Benign neoplasm of other and unspecified sites

CD2_BENIGN_OTHER_NOS

benign neoplasm: A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D36
  • Cause of death: ICD-10 D36

2 out of 7 registries used, show all original rules.

1077

4. Check minimum number of events

None

1077

5. Include endpoints

1381

6. Filter based on genotype QC (FinnGen only)

1254

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna locis aliis et non specificatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9119 5174 3872
Only index persons 7706 4485 3221
Unadjusted period prevalence (%)
Whole population 0.13 0.15 0.11
Only index persons 0.15 0.16 0.12
Median age at first event (years)
Whole population 50.01 50.24 49.59
Only index persons 47.98 48.44 47.33

-FinnGen-

Key figures

All Female Male
Number of individuals 1254 736 518
Unadjusted period prevalence (%) 0.25 0.26 0.24
Median age at first event (years) 50.05 48.05 52.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1293
Matched controls
12930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
6474.7
307.7
447
*
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
3195.3
307.7
406
*
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
68.2
129.6
71
11
22899
ICD-8 Finland
Benign neoplasm of other and unspecified organs and tissues
+∞
116.4
110
*
22550
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Peripheral nerves
+∞
115.4
109
*
D36.0
ICD-10 Finland
Benign neoplasm: Lymph nodes
+∞
100.3
95
*
D36.9
ICD-10 Finland
Benign neoplasm: Benign neoplasm of unspecified site
+∞
80.0
76
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
31.0
63.8
42
14
2258X
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Other specified sites of nervous system
+∞
62.0
59
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
6.5
39.2
65
104
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
8.4
32.6
43
53
DHB00
NOMESCO Finland
Excision of lesion of external nose
9.3
30.5
37
41
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
105.8
28.8
31
*
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
4.9
27.8
63
135
DHA10
NOMESCO Finland
Biopsy of cavity of nose
9.1
26.9
33
37
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
45.3
25.6
31
7
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.6
24.4
158
663
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.1
23.6
66
167
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
6.7
22.6
36
55
N03AX16
ATC
[U] pregabalin
1.9
22.6
338
1988
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
7.6
22.6
32
43
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
78.1
20.7
23
*
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
58.5
19.9
23
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.4
19.3
144
644
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
4.3
18.0
47
113
2401
FHL
Nerve exploration (includes biopsy and removal of local change)
23.4
16.5
23
10
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.4
16.4
115
499
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
16.4
102
419
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
4.0
16.3
47
122
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
6.2
16.0
27
44
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.0
15.9
73
256
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
14.8
341
2245
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
3.0
14.2
62
211
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.3
14.1
105
469
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
13.9
462
3328
N03AX12
ATC
[U] gabapentin; oral
1.8
13.8
226
1345
ACB99
NOMESCO Finland
Other operation for lesion of peripheral nerve: other or unspecified
53.9
13.8
16
*
Z31.5
ICD-10 Finland
Genetic counselling
2.6
13.6
80
320
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
141.4
13.5
14
*
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
5.6
13.4
25
45
S18
ICPC
Laceration/cut
1.6
13.3
610
4722
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
13.2
126
622
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
13.2
474
3468
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
70.6
12.6
14
*
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
12.5
12
*
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
16.0
12.2
19
12
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
12.1
447
3277
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.2
12.0
48
155
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
9.7
11.8
23
24
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
3.4
11.6
42
128
ZXA05
NOMESCO Finland
Left side
1.6
11.3
313
2139
ZXA00
NOMESCO Finland
Right side
1.6
11.3
338
2353
N02AX02
ATC
tramadol; systemic, rectal
1.5
11.2
544
4214
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
10.8
895
7704
ACB15
NOMESCO Finland
Excision of local lesion of tibial nerve
60.5
10.6
12
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
10.6
96
465
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
10.6
605
4823
SPAT1153
SPAT
Removal of sutures
1.5
10.5
387
2819
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
10.4
10
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.4
10.4
74
324
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
3.9
10.2
30
79
L17
ICPC
Foot/toe symptom/complaint
1.5
10.2
389
2849
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
9.9
250
1665
A02BC02
ATC
pantoprazole; systemic
1.5
9.6
861
7426
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
3.4
9.6
34
102
S04
ICPC
Lump/swelling localized
1.8
9.4
146
851
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.9
9.4
27
70
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
4.3
9.4
24
57
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.3
9.4
24
57
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.3
9.3
71
320
UJF32
NOMESCO Finland
Coloscopy
1.5
9.3
326
2339
A02BC03
ATC
lansoprazole; oral
1.5
9.2
358
2627
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
9.0
186
1175
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.1
9.0
37
122
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.7
8.9
48
184
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
8.8
196
1262
N02BE01
ATC
paracetamol; systemic, rectal
1.7
8.8
1133
10437
M79.6
ICD-10 Finland
Pain in limb
1.4
8.7
553
4445
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
8.7
270
1885
D33.30
ICD-10 Finland
Acoustic neuroma
7.7
8.7
19
25
R03AC02
ATC
salbutamol; inhalant
1.4
8.6
674
5616
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.4
8.6
58
248
N02BF01
ATC
gabapentin; oral
1.8
8.6
140
828
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
8.5
273
1917
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
90.6
8.4
9
*
2312
FHL
Extirpation or destruction
+∞
8.3
8
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
8.2
140
839
PJA10
NOMESCO Finland
Exploration of lymph nodes
3.8
8.1
24
64
N03AF02
ATC
oxcarbazepine; oral
2.6
8.1
45
176
A02BC05
ATC
esomeprazole; systemic
1.4
8.0
492
3912
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
8.0
127
745
R51
ICD-10 Finland
Headache
2.1
8.0
73
356
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
13.1
7.9
13
10
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
7.8
355
2673
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.7
434
3393
A02BC01
ATC
omeprazole; systemic
1.5
7.6
318
2356
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.1
7.5
30
98
SXC05
NOMESCO Finland
Other oral or dental procedure
2.0
7.4
80
414
R13
ICD-10 Finland
Dysphagia
1.9
7.4
97
536
ACB18
NOMESCO Finland
Excision of local lesion of brachial plexus
+∞
7.3
7
*
ACB13
NOMESCO Finland
Excision of local lesion of ulnar nerve
+∞
7.3
7
*
Q85.1
ICD-10 Finland
Tuberous sclerosis
+∞
7.3
7
*
H02AB06
ATC
prednisolone; systemic
1.4
7.3
571
4713
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.9
7.2
97
541
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.2
163
1053
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
4.5
7.2
17
38
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
30.2
7.2
9
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
7.1
356
2718
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
7.1
101
573
WX402
NOMESCO Finland
General anaesthesia
1.5
7.1
264
1907
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
7.1
141
883
R51.80
ICD-10 Finland
Headache
1.6
7.0
191
1290
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
7.0
72
367
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
7.0
125
760
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
6.9
284
2089
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
6.9
55
254
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
6.9
42
172
XKD00
NOMESCO Finland
Uroflowmetry
1.6
6.9
162
1057
M01AH05
ATC
etoricoxib; oral
1.4
6.8
754
6546
J02AC01
ATC
fluconazole; systemic
1.4
6.8
447
3574
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
2.7
6.8
34
126
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
6.8
201
1383
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
9.4
6.8
13
14
ZXE00
NOMESCO Finland
One hour or less
1.4
6.8
448
3585
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.7
192
1310
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.7
6.7
115
691
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
6.7
124
761
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
6.5
432
3458
SPAT1202
SPAT
Intra-articular injection
2.4
6.4
42
178
GAA31
NOMESCO Finland
Thoracoscopy
14.4
6.4
10
7
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
6.4
71
373
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
4.1
6.4
17
42
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
6.4
136
867
SPAT1301
SPAT
No procedures
1.4
6.3
355
2761
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
6.3
117
719
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.3
470
3826
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
6.3
158
1048
SPAT1312
SPAT
General health counselling
1.4
6.2
344
2665
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.6
6.2
35
138
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
2.6
6.2
35
138
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.2
464
3774
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
6.2
151
993
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
6.2
129
817
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
5.4
6.2
17
32
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
6.2
93
539
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.1
516
4272
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.1
258
1907
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
6.1
144
942
M01AC06
ATC
meloxicam; systemic, rectal
1.4
6.1
425
3421
J01DB01
ATC
cefalexin; oral
1.4
6.0
1009
9254
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
10.1
6.0
11
11
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
3.0
6.0
26
89

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
626
4540
1.73
20.48
2.4
2.2
—
—
—
0
0
188
1021
1.98
15.31
1.4
1.4
—
—
—
0
0
253
1530
1.81
14.78
1.4
1.3
—
—
—
0
0
677
5372
1.55
13.09
15.2
15.1
1.23
1.25
inr
0.39
561
4494
725
5903
1.52
12.00
7.3
7.5
1.21
1.21
mmol/l
0.32
643
5093
660
5293
1.50
11.58
7.7
6.7
1.21
1.21
mmol/l
0.37
623
4898
667
5374
1.50
11.35
3.2
2.8
—
—
estimate
—
0
0
725
5970
1.49
10.89
6.9
6.3
0.04
0.04
e9/l
0.00
636
5161
794
6663
1.50
10.83
10.3
9.8
4.05
4.11
e9/l
0.31
701
5837
723
5959
1.48
10.75
6.9
6.3
0.57
0.58
e9/l
1.06
632
5150
733
6073
1.48
10.51
6.9
6.4
1.84
1.90
e9/l
0.44
650
5372
740
6148
1.48
10.43
7.1
6.6
0.19
0.19
e9/l
0.09
664
5402
216
1377
1.68
10.20
7.8
8.7
7.41
7.41
ph
0.46
124
766
216
1377
1.68
10.20
7.8
8.7
5.19
5.09
kpa
1.07
210
1328
805
6821
1.48
10.11
6.2
5.3
6.61
6.68
mmol/l
0.49
775
6497
212
1368
1.66
9.52
7.8
8.7
1.36
0.94
mmol/l
0.96
174
1129
637
5216
1.44
9.22
5.3
5.1
35.71
35.67
g/l
0.06
595
4903
729
6161
1.42
8.60
7.4
6.8
11.32
11.53
umol/l
0.16
698
5909
478
3770
1.43
8.23
2.7
2.5
—
—
—
0
0
458
3594
1.42
8.08
4.3
4.2
7.40
7.40
ph
0.11
331
2609
472
3734
1.42
7.91
3.2
2.6
61.90
60.92
u/l
0.07
439
3476
121
703
1.80
7.90
3.5
3.7
4.34
4.54
pmol/l
1.57
105
627
388
2972
1.44
7.75
4.1
4.1
89.91
89.96
%
0.01
380
2913
179
1166
1.62
7.68
2.9
2.1
357.99
381.94
nmol/l
0.96
165
1080
654
5507
1.38
7.42
7.2
6.6
8.90
8.84
%
0.17
617
5186
711
6072
1.38
7.37
4.8
3.9
0.00
0.00
estimate
0.50
142
1276
717
6142
1.38
7.24
4.8
3.9
0.00
5.08
estimate
1.33
142
1310
720
6177
1.37
7.17
4.8
4.0
0.05
0.26
estimate
0.40
143
1232
650
5495
1.37
7.06
7.0
6.5
2.84
2.83
%
0.03
612
5166
370
2855
1.41
6.97
2.4
2.4
—
—
—
0
0
970
8765
1.43
6.94
9.9
8.4
77.59
79.74
u/l
0.64
928
8351
648
5493
1.36
6.83
7.1
6.6
0.74
0.69
%
1.27
612
5161
662
5631
1.36
6.82
7.0
6.5
27.84
27.53
%
0.29
628
5355
508
4152
1.37
6.73
3.7
3.7
2.36
2.36
mmol/l
0.72
458
3794
588
4932
1.35
6.53
4.3
3.5
6.31
6.22
ph
1.05
310
2805
341
2621
1.41
6.51
6.1
4.8
—
—
—
0
0
447
3610
1.36
6.28
3.6
3.2
—
—
—
0
0
294
2214
1.42
6.27
1.4
1.3
43.19
29.91
iu/ml
0.66
85
682
196
1366
1.51
6.22
1.8
1.7
—
—
—
0
0
1161
10940
1.60
6.12
20.8
16.5
23.13
24.25
mg/l
0.59
986
9062
455
3697
1.36
6.11
2.4
2.2
217.78
241.12
u/l
0.17
432
3513
421
3384
1.36
6.05
5.1
4.0
0.00
0.01
estimate
1.34
133
1190
645
5529
1.33
6.01
6.8
6.4
56.96
57.49
%
0.54
622
5303
960
8734
1.38
6.01
5.3
4.5
14.89
14.81
pmol/l
0.47
899
8068
59
299
2.02
5.87
1.6
1.3
11.91
10.46
u/l
0.28
48
239
1099
10253
1.48
5.87
6.3
5.5
1.85
1.91
mu/l
1.09
1030
9525
33
131
2.56
5.81
1.4
1.7
26.01
35.49
ng/l
0.40
33
131
1181
11200
1.63
5.74
24.2
19.4
139.76
139.66
mmol/l
0.76
1162
10992
335
2618
1.38
5.69
1.9
1.8
1.25
1.23
mg/l
0.04
261
2035
1181
11212
1.62
5.57
24.2
19.6
3.96
3.97
mmol/l
1.00
1158
10990
548
4626
1.32
5.54
4.9
3.8
0.01
0.04
estimate
1.69
119
1056
407
3300
1.34
5.41
4.7
4.3
—
—
—
0
0
535
4512
1.32
5.40
4.4
3.9
24.12
55.50
ng/l
1.46
365
3243
110
706
1.61
5.03
1.4
1.3
16.82
40.58
au/ml
—
6
58
229
1712
1.41
5.01
2.2
2.1
—
—
—
0
0
400
3269
1.32
4.96
3.2
3.2
0.63
0.44
e6/l
0.44
309
2432
830
7478
1.31
4.95
5.7
4.8
629.00
1895.22
e6/l
1.05
13
110
118
776
1.57
4.87
10.4
10.6
93.36
93.91
%
0.31
118
771
114
744
1.58
4.86
10.5
10.8
0.65
0.65
%
0.02
114
738
28
113
2.51
4.81
1.6
1.5
282.91
349.66
mu/l
0.75
23
89
337
2700
1.34
4.77
1.3
1.3
0.97
1.63
u/ml
1.41
82
744
267
2071
1.36
4.66
1.4
1.3
10.55
11.69
u/ml
0.10
112
808
198
1463
1.42
4.62
2.2
2.4
169.85
118.63
ug/g
0.74
164
1172
116
776
1.54
4.46
10.2
10.4
1.22
1.31
%
0.55
116
770
506
4316
1.28
4.45
4.1
3.9
44.17
114.58
e6/l
2.70
383
3072
163
1172
1.45
4.41
2.1
2.3
0.22
0.21
g/l
0.39
152
1096
186
1374
1.41
4.34
2.6
2.8
10.01
7.87
umol/l
0.49
161
1222
326
2631
1.32
4.34
2.8
2.6
6.28
6.15
e6/l
0.05
293
2416
469
3975
1.28
4.31
7.0
6.3
—
—
—
0
0
449
3793
1.28
4.21
3.5
3.3
29.70
80.53
e6/l
1.78
363
2932
214
1635
1.37
4.09
1.2
1.2
—
—
—
0
0
466
3967
1.27
4.08
3.8
3.3
32.63
32.69
u/l
0.01
435
3761
218
1671
1.37
4.08
1.5
1.4
431.43
523.53
titre
0.32
42
363
56
318
1.80
4.05
1.9
2.1
5076.55
5338.77
u/l
0.02
11
131
75
463
1.66
4.04
3.1
3.5
129.52
8690.50
u/ml
0.84
61
404
256
2021
1.33
3.94
3.7
3.5
0.81
0.82
mmol/l
0.58
245
1914
603
5312
1.25
3.90
2.5
2.5
78.08
77.34
nmol/l
0.25
545
4830
372
3100
1.28
3.83
2.6
2.3
2.95
2.85
mg/l
0.31
311
2672
113
779
1.49
3.80
2.8
2.5
20.43
20.47
au/ml
0.00
20
80
418
3539
1.27
3.77
6.4
6.3
—
—
—
0
0
143
1034
1.43
3.77
7.8
9.3
—
—
—
0
0
29
134
2.19
3.75
1.9
1.3
—
—
nmol/l
—
0
0
361
3005
1.28
3.74
2.6
2.8
327.45
343.12
umol/l
2.18
326
2666
150
1097
1.42
3.71
7.5
8.0
1.15
1.38
mmol/l
3.54
150
1075
62
373
1.70
3.70
1.9
1.7
264.52
300.14
mu/l
0.77
56
340
329
2715
1.28
3.64
5.2
4.0
1.02
1.02
kg/l
0.06
208
1826
60
362
1.69
3.55
1.5
1.5
233.91
277.58
ug/g
1.02
40
224
1198
11561
1.49
3.51
14.6
12.4
25.62
26.05
u/l
0.49
1173
11259
208
1620
1.34
3.50
4.5
5.8
1.03
1.03
mmol/l
0.04
195
1500
420
3587
1.25
3.47
3.4
3.2
903.82
1282.91
ng/l
2.34
353
3077
612
5447
1.23
3.46
3.3
3.1
118.73
126.88
ug/l
0.36
565
5088
978
9170
1.27
3.41
24.1
20.4
13.70
13.65
%
0.57
970
9057
133
968
1.42
3.39
2.3
2.5
6.58
7.34
ug/l
0.22
122
869
177
1353
1.36
3.37
1.3
1.3
—
—
—
0
0
47
269
1.78
3.36
1.5
1.3
1157.39
862.95
e6/l
0.15
38
208
164
1242
1.37
3.31
3.8
4.4
52.81
23.86
ug/l
0.26
135
1020
113
802
1.45
3.31
1.3
1.3
148.93
226.46
u/ml
0.68
106
748
125
905
1.42
3.29
3.4
3.1
130.35
199.28
ng/l
2.77
113
830
130
949
1.41
3.27
2.8
3.8
80.50
88.69
ng/l
0.48
112
831
46
264
1.77
3.27
1.4
1.2
5.85
46.87
e6/l
1.03
34
196
251
2027
1.30
3.25
2.3
2.6
13.41
12.95
umol/l
0.42
222
1894
66
419
1.61
3.24
1.2
1.2
—
—
—
0
0
177
1362
1.35
3.23
2.9
2.7
1.75
1.85
%
0.78
155
1227
250
2023
1.29
3.19
3.0
2.9
0.95
1.11
e6/l
0.42
153
1086
21
91
2.33
3.18
1.8
2.0
36.27
38.23
%
0.21
21
91
1202
11636
1.47
3.15
26.8
21.4
76.49
77.46
umol/l
0.42
1191
11515
51
306
1.69
3.12
7.9
4.0
3.94
3.89
mmol/l
0.26
51
301
245
1987
1.29
3.07
1.8
1.8
1128.56
1179.88
nmol/l
0.34
178
1517
287
2380
1.26
3.00
1.5
1.5
2.13
2.45
g/l
2.84
170
1475
142
1069
1.37
2.99
3.4
2.8
68.41
70.79
e9/l
0.34
99
782
1168
11264
1.38
2.99
18.5
14.7
—
—
—
0
0
59
375
1.60
2.91
7.1
3.8
1.12
1.38
mmol/l
2.50
59
367
289
2408
1.26
2.90
3.0
3.0
2.47
2.45
mmol/l
0.87
262
2187
50
308
1.65
2.80
1.3
1.2
572.58
503.03
mg/l
0.28
50
294
124
924
1.38
2.79
1.2
1.2
—
—
—
0
0
1091
10447
1.28
2.71
6.7
6.5
38.71
39.41
mmol/mol
2.25
1018
9818
536
4789
1.20
2.71
2.1
1.9
1.36
1.37
mmol/l
0.14
448
4071
74
504
1.50
2.71
1.5
1.9
10.50
7.67
iu/ml
0.20
22
124
83
580
1.46
2.68
2.4
2.4
—
—
—
0
0
76
522
1.48
2.67
1.6
1.4
26.71
28.38
iu/l
0.15
60
449
13
49
2.67
2.62
1.2
1.2
1.94
2.05
umol/l
0.30
13
41
104
761
1.40
2.62
1.8
1.8
1.54
1.41
g/l
0.17
90
704
273
2290
1.24
2.57
4.9
4.0
204.17
354.33
ng/l
1.17
213
1794
820
7646
1.20
2.52
3.6
3.4
51.52
50.05
u/l
0.13
771
7237
122
923
1.36
2.52
2.8
2.3
12.84
13.33
nmol/l
0.27
109
834
1108
10655
1.28
2.49
5.7
5.2
5.93
5.95
mmol/l
0.25
1026
9811
363
3147
1.21
2.48
1.5
1.4
—
—
—
0
0
1220
11904
1.44
2.41
31.4
25.0
253.55
250.45
e9/l
0.90
1201
11681
450
3991
1.20
2.40
3.8
3.7
—
0.77
—
0
13
6
12
5.02
2.40
1.7
1.2
—
—
—
0
0
1220
11905
1.44
2.40
31.3
24.9
90.93
91.16
fl
1.09
1208
11788
81
577
1.43
2.39
1.1
1.1
—
0.92
u/ml
—
0
5
1220
11907
1.44
2.37
31.3
24.9
30.20
30.33
pg
2.00
1208
11788
1220
11908
1.43
2.36
31.4
25.0
4.48
4.48
e12/l
0.07
1197
11654
1220
11908
1.43
2.36
32.0
25.5
40.38
40.30
%
0.23
1207
11783
1220
11909
1.43
2.35
31.4
25.0
6.58
6.73
e9/l
1.89
1197
11647
48
308
1.58
2.33
1.2
1.3
—
—
—
0
0
1220
11911
1.43
2.32
31.7
25.1
134.28
134.89
g/l
0.75
1208
11794
28
155
1.82
2.31
1.9
1.3
0.52
12.27
nmol/l
0.50
28
146
104
780
1.36
2.28
1.2
1.2
—
—
—
0
0
10
34
2.96
2.28
2.1
1.7
82.56
96.44
nmol/24h
—
10
34
74
524
1.44
2.27
1.3
1.2
—
—
—
0
0
22
113
1.96
2.26
1.0
1.2
—
—
—
0
0
127
987
1.32
2.21
2.5
2.3
0.27
0.54
e6/l
1.39
114
935
21
107
1.98
2.21
5.8
5.3
74.46
48.23
u/ml
—
9
32
185
1511
1.26
2.20
2.6
3.5
4.07
4.99
e9/l
1.30
157
1326
17
80
2.14
2.19
4.5
3.0
39.33
40.17
%
—
9
44
12
48
2.51
2.19
1.4
1.1
—
70.50
%
—
0
8
268
2286
1.22
2.14
3.0
2.9
493.73
526.62
mosm/kgh2o
1.98
231
2018
559
5097
1.17
2.08
13.1
11.7
0.00
0.00
e9/l
0.56
467
4201
39
246
1.60
2.06
1.5
1.3
—
—
—
0
0
7
20
3.51
2.05
1.3
1.1
—
—
—
0
0
23
125
1.86
2.03
1.6
1.2
—
—
—
0
0
209
1749
1.23
2.01
2.3
2.6
23.11
22.70
%
0.15
186
1645
7
21
3.35
1.96
2.0
1.5
—
—
—
0
0
5
11
4.56
1.94
10.0
5.5
0.30
0.17
%
—
5
11
121
953
1.30
1.94
2.8
3.0
9.68
10.81
g/l
2.87
112
883
136
1088
1.28
1.93
5.3
4.5
0.92
0.98
%
0.13
45
345
141
1135
1.27
1.91
2.2
2.2
0.00
0.02
estimate
0.78
22
233
7
22
3.19
1.88
2.4
1.9
—
—
—
0
0
12
52
2.32
1.88
1.3
1.3
160.50
177.94
mmol/24h
0.47
12
52
32
197
1.64
1.88
1.3
1.7
0.72
0.83
g/l
0.25
27
159
50
342
1.48
1.87
1.3
1.2
1.48
10.46
u/ml
—
5
57
20
108
1.87
1.82
1.2
1.1
—
—
—
0
0
372
3316
1.17
1.80
3.9
3.4
0.00
0.03
estimate
0.77
118
1010
384
3438
1.17
1.75
1.8
1.7
19.96
20.32
nmol/l
0.18
323
2922
221
1887
1.21
1.75
2.3
2.6
2.33
2.32
g/l
0.07
197
1764
6
18
3.34
1.74
1.0
1.2
—
—
—
0
0
42
283
1.50
1.71
1.2
1.2
4.08
3.76
mmol/l
0.80
42
270
81
615
1.34
1.70
1.2
1.2
—
—
—
0
0
1123
10909
1.22
1.69
5.4
5.2
4.63
4.64
mmol/l
0.15
1058
10212
77
581
1.35
1.69
2.2
2.3
0.00
1.40
estimate
0.51
19
182
58
418
1.41
1.68
1.5
1.6
20.72
13.39
u/ml
—
10
101
65
479
1.38
1.65
1.5
1.2
0.17
1.03
u/ml
0.83
11
32
193
1638
1.21
1.63
1.6
1.6
—
—
—
0
0
27
166
1.64
1.62
1.6
1.2
—
—
—
0
0
127
1033
1.25
1.60
5.2
4.4
0.62
0.65
%
0.06
40
323
136
1117
1.24
1.58
3.0
2.4
36.73
41.37
u/l
0.30
108
937
39
264
1.49
1.57
1.4
1.7
—
—
—
0
0
124
1011
1.25
1.54
2.5
3.0
65.28
66.79
g/l
1.50
114
934
141
1167
1.23
1.53
3.7
3.5
1.80
1.85
mmol/l
0.05
132
998
5
15
3.34
1.52
1.2
1.3
0.01
1.03
u/ml
—
5
15
17
93
1.84
1.52
1.7
1.4
36.83
31.33
%
0.26
12
57
26
162
1.62
1.50
1.6
1.6
—
—
—
0
0
26
162
1.62
1.50
1.6
1.6
—
—
—
0
0
26
162
1.62
1.50
1.6
1.6
—
—
—
0
0
26
162
1.62
1.50
1.6
1.6
—
—
—
0
0
108
870
1.26
1.49
1.7
1.4
—
—
—
0
0
38
259
1.48
1.49
4.5
4.1
—
—
—
0
0
12
58
2.08
1.49
1.7
3.0
2347.92
940.03
u/ml
0.38
12
58
29
186
1.57
1.49
2.1
1.7
—
—
—
0
0
174
1477
1.21
1.48
1.8
1.5
—
—
—
0
0
125
1032
1.23
1.41
5.3
4.5
0.12
0.12
%
0.01
34
290
9
40
2.26
1.40
3.8
3.0
—
—
—
0
0
20
119
1.69
1.38
2.6
2.6
—
—
—
0
0
5
17
2.95
1.36
3.6
3.4
—
—
—
0
0
19
112
1.71
1.35
5.4
4.2
—
—
—
0
0
27
176
1.55
1.32
2.3
2.6
—
—
—
0
0
130
1086
1.22
1.32
4.0
4.2
7.37
7.36
ph
0.46
93
795
6
24
2.51
1.30
1.0
1.8
3.16
3.87
mmol/l
—
6
19
6
24
2.51
1.30
1.0
1.0
—
—
—
0
0
1133
11068
1.19
1.29
6.3
5.9
2.69
2.70
mmol/l
0.24
1059
10320
67
519
1.31
1.28
2.4
1.9
1.49
1.87
ug/l
0.18
67
468
153
1306
1.19
1.25
1.8
1.6
—
—
—
0
0
112
930
1.22
1.22
4.7
3.9
—
—
—
0
0
45
332
1.37
1.20
1.2
1.2
—
—
—
0
0
142
1212
1.19
1.17
4.0
3.6
7.37
7.38
ph
0.80
75
708
10
50
2.01
1.16
1.1
1.2
121.30
473.69
u/l
—
10
45
13
222
0.58
1.14
3.1
3.8
19.97
24.34
mg/l
—
6
157
46
344
1.35
1.14
1.6
1.3
193.36
234.82
miu/ml
0.44
27
163
123
1040
1.20
1.13
5.6
4.8
0.00
0.14
%
2.32
31
264
404
4359
0.89
1.11
3.3
3.2
—
—
—
0
0
47
355
1.34
1.10
1.2
1.2
96.00
94.71
titre
—
5
34
31
218
1.43
1.10
1.8
1.5
—
—
—
0
0
32
227
1.42
1.08
4.4
5.0
2.71
2.76
mmol/l
0.02
22
154
98
815
1.22
1.07
4.5
3.7
5.15
5.15
kpa
0.02
91
790
53
410
1.31
1.06
2.7
3.8
42.94
52.67
mg/l
0.30
46
351
45
340
1.34
1.06
8.0
10.9
—
—
—
0
0
53
411
1.30
1.04
2.7
3.8
86.58
62.05
mg/l
0.30
46
352
41
306
1.35
1.04
3.0
3.3
1.05
1.88
index
0.81
19
161
99
827
1.21
1.04
2.3
2.6
—
—
—
0
0
1109
10853
1.15
1.03
5.4
5.1
1.49
1.47
mmol/l
0.91
1038
10087
19
287
0.66
1.02
1.5
1.8
—
—
—
0
0
1064
10385
1.14
1.02
4.5
4.3
1.27
1.30
mmol/l
0.87
986
9577
9
47
1.92
1.02
3.8
2.7
—
—
—
0
0
29
205
1.42
1.01
1.5
1.4
112.67
174.42
au/ml
—
9
58
31
222
1.41
1.01
1.5
1.4
—
—
—
0
0
13
76
1.72
0.99
1.1
1.2
—
—
—
0
0
5
23
2.18
0.98
1.2
3.6
—
33.42
—
0
6
84
696
1.22
0.97
3.8
3.5
24.32
24.26
mmol/l
0.06
84
689
216
1937
1.14
0.97
1.9
1.8
—
—
—
0
0
45
346
1.31
0.96
5.9
7.9
1.25
1.31
mmol/l
0.21
40
306
209
1873
1.14
0.95
3.1
3.0
3.78
2.64
e6/l
0.50
111
937
550
5201
1.10
0.95
2.3
2.2
97.95
96.12
pmol/l
0.41
277
2749
46
356
1.30
0.94
1.2
1.2
—
1233.00
—
0
10
17
109
1.57
0.93
3.6
3.7
15.33
11.46
index
—
6
65
12
70
1.72
0.92
1.6
3.0
16.27
16.42
%
0.06
12
70
27
372
0.72
0.92
1.3
1.7
—
—
—
0
0
94
795
1.20
0.90
4.6
3.7
7.41
7.42
ph
0.28
79
667
47
368
1.29
0.89
2.7
3.5
10.45
3.42
ratio
0.55
25
214
270
2469
1.12
0.89
1.7
1.7
25000488.71
27705434.31
pmol/l
0.04
216
2061
29
211
1.38
0.89
1.3
1.4
—
9.50
—
0
6
13
205
0.63
0.87
2.0
1.6
—
—
—
0
0
8
43
1.87
0.87
1.8
2.7
25.27
211.63
ug/l
—
8
36
46
361
1.28
0.86
1.9
1.6
0.21
0.24
g/l
1.17
46
346
430
4037
1.10
0.85
3.3
3.4
7.28
7.48
mmol/l
0.43
373
3443
28
376
0.74
0.83
1.4
1.6
—
—
—
0
0
28
375
0.74
0.82
1.4
1.6
—
—
—
0
0
20
138
1.46
0.82
2.1
2.1
1.56
0.84
mmol/l
0.58
20
132
21
147
1.44
0.80
1.8
1.2
—
—
—
0
0
18
122
1.48
0.80
3.0
2.2
—
—
—
0
0
28
373
0.75
0.79
1.4
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
52.06
—
0
24
26
347
0.74
0.75
1.4
1.7
—
—
—
0
0
9
53
1.70
0.75
1.0
1.0
1832.11
1581.66
miu/ml
—
9
53
12
75
1.61
0.75
1.2
1.2
—
—
—
0
0
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
17
116
1.47
0.74
1.2
1.3
—
—
—
0
0
16
108
1.49
0.73
1.3
1.2
0.23
1.47
u/ml
1.00
11
54
24
176
1.37
0.73
1.6
1.2
7.58
5.78
u/ml
0.14
12
77
33
255
1.30
0.72
1.2
1.3
58.63
61.99
mmol/l
0.19
27
209
11
68
1.62
0.71
1.3
1.6
—
—
—
0
0
7
40
1.75
0.71
1.6
2.9
0.59
0.60
mmol/l
—
7
40
9
57
1.58
0.71
2.9
2.5
—
—
—
0
0
20
143
1.40
0.70
1.3
1.3
—
76.60
—
0
8
7
41
1.71
0.70
1.1
1.1
—
—
—
0
0
412
3895
1.08
0.69
4.0
4.2
12.89
9.12
mg/mmol
0.40
254
2443
18
127
1.42
0.68
1.5
1.3
—
—
—
0
0
105
923
1.15
0.67
1.8
1.7
—
—
—
0
0
404
3821
1.08
0.67
3.4
3.5
48.72
49.39
mg/l
0.02
252
2458
21
154
1.37
0.65
1.2
1.2
—
—
—
0
0
39
315
1.25
0.63
1.1
1.2
—
—
—
0
0
63
535
1.19
0.63
1.5
1.9
1.58
1.48
g/l
0.36
50
476
35
279
1.26
0.62
2.7
2.1
133.28
129.30
g/l
0.42
29
225
52
434
1.21
0.62
5.7
4.1
25.16
24.97
mmol/l
0.26
47
407
0
20
0.00
0.60
0.0
3.2
—
—
—
0
0
29
228
1.28
0.58
1.1
1.1
0.85
2.40
u/ml
1.17
15
122
32
255
1.26
0.58
1.8
1.5
207.03
264.31
pmol/l
0.19
32
250
6
35
1.72
0.57
1.0
1.5
—
—
—
0
0
45
376
1.20
0.55
2.0
1.6
1.13
1.20
g/l
0.75
45
358
18
134
1.35
0.53
1.6
1.6
55.50
60.44
%
0.18
12
86
6
39
1.54
0.53
1.2
1.3
2.45
1.25
%
—
6
32
13
91
1.43
0.53
1.2
1.2
—
—
—
0
0
12
83
1.45
0.52
1.0
1.0
—
—
—
0
0
22
170
1.30
0.51
5.7
2.2
0.67
0.90
%
1.31
11
119
6
40
1.50
0.51
1.3
1.7
26.67
32.02
%
—
6
40
13
92
1.42
0.50
3.3
3.1
3.19
17.82
mg/l
—
7
65
6
41
1.47
0.50
1.2
1.5
0.00
0.07
estimate
—
6
41
34
411
0.82
0.50
1.2
1.1
1.55
1.55
g/l
0.07
34
411
14
101
1.39
0.49
1.2
1.1
—
—
—
0
0
12
167
0.72
0.49
1.4
1.6
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
7
45
1.56
0.49
40.7
34.3
107.86
123.69
ug/l
—
7
35
66
578
1.15
0.48
1.0
1.1
—
—
—
0
0
13
93
1.40
0.48
1.0
1.5
—
—
—
0
0
352
3356
1.07
0.47
5.8
5.3
1.95
2.36
ug/l
1.54
319
3035
10
68
1.47
0.47
1.5
1.4
211.00
167.90
pmol/l
—
10
68
21
164
1.29
0.46
2.0
1.4
0.25
0.31
nmol/l
0.23
14
127
23
183
1.26
0.45
1.0
1.0
0.14
2.37
u/ml
—
5
71
32
382
0.83
0.43
1.2
1.1
0.51
0.69
ratio
—
5
45
15
113
1.33
0.42
1.7
1.3
476.80
135185.96
e6/l
—
10
73
12
162
0.74
0.42
1.4
1.5
—
—
—
0
0
6
94
0.64
0.42
1.0
1.2
354.67
384.73
nmol/l
—
6
83
22
176
1.25
0.42
1.1
1.2
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
157.60
310.19
pmol/l
—
5
21
0
16
0.00
0.41
0.0
11.3
—
5.24
—
0
16
15
114
1.32
0.40
1.3
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
3.6
—
—
—
0
0
104
951
1.10
0.40
3.9
3.9
1.23
1.23
mmol/l
0.11
89
830
0
18
0.00
0.40
0.0
5.9
—
8.16
—
0
18
52
456
1.15
0.39
2.4
2.6
—
—
—
0
0
16
124
1.29
0.38
1.6
2.3
—
—
—
0
0
17
133
1.28
0.38
1.2
1.3
—
—
—
0
0
9
67
1.35
0.38
1.0
1.6
4.37
7.71
ug/l
—
9
55
36
308
1.17
0.37
2.4
1.6
11968.10
13598.17
e6/l
0.12
29
218
61
544
1.13
0.37
1.9
1.9
—
—
—
0
0
12
158
0.76
0.37
1.7
2.3
—
—
—
0
0
9
69
1.31
0.37
1.8
1.4
1.08
1.19
nmol/l
—
9
48
62
554
1.13
0.37
5.3
3.9
—
—
—
0
0
23
189
1.22
0.36
1.1
1.0
4.46
5.78
u/ml
—
8
93
15
117
1.29
0.35
1.3
1.4
147548.33
96145.25
e6/l
—
6
57
9
126
0.71
0.35
1.1
1.1
—
—
—
0
0
21
172
1.22
0.34
2.6
2.6
—
—
—
0
0
131
1223
1.08
0.34
1.8
1.6
—
—
—
0
0
39
340
1.15
0.33
1.2
1.3
—
—
—
0
0
21
253
0.83
0.33
1.7
2.5
—
—
—
0
0
30
349
0.86
0.32
1.5
1.6
1203.21
988.96
mu/l
0.39
24
292
18
220
0.82
0.32
2.7
1.7
—
—
—
0
0
28
327
0.85
0.32
1.0
1.1
—
—
—
0
0
17
137
1.24
0.32
1.4
1.4
5595.17
1717.88
e6/l
0.46
12
84
29
249
1.17
0.30
3.8
3.5
0.77
0.82
nmol/l
0.45
23
208
7
54
1.30
0.30
1.6
1.8
—
—
—
0
0
11
84
1.31
0.30
1.2
1.2
20.55
11.68
u/l
0.39
11
74
10
130
0.77
0.29
1.0
1.1
—
—
—
0
0
7
57
1.23
0.29
1.6
2.8
2200.00
1946.83
ml
—
7
52
11
85
1.30
0.28
1.3
1.6
9.00
12.17
umol/l
1.45
11
79
9
118
0.76
0.27
1.3
1.2
—
—
—
0
0
35
309
1.14
0.27
1.2
1.1
3.24
7.02
eliau/ml
—
5
36
38
426
0.89
0.26
1.2
1.2
0.89
0.91
g/l
0.15
38
426
105
1119
0.93
0.26
1.4
1.5
—
—
—
0
0
194
2026
0.95
0.25
3.6
3.1
0.71
0.77
ug/l
0.48
137
1269
19
160
1.19
0.25
2.3
1.9
—
—
—
0
0
23
265
0.87
0.24
2.2
2.4
233.18
99.71
ug/min
0.31
13
157
5
38
1.32
0.23
1.2
1.2
18.04
32.62
%
—
5
33
21
181
1.16
0.22
1.0
1.0
0.70
2.30
u/ml
—
9
82
15
125
1.20
0.22
1.2
1.4
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
0.50
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
61.33
—
0
12
95
1005
0.94
0.21
1.3
1.4
—
—
—
0
0
13
108
1.21
0.20
1.1
1.3
—
—
—
0
0
6
50
1.20
0.19
1.2
1.3
—
—
—
0
0
7
58
1.21
0.18
1.1
1.2
—
—
—
0
0
7
63
1.11
0.17
1.1
1.2
27.24
30.60
umol/l
—
7
57
12
101
1.19
0.16
1.3
1.1
—
—
—
0
0
14
120
1.17
0.16
1.6
1.7
—
—
—
0
0
8
70
1.14
0.16
1.5
2.8
6.35
8.20
mmol/l
—
8
70
8
72
1.11
0.16
1.0
1.1
—
—
—
0
0
19
168
1.13
0.15
1.0
1.0
4.85
3.64
u/ml
—
7
73
53
497
1.07
0.15
1.3
1.6
0.25
0.38
mg/l
1.65
23
227
36
332
1.09
0.15
1.9
1.9
4.55
4.12
iu/l
0.13
16
137
14
121
1.16
0.15
1.1
1.1
—
—
—
0
0
19
169
1.13
0.14
1.2
1.2
—
—
—
0
0
28
256
1.10
0.14
1.2
1.2
—
—
—
0
0
23
208
1.11
0.14
3.1
3.6
3.95
4.25
e9/l
0.32
23
208
113
1172
0.96
0.13
1.8
2.1
3.49
3.49
ratio
0.01
88
933
77
806
0.95
0.13
1.3
1.2
110.43
135.17
u/ml
0.29
31
320
54
570
0.95
0.12
2.1
1.7
—
—
—
0
0
17
152
1.12
0.12
6.8
2.3
31.65
32.71
pg
0.38
17
152
5
44
1.14
0.10
1.2
1.3
64.80
57.26
%
—
5
34
55
575
0.95
0.10
5.2
3.6
1.02
1.02
ratio
0.21
44
532
10
114
0.88
0.09
1.0
1.2
—
—
—
0
0
12
107
1.12
0.08
2.1
2.5
—
—
—
0
0
92
894
1.03
0.08
2.8
2.5
6.05
6.07
ph
0.11
53
610
5
63
0.79
0.08
1.4
1.3
138.10
150.63
nmol/l
—
5
63
6
72
0.83
0.07
1.0
1.2
—
4.59
—
0
19
8
76
1.05
0.07
1.5
1.4
77.50
81.79
umol/l
—
8
76
9
84
1.07
0.07
1.2
1.0
—
—
—
0
0
26
275
0.94
0.06
7.0
4.8
—
—
—
0
0
12
132
0.91
0.06
1.1
1.2
—
—
—
0
0
23
244
0.94
0.06
4.5
3.3
6.73
7.42
mmol/l
0.88
23
238
15
161
0.93
0.05
1.3
1.0
2.43
2.13
eliau/ml
—
6
67
43
417
1.03
0.04
1.0
1.1
—
—
—
0
0
39
401
0.97
0.03
3.8
3.6
371.16
288.88
mg/l
0.12
19
175
20
209
0.96
0.03
1.1
1.1
—
—
—
0
0
20
209
0.96
0.03
1.1
1.1
—
—
—
0
0
31
301
1.03
0.02
4.1
3.1
1.32
1.53
mmol/l
1.73
31
294
13
123
1.06
0.01
2.5
2.7
—
—
—
0
0
10
94
1.06
0.01
1.2
1.1
—
—
—
0
0
23
224
1.03
0.00
1.3
1.3
218.63
267.31
u/ml
0.38
11
129
87
864
1.01
0.00
1.6
1.8
3.50
3.49
mmol/l
0.02
62
624
10
96
1.04
0.00
2.2
2.5
983.10
1029.49
mg
—
10
96
16
158
1.01
0.00
1.0
1.1
0.62
6.07
u/ml
—
5
60
21
208
1.01
0.00
1.0
1.0
—
—
—
0
0
20
201
0.99
0.00
1.1
1.1
7.52
20.35
au/ml
—
6
58
12
123
0.98
0.00
2.3
2.5
—
43.37
—
0
18
20
203
0.98
0.00
1.1
1.1
—
—
—
0
0
27
267
1.01
0.00
3.3
3.5
57.74
57.84
%
0.01
27
267
5
54
0.93
0.00
1.0
1.1
147.78
167.04
iu/ml
—
5
54
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.06
—
0
7
9
95
0.95
-0.00
1.2
1.1
142.56
105.80
pmol/l
—
9
95
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.2
10.40
9.09
mm/h
—
5
57
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
30.86
—
0
5
5
58
0.86
-0.00
1.8
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3.74
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
4.20
—
0
5
6
65
0.92
-0.00
2.7
3.9
1.50
0.88
index
—
6
65
0
6
0.00
-0.00
0.0
1.7
—
442.17
—
0
6
7
76
0.92
-0.00
1.3
1.8
71.86
100.49
ng/l
—
7
76
0
7
0.00
-0.00
0.0
1.4
—
353.00
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
21
210
1.00
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_OTHER_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_OTHER_NOS 1.242 [1.09, 1.41] < 0.001
Birth year 0.991 [0.98, 1.0] 0.039

During the follow-up period (1.1.1998 — 31.12.2019), 549 out of 2966 females with CD2_BENIGN_OTHER_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_OTHER_NOS 1.366 [1.18, 1.57] < 0.001
Birth year 0.985 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 531 out of 2412 males with CD2_BENIGN_OTHER_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_OTHER_NOS.

N-year risk Females Males
1 0.159% 0.289%
5 0.643% 1.611%
10 1.644% 3.828%
15 3.185% 6.966%
20 5.527% 11.602%

Relationships between endpoints

Index endpoint: CD2_BENIGN_OTHER_NOS – Benign neoplasm of other and unspecified sites

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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