No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
7819 |
4. Check minimum number of eventsNone |
7819 |
5. Include endpointsNone |
7819 |
6. Filter based on genotype QC (FinnGen only) |
7127 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H33
- Name in latin
- Ruptura retinae sine ablatione
Similar endpoints
↥List of similar endpoints to
Retinal breaks without detachment
based on the number of shared cases.
Similar with more cases:
- Retinal detachments and breaks
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 37057 | 20151 | 16809 |
| Only index persons | 36278 | 19857 | 16421 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.53 | 0.58 | 0.47 |
| Only index persons | 0.68 | 0.73 | 0.63 |
| Median age at first event (years) | |||
| Whole population | 60.88 | 60.16 | 61.81 |
| Only index persons | 60.82 | 60.09 | 61.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7127 | 4014 | 3113 |
| Unadjusted period prevalence (%) | 1.43 | 1.43 | 1.43 |
| Median age at first event (years) | 61.49 | 59.88 | 63.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 7345
- Matched controls
- 73450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
44.3
320.4
190
44
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
66.4
307.7
219
34
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
55.3
307.7
323
61
H33.5
ICD-10 Finland
Other retinal detachments
34.5
307.7
260
78
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
65.8
307.7
186
29
H35.4
ICD-10 Finland
Peripheral retinal degeneration
230.4
307.7
309
14
H43.8
ICD-10 Finland
Other disorders of vitreous body
7.3
307.7
2233
4169
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2125.7
307.7
1341
8
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.3
307.7
916
2343
WX140
NOMESCO Finland
Parabulbar anesthesy
17.0
307.7
885
588
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
191.3
307.7
329
18
H33.3
ICD-10 Finland
Retinal breaks without detachment
692942.5
307.7
7314
25
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
65.9
307.7
279
44
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.3
307.7
1140
3003
H43.1
ICD-10 Finland
Vitreous haemorrhage
30.6
307.7
829
304
CKC12
NOMESCO Finland
Photocoagulation of retina
1339.6
307.7
4382
81
CKC10
NOMESCO Finland
Local photocoagulation of retina
554.7
307.7
792
16
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.5
307.7
1381
4525
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
49.7
307.7
391
83
CKD40
NOMESCO Finland
Endophotocoagulation of retina
537.5
307.7
408
8
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
267.3
307.7
428
17
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
50.6
307.7
518
110
H26.4
ICD-10 Finland
After-cataract
3.5
263.5
1025
3254
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
10.2
237.3
271
276
H33
ICD-10 Finland
Retinal detachments and breaks
55.6
231.8
131
24
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.6
223.2
824
2517
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.2
216.5
2759
15711
H34.8
ICD-10 Finland
Other retinal vascular occlusions
61.0
215.9
120
20
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
213.2
2563
14238
H52.1
ICD-10 Finland
Myopia
5.0
197.0
437
911
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.1
193.4
563
1455
CKC15
NOMESCO Finland
Panretinal photocoagulation
101.4
193.2
100
10
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
188.3
180
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
187.6
1561
7359
S01ED51
ATC
timolol, combinations; ophthalmic
3.2
171.4
728
2414
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
167.6
3579
23997
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
338.7
165.8
167
5
XCH00
NOMESCO Finland
Eye pressure measurement
3.9
164.5
510
1376
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
157.9
151
*
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
154.0
741
2637
H43.9
ICD-10 Finland
Disorder of vitreous body, unspecified
7.7
140.7
199
265
H26.2
ICD-10 Finland
Complicated cataract
8.7
135.5
172
201
H35.37
ICD-10 Finland
Macular holes
230.9
132.4
136
6
H25.1
ICD-10 Finland
Senile nuclear cataract
1.9
129.0
2032
12050
CKD20
NOMESCO Finland
Removal of vitreous body substitute
634.1
126.8
125
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
315.5
121.6
123
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.5
120.3
429
1269
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
383.4
113.8
114
*
S01EA03
ATC
apraclonidine; ophthalmic
10.0
104.1
119
121
CKD15
NOMESCO Finland
Injection of vitreous substitute
992.1
100.4
98
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
97.1
93
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
250.9
96.9
99
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
93.6
1022
5256
WX142
NOMESCO Finland
Sub-tenon anesthesy
13.2
90.4
86
66
XCD20
NOMESCO Finland
Photoangiography of eye
15.1
85.3
75
50
Z2221
NOMESCO Finland
Medical doctor
1.7
83.8
2002
13174
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
14.6
82.7
74
51
XCK10
NOMESCO Finland
Photography of fundus of eye
2.3
79.1
632
2857
S01ED01
ATC
timolol; ophthalmic
3.3
70.0
266
817
H26.02
ICD-10 Finland
Presenil cataract
3.3
69.4
270
841
H35.7
ICD-10 Finland
Separation of retinal layers
232.1
67.3
69
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
8.3
67.1
88
107
H43.3
ICD-10 Finland
Other vitreous opacities
4.1
64.5
177
435
WX002
NOMESCO Finland
Sedation and analgesia
1.7
61.2
1414
9112
ZXA05
NOMESCO Finland
Left side
1.6
60.7
1741
11844
F29
ICPC
Eye symptom/complaint other
1.9
60.4
831
4593
H25.8
ICD-10 Finland
Other senile cataract
1.9
59.6
771
4175
H43
ICD-10 Finland
Disorders of vitreous body
6.3
59.3
100
161
S01EC01
ATC
acetazolamide; systemic
4.0
58.3
165
415
ZXA00
NOMESCO Finland
Right side
1.6
57.3
1876
13140
H35.36
ICD-10 Finland
Macular cyst
198.2
57.1
59
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
24.5
54.9
39
16
H35.6
ICD-10 Finland
Retinal haemorrhage
97.5
52.9
58
6
S01EE01
ATC
latanoprost; ophthalmic
2.2
51.8
440
2033
ZXA10
NOMESCO Finland
Bilateral
1.7
51.2
1207
7779
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
49.0
898
5401
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
49.0
47
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.5
48.2
300
1207
S01EA05
ATC
brimonidine; ophthalmic
3.3
46.8
179
552
H20.1
ICD-10 Finland
Chronic iridocyclitis
5.3
45.6
92
176
H25.0
ICD-10 Finland
Senile incipient cataract
2.0
44.8
498
2549
114
Kela drug reimbursment
Glaucoma
1.9
44.6
567
3042
A98
ICPC
Health maint/preventive medicine
2.6
44.5
7134
68130
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.5
44.2
157
462
F05
ICPC
Visual disturbance other
2.6
43.4
266
1062
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
42.7
41
*
S01EC04
ATC
brinzolamide; ophthalmic
2.5
41.4
274
1135
S01BC05
ATC
ketorolac; ophthalmic
2.7
41.4
224
841
H33.4
ICD-10 Finland
Traction detachment of retina
140.8
39.8
42
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
7.1
39.3
59
84
H44.2
ICD-10 Finland
Degenerative myopia
14.6
39.1
35
24
H3601, E113,
ICD-10 Finland
+∞
38.6
37
*
H33.2
ICD-10 Finland
Serous retinal detachment
68.6
36.0
41
6
H3600, E113,
ICD-10 Finland
+∞
35.4
34
*
3613A
ICD-9 Finland
Retinal detachments and defects, Retinal defects without detachment
+∞
35.4
34
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
7.4
33.5
48
65
H3603, E103,
ICD-10 Finland
+∞
33.4
32
*
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
33.4
32
*
H3603, E113,
ICD-10 Finland
+∞
33.4
32
*
F04
ICPC
Visual floaters/spots
5.1
33.1
69
136
H40.0
ICD-10 Finland
Glaucoma suspect
1.8
32.9
565
3320
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
117.2
32.7
35
*
H3600, E103,
ICD-10 Finland
+∞
32.3
31
*
H53
ICD-10 Finland
Visual disturbances
4.2
32.1
85
204
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
37.2
29.3
37
10
H53.8
ICD-10 Finland
Other visual disturbances
3.1
28.7
118
381
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
150.6
28.6
30
*
H57.1
ICD-10 Finland
Ocular pain
2.2
28.4
256
1211
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.9
28.3
83
215
H27.1
ICD-10 Finland
Dislocation of lens
7.7
28.0
39
51
H30.2
ICD-10 Finland
Posterior cyclitis
282.6
27.8
28
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
42.7
27.7
34
8
R01AD09
ATC
mometasone; nasal
1.3
27.6
2981
25083
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
27.2
1233
9041
XCK00
NOMESCO Finland
Perimetry
1.9
26.4
366
2015
CS494
NOMESCO Finland
Other visual field testing
2.4
25.9
175
733
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.5
25.4
87
251
H3601, E103,
ICD-10 Finland
+∞
25.0
24
*
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
251.1
24.7
25
*
ZXE00
NOMESCO Finland
One hour or less
1.3
24.1
2420
20051
H36.00
ICD-10 Finland
Diabetic background retinopathy
8.6
23.6
30
35
H35.8
ICD-10 Finland
Other specified retinal disorders
23.7
23.4
33
14
H36.01
ICD-10 Finland
Diabetic maculopathy
28.3
23.1
31
11
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
22.1
23.0
33
15
S01EE05
ATC
tafluprost; ophthalmic
2.0
22.9
237
1181
H35.9
ICD-10 Finland
Retinal disorder, unspecified
19.0
22.5
34
18
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
1.9
21.9
276
1473
H34.2
ICD-10 Finland
Other retinal artery occlusions
62.7
21.8
25
*
R01AD08
ATC
fluticasone; nasal
1.3
21.7
1810
14572
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.6
21.4
498
3166
S01BC03
ATC
diclofenac; ophthalmic
2.5
21.4
130
519
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
6.4
20.9
34
53
H34.1
ICD-10 Finland
Central retinal artery occlusion
77.0
20.7
23
*
3745
FHL
Hard membrane girding, cerclage with coagulation
73.7
19.7
22
*
XCW10
NOMESCO Finland
Assessment of vision
2.9
19.5
92
323
Z71.8
ICD-10 Finland
Other specified counselling
1.3
19.4
2150
17927
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
19.1
1395
10992
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
19.1
2283
19208
F43
ICPC
Eye, Other diagnostic procedure
2.3
19.0
147
654
H21.0
ICD-10 Finland
Hyphaema
5.9
18.7
33
56
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
5.6
18.6
35
63
J01FA10
ATC
azithromycin; systemic
1.2
18.5
3674
32721
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
5.5
18.3
35
64
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
18.3
1319
10366
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
18.2
1918
15864
A02BC05
ATC
esomeprazole; systemic
1.3
18.2
2740
23653
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.0
18.0
208
1079
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
26.7
17.8
24
9
CKD25
NOMESCO Finland
External drainage of subretinal fluid
+∞
17.7
17
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
2.8
17.5
85
303
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
17.2
1876
15560
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
17.1
1711
14039
A10AA01, ,
ATC
3.0
16.6
73
247
G47.3
ICD-10 Finland
Sleep apnoea
1.3
16.5
1574
12827
R01AD12
ATC
fluticasone furoate; nasal
1.3
16.4
1884
15713
M79.6
ICD-10 Finland
Pain in limb
1.2
16.2
2921
25614
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
15.9
2382
20461
H31.0
ICD-10 Finland
Chorioretinal scars
60.1
15.7
18
*
1LA05, ,
NOMESCO Finland
+∞
15.6
15
*
CKC75
NOMESCO Finland
Removal of cerclage from sclera
+∞
15.6
15
*
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.5
15.6
520
3579
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
15.4
805
6010
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
15.4
1453
11814
A02BC02
ATC
pantoprazole; systemic
1.2
15.2
4769
44139
F38
ICPC
Eye, Other laboratory test NEC
2.3
15.1
109
472
G04CA01
ATC
alfuzosin; oral
1.4
15.0
771
5741
Z3231
NOMESCO Finland
Registered nurse
1.3
15.0
1630
13482
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
1.8
14.9
207
1142
S01EE03
ATC
bimatoprost; ophthalmic
2.2
14.8
126
586
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
14.4
3018
26769
S01KA02
ATC
hypromellose; ophthalmic
2.3
14.3
108
477
ZXD20
NOMESCO Finland
Day surgery
1.4
14.3
751
5608
DFF00
NOMESCO Finland
Pure tone audiometry
1.4
14.2
660
4829
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
14.2
2872
25376
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
2.4
14.2
96
405
H26.9
ICD-10 Finland
Cataract, unspecified
2.2
14.0
113
514
J01CA04
ATC
amoxicillin; systemic
1.2
13.9
5454
51370
R5140
NOMESCO Finland
Monitoring the use of the aid
1.4
13.9
719
5358
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
5.5
13.8
26
47
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
2.1
13.8
130
629
M03BX02
ATC
tizanidine; oral
1.2
13.7
4169
38252
J02AC01
ATC
fluconazole; systemic
1.2
13.6
2399
20877
A10AA02, ,
ATC
2.5
13.5
85
347
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
34.1
13.5
17
5
M01AH05
ATC
etoricoxib; oral
1.2
13.5
4293
39531
R42
ICD-10 Finland
Dizziness and giddiness
1.3
13.0
1403
11565
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
4.1
13.0
35
86
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
13.0
1925
16443
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
2.9
13.0
59
204
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
12.9
801
6137
A10AB01
ATC
insulin (human); parenteral
2.3
12.9
97
429
J01DB01
ATC
cefalexin; oral
1.2
12.9
5647
53520
S01EE04
ATC
travoprost; ophthalmic
2.2
12.8
106
488
Z01.2
ICD-10 Finland
Dental examination
1.2
12.7
2942
26241
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
12.7
1306
10705
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
3.0
12.6
53
175
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
12.5
3324
30008
CKD30
NOMESCO Finland
Internal drainage of subretinal fluid
+∞
12.5
12
*
S01FA04
ATC
cyclopentolate; ophthalmic
2.6
12.4
70
271
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
130.2
12.4
13
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
13.2
12.4
21
16
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
12.3
1389
11505
H04AA01
ATC
glucagon; nasal, parenteral
2.8
12.3
60
216
S29
ICPC
Skin symptom/complaint other
1.3
12.2
1292
10619
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.4
12.2
636
4744
A97
ICPC
No disease
1.3
11.9
1210
9899
U07.2
ICD-10 Finland
COVID-19, virus not identified
1.3
11.8
908
7166
M01AE02
ATC
naproxen; oral, rectal
1.2
11.8
3580
32632
EB1SA, ,
SPAT
1.6
11.8
280
1790
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
11.8
432
3029
Z01.7
ICD-10 Finland
Laboratory examination
1.3
11.5
1012
8130
J01AA02
ATC
doxycycline; systemic
1.2
11.5
5354
50649
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
120.2
11.4
12
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
120.2
11.4
12
*
H53.4
ICD-10 Finland
Visual field defects
2.0
11.4
113
559
J01FA09
ATC
clarithromycin; systemic
1.2
11.4
1915
16531
R01AD01
ATC
beclometasone; nasal
1.3
11.4
891
7051
S01BA07
ATC
fluorometholone; ophthalmic
2.2
11.3
92
422
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
5.1
11.2
23
45
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.6
11.2
65
256
J31.0
ICD-10 Finland
Chronic rhinitis
1.4
11.1
497
3614
A10BA02
ATC
metformin; oral
0.8
11.1
1283
15316
N02BE01
ATC
paracetamol; systemic, rectal
1.3
11.0
6285
60533
S82
ICPC
Naevus/mole
1.3
10.9
845
6672
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.5
10.8
332
2251
M01AB05
ATC
diclofenac; systemic, rectal
1.2
10.8
4439
41390
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
10.7
2161
18957
WX320
NOMESCO Finland
Spinalanesthesy
1.2
10.6
1544
13122
H43.0
ICD-10 Finland
Vitreous prolapse
5.3
10.6
21
40
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.3
10.6
753
5881
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
2.6
10.6
61
240
R05
ICD-10 Finland
Cough
1.2
10.5
1326
11104
H3602, E103,
ICD-10 Finland
+∞
10.4
10
*
CKD75
NOMESCO Finland
Retinotomy
+∞
10.4
10
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.2
10.3
1195
9906
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
10.3
4717
44276
C05AA08
ATC
fluocortolone; rectal, topical
1.3
10.3
816
6466
G04CA02
ATC
tamsulosin; oral
1.2
10.2
1400
11817
L03
ICPC
Low back symptom/complaint
1.2
10.2
1781
15402
R06AX27
ATC
desloratadine; oral
1.2
10.0
1637
14065
GD1AA, ,
SPAT
1.3
10.0
900
7247
F82
ICPC
Detached retina
40.1
10.0
12
*
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.5
9.9
265
1743
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
9.9
1555
13307
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.2
9.9
1791
15537
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
9.8
3148
28658
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
1.5
9.8
282
1884
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
9.8
2176
19223
H02
ICPC
Hearing complaint
1.3
9.7
909
7351
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
9.7
1897
16565
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
2.4
9.7
66
281
K07.60
ICD-10 Finland
Snapping jaw
1.5
9.6
259
1708
G04BD12
ATC
mirabegron; oral
1.3
9.6
745
5887
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
9.5
2826
25552
M25.5
ICD-10 Finland
Pain in joint
1.2
9.5
2084
18376
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
100.2
9.4
10
*
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
9.4
2424
21662
3759
FHL
Other measure in this category
+∞
9.4
9
*
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
+∞
9.4
9
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
9.4
9
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
9.4
9
*
A06AC51
ATC
ispaghula, combinations; oral
1.5
9.4
268
1791
S01BA01
ATC
dexamethasone; ophthalmic
1.6
9.3
185
1135
D07AC13
ATC
mometasone; topical
1.2
9.3
1731
15040
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.2
9.3
1049
8669
F28
ICPC
Limited function/disability (F)
2.9
9.2
42
146
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.3
9.2
817
6567
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
4.1
9.2
24
58
CK2X4, ,
SPAT
4.3
9.1
23
54
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.4
9.1
433
3183
L15
ICPC
Knee symptom/complaint
1.2
9.1
1603
13855
D19
ICPC
Teeth/gum symptom/complaint
1.2
9.0
1860
16299
A02BC04
ATC
rabeprazole; oral
1.3
8.9
508
3841
F13
ICPC
Eye sensation abnormal
1.7
8.7
160
963
A10AB04
ATC
insulin lispro; parenteral
2.0
8.7
95
488
N05CF02
ATC
zolpidem; oral
1.2
8.7
1013
8395
F01
ICPC
Eye pain
1.7
8.7
158
948
H93.1
ICD-10 Finland
Tinnitus
1.4
8.7
422
3113
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
2.0
8.7
92
468
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.5
8.6
221
1442
H40.9
ICD-10 Finland
Glaucoma, unspecified
2.0
8.6
89
449
S21
ICPC
Skin texture symptom/complaint
1.2
8.6
919
7545
J05AB11
ATC
valaciclovir; oral
1.3
8.6
854
6955
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.4
8.5
391
2859
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
6.4
8.5
21
33
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
90.2
8.4
9
*
H01.0
ICD-10 Finland
Blepharitis
1.4
8.4
360
2600
J01MA02
ATC
ciprofloxacin; systemic
1.2
8.4
2409
21664
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
1.4
8.4
380
2773
L12
ICPC
Hand/finger symptom/complaint
1.2
8.4
1001
8320
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
8.3
8
*
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
8.3
8
*
3742
FHL
Cryocoagulation under general anesthesia
+∞
8.3
8
*
H3602, E113,
ICD-10 Finland
+∞
8.3
8
*
M01AX05
ATC
glucosamine; oral
1.2
8.3
1167
9861
L57.0
ICD-10 Finland
Actinic keratosis
1.3
8.3
628
4944
H20.8
ICD-10 Finland
Other iridocyclitis
3.2
8.2
31
97
R01AD58
ATC
fluticasone, combinations; nasal
1.2
8.1
1386
11925
D22
ICD-10 Finland
Melanocytic naevi
1.5
8.1
274
1894
C09CA06
ATC
candesartan; oral
1.2
8.1
1508
13079
H26.8
ICD-10 Finland
Other specified cataract
2.4
8.1
54
229
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
3.2
8.0
30
93
R74
ICPC
Upper respiratory infection acute
1.2
8.0
1750
15383
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.2
8.0
1636
14303
G04CB01
ATC
finasteride; oral
1.3
8.0
571
4459
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
0.8
8.0
1081
12752
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.7
8.0
291
4077
L17
ICPC
Foot/toe symptom/complaint
1.2
7.9
1914
16966
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
7.9
1731
15223
S01AA01
ATC
chloramphenicol; ophthalmic
1.5
7.9
247
1684
H35
ICD-10 Finland
Other retinal disorders
13.0
7.9
13
10
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
1.9
7.8
93
493
ZX198
NOMESCO Finland
Other local administration
2.9
7.8
34
116
R06AE07
ATC
cetirizine; oral
1.2
7.7
2636
23978
S01FA01
ATC
atropine; ophthalmic
4.2
7.7
20
48
CA1ME
NOMESCO Finland
Ultrasound oculometry
3.0
7.7
32
106
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
3.0
7.7
32
106
R35
ICD-10 Finland
Polyuria
1.4
7.6
393
2927
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.6
7.6
174
2667
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
0.6
7.6
171
2630
N17
ICPC
Vertigo/dizziness
1.3
7.6
718
5812
HA1AE, ,
SPAT
1.6
7.6
160
1000
R03BA02
ATC
budesonide; inhalant
1.2
7.5
998
8382
CS2P4
NOMESCO Finland
Optic nerve head imaging
2.4
7.5
50
212
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.3
7.5
567
4466
D06BB10
ATC
imiquimod; topical
1.4
7.5
273
1919
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
2.3
7.4
52
225
S18
ICPC
Laceration/cut
1.1
7.4
3098
28559
UJF30
NOMESCO Finland
Ileoscopy through colon
1.3
7.4
620
4945
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
3.1
7.4
29
93
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
2.5
7.4
44
177
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
7.3
7
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
7.3
7
*
N02CC04
ATC
rizatriptan; oral
1.4
7.3
269
1895
XKD00
NOMESCO Finland
Uroflowmetry
1.2
7.3
904
7540
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.7
7.3
124
734
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.0
7.2
73
366
H02AB04
ATC
methylprednisolone; systemic
1.2
7.2
813
6708
R49.03
ICD-10 Finland
Atrophic dysphonia
2.0
7.2
69
339
H40.8
ICD-10 Finland
Other glaucoma
3.3
7.2
26
79
D01AE16
ATC
amorolfine; topical
1.3
7.2
659
5314
SDA03
NOMESCO Finland
Periodontal treatment
1.2
7.2
2516
22900
D07AD01
ATC
clobetasol; topical
1.2
7.2
1023
8649
G45.3
ICD-10 Finland
Amaurosis fugax
1.8
7.1
101
568
SFA20
NOMESCO Finland
Two-surface restoration
1.1
7.1
3713
34722
M79.1
ICD-10 Finland
Myalgia
1.2
7.1
828
6863
CFB00
NOMESCO Finland
Suture of conjunctiva
6.0
7.1
18
30
R03BA05
ATC
fluticasone; inhalant
1.2
7.0
992
8379
C07AA05
ATC
propranolol; systemic
1.2
7.0
1099
9374
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.2
7.0
942
7919
H29
ICPC
Ear symptom/complaint other
1.3
7.0
707
5767
N02AJ06
ATC
codeine and paracetamol; systemic
1.1
7.0
2726
24989
E0000UV, ,
ATC
1.1
6.9
2489
22677
H02AB07
ATC
prednisone; oral
1.2
6.9
757
6227
Z01.9
ICD-10 Finland
Special examination, unspecified
1.4
6.9
335
2473
J05AB01
ATC
aciclovir; systemic
1.2
6.9
1257
10867
R06.0
ICD-10 Finland
Dyspnoea
1.2
6.9
1611
14218
R03AC02
ATC
salbutamol; inhalant
1.1
6.9
3411
31752
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
6.9
6213
60317
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.4
6.8
357
2667
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.1
6.8
2750
25248
R4110
NOMESCO Finland
Physiotherapy
1.2
6.8
1706
15147
R00.2
ICD-10 Finland
Palpitations
1.3
6.8
427
3282
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.3
6.7
605
4867
J01FA06
ATC
roxithromycin; oral
1.1
6.7
2398
21830
D07AC01
ATC
betamethasone; topical
1.1
6.7
2245
20347
H40
ICD-10 Finland
Glaucoma
2.2
6.7
52
236
R06AE09
ATC
levocetirizine; oral
1.2
6.7
751
6195
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
22.5
6.7
9
*
R83
ICPC
Respiratory infection other
1.2
6.7
1281
11125
Z94.0
ICD-10 Finland
Kidney transplant status
2.2
6.6
52
238
130
Kela drug reimbursment
Malignant tumour
0.7
6.6
322
4298
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
3.3
6.5
23
69
T89
ICPC
Diabetes insulin dependent
1.6
6.5
131
810
M02AA07
ATC
piroxicam; topical
1.1
6.5
2194
19883
D01
ICPC
Abdominal pain/cramps general
1.3
6.5
638
5185
R03DC03
ATC
montelukast; oral
1.2
6.5
923
7798
CKD60
NOMESCO Finland
Anterior vitrectomy
2.5
6.5
37
146
R03BC03
ATC
nedocromil; inhalant
1.3
6.5
365
2759
OAB43, ,
SPAT
1.2
6.5
1385
12131
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
1.5
6.4
184
1235
L04AD02
ATC
tacrolimus; systemic
2.2
6.4
51
234
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
2.5
6.4
38
153
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
6.4
611
4950
G47.8
ICD-10 Finland
Other sleep disorders
1.9
6.4
72
376
R05
ICPC
Cough
1.2
6.4
1470
12950
K02.0
ICD-10 Finland
Caries limited to enamel
1.2
6.4
1004
8566
C10AA07
ATC
rosuvastatin; oral
1.1
6.4
2286
20802
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.3
6.4
15
526
F99
ICPC
Eye/adnexa disease other
2.4
6.4
42
178
H02AB06
ATC
prednisolone; systemic
1.1
6.4
3018
27968
R51.80
ICD-10 Finland
Headache
1.2
6.3
802
6698
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.4
6.3
302
2225
H53.0
ICD-10 Finland
Amblyopia ex anopsia
2.4
6.3
39
160
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.3
6.3
21
616
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.2
6.3
651
5323
Q14.10
ICD-10 Finland
Congenital retinoschis
11.0
6.3
11
10
CKA10
NOMESCO Finland
Biopsy of vitreous body
9.2
6.3
12
13
H44.1
ICD-10 Finland
Other endophthalmitis
9.2
6.3
12
13
J35.0
ICD-10 Finland
Chronic tonsillitis
1.5
6.3
184
1242
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
6.2
6
*
L57
ICPC
Musculoskeletal, Physical medicine/rehabilitation
2.9
6.2
28
98
M54.5
ICD-10 Finland
Low back pain
1.1
6.2
2201
20009
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.4
6.1
282
2067
R4110, ,
SPAT
1.2
6.1
827
6956
N07BA03
ATC
varenicline; oral
0.6
6.1
114
1823
J02AC02
ATC
itraconazole; systemic
1.2
6.1
1033
8872
UKC02
NOMESCO Finland
Cystoscopy
1.2
6.1
903
7664
H81
ICPC
Excessive ear wax
1.2
6.0
1028
8829
KE1BG
NOMESCO Finland
MRI of prostate
2.0
6.0
62
314
R53
ICD-10 Finland
Malaise and fatigue
1.2
6.0
1337
11742
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
1.4
6.0
271
1980
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6820
64217
1.87
41.28
5.6
5.3
1.49
1.47
mmol/l
2.94
6319
59854
7211
69408
3.13
41.10
26.3
25.7
135.87
135.35
g/l
2.55
7155
68739
7210
69395
3.12
41.06
26.1
25.5
91.35
91.44
fl
1.04
7153
68716
7210
69400
3.12
40.96
26.2
25.5
4.50
4.48
e12/l
3.48
7066
67798
7210
69400
3.12
40.96
26.7
26.1
40.53
40.73
%
0.73
7151
68687
7208
69386
3.08
40.64
26.2
25.5
245.23
250.11
e9/l
8.99
7095
68025
7209
69407
3.09
40.51
26.2
25.6
6.51
6.68
e9/l
6.49
7074
67791
6918
65523
1.96
39.88
6.5
6.1
2.68
2.72
mmol/l
2.77
6434
61192
6700
62860
1.75
39.60
17.0
16.5
78.86
79.45
ml/min/173m2
2.01
6266
58512
6836
64570
1.85
38.70
5.7
5.4
4.62
4.66
mmol/l
2.61
6368
60567
5537
49893
1.45
38.58
4.8
4.5
11.14
12.44
mm/h
10.74
5165
46850
7096
67950
2.31
37.92
13.5
12.9
25.67
26.56
u/l
4.75
6884
66159
7123
68501
2.32
34.47
22.6
22.1
78.29
77.40
umol/l
1.59
7068
67782
6443
60262
1.56
33.53
5.9
5.4
1.89
1.93
mu/l
1.72
5954
55795
6540
61480
1.58
32.12
4.7
4.5
1.24
1.31
mmol/l
12.72
5995
56665
3538
30143
1.34
31.43
3.2
3.0
130.53
142.96
ug/l
2.01
3275
28137
6691
63359
1.63
30.47
5.6
5.4
5.88
5.95
mmol/l
5.99
6149
58528
6751
64088
1.66
30.20
16.8
16.8
23.17
24.91
mg/l
3.85
5442
53188
6952
66619
1.81
28.83
20.1
19.9
3.97
3.98
mmol/l
2.46
6823
65391
6940
66484
1.80
28.61
19.7
19.7
139.88
139.77
mmol/l
3.45
6825
65362
6575
62247
1.54
27.19
6.7
6.5
38.80
39.25
mmol/mol
4.71
6130
58354
4188
37077
1.30
25.89
2.8
2.7
—
—
—
0
0
3568
31009
1.29
25.02
2.5
2.4
80.88
78.45
nmol/l
5.51
3229
28134
5487
50765
1.32
22.46
4.7
4.4
14.76
14.81
pmol/l
1.01
5036
46814
3642
32052
1.27
21.83
6.7
6.6
57.06
57.26
%
0.49
3479
30593
1738
13908
1.33
21.77
3.6
3.3
0.75
0.77
ug/l
0.42
1199
9442
3694
32642
1.26
21.10
6.9
6.7
27.82
27.63
%
0.49
3497
30926
3382
29599
1.26
20.85
2.0
1.9
1.27
1.37
mmol/l
10.05
2786
24714
2273
18976
1.29
20.56
3.0
2.9
0.00
0.07
4.04
47
427
5641
52684
1.30
19.60
8.7
8.8
78.30
79.65
u/l
1.10
5349
50223
772
5546
1.44
18.59
2.3
2.3
13.52
13.32
nmol/l
0.28
710
4989
4782
43999
1.25
17.40
3.4
3.4
47.78
50.86
u/l
1.46
4467
41325
1085
8483
1.33
15.37
5.2
5.1
33.02
32.35
%
1.21
721
5628
3958
35978
1.22
14.92
6.8
6.7
0.19
0.19
e9/l
0.16
3420
31228
3907
35509
1.21
14.60
6.7
6.5
1.87
1.91
e9/l
0.53
3391
31019
3845
34921
1.21
14.37
6.7
6.4
0.04
0.04
e9/l
0.63
3275
29727
3833
34806
1.21
14.33
6.7
6.4
0.58
0.59
e9/l
1.88
3262
29622
650
4780
1.39
13.59
2.5
2.4
23.08
22.16
au/ml
0.09
70
492
3433
30959
1.20
13.44
2.2
2.1
99.21
95.77
pmol/l
3.63
1757
16349
1548
12926
1.25
12.85
1.5
1.5
2.42
2.50
g/l
0.49
909
7865
1454
12079
1.25
12.59
1.3
1.3
12.91
12.34
u/ml
0.11
519
4679
594
4398
1.38
11.90
1.3
1.3
41.77
54.40
au/ml
0.97
37
309
1540
12949
1.24
11.88
1.4
1.3
34.51
33.84
iu/ml
0.06
473
3990
2609
23144
1.20
11.65
6.4
5.7
2.96
2.95
ug/l
0.01
2374
21034
1716
14632
1.23
11.55
1.3
1.3
1.99
1.83
u/ml
0.11
392
3883
421
2990
1.43
10.74
2.2
1.9
39.79
39.14
u/l
0.27
384
2630
3846
35457
1.18
10.60
7.5
7.4
1.22
1.21
mmol/l
3.68
3330
30787
605
4642
1.33
9.62
1.9
1.8
3.38
3.49
mmol/l
1.59
442
3310
4195
39131
1.17
9.46
9.7
10.2
3.94
4.10
e9/l
4.74
3605
33761
1011
8303
1.25
9.46
2.1
2.4
106.38
138.28
ug/g
3.15
793
6636
2116
18694
1.19
9.41
4.8
4.6
21.81
21.99
%
0.22
1114
9573
2691
24333
1.17
8.88
3.5
3.7
2.36
2.36
mmol/l
0.07
2443
22111
279
1903
1.48
8.84
1.9
1.9
49.53
42.24
nmol/l
3.18
274
1836
1333
11351
1.21
8.80
3.5
3.2
2.21
2.44
e6/l
0.39
648
5490
1717
15006
1.19
8.51
1.8
1.8
1.05
1.30
mg/l
3.47
1315
11805
311
2184
1.44
8.49
2.0
1.7
4.17
4.36
mg/l
0.08
234
1645
303
2125
1.44
8.34
1.2
1.3
74.78
36.82
u/ml
0.96
11
109
2122
18911
1.17
8.28
2.8
2.8
340.95
342.74
umol/l
0.37
1849
16719
798
6474
1.26
8.26
2.2
2.1
3.32
3.46
ratio
2.47
633
5139
5554
53208
1.18
8.21
21.2
20.7
13.56
13.68
%
10.74
5493
52544
3444
31873
1.15
8.04
6.7
6.8
1.22
1.21
mmol/l
4.39
3146
29635
2030
18071
1.17
7.98
4.3
4.2
89.99
89.77
%
0.16
2005
17686
328
4499
0.72
7.91
6.7
7.2
24.48
24.60
mmol/l
0.25
308
4307
2214
19854
1.16
7.91
1.7
1.7
21.18
20.29
nmol/l
1.85
1830
16830
316
2260
1.42
7.83
1.6
1.7
—
—
—
0
0
222
1486
1.51
7.75
2.0
1.9
203.22
200.05
pmol/l
0.18
212
1408
281
1976
1.44
7.65
1.3
1.3
1.79
2.75
u/ml
1.66
16
175
281
1979
1.44
7.59
1.3
1.3
5.20
6.52
u/ml
0.24
37
285
449
3427
1.33
7.43
2.3
2.2
0.01
0.25
estimate
0.52
115
1069
4585
43459
1.15
7.19
4.9
4.7
1994.75
1214.49
e6/l
0.37
40
588
2426
22042
1.15
7.07
2.2
2.2
191.62
207.94
u/l
0.38
2301
20852
664
5370
1.26
7.06
4.1
3.7
83.58
89.84
ng/l
1.29
571
4661
3944
37040
1.14
7.00
6.5
7.1
11.40
11.58
umol/l
0.57
3739
35487
224
1552
1.46
6.65
1.2
1.3
36.76
45.79
u/ml
0.32
22
143
101
582
1.75
6.55
2.5
2.4
41.10
28.01
iu/ml
—
6
90
1584
14039
1.16
6.37
2.9
3.1
2.44
2.46
mmol/l
3.98
1421
12624
238
1687
1.42
6.28
1.2
1.3
2.06
3.91
u/ml
—
9
101
3228
30061
1.13
6.25
12.2
11.9
0.00
0.00
e9/l
0.32
2608
24366
155
2327
0.66
6.18
3.9
4.1
1.48
1.40
mmol/l
0.29
147
2289
1424
12558
1.17
6.09
3.4
3.0
1.26
1.33
e6/l
0.06
750
6715
1901
17131
1.15
6.04
2.6
2.4
—
—
—
0
0
522
4185
1.27
6.00
3.6
3.5
4.52
4.46
pmol/l
0.68
476
3750
2768
25587
1.13
5.94
4.6
4.0
52.13
94.99
e6/l
6.41
1884
18169
107
646
1.67
5.90
1.2
1.2
—
—
—
0
0
154
1019
1.52
5.79
1.1
1.2
11.50
6.67
u/ml
—
8
41
529
4270
1.26
5.75
1.3
1.3
205.49
233.76
u/ml
0.40
490
3958
98
584
1.69
5.69
1.1
1.2
—
—
—
0
0
1085
9410
1.18
5.69
1.5
1.5
—
—
—
0
0
810
6853
1.20
5.61
2.6
2.6
37.05
47.77
u/l
0.83
698
5811
91
535
1.71
5.56
1.1
1.2
—
—
—
0
0
3823
36129
1.12
5.51
4.1
3.9
0.01
0.07
estimate
0.74
739
6964
2045
18623
1.14
5.47
3.6
3.3
0.00
202.04
estimate
0.63
15
77
94
561
1.68
5.44
1.1
1.2
—
—
—
0
0
94
561
1.68
5.44
1.1
1.2
—
—
—
0
0
92
550
1.68
5.31
1.1
1.2
—
—
—
0
0
170
1171
1.46
5.29
1.3
1.2
241.48
285.62
u/ml
1.47
107
734
3369
31663
1.12
5.25
5.0
5.2
36.16
35.59
g/l
8.20
3133
29765
3787
35841
1.12
5.17
4.1
3.9
14.59
4.41
estimate
1.27
770
7394
4241
40400
1.12
5.14
5.1
5.2
6.62
6.68
mmol/l
1.03
4041
38562
391
3090
1.28
5.09
2.4
2.4
3.54
3.71
g/l
2.00
351
2837
1914
17425
1.13
5.08
2.4
2.3
2.62
2.82
mg/l
3.56
1623
15113
391
3092
1.28
5.07
2.4
2.4
4.24
4.22
g/l
0.10
351
2842
391
3095
1.28
5.03
2.4
2.4
7.11
7.38
g/l
2.14
351
2841
182
1283
1.43
5.03
1.8
1.9
5.17
5.05
mmol/24h
0.21
165
1142
3742
35428
1.11
5.01
4.1
3.9
0.00
0.00
estimate
2.09
754
7195
5515
53382
1.13
4.99
21.4
21.6
332.28
332.08
g/l
0.92
5502
53132
253
1892
1.35
4.92
2.4
1.9
11.51
11.99
mg/l
0.37
240
1756
2145
19710
1.12
4.85
3.7
3.3
0.33
0.41
e6/l
1.05
1530
14410
339
2654
1.29
4.77
2.4
2.4
10.17
10.14
g/l
0.05
297
2378
339
2662
1.29
4.67
2.2
2.0
—
—
—
0
0
1419
15744
0.88
4.60
4.1
4.1
1.02
1.11
kg/l
0.51
1015
10506
1225
10905
1.15
4.52
1.9
2.1
29.36
29.66
s
1.07
1196
10626
52
937
0.55
4.50
4.8
5.5
369.95
356.68
umol/l
0.34
40
817
367
2926
1.27
4.49
2.5
2.5
2.82
2.89
g/l
0.70
327
2675
382
3062
1.26
4.47
1.1
1.1
—
—
—
0
0
114
753
1.52
4.42
1.1
1.1
—
9.90
—
0
5
3376
31921
1.11
4.41
2.9
2.8
—
—
estimate
—
0
0
517
4300
1.22
4.31
1.8
1.7
—
—
—
0
0
259
1985
1.32
4.31
1.6
1.4
10.99
17.81
iu/ml
—
7
40
359
2871
1.26
4.29
1.6
1.7
6.04
6.71
iu/ml
0.29
84
654
66
384
1.73
4.28
2.2
1.9
—
—
—
0
0
66
384
1.73
4.28
2.2
1.9
—
—
—
0
0
66
384
1.73
4.28
2.2
1.9
—
—
—
0
0
66
384
1.73
4.28
2.2
1.9
—
—
—
0
0
70
415
1.69
4.25
1.3
1.3
163.32
181.80
pmol/l
0.33
70
415
266
2053
1.31
4.21
1.5
1.6
0.23
0.24
g/l
0.75
257
1952
273
2119
1.30
4.15
1.5
1.6
1.16
1.20
g/l
1.40
263
2017
338
2696
1.27
4.14
2.6
2.4
0.55
0.83
g/l
1.36
290
2331
617
7225
0.84
4.10
8.8
9.1
120.67
121.52
g/l
0.49
601
7057
508
4242
1.21
4.08
1.2
1.2
136.22
140.16
u/ml
0.08
175
1625
785
6812
1.17
4.08
2.2
2.1
0.00
0.02
estimate
2.81
166
1343
743
8559
0.85
4.05
7.9
8.2
0.58
0.98
mmol/l
2.41
637
7105
2010
18579
1.11
3.96
3.5
3.4
0.46
0.15
estimate
0.33
588
5690
2280
21218
1.11
3.95
3.1
3.1
1093.36
1204.15
ng/l
0.83
1959
18425
264
2058
1.29
3.91
2.6
2.4
0.00
0.00
g/l
-0.00
244
1936
307
2452
1.26
3.76
3.9
3.6
24.81
25.02
mmol/l
0.71
282
2243
756
8647
0.86
3.76
7.8
8.2
5.05
5.11
kpa
1.33
721
8350
756
8644
0.86
3.74
7.8
8.2
13.23
12.39
kpa
3.68
722
8340
136
973
1.41
3.58
1.1
1.1
14.94
18.12
au/ml
0.27
37
211
286
2285
1.26
3.51
2.5
2.4
0.00
0.03
g/l
2.37
259
2065
305
2456
1.25
3.50
1.9
1.8
—
—
—
0
0
733
6417
1.16
3.42
2.4
2.4
384.83
377.09
nmol/l
0.53
693
5961
46
259
1.78
3.41
3.0
2.8
0.63
0.61
mmol/l
1.09
46
259
211
1630
1.30
3.39
1.2
1.1
3.37
3.64
0.19
23
192
1494
13698
1.11
3.37
4.0
4.0
225.09
481.93
ng/l
2.68
1184
10875
8
14
5.72
3.34
1.0
1.0
—
—
—
0
0
676
7726
0.86
3.33
8.1
8.6
96.04
95.60
%
1.19
644
7473
275
2203
1.26
3.32
2.5
2.4
0.00
0.00
g/l
0.31
244
1940
58
352
1.65
3.31
1.1
1.2
—
—
—
0
0
195
1504
1.30
3.20
1.8
1.7
280.67
297.67
mu/l
0.44
184
1394
458
3883
1.19
3.19
2.1
1.8
—
—
—
0
0
538
4625
1.18
3.19
3.7
3.6
5.07
5.15
kpa
1.82
515
4434
2417
22750
1.09
3.17
3.8
3.5
66.54
69.88
e6/l
0.06
1800
17348
263
2111
1.25
3.14
2.0
2.2
94.38
91.92
%
0.96
249
2033
258
2067
1.26
3.14
3.5
2.8
1.60
1.56
mg/l
0.27
235
1896
47
276
1.71
3.05
2.7
2.1
—
—
—
0
0
14
343
0.41
3.03
25.0
19.1
1488.43
1406.21
nmol/l
0.28
14
332
2372
22351
1.09
3.00
2.8
2.7
64.14
65.83
u/l
0.15
2160
20783
105
743
1.42
3.00
1.5
1.4
0.27
0.27
nmol/l
0.02
80
511
107
760
1.41
3.00
1.1
1.1
1.35
3.00
u/ml
2.68
52
355
416
3522
1.19
2.97
2.1
1.8
—
—
—
0
0
37
205
1.81
2.93
1.5
1.7
1.93
1.05
u/ml
—
7
47
12
309
0.39
2.93
3.0
3.4
0.38
1.40
%
3.91
12
309
20
88
2.28
2.93
1.2
2.0
—
—
—
0
0
116
841
1.39
2.90
2.3
2.1
27.33
25.05
mg/l
0.16
41
308
642
5640
1.15
2.89
1.5
1.5
—
—
—
0
0
17
70
2.43
2.87
1.1
1.1
—
—
—
0
0
46
274
1.68
2.86
2.7
2.1
—
—
—
0
0
46
274
1.68
2.86
2.7
2.1
—
—
—
0
0
14
332
0.42
2.83
17.9
14.0
858.79
4758.78
nmol/l
0.49
14
317
100
710
1.41
2.83
1.1
1.1
1.96
3.64
u/ml
1.29
41
292
191
1498
1.28
2.80
6.9
5.6
1527.88
2217.99
iu/ml
0.16
32
224
113
1537
0.73
2.80
6.8
7.3
105.02
105.26
mmol/l
0.23
97
1379
113
1536
0.73
2.79
6.8
7.3
11.12
11.29
mmol/l
0.22
97
1378
124
917
1.36
2.76
1.3
1.5
—
—
—
0
0
309
2573
1.21
2.67
1.6
1.6
21.38
19.26
u/ml
0.17
66
566
143
1093
1.31
2.58
1.1
1.1
1.23
1.64
u/ml
0.38
71
579
22
107
2.06
2.56
2.1
2.0
—
—
—
0
0
125
939
1.34
2.54
1.3
1.5
—
—
—
0
0
15
62
2.42
2.53
1.0
1.4
—
—
—
0
0
47
292
1.61
2.52
28.9
28.4
103.11
113.35
ug/l
0.59
36
238
123
925
1.34
2.49
1.3
1.5
—
—
—
0
0
104
763
1.37
2.47
1.1
1.2
—
—
—
0
0
231
1884
1.23
2.47
1.9
1.9
35.84
6.94
iu/l
0.44
98
748
356
3028
1.18
2.46
1.8
1.6
25.46
16.22
iu/ml
0.44
11
72
15
64
2.35
2.38
1.2
1.0
—
—
—
0
0
118
889
1.33
2.38
1.3
1.5
—
—
—
0
0
3388
32596
1.07
2.38
15.6
14.6
1.26
1.25
inr
0.61
2803
27090
148
1151
1.29
2.38
1.6
1.3
138.98
156.82
au/ml
1.27
50
338
112
838
1.34
2.36
1.1
1.1
0.71
1.26
u/ml
1.03
54
400
118
891
1.33
2.35
1.3
1.5
—
—
—
0
0
605
5380
1.14
2.32
2.9
2.9
10.43
10.47
g/l
0.09
563
4968
101
747
1.36
2.31
1.1
1.2
22.43
37.53
u/ml
—
7
41
444
3869
1.16
2.29
3.6
3.4
1.54
1.96
mmol/l
1.89
327
2902
117
886
1.33
2.29
1.3
1.5
—
—
—
0
0
1282
11888
1.09
2.28
2.8
2.6
13.95
13.01
umol/l
4.48
1184
11122
87
630
1.39
2.27
1.1
1.2
79.17
73.76
u/ml
—
6
25
80
572
1.40
2.25
1.2
1.1
—
—
—
0
0
481
4228
1.15
2.21
1.9
2.0
1.29
1.33
g/l
0.16
443
3883
235
1946
1.21
2.21
2.4
2.5
202.38
198.93
%
0.24
222
1855
47
306
1.54
2.12
2.5
2.3
—
—
—
0
0
48
315
1.53
2.10
1.2
1.1
—
0.12
—
0
5
177
1433
1.24
2.08
1.4
1.4
11.88
11.70
u/l
0.05
141
1158
50
332
1.51
2.08
1.1
1.1
0.98
1.14
u/l
3.21
27
153
39
245
1.59
2.06
1.1
1.1
102.52
94.82
%
0.65
33
190
21
110
1.91
2.05
2.2
2.0
—
—
—
0
0
13
56
2.32
2.04
2.2
1.8
—
—
—
0
0
2741
26288
1.07
2.02
4.0
3.8
37.47
66.78
ng/l
0.98
1962
18796
203
1674
1.22
2.02
2.1
2.2
131.90
128.85
g/l
0.99
138
1266
914
8392
1.10
2.01
2.9
2.8
6.99
8.64
umol/l
1.89
819
7405
1112
10307
1.09
2.00
2.9
2.6
24.61
22.66
%
4.44
1022
9619
295
2526
1.17
1.95
1.4
1.3
35.70
36.05
iu/l
0.06
256
2184
85
631
1.35
1.95
2.0
1.7
—
—
—
0
0
85
631
1.35
1.95
2.0
1.7
—
—
—
0
0
85
631
1.35
1.95
2.0
1.7
—
—
—
0
0
9
33
2.73
1.93
2.8
4.7
—
—
—
0
0
21
113
1.86
1.91
1.7
1.6
124.81
123.57
ug/l
0.02
16
96
61
430
1.42
1.90
1.7
1.5
79.90
81.93
umol/l
0.26
61
430
17
85
2.00
1.89
6.9
11.7
5.02
5.11
mmol/l
0.07
17
85
52
357
1.46
1.87
1.1
1.1
—
1.38
—
0
7
253
2149
1.18
1.86
1.4
1.4
—
—
—
0
0
224
1885
1.19
1.83
1.5
1.3
—
—
—
0
0
115
902
1.28
1.81
1.1
1.1
0.58
1.03
u/ml
1.07
47
380
81
605
1.34
1.81
6.0
5.7
59.35
86.68
u/ml
0.27
24
204
16
80
2.00
1.79
1.0
1.1
—
—
—
0
0
205
1716
1.20
1.78
1.2
1.2
—
—
—
0
0
117
922
1.27
1.78
1.1
1.1
3.96
3.89
u/ml
0.02
53
450
206
1728
1.20
1.76
1.2
1.2
—
—
—
0
0
252
2154
1.18
1.74
1.3
1.3
—
—
—
0
0
1188
11113
1.08
1.74
2.8
2.6
2.29
2.32
g/l
0.73
1089
10306
240
2045
1.18
1.72
2.4
2.5
3.60
3.61
g/l
0.03
234
1953
18
96
1.88
1.70
1.8
1.6
—
—
—
0
0
60
435
1.38
1.64
7.0
6.9
13.60
112.46
ug/l
1.17
43
274
60
435
1.38
1.64
2.5
2.6
199.48
230.81
e6/l
0.94
54
377
28
173
1.62
1.63
1.1
1.1
—
—
—
0
0
40
269
1.49
1.63
1.8
2.1
710.40
4689.92
u/ml
—
5
40
1883
19730
0.94
1.61
4.4
4.1
0.00
0.00
estimate
0.45
696
6683
6
20
3.00
1.58
3.3
4.1
—
—
—
0
0
61
449
1.36
1.54
1.4
1.2
18.72
24.81
u/l
0.72
50
372
28
176
1.59
1.54
1.0
1.1
89.38
88.66
%
0.03
13
95
13
246
0.53
1.53
1.7
2.0
1247.40
19130.21
e6/l
—
5
130
897
8344
1.09
1.52
4.8
4.9
243.10
243.46
u/l
0.03
850
7920
52
374
1.39
1.51
1.1
1.1
—
—
—
0
0
670
6156
1.10
1.51
2.6
2.7
66.43
66.40
g/l
0.04
605
5665
192
1629
1.18
1.49
2.4
1.8
—
—
—
0
0
156
1299
1.21
1.49
1.2
1.3
508.00
346.40
titre
—
10
100
24
147
1.63
1.47
1.7
1.4
1.19
1.17
mmol/l
0.96
24
147
222
1910
1.17
1.46
2.8
3.3
1.60
2.12
index
0.76
109
977
28
179
1.57
1.45
1.0
1.1
86.08
87.38
%
0.07
13
92
37
252
1.47
1.44
1.2
1.1
—
—
—
0
0
6
22
2.73
1.43
2.3
1.4
—
—
—
0
0
290
2559
1.14
1.37
3.6
3.5
38.31
47.29
mg/l
0.65
251
2170
28
182
1.54
1.36
1.2
1.3
—
—
—
0
0
290
2561
1.14
1.35
3.6
3.5
39.86
72.64
mg/l
0.90
250
2172
228
1982
1.16
1.34
2.4
1.9
—
—
—
0
0
78
610
1.28
1.33
1.0
1.1
—
—
—
0
0
17
284
0.60
1.32
1.5
2.1
825.20
3555.33
e6/l
—
10
193
61
463
1.32
1.30
1.4
1.2
82.86
89.12
u/l
0.25
50
394
307
2730
1.13
1.30
1.2
1.3
0.18
1.00
u/ml
3.38
16
237
56
420
1.34
1.30
2.4
2.5
451.23
522.72
e6/l
0.70
48
346
14
76
1.84
1.29
1.1
1.0
5.51
9.19
u/ml
0.48
14
76
43
309
1.39
1.29
1.0
1.1
—
—
—
0
0
1185
11218
1.07
1.27
1.7
1.7
1103.33
1157.69
nmol/l
1.27
869
8585
756
8102
0.93
1.25
6.4
6.7
—
—
—
0
0
179
1537
1.17
1.25
1.4
1.4
40.07
37.69
e6/l
0.04
121
1126
6
25
2.40
1.24
3.7
1.8
2.90
1.35
mg/l
—
6
18
48
355
1.35
1.23
1.8
2.4
199.29
199.55
u/l
0.01
48
349
71
556
1.28
1.22
1.2
1.2
—
—
—
0
0
259
2289
1.14
1.22
3.5
3.4
1.61
2.55
ratio
2.33
141
1291
5
19
2.63
1.21
1.0
1.1
—
—
—
0
0
180
1553
1.16
1.20
1.6
1.6
—
—
—
0
0
181
1563
1.16
1.19
1.4
1.4
543.57
1636.63
e6/l
2.48
129
1231
58
445
1.31
1.17
1.4
1.4
—
—
—
0
0
98
802
1.22
1.17
1.3
1.2
55.37
64.78
u/l
0.94
81
698
1002
9464
1.07
1.17
6.7
5.7
1.03
1.03
mmol/l
0.02
917
8828
42
308
1.37
1.15
2.1
1.9
40.36
40.09
g/l
0.12
42
308
178
1541
1.16
1.14
1.1
1.1
5.52
8.12
eliau/ml
0.32
21
177
63
491
1.29
1.14
1.7
2.0
1.81
1.45
u/field
0.24
32
261
139
1180
1.18
1.14
3.5
2.6
82.00
2268.30
u/ml
—
5
77
1366
14295
0.95
1.12
1.7
1.7
32505044.86
32543877.06
pmol/l
0.00
1086
12027
95
780
1.22
1.11
4.2
3.8
56.98
57.55
%
0.09
83
676
43
319
1.35
1.10
1.5
1.4
—
1057556.13
—
0
8
73
906
0.80
1.08
1.5
1.6
—
—
—
0
0
62
487
1.28
1.07
1.3
1.3
0.95
1.49
u/ml
0.37
44
281
13
74
1.76
1.06
1.1
1.1
—
—
—
0
0
81
659
1.23
1.05
3.2
3.5
13.50
13.14
index
0.12
40
366
10
179
0.56
1.04
1.0
1.4
30.58
26.35
g/l
—
5
139
60
472
1.27
1.04
1.2
1.1
—
0.62
—
0
5
86
706
1.22
1.03
3.5
3.6
—
—
—
0
0
42
315
1.34
1.02
1.0
1.1
1702.57
1517.49
miu/ml
0.56
42
315
46
350
1.32
1.02
4.4
4.0
—
—
—
0
0
354
3228
1.10
1.01
1.7
1.7
1.49
1.60
g/l
1.32
305
2778
2402
23321
1.04
1.01
3.3
3.4
30.76
35.35
u/l
3.70
2286
21971
14
83
1.69
1.01
1.0
1.1
—
—
—
0
0
544
5845
0.93
1.00
3.1
2.7
67.40
66.43
ml/min/173m2
0.26
251
2425
305
2762
1.11
1.00
1.3
1.4
—
—
—
0
0
15
91
1.65
1.00
1.0
1.0
98.95
77.19
ug/l
—
10
70
40
299
1.34
1.00
1.2
6.4
64.88
1483.05
mg/l
0.80
26
220
237
2117
1.12
0.99
1.6
1.5
11.38
13.59
iu/ml
0.06
39
408
597
5577
1.08
0.98
2.7
3.0
137.45
184.60
ng/l
3.39
544
5116
5
23
2.17
0.98
1.0
1.0
0.01
0.03
u/ml
—
5
23
44
335
1.32
0.98
1.9
1.6
—
—
—
0
0
44
335
1.32
0.98
1.9
1.6
—
—
—
0
0
10
54
1.85
0.96
1.4
1.6
0.58
0.48
e9/l
—
10
54
49
380
1.29
0.96
1.6
1.6
10.78
9.43
umol/l
0.16
39
262
22
149
1.48
0.95
1.5
1.2
—
—
—
0
0
35
259
1.35
0.94
1.2
1.2
9.89
11.46
mm/h
0.34
35
259
9
51
1.77
0.94
8.7
5.6
—
—
—
0
0
165
1878
0.88
0.94
1.5
1.5
—
—
—
0
0
741
6990
1.07
0.93
3.2
3.5
—
—
—
0
0
6
27
2.22
0.93
1.8
1.3
748.27
491.50
nmol/l
—
6
27
138
1199
1.15
0.90
2.2
1.6
0.86
0.82
g/l
0.15
110
942
45
349
1.29
0.90
1.1
1.2
1.07
1.06
ratio
0.13
38
284
54
430
1.26
0.88
1.2
1.2
—
—
—
0
0
67
548
1.22
0.87
1.1
1.1
286.27
289.73
mg/l
0.17
62
493
210
1882
1.12
0.86
1.1
1.1
0.64
0.62
ratio
0.28
33
314
56
450
1.25
0.85
1.1
1.1
280.28
283.34
mg/l
0.03
47
405
22
153
1.44
0.85
1.2
1.1
1080.00
909.09
titre
—
5
33
43
335
1.29
0.84
1.3
1.2
0.60
0.56
ratio
0.26
26
208
774
8156
0.94
0.84
1.9
1.9
—
—
—
0
0
44
557
0.79
0.83
1.6
1.6
—
—
—
0
0
58
470
1.24
0.83
1.6
1.8
82.87
104.82
ng/l
1.91
58
470
670
6330
1.06
0.83
2.5
2.6
69.92
69.69
e9/l
0.05
466
4627
1212
11642
1.05
0.82
2.0
2.0
—
—
—
0
0
54
435
1.24
0.81
1.2
1.2
—
—
—
0
0
1624
15716
1.04
0.80
2.9
2.7
4.50
5.16
e6/l
1.34
1449
14345
13
200
0.65
0.79
1.2
1.1
—
—
—
0
0
6
33
1.82
0.79
1.0
1.3
—
—
—
0
0
283
2594
1.09
0.78
2.0
2.3
534.65
642.58
ug/l
0.15
273
2466
207
1868
1.11
0.78
1.3
1.3
—
—
—
0
0
12
74
1.62
0.78
1.1
1.0
—
—
—
0
0
7
123
0.57
0.77
1.4
1.2
0.24
2.10
mmol/l
—
7
88
21
148
1.42
0.77
1.8
1.3
134.78
73.39
mu/l
0.29
14
115
5
99
0.50
0.77
1.8
1.3
44.80
362.86
u/l
—
5
72
26
191
1.36
0.76
1.2
1.7
0.39
0.37
ug/l
0.06
18
138
27
200
1.35
0.76
3.3
2.4
0.47
1.01
ug/l
3.27
27
190
101
872
1.16
0.75
1.6
1.6
59.71
57.82
%
0.19
65
541
21
149
1.41
0.75
5.2
4.9
39.19
56.18
u/l
0.69
21
144
7
38
1.84
0.73
1.1
1.1
—
—
—
0
0
92
791
1.17
0.73
1.1
1.1
5.39
3.46
eliau/ml
0.28
48
338
7
39
1.80
0.72
1.0
1.1
—
—
—
0
0
209
1897
1.10
0.72
1.6
1.6
9553.52
14040.07
e6/l
0.87
129
1310
9
56
1.61
0.72
1.1
1.0
—
—
—
0
0
11
68
1.62
0.71
1.1
1.1
0.01
1.73
u/ml
—
5
40
19
134
1.42
0.71
2.6
3.7
138.19
153.79
ng/l
—
7
46
278
3015
0.92
0.71
5.1
5.5
0.91
0.87
%
0.56
263
2847
38
300
1.27
0.70
1.1
1.1
70.65
345.86
ng/l
1.71
11
80
51
418
1.22
0.69
1.1
1.1
—
—
—
0
0
9
59
1.53
0.68
1.9
2.0
2.66
1.45
mg/l
—
9
50
83
714
1.16
0.67
2.2
1.8
—
—
—
0
0
75
640
1.17
0.67
1.3
1.2
—
—
—
0
0
76
650
1.17
0.66
1.1
1.1
0.11
0.34
u/ml
0.82
22
217
29
223
1.30
0.66
1.6
1.5
87.93
56.01
ug/l
1.23
29
223
82
949
0.86
0.66
1.3
1.3
0.18
0.20
nmol/l
0.49
65
755
288
3105
0.92
0.65
3.5
3.4
24.93
25.26
mmol/l
0.95
280
3001
10
62
1.61
0.65
1.4
1.9
—
—
—
0
0
307
3300
0.93
0.64
4.8
5.2
1.59
1.62
%
0.16
291
3120
24
180
1.33
0.64
1.2
1.2
—
—
—
0
0
15
213
0.70
0.64
1.3
1.1
—
—
—
0
0
12
178
0.67
0.64
2.2
2.3
5.75
206.40
ug/l
0.68
12
178
56
468
1.20
0.64
1.2
1.2
43.04
40.94
mg/l
0.14
46
404
5
29
1.72
0.64
2.2
7.8
93.80
105.62
g/l
—
5
29
112
990
1.13
0.63
1.1
1.1
1.53
1.51
g/l
0.21
103
897
16
112
1.43
0.63
1.0
1.1
27.45
40.82
iu/ml
0.68
16
112
87
998
0.87
0.63
1.4
1.7
—
—
—
0
0
172
1561
1.10
0.62
1.3
1.2
3.77
3.74
mmol/l
0.16
167
1475
35
279
1.26
0.62
1.6
1.8
2.55
4.80
ug/l
0.97
30
189
41
334
1.23
0.60
1.5
1.5
—
—
—
0
0
41
334
1.23
0.60
1.5
1.5
—
—
—
0
0
78
675
1.16
0.60
2.8
2.8
—
—
—
0
0
1265
12263
1.04
0.59
3.1
3.5
0.82
0.81
mmol/l
1.16
1185
11598
8
52
1.54
0.59
1.5
1.8
—
—
—
0
0
8
52
1.54
0.59
1.0
1.0
—
—
—
0
0
11
72
1.53
0.59
1.1
1.1
—
—
—
0
0
50
418
1.20
0.58
1.1
1.1
11.31
10.80
nmol/l
—
6
86
436
4123
1.06
0.58
5.2
3.9
24.22
24.35
mmol/l
0.42
431
4086
52
437
1.19
0.57
1.0
1.1
6.63
10.30
iu/ml
0.63
12
116
365
3434
1.07
0.57
3.3
3.3
1.02
1.02
ratio
1.06
335
3114
144
1588
0.90
0.56
2.7
2.8
34.45
34.64
umol/l
0.03
134
1432
15
207
0.72
0.56
1.5
1.6
9.77
8.99
ug/l
0.49
15
207
37
301
1.23
0.56
1.2
1.3
158.73
167.67
mmol/24h
0.29
37
301
29
229
1.27
0.56
1.1
1.0
—
—
—
0
0
2518
24712
1.03
0.56
3.6
3.3
7.59
7.56
mmol/l
0.16
2121
20835
6
37
1.62
0.55
4.8
6.9
—
—
—
0
0
87
766
1.14
0.55
2.1
1.7
—
—
—
0
0
416
4393
0.94
0.55
10.0
10.6
16.10
16.02
%
0.24
402
4240
248
2307
1.08
0.54
3.8
3.2
913.03
369.80
mg/l
0.40
118
1032
71
815
0.87
0.54
1.1
1.2
6.60
7.56
mmol/l
2.80
52
714
219
2028
1.08
0.54
1.5
1.4
—
—
—
0
0
43
358
1.20
0.53
1.2
1.6
—
—
—
0
0
6
39
1.54
0.53
1.0
1.0
—
—
—
0
0
536
5117
1.05
0.52
1.7
1.7
—
—
—
0
0
172
1579
1.09
0.52
1.6
1.7
—
—
—
0
0
130
1432
0.91
0.51
1.3
1.4
—
—
—
0
0
78
885
0.88
0.51
1.1
1.1
—
—
—
0
0
562
5873
0.95
0.51
2.3
2.3
6.49
7.77
ug/l
1.29
494
5206
50
425
1.18
0.51
1.4
1.3
—
—
—
0
0
121
1336
0.90
0.50
3.7
1.5
1.01
0.87
nmol/l
1.05
103
1137
17
127
1.34
0.49
1.0
1.2
—
77.27
—
0
48
140
1280
1.10
0.48
1.1
1.3
45.37
33.59
u/l
0.37
124
1111
7
47
1.49
0.47
1.1
1.1
—
—
—
0
0
45
382
1.18
0.47
1.2
1.2
—
—
—
0
0
14
102
1.37
0.47
1.2
1.3
63.28
43.84
mg/l
0.95
14
88
20
255
0.78
0.46
2.9
2.9
29.13
28.19
umol/l
0.07
15
194
101
1119
0.90
0.46
1.3
1.3
0.52
0.23
nmol/l
—
6
81
63
551
1.14
0.46
1.0
1.0
699.22
731.12
ng/l
0.23
46
376
63
552
1.14
0.45
1.0
1.0
346.63
312.44
ng/l
0.48
49
391
11
77
1.43
0.45
1.1
1.1
—
—
—
0
0
190
1769
1.08
0.44
1.3
1.3
491.08
560.16
mg/l
2.21
184
1685
10
69
1.45
0.44
1.1
1.0
—
—
—
0
0
105
952
1.10
0.44
1.1
1.1
123.73
117.66
%
1.23
95
860
65
736
0.88
0.44
3.3
4.4
7.46
7.22
mmol/l
0.17
54
631
63
554
1.14
0.43
1.0
1.0
46.54
39.80
ng/l
0.61
49
386
17
130
1.31
0.43
1.0
1.3
116.41
104.11
%
0.85
17
123
239
2245
1.07
0.43
1.5
1.4
273.31
274.04
ug/g
0.02
141
1343
21
166
1.27
0.43
5.0
7.2
6.59
5.18
kpa
1.13
21
166
38
447
0.85
0.43
2.1
1.8
—
—
—
0
0
33
276
1.20
0.42
1.2
1.4
—
—
—
0
0
20
158
1.27
0.41
1.6
1.2
181.92
326.16
pmol/l
3.22
13
119
13
96
1.35
0.41
2.4
2.5
14.88
60.74
mg/l
—
6
16
111
1014
1.10
0.41
1.2
1.2
3.15
4.11
u/ml
0.44
53
443
11
79
1.39
0.40
1.2
1.2
—
—
—
0
0
108
1181
0.91
0.40
1.5
1.4
16.48
12.52
u/ml
—
6
22
5
34
1.47
0.40
1.0
1.1
8.08
8.10
mmol/l
—
5
34
5
34
1.47
0.40
1.0
1.0
—
—
—
0
0
12
88
1.36
0.40
1.2
1.2
—
—
—
0
0
2421
23853
1.02
0.39
3.6
3.4
37.96
43.25
mg/l
0.63
1469
14986
39
334
1.17
0.39
1.1
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
3.21
—
0
19
45
391
1.15
0.38
2.4
2.7
45.18
38.62
%
1.45
27
227
63
705
0.89
0.37
1.4
1.3
—
—
—
0
0
9
69
1.30
0.37
1.0
1.0
—
—
—
0
0
111
1021
1.09
0.37
5.8
6.6
10.85
12.00
mg/l
2.41
104
949
2454
24201
1.02
0.37
4.3
4.0
6.51
7.58
mg/mmol
0.66
1454
14841
62
553
1.12
0.37
2.2
2.8
24.49
32.20
mg/l
0.95
43
396
49
431
1.14
0.36
1.4
1.5
4.98
6.21
u/l
1.67
44
373
23
189
1.22
0.36
1.1
1.1
—
1.43
—
0
7
6
42
1.43
0.35
1.0
1.0
—
—
—
0
0
63
702
0.90
0.35
1.4
1.6
—
—
—
0
0
59
528
1.12
0.34
1.5
1.6
24.33
24.03
u/ml
—
9
95
137
1279
1.07
0.33
2.6
3.9
59.02
29.93
u/ml
0.51
129
1245
94
864
1.09
0.33
1.1
1.1
2.44
3.03
0.21
12
127
103
953
1.08
0.32
1.5
1.4
—
—
—
0
0
131
1224
1.07
0.31
3.8
3.6
1.13
1.67
%
1.25
118
1102
63
570
1.11
0.31
1.1
1.2
175.00
148.88
titre
—
6
98
63
695
0.91
0.31
1.5
1.4
180280.71
105531.64
e6/l
0.33
45
464
108
1162
0.93
0.31
1.3
1.5
—
—
—
0
0
17
138
1.23
0.30
1.1
1.1
—
—
—
0
0
22
184
1.20
0.30
2.0
1.7
—
—
—
0
0
41
362
1.13
0.30
1.1
1.1
—
—
—
0
0
15
120
1.25
0.30
1.2
1.7
—
—
—
0
0
37
420
0.88
0.29
1.3
1.5
61.52
59.63
ug/l
0.10
27
334
71
649
1.09
0.29
1.4
1.5
27.55
32.12
%
0.52
43
387
64
583
1.10
0.28
1.2
1.2
118.89
110.41
pmol/l
0.76
64
583
30
260
1.15
0.28
1.0
1.1
—
—
—
0
0
20
167
1.20
0.28
1.1
1.1
—
—
—
0
0
2637
26644
0.98
0.27
4.0
3.9
0.83
0.34
estimate
0.26
622
5886
24
205
1.17
0.27
1.0
1.3
134.99
134.77
nmol/l
0.00
16
153
72
781
0.92
0.26
1.4
1.4
282.98
277.59
mosm/kgh2o
1.09
52
592
41
458
0.89
0.26
1.5
1.6
7.23
6.75
u/l
0.05
27
369
39
437
0.89
0.26
1.4
1.6
—
—
—
0
0
12
95
1.26
0.26
1.0
1.0
—
—
—
0
0
123
1158
1.06
0.26
1.2
1.2
1.36
0.90
—
7
36
25
216
1.16
0.25
1.4
1.2
371.28
265.77
ug/l
—
10
106
69
636
1.09
0.25
1.4
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
29
330
0.88
0.25
1.2
1.1
—
—
—
0
0
9
75
1.20
0.25
1.2
1.1
—
—
—
0
0
95
1015
0.94
0.24
1.5
1.5
36.43
33.01
g/l
2.31
86
916
173
1649
1.05
0.24
3.0
3.1
8.31
8.05
kpa
1.49
168
1617
12
96
1.25
0.24
1.2
1.6
—
1.14
—
0
7
40
360
1.11
0.23
1.6
1.3
1.16
1.30
nmol/l
0.32
26
273
20
171
1.17
0.23
1.1
1.1
—
—
—
0
0
19
162
1.17
0.22
1.1
1.1
—
—
—
0
0
7
91
0.77
0.22
1.3
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.5
273.00
345.07
umol/24h
—
5
40
1696
16761
1.02
0.22
3.9
3.7
0.15
0.22
0.24
13
155
148
1412
1.05
0.21
1.3
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
232.18
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
38
419
0.91
0.21
1.4
1.6
—
—
—
0
0
5
43
1.16
0.21
1.0
1.2
—
—
—
0
0
259
2677
0.97
0.20
1.6
1.7
0.26
0.33
mg/l
1.15
119
1280
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
27.93
—
0
14
0
14
0.00
0.20
0.0
12.1
—
—
—
0
0
44
480
0.92
0.20
2.1
2.3
766.85
641.67
ml
0.58
27
345
13
108
1.20
0.20
5.8
6.9
7.78
7.85
mmol/l
0.03
13
108
50
461
1.09
0.19
1.3
1.4
—
—
—
0
0
600
5880
1.02
0.19
2.7
2.5
0.28
0.46
e6/l
2.69
568
5642
820
8064
1.02
0.19
3.9
4.5
57.03
24.16
ug/l
0.48
644
6636
24
212
1.13
0.19
1.5
1.2
38.11
38.76
g/l
0.07
11
101
858
8720
0.98
0.19
1.8
1.9
—
—
—
0
0
6
51
1.18
0.19
1.2
1.2
49.83
10.39
u/l
—
6
51
12
143
0.84
0.18
1.5
2.3
5.66
7.93
mmol/l
—
7
81
597
5858
1.02
0.18
3.7
3.1
4.62
4.53
kpa
0.44
584
5709
7
58
1.21
0.18
1.1
1.1
96.00
91.03
titre
—
7
58
7
58
1.21
0.18
1.1
2.2
1.00
0.62
u/field
—
7
58
7
58
1.21
0.18
1.0
1.2
—
—
—
0
0
7
59
1.19
0.18
1.1
1.4
8.74
21.79
pmol/l
—
7
54
21
185
1.14
0.18
1.2
1.3
40.79
35.95
%
0.37
14
122
108
1029
1.05
0.18
1.2
1.2
7.40
2.93
u/ml
1.19
47
357
702
7139
0.98
0.17
2.2
2.3
0.21
0.21
g/l
1.04
670
6685
22
246
0.89
0.16
1.0
1.2
—
—
—
0
0
8
71
1.13
0.16
1.0
1.0
—
—
—
0
0
40
432
0.93
0.16
1.1
1.2
90.33
80.38
u/l
0.24
35
379
141
1464
0.96
0.16
2.2
2.2
182.55
99.22
ug/min
0.69
76
875
13
111
1.17
0.15
1.0
1.3
—
—
—
0
0
6
80
0.75
0.15
1.2
1.5
—
—
—
0
0
739
7498
0.98
0.15
1.7
1.8
1.42
1.50
%
2.44
660
6491
10
119
0.84
0.15
3.2
3.0
14.95
14.92
ml/dl
—
10
113
49
458
1.07
0.15
1.5
1.4
—
—
—
0
0
190
1842
1.03
0.15
1.8
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
236
2424
0.97
0.15
3.0
3.1
0.33
0.35
iu/ml
0.32
125
1324
281
2878
0.98
0.14
3.3
3.7
441.75
1390.94
u/ml
1.36
240
2505
568
5589
1.02
0.14
3.7
4.0
1.23
1.23
mmol/l
1.06
475
4897
82
782
1.05
0.14
1.7
1.8
90.57
89.62
%
1.13
82
770
40
429
0.93
0.14
1.1
1.2
25.96
23.22
u/l
0.09
35
378
375
3679
1.02
0.13
3.1
4.0
41.97
62.41
u/ml
0.93
360
3546
93
892
1.04
0.13
2.0
2.3
32.53
32.76
pg
0.21
93
887
16
180
0.89
0.13
1.1
1.2
5.90
9.84
pmol/l
—
7
72
100
961
1.04
0.13
2.0
1.9
6190.89
3465.76
u/l
0.22
32
374
20
180
1.11
0.13
1.1
1.1
—
—
—
0
0
197
2023
0.97
0.13
1.8
1.8
—
—
—
0
0
65
683
0.95
0.13
1.3
1.3
355.95
386.21
u/l
0.21
65
649
171
1662
1.03
0.12
3.3
3.7
66.24
791.89
u/ml
3.32
153
1506
87
906
0.96
0.12
1.5
1.6
—
—
—
0
0
52
492
1.06
0.12
1.9
2.0
—
—
—
0
0
185
1899
0.97
0.12
1.9
1.7
—
—
—
0
0
15
168
0.89
0.11
1.3
1.6
—
—
—
0
0
161
1653
0.97
0.11
1.4
1.5
—
—
—
0
0
14
157
0.89
0.11
1.7
1.3
13.79
25.45
%
1.89
14
136
16
144
1.11
0.10
1.3
1.1
—
—
—
0
0
103
998
1.03
0.10
1.1
1.1
—
—
—
0
0
37
392
0.94
0.10
1.6
2.0
8.44
7.84
mmol/l
0.54
37
392
5
44
1.14
0.10
12.4
5.3
—
—
—
0
0
53
506
1.05
0.09
1.6
1.4
11.72
12.18
u/l
0.24
53
488
15
135
1.11
0.09
6.1
7.1
10.82
10.32
%
0.48
15
135
20
184
1.09
0.09
1.3
1.2
—
—
—
0
0
29
309
0.94
0.09
1.4
2.1
69.13
133.65
umol/l
1.68
16
147
49
468
1.05
0.09
1.5
1.4
—
—
—
0
0
449
4437
1.01
0.08
3.8
3.3
129.58
129.57
g/l
0.00
435
4303
5
60
0.83
0.08
1.6
1.4
—
—
—
0
0
294
2983
0.98
0.08
1.8
2.0
1.23
1.90
ug/l
0.79
251
2676
10
88
1.14
0.08
4.3
5.2
55.80
47.60
ug/min
—
10
68
37
389
0.95
0.08
1.3
1.4
—
—
—
0
0
201
2044
0.98
0.07
1.3
1.2
246.67
164.01
titre
0.20
15
202
126
1288
0.98
0.07
1.4
1.3
—
—
—
0
0
126
1288
0.98
0.07
1.4
1.3
—
—
—
0
0
24
255
0.94
0.07
1.3
1.2
—
—
—
0
0
10
89
1.12
0.06
1.2
1.6
—
—
—
0
0
135
1376
0.98
0.06
3.6
4.3
2.37
2.66
mmol/l
0.62
106
955
702
7069
0.99
0.06
4.7
3.8
5.75
5.82
kpa
1.30
688
6899
28
266
1.05
0.06
1.1
1.2
—
—
—
0
0
28
294
0.95
0.06
2.0
1.8
—
—
—
0
0
100
1021
0.98
0.05
1.5
1.3
273.42
341.63
pmol/l
1.25
89
867
32
306
1.05
0.05
2.0
2.1
11.11
212.59
ug/min
—
9
63
14
129
1.09
0.05
1.0
1.3
—
—
—
0
0
38
395
0.96
0.05
1.3
1.4
1.08
1.11
ratio
0.09
22
239
38
395
0.96
0.05
1.3
1.4
0.95
0.98
ratio
0.15
22
239
38
395
0.96
0.05
1.3
1.4
1.15
1.22
ratio
0.22
22
239
45
465
0.97
0.05
1.4
1.5
—
—
—
0
0
24
228
1.05
0.05
2.1
2.0
22.96
29.90
%
1.96
24
211
86
877
0.98
0.04
1.6
1.4
1735.47
3280.77
e6/l
0.78
58
601
20
211
0.95
0.04
1.5
1.3
4.00
3.29
mmol/l
0.57
20
189
51
524
0.97
0.04
2.1
1.8
348.18
334.70
mu/l
0.14
45
405
210
2078
1.01
0.04
1.4
1.3
—
—
—
0
0
33
342
0.96
0.04
1.5
1.5
—
—
—
0
0
646
6492
0.99
0.04
8.4
7.2
9.68
9.73
mmol/l
0.08
616
6229
78
795
0.98
0.04
1.6
1.4
40.67
33.84
u/l
0.78
64
641
27
281
0.96
0.04
1.9
2.1
52.36
58.64
ug/l
0.34
27
275
130
1317
0.99
0.03
1.3
1.4
54.95
62.02
mmol/l
1.78
109
1041
33
319
1.03
0.03
1.5
1.7
2.35
2.70
u/field
0.09
20
221
100
985
1.02
0.03
1.1
1.1
50.53
12008.30
iu/ml
0.54
27
198
657
6542
1.00
0.03
7.7
8.3
1.27
1.31
mmol/l
0.47
648
6422
162
1603
1.01
0.03
1.4
1.5
—
—
—
0
0
11
102
1.08
0.03
2.2
2.2
21.01
18.31
umol/l
0.46
11
102
96
973
0.99
0.03
1.2
1.1
—
—
—
0
0
44
430
1.02
0.02
1.5
1.8
—
—
—
0
0
13
138
0.94
0.02
1.1
1.3
0.49
127.82
mg/l
—
6
100
139
1377
1.01
0.02
3.6
3.1
0.78
0.80
nmol/l
0.21
112
1103
74
750
0.99
0.02
1.2
1.2
—
41.11
—
0
9
689
6873
1.00
0.02
4.7
3.8
1.71
1.89
mmol/l
0.75
603
6064
15
143
1.05
0.01
1.2
1.2
—
—
—
0
0
39
397
0.98
0.01
1.4
1.6
13.11
8.89
ug/l
0.30
34
360
137
1363
1.01
0.00
2.8
3.4
25.92
27.75
mg/l
0.22
87
928
39
384
1.02
0.00
1.1
1.1
24.17
17.08
u/ml
0.66
16
148
69
684
1.01
0.00
1.5
1.5
1053.18
999.16
mu/l
0.18
55
542
79
784
1.01
0.00
1.6
1.4
94424.70
54740.46
e6/l
0.50
43
427
156
1554
1.00
0.00
1.3
1.3
241.57
217.10
miu/ml
0.31
69
665
257
2576
1.00
0.00
2.5
2.7
—
—
—
0
0
21
213
0.99
0.00
2.0
3.3
10.00
10.24
kpa
0.21
21
213
21
213
0.99
0.00
2.0
3.3
5.14
4.88
kpa
0.63
21
213
24
236
1.02
0.00
1.1
1.5
72.33
399.87
nmol/24h
1.57
24
236
127
1267
1.00
0.00
2.0
1.8
—
—
—
0
0
13
135
0.96
0.00
1.2
1.2
91.60
59.52
u/ml
0.53
13
130
19
195
0.97
0.00
1.4
1.2
—
—
—
0
0
449
4494
1.00
0.00
9.3
10.3
24.24
24.33
mmol/l
0.30
441
4422
15
151
0.99
0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
18.67
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
46.98
—
0
6
7
71
0.99
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINALBREAK and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINALBREAK | 0.725 [0.65, 0.81] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.329 |
During the follow-up period (1.1.1998 — 31.12.2019), 1190 out of 17611 females with H7_RETINALBREAK died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINALBREAK | 0.638 [0.57, 0.71] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 1476 out of 14412 males with H7_RETINALBREAK died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINALBREAK.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.062% | 0.134% |
| 5 | 0.415% | 0.759% |
| 10 | 1.058% | 1.968% |
| 15 | 2.039% | 3.615% |
| 20 | 3.557% | 6.424% |
Relationships between endpoints
↥Index endpoint: H7_RETINALBREAK – Retinal breaks without detachment
GWS hits: 7
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data