOMESCO Finland
Simple extraction of IUD
28.5
6.3
8
*
B20.2
ICD-10 Finland
HIV disease resulting in cytomegaloviral disease
+∞
6.3
6
*
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
+∞
6.3
6
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.9
6.2
20
59
A63.0
ICD-10 Finland
Anogenital (venereal) warts
8.0
6.1
13
18

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
82
7
446.37
93.09
4.2
1.3
28.13
42.29
%
—
82
7
76
85
26.69
71.09
5.2
1.4
—
—
—
0
0
73
78
25.85
70.03
3.4
2.0
—
—
—
0
0
86
131
26.51
65.16
6.1
1.6
—
—
—
0
0
61
82
15.45
48.28
2.6
2.7
30.39
28.54
u/l
0.25
61
68
98
321
19.82
35.05
17.9
6.2
—
—
—
0
0
101
458
15.70
25.50
22.7
7.3
0.71
0.70
%
0.08
101
434
101
459
15.64
25.45
22.6
7.2
2.65
2.91
%
0.68
101
439
101
460
15.59
25.38
22.7
7.3
9.05
8.69
%
0.85
101
441
101
463
15.41
25.17
22.2
7.1
52.07
57.91
%
6.23
101
448
101
470
15.02
24.60
22.7
7.3
34.03
27.33
%
7.70
101
453
102
495
15.56
23.77
22.4
7.4
0.57
0.59
e9/l
0.59
97
430
102
497
15.44
23.46
22.4
7.4
0.04
0.04
e9/l
0.53
97
433
102
504
15.05
22.89
22.5
7.4
2.10
1.89
e9/l
1.24
97
447
102
514
14.51
22.26
23.0
7.5
0.16
0.20
e9/l
2.33
97
454
85
346
7.41
20.53
8.1
4.0
145.83
23.06
e6/l
0.72
41
244
102
553
12.59
19.60
23.8
11.5
3.27
4.22
e9/l
6.62
97
485
76
301
5.93
18.26
15.4
6.0
—
—
—
0
0
88
398
7.06
18.00
6.8
5.8
37.66
36.28
g/l
1.39
88
381
89
413
7.05
17.48
7.0
3.2
5.89
6.11
ph
0.51
19
242
51
151
5.43
17.16
1.4
1.6
—
—
—
0
0
15
0
+∞
16.02
1.1
0.0
—
—
—
0
0
103
629
11.01
15.75
11.0
4.1
—
—
—
0
0
88
434
6.14
15.21
24.6
11.7
0.00
0.00
e9/l
0.50
80
355
95
510
7.33
14.55
5.9
3.4
0.00
0.00
estimate
-0.00
11
98
95
515
7.19
14.24
5.9
3.4
0.00
0.00
estimate
-0.00
12
99
95
526
6.91
13.57
6.0
3.4
0.00
0.00
estimate
—
10
89
21
16
15.90
13.09
1.1
1.1
—
—
—
0
0
22
38
6.99
12.84
1.3
1.4
179.00
296.34
miu/ml
—
6
20
22
22
12.19
12.19
1.1
1.1
—
—
—
0
0
60
252
4.04
11.96
4.9
3.1
—
—
estimate
—
0
0
43
144
4.26
11.76
4.4
2.9
0.82
0.99
e6/l
0.09
17
66
60
263
3.82
11.02
5.1
3.1
0.12
0.35
e6/l
1.47
38
190
94
572
5.42
10.46
10.3
5.4
6.44
6.80
mmol/l
1.01
94
547
56
246
3.60
10.04
4.9
4.0
89.25
91.08
%
0.19
56
241
61
302
3.29
8.71
5.1
3.4
38.51
38.29
e6/l
0.00
39
230
55
258
3.26
8.57
6.1
5.1
—
—
—
0
0
13
9
16.15
8.44
1.2
1.2
—
—
—
0
0
18
27
7.75
7.99
2.7
2.5
0.75
3.46
index
—
8
13
13
11
13.20
7.81
2.5
1.6
—
—
—
0
0
21
487
0.30
6.24
4.5
3.2
—
—
—
0
0
14
23
6.81
5.92
1.1
1.4
—
—
—
0
0
52
282
2.60
5.64
3.9
4.7
7.40
7.39
ph
0.86
37
206
14
27
5.78
5.29
1.1
1.1
—
—
—
0
0
31
134
2.83
5.20
1.6
1.4
—
—
—
0
0
16
48
3.73
4.82
3.7
2.9
24.13
24.87
mmol/l
0.42
16
48
68
453
2.31
4.32
9.4
8.2
1.20
1.20
mmol/l
0.47
58
406
30
141
2.55
4.21
2.5
2.3
—
—
—
0
0
35
178
2.42
4.15
4.4
2.6
593.70
552.61
mosm/kgh2o
0.54
30
157
21
84
2.85
4.00
18.6
9.5
—
—
—
0
0
37
198
2.31
3.89
2.9
2.7
—
—
—
0
0
16
57
3.11
3.71
21.1
10.5
24.94
24.84
mmol/l
0.04
16
57
6
6
10.48
3.54
1.5
1.5
620.17
509.50
u/ml
—
6
6
12
32
4.08
3.51
19.3
1.3
—
—
—
0
0
38
217
2.15
3.35
3.8
2.9
2.85
3.24
e6/l
0.19
33
196
76
565
2.12
3.25
6.1
4.2
—
23.43
—
0
14
17
69
2.73
3.14
2.1
3.7
57.38
74.21
e9/l
—
9
44
6
8
7.85
3.09
2.2
2.0
1.17
0.63
index
—
6
8
16
64
2.76
3.03
3.3
4.1
89.56
88.70
ng/l
0.01
16
58
7
13
5.67
2.92
5.3
3.8
3.02
3.75
e9/l
—
7
13
16
66
2.67
2.86
1.4
1.6
0.29
0.24
mg/l
—
10
31
7
14
5.26
2.77
1.6
1.1
—
—
—
0
0
8
19
4.45
2.73
4.8
3.5
50.13
58.01
%
—
8
19
22
382
0.47
2.59
3.4
3.7
15.64
46.96
ng/l
1.91
11
260
5
7
7.41
2.57
1.0
1.1
—
—
—
0
0
5
156
0.29
2.54
1.2
1.5
—
—
—
0
0
54
379
1.83
2.50
2.0
2.0
90.96
91.20
pmol/l
0.01
31
195
6
12
5.22
2.43
1.0
1.3
—
—
—
0
0
19
93
2.26
2.39
3.6
3.5
7.36
7.39
ph
1.29
12
63
7
19
3.86
2.19
1.9
1.1
—
—
—
0
0
31
192
1.86
2.08
1.6
2.0
—
—
—
0
0
105
959
3.09
2.07
25.5
15.0
22.96
24.01
mg/l
0.15
94
774
8
27
3.11
1.98
1.1
1.3
—
—
—
0
0
6
17
3.67
1.86
1.0
1.0
—
—
—
0
0
20
111
1.98
1.84
1.5
1.2
—
—
—
0
0
8
29
2.89
1.83
1.1
1.1
—
—
—
0
0
93
1011
0.48
1.82
14.8
13.3
—
—
—
0
0
42
295
1.69
1.81
2.6
2.3
—
—
—
0
0
16
82
2.11
1.80
1.2
1.3
—
—
—
0
0
30
192
1.77
1.79
4.1
3.4
28.82
344.89
ng/l
1.38
22
153
6
18
3.46
1.77
1.0
1.5
—
—
—
0
0
6
18
3.46
1.77
2.2
3.6
—
—
—
0
0
10
41
2.58
1.69
1.1
1.9
20.30
20.47
s
—
10
36
26
386
0.57
1.68
6.0
3.3
0.18
0.00
estimate
0.47
11
85
22
131
1.85
1.65
1.5
1.6
—
—
—
0
0
6
20
3.11
1.60
1.0
1.1
—
—
—
0
0
6
21
2.96
1.53
1.0
1.1
—
—
—
0
0
23
144
1.76
1.47
17.1
7.8
104.83
104.25
mmol/l
0.29
23
144
7
29
2.51
1.41
1.3
1.2
—
—
—
0
0
0
40
0.00
1.36
0.0
1.1
—
—
—
0
0
19
117
1.75
1.28
1.5
1.4
—
—
—
0
0
20
296
0.60
1.21
7.0
2.8
0.00
0.01
estimate
0.49
11
79
41
314
1.49
1.15
2.4
2.2
114.07
187.93
u/l
1.92
41
306
40
308
1.47
1.08
4.0
3.7
119.45
58.49
mg/l
0.58
28
204
5
22
2.33
1.04
18.0
1.6
—
—
—
0
0
29
214
1.48
0.96
1.2
1.3
5.56
2.55
g/l
—
10
144
52
430
1.40
0.93
3.0
2.8
—
—
estimate
—
0
0
23
164
1.51
0.89
2.6
2.4
13.15
14.19
umol/l
0.27
23
152
13
80
1.71
0.89
1.9
2.6
0.21
0.23
g/l
0.46
13
71
53
443
1.38
0.88
17.4
12.8
1.29
1.23
inr
0.27
44
359
8
46
1.80
0.84
2.7
2.0
—
0.08
estimate
—
0
13
8
47
1.76
0.82
13.8
1.4
—
—
—
0
0
17
237
0.67
0.77
8.2
6.9
—
—
—
0
0
9
55
1.69
0.76
1.3
1.1
—
—
—
0
0
7
39
1.85
0.74
15.4
1.3
—
—
—
0
0
34
273
1.36
0.70
1.4
1.3
—
—
—
0
0
5
27
1.89
0.69
1.6
1.1
—
—
—
0
0
5
27
1.89
0.69
1.0
1.1
2.00
37.57
e6/l
—
5
21
5
28
1.82
0.67
1.0
1.3
17.40
95.64
e6/l
—
5
22
42
352
1.31
0.65
2.0
1.8
—
—
—
0
0
10
63
1.65
0.64
6.8
3.9
—
—
—
0
0
8
49
1.68
0.64
13.8
1.4
—
—
—
0
0
8
49
1.68
0.64
13.9
1.4
—
—
—
0
0
8
50
1.65
0.63
14.5
1.4
—
—
—
0
0
8
50
1.65
0.63
13.8
1.4
—
—
—
0
0
19
141
1.42
0.61
2.9
2.3
25.53
24.34
%
0.08
19
133
0
22
0.00
0.60
0.0
1.2
—
—
—
0
0
0
22
0.00
0.60
0.0
1.4
—
—
—
0
0
5
87
0.55
0.59
1.0
1.1
—
—
—
0
0
11
73
1.56
0.59
1.5
1.2
—
—
—
0
0
6
39
1.57
0.54
1.0
1.1
—
—
—
0
0
6
39
1.57
0.54
1.2
1.2
—
—
—
0
0
9
65
1.42
0.52
1.3
2.8
—
—
—
0
0
19
148
1.34
0.47
1.2
1.4
114.29
398.79
titre
—
7
33
37
317
1.25
0.47
4.7
4.3
21.99
8.33
mg/mmol
0.67
24
213
0
15
0.00
0.41
0.0
1.7
—
1.67
—
0
15
0
17
0.00
0.41
0.0
1.6
—
0.17
—
0
12
22
264
0.79
0.39
5.1
3.7
0.00
0.00
estimate
-0.00
11
93
9
121
0.72
0.37
1.1
1.3
—
—
—
0
0
28
315
0.85
0.26
2.7
2.8
0.55
0.71
ug/l
1.02
19
160
5
38
1.33
0.23
5.0
2.6
—
—
—
0
0
5
39
1.30
0.23
1.2
1.4
—
—
—
0
0
10
123
0.79
0.21
1.5
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
88.56
—
0
10
0
12
0.00
0.21
0.0
2.5
—
3.98
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.5
—
107.25
—
0
12
0
12
0.00
0.21
0.0
2.5
—
1.19
—
0
12
0
13
0.00
0.21
0.0
16.7
—
907.23
—
0
13
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
11
133
0.81
0.21
1.6
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
2.04
—
0
6
6
50
1.21
0.20
1.3
1.2
—
—
—
0
0
7
59
1.20
0.18
1.9
3.8
1.24
1.22
mmol/l
—
7
54
16
179
0.88
0.13
2.4
2.5
16.23
14.96
nmol/l
0.29
16
173
5
48
1.04
0.09
2.6
2.2
0.42
0.67
%
—
5
48
7
84
0.82
0.07
2.0
2.5
—
7.66
—
0
5
9
87
1.04
0.07
3.0
4.5
2.97
58.56
ug/l
—
9
69
12
116
1.04
0.00
1.7
2.6
321.42
394.44
nmol/l
0.80
12
107
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.4
—
10.30
—
0
5
0
6
0.00
0.00
0.0
2.5
—
3.33
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
1.62
—
0
6
0
7
0.00
-0.00
0.0
3.7
—
55.64
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
2.43
—
0
7
0
7
0.00
-0.00
0.0
2.7
—
0.33
—
0
7
0
8
0.00
-0.00
0.0
10.9
—
0.51
—
0
8

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_HIV_INFECT_PARASITES_WIDE – Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).