≡ Risteys
R14

Documentation Changelog GitHub Contact & Feedback

Histrionic personality disorder

DOID EFO Endpoint Browser PheWeb

F5_HISPER

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F60.4
  • Hospital discharge: ICD-9 — 3015
  • Hospital discharge: ICD-8 — 3015
  • Cause of death: ICD-10 — F60.4
  • Cause of death: ICD-9 — 3015
  • Cause of death: ICD-8 — 3015

2 out of 7 registries used, show all original rules.

201

4. Check minimum number of events

None

201

5. Include endpoints

None

201

6. Filter based on genotype QC (FinnGen only)

174

Control definitions (FinnGen only)

Control exclude
F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F60
Name in latin
Personalitas histrionica

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1630 1108 491
Only index persons 1208 870 338
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.01
Only index persons 0.03 0.03 0.01
Median age at first event (years)
Whole population 37.99 39.56 33.95
Only index persons 35.62 37.32 31.25

-FinnGen-

Key figures

All Female Male
Number of individuals 174 128 46
Unadjusted period prevalence (%) 0.04 0.05 0.02
Median age at first event (years) 31.41 30.81 33.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
181
Matched controls
1810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
35.5
116.8
85
44
F60.4
ICD-10 Finland
Histrionic personality disorder
+∞
104.6
90
*
30150
ICD-8 Finland
Personality disorders, Hysterical
+∞
80.3
71
*
N05AA02
ATC
levomepromazine; systemic
35.1
75.8
51
20
T36
ICD-10 Finland
Poisoning by systemic antibiotics
30.7
68.4
48
21
N05AH04
ATC
quetiapine; oral
11.8
64.4
105
190
N05AH03
ATC
olanzapine; systemic
17.4
62.3
59
49
N05AB03
ATC
perphenazine; systemic, rectal
31.9
61.2
42
17
N03AG01
ATC
valproic acid; systemic, rectal
17.6
60.1
56
45
N05AX08
ATC
risperidone; systemic
14.2
54.3
58
58
N03AE01
ATC
clonazepam; systemic
17.3
51.4
47
36
N05CD07
ATC
temazepam; oral
10.8
48.4
65
89
N05BA01
ATC
diazepam; systemic, rectal
9.2
46.2
75
129
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
503.8
41.9
40
*
N06AB04
ATC
citalopram; systemic
7.5
41.6
94
227
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
15.3
40.6
39
32
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
14.4
40.1
40
35
F61.0
ICD-10 Finland
Mixed personality disorders
+∞
35.6
33
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
9.5
34.9
48
66
F29
ICD-10 Finland
Unspecified nonorganic psychosis
14.7
34.2
33
27
N06AX03
ATC
mianserin; oral
13.3
33.9
35
32
N06AB03
ATC
fluoxetine; oral
7.4
33.9
63
122
F60.9
ICD-10 Finland
Personality disorder, unspecified
+∞
33.4
31
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
7.2
33.3
64
128
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
389.3
33.0
32
*
P29
ICPC
Psychological sympt/compl other
9.0
32.2
46
66
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
10.1
32.1
41
51
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
13.2
32.0
33
30
N06AX16
ATC
venlafaxine; oral
6.4
31.7
72
169
N05AX12
ATC
aripiprazole; systemic
14.2
31.6
31
26
N03AX09
ATC
lamotrigine; oral
11.7
30.4
34
35
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
6.9
28.5
54
105
N05BA06
ATC
lorazepam; systemic, sublingual
10.0
28.4
36
44
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
7.4
28.0
48
84
N06AA09
ATC
amitriptyline; systemic
7.0
27.2
50
94
N05BA04
ATC
oxazepam; oral
5.2
27.2
101
355
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
33.0
27.0
35
13
N05AN01
ATC
lithium; oral
31.8
26.0
34
13
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
288.2
25.3
25
*
3015A
ICD-9 Finland
Personality disorders, Histrionic personality disorder[HUOMIONHAKUINEN PERSOONALLISUUS]
+∞
23.4
22
*
N04AA02
ATC
biperiden; systemic
91.8
22.3
24
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
23.7
21.2
30
15
N05AF03
ATC
chlorprothixene; systemic
26.3
21.2
29
13
N06AX11
ATC
mirtazapine; oral
4.3
20.9
106
450
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
7.3
20.2
33
54
N06AB06
ATC
sertraline; oral
5.1
20.1
52
132
N07BB01
ATC
disulfiram; oral
9.5
19.8
25
30
F34.1
ICD-10 Finland
Dysthymia
8.0
17.9
26
37
SPAT1254
SPAT
Administration of medicine
4.8
17.7
48
126
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
99.4
16.9
18
*
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
99.4
16.9
18
*
P99
ICPC
Psychological disorders other
14.8
16.8
28
22
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
+∞
15.9
15
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.7
15.3
26
44
N05AD01
ATC
haloperidol; systemic
18.6
15.2
23
14
SPAT1307
SPAT
Psychosocial counselling and guidance
6.6
14.9
26
45
F31.8
ICD-10 Finland
Other bipolar affective disorders
19.1
14.7
22
13
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
24.8
14.6
20
9
N05BA12
ATC
alprazolam; oral
4.6
14.4
39
101
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.3
14.2
32
71
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
58.1
14.1
16
*
N05BE01
ATC
buspirone; oral
12.4
14.0
25
23
SPAT1240
SPAT
Therapeutic discussion
4.3
14.0
42
118
N06AX12
ATC
bupropion; oral
5.9
13.9
27
52
N03AX16
ATC
[U] pregabalin
3.5
13.7
67
263
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
28.3
13.7
18
7
30010
ICD-8 Finland
Neuroses, Hysterical neurosis
150.8
13.6
14
*
N06AA12
ATC
doxepin; systemic
5.6
13.6
28
57
N02AX02
ATC
tramadol; systemic, rectal
3.2
13.3
109
579
N05AD03
ATC
melperone; systemic
54.1
13.1
15
*
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
34.8
12.8
16
5
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
14.7
12.8
21
16
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
75.3
12.8
14
*
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
4.4
12.7
36
96
F60.0
ICD-10 Finland
Paranoid personality disorder
+∞
12.6
12
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.7
12.6
49
165
S06.0
ICD-10 Finland
Concussion
4.2
12.5
39
112
R56.8
ICD-10 Finland
Other and unspecified convulsions
6.1
12.5
23
42
N05AC02
ATC
thioridazine; oral
17.5
12.4
19
12
N05CF01
ATC
zopiclone; oral
3.1
12.4
84
396
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
40.6
12.4
15
*
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
29.0
12.3
16
6
N06AB10
ATC
escitalopram; oral
3.3
12.2
65
266
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
50.2
12.1
14
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
18.0
11.9
18
11
N05AF05
ATC
zuclopenthixol; systemic
69.6
11.8
13
*
30180
ICD-8 Finland
Personality disorders, Immatura
69.6
11.8
13
*
F60.8
ICD-10 Finland
Other specific personality disorders
127.8
11.6
12
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
11.2
45
154
F60.5
ICD-10 Finland
Anankastic personality disorder
46.3
11.1
13
*
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
46.3
11.1
13
*
D01AC02
ATC
miconazole; topical
4.6
10.9
28
69
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
23.2
10.9
15
7
A06AD11
ATC
lactulose; oral
3.7
10.8
40
129
R60.9
ICD-10 Finland
Oedema, unspecified
5.6
10.8
22
44
N03AX11
ATC
topiramate; oral
11.6
10.6
19
18
P80
ICPC
Personality disorder
116.5
10.5
11
*
30188
ICD-8 Finland
Personality disorders, Alia definita
+∞
10.5
10
*
30041
ICD-8 Finland
Neuroses, Depressiva
20.3
10.5
15
8
N03AF02
ATC
oxcarbazepine; oral
9.0
10.2
21
26
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
42.6
10.1
12
*
N06AB08
ATC
fluvoxamine; oral
13.3
10.1
17
14
F20.9
ICD-10 Finland
Schizophrenia, unspecified
13.3
10.1
17
14
30000
ICD-8 Finland
Neuroses, Anxiety neurosis
21.5
10.0
14
7
L28
ICPC
Limited function/disability (L)
3.1
9.9
53
215
P72
ICPC
Schizophrenia
12.4
9.8
17
15
29999
ICD-8 Finland
Unspecified psychosis
58.2
9.8
11
*
P19
ICPC
Drug abuse
58.2
9.8
11
*
R06.0
ICD-10 Finland
Dyspnoea
2.8
9.7
73
355
J45.9
ICD-10 Finland
Asthma, unspecified
3.0
9.6
53
218
AA1AD
NOMESCO Finland
CT of head and brain
2.8
9.6
70
335
K08.3
ICD-10 Finland
Retained dental root
4.5
9.6
25
62
N06AX26
ATC
vortioxetine; oral
4.5
9.6
25
62
N06AA04
ATC
clomipramine; systemic
13.4
9.6
16
13
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
5.4
9.6
20
41
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
10.4
9.5
18
19
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.7
9.1
72
358
F39
ICD-10 Finland
Unspecified mood [affective] disorder
15.0
8.8
14
10
IGY02
NOMESCO Finland
Psychiatric monitoring contact
9.7
8.8
17
19
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.6
8.7
32
102
F10.20
ICD-10 Finland
Alcohol dependence currently independent
17.4
8.7
13
8
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.2
8.6
38
137
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
13.7
8.5
14
11
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
10.2
8.5
16
17
29580
ICD-8 Finland
Schizophrenia, Other
+∞
8.4
8
*
3015B
ICD-9 Finland
Personality disorders, Histrionic personality disorder[ITSEAIHEUTETTU HÄIRIÖ,RUUMIILLISIN OIREIN]
+∞
8.4
8
*
30199
ICD-8 Finland
Personality disorders, Unspecified
+∞
8.4
8
*
9690A
ICD-9 Finland
Poisoning by psychotropic agents, Antidepressants
+∞
8.4
8
*
P76
ICPC
Depressive disorder
4.0
8.3
25
69
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
15.4
8.3
13
9
N05AF01
ATC
flupentixol; systemic
15.4
8.3
13
9
F41.1
ICD-10 Finland
Generalized anxiety disorder
4.5
8.2
21
51
N05AB01
ATC
dixyrazine; systemic
18.2
8.2
12
7
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
35.1
8.2
10
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
35.1
8.2
10
*
SPAT1229
SPAT
Assessment of need for aid
4.3
8.2
22
56
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
23.3
8.1
11
5
SPAT1234
SPAT
Support of social functional capacity
4.8
8.1
19
43
K59.09
ICD-10 Finland
Constipation, unspecified
4.0
8.0
24
66
N06AG02
ATC
moclobemide; oral
6.9
8.0
19
30
C07AA05
ATC
propranolol; systemic
2.7
8.0
56
260
N05CD02
ATC
nitrazepam; oral
11.6
7.9
14
13
A28
ICPC
Limited function/disability NOS
2.9
7.9
44
181
U04
ICPC
Incontinence urine
4.5
7.8
20
49
A46
ICD-10 Finland
Erysipelas
3.1
7.7
38
145
IGY02, ,
SPAT
19.4
7.7
11
6
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
19.4
7.7
11
6
SPAT1260
SPAT
Consultation of another employee
2.9
7.7
44
183
D12
ICPC
Constipation
7.7
7.7
17
24
N06AB05
ATC
paroxetine; oral
4.3
7.7
21
54
F22.0
ICD-10 Finland
Delusional disorder
26.3
7.7
10
*
N03AX12
ATC
[U] gabapentin; oral
2.8
7.7
47
203
U01
ICPC
Dysuria/painful urination
3.8
7.6
25
74
188
Kela drug reimbursment
Psychosis requiring demanding treatment
83.4
7.5
8
*
Z72.8
ICD-10 Finland
Other problems related to lifestyle
83.4
7.5
8
*
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
83.4
7.5
8
*
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
83.4
7.5
8
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.0
7.4
38
149
E000001, ,
ATC
2.7
7.4
50
227
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
4.8
7.3
17
38
M54.5
ICD-10 Finland
Low back pain
2.4
7.3
84
486
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
16.6
7.3
11
7
N05AA01
ATC
chlorpromazine; systemic, rectal
21.0
7.2
10
5
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
7.2
39
157
E66.8
ICD-10 Finland
Other obesity
4.5
7.2
18
43
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.6
7.1
25
77
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.8
7.1
42
177
R03BA05
ATC
fluticasone; inhalant
2.7
7.1
47
210
P01
ICPC
Feeling anxious/nervous/tense
2.9
7.1
39
158
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
7.1
57
281
IGY99
NOMESCO Finland
Other psychiatric treatment contact
9.9
6.9
13
14
N06AX22
ATC
agomelatine; oral
9.9
6.9
13
14
P18
ICPC
Medication abuse
41.7
6.8
8
*
W19
ICD-10 Finland
Unspecified fall
3.4
6.8
26
85
M01AG02
ATC
tolfenamic acid; oral, rectal
2.8
6.8
39
162
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
6.8
69
377
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
23.5
6.7
9
*
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
23.5
6.7
9
*
SPAT1301
SPAT
No procedures
2.3
6.7
68
370
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.6
6.7
44
196
Z29
ICPC
Social problem NOS
9.2
6.7
13
15
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
7.3
6.7
15
22
Z02.7
ICD-10 Finland
Issue of medical certificate
3.5
6.6
24
76
R02
ICPC
Shortness of breath/dyspnoea
2.8
6.6
37
152
U05
ICPC
Urination problems other
5.6
6.5
18
35
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.4
6.5
16
27
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
72.3
6.5
7
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
8.7
6.5
13
16
N03AF01
ATC
carbamazepine; oral, rectal
4.1
6.4
18
47
N06AX21
ATC
duloxetine; oral
2.8
6.4
35
141
C03CA01
ATC
furosemide; systemic
2.3
6.4
62
330
R03BB04
ATC
tiotropium bromide; inhalant
3.5
6.4
23
72
R05
ICPC
Cough
2.3
6.4
64
346
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.8
6.4
20
57
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
6.2
6.3
16
28
F60.7
ICD-10 Finland
Dependent personality disorder
+∞
6.3
6
*
Z72.2
ICD-10 Finland
Drug use
+∞
6.3
6
*
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
+∞
6.3
6
*
F60.2
ICD-10 Finland
Dissocial personality disorder
+∞
6.3
6
*
F61
ICD-10 Finland
Mixed and other personality disorders
+∞
6.3
6
*
34599
ICD-8 Finland
Epilepsy, Other and unspecified
27.7
6.3
8
*
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.4
6.2
16
39
J01EA01
ATC
trimethoprim; systemic
2.3
6.2
62
334
F40.1
ICD-10 Finland
Social phobias
9.1
6.2
12
14
M79.0
ICD-10 Finland
Rheumatism, unspecified
6.4
6.1
15
25
ZYC01
NOMESCO Finland
Remote contact by phone
3.6
6.1
21
64
A05
ICPC
Feeling ill
3.8
6.1
19
54
F32.1
ICD-10 Finland
Moderate depressive episode
3.8
6.1
19
54
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
6.1
66
368
P15
ICPC
Chronic alcohol abuse
7.7
6.0
13
18
ZY010
NOMESCO Finland
Hospital outpatient
4.3
6.0
16
40
SPAT1262
SPAT
Handing over of treatment supplies
2.6
6.0
38
165
OAB43, ,
SPAT
0.2
6.0
12
407

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
32
11.04
26.04
4.0
1.8
—
—
—
0
0
27
40
7.76
17.95
3.3
1.3
—
—
—
0
0
30
52
6.72
17.28
3.1
1.5
—
—
—
0
0
30
52
6.72
17.28
3.1
1.5
—
—
—
0
0
30
53
6.59
16.96
3.1
1.5
—
—
—
0
0
30
53
6.59
16.96
3.1
1.5
—
—
—
0
0
28
55
5.84
14.15
3.2
1.5
—
—
—
0
0
24
22
12.39
13.49
2.9
1.4
—
—
—
0
0
97
512
2.93
11.47
3.4
2.4
57.42
65.56
u/l
0.44
89
484
13
5
27.81
9.96
16.8
7.8
0.60
0.64
mmol/l
—
13
5
138
933
3.02
9.46
6.5
4.7
6.63
6.56
mmol/l
0.13
131
879
25
68
4.11
8.51
1.9
1.3
0.27
0.39
mg/l
—
9
26
74
387
2.54
8.28
5.5
3.9
1.02
1.02
kg/l
0.08
46
248
62
301
2.61
8.06
1.9
1.7
423.73
459.20
pmol/l
0.50
49
260
87
498
2.44
7.93
2.8
2.1
161.71
152.86
u/l
0.13
82
479
121
804
2.52
7.90
5.9
6.9
1.22
1.22
mmol/l
0.02
104
707
127
867
2.56
7.75
5.6
6.7
9.55
10.67
umol/l
0.78
117
828
27
86
3.51
7.34
3.2
4.7
—
—
—
0
0
111
725
2.37
7.30
6.1
5.9
1.22
1.22
mmol/l
0.08
104
675
80
458
2.34
7.10
1.7
1.6
18.24
22.06
nmol/l
1.45
70
390
40
168
2.77
6.81
4.0
7.7
7.38
7.42
ph
1.55
23
106
107
711
2.24
6.45
2.4
2.1
93.57
99.54
pmol/l
0.52
52
346
72
410
2.26
6.33
5.3
4.3
—
—
—
0
0
39
170
2.65
6.15
4.1
7.6
5.29
5.13
kpa
0.53
39
165
105
703
2.18
6.08
4.8
4.5
35.20
36.16
g/l
0.94
96
666
39
172
2.62
6.00
4.1
7.6
1.65
1.05
mmol/l
0.54
31
145
17
46
3.98
5.79
3.8
3.9
3.91
3.81
mmol/l
0.30
17
46
85
534
2.12
5.70
3.8
3.2
6.31
7.79
mmol/l
2.40
72
450
30
119
2.82
5.64
3.2
2.4
6.83
5.04
ug/l
0.16
24
106
44
212
2.42
5.61
5.3
6.6
105.27
104.41
mmol/l
0.54
44
212
65
370
2.18
5.60
2.2
1.7
0.73
1.12
mg/l
1.61
52
296
92
599
2.09
5.58
6.5
3.4
49.84
34.35
ng/l
0.26
70
405
153
1222
2.63
5.45
9.1
8.4
85.60
77.80
u/l
0.79
147
1163
36
163
2.51
5.22
3.7
3.1
7.36
7.39
ph
1.41
24
106
81
513
2.05
5.20
6.5
3.0
—
—
—
0
0
47
242
2.27
5.12
2.4
1.6
1097.37
1225.45
nmol/l
0.48
35
181
16
38
4.52
4.96
1.9
2.4
25.40
24.54
mmol/l
0.29
16
38
21
73
3.12
4.95
6.5
4.1
36.93
36.94
°c
0.03
21
73
142
1125
2.22
4.70
5.5
3.1
57.80
45.09
u/l
0.79
130
1076
82
538
1.96
4.63
4.2
5.9
—
—
—
0
0
67
411
2.00
4.59
2.1
2.1
2.87
3.09
mg/l
0.29
57
358
103
735
1.93
4.49
4.9
3.4
6.42
6.18
ph
1.19
53
415
102
730
1.91
4.36
17.5
11.1
1.20
1.20
inr
0.01
89
590
47
273
1.97
3.66
2.3
3.2
0.85
0.80
mmol/l
1.37
40
258
51
306
1.93
3.61
4.1
2.8
476.84
544.00
mosm/kgh2o
1.13
44
262
23
100
2.49
3.61
4.7
8.7
0.67
0.69
%
0.08
23
100
27
127
2.32
3.58
4.5
7.8
—
—
—
0
0
73
493
1.81
3.56
6.6
3.7
0.00
0.00
estimate
-0.00
28
162
119
929
1.82
3.54
10.7
10.8
4.45
3.98
e9/l
1.42
104
817
23
101
2.46
3.53
4.7
8.7
2.48
1.23
%
2.61
23
101
87
623
1.76
3.45
5.4
3.9
221.30
62.95
e6/l
0.60
67
417
46
271
1.94
3.42
2.3
2.3
11.12
13.04
umol/l
1.21
41
260
102
774
1.73
3.23
5.3
6.1
57.39
57.16
%
0.06
95
735
68
461
1.76
3.21
3.9
3.1
0.38
0.39
e6/l
0.02
58
324
77
541
1.74
3.21
4.8
3.2
127.26
55.14
e6/l
0.50
68
403
73
506
1.74
3.19
2.8
4.0
7.40
7.40
ph
0.09
51
359
16
63
2.69
3.05
3.0
5.6
0.92
0.86
%
0.22
16
58
7
12
6.02
3.05
12.1
17.8
850.43
768.25
nmol/l
—
7
12
6
191
0.29
3.02
1.2
1.5
—
—
—
0
0
101
773
1.69
3.02
6.0
6.3
8.26
8.58
%
0.69
94
724
42
250
1.89
3.01
2.1
2.2
2.38
2.33
g/l
0.24
36
235
100
766
1.68
2.96
6.0
6.2
0.62
0.71
%
1.12
93
713
148
1268
1.92
2.91
7.0
4.4
14.46
14.75
pmol/l
0.73
140
1162
100
770
1.67
2.87
5.9
6.2
2.54
2.82
%
0.71
93
721
60
404
1.73
2.85
1.5
1.3
0.52
1.31
u/ml
1.17
19
108
43
649
0.56
2.83
3.1
3.1
—
—
—
0
0
106
833
1.66
2.78
6.1
6.3
0.58
0.56
e9/l
0.57
93
715
6
10
6.16
2.72
1.7
1.9
100.67
72.60
umol/l
—
6
10
47
299
1.77
2.71
6.0
3.3
13.50
269.33
ng/l
1.49
34
226
109
867
1.65
2.69
6.2
6.5
0.17
0.18
e9/l
0.48
92
753
106
839
1.64
2.65
6.2
6.3
0.04
0.04
e9/l
0.54
93
716
107
853
1.62
2.57
6.3
6.2
1.99
1.98
e9/l
0.03
96
751
14
57
2.58
2.51
2.9
3.3
—
—
—
0
0
76
564
1.60
2.42
2.5
3.3
2.36
2.36
mmol/l
0.06
71
519
26
143
1.96
2.34
4.3
4.3
7.37
7.34
ph
0.76
19
94
26
144
1.94
2.29
1.1
1.2
—
—
—
0
0
6
161
0.35
2.15
1.0
1.3
—
—
—
0
0
35
218
1.75
2.15
3.0
2.5
88.48
134.89
ug/g
0.77
25
169
35
219
1.74
2.11
1.7
1.4
—
—
—
0
0
9
31
3.00
2.10
1.8
2.5
8.06
7.88
kpa
—
9
31
10
38
2.72
2.04
1.3
1.2
—
—
—
0
0
17
84
2.13
2.03
3.2
3.4
24.00
24.66
mmol/l
0.34
17
84
6
16
3.84
1.95
2.3
3.6
—
—
—
0
0
108
900
1.50
1.87
7.0
3.8
0.00
0.00
estimate
-0.00
29
179
32
203
1.70
1.84
2.1
1.5
—
—
—
0
0
23
132
1.85
1.84
2.7
3.4
65.20
73.31
e9/l
0.59
17
93
98
806
1.47
1.78
3.4
2.9
95.53
95.62
ug/l
0.00
87
764
26
157
1.77
1.78
3.6
2.0
0.00
0.00
estimate
—
6
32
17
90
1.98
1.72
4.5
2.4
0.70
0.62
%
0.67
17
90
108
910
1.46
1.71
7.5
3.9
0.00
0.00
estimate
-0.00
27
164
29
185
1.68
1.64
1.6
1.7
—
—
—
0
0
106
895
1.44
1.62
7.2
3.8
0.00
0.00
estimate
-0.00
27
173
5
14
3.64
1.62
1.8
2.2
92.78
89.15
%
—
5
14
17
92
1.94
1.62
4.5
2.4
1.54
1.35
%
0.25
17
92
7
26
2.76
1.59
1.0
1.0
—
—
—
0
0
22
131
1.77
1.58
2.1
3.3
59.31
69.31
ng/l
0.50
17
114
161
1486
1.76
1.58
8.9
5.4
1.65
1.87
mu/l
2.16
150
1378
83
674
1.43
1.55
7.3
3.6
0.08
0.00
estimate
0.48
24
143
13
65
2.08
1.53
1.1
1.3
—
1.86
—
0
5
50
371
1.48
1.49
1.5
1.5
1.98
2.32
g/l
1.25
31
225
11
52
2.19
1.47
2.9
1.8
—
—
—
0
0
10
46
2.24
1.42
1.1
1.2
—
—
—
0
0
45
330
1.48
1.42
2.2
1.9
—
—
—
0
0
87
724
1.39
1.37
11.6
11.3
0.00
0.00
e9/l
0.38
73
592
34
237
1.54
1.36
2.1
2.0
—
—
—
0
0
8
159
0.48
1.32
1.4
1.5
—
—
—
0
0
55
426
1.42
1.30
2.2
2.7
330.43
331.70
umol/l
0.03
49
378
11
56
2.03
1.25
2.5
2.2
—
—
—
0
0
22
141
1.64
1.24
2.6
5.0
1.78
0.56
%
—
9
39
28
191
1.55
1.23
1.8
2.9
4.00
5.63
umol/l
1.34
21
170
64
516
1.37
1.19
4.6
4.1
23.74
10.00
mg/mmol
0.49
39
323
23
151
1.60
1.19
2.7
4.9
0.50
1.00
%
—
8
47
26
176
1.56
1.18
1.9
3.2
1.86
1.86
%
0.01
21
163
166
1568
1.71
1.17
26.1
14.9
21.40
21.76
mg/l
0.06
151
1273
67
548
1.35
1.13
2.0
2.2
—
—
—
0
0
61
492
1.36
1.12
9.1
6.7
—
—
—
0
0
160
1503
1.56
1.09
8.5
6.1
39.59
38.89
mmol/mol
0.33
145
1422
12
201
0.57
1.08
1.1
1.2
—
—
—
0
0
15
91
1.71
1.04
1.2
1.2
—
—
—
0
0
5
22
2.31
1.04
1.4
1.5
—
—
—
0
0
5
22
2.31
1.04
1.4
1.5
—
—
—
0
0
5
22
2.31
1.04
1.4
1.5
—
—
—
0
0
5
22
2.31
1.04
1.4
1.5
—
—
—
0
0
21
140
1.57
1.03
2.8
5.1
0.00
0.17
%
—
6
36
91
790
1.31
0.99
2.8
2.6
—
—
estimate
—
0
0
28
203
1.45
0.94
2.3
3.0
4.65
4.30
e9/l
0.22
21
177
6
27
2.26
0.94
5.5
3.8
4.37
4.54
e9/l
—
6
27
6
28
2.18
0.92
3.2
2.3
8.65
8.59
kpa
—
6
28
6
28
2.18
0.92
3.2
2.3
5.92
5.31
kpa
—
6
28
21
144
1.52
0.92
2.7
5.3
0.00
0.05
%
—
6
37
8
42
1.95
0.90
2.8
2.5
7.40
7.42
ph
—
8
42
18
121
1.54
0.86
5.3
3.9
—
—
—
0
0
11
65
1.74
0.84
1.5
1.3
—
—
—
0
0
12
184
0.63
0.79
1.8
1.7
—
—
—
0
0
60
508
1.27
0.76
4.0
3.4
75.29
56.76
mg/l
0.23
38
330
14
92
1.57
0.75
4.8
7.2
26.70
25.23
mmol/l
0.31
14
92
7
39
1.83
0.73
1.1
1.3
—
—
—
0
0
5
26
1.95
0.71
1.0
1.0
—
—
—
0
0
7
43
1.65
0.67
1.1
1.2
—
—
—
0
0
7
44
1.61
0.66
1.1
1.2
3.84
3.74
mmol/l
—
7
39
5
29
1.74
0.64
2.6
2.3
—
—
—
0
0
32
255
1.31
0.64
4.0
3.0
3.17
3.39
e6/l
0.06
20
117
42
499
0.79
0.62
1.6
1.4
—
—
—
0
0
11
72
1.56
0.60
1.3
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.6
—
—
—
0
0
47
399
1.24
0.58
6.2
5.6
—
—
—
0
0
6
40
1.52
0.52
5.3
3.5
57.00
62.02
%
—
6
40
60
672
0.84
0.48
1.9
2.1
—
—
—
0
0
7
48
1.48
0.47
1.0
1.3
—
—
—
0
0
16
207
0.75
0.45
1.1
1.4
—
—
—
0
0
10
69
1.48
0.45
1.8
1.8
7.26
5.93
ug/l
—
10
60
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.2
—
10.73
—
0
16
37
321
1.19
0.37
1.1
1.3
1.46
10.09
u/ml
3.04
17
129
7
53
1.33
0.31
13.1
11.1
—
—
—
0
0
154
1575
0.85
0.27
5.4
4.9
1.41
1.51
mmol/l
2.31
137
1470
33
294
1.15
0.25
2.0
1.6
—
—
—
0
0
21
180
1.19
0.25
2.0
1.8
—
—
—
0
0
25
220
1.16
0.22
1.6
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
164.89
—
0
11
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.6
—
0.85
—
0
13
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
10
82
1.23
0.17
2.9
1.9
—
—
—
0
0
13
111
1.18
0.16
1.5
2.4
—
—
—
0
0
157
1546
1.12
0.15
6.5
4.9
6.07
5.88
mmol/l
0.86
141
1427
169
1673
1.15
0.12
33.1
18.9
75.80
73.32
umol/l
0.35
169
1653
12
137
0.87
0.12
1.8
1.5
—
—
—
0
0
5
44
1.14
0.10
6.4
4.5
—
—
—
0
0
6
55
1.09
0.09
1.8
3.4
58.53
29.30
mg/l
—
6
49
6
55
1.09
0.09
1.8
3.4
45.62
38.21
mg/l
—
6
49
6
71
0.84
0.08
1.8
2.3
—
—
—
0
0
159
1604
0.93
0.07
6.3
5.7
2.73
2.74
mmol/l
0.04
142
1496
151
1495
1.06
0.07
4.4
4.2
1.49
1.26
mmol/l
2.92
130
1389
50
486
1.04
0.05
6.6
3.3
0.00
0.00
estimate
-0.00
24
136
163
1639
0.94
0.03
25.5
12.8
—
—
—
0
0
12
112
1.08
0.03
1.3
1.3
—
—
—
0
0
167
1664
1.05
0.00
15.8
12.0
25.18
25.47
u/l
0.10
158
1626
15
151
0.99
0.00
1.4
1.4
—
—
—
0
0
35
345
1.02
0.00
1.2
1.3
11.88
31.21
iu/ml
2.41
11
108
70
703
0.99
0.00
2.0
1.9
1.52
1.32
mmol/l
0.91
56
603
0
5
0.00
0.00
0.0
21.4
—
5.78
—
0
5
0
5
0.00
0.00
0.0
1.8
—
202.94
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
5
55
0.91
0.00
1.4
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
0.00
—
0
8
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
158
1580
1.00
-0.00
5.4
5.0
4.57
4.70
mmol/l
0.82
141
1480
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
99.40
—
0
9
0
7
0.00
-0.00
0.0
1.7
—
68.14
—
0
7
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
37.7
—
78.17
—
0
6

Mortality – FinRegistry

↥

Association

Association between endpoint F5_HISPER and mortality.

Females

Parameter HR [95% CI] p-value
F5_HISPER 3.111 [2.32, 4.18] < 0.001
Birth year 0.994 [0.99, 1.0] 0.171

During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 395 females with F5_HISPER died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_HISPER.

N-year risk Females Males
1 0.352% No data
5 1.577% No data
10 4.391% No data
15 7.889% No data
20 13.936% No data

Relationships between endpoints

↥

Index endpoint: F5_HISPER – Histrionic personality disorder

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data