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Melanoma in situ, other sites/unspecified

DOID Endpoint Browser PheWeb

CD2_INSITU_MELANOMA_NOS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

135

4. Check minimum number of events

None

135

5. Include endpoints

None

135

6. Filter based on genotype QC (FinnGen only)

125

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 125 65 60
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 67.42 64.21 70.91

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
127
Matched controls
1270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
5161.1
132.3
104
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
18.2
50.2
48
41
D03.8
ICD-10 Finland
Melanoma in situ of other sites
+∞
28.2
26
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
43.0
24.7
30
9
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
293.0
24.5
24
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.9
21.5
42
85
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.3
19.5
61
188
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.9
19.3
36
69
L57.0
ICD-10 Finland
Actinic keratosis
5.5
17.3
44
112
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
6.2
15.5
31
63
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
7.3
15.3
25
41
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
15.7
11.9
19
14
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
39.0
11.5
14
*
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
+∞
10.6
10
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
9.7
10.0
20
24
TQW99
NOMESCO Finland
Other minor procedure on skin
5.7
9.9
20
40
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
8.8
9.9
21
28
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
23.9
9.6
13
6
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
107.7
9.6
10
*
D03.5
ICD-10 Finland
Melanoma in situ of trunk
39.8
9.2
11
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.6
9.1
24
61
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
53.8
8.8
10
*
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
29.8
8.6
11
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
35.9
8.2
10
*
S18
ICPC
Laceration/cut
3.0
8.0
84
500
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
7.0
7.6
18
29
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
84.8
7.5
8
*
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
84.8
7.5
8
*
SPAT1153
SPAT
Removal of sutures
2.7
7.0
59
308
C43
ICD-10 Finland
Malignant melanoma of skin
42.4
6.8
8
*
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
42.4
6.8
8
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
6.7
30
110
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
73.4
6.5
7
*
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
8.4
6.3
13
17

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
63
159
6.88
26.33
1.7
1.3
—
—
—
0
0
103
453
7.74
22.29
4.6
2.2
—
—
—
0
0
38
111
4.46
12.29
1.6
1.3
—
—
—
0
0
64
411
2.12
4.18
4.0
3.2
7.20
7.50
mmol/l
0.26
53
344
60
384
2.07
3.88
3.3
2.3
—
—
—
0
0
103
815
2.40
3.73
5.5
4.4
14.96
14.96
pmol/l
0.00
94
736
83
612
2.03
3.49
4.3
4.1
0.00
0.00
estimate
-0.00
23
135
61
406
1.97
3.43
4.2
3.2
30.65
56.88
mg/l
0.91
44
271
7
10
7.33
3.41
1.3
1.2
20.34
15.90
ng/l
—
7
10
84
626
2.01
3.38
4.3
4.2
0.00
0.03
estimate
0.50
21
125
83
617
2.00
3.35
4.2
4.1
0.00
11.68
estimate
0.50
23
139
75
539
1.96
3.34
3.6
2.7
—
—
estimate
—
0
0
24
115
2.34
3.14
4.0
1.9
507.83
408.13
nmol/l
0.37
24
107
75
549
1.89
3.06
6.0
4.8
35.53
35.10
g/l
0.29
70
515
60
419
1.82
2.75
5.4
3.9
7.85
9.16
mg/mmol
0.09
42
268
24
123
2.17
2.68
2.0
1.8
—
—
—
0
0
83
643
1.84
2.67
12.8
9.9
3.90
4.19
e9/l
0.56
72
565
39
240
1.90
2.65
2.9
3.2
544.77
519.19
mosm/kgh2o
0.35
31
207
48
317
1.83
2.62
3.6
2.9
344.86
348.54
umol/l
0.10
42
266
51
349
1.77
2.44
4.0
4.3
0.00
0.00
estimate
-0.00
21
122
63
460
1.73
2.39
3.7
4.1
0.00
0.00
estimate
-0.00
17
113
25
136
2.04
2.39
1.2
1.4
—
—
—
0
0
50
342
1.76
2.39
3.3
3.6
0.00
0.00
estimate
-0.00
16
107
65
479
1.73
2.39
3.8
3.7
6.18
6.22
ph
0.10
34
264
118
1064
2.54
2.35
25.8
17.9
25.23
24.91
mg/l
0.04
105
900
73
558
1.72
2.33
9.6
7.0
1.22
1.21
mmol/l
0.58
66
510
105
894
2.01
2.32
13.1
8.3
76.23
81.05
u/l
0.91
96
842
78
609
1.73
2.29
10.7
7.8
1.22
1.21
mmol/l
1.41
63
524
43
285
1.77
2.27
3.2
2.8
9.15
5.28
e6/l
0.55
37
257
13
56
2.47
2.13
1.5
1.3
—
—
—
0
0
112
989
2.12
2.03
7.0
5.5
2.10
1.95
mu/l
0.25
106
893
38
251
1.73
2.00
4.9
5.2
—
—
—
0
0
113
1003
2.15
1.99
5.2
4.7
1.27
1.27
mmol/l
0.03
108
906
48
339
1.67
1.98
4.6
3.2
1.58
0.63
e6/l
0.30
35
244
51
367
1.65
1.96
3.5
3.3
—
—
—
0
0
118
1078
2.33
1.94
21.4
16.0
—
—
—
0
0
5
12
4.29
1.84
1.0
1.1
—
—
—
0
0
61
467
1.59
1.78
2.4
2.0
1.33
1.31
mmol/l
0.08
47
389
54
402
1.60
1.77
4.8
3.4
14.32
190.19
e6/l
0.56
41
307
59
454
1.56
1.66
5.8
4.1
71.51
55.92
e6/l
0.20
46
322
116
1057
2.13
1.61
6.5
5.5
4.42
4.51
mmol/l
0.43
111
972
115
1051
2.00
1.48
6.4
5.4
1.47
1.48
mmol/l
0.01
110
955
73
600
1.51
1.46
9.2
6.2
0.18
0.18
e9/l
0.25
62
523
28
185
1.66
1.45
8.5
8.0
104.61
103.95
mmol/l
0.26
28
185
17
97
1.87
1.43
1.5
2.5
—
—
—
0
0
71
584
1.49
1.39
8.7
6.0
0.61
0.60
e9/l
0.18
60
502
30
205
1.61
1.37
4.2
2.6
2.24
2.26
g/l
0.07
25
190
112
1021
1.82
1.36
8.2
7.1
41.39
40.25
mmol/mol
0.59
104
954
72
596
1.48
1.35
8.6
6.1
1.80
1.83
e9/l
0.08
63
526
71
587
1.48
1.33
8.7
6.0
0.04
0.04
e9/l
0.11
60
503
62
501
1.46
1.30
4.0
4.3
28.99
44.12
ng/l
0.96
43
382
114
1052
1.82
1.22
6.8
5.5
6.26
6.05
mmol/l
0.50
106
958
116
1076
1.90
1.22
7.1
6.3
2.50
2.58
mmol/l
0.46
111
989
18
111
1.72
1.20
12.9
11.4
—
—
—
0
0
53
422
1.44
1.17
4.3
4.0
—
—
—
0
0
48
380
1.42
1.08
10.2
5.8
—
—
—
0
0
12
68
1.84
1.04
1.8
1.6
—
—
—
0
0
14
84
1.75
1.03
5.6
4.3
—
—
—
0
0
48
384
1.40
1.01
7.4
4.4
7.40
7.39
ph
0.62
35
271
0
29
0.00
0.99
0.0
1.7
—
237.20
—
0
14
63
531
1.37
0.96
9.9
5.9
0.59
0.66
%
0.45
57
500
18
119
1.60
0.94
2.0
2.1
6.09
6.19
ph
0.13
11
80
19
128
1.57
0.92
3.3
3.3
63.14
70.59
e9/l
0.36
14
91
25
180
1.48
0.91
1.5
1.2
—
—
—
0
0
26
189
1.47
0.90
5.0
3.2
3.49
2.59
e6/l
0.15
13
93
63
535
1.35
0.90
9.8
5.8
2.74
2.72
%
0.03
57
505
63
537
1.34
0.87
9.8
5.9
9.29
8.94
%
0.28
56
508
37
290
1.39
0.86
1.8
1.3
—
—
—
0
0
17
116
1.54
0.79
2.4
2.0
80.83
168.37
ug/g
0.92
12
91
63
543
1.32
0.78
9.7
5.9
26.26
25.68
%
0.14
57
517
11
67
1.70
0.78
3.5
2.7
0.59
0.66
%
0.41
11
67
48
401
1.32
0.74
3.6
3.7
—
—
—
0
0
5
25
2.04
0.73
2.8
2.8
—
—
—
0
0
9
58
1.59
0.71
7.2
2.3
—
—
—
0
0
11
69
1.65
0.71
3.5
2.7
0.80
1.18
%
1.22
11
69
10
61
1.69
0.71
1.5
4.3
36.75
36.95
°c
—
10
61
50
423
1.30
0.70
6.7
5.8
3.24
1.99
ug/l
0.56
43
373
46
385
1.31
0.69
2.8
2.5
60.87
80.84
u/l
0.56
39
347
15
103
1.52
0.68
4.5
3.8
0.71
0.94
%
—
7
34
58
502
1.29
0.68
18.6
12.6
0.01
0.00
e9/l
0.48
46
394
11
70
1.63
0.67
3.4
2.4
1.42
1.59
g/l
0.23
11
62
46
387
1.30
0.66
1.9
1.8
23.68
21.51
nmol/l
0.28
35
326
93
858
1.31
0.64
31.5
23.3
14.01
13.89
%
0.29
88
848
14
98
1.48
0.59
4.3
4.3
0.00
0.04
%
—
5
25
32
261
1.30
0.57
1.7
1.9
379.60
458.64
pmol/l
1.30
25
225
13
91
1.48
0.55
4.4
4.0
1.83
0.50
%
—
6
26
19
147
1.34
0.49
1.5
1.8
—
—
—
0
0
18
139
1.34
0.47
5.2
4.1
7.38
7.38
ph
—
6
83
7
49
1.45
0.47
2.4
3.1
—
—
—
0
0
13
95
1.41
0.46
5.0
3.9
0.60
0.15
%
—
5
26
21
167
1.31
0.45
3.1
3.2
1.90
1.84
%
0.07
21
149
23
186
1.29
0.44
2.7
1.8
—
—
—
0
0
11
79
1.43
0.42
6.8
3.9
24.33
24.26
mmol/l
0.03
11
79
0
15
0.00
0.41
0.0
3.6
—
4.25
—
0
15
0
15
0.00
0.41
0.0
2.0
—
9.65
—
0
15
39
341
1.21
0.39
8.4
4.5
—
—
—
0
0
9
67
1.37
0.39
2.6
2.5
—
—
—
0
0
59
539
1.18
0.36
2.8
2.3
94.79
93.80
pmol/l
0.05
33
273
17
137
1.28
0.34
2.3
1.5
—
—
—
0
0
26
222
1.22
0.33
2.3
1.7
1146.83
1163.78
nmol/l
0.03
18
168
14
111
1.29
0.31
2.6
2.8
0.22
0.23
e6/l
0.02
14
104
17
140
1.25
0.29
1.2
1.3
—
—
—
0
0
8
67
1.21
0.27
1.4
1.4
—
—
—
0
0
5
74
0.66
0.26
1.2
1.1
—
—
—
0
0
5
75
0.65
0.26
1.0
1.2
—
—
—
0
0
14
114
1.26
0.26
2.1
1.7
—
—
—
0
0
9
72
1.27
0.26
1.6
1.4
—
—
—
0
0
9
73
1.25
0.26
1.4
1.6
0.95
1.09
g/l
—
9
63
65
610
1.13
0.25
22.0
14.4
1.30
1.29
inr
0.05
55
500
9
77
1.18
0.25
1.7
1.6
—
—
—
0
0
17
144
1.21
0.23
7.8
3.1
11.12
8.49
umol/l
0.22
17
128
8
100
0.79
0.22
2.3
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.8
—
0.82
—
0
11
0
11
0.00
0.21
0.0
1.0
—
314.67
—
0
6
0
11
0.00
0.21
0.0
2.0
—
423.00
—
0
6
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.21
0.20
1.3
1.7
3.13
0.53
ug/l
—
6
44
28
254
1.13
0.18
4.6
3.3
0.94
0.81
ug/l
0.29
17
162
28
256
1.12
0.16
3.9
4.3
1.02
1.02
kg/l
0.34
19
167
7
85
0.81
0.15
1.3
4.4
—
—
—
0
0
21
230
0.90
0.13
1.5
1.3
3.20
2.69
g/l
0.32
15
135
10
86
1.18
0.11
1.8
2.0
10.52
10.59
g/l
—
10
75
17
155
1.11
0.09
10.4
8.9
7.42
7.42
ph
—
6
83
11
97
1.15
0.09
2.7
3.4
121.91
194.76
ng/l
0.58
11
87
20
185
1.10
0.09
1.1
1.3
15.75
14.16
u/ml
0.04
11
76
8
75
1.07
0.07
1.5
1.3
—
—
—
0
0
27
256
1.07
0.07
2.3
1.6
1.17
1.40
mg/l
0.13
22
205
17
158
1.09
0.06
10.4
8.8
14.06
11.90
kpa
0.69
17
153
17
158
1.09
0.06
10.4
8.8
5.20
5.06
kpa
0.42
17
152
16
149
1.08
0.05
1.2
1.4
288.00
453.68
titre
—
5
38
12
110
1.10
0.05
22.3
7.7
11.78
10.44
mmol/l
0.28
12
105
14
150
0.93
0.04
1.4
4.7
49.90
38.54
ug/l
—
9
120
25
261
0.95
0.04
1.3
1.2
0.72
1.34
u/ml
—
6
80
20
208
0.95
0.02
1.2
1.3
21.50
38.52
iu/ml
—
5
65
36
362
0.99
0.00
8.8
6.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
140.20
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
2066.33
—
0
6
0
5
0.00
-0.00
0.0
2.4
—
78.60
—
0
5

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_MELANOMA_NOS – Melanoma in situ, other sites/unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).