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Benign neoplasm: Other/unspecified site

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_NOS

benign neoplasm: A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites.

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Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D36.7&, D36.9&
  • Hospital discharge: ICD-9 — 2298B|2899
  • Hospital discharge: ICD-8 — 2289
  • Cause of death: ICD-10 — D36.7&, D36.9&
  • Cause of death: ICD-9 — 2298B|2899
  • Cause of death: ICD-8 — 2289

2 out of 7 registries used, show all original rules.

641

4. Check minimum number of events

None

641

5. Include endpoints

None

641

6. Filter based on genotype QC (FinnGen only)

580

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4683 2655 1987
Only index persons 3950 2292 1658
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.06
Only index persons 0.08 0.08 0.06
Median age at first event (years)
Whole population 51.34 50.73 51.95
Only index persons 48.91 48.60 49.34

-FinnGen-

Key figures

All Female Male
Number of individuals 580 341 239
Unadjusted period prevalence (%) 0.12 0.12 0.11
Median age at first event (years) 50.42 47.31 54.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
598
Matched controls
5980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
+∞
307.7
404
*
22899
ICD-8 Finland
Benign neoplasm of other and unspecified organs and tissues
+∞
118.8
110
*
D36.9
ICD-10 Finland
Benign neoplasm: Benign neoplasm of unspecified site
+∞
81.1
76
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
142.6
38.2
40
*
DHB00
NOMESCO Finland
Excision of lesion of external nose
17.9
22.0
34
20
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
18.1
20.2
31
18
DHA10
NOMESCO Finland
Biopsy of cavity of nose
17.2
18.0
28
17
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
5.0
16.3
36
76
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.1
14.3
65
229
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.7
13.5
76
302
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.5
13.4
47
141
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
5.3
9.9
20
39
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
9.2
223
1526
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.4
8.8
63
280
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.0
8.2
23
59
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.7
7.9
25
70
R01AD08
ATC
fluticasone; nasal
1.7
7.8
172
1135
UJF32
NOMESCO Finland
Coloscopy
1.7
7.8
163
1060
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
18.6
7.6
11
6
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.4
7.4
51
223
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.8
7.1
35
129
J02AC01
ATC
fluconazole; systemic
1.6
7.1
231
1679
R51
ICD-10 Finland
Headache
2.7
7.1
37
141
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.3
7.0
51
229
UDM02
NOMESCO Finland
Sinoscopy
3.8
7.0
21
57
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.3
6.9
53
244
DJW00
NOMESCO Finland
Removal of local lesion of nasal septum
40.5
6.8
8
*
A02BC03
ATC
lansoprazole; oral
1.6
6.7
178
1226
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.5
136
880
J31.0
ICD-10 Finland
Chronic rhinitis
2.1
6.3
59
294
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
6.3
6
*
J01AA02
ATC
doxycycline; systemic
1.6
6.1
456
3957
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
6.1
173
1208
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.5
6.1
20
58

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
328
2479
1.72
9.45
15.8
13.8
1.25
1.24
inr
0.12
275
2066
307
2365
1.61
7.55
5.4
4.9
35.87
35.66
g/l
0.29
283
2231
277
2101
1.59
7.14
2.5
2.2
—
—
—
0
0
340
2716
1.58
6.95
7.0
7.1
1.21
1.21
mmol/l
0.02
300
2355
104
615
1.84
6.80
2.1
1.7
—
—
—
0
0
92
524
1.89
6.76
3.3
2.0
353.12
381.52
nmol/l
0.83
85
490
229
1696
1.57
6.34
3.4
2.6
58.21
63.01
u/l
0.50
210
1573
461
4009
1.65
6.19
10.3
8.4
79.68
79.43
u/l
0.03
435
3805
372
3089
1.54
5.98
6.2
5.0
6.64
6.66
mmol/l
0.09
353
2943
20
59
3.47
5.91
1.6
1.4
32.22
29.11
ng/l
0.10
20
59
109
695
1.70
5.45
1.4
1.3
—
—
—
0
0
302
2430
1.49
5.43
7.6
6.3
1.21
1.21
mmol/l
0.62
280
2251
78
458
1.81
5.19
1.4
1.4
—
—
—
0
0
86
525
1.75
5.02
2.2
2.2
0.22
0.21
g/l
0.44
80
490
299
2443
1.45
4.73
3.3
2.7
—
—
estimate
—
0
0
339
2842
1.45
4.64
7.9
6.7
12.30
11.44
umol/l
0.43
324
2717
542
5023
1.84
4.63
21.5
16.2
22.03
24.09
mg/l
0.86
466
4167
333
2783
1.44
4.63
7.3
6.3
1.85
1.92
e9/l
0.22
306
2455
164
1196
1.51
4.62
1.8
1.7
1.42
1.22
mg/l
0.32
124
951
45
230
2.03
4.53
2.9
3.4
157.94
1913.67
u/ml
1.39
36
198
97
629
1.65
4.53
6.6
7.9
7.41
7.42
ph
0.25
55
373
359
3050
1.44
4.52
11.0
9.9
4.06
4.08
e9/l
0.07
327
2667
255
2037
1.44
4.48
4.7
3.8
27.12
79.72
ng/l
1.00
180
1487
96
623
1.64
4.46
6.5
7.9
1.54
1.00
mmol/l
0.74
79
525
407
3556
1.45
4.29
5.4
4.7
—
3.01
—
0
9
325
2729
1.42
4.25
7.4
6.3
0.57
0.58
e9/l
0.29
293
2350
228
1803
1.43
4.16
4.1
3.5
30.02
31.84
u/l
0.53
213
1706
235
1869
1.42
4.15
4.0
3.5
2.36
2.36
mmol/l
0.39
206
1712
109
743
1.57
4.14
1.2
1.2
—
—
—
0
0
325
2738
1.41
4.12
7.5
6.3
0.04
0.04
e9/l
0.14
294
2357
54
305
1.85
4.09
3.9
3.8
4.39
4.57
pmol/l
0.75
47
269
192
1482
1.44
3.97
4.9
4.3
—
—
—
0
0
333
2830
1.40
3.94
7.5
6.5
0.19
0.19
e9/l
0.01
308
2478
216
1709
1.41
3.87
2.7
2.3
—
—
—
0
0
200
1561
1.42
3.87
5.0
4.0
0.00
0.01
estimate
0.78
71
541
182
1400
1.43
3.81
2.5
2.2
3.00
2.91
mg/l
0.18
146
1209
32
155
2.12
3.74
2.1
1.7
286.32
293.55
mu/l
0.06
27
143
91
609
1.58
3.73
2.8
2.8
11.36
8.06
umol/l
0.46
78
538
332
2839
1.38
3.68
5.1
4.0
0.09
0.55
estimate
0.40
77
560
509
4698
1.56
3.68
6.6
5.5
1.82
1.94
mu/l
1.68
474
4338
209
1661
1.40
3.60
4.1
4.1
7.40
7.40
ph
0.12
156
1187
209
1663
1.39
3.57
3.8
3.2
—
—
—
0
0
257
2120
1.37
3.51
5.3
3.9
0.02
0.05
estimate
0.78
61
484
546
5139
1.72
3.48
24.8
19.2
139.69
139.71
mmol/l
0.06
538
5040
328
2815
1.37
3.48
5.2
4.0
0.00
5.86
estimate
0.80
76
598
141
1052
1.45
3.44
3.4
3.0
485.39
537.71
mosm/kgh2o
2.39
124
924
304
2584
1.36
3.40
7.2
6.3
27.46
27.63
%
0.10
293
2461
28
134
2.14
3.39
2.0
2.1
349.20
5030.96
u/l
—
5
45
546
5145
1.70
3.39
24.8
19.4
3.97
3.98
mmol/l
0.26
535
5035
26
121
2.20
3.37
1.7
1.3
12.55
10.66
u/l
0.24
21
94
65
412
1.65
3.32
3.4
3.7
87.81
84.70
ng/l
0.09
53
370
165
1275
1.41
3.31
2.4
2.3
—
—
—
0
0
324
2791
1.35
3.27
5.2
4.0
0.00
0.00
estimate
-0.00
73
575
33
171
1.98
3.26
1.5
1.4
255.54
297.39
ug/g
0.63
23
102
284
2405
1.34
3.18
2.5
2.5
79.39
77.35
nmol/l
0.53
254
2176
297
2534
1.34
3.16
7.0
6.2
57.75
57.40
%
0.20
291
2428
297
2540
1.34
3.08
7.7
6.3
8.98
8.86
%
0.28
284
2393
438
3977
1.38
3.01
5.7
4.4
14.98
14.79
pmol/l
0.74
410
3651
295
2529
1.33
2.97
7.7
6.3
0.75
0.69
%
1.16
282
2371
295
2531
1.33
2.95
7.6
6.3
2.79
2.87
%
0.28
282
2380
8
17
4.75
2.92
1.1
1.4
2.07
1.92
umol/l
—
8
12
155
1210
1.38
2.89
6.8
4.7
—
—
—
0
0
190
1535
1.35
2.84
3.3
3.2
0.56
0.47
e6/l
0.10
146
1121
218
1798
1.33
2.84
7.5
6.2
—
—
—
0
0
265
2248
1.32
2.83
4.9
3.6
6.30
6.20
ph
0.74
147
1286
83
580
1.50
2.81
3.3
4.3
95.85
31.12
ug/l
0.32
72
486
216
1783
1.33
2.79
3.6
3.3
43.61
102.29
e6/l
0.75
175
1367
203
1665
1.33
2.73
2.4
2.2
315.52
267.28
u/l
0.16
191
1582
404
3647
1.33
2.72
4.5
4.1
—
0.20
—
0
5
155
1224
1.36
2.67
2.7
2.8
5.98
5.00
e6/l
0.25
142
1125
26
134
1.98
2.64
1.3
1.2
626.46
516.80
mg/l
0.23
26
127
543
5162
1.56
2.59
19.3
14.4
—
—
—
0
0
40
239
1.72
2.58
1.7
2.0
13.72
6.57
iu/ml
0.35
13
57
555
5305
1.64
2.56
15.2
12.3
26.44
26.00
u/l
0.28
543
5161
32
180
1.82
2.53
1.4
1.7
12.26
10.63
u/ml
—
5
34
567
5454
1.76
2.50
32.0
24.8
253.28
249.89
e9/l
0.56
560
5351
92
673
1.43
2.48
1.7
1.4
—
—
—
0
0
139
1093
1.35
2.45
2.8
2.9
2.47
2.45
mmol/l
0.72
124
983
203
1687
1.31
2.44
3.2
3.2
1045.30
1192.08
ng/l
0.29
166
1437
567
5458
1.75
2.43
32.5
25.2
40.31
40.29
%
0.03
562
5399
567
5458
1.75
2.43
32.0
24.7
4.45
4.48
e12/l
0.60
558
5343
567
5458
1.75
2.43
32.0
24.8
6.62
6.72
e9/l
0.58
558
5342
6
12
5.04
2.40
2.5
1.8
—
—
—
0
0
567
5460
1.74
2.40
32.4
24.9
133.90
134.83
g/l
0.78
562
5401
155
1244
1.33
2.38
1.3
1.3
0.65
1.64
u/ml
1.65
37
354
68
474
1.49
2.35
2.5
2.5
0.16
0.27
e6/l
0.86
60
448
13
53
2.49
2.29
1.2
1.1
—
—
—
0
0
12
47
2.58
2.28
1.4
1.1
—
—
—
0
0
384
3484
1.29
2.26
4.0
3.4
60.64
48.56
u/l
0.78
357
3284
120
935
1.35
2.23
2.3
2.5
12.39
13.09
umol/l
0.46
105
868
100
760
1.38
2.17
1.5
1.3
393.33
466.03
titre
0.31
18
189
284
2492
1.27
2.16
3.4
3.0
107.60
120.28
ug/l
0.76
258
2325
22
116
1.93
2.13
1.5
1.1
10.13
26.55
e6/l
0.73
16
88
454
4224
1.31
2.12
24.5
20.3
13.74
13.65
%
0.77
449
4181
155
1266
1.30
2.08
5.3
3.8
—
0.38
—
0
13
254
2214
1.26
2.01
2.1
2.0
1.40
1.35
mmol/l
0.32
212
1859
64
456
1.45
2.00
8.1
8.6
—
—
—
0
0
15
70
2.17
2.00
2.5
2.9
—
—
—
0
0
89
674
1.38
1.98
2.6
2.3
209.15
117.96
ug/g
0.79
75
535
116
917
1.33
1.96
3.1
3.3
0.80
0.81
mmol/l
0.56
110
869
82
614
1.39
1.96
1.3
1.3
—
—
—
0
0
233
2020
1.25
1.91
4.4
4.0
58.45
102.60
e6/l
0.87
181
1426
104
813
1.34
1.90
2.2
2.4
21.26
22.46
%
0.36
91
762
505
4792
1.35
1.89
7.1
6.6
38.78
39.45
mmol/mol
1.22
471
4522
102
796
1.34
1.88
2.2
2.0
—
—
—
0
0
36
230
1.60
1.86
1.3
1.2
—
—
—
0
0
42
281
1.53
1.80
1.3
1.3
—
—
—
0
0
57
407
1.44
1.78
4.1
3.9
—
—
—
0
0
19
102
1.89
1.78
1.5
1.1
—
—
—
0
0
34
217
1.60
1.78
2.0
2.0
1.43
2.88
ug/l
0.45
34
197
76
573
1.37
1.75
1.9
1.6
—
—
—
0
0
93
724
1.34
1.75
1.6
1.6
—
—
—
0
0
30
187
1.64
1.72
1.3
1.2
—
—
—
0
0
15
75
2.03
1.71
1.1
1.3
—
—
—
0
0
92
719
1.33
1.69
5.4
5.7
1.02
1.04
mmol/l
0.19
86
669
188
1614
1.24
1.64
6.7
6.5
—
—
—
0
0
5
14
3.59
1.62
1.2
1.1
—
—
—
0
0
84
654
1.33
1.59
2.6
3.3
4.04
5.10
e9/l
0.97
73
577
7
26
2.71
1.58
1.4
1.3
33.46
17.09
umol/l
—
7
21
149
1252
1.25
1.57
5.5
4.2
1.02
1.02
kg/l
0.13
90
851
512
4898
1.32
1.57
6.1
5.3
5.94
5.97
mmol/l
0.20
474
4521
57
420
1.39
1.53
2.7
2.3
13.34
13.14
nmol/l
0.06
51
374
108
877
1.28
1.51
2.4
2.5
2.31
2.32
g/l
0.04
94
815
14
72
1.97
1.50
2.0
2.9
—
—
—
0
0
38
261
1.49
1.47
1.1
1.1
—
104.43
titre
—
0
7
522
5016
1.32
1.47
5.6
5.2
4.53
4.64
mmol/l
1.60
492
4679
16
87
1.86
1.47
1.1
1.1
0.81
1.99
u/ml
—
9
48
33
220
1.53
1.47
1.7
1.3
22.57
26.57
iu/l
0.28
27
185
108
881
1.28
1.46
1.9
1.7
1039.41
1184.75
nmol/l
0.96
75
672
64
485
1.36
1.46
5.5
4.5
0.00
0.17
%
1.18
15
118
64
485
1.36
1.46
7.5
7.5
1.16
1.34
mmol/l
1.16
64
478
5
16
3.14
1.44
2.4
1.4
74.80
53.81
nmol/24h
—
5
16
24
150
1.63
1.40
1.4
1.3
235.92
254.08
miu/ml
0.08
13
71
11
53
2.10
1.39
5.4
4.8
100.30
46.91
u/ml
—
6
18
64
489
1.35
1.39
3.6
2.8
72.83
69.50
e9/l
0.25
44
358
63
481
1.35
1.37
5.3
4.2
0.13
0.16
%
0.11
15
130
9
41
2.21
1.37
2.1
1.9
33.24
40.06
%
—
9
41
66
509
1.33
1.35
5.2
4.2
1.17
0.98
%
0.22
18
157
63
483
1.34
1.34
5.4
4.1
0.74
0.57
%
0.31
19
144
9
42
2.16
1.34
1.0
1.3
—
—
—
0
0
26
169
1.56
1.31
1.1
1.2
—
378.00
—
0
5
131
1112
1.23
1.26
1.5
1.4
2.04
2.51
g/l
2.76
78
662
13
70
1.88
1.24
4.8
2.2
0.76
0.84
%
—
7
45
261
2366
1.18
1.24
13.9
11.3
0.00
0.00
e9/l
0.74
233
1943
62
483
1.32
1.20
4.5
4.1
7.36
7.36
ph
0.08
47
342
49
369
1.36
1.19
2.8
2.5
34.04
16.14
au/ml
—
8
29
6
26
2.32
1.19
1.0
1.0
2406.17
1509.46
miu/ml
—
6
26
162
1414
1.20
1.17
2.8
2.8
328.46
343.20
umol/l
1.12
145
1263
23
150
1.55
1.16
1.3
1.3
—
—
—
0
0
175
1542
1.19
1.14
4.2
3.5
0.00
0.06
estimate
0.63
61
470
27
184
1.49
1.13
4.9
4.0
1.09
1.31
mmol/l
0.95
27
178
35
478
0.72
1.13
1.3
1.4
—
—
—
0
0
517
5003
1.25
1.06
5.5
5.1
1.45
1.47
mmol/l
0.47
484
4642
12
67
1.81
1.05
2.0
2.8
105.58
105.81
mmol/l
0.06
12
67
12
67
1.81
1.05
2.0
2.8
1.20
1.19
mmol/l
0.33
12
67
12
67
1.81
1.05
2.0
2.8
3.94
4.02
mmol/l
0.27
12
67
54
422
1.31
1.04
3.7
3.6
1.23
1.23
mmol/l
0.12
47
368
525
5092
1.25
1.03
6.5
5.9
2.62
2.71
mmol/l
1.27
494
4739
5
22
2.28
1.03
2.6
2.9
—
—
—
0
0
121
1043
1.20
1.00
1.4
1.3
55.08
32.69
iu/ml
0.56
33
333
30
215
1.42
0.99
1.4
1.2
0.15
2.15
u/ml
—
6
13
7
135
0.51
0.99
1.3
1.9
—
—
—
0
0
5
23
2.18
0.98
39.4
32.7
87.40
110.47
ug/l
—
5
17
5
23
2.18
0.98
2.4
1.5
1.14
0.91
nmol/l
—
5
15
76
628
1.24
0.96
2.9
2.8
1.89
1.80
%
0.34
68
571
45
348
1.32
0.95
2.2
1.6
1.32
1.59
g/l
0.25
40
321
495
4783
1.20
0.94
4.6
4.3
1.31
1.29
mmol/l
0.14
452
4406
49
384
1.30
0.94
1.7
1.5
—
—
—
0
0
7
37
1.90
0.94
1.0
1.1
—
7.72
—
0
11
13
79
1.66
0.88
1.5
1.1
2.57
3.22
u/ml
—
7
37
110
954
1.19
0.86
1.3
1.3
12.36
13.02
u/ml
0.03
51
363
11
64
1.73
0.86
1.2
1.2
—
—
—
0
0
38
292
1.32
0.85
5.6
2.4
0.62
0.61
%
0.12
38
292
193
1754
1.15
0.84
3.4
3.5
48.18
52.30
mg/l
0.07
117
1123
10
57
1.77
0.84
2.3
2.0
—
—
—
0
0
18
121
1.50
0.83
1.3
1.1
4.41
3.76
mmol/l
0.99
18
112
53
428
1.26
0.83
1.2
1.2
—
—
—
0
0
17
113
1.52
0.83
5.6
3.0
—
—
—
0
0
203
1854
1.14
0.82
3.5
3.4
7.08
7.47
mmol/l
0.64
174
1560
47
376
1.27
0.80
4.1
3.8
7.41
7.42
ph
0.36
40
322
10
163
0.61
0.79
1.2
1.8
—
—
—
0
0
12
74
1.63
0.78
2.3
1.2
—
—
—
0
0
125
1106
1.16
0.78
1.8
1.7
56250496.54
20675084.00
pmol/l
0.27
96
919
159
1433
1.15
0.78
1.5
1.4
—
—
—
0
0
34
262
1.32
0.76
6.1
3.7
1.02
1.02
ratio
0.02
26
249
6
34
1.77
0.76
1.2
1.0
—
—
—
0
0
120
1061
1.16
0.76
4.8
4.1
188.37
373.03
ng/l
0.87
99
821
9
53
1.71
0.75
1.3
1.3
—
—
—
0
0
9
53
1.71
0.75
1.0
1.6
—
—
—
0
0
11
172
0.63
0.74
1.2
1.6
—
—
—
0
0
11
172
0.63
0.74
1.3
1.8
—
—
—
0
0
11
172
0.63
0.74
1.2
1.8
—
—
—
0
0
56
463
1.23
0.73
5.5
2.8
4.69
4.39
kpa
0.47
56
448
258
2408
1.13
0.73
2.3
2.1
99.36
95.67
pmol/l
0.58
126
1253
6
107
0.56
0.73
1.3
1.5
1.29
0.89
nmol/l
—
6
88
5
25
2.01
0.73
2.6
2.7
—
—
—
0
0
11
170
0.64
0.71
1.2
1.8
—
—
—
0
0
101
886
1.17
0.71
3.4
2.9
2.79
2.46
e6/l
0.12
54
434
12
77
1.57
0.69
1.1
1.0
6.24
4.37
u/ml
—
5
41
11
69
1.61
0.68
1.2
1.3
—
116.66
—
0
5
195
1796
1.13
0.68
4.3
4.2
13.46
9.09
mg/mmol
0.27
117
1110
22
293
0.74
0.66
1.1
1.1
—
—
—
0
0
5
28
1.79
0.66
2.4
1.9
52.60
58.93
ug/l
—
5
28
7
44
1.60
0.65
1.0
1.1
—
1.90
—
0
7
63
536
1.20
0.64
4.9
3.4
1.78
2.10
mmol/l
0.22
57
457
37
298
1.26
0.62
5.7
2.5
1.31
1.17
%
0.37
37
298
10
63
1.60
0.62
5.9
2.1
30.40
32.52
pg
—
10
63
33
263
1.27
0.61
4.3
4.0
—
—
—
0
0
8
51
1.58
0.60
1.9
2.0
—
—
—
0
0
65
558
1.18
0.60
5.5
3.4
7.38
7.38
ph
0.34
41
326
0
20
0.00
0.60
0.0
1.5
—
83.11
—
0
20
0
20
0.00
0.60
0.0
1.2
—
164.69
—
0
20
12
80
1.51
0.60
1.2
1.7
—
—
—
0
0
12
80
1.51
0.60
1.1
1.1
—
—
—
0
0
12
80
1.51
0.60
1.3
1.7
—
—
—
0
0
12
80
1.51
0.60
1.2
1.7
—
—
—
0
0
12
80
1.51
0.60
1.2
1.7
—
—
—
0
0
12
80
1.51
0.60
1.1
1.1
—
—
—
0
0
8
52
1.55
0.59
1.0
1.1
—
—
—
0
0
34
273
1.26
0.59
2.6
2.5
—
—
—
0
0
59
504
1.19
0.58
3.2
2.4
42.00
35.55
u/l
0.25
49
426
61
523
1.19
0.58
2.3
2.1
0.00
0.03
estimate
0.50
14
101
49
412
1.21
0.57
2.1
1.7
—
—
—
0
0
27
212
1.29
0.56
2.5
2.7
—
—
—
0
0
10
65
1.55
0.55
1.2
1.2
—
—
—
0
0
6
37
1.63
0.55
1.8
3.9
16.22
16.48
%
—
6
37
97
868
1.14
0.54
2.0
1.8
—
—
—
0
0
9
62
1.46
0.53
1.2
1.4
—
—
—
0
0
6
39
1.54
0.53
1.2
1.3
—
—
—
0
0
176
1635
1.11
0.53
1.8
1.7
19.62
20.60
nmol/l
0.38
150
1392
34
278
1.24
0.52
2.1
2.1
0.00
0.01
estimate
—
10
86
6
98
0.61
0.52
2.8
1.9
—
—
—
0
0
12
167
0.71
0.49
1.1
1.1
1.62
1.56
g/l
0.40
12
167
18
136
1.33
0.49
1.1
1.2
—
—
—
0
0
7
49
1.43
0.46
1.3
1.1
—
—
—
0
0
5
82
0.61
0.46
1.2
2.2
—
—
—
0
0
43
367
1.18
0.45
1.1
1.3
—
—
—
0
0
55
481
1.16
0.44
1.4
1.4
—
—
—
0
0
17
131
1.31
0.42
1.1
1.6
—
—
—
0
0
12
87
1.39
0.42
3.0
3.1
4.03
4.32
e9/l
0.18
12
87
5
33
1.52
0.41
1.0
1.2
186.80
172.37
pmol/l
—
5
33
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
28
232
1.22
0.40
1.8
2.0
1.88
1.58
g/l
0.71
20
204
8
60
1.34
0.40
10.4
4.3
—
—
—
0
0
10
71
1.42
0.39
1.9
1.8
—
—
—
0
0
20
161
1.25
0.37
1.4
1.2
—
—
—
0
0
162
1527
1.08
0.36
5.7
5.5
1.75
2.45
ug/l
1.48
142
1379
6
42
1.43
0.35
1.3
1.1
141.83
96.95
pmol/l
—
6
42
6
46
1.31
0.33
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.3
1.5
—
—
—
0
0
11
83
1.33
0.32
1.0
1.0
—
—
—
0
0
20
165
1.22
0.31
2.3
2.9
1.56
1.54
mg/l
0.03
20
148
16
129
1.25
0.30
9.8
4.9
—
—
—
0
0
10
75
1.34
0.30
1.1
1.0
1.17
2.52
u/ml
—
5
40
11
84
1.32
0.30
1.7
1.5
—
—
—
0
0
14
174
0.80
0.30
1.1
1.2
0.90
0.90
g/l
0.01
14
174
16
194
0.82
0.28
1.1
1.1
—
—
—
0
0
9
116
0.77
0.27
1.2
2.9
—
—
—
0
0
13
160
0.81
0.26
1.0
1.1
—
—
—
0
0
23
198
1.17
0.25
1.7
1.9
98.42
505.05
ug/l
1.15
23
186
22
189
1.17
0.24
2.2
1.5
1.11
1.20
g/l
0.83
22
183
11
87
1.27
0.24
1.0
1.1
—
—
—
0
0
19
161
1.19
0.24
8.1
11.1
—
—
—
0
0
6
85
0.70
0.24
2.5
1.6
—
—
—
0
0
5
38
1.32
0.23
1.4
1.2
—
—
—
0
0
22
191
1.16
0.22
4.9
3.6
468.36
213.44
mg/l
0.31
14
79
21
182
1.16
0.21
2.2
1.5
0.21
0.24
g/l
0.85
21
176
5
42
1.19
0.21
2.0
3.1
751.80
1121.52
mg
—
5
42
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
47.50
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
49.66
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
28.08
—
0
13
0
13
0.00
0.21
0.0
1.1
—
46.82
—
0
13
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
9
112
0.80
0.20
5.0
2.9
12.06
8.29
pmol/l
—
9
112
14
119
1.18
0.18
1.3
3.2
48.86
33.98
umol/l
0.33
14
107
43
397
1.09
0.18
1.8
2.5
—
—
—
0
0
12
142
0.84
0.17
5.0
3.1
1.00
1.80
index
—
6
81
196
2017
0.96
0.17
3.7
3.3
—
—
—
0
0
14
120
1.17
0.16
3.3
2.8
58.29
57.62
%
0.06
14
120
45
419
1.08
0.16
2.7
2.7
6.04
6.06
ph
0.05
24
287
12
102
1.18
0.15
2.0
1.5
—
—
—
0
0
26
238
1.10
0.13
1.5
1.5
0.21
0.35
mg/l
1.11
14
103
9
106
0.85
0.13
2.2
1.3
—
—
—
0
0
88
915
0.96
0.13
3.4
3.2
0.71
0.78
ug/l
0.36
58
578
38
357
1.07
0.11
1.3
1.3
84.55
143.57
u/ml
0.68
11
146
59
563
1.05
0.11
1.6
1.6
—
—
—
0
0
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
6
55
1.09
0.09
2.3
2.4
—
—
—
0
0
6
56
1.07
0.08
1.3
2.5
—
—
—
0
0
42
401
1.05
0.08
1.5
1.8
3.52
3.52
mmol/l
0.02
30
297
7
64
1.09
0.08
1.3
1.5
0.20
0.19
nmol/l
—
7
45
7
65
1.08
0.08
2.3
2.3
—
—
—
0
0
25
265
0.94
0.07
1.9
2.0
—
—
—
0
0
27
256
1.06
0.06
2.0
1.8
—
—
—
0
0
57
554
1.03
0.05
1.4
1.5
—
—
—
0
0
10
92
1.09
0.03
1.1
1.2
—
—
—
0
0
16
155
1.03
0.00
1.3
1.4
—
—
—
0
0
18
177
1.02
0.00
2.6
3.5
3.50
2.94
ratio
—
9
103
10
102
0.98
0.00
1.0
1.2
—
—
—
0
0
14
141
0.99
0.00
2.3
2.1
3.63
3.89
iu/l
—
8
60
5
50
1.00
0.00
1.6
1.2
—
—
—
0
0
5
50
1.00
0.00
2.4
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
6.03
—
0
8
5
52
0.96
-0.00
3.2
2.4
—
58.79
—
0
8
0
8
0.00
-0.00
0.0
3.6
—
7.25
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
4.20
—
0
5
5
58
0.86
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
1.72
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
68.57
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_NOS 1.162 [1.01, 1.34] 0.041
Birth year 0.996 [0.99, 1.0] 0.306

During the follow-up period (1.1.1998 — 31.12.2019), 364 out of 1726 females with CD2_BENIGN_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_NOS 1.229 [1.03, 1.46] 0.02
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 353 out of 1351 males with CD2_BENIGN_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_NOS.

N-year risk Females Males
1 0.138% 0.241%
5 0.732% 1.341%
10 1.722% 3.462%
15 3.384% 6.531%
20 6.018% 10.979%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_NOS – Benign neoplasm: Other/unspecified site

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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