preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
504 |
4. Check minimum number of eventsNone |
504 |
5. Include endpointsNone |
504 |
6. Filter based on genotype QC (FinnGen only) |
468 |
Control definitions (FinnGen only)
- Control exclude
- O15_OEDEM_PROTUR_HYPERT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O10-O16
- Name in latin
- Hypertensio graviditatis non specificata
Similar endpoints
↥List of similar endpoints to
Unspecified maternal hypertension
based on the number of shared cases.
Similar with more cases:
- Pregnancy hypertension
- Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
- Pregnancy, childbirth and the puerperium
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2797 | 2797 | - |
| Only index persons | 2780 | 2780 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | - |
| Only index persons | 0.10 | 0.10 | - |
| Median age at first event (years) | |||
| Whole population | - | 30.63 | - |
| Only index persons | - | 30.63 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 468 | 468 | - |
| Unadjusted period prevalence (%) | 0.17 | 0.17 | - |
| Median age at first event (years) | 31.30 | 31.30 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 479
- Matched controls
- 4790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O16
ICD-10 Finland
Unspecified maternal hypertension
+∞
307.7
440
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1806.7
232.4
207
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
+∞
80.5
75
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
+∞
67.3
63
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
5.3
61.2
162
420
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
4.6
55.8
192
609
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
504.6
47.2
46
*
C09AA02
ATC
enalapril; systemic
6.9
44.7
76
128
I10
ICD-10 Finland
Essential (primary) hypertension
3.5
39.1
212
884
6429A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Unspecified hypertension complicating pregnancy, childbirth, or the puerperium[HYPERTENSIO GRAVIDARUM NUD,ENNEN SYNNYTYSTÄ]
+∞
35.9
34
*
C07AG01
ATC
labetalol; systemic
45.9
34.6
42
10
O14.1
ICD-10 Finland
Severe pre-eclampsia
+∞
33.7
32
*
205
Kela drug reimbursment
Chronic hypertension
6.2
32.8
60
108
C08CA05
ATC
nifedipine; systemic
7.9
31.5
45
62
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
8.9
30.4
39
47
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.0
28.1
328
2005
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.2
27.1
145
580
SPAT1324
SPAT
Screening procedure
2.7
25.1
215
1101
W84
ICPC
Pregnancy high risk
3.9
23.3
77
225
C08CA01
ATC
amlodipine; oral
3.1
22.5
111
419
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.8
22.3
154
699
C09CA01
ATC
losartan; oral
3.3
21.5
93
324
OAA41, ,
SPAT
4.4
19.5
52
129
OAB47, ,
SPAT
3.3
19.5
86
302
LX2A3, ,
SPAT
3.7
18.2
62
184
MAC96
NOMESCO Finland
Other induction or advancement of labour
4.1
18.0
53
142
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
4.5
17.8
45
107
ZXD05
NOMESCO Finland
Urgent procedure
2.3
17.1
207
1192
E66.9
ICD-10 Finland
Obesity, unspecified
4.1
15.6
44
114
C07AB02
ATC
metoprolol; systemic
3.2
15.5
67
231
OAA11, ,
SPAT
2.7
15.3
94
395
SPAT1357
SPAT
Monitoring of problem during pregnancy
3.8
15.2
48
135
SPAT1210
SPAT
Application of cast or individual aid
5.0
14.9
33
70
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.6
13.3
85
362
K85
ICPC
Elevated blood pressure
3.1
12.9
58
204
OAA12, ,
SPAT
2.8
12.9
72
286
C09CA06
ATC
candesartan; oral
2.3
12.8
123
631
OAA10, ,
SPAT
2.8
12.6
70
278
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
6.1
11.9
21
36
C07AB07
ATC
bisoprolol; oral
2.1
11.5
144
816
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
10.8
222
1489
C09DA01
ATC
losartan and diuretics; oral
3.8
10.7
33
91
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3.3
10.4
40
128
WX234
NOMESCO Finland
Paracervical blockade
3.0
10.1
48
174
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.1
9.7
42
145
SPAT1373
SPAT
Combined screening in early pregnancy
3.7
9.5
30
84
C08CA13
ATC
lercanidipine; oral
3.2
9.5
38
125
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
9.4
116
648
6424A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, ENNEN SYNNYTYSTÄ]
+∞
9.4
9
*
6423A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Transient hypertension of pregnancy[HYPERTENSIO GRAVIDARUM, ENNEN SYNNYTYSTÄ]
+∞
9.4
9
*
O10.9
ICD-10 Finland
Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
+∞
9.4
9
*
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.5
9.4
61
261
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.0
9.2
131
771
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.3
9.1
35
112
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
3.3
9.1
35
112
O32.1
ICD-10 Finland
Maternal care for breech presentation
2.5
9.1
58
246
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
8.8
175
1143
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.6
8.6
21
33
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.6
8.3
28
82
W78
ICPC
Pregnancy
1.8
8.3
188
1272
ZXH09, ,
SPAT
3.8
8.3
25
68
C09CA07
ATC
telmisartan; oral
4.1
8.2
22
55
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
3.6
7.9
26
75
SPAT1379
SPAT
Health check-up of pregnant person
1.9
7.9
135
837
E66.01
ICD-10 Finland
Obesity due to excess calories
2.1
7.9
82
429
SPAT1263
SPAT
Sampling
1.7
7.9
211
1495
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.9
7.8
37
134
OAB30, ,
SPAT
3.7
7.8
25
71
O60
ICD-10 Finland
Preterm labour and delivery
2.9
7.6
35
125
SPAT1316
SPAT
Extensive health check-up of children and adolescents
2.8
7.5
37
137
SPAT1301
SPAT
No procedures
1.8
7.5
139
884
O12.1
ICD-10 Finland
Gestational proteinuria
81.3
7.4
8
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.7
7.3
276
2132
SPAT1196
SPAT
Monitoring of normal pregnancy
2.0
7.3
87
478
MA3AE
NOMESCO Finland
Combined first trimester screening
2.1
7.3
77
405
SPAT1189
SPAT
Other ultrasound examination during pregnancy
2.6
7.2
41
164
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.1
7.2
78
413
O12.0
ICD-10 Finland
Gestational oedema
20.4
7.2
10
5
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.1
7.0
75
395
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.8
6.8
18
32
R03.0
ICD-10 Finland
Elevated blood-pressure reading, without diagnosis of hypertension
2.9
6.6
31
112
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.0
6.6
29
101
SPAT1312
SPAT
General health counselling
1.7
6.4
165
1142
SPAT1260
SPAT
Consultation of another employee
2.0
6.4
76
417
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.0
6.4
76
417
J01DA01
ATC
[U] cefalexin
1.7
6.3
305
2466
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.8
6.3
19
52
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.2
6.2
52
249
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.6
6.1
182
1303
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.0
6.1
67
357
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
5.7
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
146
348
5.60
60.70
1.7
1.4
—
—
—
0
0
129
317
5.20
51.07
5.0
3.9
—
—
—
0
0
158
680
2.97
25.78
3.6
3.9
13.24
5.70
mg/mmol
1.23
123
413
199
1011
2.66
23.18
4.8
3.0
1.02
1.02
kg/l
1.06
107
647
182
918
2.58
21.14
3.3
3.0
7.53
8.07
mmol/l
0.79
177
815
47
123
4.13
16.42
5.1
10.0
93.23
94.87
%
0.63
47
123
119
548
2.56
16.13
1.7
1.4
—
—
—
0
0
152
805
2.30
14.97
2.3
1.9
300.95
287.93
umol/l
1.25
146
753
199
1216
2.09
13.37
4.8
3.2
0.00
0.01
estimate
1.08
36
467
194
1198
2.04
12.47
3.6
2.8
—
—
—
0
0
147
821
2.14
12.35
1.6
1.6
812.35
1049.08
mu/l
3.40
121
674
315
2316
2.05
12.28
4.6
3.1
0.00
0.00
estimate
0.50
38
481
318
2349
2.05
12.20
4.7
3.2
0.03
6.11
estimate
0.80
38
477
67
266
2.77
12.01
2.2
2.4
80.95
84.92
ml/min/173m2
0.42
19
104
72
302
2.63
11.59
5.4
5.8
105.60
105.23
mmol/l
0.37
72
302
59
227
2.82
11.20
5.9
9.7
0.21
0.72
mmol/l
0.43
41
167
313
2354
1.95
10.72
4.8
3.2
0.00
0.02
estimate
1.06
38
470
34
101
3.55
9.92
2.2
1.8
0.68
0.60
%
0.82
34
101
34
102
3.51
9.77
2.2
1.9
1.54
1.54
%
0.00
34
102
251
1806
1.82
9.35
4.1
2.9
0.07
0.05
estimate
0.07
30
412
34
123
2.90
7.22
2.4
2.2
4.02
3.44
g/l
1.87
34
117
154
1027
1.74
6.94
1.9
1.7
1.07
0.75
mg/l
1.33
125
771
424
3745
2.15
6.81
5.3
5.0
14.45
14.15
pmol/l
2.26
413
3593
76
411
2.01
6.62
1.8
1.9
27.31
29.02
s
3.33
76
400
50
229
2.32
6.62
1.3
1.3
—
—
—
0
0
264
2048
1.64
6.58
5.0
4.1
6.29
6.15
mmol/l
0.57
236
1847
84
473
1.94
6.52
1.4
1.5
1.40
1.21
ratio
0.64
48
290
84
473
1.94
6.52
1.4
1.5
0.96
0.97
ratio
0.05
48
289
64
329
2.09
6.39
2.2
1.8
—
—
—
0
0
82
462
1.93
6.35
1.4
1.5
—
—
—
0
0
455
4164
2.85
6.33
6.1
5.8
1.63
1.68
mu/l
0.51
448
4050
83
473
1.91
6.21
1.4
1.5
1.06
1.15
ratio
0.53
47
289
56
279
2.14
6.06
1.5
1.5
48.16
59.81
ug/l
1.68
56
279
43
192
2.36
6.03
1.2
1.4
20.27
20.36
u/l
0.01
38
160
113
717
1.75
5.96
2.4
2.3
7.72
10.30
e6/l
0.86
103
650
194
1431
1.60
5.69
3.7
4.1
36.24
37.67
g/l
2.62
188
1368
31
123
2.63
5.57
2.1
1.4
307.97
336.69
mu/l
0.19
31
104
84
497
1.84
5.57
1.4
1.6
52.42
62.19
ug/l
1.86
72
410
52
262
2.10
5.47
1.3
1.4
—
—
—
0
0
146
1018
1.62
5.34
1.8
1.9
—
—
—
0
0
65
374
1.85
4.70
1.8
1.6
—
—
—
0
0
95
615
1.68
4.58
2.8
2.2
13114.23
5888.05
u/l
0.73
35
252
30
130
2.40
4.53
1.9
2.8
126.83
134.93
g/l
0.97
30
125
35
165
2.21
4.37
2.8
2.1
3.88
4.65
umol/l
0.39
25
122
87
558
1.68
4.33
2.9
2.3
1.72
0.96
e6/l
0.72
53
262
145
1064
1.52
4.09
2.9
2.5
75.16
19.31
ng/l
0.38
56
388
9
14
6.53
4.00
3.8
1.9
1377.78
673.86
mg
—
9
14
253
2098
1.44
3.73
2.9
2.6
—
—
estimate
—
0
0
417
3828
1.69
3.67
3.8
3.2
1.25
1.15
mmol/l
2.27
409
3688
418
3844
1.69
3.60
4.1
3.6
5.52
5.51
mmol/l
0.17
405
3683
34
176
2.00
3.38
2.4
1.9
4.75
4.96
kpa
0.24
34
170
39
212
1.91
3.38
5.4
5.9
1.28
1.21
mmol/l
0.21
39
206
36
191
1.96
3.35
3.2
6.8
5.29
6.38
mmol/l
0.77
36
186
151
1160
1.44
3.29
2.8
2.5
53.72
58.97
u/l
0.75
142
1093
193
1551
1.41
3.26
1.9
1.7
—
—
—
0
0
13
44
3.01
3.16
1.4
1.2
—
—
—
0
0
125
934
1.46
3.13
3.1
2.5
0.25
0.31
e6/l
0.30
96
658
452
4283
1.98
3.08
12.0
10.5
19.01
17.74
mg/l
0.43
376
3387
436
4091
1.73
3.01
4.3
3.7
4.77
4.81
mmol/l
0.36
430
3984
9
21
4.35
3.01
1.4
1.2
—
—
—
0
0
5
5
10.09
2.98
1.0
1.2
—
—
—
0
0
111
822
1.46
2.90
2.3
1.8
—
—
—
0
0
194
1589
1.37
2.83
1.7
1.6
—
—
—
0
0
396
3649
1.49
2.79
4.7
4.1
36.76
36.46
mmol/mol
0.35
390
3532
130
998
1.42
2.79
2.9
2.0
—
—
—
0
0
33
182
1.87
2.77
1.6
2.2
65.98
68.20
g/l
1.18
33
171
434
4083
1.67
2.76
4.2
3.7
1.46
1.54
mmol/l
5.25
426
3959
436
4115
1.66
2.63
4.7
3.9
2.91
2.87
mmol/l
0.53
431
3989
0
69
0.00
2.62
0.0
1.4
—
—
—
0
0
37
216
1.77
2.61
2.7
2.7
5.49
5.77
kpa
1.24
37
207
9
25
3.65
2.58
4.1
3.1
809.33
459.04
u/ml
—
9
25
166
1347
1.36
2.51
4.9
4.8
1.19
1.21
mmol/l
4.96
161
1261
15
64
2.39
2.41
1.1
1.6
—
—
—
0
0
51
335
1.58
2.34
1.4
1.5
—
—
—
0
0
417
3922
1.49
2.25
7.6
8.4
94.88
95.36
ml/min/173m2
0.22
381
3501
363
3871
0.74
2.01
13.1
12.6
13.38
13.27
%
1.18
358
3831
22
120
1.87
1.96
1.1
1.4
3.45
3.53
mmol/l
0.20
22
114
7
173
0.40
1.94
1.1
1.3
—
2.45
—
0
13
6
17
3.56
1.84
1.0
1.1
—
—
—
0
0
42
281
1.54
1.81
1.3
1.6
—
—
—
0
0
217
1892
1.27
1.81
5.1
5.1
8.82
9.50
umol/l
0.74
207
1808
9
35
2.60
1.81
1.2
1.4
—
—
—
0
0
14
67
2.12
1.77
2.9
1.9
0.83
1.21
ug/l
0.30
14
58
8
30
2.69
1.73
1.5
1.8
83.92
101.74
nmol/24h
—
8
30
27
164
1.68
1.72
1.0
1.1
5.56
4.67
—
5
31
27
165
1.67
1.68
2.2
1.5
—
—
—
0
0
33
213
1.59
1.67
1.2
1.7
—
—
—
0
0
16
83
1.96
1.66
1.6
1.5
28.54
31.23
nmol/l
0.20
16
67
32
206
1.59
1.64
1.1
1.1
2.87
2.88
u/ml
0.00
16
100
8
174
0.45
1.61
1.0
1.3
—
21.01
—
0
33
5
125
0.39
1.52
3.0
1.9
—
—
—
0
0
15
266
0.55
1.49
3.3
2.5
—
—
—
0
0
119
1418
0.79
1.48
2.5
2.5
0.00
0.15
estimate
0.66
33
406
335
3120
1.25
1.40
3.6
3.8
8.77
8.48
mm/h
0.26
321
2992
131
1533
0.80
1.38
1.8
1.8
98.87
98.42
pmol/l
0.05
86
881
45
326
1.42
1.36
3.3
5.2
1.01
1.04
mmol/l
0.36
45
296
28
187
1.53
1.27
2.2
2.6
2.08
4.84
iu/l
2.99
14
86
16
94
1.73
1.19
1.0
1.1
—
—
—
0
0
8
39
2.07
1.15
1.4
1.5
—
—
—
0
0
5
20
2.52
1.15
1.2
1.6
—
—
—
0
0
16
96
1.69
1.11
1.6
1.5
—
—
—
0
0
17
104
1.66
1.11
1.1
1.1
—
—
—
0
0
7
31
2.28
1.10
1.4
1.2
—
—
—
0
0
7
34
2.07
1.03
1.0
1.1
2964.14
1601.18
miu/ml
—
7
34
16
99
1.64
1.01
1.1
1.1
2.00
1.65
u/ml
—
5
37
11
187
0.58
0.99
1.1
1.3
—
22.08
—
0
9
5
23
2.19
0.98
1.0
1.2
46.60
81.74
ug/l
—
5
23
5
23
2.19
0.98
3.8
2.9
21.80
14.17
%
—
5
23
174
1561
1.18
0.97
4.6
5.4
1.20
1.21
mmol/l
2.31
164
1372
264
2453
1.17
0.94
6.4
8.3
4.25
3.96
e9/l
1.43
237
2170
15
94
1.62
0.91
2.2
3.0
1.47
1.20
mg/l
0.93
15
87
23
161
1.45
0.88
1.1
1.0
1.64
4.11
u/ml
0.88
15
67
309
2925
1.16
0.81
6.2
6.5
71.57
71.80
u/l
0.05
299
2801
16
235
0.67
0.81
1.5
1.9
—
—
—
0
0
53
645
0.80
0.80
1.3
1.6
3.65
3.36
mmol/l
1.04
32
430
44
350
1.28
0.79
1.5
1.4
239.02
234.17
miu/ml
0.03
22
194
0
26
0.00
0.78
0.0
1.9
—
—
—
0
0
127
1130
1.17
0.77
2.3
2.0
2.87
2.39
mg/l
2.16
122
988
21
150
1.42
0.74
4.3
6.5
23.95
24.63
mmol/l
0.55
21
150
13
195
0.66
0.74
1.5
2.8
1.21
1.23
mmol/l
1.05
13
166
7
38
1.85
0.74
1.1
1.1
95.71
113.95
pmol/l
—
7
38
37
291
1.29
0.73
1.4
1.6
—
—
—
0
0
19
134
1.44
0.72
1.1
1.2
—
—
—
0
0
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
10
153
0.65
0.63
1.1
1.3
—
60.09
—
0
12
8
51
1.58
0.60
1.0
1.1
158.25
214.53
mg/l
—
8
43
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
23
176
1.32
0.57
1.1
1.1
0.83
1.67
u/ml
0.61
12
78
138
1503
0.89
0.57
3.4
3.0
29.18
25.86
u/l
1.13
138
1449
16
115
1.40
0.57
5.1
2.6
10.21
10.01
mg/l
0.05
16
107
71
809
0.86
0.56
1.5
1.7
3.53
3.22
ratio
1.02
45
591
12
82
1.48
0.55
1.2
1.4
1.05
1.83
nmol/l
1.75
12
75
9
60
1.51
0.54
1.0
1.2
—
—
—
0
0
184
1961
0.90
0.51
2.2
2.4
74.50
73.64
nmol/l
0.17
179
1880
9
64
1.41
0.51
1.7
1.7
6.13
7.43
mmol/l
—
9
64
25
313
0.79
0.51
1.1
1.1
0.89
0.84
g/l
0.64
25
313
18
136
1.34
0.50
1.1
1.2
—
—
—
0
0
43
364
1.20
0.49
1.4
1.6
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
14
102
1.38
0.48
1.2
1.2
8.38
5.36
u/ml
—
8
39
7
48
1.46
0.47
1.4
1.3
—
—
—
0
0
16
120
1.34
0.46
1.3
1.2
—
—
—
0
0
14
187
0.74
0.46
1.6
2.0
1.36
1.19
g/l
1.34
14
177
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
29
238
1.23
0.45
1.1
1.3
0.36
2.55
u/ml
—
5
12
7
50
1.41
0.45
1.1
1.9
5.96
9.13
u/ml
—
7
50
50
434
1.17
0.44
1.5
1.7
—
—
—
0
0
31
370
0.83
0.43
1.0
1.1
—
—
—
0
0
32
380
0.83
0.42
2.5
2.6
26.72
35.57
u/l
1.26
32
317
56
494
1.15
0.41
3.9
2.5
273.63
516.43
ng/l
0.78
49
394
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
8
59
1.36
0.41
1.7
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
30.83
—
0
17
0
17
0.00
0.40
0.0
1.2
—
94.94
—
0
17
0
18
0.00
0.40
0.0
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
26
311
0.83
0.38
1.1
1.1
1.47
1.61
g/l
3.16
26
311
317
3262
0.92
0.38
2.8
3.0
34.37
30.60
u/l
0.69
307
3182
135
1263
1.10
0.38
2.0
2.1
—
—
—
0
0
63
565
1.13
0.37
1.2
1.3
134.68
152.65
u/ml
0.19
36
240
5
37
1.35
0.37
1.0
1.1
17.80
7.65
mm/h
—
5
37
24
198
1.22
0.37
1.3
1.3
—
—
—
0
0
18
222
0.80
0.35
1.8
1.5
0.32
0.30
mg/l
—
9
87
18
221
0.81
0.34
2.3
2.2
—
—
—
0
0
134
1423
0.92
0.34
1.2
1.3
0.61
1.64
u/ml
1.80
40
406
6
45
1.34
0.34
1.2
1.4
18.60
17.59
%
—
6
45
23
274
0.83
0.33
2.0
2.3
0.23
0.23
g/l
0.09
23
261
14
176
0.79
0.32
1.6
2.0
0.24
0.23
g/l
0.13
14
167
17
137
1.25
0.32
1.1
1.1
0.35
0.10
u/ml
—
5
36
393
3865
1.09
0.29
4.1
4.1
—
—
—
0
0
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
8
62
1.30
0.28
1.9
1.7
5.67
6.04
pmol/l
—
8
62
9
119
0.75
0.27
1.6
1.6
—
—
—
0
0
147
1401
1.07
0.26
2.2
2.3
—
—
—
0
0
5
72
0.69
0.26
1.4
1.5
—
—
—
0
0
18
213
0.84
0.25
2.9
4.1
1.71
30.57
ug/l
0.64
13
151
68
629
1.09
0.25
1.4
1.6
1.27
1.31
%
0.26
63
578
5
38
1.32
0.23
1.2
1.2
—
—
—
0
0
11
88
1.26
0.22
1.9
1.9
—
—
—
0
0
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
13
107
1.22
0.22
1.2
1.3
—
—
—
0
0
25
220
1.14
0.21
1.7
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
39.29
—
0
11
0
11
0.00
0.21
0.0
2.9
—
3.37
—
0
6
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
3.1
—
2.01
—
0
8
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
20
228
0.87
0.19
2.4
3.3
59.56
63.69
ng/l
0.23
20
212
12
100
1.21
0.18
1.2
1.3
100.43
221.59
u/ml
—
7
69
7
61
1.15
0.17
1.0
1.1
—
—
—
0
0
7
63
1.11
0.17
1.0
1.1
—
—
—
0
0
5
67
0.74
0.17
1.4
1.4
—
—
—
0
0
103
989
1.05
0.15
1.4
1.3
6.20
10.96
u/ml
0.44
58
431
6
80
0.75
0.15
1.3
1.4
—
—
—
0
0
35
378
0.92
0.15
2.3
2.3
16.75
21.54
au/ml
—
6
56
55
524
1.06
0.11
3.2
2.4
8.73
5.49
e6/l
0.41
22
231
5
45
1.11
0.10
1.2
1.4
—
—
—
0
0
5
45
1.11
0.10
1.2
1.4
—
—
—
0
0
5
47
1.06
0.09
1.6
2.4
—
—
—
0
0
13
116
1.12
0.09
3.0
2.5
41.92
71.19
ng/l
1.45
13
105
6
56
1.07
0.08
1.2
1.1
—
—
—
0
0
156
1589
0.97
0.08
1.6
1.8
1.40
1.30
mmol/l
1.04
148
1454
6
73
0.82
0.07
1.2
1.3
—
—
—
0
0
7
85
0.82
0.07
1.3
1.4
—
—
—
0
0
19
201
0.94
0.04
1.4
1.7
—
—
—
0
0
55
537
1.03
0.04
3.1
2.6
770.23
445.61
ng/l
0.16
30
227
110
1085
1.02
0.04
1.4
1.4
18.12
20.19
iu/ml
0.14
28
307
34
349
0.97
0.02
1.2
1.3
—
23.66
—
0
22
11
107
1.03
0.00
2.7
2.0
12.95
13.22
%
0.48
11
107
24
236
1.02
0.00
1.3
2.3
1.39
8.40
iu/ml
—
9
52
17
167
1.02
0.00
1.5
1.5
—
0.01
—
0
20
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.8
—
11.36
—
0
8
0
8
0.00
-0.00
0.0
4.8
—
4.95
—
0
8
0
8
0.00
-0.00
0.0
1.4
—
0.88
—
0
8
0
7
0.00
-0.00
0.0
1.6
—
7.13
—
0
7
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
3.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
12.40
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
1.36
1.44
g/l
—
5
45
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
80
1.00
-0.00
1.0
1.2
—
6639.07
—
0
19
0
7
0.00
-0.00
0.0
1.1
—
1.21
—
0
7
8
80
1.00
-0.00
2.1
3.3
—
191.40
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.3
—
1.77
—
0
7
0
9
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
46.13
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
1.17
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint O15_MATERN_HYPERT_UNS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_MATERN_HYPERT_UNS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_MATERN_HYPERT_UNS – Unspecified maternal hypertension
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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