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Acute hepatitis B

EFO Endpoint Browser PheWeb

AB1_HEPATITIS_B

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B16
  • Hospital discharge: ICD-9 — 070[2-3]
  • Cause of death: ICD-10 — B16
  • Cause of death: ICD-9 — 070[2-3]

2 out of 7 registries used, show all original rules.

180

4. Check minimum number of events

None

180

5. Include endpoints

None

180

6. Filter based on genotype QC (FinnGen only)

154

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_HEPATITIS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
B15-B19
Name in latin
Hepatitis B acuta

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1640 629 974
Only index persons 1328 541 787
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 30.79 27.28 32.85
Only index persons 30.02 26.63 32.34

-FinnGen-

Key figures

All Female Male
Number of individuals 154 74 80
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 32.87 28.54 36.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
168
Matched controls
1680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B16.9
ICD-10 Finland
Acute hepatitis B without delta-agent and without hepatic coma
+∞
130.9
108
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
15.8
58.6
60
57
0703A
ICD-9 Finland
Viral hepatitis B without mention of hepatic coma
+∞
55.3
50
*
B18.2
ICD-10 Finland
Chronic viral hepatitis C
+∞
49.4
45
*
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
+∞
30.1
28
*
P19
ICPC
Drug abuse
334.0
28.7
28
*
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
+∞
26.8
25
*
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
112.8
19.0
20
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
37.5
16.1
20
6
N05BA01
ATC
diazepam; systemic, rectal
4.6
14.7
42
114
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
163.6
14.7
15
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.0
14.6
24
39
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
+∞
13.7
13
*
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
151.8
13.7
14
*
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
151.8
13.7
14
*
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
+∞
12.7
12
*
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
+∞
12.7
12
*
F19.21
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances currently independent but staying in a controlling environment
+∞
11.6
11
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.5
10.8
29
74
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
64.2
10.8
12
*
3049X
ICD-9 Finland
Drug dependence, Unspecified drug dependence
+∞
10.5
10
*
N05AH04
ATC
quetiapine; oral
3.2
10.3
55
224
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.7
10.3
38
123
N05CD07
ATC
temazepam; oral
4.1
10.1
31
88
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
105.7
9.5
10
*
F15.3
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, withdrawal state
+∞
9.5
9
*
Z72.2
ICD-10 Finland
Drug use
+∞
9.5
9
*
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
+∞
9.5
9
*
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
+∞
9.5
9
*
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
+∞
9.5
9
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.1
9.4
29
82
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.6
8.8
32
102
A06AD11
ATC
lactulose; oral
3.7
8.7
31
97
P29
ICPC
Psychological sympt/compl other
4.0
8.5
26
73
3044A
ICD-9 Finland
Drug dependence, Amphetamine and other psychostimulant dependence
94.6
8.5
9
*
Z2221
NOMESCO Finland
Medical doctor
2.7
8.4
62
297
0705A
ICD-9 Finland
Viral hepatitis, Other specified viral hepatitis without mention of hepatic coma
+∞
8.4
8
*
B17.1
ICD-10 Finland
Acute hepatitis C
+∞
8.4
8
*
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
+∞
8.4
8
*
D72
ICPC
Viral hepatitis
+∞
8.4
8
*
F19.2
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, dependence syndrome
+∞
8.4
8
*
F19.9
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, unspecified mental and behavioural disorder
+∞
8.4
8
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.0
8.4
19
42
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
5.2
8.3
18
38
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
8.3
34
117
Z71.8
ICD-10 Finland
Other specified counselling
2.6
8.0
74
395
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
47.2
7.8
9
*
F60.2
ICD-10 Finland
Dissocial personality disorder
83.6
7.5
8
*
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
11.6
7.4
13
12
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
+∞
7.3
7
*
F60.9
ICD-10 Finland
Personality disorder, unspecified
10.7
7.2
13
13
N05AH03
ATC
olanzapine; systemic
3.7
7.0
24
73
N05BA02
ATC
chlordiazepoxide; systemic
10.0
6.9
13
14
R4110
NOMESCO Finland
Physiotherapy
2.5
6.8
57
287
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
6.7
33
126
K05.31
ICD-10 Finland
Periodontitis pronounced
3.2
6.7
29
103
Z3231
NOMESCO Finland
Registered nurse
2.5
6.6
53
261
N07BB01
ATC
disulfiram; oral
4.1
6.6
19
51
N06AX11
ATC
mirtazapine; oral
2.3
6.5
71
402
P01AB01
ATC
metronidazole; oral, rectal
2.3
6.4
82
494
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.2
6.3
16
28
P18
ICPC
Medication abuse
27.8
6.3
8
*
F19.00
ICD-10 Finland
Intoxication caused by several drugs in combination or by other psychoactive substances uncomplicated
+∞
6.3
6
*
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
+∞
6.3
6
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
13.2
6.2
10
8
A46
ICD-10 Finland
Erysipelas
2.8
6.1
33
133

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
34
10.95
26.47
1.3
1.2
—
—
—
0
0
56
129
6.01
24.74
2.0
1.6
—
—
—
0
0
33
43
9.31
24.73
11.1
1.7
—
—
—
0
0
81
260
5.08
24.27
2.6
1.7
—
—
—
0
0
29
38
9.02
21.52
1.1
1.1
—
—
—
0
0
68
207
4.84
21.36
2.3
1.8
—
—
—
0
0
20
0
+∞
21.29
2.6
0.0
—
—
—
0
0
85
316
4.42
20.39
2.9
1.9
—
—
—
0
0
26
33
9.14
19.72
1.0
1.1
—
—
—
0
0
31
62
5.91
15.47
1.4
1.3
164.66
277.03
miu/ml
—
10
36
109
555
3.74
15.32
5.8
3.7
110.48
32.95
u/l
1.37
104
530
27
52
6.00
13.96
6.6
1.4
—
—
—
0
0
13
0
+∞
13.73
1.0
0.0
—
—
—
0
0
37
101
4.42
12.78
2.3
1.7
0.31
0.31
mg/l
0.00
17
47
28
65
4.97
11.75
6.9
1.4
—
—
—
0
0
91
479
2.96
10.91
9.7
6.2
—
—
—
0
0
28
70
4.60
10.72
6.9
1.4
—
—
—
0
0
28
70
4.60
10.72
6.9
1.4
—
—
—
0
0
28
70
4.60
10.72
6.9
1.4
—
—
—
0
0
23
31
8.42
10.61
7.3
1.5
—
—
—
0
0
28
71
4.53
10.53
6.8
1.4
—
—
—
0
0
23
50
5.17
10.36
1.3
1.2
—
—
—
0
0
29
77
4.34
10.28
4.7
3.6
24.96
24.47
mmol/l
0.50
29
77
83
437
2.78
9.64
9.2
6.5
—
—
—
0
0
14
9
16.81
9.21
1.1
1.0
—
—
—
0
0
47
189
3.06
8.90
7.5
6.8
0.99
1.01
mmol/l
0.25
47
171
36
127
3.34
8.44
8.4
8.4
—
—
—
0
0
106
663
2.62
8.29
13.7
11.1
0.00
0.00
e9/l
0.50
90
539
14
13
11.62
7.96
1.1
1.0
—
—
—
0
0
92
553
2.47
7.62
2.5
2.0
98.88
94.60
pmol/l
0.44
50
307
47
206
2.78
7.50
4.3
2.7
1.75
2.25
e6/l
0.21
20
98
11
8
14.59
6.99
5.4
1.1
—
—
—
0
0
114
781
2.43
6.71
10.4
7.0
1.81
1.96
e9/l
0.51
97
702
112
763
2.40
6.65
10.5
6.9
0.04
0.04
e9/l
0.17
95
668
112
763
2.40
6.65
10.5
6.9
0.58
0.56
e9/l
0.48
95
669
114
788
2.39
6.47
10.7
7.2
0.20
0.19
e9/l
0.18
96
703
67
371
2.34
6.42
7.3
4.4
—
—
—
0
0
144
1116
3.03
6.31
13.5
8.8
88.21
77.09
u/l
1.00
138
1060
95
613
2.27
6.28
5.3
3.3
6.26
6.19
ph
0.15
51
355
92
595
2.21
5.94
12.5
11.8
1.14
1.16
inr
0.23
74
496
33
135
2.80
5.91
4.5
4.0
1.96
1.85
mmol/l
0.08
33
119
74
440
2.22
5.88
3.3
2.3
—
—
—
0
0
33
136
2.78
5.82
4.4
4.0
7.38
7.39
ph
0.30
21
87
118
848
2.32
5.82
16.3
11.1
4.01
4.02
e9/l
0.01
107
750
73
440
2.17
5.53
4.4
3.1
32.73
170.61
e6/l
0.45
51
331
66
384
2.18
5.45
4.5
2.8
0.19
0.51
e6/l
1.03
42
272
41
196
2.44
5.35
2.3
2.2
—
—
—
0
0
40
191
2.44
5.22
6.0
7.6
104.12
104.10
mmol/l
0.01
40
191
71
437
2.08
4.98
5.0
4.6
7.41
7.40
ph
0.56
50
301
80
515
2.06
4.97
5.5
3.6
86.28
24.58
e6/l
0.42
52
350
141
1127
2.56
4.96
4.9
3.6
80.95
48.65
u/l
0.91
135
1085
96
669
2.01
4.70
7.8
7.8
1.21
1.21
mmol/l
0.28
86
583
55
316
2.10
4.57
3.2
2.0
2.82
2.94
mg/l
0.13
48
274
73
474
1.96
4.27
3.8
3.4
2.33
2.35
mmol/l
0.79
65
436
34
166
2.31
4.18
1.8
1.7
—
—
—
0
0
115
874
2.00
4.18
4.9
4.0
—
273.46
—
0
13
54
319
2.02
4.11
1.9
1.7
1.96
1.22
mg/l
0.42
45
253
108
827
1.86
3.57
7.2
5.1
7.03
6.63
mmol/l
0.53
103
785
66
436
1.85
3.52
3.1
2.6
—
0.22
—
0
9
21
89
2.55
3.48
8.9
7.9
25.73
24.92
mmol/l
0.39
21
89
19
78
2.62
3.35
11.1
10.1
23.96
24.29
mmol/l
0.17
19
78
31
160
2.15
3.32
3.8
1.7
—
—
—
0
0
57
369
1.82
3.19
1.9
1.6
17.37
21.04
nmol/l
1.36
48
319
42
247
1.93
3.16
3.3
2.4
2.45
2.44
mmol/l
0.25
35
224
11
30
3.85
3.15
4.6
2.4
16.50
4.92
u/ml
0.42
11
30
25
122
2.23
3.06
3.3
3.2
5.32
4.50
kpa
1.37
25
122
8
17
4.88
2.95
2.4
1.9
30.89
38.52
%
—
8
17
33
185
1.98
2.83
2.1
1.7
1044.28
1322.78
nmol/l
0.99
25
142
40
240
1.88
2.82
1.2
1.4
213.33
444.29
titre
—
6
56
150
1326
2.22
2.70
5.5
5.2
1.76
1.85
mu/l
0.44
140
1242
67
474
1.69
2.68
7.3
3.2
7.21
8.48
mmol/l
1.54
60
416
42
260
1.82
2.67
5.7
3.3
181.02
288.91
ng/l
0.25
36
174
34
197
1.91
2.65
1.2
1.2
—
—
—
0
0
18
84
2.28
2.45
1.2
1.1
—
—
—
0
0
9
213
0.39
2.41
1.2
1.4
—
—
—
0
0
10
33
3.16
2.40
1.1
1.3
—
—
—
0
0
5
8
6.40
2.39
1.6
2.1
—
—
—
0
0
7
17
4.25
2.38
9.9
4.8
13.03
11.64
mg/l
—
7
17
98
783
1.60
2.32
3.6
3.5
0.00
0.00
estimate
-0.00
13
156
16
73
2.32
2.29
2.4
2.7
167.63
86.80
ng/l
0.50
16
64
52
357
1.66
2.28
1.3
1.4
2.82
2.59
g/l
0.24
37
235
97
778
1.58
2.22
3.6
3.5
0.00
0.00
estimate
-0.00
13
158
98
790
1.58
2.18
3.7
3.5
0.00
0.00
estimate
-0.00
12
146
49
336
1.65
2.15
6.5
3.9
1.01
1.02
kg/l
3.52
38
221
10
37
2.81
2.11
3.6
2.9
0.20
2.86
index
—
5
27
13
56
2.43
2.10
1.5
1.3
—
—
—
0
0
5
11
4.65
1.95
1.0
1.4
—
—
—
0
0
39
258
1.67
1.95
3.1
2.6
507.22
543.91
mosm/kgh2o
0.41
32
219
15
73
2.16
1.87
1.0
1.9
—
12.08
—
0
5
6
18
3.42
1.76
1.0
1.3
—
—
—
0
0
0
47
0.00
1.73
0.0
1.6
—
—
—
0
0
54
701
0.66
1.70
2.6
3.0
—
—
—
0
0
81
658
1.45
1.56
3.4
2.7
—
—
estimate
—
0
0
5
16
3.19
1.45
1.4
1.4
—
—
—
0
0
15
82
1.91
1.41
1.0
2.9
—
—
—
0
0
9
41
2.26
1.39
1.8
1.8
—
—
—
0
0
26
170
1.63
1.36
1.3
1.4
—
—
—
0
0
60
475
1.41
1.28
3.1
2.8
57.64
63.59
u/l
0.28
55
450
159
1513
1.95
1.27
18.1
12.6
—
—
—
0
0
12
63
1.97
1.26
1.0
1.4
—
—
—
0
0
23
149
1.63
1.25
10.3
8.4
7.41
7.42
ph
—
10
92
41
304
1.46
1.24
3.3
2.7
7.87
8.13
e6/l
0.02
35
270
22
142
1.63
1.22
3.0
2.8
1.58
1.75
%
0.49
22
128
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
49
383
1.39
1.11
1.3
1.4
1.57
1.87
u/ml
0.10
16
113
9
50
1.84
0.98
1.1
1.1
—
—
—
0
0
0
32
0.00
0.96
0.0
5.7
—
25.90
—
0
21
6
27
2.27
0.94
1.2
1.2
—
—
—
0
0
67
567
1.30
0.88
2.0
2.0
—
—
—
0
0
8
44
1.86
0.87
2.4
2.2
7.42
7.42
ph
—
8
44
24
175
1.43
0.80
1.8
1.5
—
—
—
0
0
152
1450
1.51
0.79
24.0
14.3
24.29
22.68
mg/l
0.29
136
1155
24
176
1.42
0.78
1.3
1.3
—
—
—
0
0
0
28
0.00
0.77
0.0
4.6
—
—
—
0
0
18
125
1.49
0.76
1.4
1.3
—
—
—
0
0
5
25
2.03
0.73
1.8
2.0
—
—
—
0
0
16
110
1.50
0.71
2.8
2.6
66.04
71.93
e9/l
—
10
81
5
92
0.53
0.69
1.4
3.5
7.42
7.42
ph
—
5
78
5
27
1.88
0.69
1.8
1.4
—
—
—
0
0
5
27
1.88
0.69
1.8
1.4
—
—
—
0
0
5
27
1.88
0.69
1.8
1.4
—
—
—
0
0
5
27
1.88
0.69
1.8
1.4
—
—
—
0
0
13
86
1.55
0.68
1.4
1.3
—
—
—
0
0
23
172
1.39
0.68
1.2
1.2
—
—
—
0
0
7
44
1.62
0.66
1.0
1.1
—
—
—
0
0
7
44
1.62
0.66
1.0
1.1
—
—
—
0
0
136
1424
0.76
0.63
4.3
4.1
1.42
1.32
mmol/l
0.76
129
1337
40
331
1.27
0.61
4.2
2.6
—
—
—
0
0
10
67
1.52
0.51
1.1
1.2
—
—
—
0
0
146
1408
1.28
0.46
5.0
4.6
6.20
5.89
mmol/l
1.10
136
1318
7
50
1.42
0.45
1.4
1.2
—
—
—
0
0
117
1109
1.18
0.41
4.4
4.4
14.40
14.57
pmol/l
0.37
111
1033
0
16
0.00
0.41
0.0
3.3
—
1.18
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
33.65
—
0
17
0
19
0.00
0.39
0.0
1.6
—
1.00
—
0
10
11
81
1.38
0.37
3.9
2.9
0.55
0.63
%
0.71
11
81
5
76
0.65
0.36
1.0
1.1
1.61
1.50
g/l
—
5
76
14
178
0.77
0.36
1.6
1.6
—
—
—
0
0
5
78
0.63
0.36
1.0
1.2
0.82
0.89
g/l
—
5
78
11
82
1.37
0.35
3.9
2.9
1.83
1.37
%
0.51
11
82
49
441
1.16
0.33
1.8
1.5
—
—
—
0
0
6
47
1.29
0.32
1.7
3.1
1.32
1.39
mg/l
—
6
42
7
99
0.69
0.31
1.3
1.9
—
—
—
0
0
14
111
1.29
0.31
4.5
3.1
—
—
—
0
0
13
102
1.30
0.31
2.2
4.2
7.47
7.32
ph
—
8
72
145
1484
0.83
0.29
5.0
4.8
1.34
1.44
mmol/l
2.06
138
1399
8
63
1.28
0.28
1.9
2.1
—
—
—
0
0
35
391
0.87
0.27
5.7
5.5
—
—
—
0
0
35
313
1.15
0.26
1.3
1.3
75.97
33.45
iu/ml
—
6
94
18
153
1.20
0.23
2.1
2.1
391.00
380.80
nmol/l
0.08
18
142
0
11
0.00
0.21
0.0
1.1
—
211.95
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.6
—
611.20
—
0
5
0
12
0.00
0.21
0.0
1.8
—
74.67
—
0
12
11
90
1.24
0.19
4.2
4.2
4.79
4.61
pmol/l
0.25
11
79
7
59
1.19
0.18
2.0
1.5
—
4.48
—
0
14
31
288
1.09
0.13
1.4
1.3
22.47
10.62
u/ml
—
7
112
11
125
0.87
0.10
1.2
1.2
—
24.87
—
0
9
5
44
1.14
0.10
1.4
1.3
—
—
—
0
0
147
1486
0.91
0.09
5.1
4.9
4.61
4.72
mmol/l
0.59
139
1415
5
64
0.77
0.08
1.2
4.2
—
—
—
0
0
44
458
0.95
0.08
3.3
2.9
0.00
0.01
estimate
0.50
11
123
7
68
1.03
0.08
2.1
4.1
25.99
24.57
mmol/l
—
7
68
8
78
1.03
0.07
2.4
4.8
—
—
—
0
0
9
85
1.06
0.07
5.1
2.6
5.60
6.02
ug/l
—
9
80
21
224
0.93
0.07
1.4
1.4
—
—
—
0
0
50
516
0.96
0.06
3.9
4.7
1.55
2.29
ug/l
0.57
43
469
151
1499
1.07
0.05
5.8
5.3
2.74
2.81
mmol/l
0.41
143
1419
62
608
1.03
0.04
3.5
3.4
0.00
0.00
estimate
—
10
133
43
439
0.97
0.02
5.0
3.4
90.45
68.81
mg/l
0.25
31
281
12
113
1.07
0.02
2.2
3.3
0.07
0.15
e6/l
0.62
12
105
31
316
0.98
0.00
2.5
2.9
0.57
0.73
ug/l
0.57
19
177
11
111
0.99
0.00
1.3
1.1
—
—
—
0
0
43
426
1.01
0.00
3.6
3.6
0.00
0.02
estimate
0.50
11
144
45
454
0.99
0.00
6.0
4.0
14.43
11.81
mg/mmol
0.17
31
281
12
123
0.97
0.00
1.7
1.8
—
0.00
estimate
—
0
28
13
133
0.98
0.00
1.2
1.2
—
—
—
0
0
52
517
1.01
0.00
3.2
3.6
14.42
29.73
ng/l
2.04
28
328
13
135
0.96
0.00
2.3
2.3
—
13.80
—
0
11
0
7
0.00
0.00
0.0
1.3
—
2456.43
—
0
7
0
7
0.00
0.00
0.0
1.1
—
176.95
—
0
7
0
7
0.00
0.00
0.0
2.6
—
52.50
—
0
7
0
7
0.00
0.00
0.0
1.4
—
0.00
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
28.43
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
6
0.00
-0.00
0.0
2.8
—
5.58
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
28.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
11.40
—
0
5
0
6
0.00
-0.00
0.0
3.0
—
0.81
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.6
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
2.82
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1091.00
—
0
8
9
90
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.8
—
17.50
—
0
8
0
9
0.00
-0.00
0.0
9.1
—
7.79
—
0
9
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_HEPATITIS_B and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
AB1_HEPATITIS_B 3.56 [2.5, 5.06] < 0.001
Birth year 0.986 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 128 out of 555 males with AB1_HEPATITIS_B died.

Mortality risk

Mortality risk for people of age

years, who have AB1_HEPATITIS_B.

N-year risk Females Males
1 No data 0.522%
5 No data 4.322%
10 No data 10.091%
15 No data 17.924%
20 No data 29.368%

Relationships between endpoints

↥

Index endpoint: AB1_HEPATITIS_B – Acute hepatitis B

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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