Poikiloderma of Civatte

L12_POIKOLOCIVAT

photosensitivity disease: Photosensitivity refers to various symptoms, diseases and conditions caused or aggravated by exposure to sunlight.

Suggest a new description

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L57.3 Cause of death: ICD-10 — L57.3 2 out of 7 registries used, show all original rules.	76
4. Check minimum number of events None	76
5. Include endpoints None	76
6. Filter based on genotype QC (FinnGen only)	70

Control definitions (FinnGen only)

Control exclude: L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L57
Name in latin: Poikiloderm[i]a Civatte

NAME	L12_POIKOLOCIVAT
CONTROL_EXCLUDE	L12_RADIATIONRELATEDSKIN
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L573
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L573
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Poikiloderma of Civatte based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	307	186	121
Only index persons	294	181	113
Unadjusted period prevalence (%)
Whole population	0.00	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	-	54.65	53.29
Only index persons	53.91	54.48	52.99

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	70	50	20
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	54.06	54.01	54.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
72: Matched controls
720

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L57.3

ICD-10 Finland

Poikiloderma of Civatte

+∞

103.5

L57.0

ICD-10 Finland

Actinic keratosis

15.5

11.1

E0000UV, ,

ATC

4.4

8.8

205

L30.9

ICD-10 Finland

Dermatitis, unspecified

4.5

8.5

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

4.8

6.7

D06BX01

ATC

metronidazole; topical

4.9

6.6

-, ,

ICD-10 Finland

20.2

6.4

SPAT1210

SPAT

Application of cast or individual aid

11.5

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

128

3.12

4.99

1.5

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

5.86

4.92

1.5

—

(3019150) Specific gravity of Urine by Refractometry

154

2.78

4.19

5.4

4.4

1.01

1.02

kg/l

0.77

(40761535) Cells panel - Urine sediment

3.54

3.77

4.8

3.6

—

(3037522) Nuclear Ab [Titer] in Serum

103

2.81

3.72

1.3

1.4

170.00

737.39

titre

—

(3000475) Leukocytes [#/volume] in Synovial fluid

7.61

3.45

2.0

1.1

3745.57

656.40

e6/l

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.98

3.22

1.3

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.82

3.21

9.1

7.8

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

7.15

2.92

1.3

1.0

—

(40768443) Skin Pathology biopsy report

4.60

2.77

1.0

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

3.32

2.63

1.5

—

(3000494) Fungus identified in Specimen by Culture

2.52

2.62

1.7

1.4

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

5.84

2.60

1.2

1.3

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.47

2.42

16.1

6.1

102.53

103.64

mmol/l

0.51

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

251

2.09

2.40

2.1

102.09

103.92

pmol/l

0.12

119

(3011397) Hemoglobin [Presence] in Urine by Test strip

145

2.11

2.19

5.4

3.9

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

418

2.17

2.12

2.8

3.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.41

2.10

1.4

2.0

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

3.58

2.02

1.6

1.3

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

3.58

2.02

1.6

1.3

—

(42529406) Shigella sp [Presence] in Stool by Culture

3.58

2.02

1.6

1.3

—

(3029937) Albumin [Presence] in Urine by Test strip

195

1.92

1.88

6.1

3.9

0.00

estimate

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

195

1.92

1.88

2.4

2.2

137.00

109.16

u/l

0.48

186

(46235355) HIV 1 and 2 tests - Meaningful Use set

2.14

1.87

1.5

1.7

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

105

2.10

1.86

2.1

2.7

0.47

1.05

e6/l

1.11

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

3.26

1.85

1.3

1.2

—

79.66

—

(3009261) Glucose [Presence] in Urine by Test strip

346

1.91

1.83

5.6

3.9

0.00

0.07

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

346

1.91

1.83

5.2

3.8

0.00

24.98

estimate

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

122

2.02

1.80

1.6

1.4

—

(3043409) Potassium [Moles/volume] in Arterial blood

3.54

1.78

1.2

3.6

3.67

3.98

mmol/l

—

(3002256) Pathology report gross observation

2.16

1.77

1.6

1.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.11

1.74

1.4

2.1

—

(40768804) Tissue Pathology biopsy report

273

1.83

1.71

3.4

1.9

—

(3023368) Bacteria identified in Blood by Culture

166

1.89

1.69

3.5

3.8

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

3.75

1.64

1.2

1.4

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.87

1.62

1.3

1.8

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

492

2.10

1.62

7.6

4.5

10.73

10.67

mm/h

0.01

459

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

3.17

1.62

1.2

1.3

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

2.66

1.49

1.9

1.1

—

(3018405) Lactate [Moles/volume] in Arterial blood

2.75

1.40

1.2

6.2

0.88

1.52

mmol/l

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

1.39

0.0

1.1

—

1.63

—

(3037467) Urinalysis macro (dipstick) panel - Urine

417

1.76

1.34

5.2

4.2

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.90

1.30

1.6

1.4

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.37

1.29

32.1

6.8

0.55

0.75

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.30

1.26

30.5

6.8

1.21

1.37

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

2.16

1.23

1.2

1.4

—

(3022948) Iron [Moles/volume] in Serum or Plasma

105

1.81

1.19

1.3

2.6

16.09

13.72

umol/l

0.61

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

2.61

1.17

2.0

1.2

—

(3020891) Body temperature

2.47

1.16

2.7

4.0

36.86

36.95

°c

—

(3008898) HLA-B27 [Presence]

2.39

1.14

1.4

1.2

—

(40758558) Short blood count panel - Blood

193

1.64

1.14

7.8

6.9

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.92

1.08

1.3

2.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.03

1.07

1.6

1.7

—

(3026008) Bacteria identified in Urine by Culture

178

1.62

1.06

3.3

2.9

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

226

1.56

1.00

2.8

2.7

55.23

56.86

u/l

0.14

213

(3014007) Fractional oxyhemoglobin in Arterial blood

2.04

1.00

36.7

7.0

93.14

95.11

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

2.33

0.96

1.8

1.4

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

2.33

0.96

1.2

1.4

—

1.91

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.16

0.91

42.2

6.8

25.68

24.96

mmol/l

—

(3025941) Bacteria identified in Stool by Culture

1.97

0.91

2.4

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.92

0.89

1.1

1.5

—

(1761868) Lipid panel - Serum or Plasma

281

0.64

0.89

4.9

3.2

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.88

0.89

1.8

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

1.69

0.86

1.2

2.5

27.25

22.62

0.55

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.75

0.84

1.8

1.6

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

142

1.57

0.84

2.4

1.9

0.95

1.30

mg/l

0.25

119

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

142

1.57

0.84

1.4

1.3

1.40

6.85

u/ml

—

(3030467) Casts [#/volume] in Urine by Automated count

171

1.51

0.79

3.3

2.8

0.07

0.39

e6/l

2.27

126

(3018095) Leukocytes [#/volume] in Urine

236

1.46

0.79

4.8

3.8

11.42

66.26

e6/l

1.14

171

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.67

0.78

1.4

1.5

—

(3015736) pH of Urine

275

1.45

0.77

5.3

3.6

6.44

6.12

0.93

162

(3002582) Erythrocytes [#/volume] in Urine

210

1.46

0.74

4.1

3.0

11.58

26.74

e6/l

1.36

166

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.61

0.73

1.2

2.5

2.29

2.40

g/l

0.28

(3042936) Bacteria identified in Isolate by Culture

1.62

0.72

2.8

2.0

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

490

0.70

0.72

4.8

3.4

44.98

47.90

u/l

0.14

471

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.74

0.71

1.3

4.0

103.29

89.95

ng/l

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.78

0.65

2.8

2.7

0.66

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.71

0.62

2.8

2.7

0.94

1.37

—

(3033658) Prothrombin time (PT) actual/Normal

158

0.64

0.61

15.2

3.8

88.73

94.01

0.41

158

(3019060) Gas panel - Arterial blood

1.83

0.60

4.3

5.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

246

1.38

0.60

4.9

3.6

15.50

34.56

ng/l

1.09

155

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

287

1.35

0.56

2.4

1.9

1.38

1.42

mmol/l

0.10

242

(36304419) Bacteria [Presence] in Urine

164

1.40

0.55

3.2

2.7

—

estimate

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.46

0.54

1.7

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

179

1.33

0.44

4.8

5.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

295

1.29

0.43

3.8

2.7

—

estimate

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.50

0.41

1.2

1.6

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.40

0.0

1.8

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.40

0.0

1.0

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.39

0.0

4.3

—

22.47

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.50

0.37

1.0

3.3

—

(42870588) Differential panel, method unspecified - Blood

203

1.27

0.36

10.2

5.4

—

(3013512) EKG study

223

1.26

0.35

4.5

3.3

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.71

0.33

3.0

1.4

1.47

1.43

—

(3044640) Blood type and Crossmatch panel - Blood

188

1.25

0.30

3.7

2.2

—

(3022145) Colonoscopy Study observation

1.27

0.27

1.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

134

1.25

0.25

4.1

2.2

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

124

0.78

0.24

7.4

4.2

1.81

1.67

ug/l

—

110

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3045716) Anion gap in Serum or Plasma by calculation

0.00

0.21

0.0

2.1

—

9.82

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.21

0.0

1.5

—

89.65

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.21

0.0

1.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.21

0.0

2.0

—

4.97

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.21

0.0

2.0

—

8.93

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.21

0.0

1.1

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.30

0.21

44.3

5.3

1.50

1.51

mmol/l

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3010421) pH of Blood

0.00

0.20

0.0

2.0

—

7.42

—

(4035726) Immunohistochemistry procedure

1.16

0.18

1.9

1.3

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

368

1.13

0.15

7.4

7.6

10.18

10.01

umol/l

0.05

350

(3022096) Basophils/Leukocytes in Blood

310

1.12

0.13

10.8

5.6

0.72

0.71

0.01

292

(3000991) Gas panel - Venous blood

1.15

0.10

53.4

5.8

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.12

0.10

1.0

1.5

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.16

0.09

3.5

2.8

0.20

4.40

e6/l

—

(3012516) Albumin [Mass/volume] in Urine

195

1.11

0.09

3.0

3.2

125.29

38.13

mg/l

—

123

(3002030) Lymphocytes/Leukocytes in Blood

314

1.09

0.09

11.1

5.8

30.65

29.66

0.22

304

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.09

0.08

1.7

1.5

—

(3000492) Spirometry study

1.05

0.08

1.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

167

1.10

0.07

1.4

1.3

0.58

1.73

u/ml

—

(3018010) Neutrophils/Leukocytes in Blood

316

1.08

0.07

11.3

5.7

55.83

55.90

0.01

307

(3003694) ABO and Rh group [Type] in Blood

177

1.02

0.00

1.4

—

(40768797) Stomach Pathology biopsy report

1.01

0.00

1.1

1.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

196

1.03

0.00

3.3

3.8

9.94

5.91

mg/mmol

—

120

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.5

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

4.2

—

2.25

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.0

2.1

—

15.53

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

16.32

—

(3015183) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells

0.00

0.0

1.3

—

8.50

—

(21494815) CD4 cells/Lymphocytes in Specimen

0.00

0.0

1.3

—

39.07

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(44790048) Parainfluenza type 2 nucleic acid detection

0.00

0.0

2.6

—

(3035715) Granulocytes [#/volume] in Blood

0.00

0.0

1.7

—

4.75

—

(44806118) Parainfluenza type 4 nucleic acid detection

0.00

0.0

2.6

—

(1616796) Gas panel - Central venous blood

0.00

0.0

1.4

—

(44790049) Parainfluenza type 3 nucleic acid detection

0.00

0.0

2.6

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.1

—

(44790047) Parainfluenza type 1 nucleic acid detection

0.00

0.0

2.6

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.3

—

(3033306) Mononuclear cells/Leukocytes in Cerebral spinal fluid

0.00

0.0

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

1.0

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.4

—

92.59

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.2

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

2.5

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

168.02

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

63.80

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

2.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

1.9

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.4

—

7.05

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

1.2

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

136.02

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.0

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.2

—

134.73

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

49.14

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

6.8

—

0.80

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.7

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

1.8

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

7.40

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

4.8

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

1.1

—

0.61

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.6

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.1

—

297.24

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.98

-0.00

3.2

2.5

3.16

7.57

ug/l

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.0

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.2

—

6.44

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_POIKOLOCIVAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_POIKOLOCIVAT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_POIKOLOCIVAT – Poikiloderma of Civatte

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Poikiloderma of Civatte

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints