Magnesium deficiency

E4_MG_DEF

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E61.2#
  • Cause of death: ICD-10 E61.2#

2 out of 7 registries used, show all original rules.

129

4. Check minimum number of events

None

129

5. Include endpoints

None

129

6. Filter based on genotype QC (FinnGen only)

118

Control definitions (FinnGen only)

Control exclude
E4_NUTRIDEF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E61
Name in latin
Deficientia magnesii

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 425 193 228
Only index persons 408 188 220
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 65.03 66.98 63.78
Only index persons 65.36 67.07 63.90

-FinnGen-

Key figures

All Female Male
Number of individuals 118 59 59
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 66.73 67.77 65.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
124
Matched controls
1240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E61.2
ICD-10 Finland
Magnesium deficiency
+∞
179.0
124
*
E87.6
ICD-10 Finland
Hypokalaemia
39.2
70.0
47
19
A49.9
ICD-10 Finland
Bacterial infection, unspecified
10.4
34.3
49
73
E83.51
ICD-10 Finland
Hypocalcemia
222.3
33.5
33
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.9
29.8
62
139
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
6.3
22.4
54
135
N02AA05
ATC
oxycodone; systemic
5.8
21.0
59
168
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
8.7
20.0
29
42
A03FA01
ATC
metoclopramide; systemic, rectal
5.4
19.8
63
198
TPH04
NOMESCO Finland
Cathetrisation of vein
5.2
18.5
60
190
AA1AD
NOMESCO Finland
CT of head and brain
5.1
18.3
70
252
E83.4
ICD-10 Finland
Disorders of magnesium metabolism
+∞
18.2
17
*
WX892
NOMESCO Finland
Monitored bed care
7.6
17.8
29
48
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
7.0
17.5
31
56
TPH07
NOMESCO Finland
Cathetrisation of artery
6.0
17.3
38
85
D64.9
ICD-10 Finland
Anaemia, unspecified
6.0
16.4
35
76
C03CA01
ATC
furosemide; systemic
4.7
16.3
62
219
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.6
16.2
26
42
Z51.5
ICD-10 Finland
Palliative care
6.3
16.0
32
65
R11
ICD-10 Finland
Nausea and vomiting
6.8
15.6
28
51
WX408
NOMESCO Finland
General anesthesy, balanced
4.4
14.8
57
200
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.9
14.5
93
471
130
Kela drug reimbursment
Malignant tumour
5.6
14.4
33
76
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.4
13.9
33
78
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.8
13.8
24
42
R4190
NOMESCO Finland
Nutritional therapy
12.6
13.5
24
23
JN4AD
NOMESCO Finland
Body CT examination
4.8
13.3
37
100
JN3AD
NOMESCO Finland
Abdominal CT examination
4.9
13.2
36
96
H02AB02
ATC
dexamethasone; systemic
4.6
12.5
37
105
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
11.5
12.4
23
24
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.8
12.3
62
257
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.7
12.1
34
92
WW500
NOMESCO Finland
Blood transfusion
10.0
12.0
24
29
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.7
11.2
52
202
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.4
11.1
34
98
ZXE00
NOMESCO Finland
One hour or less
3.6
11.1
69
323
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
4.3
11.0
35
104
J01MA12
ATC
levofloxacin; systemic
3.9
10.9
41
138
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
119.7
10.6
11
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
10.6
10.5
20
22
J01MA02
ATC
ciprofloxacin; systemic
3.4
10.4
70
340
B03BA03
ATC
hydroxocobalamin; parenteral
8.7
10.3
22
30
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
10.2
66
312
WX882
NOMESCO Finland
High dependency care
22.3
10.1
14
7
C03DA01
ATC
spironolactone; oral
4.4
9.7
28
77
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
8.2
9.5
21
30
E53.8
ICD-10 Finland
Deficiency of other specified B group vitamins
+∞
9.5
9
*
R53
ICD-10 Finland
Malaise and fatigue
3.4
9.4
49
202
C08CA01
ATC
amlodipine; oral
3.2
9.3
70
357
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.0
9.3
32
100
UJF32
NOMESCO Finland
Coloscopy
3.3
9.2
49
204
R56.8
ICD-10 Finland
Other and unspecified convulsions
8.3
9.2
20
28
A04AA02
ATC
granisetron; systemic, transdermal
4.8
9.2
23
56
XF600
NOMESCO Finland
Bloodpressure measurement
5.6
9.2
19
39
JDB10
NOMESCO Finland
Percutaneous gastrostomy
20.5
9.1
13
7
C07AB07
ATC
bisoprolol; oral
3.3
9.1
84
481
ZX120
NOMESCO Finland
Intravenous
4.5
9.0
25
66
R4110
NOMESCO Finland
Physiotherapy
3.2
9.0
57
262
B01AB10
ATC
tinzaparin; parenteral
4.1
9.0
29
86
N02AX02
ATC
tramadol; systemic, rectal
3.2
9.0
75
404
E86
ICD-10 Finland
Volume depletion
15.6
8.9
14
10
WF004
NOMESCO Finland
Palliative radiotherapy
12.9
8.8
15
13
A04AA01
ATC
ondansetron; systemic, rectal
4.4
8.7
25
68
WF049
NOMESCO Finland
Radiotherapy of metastasis
7.5
8.6
20
31
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.2
8.6
47
198
A02BC02
ATC
pantoprazole; systemic
4.3
8.5
106
717
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.8
8.4
21
51
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
5.0
8.2
19
43
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.5
8.0
15
16
R50.9
ICD-10 Finland
Fever, unspecified
3.6
8.0
32
110
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
7.9
47
206
A28
ICPC
Limited function/disability NOS
3.3
7.9
38
147
TKC20
NOMESCO Finland
Catheterisation of bladder
4.7
7.9
20
49
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.8
7.8
19
45
N03AX16
ATC
[U] pregabalin
3.1
7.7
43
181
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.1
7.6
44
189
K92.1
ICD-10 Finland
Melaena
6.8
7.4
18
30
ZXD05
NOMESCO Finland
Urgent procedure
2.9
7.4
51
242
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
21.6
7.3
10
5
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.0
7.3
23
67
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
32.1
7.3
9
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
13.1
7.2
12
10
N30.0
ICD-10 Finland
Acute cystitis
3.4
7.1
29
101
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.5
7.0
28
96
L28
ICPC
Limited function/disability (L)
3.1
6.9
36
145
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.6
6.9
17
29
Z3226
NOMESCO Finland
Physiotherapist
3.0
6.8
37
153
JN4BD
NOMESCO Finland
Extensive body CT
3.4
6.7
27
93
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
6.6
54
276
A06AD11
ATC
lactulose; oral
3.3
6.6
29
105
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
6.2
6.6
17
31
N06AX11
ATC
mirtazapine; oral
2.7
6.6
58
308
A46
ICD-10 Finland
Erysipelas
3.4
6.5
27
94
R55
ICD-10 Finland
Syncope and collapse
3.5
6.5
25
83
WX402
NOMESCO Finland
General anaesthesia
2.8
6.5
43
197
D70.82
ICD-10 Finland
Drug-induced neutropenia
11.9
6.4
11
10
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
11.9
6.4
11
10
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.6
6.3
16
39
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
6.2
32
127
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.0
6.2
19
54

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
62
100
11.40
41.50
14.7
11.7
—
—
—
0
0
62
108
10.48
38.65
5.3
4.4
1.85
1.71
mmol/l
0.07
55
92
62
112
10.07
37.33
4.9
4.3
7.39
7.39
ph
0.34
33
71
60
109
9.73
35.77
13.8
9.6
1.35
1.26
mmol/l
0.23
60
109
54
90
9.86
34.50
4.1
3.9
90.33
88.60
ng/l
0.04
45
78
100
326
11.68
34.32
8.6
4.5
—
—
—
0
0
45
65
10.30
32.10
5.3
4.2
24.25
24.39
mmol/l
0.07
45
65
67
158
8.05
30.82
3.0
2.6
20.51
22.87
%
0.63
67
151
55
109
8.27
29.71
4.5
2.5
0.21
0.22
g/l
0.36
48
102
46
76
9.03
29.16
13.2
9.9
24.51
25.20
mmol/l
0.46
46
76
69
177
7.53
28.89
14.3
8.6
102.62
104.26
mmol/l
1.19
69
177
56
120
7.69
27.89
4.6
2.5
423.86
407.43
nmol/l
0.22
51
115
118
596
21.22
27.36
24.6
8.2
1.17
1.21
mmol/l
3.65
109
512
100
384
9.29
27.06
13.1
4.3
7.41
7.40
ph
2.23
77
278
82
274
6.88
25.24
3.3
2.0
2.84
3.15
mg/l
0.41
76
240
55
148
5.88
20.84
14.8
9.6
7.42
7.42
ph
0.04
18
88
55
149
5.84
20.66
14.8
9.5
4.75
5.06
kpa
1.57
55
144
55
149
5.84
20.66
14.8
9.5
11.73
12.39
kpa
0.55
55
144
115
646
11.73
20.39
25.1
12.1
4.43
4.09
e9/l
0.72
96
559
50
129
5.82
19.72
1.9
3.3
2.17
1.84
%
1.06
44
121
83
328
5.63
19.71
6.7
3.0
—
—
—
0
0
68
230
5.33
19.49
9.3
3.2
2.47
2.46
mmol/l
0.07
61
206
81
320
5.42
19.07
5.8
3.0
—
—
estimate
—
0
0
25
32
9.53
19.01
2.4
3.4
69.79
60.31
%
0.93
25
32
89
381
5.73
18.93
10.5
5.9
—
—
—
0
0
82
338
5.21
18.01
6.3
3.1
0.73
0.50
e6/l
0.35
60
246
87
390
5.12
16.80
7.0
3.2
47.19
52.84
e6/l
0.09
66
297
63
223
4.71
16.52
5.2
2.8
503.50
529.74
mosm/kgh2o
0.44
54
195
109
594
7.90
16.36
10.8
6.5
1.67
1.93
e9/l
0.81
90
516
58
194
4.74
16.33
6.5
3.1
5.23
2.21
e6/l
0.96
29
96
108
587
7.51
16.17
10.8
6.6
0.04
0.04
e9/l
0.30
86
494
78
331
4.66
15.94
2.8
1.6
18.89
21.40
nmol/l
0.72
73
270
85
386
4.82
15.82
4.7
2.4
—
—
—
0
0
107
584
7.07
15.72
10.9
6.6
0.66
0.59
e9/l
1.64
85
494
109
606
7.60
15.63
11.1
6.9
0.19
0.18
e9/l
0.14
89
521
39
98
5.35
15.48
2.1
3.6
75.78
73.52
e9/l
0.11
31
72
31
64
6.13
15.22
3.2
2.9
0.55
0.61
%
0.34
31
64
42
115
5.01
15.03
1.4
1.7
—
—
—
0
0
37
92
5.31
14.81
19.5
11.1
0.58
0.66
%
0.49
37
92
47
145
4.61
14.44
2.0
1.6
—
—
—
0
0
101
549
5.53
14.24
4.9
2.8
—
—
estimate
—
0
0
50
164
4.43
14.14
3.5
1.9
—
—
—
0
0
23
38
7.20
13.95
1.8
1.3
225.00
282.41
ug/g
0.76
17
22
88
436
4.51
13.93
9.3
3.9
71.45
122.50
e6/l
0.48
65
302
36
92
5.10
13.89
20.1
11.2
1.26
1.35
%
0.27
36
92
44
134
4.54
13.66
7.7
4.5
6.53
12.27
ug/l
0.79
39
114
52
182
4.20
13.37
2.2
1.6
1027.00
1189.69
nmol/l
0.75
40
134
98
546
4.79
12.70
15.4
10.9
1.23
1.19
inr
0.45
82
444
62
263
3.71
11.79
4.2
2.5
3.62
4.10
e6/l
0.33
55
239
41
131
4.18
11.76
1.3
1.6
—
—
—
0
0
24
50
5.71
11.51
1.9
1.7
0.53
0.43
mg/l
0.24
17
22
89
489
3.91
11.14
3.9
2.0
81.44
97.99
pmol/l
2.16
64
223
56
231
3.60
10.97
9.6
3.6
67.26
252.70
ng/l
0.93
50
192
72
358
3.41
10.30
3.6
3.2
2415.18
1155.25
ng/l
1.33
62
299
71
357
3.31
9.84
16.2
7.0
—
—
—
0
0
16
15
12.05
9.10
3.7
2.1
—
—
—
0
0
16
16
11.29
8.83
1.6
1.5
17.24
40.21
ng/l
0.50
16
16
86
510
3.24
8.56
24.0
12.2
0.01
0.00
e9/l
0.55
63
412
25
71
4.16
8.20
1.2
1.7
—
—
—
0
0
81
477
3.01
7.93
4.6
3.7
6.32
6.24
ph
0.20
38
264
25
76
3.87
7.44
3.7
2.6
—
—
—
0
0
38
155
3.09
7.16
2.0
1.3
573.33
566.00
titre
0.01
12
40
15
21
7.96
6.95
1.1
1.2
—
—
—
0
0
30
110
3.28
6.71
2.0
1.3
—
—
—
0
0
20
58
3.92
6.32
1.6
1.3
—
—
—
0
0
66
379
2.59
6.31
4.5
3.2
6.12
7.66
mmol/l
2.62
59
316
49
246
2.64
6.15
2.4
1.7
1.27
1.24
mg/l
0.04
43
196
39
176
2.77
6.02
1.6
1.7
—
—
—
0
0
14
23
6.72
5.89
5.6
1.7
7.42
7.41
ph
0.24
14
23
37
166
2.75
5.75
2.0
1.3
—
—
—
0
0
88
599
2.62
5.62
7.2
4.0
0.00
0.00
estimate
-0.00
19
125
12
18
7.25
5.40
1.0
1.1
—
—
—
0
0
88
607
2.55
5.34
7.3
4.0
65.38
0.00
estimate
0.48
21
124
12
19
6.87
5.22
3.8
2.2
5.42
7.38
pmol/l
0.71
12
19
63
378
2.36
5.19
5.9
3.9
20.12
9.13
mg/mmol
0.76
45
228
88
613
2.50
5.13
7.3
4.0
0.00
0.00
estimate
-0.00
20
116
124
1118
+∞
5.08
80.8
19.2
3.92
3.97
mmol/l
1.28
124
1096
124
1117
+∞
5.07
80.2
19.2
138.15
139.76
mmol/l
7.08
124
1095
34
155
2.64
5.06
1.8
1.4
—
—
—
0
0
12
20
6.52
5.05
2.3
2.1
4.53
5.75
mmol/24h
0.33
12
20
71
454
2.32
4.98
2.9
2.1
—
—
—
0
0
10
13
8.25
4.95
3.6
2.0
4.67
4.00
e9/l
—
10
13
10
13
8.25
4.95
4.2
1.8
8.12
9.03
kpa
—
10
13
10
13
8.25
4.95
4.2
1.8
4.77
5.28
kpa
—
10
13
54
309
2.32
4.90
3.7
3.1
338.67
337.28
umol/l
0.03
46
261
11
17
6.98
4.89
2.3
1.4
—
—
—
0
0
26
105
2.87
4.85
4.5
4.8
1.50
0.87
%
0.42
16
39
17
53
3.56
4.82
9.5
4.9
36.93
36.93
°c
0.03
17
53
10
14
7.66
4.75
2.4
1.2
—
—
nmol/l
—
0
0
10
14
7.66
4.75
1.3
2.6
11.99
11.09
%
—
10
14
24
94
2.93
4.73
4.6
5.1
0.29
0.25
%
0.07
14
28
106
826
2.95
4.58
6.3
4.2
14.88
14.86
pmol/l
0.02
101
747
60
372
2.19
4.38
4.6
3.3
95.82
53.39
mg/l
0.69
49
234
7
6
12.25
4.33
1.0
1.0
—
—
—
0
0
10
17
6.29
4.22
1.0
1.1
—
—
—
0
0
7
7
10.50
4.06
1.0
1.0
—
—
—
0
0
23
96
2.71
4.02
4.3
5.0
0.77
0.34
%
0.42
13
32
53
324
2.11
3.91
1.3
1.4
—
—
—
0
0
7
8
9.18
3.82
1.0
1.3
177.14
165.08
mmol/24h
—
7
8
6
5
12.51
3.80
2.5
2.0
0.57
0.62
mmol/l
—
6
5
8
12
7.04
3.73
1.0
1.0
1.78
1.45
g/l
—
8
12
11
25
4.72
3.72
3.9
1.8
55.09
57.68
%
0.14
11
25
116
1003
3.42
3.71
8.1
5.2
2.07
1.97
mu/l
0.26
106
911
44
256
2.11
3.65
1.9
1.3
3.22
2.57
g/l
0.51
23
151
29
143
2.34
3.58
1.7
1.3
—
—
—
0
0
124
1152
+∞
3.46
81.6
21.2
82.03
77.66
umol/l
0.87
124
1139
13
38
3.70
3.43
1.4
1.2
—
—
—
0
0
7
10
7.34
3.41
1.0
1.3
—
—
—
0
0
9
19
5.02
3.30
1.6
1.4
—
—
—
0
0
12
34
3.79
3.30
4.9
3.0
1.04
1.60
ratio
—
6
20
6
8
7.81
3.09
1.3
2.5
—
—
—
0
0
6
8
7.81
3.09
1.3
1.9
—
—
—
0
0
38
222
2.03
3.05
1.4
1.3
34.76
23.46
iu/ml
0.25
12
69
10
27
3.93
2.95
1.1
1.1
—
—
—
0
0
8
18
4.67
2.84
1.3
1.5
—
—
—
0
0
15
60
2.71
2.82
3.2
2.3
—
—
—
0
0
64
456
1.83
2.78
6.9
3.6
56.89
35.91
ng/l
0.32
54
329
5
6
8.61
2.77
1.6
4.5
68.20
64.17
nmol/l
—
5
6
9
24
3.96
2.73
1.4
1.8
—
—
—
0
0
6
10
6.24
2.73
1.3
1.7
—
—
—
0
0
6
10
6.24
2.73
1.0
1.4
119.33
95.60
pmol/l
—
6
10
8
19
4.42
2.73
1.3
1.5
—
—
—
0
0
27
146
2.09
2.64
1.4
1.3
—
—
—
0
0
107
910
2.28
2.62
76.1
20.7
14.77
13.69
%
7.60
107
902
8
20
4.20
2.61
1.3
1.5
—
—
—
0
0
8
20
4.20
2.61
1.3
1.5
—
—
—
0
0
8
20
4.20
2.61
1.3
1.5
—
—
—
0
0
25
419
0.49
2.55
4.7
3.2
—
—
—
0
0
17
77
2.40
2.51
6.8
5.1
—
—
—
0
0
124
1176
+∞
2.51
85.6
24.8
3.95
4.50
e12/l
20.94
124
1148
124
1176
+∞
2.51
85.4
24.7
30.73
30.45
pg
0.84
124
1164
124
1176
+∞
2.51
85.4
24.7
92.90
91.38
fl
2.52
124
1164
124
1176
+∞
2.51
90.1
25.4
35.97
40.63
%
22.47
124
1164
124
1176
+∞
2.51
85.7
24.8
7.42
6.58
e9/l
4.57
124
1149
8
21
4.00
2.51
1.5
1.7
—
—
—
0
0
8
21
4.00
2.51
1.5
1.7
—
—
—
0
0
8
21
4.00
2.51
1.5
1.7
—
—
—
0
0
8
21
4.00
2.51
1.5
1.7
—
—
—
0
0
124
1175
+∞
2.51
85.7
24.8
256.86
245.44
e9/l
0.88
124
1155
33
196
1.93
2.49
1.5
1.3
27.87
9.41
u/ml
—
7
63
6
12
5.19
2.43
1.5
1.2
—
—
—
0
0
39
247
1.84
2.42
5.3
6.4
—
—
—
0
0
5
8
6.45
2.39
1.4
1.0
—
—
—
0
0
7
18
4.06
2.29
1.3
1.3
—
—
—
0
0
124
1177
+∞
2.28
86.2
24.9
118.62
135.95
g/l
24.46
124
1164
10
36
2.93
2.19
2.4
2.3
—
—
—
0
0
11
43
2.71
2.14
7.7
3.8
—
—
—
0
0
19
101
2.04
1.94
5.4
5.3
0.00
0.14
%
—
10
28
11
47
2.47
1.83
2.8
2.0
—
—
—
0
0
41
288
1.63
1.71
1.6
1.3
1.00
1.24
u/ml
—
6
65
6
20
3.10
1.60
1.2
1.1
—
—
—
0
0
6
20
3.10
1.60
1.5
1.3
—
—
—
0
0
16
86
1.99
1.59
7.6
3.2
—
—
—
0
0
11
51
2.27
1.55
1.3
1.4
—
—
—
0
0
5
15
3.43
1.54
1.4
3.7
—
—
—
0
0
13
71
1.93
1.25
1.4
1.4
—
58.30
—
0
5
8
37
2.24
1.24
1.1
1.1
—
—
—
0
0
8
37
2.24
1.24
10.4
4.4
4.16
3.93
mmol/l
—
8
37
0
33
0.00
1.18
0.0
1.4
—
—
—
0
0
5
20
2.56
1.16
1.6
2.1
—
—
—
0
0
56
454
1.43
1.12
7.9
3.9
0.00
0.00
estimate
-0.00
16
110
9
45
2.08
1.07
1.1
1.1
—
—
—
0
0
9
48
1.94
1.03
1.3
1.1
—
—
—
0
0
10
55
1.89
0.95
5.1
6.3
0.81
0.88
%
—
10
50
112
1049
1.70
0.94
8.8
6.2
40.11
39.29
mmol/mol
0.34
105
972
6
30
2.05
0.88
1.0
1.4
—
—
—
0
0
20
277
0.67
0.86
2.7
3.1
0.39
0.79
ug/l
5.27
15
175
41
329
1.37
0.84
8.7
3.3
0.00
0.01
estimate
0.50
15
102
34
268
1.37
0.77
7.4
4.3
1.01
1.02
kg/l
0.96
23
182
15
100
1.57
0.77
1.1
1.2
—
—
—
0
0
15
105
1.49
0.63
9.0
4.5
7.41
7.31
ph
2.34
15
70
42
493
0.78
0.63
2.4
2.0
1.67
1.35
mmol/l
1.21
36
405
16
114
1.46
0.62
1.3
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
13
95
1.41
0.46
1.2
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
6
90
0.65
0.34
1.0
1.3
—
—
—
0
0
38
341
1.16
0.28
8.2
3.9
0.00
0.00
estimate
-0.00
18
115
9
72
1.27
0.26
1.4
1.2
137.41
383.39
u/ml
—
9
66
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
6
52
1.16
0.19
1.2
1.1
—
—
—
0
0
103
1049
0.89
0.13
5.0
4.5
1.61
1.27
mmol/l
2.04
93
954
108
1063
1.12
0.11
6.3
5.3
6.25
5.93
mmol/l
1.21
101
971
5
47
1.07
0.09
1.2
2.0
—
—
—
0
0
6
55
1.10
0.09
2.0
2.3
—
0.00
estimate
—
0
14
43
441
0.96
0.04
3.9
5.2
1.38
2.38
ug/l
1.43
38
394
11
114
0.96
0.00
2.1
2.3
15.82
15.41
nmol/l
0.05
11
106
110
1104
0.97
0.00
6.4
6.2
2.27
2.70
mmol/l
5.86
103
1013
109
1087
1.02
0.00
5.4
5.3
1.34
1.48
mmol/l
2.52
100
994
109
1088
1.02
0.00
5.5
5.5
4.18
4.64
mmol/l
4.60
101
1003
0
9
0.00
-0.00
0.0
1.0
—
171.21
—
0
9
0
9
0.00
-0.00
0.0
9.1
—
1174.56
—
0
9
6
66
0.90
-0.00
2.5
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
3.68
—
0
6
6
65
0.92
-0.00
1.3
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_MG_DEF and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_MG_DEF.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_MG_DEF – Magnesium deficiency

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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