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Disorder of the sleep-wake schedule

EFO Endpoint Browser PheWeb

F5_SLEEPWAKE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F51.2, G47.2
  • Hospital discharge: ICD-9 — 3074F
  • Cause of death: ICD-10 — F51.2, G47.2
  • Cause of death: ICD-9 — 3074F

2 out of 7 registries used, show all original rules.

807

4. Check minimum number of events

None

807

5. Include endpoints

None

807

6. Filter based on genotype QC (FinnGen only)

711

Control definitions (FinnGen only)

Control exclude
F5_SLEEP

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6901 3035 3847
Only index persons 5380 2449 2931
Unadjusted period prevalence (%)
Whole population 0.10 0.09 0.11
Only index persons 0.10 0.09 0.11
Median age at first event (years)
Whole population 17.72 18.07 17.36
Only index persons 23.48 23.54 23.43

-FinnGen-

Key figures

All Female Male
Number of individuals 711 395 316
Unadjusted period prevalence (%) 0.14 0.14 0.14
Median age at first event (years) 43.22 39.86 47.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
749
Matched controls
7490
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F51.0
ICD-10 Finland
Nonorganic insomnia
+∞
316.9
281
*
G47.2
ICD-10 Finland
Disorders of the sleep-wake schedule
7075.5
307.7
384
*
F51.2
ICD-10 Finland
Nonorganic disorder of the sleep-wake schedule
823.4
307.7
347
8
N05AH04
ATC
quetiapine; oral
6.9
144.3
318
726
N06AX11
ATC
mirtazapine; oral
5.8
128.5
395
1201
G47.3
ICD-10 Finland
Sleep apnoea
6.0
125.4
331
878
N06AX12
ATC
bupropion; oral
7.1
99.3
173
303
G47.9
ICD-10 Finland
Sleep disorder, unspecified
13.5
93.4
92
77
IAB13
NOMESCO Finland
Psychiatric sleep disorder consultation
1006.6
92.9
89
*
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
15.1
81.2
74
54
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.1
79.3
210
535
N06AX16
ATC
venlafaxine; oral
5.0
77.4
210
545
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.9
76.0
213
567
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
15.5
75.9
68
48
P06
ICPC
Sleep disturbance
4.9
69.3
183
461
N06AX22
ATC
agomelatine; oral
14.9
68.0
62
45
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
8.6
67.3
91
118
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
7.4
65.8
103
158
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
6.0
65.6
129
250
N05CF01
ATC
zopiclone; oral
3.9
65.4
280
1005
N06AX05
ATC
trazodone; oral
14.0
64.7
61
47
N05CF02
ATC
zolpidem; oral
4.4
59.9
185
523
N05BA04
ATC
oxazepam; oral
3.6
58.5
266
984
F61.0
ICD-10 Finland
Mixed personality disorders
13.7
57.7
55
43
F34.1
ICD-10 Finland
Dysthymia
8.1
57.4
81
110
IEY18
NOMESCO Finland
Psychiatric sleep coaching, individual
602.0
57.4
56
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
6.6
57.0
99
169
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
6.1
56.9
109
205
G47.0
ICD-10 Finland
Disorders of initiating and maintaining sleep [insomnias]
+∞
55.9
53
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.5
54.6
155
409
N06AB10
ATC
escitalopram; oral
3.5
53.9
259
985
N06AX21
ATC
duloxetine; oral
4.6
52.9
147
381
N06AB06
ATC
sertraline; oral
4.1
51.9
169
493
N06AB04
ATC
citalopram; systemic
3.8
51.7
201
664
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
6.0
50.9
97
181
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
21.0
49.8
38
19
N06AB03
ATC
fluoxetine; oral
4.2
49.4
155
439
ZY010
NOMESCO Finland
Hospital outpatient
4.9
47.6
115
265
N03AX16
ATC
[U] pregabalin
3.4
45.8
207
748
N05AH03
ATC
olanzapine; systemic
4.9
45.4
111
258
N06AX26
ATC
vortioxetine; oral
4.5
44.9
123
313
R53
ICD-10 Finland
Malaise and fatigue
3.0
42.6
268
1170
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.6
42.2
171
574
3074F
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Specific disorders of sleep of nonorganic origin[UNIVALVERYTMIN HÄIRIÖ]
+∞
42.1
40
*
N06BA04
ATC
methylphenidate; oral
4.5
41.6
111
276
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
6.4
41.6
73
125
Z2445
NOMESCO Finland
Psychologist
5.0
41.4
96
213
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
5.0
40.4
94
209
F90.0
ICD-10 Finland
Disturbance of activity and attention
4.3
40.2
117
311
P03
ICPC
Feeling depressed
3.5
39.7
168
578
N06AX03
ATC
mianserin; oral
7.5
39.1
58
83
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.3
38.6
112
297
N03AX09
ATC
lamotrigine; oral
4.8
37.6
92
213
R5140
NOMESCO Finland
Monitoring the use of the aid
3.9
37.5
125
366
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
7.1
36.6
57
86
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.8
35.6
86
197
N05AX12
ATC
aripiprazole; systemic
4.9
35.4
83
185
IBA03
NOMESCO Finland
Psychotherapy evaluation
9.6
35.1
42
46
N05BA01
ATC
diazepam; systemic, rectal
3.7
34.9
127
394
N03AE01
ATC
clonazepam; systemic
5.5
34.9
71
140
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
7.1
33.5
52
78
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
6.6
33.5
56
91
P76
ICPC
Depressive disorder
3.9
33.5
110
318
N06AB05
ATC
paroxetine; oral
5.1
33.4
75
161
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
4.9
33.0
78
175
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
5.5
32.2
65
127
F41.1
ICD-10 Finland
Generalized anxiety disorder
4.0
32.1
100
278
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.9
32.0
75
167
N06AA09
ATC
amitriptyline; systemic
4.5
31.8
84
206
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
7.2
31.3
48
71
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
4.6
30.3
76
179
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.1
30.0
147
546
IGY02
NOMESCO Finland
Psychiatric monitoring contact
4.4
29.6
78
191
N06BA12
ATC
lisdexamfetamine; oral
7.1
29.2
45
67
N05AA02
ATC
levomepromazine; systemic
5.8
29.1
55
101
N04BC05
ATC
pramipexole; oral
4.5
27.5
71
171
M79.7
ICD-10 Finland
Fibromyalgia
6.2
27.3
48
82
F51
ICD-10 Finland
Nonorganic sleep disorders
5.6
26.9
53
101
XG466
NOMESCO Finland
Sleep oxymetry
6.7
26.7
43
67
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
7.2
26.5
40
58
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
10.7
26.4
29
28
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.9
26.0
82
229
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.8
25.9
85
244
R06.5
ICD-10 Finland
Mouth breathing
3.3
25.9
108
363
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
6.2
25.9
45
76
Z2446
NOMESCO Finland
Social worker
3.4
25.9
102
331
N03AX12
ATC
[U] gabapentin; oral
3.0
25.7
134
513
P29
ICPC
Psychological sympt/compl other
3.1
25.4
124
457
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
6.9
24.9
39
59
P01
ICPC
Feeling anxious/nervous/tense
2.6
24.8
187
864
F33
ICD-10 Finland
Recurrent depressive disorder
6.1
24.7
44
76
N03AG01
ATC
valproic acid; systemic, rectal
3.8
24.6
80
228
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.0
24.6
73
195
N05CD07
ATC
temazepam; oral
3.8
24.0
78
222
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
6.1
23.8
42
72
IGY99
NOMESCO Finland
Other psychiatric treatment contact
4.6
23.4
58
135
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.6
23.2
82
247
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.7
23.0
55
124
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.7
22.8
76
220
N05AF03
ATC
chlorprothixene; systemic
6.3
22.7
39
65
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
22.5
210
1064
ZYC01
NOMESCO Finland
Remote contact by phone
3.5
22.1
81
250
F60.9
ICD-10 Finland
Personality disorder, unspecified
8.8
22.0
28
33
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.4
21.9
85
272
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
4.6
21.9
54
125
F41.09
ICD-10 Finland
UNS Panic Syndrome
4.7
21.8
52
117
P74
ICPC
Anxiety disorder/anxiety state
3.6
21.6
76
228
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
5.6
21.6
42
79
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
6.6
21.5
35
55
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
8.5
21.5
28
34
A04
ICPC
Weakness/tiredness general
2.5
21.1
159
730
C07AA05
ATC
propranolol; systemic
2.4
20.9
184
905
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.8
20.6
47
102
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.7
20.5
69
201
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
20.4
314
1928
WX722
NOMESCO Finland
PEEP
4.3
20.2
54
133
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.5
20.1
72
219
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
7.5
20.0
29
40
R40.0
ICD-10 Finland
Somnolence
36.9
19.9
25
7
P99
ICPC
Psychological disorders other
4.3
19.8
53
131
N05AX08
ATC
risperidone; systemic
3.2
19.7
83
279
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.8
19.5
110
436
A02BC02
ATC
pantoprazole; systemic
2.0
19.5
465
3326
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.8
19.5
61
169
F39
ICD-10 Finland
Unspecified mood [affective] disorder
5.8
19.3
36
65
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.1
19.3
87
305
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
19.2
184
935
WX723
NOMESCO Finland
CPAP therapy
4.2
19.1
52
130
R51.80
ICD-10 Finland
Headache
2.4
18.7
160
775
A02BC05
ATC
esomeprazole; systemic
2.0
18.5
275
1654
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
18.3
59
167
R03AC02
ATC
salbutamol; inhalant
2.0
18.2
447
3196
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
18.2
321
2049
F32.1
ICD-10 Finland
Moderate depressive episode
3.1
18.0
78
267
E66.8
ICD-10 Finland
Other obesity
3.5
17.9
63
189
Z3231
NOMESCO Finland
Registered nurse
2.1
17.7
228
1299
F41.8
ICD-10 Finland
Other specified anxiety disorders
4.0
17.6
52
138
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
4.2
17.4
47
117
N02AX02
ATC
tramadol; systemic, rectal
2.0
17.1
283
1760
N05BE01
ATC
buspirone; oral
4.8
16.7
38
82
E66.01
ICD-10 Finland
Obesity due to excess calories
2.7
16.6
98
397
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
16.4
154
772
N06AA06
ATC
trimipramine; systemic
6.7
16.3
26
40
N06AG02
ATC
moclobemide; oral
4.7
16.3
38
84
SPAT1240
SPAT
Therapeutic discussion
2.5
15.9
114
507
R06.0
ICD-10 Finland
Dyspnoea
2.1
15.8
192
1063
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.8
15.7
83
317
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
15.6
179
970
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
6.6
15.5
25
39
N06AA12
ATC
doxepin; systemic
4.2
15.4
42
105
C03CA01
ATC
furosemide; systemic
2.2
15.4
146
733
R52.2
ICD-10 Finland
Other chronic pain
4.2
15.3
41
101
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.7
15.3
86
339
D01
ICPC
Abdominal pain/cramps general
2.3
15.3
132
637
F32
ICD-10 Finland
Depressive episode
3.2
15.3
64
214
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
3.9
15.1
46
125
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.3
15.0
59
190
OAA68, ,
SPAT
6.7
15.0
24
37
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
6.9
14.9
23
34
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.4
14.9
113
515
N02BF02
ATC
pregabalin; oral
3.1
14.7
63
214
L28
ICPC
Limited function/disability (L)
2.4
14.7
115
532
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.5
14.6
52
157
G47.8
ICD-10 Finland
Other sleep disorders
4.6
14.6
35
79
Z71.8
ICD-10 Finland
Other specified counselling
1.9
14.6
299
1970
G44.2
ICD-10 Finland
Tension-type headache
2.3
14.5
120
569
F31.8
ICD-10 Finland
Other bipolar affective disorders
4.5
14.4
36
84
A06AD11
ATC
lactulose; oral
2.6
14.2
92
389
J31.0
ICD-10 Finland
Chronic rhinitis
2.6
14.2
89
371
N05AN01
ATC
lithium; oral
4.6
14.1
34
77
L01
ICPC
Neck symptom/complaint
2.2
14.1
143
736
WX780
NOMESCO Finland
Remote monitoring CPAP
3.6
14.1
47
136
L03
ICPC
Low back symptom/complaint
1.9
14.0
236
1457
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.2
13.9
29
58
R01AD09
ATC
mometasone; nasal
1.8
13.9
360
2538
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
6.4
13.8
23
37
C07AB07
ATC
bisoprolol; oral
1.9
13.7
267
1723
IEV99
NOMESCO Finland
Other psychiatric network intervention
6.6
13.7
22
34
R03BA05
ATC
fluticasone; inhalant
2.0
13.7
168
929
M79.6
ICD-10 Finland
Pain in limb
1.8
13.6
313
2125
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
5.6
13.6
26
48
G47.1
ICD-10 Finland
Disorders of excessive somnolence [hypersomnias]
+∞
13.6
13
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
13.5
116
557
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
4.4
13.5
34
80
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
4.8
13.4
30
64
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
13.4
256
1642
D11
ICPC
Diarrhoea
2.2
13.2
125
626
L17
ICPC
Foot/toe symptom/complaint
1.9
13.1
236
1484
R52.9
ICD-10 Finland
Pain, unspecified
2.4
13.0
92
405
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.0
12.9
58
202
E66.00
ICD-10 Finland
Metabolic syndrome
3.2
12.9
51
165
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
12.9
184
1071
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.0
12.8
60
214
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
5.5
12.8
25
47
A02BC03
ATC
lansoprazole; oral
2.0
12.8
170
965
F40.1
ICD-10 Finland
Social phobias
3.6
12.7
43
126
N06BA07
ATC
modafinil; oral
17.7
12.6
19
11
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.9
12.5
212
1305
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.8
12.2
37
100
Z2221
NOMESCO Finland
Medical doctor
1.9
12.2
205
1256
F43.1
ICD-10 Finland
Post-traumatic stress disorder
3.7
12.1
39
110
N05BA12
ATC
alprazolam; oral
2.6
12.1
71
286
IBB03
NOMESCO Finland
Assessment of vocational rehabilitation needs in a mental health context
13.7
12.0
20
15
K59.09
ICD-10 Finland
Constipation, unspecified
2.9
12.0
56
200
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
11.8
87
391
ZY000
NOMESCO Finland
Hospital inpatient
5.0
11.8
25
51
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.5
11.6
75
317
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
11.3
169
993
H03AA01
ATC
levothyroxine sodium; systemic
2.0
11.3
151
855
IGY02, ,
SPAT
5.0
11.3
24
49
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
11.2
183
1107
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.0
11.2
32
83
D06
ICPC
Abdominal pain localized other
2.4
11.2
82
367
ICB06, ,
NOMESCO Finland
5.4
11.1
22
42
IER01
NOMESCO Finland
Psychoeducation, group
5.8
11.1
20
35
A02BA02
ATC
ranitidine; systemic
2.2
11.0
103
511
F51.8
ICD-10 Finland
Other nonorganic sleep disorders
14.2
11.0
18
13
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
11.0
87
403
DHB50
NOMESCO Finland
Turbinoplasty
3.8
11.0
33
89
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.0
193
1195
IER05
NOMESCO Finland
Rehabilitative psychiatric group intervention, social skills
44.0
10.9
13
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
10.9
69
288
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.2
10.9
100
493
M54.5
ICD-10 Finland
Low back pain
1.7
10.8
260
1763
A01
ICPC
Pain general/multiple sites
2.4
10.7
79
354
Z3226
NOMESCO Finland
Physiotherapist
2.0
10.7
135
749
R02
ICPC
Shortness of breath/dyspnoea
2.2
10.6
99
490
R03DC03
ATC
montelukast; oral
2.0
10.6
137
766
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
4.5
10.6
26
60
J02AC01
ATC
fluconazole; systemic
1.7
10.6
257
1744
Z29
ICPC
Social problem NOS
3.9
10.6
31
82
F50.9
ICD-10 Finland
Eating disorder, unspecified
5.1
10.6
22
44
M79.1
ICD-10 Finland
Myalgia
2.0
10.4
127
695
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
5.5
10.4
20
37
F51.1
ICD-10 Finland
Nonorganic hypersomnia
+∞
10.4
10
*
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
10.3
157
926
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
10.3
135
758
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
10.3
298
2117
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.0
10.2
29
75
D93
ICPC
Irritable bowel syndrome
5.4
10.2
20
38
H02AB06
ATC
prednisolone; systemic
1.7
10.1
305
2186
Z01.2
ICD-10 Finland
Dental examination
1.6
10.1
393
3005
IGV01
NOMESCO Finland
Psychiatric network contact
4.1
10.1
28
71
T83
ICPC
Overweight
4.1
10.1
28
71
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.7
10.1
57
225
R11
ICD-10 Finland
Nausea and vomiting
2.3
10.1
78
357
T82
ICPC
Obesity
3.1
10.0
43
146
N05BA06
ATC
lorazepam; systemic, sublingual
3.1
10.0
42
141
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
10.0
144
835
K07.60
ICD-10 Finland
Snapping jaw
2.7
9.9
55
215
Z02.7
ICD-10 Finland
Issue of medical certificate
2.5
9.9
66
283
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.1
9.8
100
513
F84.5
ICD-10 Finland
Asperger syndrome
7.5
9.8
22
30
R06AE07
ATC
cetirizine; oral
1.6
9.8
329
2421
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
9.6
280
1983
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
11.6
9.6
17
15
TAB00
NOMESCO Finland
Lumbar puncture
2.9
9.6
46
167
SPAT1307
SPAT
Psychosocial counselling and guidance
2.2
9.6
80
379
S29
ICPC
Skin symptom/complaint other
1.8
9.5
154
924
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
9.5
88
434
N05AB03
ATC
perphenazine; systemic, rectal
3.7
9.5
30
84
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
7.7
9.5
21
28
F51.3
ICD-10 Finland
Sleepwalking [somnambulism]
+∞
9.4
9
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
4.0
9.4
26
66
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
9.4
147
874
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
4.8
9.3
21
45
L29
ICPC
Musculoskeletal sympt/complt other
2.4
9.3
69
310
R96
ICPC
Asthma
2.3
9.3
74
343
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
9.7
9.3
18
19
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.9
9.3
43
153
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
9.2
64
279
F41.00
ICD-10 Finland
Moderate panic disorder
4.2
9.2
24
58
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.8
9.2
28
76
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.8
9.2
28
76
H02AB07
ATC
prednisone; oral
2.2
9.2
83
406
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
9.2
298
2164
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
9.2
225
1521
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.4
9.1
32
96
D07AC01
ATC
betamethasone; topical
1.7
9.1
244
1688
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
9.1
62
269
A02BC01
ATC
omeprazole; systemic
1.8
9.0
168
1051
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
9.0
180
1149
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.0
9.0
40
139
M02AA10
ATC
ketoprofen; topical
2.1
9.0
92
472
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
9.0
96
501
P20
ICPC
Memory disturbance
2.4
8.9
60
258
F41.3
ICD-10 Finland
Other mixed anxiety disorders
4.0
8.9
25
64
A28
ICPC
Limited function/disability NOS
2.1
8.9
89
452
SPAT1051
SPAT
Guidance regarding sleep disorders
4.6
8.9
21
47
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.0
8.9
19
39
IHZ05, ,
SPAT
2.4
8.9
60
259
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.8
8.8
44
163
D02
ICPC
Abdominal pain epigastric
2.5
8.8
58
247
U07
ICPC
Urine symptom/complaint other
2.4
8.8
62
273
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.7
8.8
47
181
F32.0
ICD-10 Finland
Mild depressive episode
3.5
8.7
30
89
R06AX22
ATC
ebastine; oral
1.9
8.7
122
700
Z07
ICPC
Education problem
4.8
8.6
19
40
M25.5
ICD-10 Finland
Pain in joint
1.6
8.6
234
1620
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.7
8.6
46
177
R03BA02
ATC
budesonide; inhalant
1.8
8.6
134
794
F60.5
ICD-10 Finland
Anankastic personality disorder
7.1
8.6
20
29
L02
ICPC
Back symptom/complaint
2.0
8.6
92
480
A02BA03
ATC
famotidine; systemic
4.1
8.6
23
57
A10BJ02
ATC
liraglutide; parenteral
3.9
8.6
25
66
SPAT1243
SPAT
Psychiatric/psychological examination
3.1
8.6
36
121
R4110, ,
SPAT
2.1
8.6
89
459
N03AX11
ATC
topiramate; oral
3.4
8.6
30
90
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
8.5
85
433
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
8.4
120
691
ZXY83
NOMESCO Finland
Social worker in multidisciplinary team
12.9
8.4
14
11
IDY30, ,
NOMESCO Finland
+∞
8.3
8
*
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
10.9
8.3
15
14
N05AB01
ATC
dixyrazine; systemic
9.6
8.3
16
17
N06AB08
ATC
fluvoxamine; oral
3.9
8.3
24
63
M01AB05
ATC
diclofenac; systemic, rectal
1.6
8.3
420
3359
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
8.2
331
2510
F93.89
ICD-10 Finland
Other childhood emotional disorders
4.0
8.2
23
59
A99
ICPC
Disease/condition unspecnature/site
2.1
8.2
79
396
N02BE01
ATC
paracetamol; systemic, rectal
1.8
8.2
617
5430
WZC00, ,
SPAT
1.8
8.1
126
744
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.5
8.1
28
83
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
8.1
100
548
SPAT1153
SPAT
Removal of sutures
1.7
8.1
180
1181
N02BF01
ATC
gabapentin; oral
2.2
8.1
69
330
IEY01
NOMESCO Finland
Psychoeducation, individual
6.4
8.1
20
32
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
8.0
73
358
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.2
8.0
70
338
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
8.0
99
544
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
7.9
90
479
D04
ICPC
Rectal/anal pain
4.5
7.9
19
43
M03BX02
ATC
tizanidine; oral
1.6
7.9
403
3212
SPAT1238
SPAT
Brief therapy
4.0
7.9
22
56
N29
ICPC
Neurological sympt/complt other
4.7
7.9
18
39
G43.9
ICD-10 Finland
Migraine, unspecified
2.2
7.9
65
306
SPAT1053
SPAT
Memory test
2.4
7.8
56
248
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
7.8
121
714
K59.0
ICD-10 Finland
Constipation
2.6
7.8
44
174
3051, ,
Kela drug reimbursment
7.1
7.8
18
26
C09CA06
ATC
candesartan; oral
1.7
7.8
146
912
IGP01
NOMESCO Finland
Psychiatric family contact
3.6
7.8
25
71
XF402
NOMESCO Finland
ECG with work load test
2.3
7.7
61
282
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.5
7.7
47
193
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
4.4
7.7
19
44
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
7.7
136
835
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.9
7.7
36
129
M70.6
ICD-10 Finland
Trochanteric bursitis
2.1
7.7
74
371
AA1AD
NOMESCO Finland
CT of head and brain
1.7
7.6
152
966
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.3
7.6
28
87
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.1
7.6
32
108
F32.8
ICD-10 Finland
Other depressive episodes
4.2
7.6
20
49
F45.8
ICD-10 Finland
Other somatoform disorders
2.2
7.6
66
318
L16
ICPC
Ankle symptom/complaint
1.9
7.6
104
591
J01FA06
ATC
roxithromycin; oral
1.6
7.5
236
1683
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
7.5
93
511
R25.1
ICD-10 Finland
Tremor, unspecified
3.6
7.5
24
68
F51.5
ICD-10 Finland
Nightmares
80.9
7.4
8
*
P81
ICPC
Hyperkinetic disorder
3.8
7.4
22
59
R4110
NOMESCO Finland
Physiotherapy
1.6
7.4
184
1239
UJF32
NOMESCO Finland
Coloscopy
1.7
7.4
142
893
L12
ICPC
Hand/finger symptom/complaint
1.7
7.3
139
870
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
9.5
7.3
14
15
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.9
7.3
21
55
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
7.3
554
4788
A07AA02
ATC
nystatin; oral
2.7
7.3
37
139
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.1
7.3
72
365
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
7.2
233
1668
ICC03
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric ward
15.9
7.2
11
7
R21
ICPC
Throat symptom/complaint
1.6
7.2
221
1563
SPAT1310
SPAT
Counselling related to known health issue
1.6
7.2
232
1660
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.2
7.2
28
90
N07BB01
ATC
disulfiram; oral
2.8
7.2
34
123
ZXY80
NOMESCO Finland
Doctor in multidisciplinary team
8.0
7.1
15
19
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
7.1
136
853
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
7.1
298
2261
ZXY03
NOMESCO Finland
Occupational therapist
12.2
7.1
12
10
R01AD58
ATC
fluticasone, combinations; nasal
1.6
7.1
198
1370
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
8.9
7.1
14
16
J34.2
ICD-10 Finland
Deviated nasal septum
2.4
7.0
47
202
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
7.0
119
721
SPAT1395
SPAT
Health check-up of persons outside student and working life
3.5
7.0
24
71
A97
ICPC
No disease
1.7
7.0
163
1078
N02CC04
ATC
rizatriptan; oral
2.4
7.0
47
203
N01
ICPC
Headache
1.7
7.0
130
810
A07DA03
ATC
loperamide; oral
3.6
6.9
22
62
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.1
6.9
64
317
SPAT1298
SPAT
Other function in accordance with nutritional therapy nomenclature
8.4
6.8
14
17
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
6.8
214
1519
ZXC60
NOMESCO Finland
Application of heat
4.2
6.8
18
44
Z01.7
ICD-10 Finland
Laboratory examination
1.7
6.8
122
750
J01FA09
ATC
clarithromycin; systemic
1.6
6.8
214
1520
IEY03
NOMESCO Finland
Vocational rehabilitation
11.1
6.8
12
11
R4140
NOMESCO Finland
Psychotherapy
9.4
6.8
13
14
J96.1
ICD-10 Finland
Chronic respiratory failure
5.7
6.8
18
32
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.6
6.8
38
150
IFA37
NOMESCO Finland
Ketamine treatment
40.4
6.8
8
*
R01AD08
ATC
fluticasone; nasal
1.6
6.8
195
1358
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
4.0
6.7
19
49
K02.1
ICD-10 Finland
Caries of dentine
1.5
6.7
469
3938
N05AE04
ATC
ziprasidone; systemic
7.3
6.7
15
21
R05
ICPC
Cough
1.6
6.7
186
1283
G47.4
ICD-10 Finland
Narcolepsy and cataplexy
22.7
6.7
9
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
6.7
120
739
R42
ICD-10 Finland
Dizziness and giddiness
1.7
6.7
126
787
N06AX18
ATC
reboxetine; oral
6.5
6.7
16
25
XA800
NOMESCO Finland
Neuropsychological investigation
2.5
6.6
42
176
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
7.9
6.6
14
18
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.4
6.6
45
195
J45
ICD-10 Finland
Asthma
2.0
6.6
72
378
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.4
6.6
43
183
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
6.6
65
329
M03BC51
ATC
orphenadrine, combinations; systemic
1.6
6.6
165
1110
SPAT1197
SPAT
Extensive health check-up of expecting family
0.4
6.5
33
772
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
6.5
548
4772
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.0
6.5
68
352
IEP99
NOMESCO Finland
Other psychiatric family intervention
5.8
6.5
17
30
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
6.5
190
1327
N06AA10
ATC
nortriptyline; systemic
4.0
6.5
18
46
R73.0
ICD-10 Finland
Abnormal glucose tolerance test
3.5
6.5
22
65
UKC02
NOMESCO Finland
Cystoscopy
1.9
6.4
77
418
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
6.4
94
545
F61
ICD-10 Finland
Mixed and other personality disorders
14.5
6.4
10
7
IBA01, ,
SPAT
3.1
6.4
26
86
M01AH01
ATC
celecoxib; oral
1.9
6.4
88
500
N06AX17
ATC
milnacipran; oral
8.2
6.3
13
16
C08CA02
ATC
felodipine; oral
2.4
6.3
42
180
P80
ICPC
Personality disorder
11.1
6.3
11
10
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.8
6.3
31
115
A03FA02
ATC
cisapride; oral, rectal
2.3
6.2
44
194
K30
ICD-10 Finland
Functional dyspepsia
1.9
6.2
77
422
ZXY60
NOMESCO Finland
2-person team, nurses
7.1
6.2
14
20
F48.0
ICD-10 Finland
Neurasthenia
26.9
6.2
8
*
T90
ICPC
Diabetes non-insulin dependent
1.7
6.2
126
802
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
6.2
144
949
S01
ICPC
Pain/tenderness of skin
2.6
6.2
36
145
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.8
6.2
90
521
K07
ICPC
Swollen ankles/oedema
2.9
6.2
28
99
J01AA02
ATC
doxycycline; systemic
1.5
6.2
466
3944
P16
ICPC
Acute alcohol abuse
3.8
6.1
18
48
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.8
6.1
18
48
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
4.2
6.1
16
39
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
6.1
324
2559
AA40B, ,
NOMESCO Finland
12.6
6.1
10
8
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
3.2
6.1
23
73
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
6.1
54
263
ZXY56
NOMESCO Finland
2-person team, nurse-psychologist
10.1
6.0
11
11
Z72.8
ICD-10 Finland
Other problems related to lifestyle
10.1
6.0
11
11
IAB08
NOMESCO Finland
Consultation concerning a patient who has attempted suicide
10.1
6.0
11
11
J46
ICD-10 Finland
Status asthmaticus
3.5
6.0
20
58
E0000UV, ,
ATC
1.5
6.0
303
2365
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
6.0
557
4900

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
249
948
3.44
51.39
2.6
2.5
14.65
13.98
umol/l
0.77
237
884
232
877
3.38
48.02
2.6
2.5
2.40
2.38
g/l
0.19
218
808
310
1410
3.04
46.53
1.9
1.5
19.91
20.41
nmol/l
0.23
280
1206
212
796
3.32
43.92
2.7
2.6
23.76
23.51
%
0.11
203
748
416
2271
2.87
43.79
2.4
1.9
96.69
95.82
pmol/l
0.14
240
1214
462
2721
2.82
41.09
7.1
8.6
1.22
1.21
mmol/l
2.72
409
2383
355
1832
2.78
40.87
2.8
3.3
2.36
2.36
mmol/l
0.10
336
1702
100
232
4.82
40.86
2.3
2.5
—
—
—
0
0
425
2452
2.70
38.48
6.7
8.5
1.22
1.22
mmol/l
1.92
403
2281
619
4438
3.27
35.11
8.3
7.8
79.90
81.69
u/l
0.42
598
4221
443
2706
2.56
34.16
3.0
2.6
71.71
73.37
nmol/l
0.58
417
2498
173
715
2.85
29.09
2.0
1.6
1031.04
1122.84
nmol/l
0.67
138
537
108
343
3.51
28.41
1.7
1.7
0.21
0.28
mg/l
0.61
34
167
367
2186
2.33
28.09
3.8
3.5
27.78
32.47
u/l
1.85
351
2085
366
2180
2.33
27.98
6.7
7.1
—
—
—
0
0
385
2345
2.32
27.89
5.1
5.7
36.97
36.71
g/l
0.43
363
2213
637
4888
3.03
27.15
5.6
4.2
14.49
14.59
pmol/l
0.50
599
4510
486
3333
2.30
25.66
4.2
3.1
94.27
93.90
ug/l
0.02
458
3145
122
453
3.02
24.66
2.1
2.0
—
—
—
0
0
152
636
2.74
24.64
2.6
2.3
395.57
375.99
nmol/l
0.49
142
599
456
3083
2.22
24.41
7.0
7.1
0.67
0.67
%
0.01
434
2907
112
401
3.11
24.09
3.2
2.7
—
—
—
0
0
518
3700
2.30
24.05
9.8
9.9
4.08
3.95
e9/l
0.63
453
3212
462
3154
2.21
23.94
6.7
6.9
55.22
55.72
%
0.43
448
3030
455
3089
2.20
23.89
7.0
7.2
8.38
8.61
%
1.17
436
2919
480
3329
2.23
23.88
6.6
7.0
0.04
0.04
e9/l
0.04
422
2880
490
3433
2.24
23.68
6.8
7.3
0.19
0.19
e9/l
0.19
431
3028
478
3322
2.21
23.49
6.6
7.0
0.57
0.56
e9/l
0.21
422
2871
452
3087
2.17
23.02
6.9
7.0
2.69
2.88
%
0.99
432
2914
487
3425
2.21
23.01
6.7
7.0
2.11
2.02
e9/l
0.80
439
3047
278
1572
2.22
22.99
4.3
4.3
7.40
7.39
ph
0.42
194
1120
461
3201
2.14
22.12
6.9
7.0
30.33
29.72
%
0.63
449
3056
269
1554
2.14
20.63
2.9
2.2
2.60
2.75
mg/l
0.59
238
1337
127
530
2.68
20.45
2.1
2.0
—
—
—
0
0
131
562
2.61
19.93
2.1
2.0
—
—
—
0
0
130
559
2.60
19.67
1.9
2.0
—
—
—
0
0
192
985
2.28
19.67
1.9
1.7
38750435.41
25856392.05
pmol/l
0.12
160
847
131
570
2.57
19.33
2.2
2.0
—
—
—
0
0
433
3027
2.02
19.28
6.0
6.8
11.90
13.47
umol/l
0.94
404
2875
579
4511
2.25
19.17
4.6
3.3
43.74
40.70
u/l
0.49
561
4332
130
566
2.57
19.15
2.1
2.0
—
—
—
0
0
683
5787
3.05
17.87
7.3
4.9
1.80
1.86
mu/l
0.75
650
5432
268
1618
2.02
17.71
2.2
2.1
224.82
249.05
u/l
0.12
247
1547
673
5666
2.85
17.69
5.5
4.2
5.89
5.78
mmol/l
1.14
632
5260
275
1682
2.00
17.47
1.7
1.5
2.21
2.22
g/l
0.03
166
1046
189
1007
2.17
17.40
2.7
2.7
108.56
119.39
ug/g
0.14
158
810
177
935
2.17
16.56
1.5
1.4
611.85
513.75
titre
0.15
27
192
287
1814
1.94
16.34
3.1
2.6
75.51
62.75
u/l
0.24
267
1693
293
1871
1.93
16.13
1.6
1.4
1.51
1.64
u/ml
0.07
68
503
148
736
2.26
16.03
1.3
1.2
—
—
—
0
0
464
3466
1.89
15.44
5.8
5.9
6.54
6.48
mmol/l
0.24
438
3191
302
1976
1.89
15.22
3.6
3.6
8.21
8.31
mmol/l
0.11
254
1714
702
6154
3.24
14.98
20.0
14.6
139.63
139.61
mmol/l
0.13
693
6018
702
6162
3.22
14.78
20.1
14.7
3.93
3.95
mmol/l
1.11
693
6007
645
5448
2.32
14.59
6.6
5.3
38.88
38.15
mmol/mol
0.50
612
5170
123
588
2.31
14.54
2.7
2.5
24.61
31.95
u/l
4.38
95
499
98
425
2.50
14.39
2.5
2.4
9.23
15.69
au/ml
—
7
50
54
170
3.35
14.24
1.4
1.4
291.34
289.76
ug/g
0.02
32
96
168
927
2.05
13.77
2.5
2.7
2.41
2.43
mmol/l
1.44
154
838
166
930
2.01
12.97
3.4
4.8
0.83
0.82
mmol/l
0.43
148
893
530
4263
1.83
12.49
5.5
4.1
—
3.65
—
0
7
328
2322
1.73
11.92
5.4
3.8
28.79
77.87
e6/l
1.95
226
1565
95
443
2.31
11.82
4.9
4.1
7.37
7.34
ph
0.69
76
318
25
51
5.04
11.75
1.3
2.1
—
—
—
0
0
366
2697
1.70
11.29
3.7
3.2
6.11
6.23
ph
1.33
192
1524
501
4019
1.74
11.28
5.4
4.1
1865.10
1776.52
e6/l
—
10
56
703
6358
2.72
10.48
18.8
12.9
19.62
22.41
mg/l
1.64
588
5014
278
1933
1.70
10.43
4.3
3.2
12.74
97.58
e6/l
1.61
215
1466
140
793
1.94
10.42
6.2
7.9
1.11
1.11
mmol/l
0.05
130
743
723
6651
3.51
10.15
21.7
15.4
74.07
72.76
umol/l
0.40
717
6570
247
1677
1.71
10.05
4.1
3.1
0.24
0.31
e6/l
0.42
184
1214
80
375
2.27
9.80
1.7
1.7
345.18
296.63
mu/l
0.51
73
341
721
6646
3.27
9.60
14.3
10.4
28.91
27.24
u/l
1.09
710
6482
118
650
1.97
9.48
1.4
1.2
—
—
—
0
0
95
491
2.07
9.10
7.5
7.3
7.41
7.41
ph
0.04
77
406
196
1285
1.71
8.90
3.4
3.6
1088.94
992.23
ng/l
0.06
146
1060
105
568
1.99
8.87
2.1
3.1
10.41
10.38
g/l
0.02
95
523
42
152
2.87
8.79
2.0
3.1
7.86
2.21
index
0.57
20
92
181
1177
1.71
8.42
1.4
1.3
17.76
26.59
iu/ml
1.28
49
347
198
1319
1.68
8.42
3.3
2.6
6.49
6.80
e6/l
0.11
174
1182
178
1153
1.71
8.40
3.4
2.7
536.23
542.02
mosm/kgh2o
0.12
150
1002
221
1520
1.64
8.29
3.5
3.3
1.02
2.01
kg/l
0.50
140
1012
64
297
2.26
8.04
1.1
1.1
—
—
—
0
0
87
456
2.03
8.01
1.9
1.9
1.05
1.31
g/l
1.36
77
425
27
79
3.51
8.01
1.7
3.6
—
—
—
0
0
266
1928
1.59
7.99
4.5
3.2
30.24
37.17
ng/l
0.32
162
1155
81
414
2.07
7.99
4.9
3.8
4.57
4.79
pmol/l
1.23
68
374
44
172
2.66
7.98
1.5
2.1
411.43
471.92
mg/l
0.61
44
166
167
1078
1.71
7.93
1.3
1.3
14.09
8.46
u/ml
0.36
54
425
377
2964
1.55
7.87
12.1
10.8
0.00
0.00
e9/l
0.52
300
2401
419
3381
1.54
7.71
4.2
3.4
0.00
6.44
estimate
1.08
80
705
82
427
2.03
7.69
1.1
1.2
—
103.44
—
0
9
74
371
2.10
7.68
7.9
8.0
—
—
—
0
0
124
743
1.80
7.62
1.8
1.4
—
—
—
0
0
303
2288
1.54
7.49
10.9
10.3
1.20
1.17
inr
0.21
264
1898
419
3402
1.53
7.34
4.3
3.5
0.00
0.01
estimate
0.79
74
655
662
5997
1.89
7.33
5.7
4.8
2.72
2.75
mmol/l
0.49
627
5665
111
651
1.83
7.31
3.0
2.3
11.91
12.88
nmol/l
0.57
104
600
149
952
1.71
7.30
3.9
3.0
3.58
2.49
e6/l
0.41
73
460
110
644
1.83
7.28
1.4
1.4
—
—
—
0
0
262
1926
1.55
7.25
7.1
6.1
—
—
—
0
0
318
2439
1.53
7.25
2.0
1.9
1.49
1.34
mmol/l
2.04
270
2120
78
408
2.02
7.22
1.2
1.2
—
—
—
0
0
413
3354
1.52
7.15
4.2
3.4
0.00
0.00
estimate
-0.00
79
707
121
735
1.77
7.08
3.0
3.6
6.76
8.21
umol/l
0.46
100
644
40
159
2.60
7.04
1.4
2.4
11.55
10.34
e6/l
0.05
31
118
40
161
2.57
6.87
1.4
2.4
407.48
1273.17
e6/l
0.50
33
127
295
2250
1.51
6.79
2.3
2.0
—
—
—
0
0
203
1432
1.57
6.64
5.4
4.1
—
—
—
0
0
153
1010
1.65
6.58
3.7
2.9
1.01
0.89
e6/l
0.20
81
522
96
556
1.83
6.57
2.6
2.9
0.22
0.22
g/l
0.14
88
519
48
215
2.32
6.57
1.2
1.5
250.36
218.39
u/ml
0.39
27
117
91
521
1.85
6.46
7.8
9.8
6.83
7.83
mmol/l
0.82
84
503
65
333
2.04
6.38
8.5
8.4
24.37
24.27
mmol/l
0.10
60
322
191
1346
1.56
6.23
2.1
2.1
0.89
1.26
mg/l
1.52
141
1015
17
32
5.41
6.18
2.6
5.4
61.86
153.21
umol/l
—
7
19
211
1523
1.54
6.17
4.9
4.7
92.46
91.09
%
0.34
205
1495
16
28
5.81
6.17
1.8
2.0
15.39
18.33
umol/l
0.46
16
28
709
6646
2.25
6.10
16.5
11.1
—
—
—
0
0
35
143
2.52
5.86
1.5
2.5
—
—
—
0
0
197
1417
1.53
5.81
2.8
3.0
346.85
337.15
umol/l
0.67
172
1267
649
5934
1.70
5.77
5.1
4.3
1.45
1.43
mmol/l
0.06
612
5608
650
5953
1.70
5.65
5.2
4.4
4.54
4.63
mmol/l
1.43
619
5650
16
32
5.09
5.59
1.1
1.4
1.26
7.23
nmol/l
—
9
26
27
99
2.79
5.58
1.9
1.5
24.54
26.66
ng/l
0.19
27
99
23
78
3.01
5.45
1.4
1.2
—
—
—
0
0
22
73
3.07
5.41
1.7
3.2
—
—
—
0
0
101
634
1.69
5.23
2.7
3.7
1.76
1.71
%
0.17
87
569
121
809
1.59
4.87
2.1
2.1
—
—
—
0
0
199
1484
1.46
4.82
3.8
3.4
—
0.00
—
0
9
28
114
2.51
4.76
3.7
3.5
—
—
—
0
0
80
485
1.73
4.70
4.2
6.1
0.04
0.05
%
0.11
28
125
68
395
1.79
4.63
4.4
4.9
77.97
71.47
ng/l
0.22
60
363
35
701
0.47
4.61
1.9
1.6
3.47
3.45
mmol/l
0.03
24
472
215
1640
1.44
4.59
3.0
2.6
—
—
—
0
0
61
344
1.84
4.57
2.8
1.9
—
—
—
0
0
68
398
1.78
4.52
1.3
1.4
—
—
—
0
0
92
589
1.64
4.42
1.4
1.2
70.26
139.06
u/ml
1.80
24
220
204
1552
1.43
4.39
3.4
4.8
—
—
—
0
0
116
788
1.56
4.36
2.6
3.2
4.05
4.79
e9/l
0.75
94
699
75
458
1.71
4.30
2.1
3.5
70.02
67.77
e9/l
0.24
55
321
62
359
1.79
4.28
1.1
1.2
—
—
—
0
0
209
1605
1.42
4.26
4.7
4.3
9.91
9.39
mg/mmol
0.06
135
1033
45
235
1.97
4.25
1.6
1.6
2.08
6.49
u/ml
—
5
52
41
207
2.04
4.25
1.1
1.1
1.23
10.33
eliau/ml
—
9
28
206
1581
1.42
4.20
4.0
3.6
44.72
56.81
mg/l
0.55
140
1052
610
5601
1.48
4.18
4.5
3.8
1.40
1.25
mmol/l
3.15
568
5275
29
128
2.32
4.18
1.4
1.7
0.63
0.79
g/l
0.46
20
102
19
68
2.84
4.14
1.5
1.3
—
—
—
0
0
41
209
2.02
4.14
1.2
1.3
66.00
75.86
titre
—
5
29
19
69
2.80
4.04
1.5
1.3
2.79
2.68
g/l
0.09
14
49
7
7
10.08
4.01
1.4
1.1
—
—
—
0
0
20
76
2.68
3.92
1.4
1.4
287.20
472.99
pmol/l
0.66
15
68
86
566
1.59
3.71
5.8
12.0
—
—
—
0
0
733
7100
2.52
3.52
28.7
19.5
262.14
255.52
e9/l
1.99
719
6978
11
26
4.28
3.51
2.2
2.7
40.09
29.58
%
0.72
11
26
42
230
1.88
3.49
1.2
1.2
—
—
—
0
0
18
69
2.65
3.49
1.5
1.3
0.36
0.35
g/l
0.04
13
47
18
69
2.65
3.49
1.5
1.3
7.22
6.54
g/l
0.48
13
49
733
7105
2.48
3.42
28.5
19.4
90.04
89.77
fl
0.89
727
7051
24
107
2.28
3.42
4.5
2.6
1.89
2.28
mmol/l
0.26
18
59
62
384
1.67
3.41
5.8
4.1
1.23
1.23
mmol/l
0.06
50
343
733
7107
2.47
3.38
28.5
19.4
30.11
30.04
pg
0.56
727
7052
733
7107
2.47
3.38
28.9
20.1
40.92
41.37
%
0.30
726
7048
733
7107
2.47
3.38
28.6
19.5
4.58
4.58
e12/l
0.03
721
6970
13
42
3.13
3.38
2.8
3.0
0.62
0.79
index
0.47
13
42
245
1994
1.34
3.38
2.5
2.3
—
—
—
0
0
8
14
5.76
3.34
2.5
1.9
—
—
—
0
0
55
332
1.71
3.33
1.6
1.7
7.20
7.75
u/l
0.14
40
271
733
7110
2.45
3.32
28.7
19.5
6.97
6.75
e9/l
2.08
719
6969
733
7113
2.43
3.26
28.8
19.7
137.16
136.84
g/l
0.23
727
7056
92
638
1.50
3.16
4.8
6.5
7.38
7.37
ph
0.27
52
386
72
474
1.57
3.12
3.6
5.3
0.65
0.51
%
0.21
23
139
132
984
1.41
3.12
3.5
3.4
91.44
768.91
ng/l
3.19
84
658
75
499
1.56
3.11
3.9
5.7
0.65
0.93
%
0.51
26
153
54
331
1.68
3.11
1.1
1.1
—
—
—
0
0
14
50
2.83
3.10
2.0
1.2
117.14
107.16
pmol/l
0.33
14
50
224
1819
1.33
3.10
4.1
3.5
0.00
0.01
estimate
0.69
74
671
16
62
2.62
3.06
1.3
2.1
0.94
0.93
%
0.01
11
36
72
477
1.56
3.04
4.0
5.8
0.00
0.11
%
3.05
22
131
89
619
1.50
3.02
4.8
6.5
2.03
1.39
mmol/l
1.12
76
517
16
63
2.57
2.97
1.3
2.4
32.94
32.37
pg
0.15
16
63
106
766
1.45
2.96
1.9
1.6
—
—
—
0
0
25
121
2.10
2.95
1.2
1.1
2.57
2.97
eliau/ml
0.12
13
43
9
22
4.13
2.89
1.1
1.4
133.89
141.64
nmol/l
—
9
22
16
64
2.53
2.89
2.4
4.7
—
—
—
0
0
16
64
2.53
2.89
1.4
1.4
8.67
9.74
u/ml
0.05
11
40
68
453
1.55
2.82
1.5
1.4
—
—
—
0
0
47
286
1.69
2.80
1.6
1.8
4.49
6.05
iu/ml
—
8
64
48
294
1.68
2.79
1.5
3.0
—
—
—
0
0
79
550
1.49
2.68
4.4
11.6
1.65
0.61
mmol/l
1.76
69
465
9
25
3.63
2.58
1.0
1.7
5.93
4.57
nmol/l
—
9
25
8
20
4.03
2.57
1.1
1.3
111.46
65.10
nmol/24h
—
8
20
101
747
1.41
2.50
1.8
1.9
—
—
—
0
0
78
551
1.46
2.47
4.6
11.6
7.41
7.42
ph
0.11
47
292
595
5589
1.31
2.38
22.4
16.4
13.40
13.39
%
0.13
589
5521
12
46
2.63
2.37
1.1
1.0
—
—
—
0
0
99
738
1.39
2.35
3.8
9.4
104.02
104.48
mmol/l
0.43
99
738
184
1510
1.29
2.29
2.4
2.3
—
—
—
0
0
24
127
1.92
2.28
1.1
1.1
376.80
93.32
iu/ml
—
5
34
240
2041
1.26
2.23
2.7
2.1
—
—
—
0
0
5
9
5.58
2.21
1.0
1.3
—
—
—
0
0
136
1076
1.32
2.21
1.9
1.6
—
—
—
0
0
60
412
1.50
2.21
1.4
1.6
20.29
20.66
iu/l
0.03
42
349
40
250
1.63
2.20
2.7
6.5
—
—
—
0
0
14
61
2.32
2.15
2.4
1.5
0.56
0.49
e9/l
0.49
14
61
6
14
4.31
2.15
1.7
2.0
2.33
1.74
nmol/l
—
6
14
292
2550
1.24
2.12
3.9
3.2
0.00
0.00
estimate
0.80
65
582
34
206
1.68
2.11
1.4
1.3
—
—
—
0
0
23
124
1.88
2.09
1.7
1.8
—
—
—
0
0
36
223
1.65
2.06
1.5
1.3
—
—
—
0
0
32
192
1.70
2.06
1.4
1.6
—
—
—
0
0
38
241
1.61
1.99
2.2
2.1
—
—
—
0
0
13
57
2.30
1.98
2.2
2.7
—
—
—
0
0
16
77
2.10
1.97
1.7
1.4
285.20
285.26
mosm/kgh2o
—
10
57
36
226
1.62
1.97
1.3
1.1
—
—
—
0
0
14
64
2.21
1.95
1.6
3.2
3.59
86.44
nmol/l
0.49
14
64
224
1922
1.24
1.88
3.9
2.9
0.00
0.01
estimate
1.08
66
559
36
229
1.60
1.88
4.1
5.9
235.33
385.52
mg/l
1.01
18
119
18
327
0.54
1.86
1.2
1.1
1.53
1.49
g/l
0.17
18
327
26
152
1.74
1.85
2.7
1.5
0.22
0.36
nmol/l
1.64
21
122
55
386
1.46
1.85
3.3
3.2
—
—
—
0
0
19
339
0.55
1.85
1.5
1.1
0.85
0.90
g/l
0.35
19
339
14
66
2.14
1.83
1.4
1.3
—
—
nmol/l
—
0
0
185
1564
1.24
1.77
4.3
4.6
2.02
2.05
ug/l
0.02
167
1423
27
162
1.69
1.77
1.1
1.1
4.83
6.63
u/ml
0.26
14
90
26
155
1.70
1.74
2.7
2.9
50.96
55.96
%
1.08
26
155
39
258
1.54
1.74
1.3
1.3
—
—
—
0
0
74
556
1.37
1.71
2.0
2.0
0.00
0.02
estimate
0.50
17
149
5
13
3.86
1.71
1.4
7.5
20.84
24.94
mmol/l
—
5
13
11
48
2.31
1.71
1.4
1.4
4.23
6.04
ug/l
1.33
11
40
17
89
1.93
1.71
1.4
1.4
65.67
68.47
mmol/l
0.07
12
74
325
2921
1.20
1.68
2.8
2.8
—
—
estimate
—
0
0
68
507
1.38
1.66
2.1
2.4
803.50
4107.14
u/l
2.21
16
208
14
69
2.05
1.65
1.1
1.2
—
—
—
0
0
26
159
1.66
1.61
1.1
1.1
2.01
0.49
u/ml
—
8
66
19
106
1.81
1.60
2.3
3.3
4.13
3.95
e9/l
0.13
19
106
93
732
1.31
1.59
1.3
1.2
—
—
—
0
0
233
2639
0.83
1.58
3.1
2.7
—
—
—
0
0
29
184
1.60
1.56
1.3
1.2
—
—
—
0
0
10
44
2.29
1.56
1.0
1.1
—
—
—
0
0
13
64
2.05
1.55
1.2
1.2
—
—
—
0
0
44
309
1.45
1.51
2.5
3.2
86.07
152.06
ng/l
1.68
38
277
89
705
1.30
1.47
1.4
1.4
—
—
—
0
0
67
516
1.33
1.36
4.2
3.3
—
—
—
0
0
5
17
2.95
1.36
1.0
1.3
—
—
—
0
0
21
129
1.65
1.31
1.7
1.4
17.93
18.20
u/l
0.01
16
109
22
137
1.62
1.30
2.2
1.4
339.82
354.05
mu/l
0.09
17
110
5
18
2.79
1.28
2.6
1.8
—
—
—
0
0
27
178
1.54
1.28
1.4
1.6
114.80
134.21
au/ml
—
5
60
62
793
0.76
1.25
1.2
1.3
—
—
—
0
0
9
45
2.01
1.23
1.1
1.1
—
—
—
0
0
24
157
1.55
1.18
3.2
2.7
—
—
—
0
0
16
94
1.72
1.18
4.0
3.9
9.49
7.89
pmol/l
0.19
16
94
0
33
0.00
1.16
0.0
1.7
—
4533.33
—
0
6
5
20
2.51
1.15
1.4
1.8
0.78
3.23
u/ml
—
5
14
42
311
1.37
1.13
2.4
2.1
0.00
0.01
estimate
0.50
13
121
8
40
2.01
1.12
2.4
2.4
385.00
767.95
u/ml
—
8
40
37
269
1.39
1.11
4.1
8.6
24.84
24.37
mmol/l
0.50
37
254
5
21
2.39
1.09
5.4
3.4
0.63
0.60
mmol/l
—
5
21
5
21
2.39
1.09
6.2
2.0
—
—
—
0
0
7
32
2.20
1.08
1.0
1.2
—
86.50
%
—
0
6
38
280
1.38
1.06
12.8
9.7
8.87
9.06
kpa
0.24
38
274
87
719
1.24
1.06
1.7
1.5
—
—
—
0
0
110
932
1.21
1.05
2.6
2.8
0.61
0.73
ug/l
1.29
65
538
38
281
1.37
1.04
2.4
6.5
0.53
0.61
%
1.18
38
281
5
22
2.28
1.03
2.2
2.5
1.50
4.49
ug/l
—
5
22
19
122
1.57
1.03
1.6
1.2
—
—
—
0
0
9
49
1.85
0.99
2.3
1.2
—
—
—
0
0
62
499
1.26
0.96
3.3
2.0
6.06
6.22
ph
0.80
43
315
11
62
1.79
0.94
2.1
2.4
—
—
—
0
0
26
184
1.43
0.92
1.1
1.1
3.44
6.17
u/ml
0.39
13
109
62
504
1.25
0.89
4.5
12.3
94.84
96.03
%
0.55
62
489
6
29
2.08
0.89
2.7
2.4
532.33
512.39
min
—
6
18
6
31
1.94
0.84
2.0
3.5
—
—
—
0
0
10
57
1.76
0.84
1.6
1.3
1.15
1.55
nmol/l
—
10
48
30
224
1.35
0.81
2.0
2.0
1.58
1.37
g/l
0.56
25
194
8
47
1.71
0.81
1.0
1.1
—
—
—
0
0
10
58
1.73
0.80
1.1
1.3
148.35
174.34
pmol/l
—
10
58
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
8
48
1.67
0.79
1.0
1.1
—
—
—
0
0
22
303
0.72
0.78
1.3
1.5
—
—
—
0
0
13
82
1.60
0.78
3.0
2.3
—
—
—
0
0
10
59
1.70
0.76
2.5
1.4
2.19
1.34
promille
—
5
49
9
53
1.71
0.75
1.2
1.1
—
—
—
0
0
24
175
1.38
0.75
7.4
9.1
—
—
—
0
0
13
83
1.58
0.75
1.2
1.4
1.05
3.04
u/ml
—
6
41
7
38
1.85
0.73
3.0
3.3
819.86
890.18
mg
—
7
38
7
38
1.85
0.73
1.4
1.7
0.15
2.96
u/ml
—
7
38
9
55
1.64
0.73
2.0
2.0
—
—
—
0
0
5
25
2.01
0.72
6.2
1.9
—
—
—
0
0
7
39
1.80
0.72
1.6
5.2
—
117.51
—
0
15
30
229
1.32
0.72
1.1
1.1
7.43
4.79
u/ml
0.31
16
151
19
135
1.42
0.69
1.2
1.1
—
—
—
0
0
7
42
1.67
0.68
2.3
1.4
74.43
75.21
umol/l
—
7
42
23
306
0.74
0.68
1.4
1.6
—
—
—
0
0
5
28
1.79
0.66
1.4
4.7
6.48
8.63
mmol/l
—
5
28
5
28
1.79
0.66
1.2
1.5
—
—
—
0
0
11
71
1.56
0.62
1.7
1.3
—
—
—
0
0
5
30
1.67
0.61
5.8
8.0
61.20
471.01
ug/l
—
5
24
5
30
1.67
0.61
1.2
1.3
—
—
—
0
0
8
51
1.57
0.60
1.6
1.7
—
—
—
0
0
12
80
1.51
0.60
1.3
1.4
0.44
3.19
u/ml
—
5
47
6
36
1.67
0.56
1.3
1.8
1.06
1.38
nmol/l
—
6
27
6
37
1.63
0.55
2.7
2.4
571.83
541.25
ml
—
6
20
12
83
1.45
0.52
1.6
2.3
—
—
—
0
0
55
474
1.17
0.50
4.6
11.7
126.67
121.36
g/l
1.01
55
463
28
225
1.25
0.50
1.1
1.1
4.19
1.60
u/ml
—
10
121
17
127
1.35
0.50
2.4
2.7
136.08
128.54
g/l
0.43
12
103
10
67
1.50
0.50
2.8
15.4
12.17
11.74
%
—
10
67
14
102
1.38
0.47
1.1
1.1
—
—
—
0
0
12
85
1.42
0.47
1.2
1.8
—
—
—
0
0
7
48
1.46
0.47
5.6
3.4
0.81
0.88
nmol/l
—
7
39
31
255
1.22
0.46
1.1
1.2
3.73
3.01
u/ml
0.09
14
160
111
1214
0.90
0.46
1.6
1.6
—
—
—
0
0
27
219
1.24
0.45
1.1
1.2
1.61
2.36
u/ml
0.27
15
133
5
32
1.57
0.42
1.8
2.2
—
—
—
0
0
5
32
1.57
0.42
3.2
3.1
2.64
2.57
mmol/l
—
5
24
40
343
1.18
0.40
1.3
1.4
234.03
248.90
miu/ml
0.08
16
172
0
17
0.00
0.40
0.0
4.2
—
6.23
—
0
17
0
18
0.00
0.40
0.0
7.4
—
4.82
—
0
18
13
97
1.35
0.39
1.3
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
156
1664
0.92
0.39
1.9
1.8
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
133.42
186.33
iu/ml
—
5
36
11
81
1.36
0.36
1.4
1.4
—
—
—
0
0
15
118
1.28
0.33
1.5
1.3
12.43
3.18
u/ml
—
7
51
6
88
0.68
0.33
1.0
1.1
—
—
—
0
0
6
46
1.31
0.33
1.3
2.9
—
—
—
0
0
30
257
1.17
0.32
2.5
1.8
—
—
—
0
0
42
373
1.13
0.29
2.7
2.3
2.55
7.88
ug/l
6.08
32
336
18
148
1.22
0.29
1.6
4.6
57.99
78.96
mg/l
0.20
12
126
18
148
1.22
0.29
1.6
4.6
30.17
41.90
mg/l
0.38
12
127
585
5769
1.06
0.27
22.8
16.1
333.98
333.79
g/l
0.20
580
5736
22
187
1.18
0.27
1.2
1.1
—
—
—
0
0
126
1332
0.94
0.26
2.2
1.9
—
—
—
0
0
13
104
1.25
0.26
1.4
1.2
—
—
—
0
0
5
72
0.69
0.26
3.8
3.7
27.46
28.64
u/ml
—
5
72
15
123
1.22
0.25
3.5
4.5
91.63
90.84
%
0.29
15
118
16
133
1.21
0.24
1.6
4.5
1.19
2.26
ratio
—
6
76
10
125
0.80
0.23
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
12.74
—
0
5
0
12
0.00
0.21
0.0
2.2
—
6103.17
—
0
12
8
103
0.77
0.21
1.3
1.6
—
—
—
0
0
8
103
0.77
0.21
1.3
1.6
—
—
—
0
0
8
103
0.77
0.21
1.3
1.6
—
—
—
0
0
8
103
0.77
0.21
1.3
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
37.91
—
0
7
11
134
0.82
0.20
1.0
1.1
—
—
—
0
0
6
48
1.25
0.20
2.2
3.0
—
—
—
0
0
32
289
1.11
0.19
5.2
15.8
16.88
15.80
%
1.15
32
276
21
186
1.13
0.17
1.2
1.1
—
—
—
0
0
6
80
0.75
0.15
1.0
1.0
11.35
8.36
mu/l
—
6
74
47
442
1.07
0.13
2.4
4.9
3.53
17.91
ug/l
0.82
41
352
9
109
0.82
0.13
1.1
1.5
—
—
—
0
0
10
85
1.18
0.12
2.2
1.3
—
47.05
—
0
6
10
116
0.86
0.12
3.1
4.0
—
—
—
0
0
217
2208
0.98
0.09
1.5
1.7
—
—
—
0
0
19
207
0.92
0.09
1.8
2.2
1.43
5.27
iu/l
—
5
88
6
57
1.05
0.08
1.3
1.1
—
—
—
0
0
6
58
1.03
0.08
1.3
1.1
—
—
—
0
0
5
62
0.81
0.08
2.2
2.0
—
—
—
0
0
8
75
1.07
0.07
1.6
1.2
—
—
—
0
0
36
345
1.05
0.06
1.7
1.6
—
—
—
0
0
10
90
1.11
0.05
2.5
11.3
11.40
11.11
mmol/l
—
10
79
10
91
1.10
0.04
2.5
11.2
106.30
105.26
mmol/l
—
10
80
10
109
0.92
0.04
1.2
1.3
—
—
—
0
0
13
126
1.03
0.00
1.0
1.1
—
—
—
0
0
14
144
0.97
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
3.4
—
102.00
—
0
9
0
5
0.00
0.00
0.0
1.4
—
34.60
—
0
5
0
6
0.00
0.00
0.0
15.8
—
110.00
—
0
6
0
6
0.00
0.00
0.0
1.0
—
0.34
—
0
6
0
9
0.00
0.00
0.0
6.1
—
7.37
—
0
9
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
61
0.98
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
16.58
—
0
5
0
5
0.00
0.00
0.0
5.0
—
4.36
—
0
5
7
72
0.97
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
248.57
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.5
—
0.24
—
0
8
8
79
1.01
-0.00
1.4
1.6
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
80.00
—
0
8

Mortality – FinRegistry

↥

Association

Association between endpoint F5_SLEEPWAKE and mortality.

Females

Parameter HR [95% CI] p-value
F5_SLEEPWAKE 2.192 [1.67, 2.88] < 0.001
Birth year 0.99 [0.98, 1.0] 0.03

During the follow-up period (1.1.1998 — 31.12.2019), 157 out of 2225 females with F5_SLEEPWAKE died.

Males

Parameter HR [95% CI] p-value
F5_SLEEPWAKE 2.046 [1.64, 2.55] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 288 out of 2839 males with F5_SLEEPWAKE died.

Mortality risk

Mortality risk for people of age

years, who have F5_SLEEPWAKE.

N-year risk Females Males
1 0.236% 0.3%
5 1.1% 2.454%
10 2.53% 6.216%
15 4.99% 11.799%
20 8.937% 19.409%

Relationships between endpoints

↥

Index endpoint: F5_SLEEPWAKE – Disorder of the sleep-wake schedule

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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