Malignant neoplasm of heart, mediastinum and pleura, including Hilmo

C3_HEART_MEDIASTINUM_PLEURA_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C38
  • Hospital discharge: ICD-9 16[3-4]
  • Hospital discharge: ICD-8 163[0-1]
  • Cause of death: ICD-10 C38
  • Cause of death: ICD-9 16[3-4]
  • Cause of death: ICD-8 163[0-1]
  • Cause of death: excluded ICD-9 1640
  • Cancer registry: Topography ICD-O-3 C38
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

809

4. Check minimum number of events

None

809

5. Include endpoints

None

809

6. Filter based on genotype QC (FinnGen only)

726

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 726 205 521
Unadjusted period prevalence (%) 0.19 0.07 0.24
Median age at first event (years) 69.36 62.54 72.05

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
748
Matched controls
7480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A03FA01
ATC
metoclopramide; systemic, rectal
18.1
307.7
391
426
H02AB02
ATC
dexamethasone; systemic
165.6
307.7
311
32
130
Kela drug reimbursment
Malignant tumour
+∞
307.7
365
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
44.5
307.7
310
117
A04AA01
ATC
ondansetron; systemic, rectal
48.9
307.7
212
60
C45.0
ICD-10 Finland
Mesothelioma of pleura
+∞
307.7
323
*
Z51.5
ICD-10 Finland
Palliative care
18.2
248.6
226
174
N02AA05
ATC
oxycodone; systemic
10.5
233.8
385
687
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
20.4
202.5
166
103
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
33.6
198.8
131
47
JN4BD
NOMESCO Finland
Extensive body CT
16.2
198.3
187
151
J94.8
ICD-10 Finland
Other specified pleural conditions
28.4
180.6
126
53
9050/3-C38.4
ICD-O-3
Mesothelioma, malignant of pleura, NOS
+∞
164.8
152
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
9.0
158.9
241
374
TGA30
NOMESCO Finland
Thoracocentesis
69.3
156.8
86
14
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
33.6
156.2
102
35
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
1672.6
145.8
137
*
9052/3-C38.4
ICD-O-3
Epithelioid mesothelioma, malignant of pleura, NOS
+∞
130.1
121
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
8.8
127.6
185
268
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
19.6
125.2
101
59
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
696.1
123.0
118
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
28.7
119.7
82
32
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
237.7
119.5
120
6
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
10.9
112.1
131
143
C38.4
ICD-10 Finland
Malignant neoplasm: Pleura
+∞
110.2
103
*
A04AA02
ATC
granisetron; systemic, transdermal
599.6
107.6
104
*
JN4AD
NOMESCO Finland
Body CT examination
8.0
106.4
166
259
WF049
NOMESCO Finland
Radiotherapy of metastasis
1019.6
94.0
90
*
L03AA02
ATC
filgrastim; parenteral
500.8
91.3
89
*
L03AA13
ATC
pegfilgrastim; parenteral
494.4
90.2
88
*
GD1AD
NOMESCO Finland
Thorax CT examination
8.1
89.8
134
197
C38.1
ICD-10 Finland
Malignant neoplasm: Anterior mediastinum
+∞
89.4
84
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
15.3
89.1
81
59
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
28.7
82.4
56
21
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
233.0
82.1
83
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
81.8
77
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
294.0
79.1
79
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
12.0
78.7
83
77
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
424.8
78.4
77
*
ZX120
NOMESCO Finland
Intravenous
6.6
72.2
130
232
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
68.8
65
*
J94.9
ICD-10 Finland
Pleural condition, unspecified
28.8
67.8
46
17
C38.3
ICD-10 Finland
Malignant neoplasm: Mediastinum, part unspecified
+∞
67.7
64
*
XX3DW
NOMESCO Finland
Time consuming IT work
8.0
65.9
96
136
A04AA55
ATC
palonosetron, combinations; systemic
+∞
65.6
62
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
240.9
65.3
66
*
WW500
NOMESCO Finland
Blood transfusion
12.4
64.6
66
58
GAC00
NOMESCO Finland
Biopsy of pleura
103.3
61.0
66
7
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
19.7
60.9
48
26
N02AA01
ATC
morphine; systemic, rectal
14.3
60.2
56
42
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
613.8
58.5
57
*
L01CA04
ATC
vinorelbine; systemic
+∞
58.1
55
*
WF002
NOMESCO Finland
Radical radiotherapy
110.5
56.7
61
6
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
53.8
51
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
48.5
46
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
498.2
47.9
47
*
WZC00
NOMESCO Finland
Treatment plan or consultation
3.2
46.4
270
1137
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
46.2
460
2600
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
464.1
44.7
44
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
44.2
42
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.1
43.5
55
65
WZC30
NOMESCO Finland
Teaching
3.8
43.3
153
469
1BA04, ,
NOMESCO Finland
+∞
42.1
40
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
42.1
40
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
42.1
40
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
64.0
41.7
48
8
C45.9
ICD-10 Finland
Mesothelioma, unspecified
+∞
41.0
39
*
C38.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of heart, mediastinum and pleura
+∞
40.0
38
*
9051/3-C38.4
ICD-O-3
Fibrous mesothelioma, malignant of pleura, NOS
+∞
38.9
37
*
JN4CD
NOMESCO Finland
Very extensive body CT
11.1
38.7
42
40
R84
ICPC
Malignant neoplasm bronchus/lung
396.8
38.4
38
*
116
Kela drug reimbursment
Prostate cancer
+∞
37.8
36
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
37.8
155
522
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
36.4
222
942
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
12.6
36.1
36
30
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
133.3
36.0
38
*
GAA31
NOMESCO Finland
Thoracoscopy
133.3
36.0
38
*
A04AD12
ATC
aprepitant; systemic
+∞
34.6
33
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
125.9
34.0
36
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
33.6
32
*
J01MA12
ATC
levofloxacin; systemic
2.9
33.6
201
840
J01MA14
ATC
moxifloxacin; systemic
3.7
32.3
116
356
A06AH03
ATC
naloxegol; oral
45.6
32.1
39
9
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
330.5
32.1
32
*
C83.33
ICD-10 Finland
Primary medical lymphoma with large B cells
+∞
31.5
30
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.7
31.4
78
182
AA1BD
NOMESCO Finland
Extensive CT of head and brain
8.9
30.7
39
46
A79
ICPC
Malignancy NOS
+∞
30.4
29
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
86.3
30.0
33
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.5
29.7
39
48
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
29.4
28
*
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
+∞
29.4
28
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
29.4
28
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
29.4
28
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
11.1
28.8
31
29
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
28.3
209
964
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
291.9
27.9
28
*
H02AB06
ATC
prednisolone; systemic
2.3
27.7
398
2463
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
27.2
26
*
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
+∞
27.2
26
*
L02AE02
ATC
leuprorelin; implant, parenteral
43.1
27.0
33
8
D70.82
ICD-10 Finland
Drug-induced neutropenia
78.2
27.0
30
*
9679/3-C38.3
ICD-O-3
Mediastinal large B-cell lymphoma of mediastinum, NOS
+∞
26.2
25
*
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
+∞
26.2
25
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
269.5
25.9
26
*
TK800
NOMESCO Finland
Hemodialysis
7.2
25.7
39
57
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
25.6
197
921
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
25.1
24
*
GA2AT
NOMESCO Finland
Pleural biopsy with ultrasound guidance
+∞
25.1
24
*
L01CB01
ATC
etoposide; systemic
+∞
24.1
23
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
24.1
23
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
24.1
23
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
8.3
24.0
32
40
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
23.7
309
1807
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
48.4
23.5
28
6
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
23.0
22
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
23.0
22
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
23.0
22
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
53.8
22.2
26
5
8000/3-C38.4
ICD-O-3
Neoplasm, malignant of pleura, NOS
+∞
22.0
21
*
115
Kela drug reimbursment
Breast cancer
+∞
22.0
21
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
22.0
21
*
R06.0
ICD-10 Finland
Dyspnoea
2.2
21.9
267
1510
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
82.6
21.8
24
*
R85
ICPC
Malignant neopl respiratory other
226.3
21.7
22
*
Z2446
NOMESCO Finland
Social worker
3.8
21.4
70
200
JN6AD
NOMESCO Finland
CT of torso and neck
24.0
21.4
30
13
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
4.9
21.3
48
103
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
20.9
20
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
20.9
20
*
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
+∞
20.9
20
*
9663/3-C38.3
ICD-O-3
Hodgkin lymphoma, nodular sclerosis, NOS, of mediastinum, NOS
+∞
20.9
20
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
20.9
20
*
B01AB05
ATC
enoxaparin; parenteral
2.2
20.8
239
1315
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
19.9
19
*
L02BB03
ATC
bicalutamide; oral
+∞
19.9
19
*
9053/3-C38.4
ICD-O-3
Mesothelioma, biphasic, malignant of pleura, NOS
+∞
19.9
19
*
C34.82
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary adenocarcinoma
+∞
19.9
19
*
XW000
NOMESCO Finland
Bone marrow biopsy
5.1
19.7
42
86
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
205.2
19.6
20
*
B03BA03
ATC
hydroxocobalamin; parenteral
3.3
19.6
80
264
GEA00
NOMESCO Finland
Mediastinoscopy
47.3
19.3
23
5
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
18.8
119
500
9680/3-C38.3
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of mediastinum, NOS
+∞
18.8
18
*
C37
ICD-10 Finland
Malignant neoplasm of thymus
+∞
18.8
18
*
QBC00
NOMESCO Finland
Removal of foreign body from skin of trunk or subcutaneous tissue
194.7
18.6
19
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
194.7
18.6
19
*
N03AX16
ATC
[U] pregabalin
2.2
18.1
177
906
GEB30
NOMESCO Finland
Mediastinotomy and excision of lesion
97.4
17.6
19
*
WX600
NOMESCO Finland
Single shot through catheter
16.1
17.6
28
18
Z51.0
ICD-10 Finland
Radiotherapy session
184.2
17.6
18
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
17.4
78
272
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
17.0
267
1628
R50.9
ICD-10 Finland
Fever, unspecified
2.4
16.8
131
607
C38.2
ICD-10 Finland
Malignant neoplasm: Posterior mediastinum
+∞
16.7
16
*
C38.0
ICD-10 Finland
Malignant neoplasm: Heart
+∞
16.7
16
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
16.7
16
*
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
173.7
16.6
17
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.7
16.1
30
54
N02AX02
ATC
tramadol; systemic, rectal
1.9
15.8
325
2159
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
15.7
15
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
15.7
15
*
C45.1
ICD-10 Finland
Mesothelioma of peritoneum
+∞
15.7
15
*
GDD20
NOMESCO Finland
Extended pneumonectomy
+∞
15.7
15
*
C34.80
ICD-10 Finland
Malignant overall tumor of bronchus and lung without histology
+∞
15.7
15
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
15.7
15
*
L01BC06
ATC
capecitabine; oral
+∞
15.7
15
*
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
26.9
15.7
21
8
R82
ICPC
Pleurisy/pleural effusion
86.9
15.6
17
*
GAC43
NOMESCO Finland
Total decortication of pleura
163.3
15.5
16
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
15.5
279
1771
B01AB10
ATC
tinzaparin; parenteral
2.9
15.4
78
291
R4110
NOMESCO Finland
Physiotherapy
2.0
15.3
206
1183
ZXE00
NOMESCO Finland
One hour or less
1.9
15.2
276
1755
WW200, ,
SPAT
0.3
15.1
61
1526
J86.9
ICD-10 Finland
Pyothorax without fistula
11.6
14.9
27
24
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
57.9
14.8
17
*
C45
ICD-10 Finland
Mesothelioma
+∞
14.6
14
*
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
+∞
14.6
14
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
14.6
14
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
14.6
14
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
14.6
164
880
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
36.8
14.5
18
5
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
22.8
14.3
20
9
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.3
14.0
28
54
ZX112
NOMESCO Finland
Subcutaneous
16.1
14.0
22
14
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.2
13.7
57
190
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
13.6
13
*
GEC23
NOMESCO Finland
Transsternal thymectomy
+∞
13.6
13
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
13.6
13
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
13.6
13
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
13.6
13
*
N05BA06
ATC
lorazepam; systemic, sublingual
3.0
13.6
61
213
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.0
13.5
39
102
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
13.3
100
454
1XC02, ,
NOMESCO Finland
40.9
13.2
16
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
13.2
120
591
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.2
13.2
35
86
A02BC02
ATC
pantoprazole; systemic
1.8
13.1
471
3633
GAC97
NOMESCO Finland
Other endoscopic operation on pleura
28.9
13.0
17
6
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
13.3
13.0
22
17
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
19.5
13.0
19
10
Z2221
NOMESCO Finland
Medical doctor
1.9
12.9
188
1101
Z3231
NOMESCO Finland
Registered nurse
1.9
12.8
194
1152
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
12.5
12
*
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
+∞
12.5
12
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
12.5
12
*
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
+∞
12.5
12
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
12.5
12
*
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
+∞
12.5
12
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
12.5
12
*
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
+∞
12.5
12
*
GAC30
NOMESCO Finland
Artificial pneumothorax
+∞
12.5
12
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
12.5
12
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.9
12.5
60
217
Y77
ICPC
Malignant neoplasm prostate
132.1
12.5
13
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
132.1
12.5
13
*
L02BA01
ATC
tamoxifen; oral
132.1
12.5
13
*
GDC00
NOMESCO Finland
Lobectomy of lung
132.1
12.5
13
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
132.1
12.5
13
*
HA1AA
NOMESCO Finland
X-ray mammography
5.0
12.5
27
56
WX402
NOMESCO Finland
General anaesthesia
2.1
12.4
130
675
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
4.6
12.2
29
65
L02BG04
ATC
letrozole; oral
12.7
12.2
21
17
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.1
12.1
7
476
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
21.7
12.0
17
8
SPAT1109
SPAT
Analgesia with portable analgesic pump
21.7
12.0
17
8
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.7
12.0
38
106
N05CF01
ATC
zopiclone; oral
1.8
11.9
254
1671
NK6AN
NOMESCO Finland
Total body bone isotope imaging
47.5
11.9
14
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.5
11.9
23
43
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
30.6
11.7
15
5
GA3AT
NOMESCO Finland
Pleural cytology with ultrasound guidance
19.3
11.6
17
9
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
11.5
11
*
GDD96
NOMESCO Finland
Other pneumonectomy
+∞
11.5
11
*
GAC37
NOMESCO Finland
Endoscopic chemical pleurodesis
121.8
11.5
12
*
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
35.6
11.3
14
*
GEA20
NOMESCO Finland
Mediastinoscopy with excision of lesion
60.9
10.6
12
*
R4190
NOMESCO Finland
Nutritional therapy
4.5
10.6
26
60
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.9
10.6
49
174
JN5KR
NOMESCO Finland
Very extensive PET-CT of upper body metabolism (eyebrows to thighs)
111.5
10.4
11
*
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
111.5
10.4
11
*
A04AA03
ATC
tropisetron; systemic
+∞
10.4
10
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
10.4
10
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
10.4
10
*
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
10.4
10
*
8070/3-C32.9
ICD-O-3
Squamous cell carcinoma, NOS, of larynx, NOS
+∞
10.4
10
*
GA2CT
NOMESCO Finland
Pleural biopsy with CT guidance
+∞
10.4
10
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
10.4
10
*
GD2FN
NOMESCO Finland
Lung ventilation distribution isotope examination (radiospirometry)
+∞
10.4
10
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
33.0
10.4
13
*
TGD00
NOMESCO Finland
Needle biopsy of lung
33.0
10.4
13
*
TGC00
NOMESCO Finland
Bronchial lavation
4.1
10.3
28
70
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.9
10.2
49
178
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.6
10.1
24
54
C10AA07
ATC
rosuvastatin; oral
0.5
9.9
88
1638
WW200
NOMESCO Finland
Immunization
4.0
9.9
28
72
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.7
9.8
19
20
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.3
9.7
37
117
P20
ICPC
Memory disturbance
0.3
9.7
37
974
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
101.3
9.4
10
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
101.3
9.4
10
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
101.3
9.4
10
*
J93.9
ICD-10 Finland
Pneumothorax, unspecified
17.8
9.4
14
8
GAC20
NOMESCO Finland
Excision or destruction of lesion of pleura
+∞
9.4
9
*
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
9.4
9
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
9.4
9
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
9.4
9
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
9.4
9
*
C34.89
ICD-10 Finland
Malignant overall tumor of the bronchus and lung other or unspecified histology
+∞
9.4
9
*
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
+∞
9.4
9
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
9.4
9
*
N06DA02
ATC
donepezil; oral
0.2
9.1
9
435
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
37.2
9.0
11
*
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.4
8.9
22
51
B01AB04
ATC
dalteparin; parenteral
3.0
8.7
39
136
GAC46
NOMESCO Finland
Partial decortication of pleura
50.6
8.7
10
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
8.5
88
453
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
91.1
8.4
9
*
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
8.3
8
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
8.3
8
*
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
+∞
8.3
8
*
1638X
ICD-9 Finland
Malignant neoplasm of pleura, Other specified sites of pleura
+∞
8.3
8
*
8000/3-C38.3
ICD-O-3
Neoplasm, malignant of mediastinum, NOS
+∞
8.3
8
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
8.3
8
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
8.3
8
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
8.3
8
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
8.3
8
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
8.3
8
*
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
+∞
8.3
8
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.7
8.3
17
20
XX2RW, ,
NOMESCO Finland
10.9
8.3
15
14
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
22.3
8.0
11
5
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
22.3
8.0
11
5
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
7.9
58
1166
M79.6
ICD-10 Finland
Pain in limb
0.6
7.9
132
2043
A06AD11
ATC
lactulose; oral
1.8
7.7
133
810
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
45.5
7.7
9
*
N06DX01
ATC
memantine; oral
0.2
7.6
15
566
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
7.6
320
2439
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
3.6
7.6
25
72
WZC30, ,
SPAT
0.2
7.5
9
389
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.6
7.5
24
68
H02AB07
ATC
prednisone; oral
1.9
7.4
100
564
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
6.6
7.4
18
28
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.1
7.4
*
290
A98
ICPC
Health maint/preventive medicine
0.6
7.4
509
5767
HAC20
NOMESCO Finland
Total mastectomy
80.9
7.4
8
*
GAC36
NOMESCO Finland
Chemical pleurodesis
80.9
7.4
8
*
I87.1
ICD-10 Finland
Compression of vein
80.9
7.4
8
*
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
13.5
7.4
12
9
Z31.6
ICD-10 Finland
General counselling and advice on procreation
11.0
7.3
13
12
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
7.3
7
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
7.3
7
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
7.3
7
*
GWE00
NOMESCO Finland
Reoperation for deep haemorrhage in thoracic surgery
+∞
7.3
7
*
1649X
ICD-9 Finland
Malignant neoplasm of thymus, heart and mediastinum, Mediastinum, part unspecified
+∞
7.3
7
*
C80.92
ICD-10 Finland
Malignant tumor without specified localization adenocarcinoma
+∞
7.3
7
*
FFA10
NOMESCO Finland
Excision of lesion of atrium
+∞
7.3
7
*
8010/3-C34.9
ICD-O-3
Carcinoma, NOS, of lung, NOS
+∞
7.3
7
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
7.3
7
*
Z08.9
ICD-10 Finland
Follow-up examination after unspecified treatment for malignant neoplasm
+∞
7.3
7
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
7.3
7
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
7.3
7
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
+∞
7.3
7
*
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
+∞
7.3
7
*
159
Kela drug reimbursment
Pazopanib
+∞
7.3
7
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
7.3
7
*
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.9
7.3
19
33
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.1
7.2
30
101
GD6AD
NOMESCO Finland
CT of chest and neck
20.2
7.1
10
5
R93.8
ICD-10 Finland
Abnormal findings on diagnostic imaging of other specified body structures
20.2
7.1
10
5
SPAT1053
SPAT
Memory test
0.4
7.1
40
896
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.7
7.1
17
26
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
6.9
158
1040
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.6
6.8
153
2218
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
11.1
6.8
12
11
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
0.1
6.8
*
250
ZXC96
NOMESCO Finland
Robot assisted procedure
16.9
6.8
10
6
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
22.7
6.7
9
*
J93.8
ICD-10 Finland
Other pneumothorax
12.4
6.6
11
9
N06DA03
ATC
rivastigmine; oral, transdermal
0.2
6.5
6
303
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
0.1
6.5
*
218
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.3
6.4
48
217
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
70.4
6.4
7
*
GDB10
NOMESCO Finland
Wedge resection of lung
70.4
6.4
7
*
WPA16, ,
SPAT
70.4
6.4
7
*
ZZR00
NOMESCO Finland
Flap of skin
14.5
6.4
10
7
C10AA05
ATC
atorvastatin; oral
0.6
6.3
190
2587
J01FF01
ATC
clindamycin; systemic
1.6
6.3
169
1155
C32.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of larynx
+∞
6.3
6
*
9680/3-C38.4
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of pleura, NOS
+∞
6.3
6
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
6.3
6
*
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
+∞
6.3
6
*
GE1CT
NOMESCO Finland
Mediastinal biopsy with CT guidance
+∞
6.3
6
*
GCA32
NOMESCO Finland
Endoscopic insertion of stent into bronch
+∞
6.3
6
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
6.3
6
*
GEW99
NOMESCO Finland
Other operation on mediastinum
+∞
6.3
6
*
C34.86
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary microcellular carcinoma
+∞
6.3
6
*
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
+∞
6.3
6
*
C45.7
ICD-10 Finland
Mesothelioma of other sites
+∞
6.3
6
*
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
+∞
6.3
6
*
C34.0
ICD-10 Finland
Malignant neoplasm: Main bronchus
+∞
6.3
6
*
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
+∞
6.3
6
*
L01AX03
ATC
temozolomide; systemic
+∞
6.3
6
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
6.3
6
*
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
+∞
6.3
6
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
6.3
6
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
GDA96
NOMESCO Finland
Other incision, excision of lesion or repair of lung
+∞
6.3
6
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
6.3
6
*
R92
ICPC
Neoplasm respiratory unspecified
+∞
6.3
6
*
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
+∞
6.3
6
*
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
6.3
126
1882
D38.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Respiratory organ, unspecified
26.9
6.2
8
*
I10
ICD-10 Finland
Essential (primary) hypertension
0.7
6.2
324
3958
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
12.6
6.1
10
8
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
8.7
6.1
12
14
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
10.1
6.0
11
11
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
196
57
46.24
320.51
2.3
1.4
—
—
—
0
0
219
94
32.53
316.86
1.9
1.4
40.41
26.50
g/l
16.73
209
83
254
140
26.96
307.65
1.7
1.2
—
—
—
0
0
185
66
36.91
283.91
1.9
1.4
—
—
—
0
0
191
80
31.72
277.47
2.0
1.4
1866.56
1703.24
e6/l
0.14
147
54
177
68
33.79
264.56
2.0
1.4
52729.36
134354.39
e6/l
0.40
121
38
149
66
27.94
210.27
1.7
1.3
4.72
6.95
mmol/l
6.13
142
59
142
68
25.54
193.96
1.9
1.4
—
—
—
0
0
84
18
52.44
145.22
1.5
1.2
10.44
2.35
ug/l
—
35
6
194
296
8.50
127.99
2.3
1.4
15.47
2.77
ug/l
0.80
153
209
84
39
24.14
114.87
1.5
1.3
7.36
7.41
ph
0.75
72
25
277
853
4.57
82.78
2.3
2.1
—
—
—
0
0
256
910
3.76
60.00
5.4
2.6
0.78
0.83
mmol/l
11.57
244
845
361
1793
2.96
46.07
8.6
5.0
—
—
—
0
0
357
1780
2.92
44.96
6.1
4.3
—
—
—
0
0
59
76
8.34
43.53
2.3
2.7
—
—
—
0
0
50
9
59.38
42.97
1.3
1.0
—
—
—
0
0
313
1557
2.74
38.14
2.8
1.7
—
—
—
0
0
428
2505
2.66
37.23
9.2
5.3
2.48
2.97
%
4.51
423
2331
428
2506
2.65
37.19
9.3
5.3
9.59
9.09
%
2.54
421
2336
428
2511
2.65
36.95
9.3
5.3
0.57
0.65
%
2.53
423
2339
429
2555
2.59
35.35
9.2
5.3
20.60
26.01
%
19.69
424
2410
474
2968
2.63
35.04
19.9
5.9
4.73
4.47
e9/l
0.99
422
2528
126
402
3.57
33.12
1.3
1.1
—
—
—
0
0
38
44
9.05
30.38
2.1
1.5
58.04
23.52
ng/l
0.67
38
44
439
2764
2.42
30.32
8.8
5.2
0.71
0.62
e9/l
7.54
381
2339
438
2774
2.40
29.57
8.8
5.2
0.04
0.04
e9/l
0.98
383
2354
441
2812
2.38
29.15
8.8
5.3
1.50
1.79
e9/l
10.21
392
2436
408
2521
2.36
28.94
6.9
4.0
31.83
35.15
g/l
19.41
394
2327
440
2862
2.31
26.94
9.4
5.3
0.18
0.21
e9/l
1.99
392
2446
152
642
2.72
24.16
1.5
1.5
—
—
—
0
0
251
1343
2.31
23.91
8.5
3.8
85.74
81.77
%
2.01
246
1313
91
289
3.45
23.81
1.4
1.4
—
—
—
0
0
433
2952
2.11
21.62
10.3
6.4
1.21
1.20
mmol/l
0.59
396
2517
289
1704
2.13
21.12
5.3
3.2
7.40
7.40
ph
1.50
221
1222
290
1724
2.11
20.64
3.3
2.2
—
—
—
0
0
397
2651
2.06
20.60
9.9
6.3
1.21
1.20
mmol/l
0.82
390
2401
218
1165
2.23
20.31
5.9
2.1
2.50
2.44
mmol/l
12.33
202
1014
83
275
3.27
20.22
2.1
1.7
0.94
2.19
ug/l
1.22
78
234
428
2963
2.04
19.81
11.3
19.5
1.17
1.38
inr
17.68
349
2503
46
102
4.74
19.63
1.6
2.0
56.65
15.24
u/ml
0.43
40
76
391
5157
0.49
19.59
5.5
7.2
39.85
40.36
mmol/mol
0.55
350
4769
302
1868
2.03
18.93
8.0
2.0
2.36
2.35
mmol/l
1.61
285
1616
232
1307
2.12
18.68
3.1
2.2
—
—
—
0
0
46
110
4.39
17.89
1.8
1.4
9.63
7.91
u/l
0.43
38
92
16
0
+∞
16.73
8.0
0.0
0.25
—
umol/l
—
16
0
120
2241
0.45
14.84
1.5
1.9
1.36
1.29
mmol/l
0.53
98
1852
414
5209
0.54
14.80
3.9
5.3
1.42
1.40
mmol/l
0.54
364
4749
432
5368
0.54
14.79
4.3
6.2
2.53
2.50
mmol/l
0.30
374
4918
421
5260
0.54
14.47
3.9
5.4
4.37
4.33
mmol/l
0.32
372
4836
30
61
5.08
14.15
4.5
2.4
1.70
1.12
%
0.36
30
49
22
17
13.29
12.98
6.2
1.9
3.10
3.85
nmol/l
0.29
22
17
132
2265
0.49
12.25
2.5
3.4
7.75
7.75
mmol/l
0.00
111
1910
148
813
2.02
12.16
10.8
8.3
1.51
1.05
mmol/l
0.80
134
672
22
20
11.30
12.09
1.3
1.2
—
—
—
0
0
127
2194
0.49
11.95
2.5
3.5
18.00
50.17
mg/l
6.41
74
1471
19
13
14.96
11.83
1.3
1.2
1.91
1.03
mmol/l
—
19
7
148
823
2.00
11.72
10.7
8.3
7.41
7.42
ph
0.32
72
483
187
1130
1.87
11.54
2.1
1.7
1.73
1.39
mg/l
0.87
154
884
23
26
9.09
11.32
2.4
2.8
32.95
49.18
%
4.05
23
26
256
1710
1.76
11.30
4.5
2.6
30.12
36.01
u/l
1.93
245
1607
41
126
3.38
11.24
2.8
3.9
—
—
—
0
0
22
42
5.37
11.12
1.4
1.2
—
—
—
0
0
404
4979
0.59
11.11
3.5
4.5
1.22
1.26
mmol/l
0.46
351
4495
341
2480
1.69
10.95
3.7
2.6
—
—
estimate
—
0
0
134
736
2.00
10.94
1.7
1.8
—
—
—
0
0
135
2234
0.52
10.87
3.3
4.2
2.92
8.74
mg/mmol
5.33
71
1455
93
446
2.24
10.81
5.6
3.7
1.33
0.76
%
1.06
49
105
237
1567
1.75
10.74
13.2
4.3
—
—
—
0
0
98
487
2.16
10.42
1.5
1.5
—
—
—
0
0
15
8
19.10
10.29
1.3
1.1
24.73
11.07
g/l
—
15
8
88
421
2.24
10.28
4.8
3.6
0.88
0.58
%
0.69
47
103
18
16
11.50
10.09
2.2
2.9
78.44
145.75
e6/l
0.67
18
16
93
460
2.17
10.00
4.8
4.3
7.42
7.41
ph
1.34
86
371
88
430
2.19
9.75
5.8
3.7
0.16
0.06
%
0.98
45
88
111
593
2.02
9.74
1.6
1.6
—
—
—
0
0
73
333
2.32
9.53
4.9
4.4
—
—
—
0
0
138
803
1.88
9.42
5.5
5.1
1.03
1.03
mmol/l
0.13
130
734
15
11
13.88
9.21
4.1
1.2
77.00
77.09
nmol/l
0.00
15
11
448
5299
0.61
9.19
4.7
5.5
6.07
6.11
mmol/l
0.19
399
4773
86
430
2.13
8.99
1.4
1.5
—
—
—
0
0
323
2417
1.59
8.63
17.7
10.1
0.00
0.00
e9/l
1.00
245
1962
19
40
4.85
8.63
5.3
3.4
—
—
—
0
0
423
5038
0.63
8.50
6.1
4.8
2.18
1.99
mu/l
0.94
386
4549
501
4168
1.61
8.40
17.4
5.6
86.50
78.03
u/l
4.10
494
3868
14
11
12.94
8.39
1.2
1.2
36.50
18.00
u/l
—
14
6
14
11
12.94
8.39
2.9
1.2
—
—
—
0
0
226
1568
1.63
8.17
3.1
3.0
—
0.00
estimate
—
0
12
14
12
11.86
8.10
1.9
3.6
36.64
23.08
%
1.80
14
12
14
12
11.86
8.10
2.0
3.5
5.07
5.83
%
0.10
14
12
30
94
3.28
8.02
1.5
2.5
—
—
—
0
0
195
1313
1.66
7.90
5.1
4.4
152.07
428.32
ng/l
2.51
172
1116
57
255
2.34
7.79
5.2
4.9
26.15
24.77
mmol/l
2.33
57
229
85
449
2.01
7.66
5.9
3.9
0.10
0.01
%
1.08
41
84
103
583
1.89
7.59
14.4
9.0
—
—
—
0
0
234
1675
1.58
7.29
3.1
3.0
0.57
0.41
e6/l
0.43
177
1222
28
91
3.16
7.08
2.4
2.1
123.26
9482.14
u/l
—
10
30
427
3497
1.52
7.07
9.3
5.3
6.60
6.84
mmol/l
2.27
417
3331
22
61
3.69
7.07
1.2
1.3
—
—
—
0
0
87
480
1.92
6.92
2.5
2.1
32.31
34.14
u/l
0.21
74
379
216
2890
0.64
6.72
1.8
2.2
95.81
93.65
pmol/l
0.26
133
1548
32
117
2.81
6.62
3.9
4.5
2.76
2.52
mmol/l
0.25
26
75
11
9
12.38
6.59
1.0
1.0
—
—
—
0
0
16
26
6.26
6.49
1.3
1.1
—
—
—
0
0
29
102
2.92
6.43
1.9
1.3
24.16
19.72
iu/l
0.28
23
89
84
1401
0.55
6.32
4.0
4.1
1.02
1.02
kg/l
0.32
64
913
49
229
2.22
6.08
1.1
1.3
—
—
—
0
0
133
869
1.65
5.92
11.6
7.3
103.55
104.60
mmol/l
1.61
133
869
526
5844
0.66
5.85
50.8
24.1
125.37
135.47
g/l
35.74
519
5748
526
5843
0.66
5.83
50.2
24.0
7.64
6.91
e9/l
3.98
510
5672
526
5842
0.66
5.81
50.0
23.9
29.73
30.52
pg
16.30
518
5747
526
5842
0.66
5.81
50.1
23.9
4.28
4.47
e12/l
12.46
510
5668
526
5842
0.66
5.81
52.1
24.5
38.25
40.33
%
18.27
518
5745
18
50
3.66
5.79
4.7
2.6
63.19
58.10
%
0.45
18
40
526
5840
0.67
5.77
50.0
23.9
90.62
91.65
fl
5.06
518
5745
526
5839
0.67
5.75
50.2
24.0
276.48
236.00
e9/l
19.29
512
5684
35
145
2.48
5.70
4.3
3.8
1.24
1.72
index
0.25
25
79
151
1035
1.58
5.50
2.1
2.5
9.97
12.49
umol/l
5.25
145
945
256
1963
1.46
5.47
3.2
3.1
21.22
122.72
e6/l
2.07
197
1495
164
1164
1.52
5.08
2.5
2.7
538.36
544.41
mosm/kgh2o
0.13
150
1005
230
1767
1.44
4.75
4.0
2.4
52.71
60.13
u/l
1.61
222
1627
38
178
2.20
4.74
1.2
1.3
0.26
0.22
g/l
2.25
38
173
13
26
5.07
4.64
5.3
2.9
0.54
0.96
index
1.36
13
26
7
5
14.11
4.58
4.9
6.0
8.29
9.40
%
—
7
5
7
5
14.11
4.58
2.4
3.0
35.29
37.20
%
—
7
5
20
70
2.91
4.52
1.6
1.4
—
—
—
0
0
20
70
2.91
4.52
1.6
1.4
—
—
—
0
0
20
70
2.91
4.52
1.6
1.4
—
—
—
0
0
20
70
2.91
4.52
1.6
1.4
—
—
—
0
0
524
5754
0.70
4.51
42.4
21.3
78.82
85.06
umol/l
4.18
517
5659
38
182
2.15
4.50
1.4
1.4
1.13
1.14
g/l
0.06
38
176
12
23
5.28
4.47
2.7
2.3
40.00
46.75
%
—
7
13
271
2164
1.40
4.44
3.7
3.7
92.06
101.51
e6/l
0.07
203
1530
155
1122
1.48
4.32
6.7
4.1
—
—
—
0
0
105
699
1.58
4.30
1.4
1.3
412.31
522.73
titre
0.51
26
161
135
955
1.50
4.21
3.0
3.0
2.23
1.72
e6/l
0.26
65
466
275
2217
1.38
4.20
3.6
3.3
1194.99
1764.43
ng/l
2.58
260
1940
172
2244
0.70
4.14
3.7
3.8
0.00
0.01
estimate
0.50
53
495
24
98
2.50
4.08
4.5
2.7
61.84
58.77
%
0.45
24
98
238
2932
0.72
4.04
5.4
4.5
2.48
2.19
ug/l
0.74
203
2615
89
583
1.60
3.91
2.8
2.2
6.33
9.21
umol/l
1.58
80
514
149
1972
0.69
3.84
1.5
1.7
21.68
19.55
nmol/l
0.99
137
1648
516
5638
0.73
3.83
21.6
10.3
24.74
25.62
u/l
0.59
508
5406
191
1472
1.40
3.76
1.5
1.3
—
—
—
0
0
501
5491
0.73
3.71
27.8
14.8
—
—
—
0
0
18
67
2.73
3.68
2.1
2.1
—
—
—
0
0
130
1742
0.69
3.55
2.8
3.5
—
—
—
0
0
12
31
3.92
3.50
1.3
1.0
—
—
—
0
0
358
4099
0.76
3.49
5.2
3.7
15.14
14.98
pmol/l
0.54
334
3663
83
552
1.57
3.43
5.6
3.6
7.39
7.36
ph
2.41
78
355
20
82
2.48
3.41
4.1
2.8
4.09
4.39
e9/l
0.28
20
82
519
5631
0.74
3.32
38.1
20.7
4.00
4.01
mmol/l
0.57
511
5492
32
163
2.01
3.29
2.2
2.3
121.19
131.62
g/l
1.01
21
129
519
5627
0.75
3.27
37.9
20.6
138.53
139.77
mmol/l
16.77
512
5496
14
49
2.89
3.20
1.4
1.2
—
—
—
0
0
198
2443
0.74
3.20
2.3
2.3
77.13
78.26
nmol/l
0.21
178
2113
190
1506
1.35
3.09
3.9
2.6
306.97
367.68
umol/l
9.96
173
1282
31
564
0.53
3.08
1.6
1.6
—
—
—
0
0
9
22
4.13
2.89
1.2
1.1
—
—
—
0
0
7
13
5.42
2.87
1.4
1.8
—
—
—
0
0
22
104
2.15
2.77
1.6
1.8
4.10
56.28
iu/l
—
5
44
15
60
2.53
2.71
1.5
1.1
—
—
—
0
0
19
86
2.24
2.65
1.5
1.2
—
—
—
0
0
16
67
2.42
2.64
2.3
1.8
89.72
90.25
%
0.18
16
67
257
2994
0.78
2.55
3.5
3.8
26.23
0.00
estimate
0.49
61
612
23
115
2.03
2.53
2.6
1.2
—
—
—
0
0
23
116
2.01
2.48
1.7
1.2
—
—
—
0
0
170
1371
1.31
2.42
2.6
2.4
4.22
4.49
e6/l
0.19
159
1239
259
3001
0.79
2.41
3.5
3.8
0.00
0.01
estimate
0.93
55
579
108
1406
0.73
2.41
1.6
1.8
548.17
11491645.47
pmol/l
0.73
86
1140
5
8
6.28
2.37
1.2
1.0
—
—
—
0
0
133
1038
1.34
2.37
3.0
2.8
1.26
1.19
e6/l
0.06
63
551
8
22
3.66
2.37
1.5
1.1
—
—
—
0
0
107
809
1.38
2.33
3.7
2.0
1.67
1.74
%
0.31
98
711
22
112
1.99
2.32
2.0
1.8
319.95
289.85
mu/l
0.20
22
104
64
442
1.49
2.28
3.7
5.6
—
—
—
0
0
255
2945
0.80
2.27
3.5
3.8
0.00
0.00
estimate
-0.00
59
597
13
281
0.45
2.20
2.2
1.9
—
—
—
0
0
41
258
1.62
2.20
1.1
1.3
—
—
—
0
0
89
666
1.38
2.08
1.7
1.8
—
—
—
0
0
0
56
0.00
2.07
0.0
1.0
—
329.63
—
0
38
9
204
0.43
1.98
17.1
10.2
—
—
—
0
0
5
11
4.57
1.94
1.2
1.1
—
—
—
0
0
408
3714
1.22
1.92
4.6
4.7
44.00
905.97
e6/l
1.00
11
64
99
1260
0.75
1.89
1.7
1.8
1177.69
1161.38
nmol/l
0.05
67
947
8
28
2.88
1.86
2.4
2.8
792.88
626.32
u/ml
—
8
28
140
1700
0.78
1.86
3.6
3.9
0.00
0.00
estimate
-0.00
54
542
15
74
2.05
1.76
1.5
1.3
67.50
155.71
au/ml
—
6
23
206
2380
0.81
1.74
3.3
3.4
6.32
6.27
ph
0.25
108
1296
9
195
0.46
1.74
1.1
1.1
—
—
—
0
0
10
40
2.52
1.67
1.1
1.1
2.05
6.60
nmol/l
—
5
8
22
129
1.73
1.58
1.7
1.3
4.08
4.00
mmol/l
0.08
22
122
117
1423
0.79
1.57
3.2
3.7
—
0.00
—
0
17
11
51
2.17
1.51
1.8
1.7
16.60
16.67
%
0.02
11
51
6
22
2.74
1.43
1.3
1.4
—
—
—
0
0
90
1117
0.78
1.43
1.2
1.3
0.96
1.27
u/ml
0.40
14
303
6
23
2.62
1.37
1.7
2.3
—
—
—
0
0
24
151
1.61
1.36
7.2
2.9
1.14
1.76
mg/l
5.15
24
128
5
17
2.95
1.36
1.8
1.8
33.00
53.74
ug/l
—
5
17
10
47
2.14
1.34
1.8
2.1
—
—
—
0
0
12
61
1.98
1.33
2.3
1.2
—
—
—
0
0
32
455
0.69
1.25
2.5
2.6
6.14
6.10
ph
0.10
25
329
43
313
1.40
1.25
3.4
5.7
1.61
1.65
%
0.14
43
301
40
290
1.40
1.20
5.1
5.9
0.78
0.87
%
0.77
40
278
77
619
1.27
1.17
4.0
2.1
60.86
67.08
e9/l
0.91
54
469
19
294
0.64
1.14
2.3
2.4
—
—
—
0
0
12
65
1.86
1.14
1.2
1.2
—
—
—
0
0
8
40
2.01
1.12
1.1
1.3
139.88
102.30
pmol/l
—
8
40
58
454
1.30
1.09
2.4
1.4
—
—
—
0
0
80
653
1.25
1.08
2.3
2.6
9.78
7.47
ug/l
0.33
67
567
75
608
1.26
1.07
2.3
3.4
173.30
270.28
ng/l
2.52
64
565
12
67
1.80
1.05
1.1
1.2
2.33
10.00
u/ml
—
6
34
85
702
1.24
1.04
1.3
1.2
—
—
—
0
0
7
34
2.07
1.03
3.0
3.5
7.94
7.07
mmol/l
—
7
20
9
50
1.81
0.97
1.0
1.2
—
—
—
0
0
9
51
1.77
0.94
1.0
1.2
—
—
—
0
0
6
116
0.51
0.94
1.2
1.3
—
—
—
0
0
10
55
1.83
0.92
1.7
1.6
7.47
8.10
mmol/l
—
10
55
23
324
0.70
0.90
1.0
1.3
—
—
—
0
0
8
43
1.87
0.87
2.5
2.8
—
—
—
0
0
40
513
0.77
0.87
2.6
2.0
0.00
0.00
estimate
—
6
87
146
1642
0.86
0.87
3.3
3.0
0.86
0.78
ug/l
0.50
102
1150
22
153
1.45
0.86
1.0
1.2
—
—
—
0
0
46
577
0.78
0.85
1.9
2.3
181.99
174.49
ug/g
0.06
38
446
6
31
1.94
0.84
1.7
1.2
—
—
—
0
0
8
140
0.57
0.83
1.8
1.9
206.88
207.86
pmol/l
—
8
131
19
130
1.47
0.81
1.5
1.2
—
—
—
0
0
8
47
1.71
0.81
1.3
1.2
—
—
—
0
0
10
58
1.73
0.80
1.2
1.1
—
—
—
0
0
41
516
0.78
0.79
3.1
2.4
0.74
0.34
e6/l
0.50
41
489
56
458
1.24
0.78
2.3
2.1
0.19
0.19
g/l
0.27
56
413
18
257
0.69
0.78
1.3
1.4
—
—
—
0
0
49
395
1.26
0.78
4.5
3.3
24.73
24.10
mmol/l
0.63
49
388
0
27
0.00
0.77
0.0
3.7
—
30.67
—
0
18
0
27
0.00
0.77
0.0
13.4
—
865.78
—
0
27
55
450
1.24
0.77
2.4
2.4
12.16
15.68
nmol/l
2.59
50
403
34
263
1.31
0.74
1.1
1.2
54.76
99.02
u/ml
—
9
104
52
425
1.24
0.74
3.3
3.8
—
—
—
0
0
18
125
1.45
0.73
1.6
1.4
77.69
61.68
mmol/l
0.59
13
100
5
25
2.01
0.72
1.0
1.0
1110.30
1706.56
miu/ml
—
5
25
5
26
1.93
0.70
6.4
1.1
41.32
38.50
g/l
—
5
26
11
169
0.65
0.69
1.7
1.9
39.73
44.31
nmol/l
0.45
11
156
19
135
1.42
0.69
1.9
1.4
26.91
1112.00
e6/l
0.74
11
110
19
135
1.42
0.69
1.9
1.3
34.09
65.78
e6/l
0.26
11
107
30
231
1.31
0.69
1.4
1.8
2.74
7.98
iu/ml
—
9
53
11
69
1.60
0.68
1.7
1.2
—
—
—
0
0
7
119
0.58
0.68
1.1
1.7
—
—
—
0
0
7
121
0.57
0.67
1.1
1.7
—
—
—
0
0
7
121
0.57
0.67
1.1
1.7
—
—
—
0
0
7
121
0.57
0.67
1.1
1.7
—
—
—
0
0
11
70
1.58
0.65
1.1
1.1
0.81
1.97
u/ml
—
6
41
138
1524
0.88
0.64
3.5
3.3
0.00
0.00
estimate
0.80
52
465
521
5371
0.90
0.64
38.9
16.1
43.21
26.90
mg/l
16.06
502
4386
108
961
1.14
0.62
1.8
1.3
2.06
2.74
g/l
2.70
72
555
0
21
0.00
0.60
0.0
1.0
—
19.73
—
0
11
19
254
0.74
0.59
2.2
1.8
3.08
3.41
mmol/l
0.62
12
196
38
309
1.24
0.59
1.2
1.7
2.00
1.50
g/l
1.49
32
269
0
22
0.00
0.59
0.0
1.2
—
139.41
—
0
17
0
22
0.00
0.59
0.0
12.1
—
0.64
—
0
22
0
22
0.00
0.59
0.0
1.0
—
38.39
—
0
10
11
162
0.67
0.59
1.2
1.5
15013.67
12732.22
e6/l
—
6
111
8
53
1.51
0.58
1.1
1.3
—
—
—
0
0
8
53
1.51
0.58
1.1
1.2
32.88
35.60
mmol/l
—
8
47
7
115
0.61
0.58
1.1
1.7
—
—
—
0
0
6
35
1.72
0.57
3.2
1.9
11.17
21.20
nmol/l
—
6
27
6
38
1.58
0.54
1.3
1.8
16.55
14.79
umol/l
—
6
32
6
98
0.61
0.52
1.0
1.8
—
—
—
0
0
22
170
1.30
0.52
4.3
3.0
1.79
1.61
mmol/l
0.33
22
164
82
727
1.14
0.51
4.7
3.5
7.38
7.38
ph
0.16
47
426
5
85
0.59
0.45
1.0
2.0
—
—
—
0
0
11
152
0.72
0.44
1.2
1.2
—
826.00
—
0
5
238
2507
0.93
0.43
2.9
3.0
333.72
138.70
ug/l
4.09
226
2303
8
57
1.41
0.42
1.1
1.2
—
—
—
0
0
20
158
1.27
0.42
3.6
3.6
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
2.84
—
0
7
5
36
1.39
0.38
5.0
2.1
32.20
35.87
mg/l
—
5
30
72
649
1.12
0.38
5.2
2.8
5.18
4.80
e9/l
0.34
61
541
18
143
1.27
0.37
1.5
1.2
—
—
—
0
0
169
1788
0.93
0.35
3.0
3.2
—
—
—
0
0
24
201
1.20
0.32
1.3
1.2
—
—
—
0
0
23
192
1.20
0.32
3.5
1.4
4.15
1.35
ratio
0.46
14
110
179
1701
1.07
0.31
2.0
2.3
3.24
2.83
mg/l
1.34
154
1428
323
3333
0.95
0.31
4.6
3.2
56.90
51.04
u/l
0.56
311
3067
18
147
1.23
0.31
4.8
3.0
7.28
7.27
mmol/l
0.01
18
141
26
222
1.18
0.29
1.8
1.8
—
—
—
0
0
25
213
1.18
0.29
1.9
2.5
220.18
258.41
mg/l
0.23
11
76
10
76
1.32
0.28
1.1
1.0
—
—
—
0
0
395
3854
1.05
0.28
4.5
4.3
—
3.08
—
0
7
34
385
0.88
0.27
1.1
1.2
—
—
—
0
0
14
113
1.24
0.27
1.0
1.2
—
—
—
0
0
17
141
1.21
0.26
1.2
1.1
—
—
—
0
0
5
73
0.68
0.26
2.4
2.7
—
—
—
0
0
5
74
0.67
0.26
1.8
1.2
26.82
91.97
mu/l
—
5
66
46
508
0.90
0.26
1.2
1.4
—
—
—
0
0
258
2501
1.05
0.23
4.8
4.4
34.77
99.26
ng/l
1.53
218
1948
37
333
1.12
0.22
1.5
1.4
—
—
—
0
0
13
107
1.22
0.21
1.1
1.4
184.00
254.77
miu/ml
—
5
49
16
135
1.19
0.21
7.7
9.4
11.06
11.50
mmol/l
0.21
16
127
16
135
1.19
0.21
7.7
9.4
103.38
105.31
mmol/l
0.99
16
127
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
17.46
—
0
11
0
11
0.00
0.21
0.0
8.3
—
7.93
—
0
11
0
11
0.00
0.21
0.0
1.0
—
0.69
—
0
5
0
10
0.00
0.21
0.0
1.3
—
68.40
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
5.90
—
0
10
0
10
0.00
0.21
0.0
1.0
—
8.26
—
0
5
94
888
1.07
0.21
1.4
1.3
22.35
37.79
iu/ml
1.37
22
249
0
13
0.00
0.21
0.0
1.2
—
94.08
—
0
8
6
48
1.25
0.20
4.2
2.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
15
175
0.85
0.19
4.7
2.7
61.17
60.01
%
0.07
15
169
7
63
1.11
0.17
2.7
1.3
—
—
—
0
0
10
119
0.84
0.15
1.1
1.4
—
—
—
0
0
7
86
0.81
0.14
1.1
1.1
—
—
—
0
0
87
833
1.05
0.14
1.3
1.3
23.28
9.53
u/ml
0.48
20
284
33
351
0.94
0.10
1.5
1.7
—
—
—
0
0
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
42
441
0.95
0.09
2.3
3.9
86.14
98.11
ng/l
0.36
34
375
12
134
0.89
0.08
1.9
1.6
—
—
—
0
0
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
12
110
1.09
0.05
1.1
1.2
0.92
0.92
g/l
0.01
12
110
61
602
1.01
0.01
5.7
2.9
4.64
4.41
kpa
0.27
61
577
14
144
0.97
0.00
1.0
1.1
—
—
—
0
0
10
103
0.97
0.00
1.0
1.2
1.42
1.51
g/l
—
10
103
0
8
0.00
-0.00
0.0
1.6
—
3.39
—
0
8
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
3.88
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
38.87
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
170.33
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
354.13
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
74.67
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
9
93
0.97
-0.00
1.0
1.1
28.38
19.95
u/l
—
9
81
9
90
1.00
-0.00
1.1
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
14.2
—
16.34
—
0
5
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
64
0.94
-0.00
1.3
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
49
1.02
-0.00
1.4
1.1
—
285.71
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_HEART_MEDIASTINUM_PLEURA_WIDE – Malignant neoplasm of heart, mediastinum and pleura, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).