No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
152 |
4. Check minimum number of eventsNone |
152 |
5. Include endpointsNone |
152 |
6. Filter based on genotype QC (FinnGen only) |
129 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF13
- Parent code in ICD-10
- Q6[5-9]|Q7
- Name in latin
- Syndactylia
Similar endpoints
↥List of similar endpoints to
Syndactyly, including avohilmo
based on the number of shared cases.
Similar with more cases:
- Congenital malformations and deformations of the musculoskeletal system, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 129 | 85 | 44 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | 34.32 | 28.34 | 45.88 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 135
- Matched controls
- 1350
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q70.1
ICD-10 Finland
Webbed fingers
+∞
62.4
55
*
Q70.9
ICD-10 Finland
Syndactyly, unspecified
+∞
46.6
42
*
Q70.3
ICD-10 Finland
Webbed toes
+∞
24.7
23
*
Q70.0
ICD-10 Finland
Fused fingers
+∞
14.9
14
*
NDT38
NOMESCO Finland
Correction of joined fingers
+∞
13.8
13
*
7551A
ICD-9 Finland
Other congenital anomalies of limbs, Syndactyly[SYNDACTYLIA]
+∞
9.5
9
*
9493
FHL
Reconstruction or shaping of hand skin and soft tissues, e.g. syndactyl
+∞
8.4
8
*
AA1AD
NOMESCO Finland
CT of head and brain
3.2
8.4
43
172
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
7.0
29
101
R55
ICD-10 Finland
Syncope and collapse
3.9
6.9
22
64
G70.0
ICD-10 Finland
Myasthenia gravis
+∞
6.3
6
*
108
Kela drug reimbursment
Myasthenia gravis
+∞
6.3
6
*
75512
ICD-8 Finland
Other congenital anomalies of limbs, Syndactylia cum reductione phalangis, manus
+∞
6.3
6
*
N07AA02
ATC
pyridostigmine; systemic
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
11
19
6.20
4.55
4.1
2.9
1.55
1.23
mmol/l
0.68
11
19
58
384
1.89
3.20
1.9
1.9
—
—
—
0
0
6
8
7.78
3.08
1.0
1.9
3.00
1.97
mmol/l
—
6
8
33
183
2.06
3.00
5.1
2.7
48.84
251.17
ng/l
1.46
19
114
13
47
2.95
2.91
5.5
3.0
0.57
0.59
%
0.09
13
47
12
39
3.28
2.85
3.3
2.9
26.12
24.49
mmol/l
0.75
12
39
48
310
1.85
2.80
4.0
3.2
16.35
45.93
ng/l
0.92
33
181
82
624
1.80
2.76
11.4
4.7
6.50
6.34
mmol/l
0.31
76
578
12
42
3.04
2.62
5.5
3.5
52.82
49.02
%
0.21
12
42
6
11
5.65
2.57
2.0
3.3
109.00
105.64
mmol/l
—
6
11
6
11
5.65
2.57
2.0
3.3
1.25
1.18
mmol/l
—
6
11
66
481
1.73
2.50
8.7
6.9
1.22
1.21
mmol/l
0.19
59
430
19
93
2.21
2.35
7.4
3.5
4.34
5.03
kpa
1.70
19
93
42
273
1.78
2.35
4.8
3.4
1.01
1.02
kg/l
0.71
32
178
23
125
2.01
2.19
11.1
7.7
105.87
105.09
mmol/l
0.33
23
125
35
220
1.80
2.17
3.7
2.1
1.04
1.04
mg/l
0.01
27
163
6
15
4.13
2.06
1.2
1.0
1.32
1.28
g/l
—
6
15
17
86
2.12
1.95
4.9
2.9
0.09
0.15
e6/l
0.36
17
79
14
67
2.22
1.83
1.7
1.4
—
—
—
0
0
33
214
1.72
1.83
7.3
3.4
855.85
729.50
ng/l
0.17
27
173
25
151
1.80
1.75
1.6
1.8
—
—
—
0
0
19
105
1.94
1.74
1.5
1.6
—
—
—
0
0
5
13
3.95
1.73
1.0
1.2
—
—
—
0
0
10
40
2.62
1.70
1.5
1.4
—
—
—
0
0
19
106
1.92
1.69
1.6
1.5
—
—
—
0
0
40
279
1.62
1.68
3.2
2.3
82.15
404.67
u/l
0.83
40
273
76
615
1.54
1.66
4.7
3.7
0.00
0.00
estimate
-0.00
11
126
5
14
3.67
1.63
1.0
1.2
—
—
—
0
0
42
301
1.57
1.57
2.8
3.0
0.17
0.25
e6/l
0.29
28
218
7
27
2.68
1.53
1.9
2.2
—
—
—
0
0
68
545
1.50
1.51
2.9
2.7
—
—
estimate
—
0
0
74
608
1.48
1.43
4.7
3.6
0.00
0.00
estimate
-0.00
11
132
7
29
2.49
1.41
1.1
1.2
—
—
—
0
0
58
455
1.48
1.41
4.9
3.4
0.00
0.01
estimate
—
9
105
5
17
3.01
1.37
1.0
1.6
—
—
—
0
0
10
48
2.17
1.31
1.4
1.7
—
—
—
0
0
74
615
1.45
1.31
4.7
3.6
0.00
0.00
estimate
-0.00
11
131
59
478
1.42
1.16
2.9
2.4
69.08
73.57
nmol/l
0.72
52
434
25
173
1.55
1.07
2.4
2.9
1.36
4.31
e6/l
2.16
11
94
122
1140
1.73
1.06
18.7
12.5
21.73
21.22
mg/l
0.07
108
907
7
36
1.99
0.98
3.9
2.4
22.36
23.72
mmol/l
—
7
36
6
29
2.12
0.90
1.0
1.1
—
—
—
0
0
25
181
1.47
0.88
2.3
2.7
1.29
0.92
e6/l
—
10
101
104
953
1.40
0.85
5.9
5.1
38.04
37.75
mmol/mol
0.13
97
910
24
319
0.70
0.82
2.6
2.4
—
—
—
0
0
12
74
1.68
0.81
8.2
4.2
24.29
24.01
mmol/l
0.19
12
74
12
74
1.68
0.81
5.9
3.9
76.60
74.27
ng/l
0.03
12
67
22
159
1.46
0.79
10.0
3.1
0.82
0.81
mmol/l
0.08
22
151
50
416
1.32
0.78
2.1
1.9
101.30
93.43
pmol/l
0.56
30
222
6
106
0.55
0.76
3.0
4.1
32.83
32.57
%
—
6
67
73
642
1.30
0.76
3.4
3.1
77.45
73.22
ug/l
0.12
68
610
5
25
2.04
0.73
2.0
1.4
—
—
—
0
0
13
85
1.59
0.72
1.2
1.8
—
—
—
0
0
5
26
1.96
0.71
1.0
1.3
—
1.20
—
0
10
10
62
1.66
0.67
2.0
1.7
—
—
—
0
0
39
322
1.30
0.63
4.4
3.6
0.00
0.01
estimate
0.50
11
127
8
49
1.67
0.63
1.9
1.6
—
—
—
0
0
8
50
1.64
0.62
2.6
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
0
20
0.00
0.61
0.0
1.6
—
—
—
0
0
0
23
0.00
0.59
0.0
3.2
—
0.00
—
0
23
18
133
1.41
0.59
2.6
2.6
23.56
24.71
%
0.17
18
128
42
354
1.27
0.58
4.7
3.2
0.13
0.00
estimate
—
8
108
9
61
1.51
0.55
4.0
4.6
1.24
1.22
mmol/l
—
9
55
7
47
1.52
0.48
73.4
13.9
24.14
24.39
mmol/l
—
7
47
111
1056
1.29
0.48
5.6
5.2
1.76
1.82
mu/l
0.24
106
996
106
1004
1.26
0.47
14.8
11.5
89.93
92.89
ml/min/173m2
0.62
91
883
24
291
0.79
0.44
2.7
2.2
—
—
—
0
0
12
87
1.42
0.44
51.2
9.1
24.42
24.68
mmol/l
0.15
12
87
111
1060
1.27
0.43
4.6
4.6
2.71
2.72
mmol/l
0.06
104
1003
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
31
264
1.23
0.39
3.3
4.1
17.94
13.55
mg/mmol
0.10
17
163
10
73
1.40
0.35
3.2
3.6
4.52
4.80
pmol/l
—
10
66
6
45
1.35
0.34
4.3
1.8
42.67
40.13
u/l
—
6
38
7
53
1.34
0.31
73.4
13.3
0.50
0.63
%
—
7
53
7
56
1.26
0.30
73.4
12.7
0.94
1.12
%
—
7
56
12
94
1.30
0.29
44.3
9.0
0.44
1.05
mmol/l
0.30
12
78
5
73
0.67
0.27
1.0
1.3
419.01
301.66
miu/ml
—
5
37
5
75
0.65
0.26
1.2
4.3
1.92
10.35
ug/l
—
5
59
24
210
1.17
0.24
1.8
2.2
—
—
—
0
0
7
95
0.72
0.23
1.1
1.1
—
—
—
0
0
21
182
1.18
0.23
3.7
2.4
2.43
2.43
mmol/l
0.01
15
157
108
1048
1.15
0.22
4.2
4.1
1.43
1.45
mmol/l
0.19
103
989
5
42
1.20
0.21
1.2
1.1
—
—
—
0
0
5
42
1.20
0.21
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
4.7
—
157.45
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.0
1.0
1.69
1.51
g/l
—
6
49
6
49
1.23
0.20
1.0
1.0
0.95
0.85
g/l
—
6
49
93
901
1.10
0.17
4.2
4.3
14.05
14.52
pmol/l
1.20
84
834
24
218
1.12
0.15
1.5
1.3
9.50
26.04
iu/ml
—
7
69
5
45
1.12
0.10
1.2
1.7
30.00
35.89
nmol/l
—
5
45
8
74
1.09
0.07
1.4
1.8
—
—
—
0
0
40
384
1.06
0.07
1.4
1.5
0.78
2.02
u/ml
—
8
87
9
87
1.04
0.07
1.6
1.4
—
—
—
0
0
14
128
1.10
0.07
2.6
2.4
1674.42
6077.39
u/l
—
6
51
9
88
1.02
0.07
1.8
3.1
—
—
—
0
0
19
180
1.06
0.04
1.7
2.0
—
—
—
0
0
97
959
1.04
0.04
4.5
3.9
—
—
—
0
0
15
159
0.94
0.03
1.1
1.9
2.96
3.39
ratio
—
8
125
10
94
1.07
0.01
5.9
2.2
13.14
13.19
nmol/l
—
10
89
27
264
1.03
0.00
2.6
2.1
—
—
—
0
0
11
114
0.96
0.00
1.5
1.5
—
—
—
0
0
17
174
0.97
0.00
4.0
4.2
16.60
22.42
%
—
5
73
25
251
1.00
0.00
1.6
1.5
—
—
—
0
0
20
197
1.02
0.00
1.5
1.3
2.74
9.66
u/ml
—
7
80
42
416
1.01
0.00
2.0
1.9
1.39
1.37
mmol/l
0.04
33
363
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
11.10
—
0
7
9
93
0.97
-0.00
1.1
1.3
—
—
—
0
0
5
59
0.84
-0.00
8.2
5.3
24.30
24.41
mmol/l
—
5
59
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
70.14
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
10.86
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.6
—
25.50
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
198.60
—
0
5
0
7
0.00
-0.00
0.0
5.0
—
4.63
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
12.92
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.33
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
1227.71
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
69
0.86
-0.00
1.5
1.6
70.57
54.10
ug/l
—
6
69
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
333.80
—
0
5
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_SYNDACTYLY_WIDE – Syndactyly, including avohilmo
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).