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Maternal care for (suspected) damage to fetus from alcohol

MESH Endpoint Browser PheWeb

MATERNCAREFETUSALCO

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O35.4
  • Cause of death: ICD-10 — O35.4

2 out of 7 registries used, show all original rules.

131

4. Check minimum number of events

None

131

5. Include endpoints

None

131

6. Filter based on genotype QC (FinnGen only)

114

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
O35
Name in latin
Cura matris propter laesionem [suspectam] fetus ex abusu alcohol matris

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 998 989 -
Only index persons 962 962 -
Unadjusted period prevalence (%)
Whole population 0.03 0.03 -
Only index persons 0.04 0.04 -
Median age at first event (years)
Whole population - 29.01 -
Only index persons - 28.94 -

-FinnGen-

Key figures

All Female Male
Number of individuals 114 114 -
Unadjusted period prevalence (%) 0.04 0.04 -
Median age at first event (years) 30.15 30.15 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
123
Matched controls
1230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O35.4
ICD-10 Finland
Maternal care for (suspected) damage to fetus from alcohol
+∞
177.6
123
*
Z2446
NOMESCO Finland
Social worker
33.8
85.4
67
42
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
28.4
63.6
49
28
N07BB01
ATC
disulfiram; oral
33.7
58.8
41
18
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
619.5
45.3
42
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
15.8
34.9
34
29
Z2221
NOMESCO Finland
Medical doctor
9.1
30.2
92
303
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
9.2
28.2
43
68
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
11.0
28.0
35
43
B18.2
ICD-10 Finland
Chronic viral hepatitis C
65.3
26.7
30
6
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
6.9
25.9
64
167
P15
ICPC
Chronic alcohol abuse
44.7
23.3
28
8
F32.9
ICD-10 Finland
Depressive episode, unspecified
6.4
23.0
56
142
RS120, ,
NOMESCO Finland
+∞
21.5
20
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
59.0
21.0
24
5
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
6.7
20.7
94
402
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
125.4
20.3
21
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
5.6
20.1
60
179
Z3231
NOMESCO Finland
Registered nurse
5.5
19.9
64
203
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
9.4
19.5
26
34
N05AH04
ATC
quetiapine; oral
5.1
18.3
64
215
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
23.1
18.3
26
14
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
9.0
18.1
25
34
N05BA04
ATC
oxazepam; oral
5.0
18.0
71
262
N05BA01
ATC
diazepam; systemic, rectal
6.1
16.6
35
75
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
13.6
16.0
28
26
N05AH03
ATC
olanzapine; systemic
6.5
15.8
30
58
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
7.8
15.6
24
37
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
7.2
15.5
26
44
N05BA12
ATC
alprazolam; oral
6.3
15.2
30
60
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
4.4
15.0
64
243
XF400
NOMESCO Finland
ECG with 12 standard connections
6.3
15.0
29
57
ZY010
NOMESCO Finland
Hospital outpatient
6.4
14.7
28
54
N06AX11
ATC
mirtazapine; oral
4.4
14.6
76
332
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
7.9
14.6
22
33
N06AB04
ATC
citalopram; systemic
4.5
14.2
48
152
D10
ICPC
Vomiting
5.7
14.0
31
69
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
7.4
13.8
22
35
A97
ICPC
No disease
4.3
13.6
52
180
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
7.2
13.4
22
36
MAX99
NOMESCO Finland
Assistance to normal delivery
4.1
13.4
58
219
LCH11
NOMESCO Finland
Pharmacologic abortion
5.1
13.2
34
86
Z37.0
ICD-10 Finland
Single live birth
4.1
13.1
58
222
EB1AA, ,
SPAT
6.1
13.1
26
52
F10.24
ICD-10 Finland
Alcohol depence active use
36.4
12.9
16
5
F10.25
ICD-10 Finland
Alcohol dependence continuous use
36.4
12.9
16
5
D01
ICPC
Abdominal pain/cramps general
4.5
12.9
41
123
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
5.6
12.9
28
61
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.8
12.8
22
38
S29
ICPC
Skin symptom/complaint other
4.2
12.5
46
154
T74.1
ICD-10 Finland
Physical abuse
13.8
12.4
21
18
N06AX16
ATC
venlafaxine; oral
4.2
12.4
45
149
P29
ICPC
Psychological sympt/compl other
4.5
12.3
38
111
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.9
12.3
58
230
ZXE00
NOMESCO Finland
One hour or less
4.0
12.2
81
403
P19
ICPC
Drug abuse
52.2
12.2
14
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
6.5
12.1
22
40
N05AX08
ATC
risperidone; systemic
5.8
12.0
25
52
N03AG01
ATC
valproic acid; systemic, rectal
6.0
12.0
24
48
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
33.8
12.0
15
5
Z72.2
ICD-10 Finland
Drug use
72.0
11.8
13
*
ZXD10
NOMESCO Finland
Scheduled procedure
3.7
11.8
67
299
N05CF01
ATC
zopiclone; oral
3.8
11.7
55
217
R2110
NOMESCO Finland
Giving the first information
5.3
11.7
27
62
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.7
11.3
75
367
Z3232
NOMESCO Finland
Midwife
3.7
11.2
52
202
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
10.1
11.1
22
26
U01
ICPC
Dysuria/painful urination
5.0
11.0
27
65
K05.31
ICD-10 Finland
Periodontitis pronounced
5.7
11.0
23
48
N05AX12
ATC
aripiprazole; systemic
5.9
11.0
22
44
P74
ICPC
Anxiety disorder/anxiety state
4.9
10.9
28
70
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
65.9
10.8
12
*
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
65.9
10.8
12
*
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
119.8
10.6
11
*
SPAT1265
SPAT
Breathalyser
119.8
10.6
11
*
X14
ICPC
Vaginal discharge
9.9
10.6
21
25
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
13.0
10.5
18
16
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
12.2
10.2
18
17
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
44.0
10.2
12
*
Z72.1
ICD-10 Finland
Alcohol use
28.8
10.0
13
5
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.7
10.0
43
157
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
8.8
9.9
21
28
X23
ICPC
Fear sexually transm dis female
3.8
9.9
38
129
X15
ICPC
Vaginal symptom/complaint other
4.7
9.7
26
67
EBA05
NOMESCO Finland
Complicated extraction of tooth
3.5
9.6
47
186
W14
ICPC
Contraception female other
4.0
9.6
33
103
RS122, ,
NOMESCO Finland
108.0
9.6
10
*
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
108.0
9.6
10
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.8
9.5
37
126
V03AA01, ,
ATC
+∞
9.5
9
*
RS312, ,
NOMESCO Finland
+∞
9.5
9
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.4
9.2
20
43
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.2
9.2
28
80
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
20.5
9.2
13
7
P01AB01
ATC
metronidazole; oral, rectal
3.2
9.1
78
428
F10.09
ICD-10 Finland
Alcohol intoxication UNS
26.3
9.1
12
5
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
3.3
9.0
49
206
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
7.4
9.0
21
33
IGY02
NOMESCO Finland
Psychiatric monitoring contact
5.2
9.0
20
44
XMA22
NOMESCO Finland
General examination of pregnant woman
3.7
8.9
35
120
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
29.9
8.6
11
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
12.0
8.6
15
14
Z3226
NOMESCO Finland
Physiotherapist
3.6
8.5
34
117
RS121, ,
NOMESCO Finland
96.4
8.5
9
*
RS310, ,
NOMESCO Finland
96.4
8.5
9
*
B17.1
ICD-10 Finland
Acute hepatitis C
+∞
8.4
8
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.0
8.4
27
80
EBA00
NOMESCO Finland
Extraction of tooth
3.0
8.4
66
341
K04.5
ICD-10 Finland
Chronic apical periodontitis
3.2
8.3
44
181
N06AX12
ATC
bupropion; oral
3.9
8.3
29
91
WX110, ,
SPAT
4.6
8.3
22
56
F61.0
ICD-10 Finland
Mixed personality disorders
11.2
8.3
15
15
L12
ICPC
Hand/finger symptom/complaint
3.3
8.1
40
158
EBA30
NOMESCO Finland
Extraction of root of tooth
10.5
8.0
15
16
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
5.1
7.9
18
40
K08.3
ICD-10 Finland
Retained dental root
7.6
7.9
18
27
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.7
7.9
20
49
N06AB10
ATC
escitalopram; oral
2.9
7.8
59
295
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
48.1
7.8
9
*
EB1SA, ,
SPAT
5.0
7.7
18
41
Z30.8
ICD-10 Finland
Other contraceptive management
4.6
7.7
20
50
F31.8
ICD-10 Finland
Other bipolar affective disorders
8.6
7.7
16
21
WX892
NOMESCO Finland
Monitored bed care
6.6
7.6
19
33
ZXD20
NOMESCO Finland
Day surgery
3.7
7.6
28
91
N06AB03
ATC
fluoxetine; oral
3.7
7.6
28
91
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
85.0
7.5
8
*
RS210, ,
NOMESCO Finland
85.0
7.5
8
*
P16
ICPC
Acute alcohol abuse
11.9
7.5
13
12
O80.0
ICD-10 Finland
Spontaneous vertex delivery
3.1
7.5
88
554
N03AX09
ATC
lamotrigine; oral
4.3
7.4
21
56
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
17.1
7.4
11
7
RS311, ,
NOMESCO Finland
+∞
7.4
7
*
W01
ICPC
Question of pregnancy
9.7
7.3
14
16
N05AF03
ATC
chlorprothixene; systemic
9.7
7.3
14
16
N05BA02
ATC
chlordiazepoxide; systemic
21.6
7.3
10
5
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
32.1
7.3
9
*
R02
ICPC
Shortness of breath/dyspnoea
3.8
7.2
25
78
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.0
7.1
41
176
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
14.9
7.0
11
8
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
11.9
7.0
12
11
W79
ICPC
Unwanted pregnancy
6.6
6.9
17
29
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
42.5
6.8
8
*
Z30.0
ICD-10 Finland
General counselling and advice on contraception
3.3
6.8
30
109
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.9
6.8
22
65
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
24.1
6.8
9
*
N06AB06
ATC
sertraline; oral
3.1
6.8
34
134
D19
ICPC
Teeth/gum symptom/complaint
2.7
6.8
65
362
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
9.5
6.7
13
15
OAA68, ,
SPAT
10.9
6.7
12
12
D12
ICPC
Constipation
10.9
6.7
12
12
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.0
6.6
37
155
IGY99
NOMESCO Finland
Other psychiatric treatment contact
6.2
6.6
17
31
P76
ICPC
Depressive disorder
3.3
6.5
29
106
SPAT1324
SPAT
Screening procedure
0.2
6.5
5
263
F60.2
ICD-10 Finland
Dissocial personality disorder
73.5
6.5
7
*
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
10.1
6.4
12
13
P17
ICPC
Tobacco abuse
11.9
6.4
11
10
N05CD07
ATC
temazepam; oral
6.4
6.4
16
28
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.8
6.3
21
63
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
28.3
6.3
8
*
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
28.3
6.3
8
*
Z10.1
ICD-10 Finland
Routine general health check-up of inhabitants of institutions
+∞
6.3
6
*
ICC03
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric ward
+∞
6.3
6
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
6.2
6.2
16
29
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
6.7
6.2
15
25
Z71.8
ICD-10 Finland
Other specified counselling
2.6
6.1
70
418
U02
ICPC
Urinary frequency/urgency
3.1
6.1
30
116
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
6.4
6.1
15
26
B86
ICD-10 Finland
Scabies
7.0
6.1
14
22
A46
ICD-10 Finland
Erysipelas
4.0
6.0
18
50
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.2
6.0
27
99
WX110
NOMESCO Finland
Infiltration anesthesia
4.0
6.0
110
833

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
68
9.18
28.23
2.8
1.5
0.31
0.27
mg/l
0.15
34
27
46
85
8.05
26.19
6.1
2.0
—
—
—
0
0
39
62
8.75
25.29
3.1
1.5
—
—
—
0
0
45
106
6.12
19.62
3.4
2.6
28.68
29.08
u/l
0.04
37
90
44
108
5.79
18.21
4.0
1.5
—
—
—
0
0
45
114
5.65
17.95
3.9
1.5
—
—
—
0
0
45
115
5.59
17.76
3.9
1.5
—
—
—
0
0
45
116
5.54
17.56
3.8
1.5
—
—
—
0
0
44
115
5.40
16.83
4.0
1.5
—
—
—
0
0
39
95
5.55
16.10
3.0
1.5
—
—
—
0
0
46
141
4.61
14.24
1.8
1.4
—
—
—
0
0
22
34
7.66
14.18
1.4
1.4
—
—
—
0
0
44
132
4.63
13.97
2.5
1.8
—
—
—
0
0
27
56
5.90
13.10
7.4
7.1
—
—
—
0
0
62
251
3.96
12.90
3.2
2.4
0.22
0.41
e6/l
0.54
46
170
43
134
4.40
12.89
2.9
2.2
5.53
4.43
e6/l
0.19
17
53
65
304
3.41
10.31
3.2
2.5
14.77
66.00
e6/l
1.55
51
223
75
388
3.39
9.98
4.9
3.2
37.22
54.42
e6/l
0.31
49
240
63
300
3.25
9.52
5.7
5.6
—
—
—
0
0
45
177
3.43
9.27
6.1
4.0
—
—
—
0
0
86
498
3.42
9.21
3.2
2.2
—
—
—
0
0
58
273
3.13
8.78
4.5
3.1
6.17
8.15
mmol/l
2.64
52
241
20
46
5.00
8.51
3.5
4.8
24.59
25.24
mmol/l
0.25
20
46
35
127
3.45
8.07
2.1
2.0
—
—
—
0
0
14
13
11.98
8.03
1.8
1.2
—
—
—
0
0
74
420
2.91
7.71
2.3
1.8
—
—
—
0
0
29
96
3.64
7.66
1.7
1.3
—
—
—
0
0
51
238
2.95
7.64
2.5
1.5
—
—
—
0
0
41
172
3.08
7.39
2.1
2.2
509.34
547.94
mosm/kgh2o
0.38
32
144
43
199
2.78
6.37
2.0
2.3
13.85
15.83
e6/l
0.13
35
175
21
64
3.75
6.19
4.1
2.7
7.38
7.38
ph
—
6
36
18
49
4.13
6.18
14.4
8.3
7.40
7.42
ph
—
6
26
22
73
3.45
5.72
14.8
6.6
104.91
105.34
mmol/l
0.14
22
73
29
119
2.88
5.29
1.3
1.6
—
—
—
0
0
45
232
2.48
5.22
2.8
3.6
7.41
7.40
ph
0.64
27
162
48
255
2.45
5.22
4.5
3.2
—
—
—
0
0
26
524
0.36
5.22
1.8
2.3
—
—
—
0
0
60
355
2.35
5.10
5.5
5.6
—
—
—
0
0
28
115
2.86
5.09
1.3
1.5
1.12
1.33
mm
1.61
20
85
28
116
2.83
5.00
1.3
1.5
—
—
—
0
0
32
143
2.67
4.95
3.4
2.4
42.14
223.47
ng/l
0.46
14
55
13
27
5.25
4.65
16.2
12.4
0.52
0.62
%
0.35
13
27
75
502
2.27
4.60
5.1
2.9
5.93
6.20
ph
1.20
35
286
80
551
2.29
4.57
6.7
4.0
6.18
6.04
mmol/l
0.28
75
487
13
28
5.06
4.52
16.2
12.2
1.66
0.85
%
0.93
13
28
75
508
2.22
4.39
7.3
8.6
0.00
0.00
e9/l
0.50
50
404
16
51
3.46
4.39
1.6
1.9
—
—
—
0
0
90
659
2.36
4.33
12.5
8.5
4.14
3.92
e9/l
0.43
68
577
13
30
4.72
4.27
16.2
11.6
88.78
95.74
%
0.60
13
30
53
316
2.19
4.24
3.7
2.1
—
—
—
0
0
99
760
2.55
4.21
8.8
7.1
83.90
71.26
u/l
1.32
92
719
12
28
4.63
3.94
1.2
1.0
—
—
—
0
0
27
124
2.51
3.90
1.3
1.2
—
—
—
0
0
77
544
2.11
3.85
5.9
5.6
2.37
2.76
%
1.07
71
516
77
545
2.10
3.82
5.9
5.6
7.49
8.01
%
1.15
71
518
77
545
2.10
3.82
5.9
5.6
0.60
0.67
%
0.52
71
512
13
325
0.33
3.78
2.5
4.4
—
—
—
0
0
30
150
2.32
3.59
1.3
1.6
74.50
57.84
ug/l
0.93
22
128
45
268
2.07
3.49
4.4
2.9
1.01
1.02
kg/l
1.05
25
167
11
27
4.37
3.49
1.2
1.0
—
—
—
0
0
8
15
5.62
3.25
1.9
1.8
72.00
59.83
%
—
8
15
75
551
1.93
3.07
2.5
2.7
—
—
estimate
—
0
0
79
592
1.93
3.03
6.0
5.7
0.04
0.04
e9/l
0.03
59
517
79
592
1.93
3.03
6.0
5.6
0.55
0.52
e9/l
0.55
58
521
5
5
10.34
3.00
1.2
1.0
—
—
—
0
0
13
296
0.37
2.99
1.4
1.6
—
—
—
0
0
76
564
1.91
2.98
6.0
5.6
29.20
29.73
%
0.19
71
542
75
555
1.90
2.96
6.1
5.5
57.26
56.90
%
0.12
70
534
81
619
1.90
2.85
6.1
6.0
0.16
0.18
e9/l
0.59
61
558
21
101
2.30
2.72
1.4
1.6
1306.17
1050.05
nmol/l
0.40
12
80
53
360
1.83
2.67
3.8
2.6
—
0.00
—
0
5
79
610
1.82
2.57
6.0
5.7
2.10
1.97
e9/l
0.86
61
552
44
285
1.85
2.56
8.0
6.4
1.11
1.04
inr
0.47
28
235
9
26
3.65
2.54
1.1
1.4
—
—
—
0
0
10
33
3.21
2.42
7.0
2.2
0.54
0.57
%
—
10
33
22
379
0.49
2.41
2.5
2.5
0.33
0.04
estimate
—
6
112
5
8
6.45
2.39
2.2
2.3
12.50
10.85
%
—
5
8
10
34
3.11
2.34
7.0
2.1
2.23
1.49
%
—
10
34
6
13
4.79
2.30
1.8
1.2
—
—
—
0
0
51
357
1.73
2.24
2.2
2.1
—
—
—
0
0
57
412
1.71
2.23
1.9
1.8
99.53
98.09
pmol/l
0.06
21
236
22
118
2.05
2.19
2.0
1.5
—
—
—
0
0
8
25
3.35
2.13
1.8
2.2
—
—
—
0
0
5
10
5.16
2.09
1.6
1.8
—
—
—
0
0
26
154
1.87
1.96
2.5
1.9
2.43
2.39
mmol/l
0.99
21
138
40
271
1.71
1.93
2.1
1.8
0.85
0.96
mg/l
0.11
29
204
19
323
0.51
1.93
4.1
3.3
0.00
0.01
estimate
—
7
128
7
22
3.31
1.91
4.7
3.1
13.29
17.25
u/ml
—
7
22
111
993
2.21
1.87
4.4
3.5
5.97
5.56
mmol/l
1.38
102
945
93
789
1.73
1.84
6.1
4.2
—
—
—
0
0
5
13
3.96
1.73
25.6
17.5
1451.20
1856.23
nmol/l
—
5
13
19
109
1.88
1.58
1.4
1.5
404.41
272.55
mu/l
0.59
19
98
50
379
1.54
1.48
2.0
1.8
—
—
—
0
0
9
39
2.41
1.46
1.1
1.3
—
—
—
0
0
117
1099
2.32
1.38
20.0
11.5
29.53
17.43
mg/l
2.41
102
854
5
17
3.02
1.37
21.8
4.1
—
—
—
0
0
55
434
1.48
1.32
1.7
1.8
—
—
—
0
0
8
34
2.44
1.32
1.0
1.4
—
—
—
0
0
5
18
2.85
1.29
1.8
2.4
7.41
7.44
ph
—
5
18
44
338
1.47
1.18
1.3
1.4
2.71
1.97
g/l
1.13
19
233
0
35
0.00
1.17
0.0
1.3
—
305.78
—
0
27
10
179
0.52
1.17
1.4
1.3
—
—
—
0
0
5
20
2.56
1.16
1.2
1.4
—
—
—
0
0
22
145
1.63
1.16
1.2
1.2
—
—
—
0
0
21
140
1.60
1.06
1.0
1.1
—
—
—
0
0
123
1202
+∞
0.99
30.0
17.8
265.81
270.70
e9/l
0.41
118
1192
7
37
1.94
0.95
1.1
1.2
—
—
—
0
0
8
45
1.83
0.86
2.1
1.6
—
—
—
0
0
32
245
1.41
0.86
1.3
1.5
904.80
946.93
mu/l
0.10
24
206
6
31
1.98
0.85
1.2
3.3
—
—
—
0
0
12
73
1.71
0.85
1.0
1.2
—
—
—
0
0
0
26
0.00
0.79
0.0
1.2
—
30.62
—
0
21
123
1204
+∞
0.79
29.9
17.7
4.38
4.46
e12/l
1.61
118
1193
123
1204
+∞
0.79
29.9
17.8
7.43
6.83
e9/l
1.88
118
1189
57
486
1.32
0.77
2.0
1.9
—
—
—
0
0
9
53
1.75
0.77
1.7
1.8
—
8.38
—
0
16
6
108
0.53
0.76
3.7
3.0
—
—
—
0
0
5
24
2.13
0.75
2.4
3.0
—
—
—
0
0
7
38
1.89
0.75
1.0
1.1
—
—
—
0
0
11
68
1.68
0.74
1.1
1.3
—
—
—
0
0
5
25
2.04
0.73
2.0
4.4
24.44
23.55
mmol/l
—
5
25
102
951
1.42
0.72
3.9
5.1
13.53
14.22
pmol/l
3.09
95
906
5
27
1.89
0.69
1.4
4.8
—
—
—
0
0
19
138
1.45
0.67
1.2
1.2
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
9
135
0.64
0.55
1.7
1.7
—
—
—
0
0
6
99
0.59
0.54
1.2
1.1
—
—
—
0
0
68
613
1.24
0.54
4.2
3.3
233.37
0.00
estimate
—
8
132
21
264
0.75
0.51
1.5
1.3
1.06
7.10
u/ml
—
5
109
25
204
1.28
0.45
3.3
4.2
5.77
13.69
mg/mmol
0.84
13
131
7
102
0.67
0.41
3.3
2.0
—
0.00
estimate
—
0
24
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.27
—
0
8
0
16
0.00
0.41
0.0
1.9
—
131.36
—
0
11
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
96
912
1.24
0.40
5.2
4.2
35.46
36.55
mmol/mol
0.58
90
887
48
428
1.20
0.40
1.7
1.7
1.82
1.33
mmol/l
0.75
43
395
6
41
1.49
0.36
1.0
1.1
—
—
—
0
0
17
208
0.79
0.34
2.4
2.3
130.18
69.26
ug/g
0.33
11
159
13
164
0.77
0.33
2.5
2.2
6773.11
7370.67
u/l
—
7
70
24
204
1.22
0.32
3.1
3.6
36.69
88.94
mg/l
0.83
12
137
66
615
1.16
0.30
4.4
3.3
0.00
0.00
estimate
—
7
127
30
264
1.18
0.28
2.1
2.9
23.24
11.87
ng/l
0.43
11
88
65
608
1.15
0.28
4.3
3.2
0.00
0.01
estimate
—
7
133
25
284
0.85
0.25
1.4
1.3
15.77
22.45
iu/ml
—
6
79
6
82
0.72
0.25
1.0
1.1
—
46.00
—
0
5
107
1041
1.21
0.24
3.9
3.9
2.86
2.83
mmol/l
0.14
101
1008
5
41
1.23
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
73.82
—
0
11
0
10
0.00
0.21
0.0
2.8
—
0.99
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
2.07
—
0
12
0
13
0.00
0.21
0.0
6.0
—
90.88
—
0
6
0
13
0.00
0.21
0.0
1.1
—
112.77
—
0
13
0
13
0.00
0.21
0.0
1.6
—
47.04
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
10
121
0.81
0.19
2.1
1.8
416.30
385.74
nmol/l
—
10
116
6
75
0.79
0.16
1.7
2.1
0.05
0.15
e6/l
—
6
70
7
87
0.79
0.15
1.3
1.1
—
—
—
0
0
9
108
0.82
0.13
2.0
2.3
—
17.66
—
0
12
10
116
0.85
0.12
1.2
1.4
—
—
—
0
0
7
64
1.10
0.08
1.6
2.4
—
3.90
—
0
16
9
83
1.09
0.07
1.1
1.1
—
—
—
0
0
9
103
0.86
0.06
1.2
1.3
84.58
336.26
u/ml
—
9
95
22
210
1.06
0.04
2.0
2.8
—
—
—
0
0
17
176
0.96
0.00
1.6
1.3
24.22
21.21
iu/l
—
10
159
96
966
0.97
0.00
2.8
3.1
1.26
1.17
mmol/l
0.67
87
922
13
126
1.04
0.00
1.5
1.3
—
—
—
0
0
104
1037
1.02
0.00
3.3
3.6
1.48
1.52
mmol/l
0.34
96
1005
104
1038
1.01
0.00
3.4
3.7
4.71
4.76
mmol/l
0.23
97
1008
20
198
1.01
0.00
1.7
2.2
—
—
—
0
0
10
98
1.02
0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
1.17
—
0
7
0
7
0.00
0.00
0.0
2.7
—
8.29
—
0
7
0
7
0.00
0.00
0.0
2.6
—
3.77
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
104.86
—
0
7
0
8
0.00
0.00
0.0
1.6
—
23.64
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
257.56
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
506.60
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
58.20
—
0
5
0
9
0.00
-0.00
0.0
2.7
—
16.56
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
6.48
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
0.95
—
0
9
0
5
0.00
-0.00
0.0
2.8
—
2110.00
—
0
5
0
5
0.00
-0.00
0.0
34.0
—
5.46
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
0.02
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
28.40
—
0
5
5
49
1.02
-0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
24.00
—
0
5
9
98
0.91
-0.00
1.1
1.3
—
27.29
—
0
7
0
9
0.00
-0.00
0.0
2.8
—
6.37
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
25.33
—
0
6
0
6
0.00
-0.00
0.0
2.2
—
142.33
—
0
6
0
6
0.00
-0.00
0.0
3.2
—
1.58
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
91.83
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint MATERNCAREFETUSALCO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have MATERNCAREFETUSALCO.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: MATERNCAREFETUSALCO – Maternal care for (suspected) damage to fetus from alcohol

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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