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R14

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Chylothorax

Endpoint Browser PheWeb

J10_CHYLOTHORAX

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J94.0
  • Cause of death: ICD-10 — J94.0

2 out of 7 registries used, show all original rules.

90

4. Check minimum number of events

None

90

5. Include endpoints

None

90

6. Filter based on genotype QC (FinnGen only)

78

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 78 33 45
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 64.67 58.68 69.07

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
82
Matched controls
820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J94.0
ICD-10 Finland
Chylous effusion
+∞
118.0
82
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
56.3
23.5
27
7
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
32.9
23.0
30
14
J94.8
ICD-10 Finland
Other specified pleural conditions
50.3
21.3
25
7
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
50.3
21.3
25
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.3
15.6
41
112
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
152.3
12.8
13
*
C03CA01
ATC
furosemide; systemic
4.7
11.1
49
196
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.3
10.5
63
314
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
14.9
9.9
16
13
J94.9
ICD-10 Finland
Pleural condition, unspecified
112.5
9.6
10
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
112.5
9.6
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.9
9.1
19
40
A04AA01
ATC
ondansetron; systemic, rectal
5.7
8.9
19
41
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
9.3
8.7
18
24
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.8
8.6
18
38
R4190
NOMESCO Finland
Nutritional therapy
5.8
8.6
18
38
JN4AD
NOMESCO Finland
Body CT examination
4.5
7.7
23
66
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
12.6
7.6
13
12
R06.0
ICD-10 Finland
Dyspnoea
3.6
7.4
39
166
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
+∞
7.4
7
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.6
6.9
31
118
TGA30
NOMESCO Finland
Thoracocentesis
43.8
6.9
8
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
7.7
6.7
15
23
GD1AD
NOMESCO Finland
Thorax CT examination
6.8
6.6
16
28
L03AA13
ATC
pegfilgrastim; parenteral
8.4
6.2
13
18
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.4
6.1
29
113

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
25
5
70.66
22.65
2.0
2.0
—
—
—
0
0
19
7
34.70
15.08
1.8
1.7
—
—
—
0
0
19
9
26.91
14.12
2.2
2.0
—
—
—
0
0
13
0
+∞
13.94
1.5
0.0
1.75
—
mmol/l
—
13
0
26
54
6.59
12.95
4.3
2.3
408.42
183.42
ng/l
0.88
26
48
42
137
5.23
12.63
3.0
2.0
—
—
—
0
0
69
362
6.72
10.97
20.1
14.2
1.33
1.28
inr
0.30
58
306
51
226
4.32
9.69
7.3
4.6
—
—
—
0
0
28
92
4.10
7.82
12.7
9.5
1.63
1.00
mmol/l
0.29
23
76
27
92
3.88
7.10
13.1
9.5
7.38
7.42
ph
1.13
16
45
35
147
3.41
6.66
4.7
3.8
801.03
524.67
ng/l
0.26
29
117
26
91
3.72
6.52
4.3
7.0
8.19
7.57
umol/l
0.08
21
80
31
124
3.41
6.33
12.4
9.5
103.84
104.18
mmol/l
0.18
31
124
69
458
4.20
5.88
12.0
6.2
6.85
6.69
mmol/l
0.28
69
437
26
97
3.46
5.87
15.2
12.9
—
—
—
0
0
28
112
3.28
5.64
4.9
7.9
7.38
7.39
ph
0.16
16
71
63
404
3.41
5.47
17.6
8.9
1.18
1.21
mmol/l
2.28
54
355
28
115
3.18
5.37
4.9
7.8
6.06
5.54
kpa
1.30
28
110
16
45
4.18
5.36
9.4
3.8
—
—
—
0
0
46
250
2.91
5.34
5.6
2.9
—
—
—
0
0
9
10
9.93
4.92
1.8
2.9
25.73
40.24
%
—
9
10
19
66
3.45
4.71
6.1
5.3
0.60
0.93
%
—
10
27
24
100
2.98
4.41
1.7
1.5
—
—
—
0
0
18
63
3.38
4.40
6.0
5.3
0.13
0.12
%
—
8
24
20
77
3.11
4.19
26.0
15.0
25.70
24.79
mmol/l
0.39
20
77
8
10
8.71
4.16
1.9
3.2
24.38
6.80
%
—
8
10
10
19
5.83
3.97
1.3
1.5
—
—
—
0
0
10
19
5.83
3.97
1.3
1.5
—
—
—
0
0
10
19
5.83
3.97
1.3
1.5
—
—
—
0
0
10
19
5.83
3.97
1.3
1.5
—
—
—
0
0
8
11
7.91
3.96
1.6
6.2
—
—
—
0
0
6
5
12.79
3.82
1.2
1.2
—
—
—
0
0
35
189
2.49
3.82
2.7
3.1
4.29
5.09
e6/l
0.23
30
169
30
152
2.54
3.73
7.8
6.2
—
—
—
0
0
45
275
2.41
3.72
11.7
7.1
—
—
—
0
0
19
76
2.95
3.70
5.9
9.4
23.84
23.52
mmol/l
0.14
19
76
17
64
3.09
3.67
6.1
5.3
0.33
0.58
%
—
9
25
8
13
6.69
3.59
2.0
1.5
—
—
—
0
0
58
404
2.49
3.48
12.3
7.3
0.04
0.04
e9/l
0.03
52
334
8
14
6.20
3.43
1.8
2.7
16.11
16.08
%
—
8
14
50
329
2.33
3.38
5.4
3.1
—
—
estimate
—
0
0
31
166
2.39
3.38
3.5
2.7
1.61
1.06
mg/l
0.70
26
132
58
408
2.44
3.35
12.4
7.3
1.49
1.97
e9/l
2.74
52
354
46
296
2.26
3.23
5.3
4.6
73.19
38.23
e6/l
0.34
38
213
38
226
2.27
3.23
7.9
4.5
7.40
7.39
ph
1.01
27
167
17
69
2.85
3.21
3.5
1.6
1.35
1.34
g/l
0.02
17
64
58
413
2.38
3.18
13.6
7.7
0.18
0.21
e9/l
0.41
53
352
16
64
2.86
3.10
5.9
5.8
0.00
0.35
%
—
5
23
43
273
2.21
3.08
3.8
3.9
19.06
35.05
e6/l
0.49
37
212
13
47
3.10
2.98
3.6
4.1
—
—
—
0
0
36
216
2.19
2.94
3.5
3.9
—
—
estimate
—
0
0
56
403
2.23
2.85
12.6
7.3
0.72
0.59
e9/l
2.32
51
336
5
6
8.77
2.78
1.2
1.2
6.26
5.22
mg/l
—
5
6
21
102
2.42
2.78
3.1
7.1
4.34
4.83
kpa
0.62
21
97
6
10
6.37
2.75
2.3
3.3
13.80
18.76
ug/l
—
6
10
14
56
2.81
2.70
2.4
5.8
0.50
0.62
%
0.92
14
56
14
57
2.76
2.61
2.4
5.7
1.19
1.21
%
0.03
14
57
37
233
2.07
2.60
3.9
4.0
0.30
0.47
e6/l
0.48
30
175
12
45
2.95
2.58
10.8
4.9
36.94
36.91
°c
0.12
12
45
6
12
5.30
2.45
2.0
1.3
—
—
—
0
0
6
12
5.30
2.45
16.5
2.4
—
—
—
0
0
5
8
6.56
2.40
2.8
2.3
0.68
0.84
nmol/l
—
5
8
25
140
2.13
2.35
3.6
3.0
2.46
2.47
mmol/l
0.11
25
125
31
189
2.03
2.33
1.4
1.4
—
—
—
0
0
20
104
2.22
2.25
2.0
1.7
—
—
—
0
0
5
9
5.83
2.24
1.4
3.4
19.60
25.44
%
—
5
9
41
282
1.91
2.15
2.6
2.1
1.28
1.23
mmol/l
0.17
36
232
5
11
4.76
1.97
1.4
3.4
23.20
17.18
%
—
5
11
14
67
2.31
1.89
19.3
6.4
—
—
—
0
0
6
17
3.72
1.87
1.7
1.7
125.17
125.90
g/l
—
6
10
9
35
2.76
1.86
1.2
1.3
—
—
—
0
0
21
121
1.99
1.80
1.4
2.1
—
—
—
0
0
15
79
2.10
1.62
1.2
1.6
—
—
—
0
0
7
27
2.74
1.55
1.0
1.7
—
—
—
0
0
28
186
1.77
1.55
2.1
1.5
2.18
2.42
g/l
0.19
22
109
6
22
2.86
1.46
1.7
1.8
—
—
—
0
0
6
22
2.86
1.46
1.2
1.3
—
—
—
0
0
35
252
1.68
1.44
19.7
7.2
—
—
—
0
0
6
23
2.73
1.39
1.5
2.0
—
—
—
0
0
32
229
1.65
1.33
1.6
1.8
17.91
21.31
nmol/l
0.58
27
190
12
63
2.06
1.31
2.7
2.4
—
—
—
0
0
5
18
2.89
1.30
1.8
1.9
18.00
17.44
ng/l
—
5
18
8
36
2.35
1.28
1.1
1.3
—
—
—
0
0
46
363
1.61
1.28
24.1
12.5
0.00
0.01
e9/l
0.50
41
283
12
64
2.02
1.26
1.5
1.4
—
—
—
0
0
30
221
1.56
1.07
2.8
4.1
0.00
0.00
estimate
-0.00
11
69
69
616
1.76
1.04
5.7
5.5
1.96
1.96
mu/l
0.01
62
562
48
396
1.51
1.01
4.0
4.1
0.00
0.00
estimate
-0.00
14
78
49
408
1.50
0.97
4.2
4.1
0.00
0.00
estimate
-0.00
12
73
34
266
1.48
0.90
4.1
4.0
—
—
—
0
0
75
697
1.89
0.86
34.7
15.3
—
—
—
0
0
15
98
1.65
0.86
1.6
1.6
—
—
—
0
0
34
271
1.43
0.80
4.1
3.6
6.66
7.83
mmol/l
0.94
29
223
19
135
1.53
0.78
3.7
3.8
2.00
2.28
e6/l
0.10
14
76
47
399
1.42
0.78
4.2
4.1
0.00
0.00
estimate
-0.00
12
79
59
527
1.43
0.69
5.3
4.4
15.27
14.83
pmol/l
0.46
54
476
15
105
1.52
0.66
1.3
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
5
89
0.53
0.60
1.0
1.5
—
—
—
0
0
39
332
1.33
0.58
2.4
2.2
90.10
94.00
pmol/l
0.26
26
175
36
309
1.29
0.49
3.9
4.0
6.42
6.30
ph
0.21
18
179
30
252
1.30
0.48
4.6
3.4
35.55
87.20
mg/l
1.62
25
168
26
214
1.31
0.48
3.5
3.6
0.00
0.00
estimate
—
8
60
10
69
1.51
0.47
3.9
5.7
67.25
91.45
ng/l
—
10
59
27
226
1.29
0.44
2.7
3.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
18
221
0.76
0.40
2.8
3.3
—
—
—
0
0
60
638
0.78
0.38
5.9
6.4
2.30
2.58
mmol/l
1.79
52
587
30
260
1.24
0.36
5.0
4.0
7.41
12.84
mg/mmol
0.66
22
166
58
616
0.80
0.34
7.6
7.3
40.46
40.15
mmol/mol
0.08
51
572
59
625
0.80
0.33
5.0
5.4
1.25
1.44
mmol/l
2.29
53
569
59
553
1.24
0.32
65.2
24.6
327.02
332.92
g/l
4.96
59
553
14
113
1.29
0.29
1.7
1.6
—
—
—
0
0
20
170
1.23
0.28
3.5
4.4
1.02
1.02
kg/l
0.61
15
118
5
74
0.65
0.27
1.6
1.2
—
—
—
0
0
5
39
1.30
0.23
1.0
1.3
—
—
—
0
0
33
300
1.17
0.23
3.5
4.1
0.00
0.02
estimate
—
9
63
27
299
0.86
0.22
4.4
6.0
1.63
3.05
ug/l
0.71
21
269
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
4.6
—
344.00
—
0
10
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.5
—
10.00
—
0
12
6
48
1.27
0.21
1.2
2.2
—
—
—
0
0
15
174
0.83
0.20
2.9
3.2
0.62
0.72
ug/l
—
10
126
30
274
1.15
0.19
2.2
2.3
—
—
—
0
0
6
71
0.83
0.08
1.7
1.8
—
—
—
0
0
8
94
0.84
0.07
2.3
2.7
224.38
144.71
ug/g
—
8
77
64
628
1.09
0.06
4.7
5.4
6.09
6.08
mmol/l
0.02
58
573
62
629
0.94
0.03
5.2
5.5
3.94
4.45
mmol/l
3.22
54
575
19
195
0.97
0.00
1.5
1.5
0.63
1.85
u/ml
—
7
46
60
605
0.97
0.00
4.8
4.6
1.30
1.27
mmol/l
0.19
53
550
10
96
1.05
0.00
1.3
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
8.54
—
0
8
7
69
1.02
0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.1
—
1.85
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
11.2
—
0.61
—
0
6
0
5
0.00
-0.00
0.0
3.4
—
1.74
—
0
5
6
64
0.93
-0.00
1.8
3.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
49.5
—
132.00
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
46.04
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
0.61
—
0
5
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: J10_CHYLOTHORAX – Chylothorax

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).