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R14

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Alpha 1 globulin [Mass/time] in 24 hour Urine by Electrophoresis

Number of people
669 (47.53% female)
People with ≥2 records
93.27%
Median duration from first to last measurement
0.17 years

Coding

Definition

OMOP Concept ID
3018461— open in OHDSI Athena.
Part of collection
Alpha 1 globulin with 1 other OMOP concept — open in OHDSI Athena.

OMOP mapping QC

OMOP concept ID Test name Measurement unit (harmonized unit) N people N records Missing measurement value Harmonized value distribution
Test outcome
NA
N
A
AA
L
LL
H
HH
3018461 cu-a1miglo — (—) 659 2205 100.00% Distribution not available
3018461 cu-a1miglo ug/min (ug/min) 478 1299 0.00%
3018461 cu-a1migl ug/min (ug/min) 38 61 0.00%
3018461 cu-a1migl — (—) 21 22 100.00% Distribution not available

Cohort

Number of people
669 (47.53% female)

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

People with ≥2 records
93.27%
Median number of measurements per person
2.0
Median duration from first to last measurement
0.17 years

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Reference range
N people
N records
—
662
3543
mies
26
26
nainen
17
18

Value range per person

LabWAS

Endpoint
People with measurements
Mean N measurements
Mean measured value
Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
351
191
16.78
307.65
7.4
2.8
42.42
49.73
ug/min
0.55
302
128
505
119
31.35
307.65
6.3
2.3
48.10
19.95
ug/min
11.09
433
49
508
48
91.89
307.65
6.3
3.0
48.93
21.50
ug/min
8.46
441
28
296
35
89.57
307.65
7.3
3.6
51.05
33.30
ug/min
2.25
269
26
277
13
224.20
307.65
7.3
2.8
53.11
20.38
ug/min
—
254
8
523
60
70.60
307.65
6.2
2.3
46.19
20.21
ug/min
7.61
445
27
494
116
28.73
307.65
6.2
2.2
45.83
18.71
ug/min
9.89
418
46
272
38
75.89
307.65
7.9
3.6
42.50
56.79
ug/min
0.53
244
30
275
97
29.07
307.65
8.0
3.2
39.68
45.83
ug/min
0.35
243
63
273
39
74.69
307.65
7.9
3.7
41.83
65.31
ug/min
0.91
245
29
230
26
94.80
307.65
7.3
4.5
53.44
40.14
ug/min
1.00
214
21
471
28
166.47
307.65
6.4
3.3
46.71
23.18
ug/min
4.36
412
17
253
68
38.34
307.65
6.8
4.0
49.22
58.51
ug/min
0.43
221
49
229
18
133.28
307.65
7.8
4.4
41.68
30.92
ug/min
0.77
192
12
148
19
78.95
277.50
6.2
2.9
63.70
21.60
ug/min
—
132
10
164
43
39.37
268.33
6.9
4.1
53.21
57.03
ug/min
0.12
145
32
154
50
31.62
236.95
8.2
3.5
46.85
60.15
ug/min
0.61
139
40
143
43
34.38
225.31
6.8
4.9
37.70
61.63
ug/min
1.33
122
32
350
205
9.53
214.10
6.9
2.8
43.45
48.43
ug/min
0.35
285
137
293
214
9.25
197.19
6.5
4.6
49.03
39.79
ug/min
1.09
264
147
339
205
8.94
195.74
6.8
2.8
44.13
48.43
ug/min
0.28
271
137
176
91
16.39
187.69
6.4
2.3
43.24
20.87
ug/min
5.13
148
41
94
24
40.70
154.75
7.6
6.5
36.56
42.29
ug/min
0.15
78
19
94
25
38.97
153.08
7.6
6.6
36.56
41.13
ug/min
0.12
78
20
298
219
7.34
150.45
6.7
3.1
41.50
48.77
ug/min
0.55
235
148
231
127
10.30
149.44
6.2
3.7
45.57
33.94
ug/min
1.15
175
87
231
127
10.30
149.41
6.2
3.7
45.57
33.94
ug/min
1.15
175
87
181
70
15.12
144.29
6.3
3.7
44.04
32.36
ug/min
0.70
133
43
172
163
9.66
140.79
6.1
4.9
50.45
42.66
ug/min
0.61
152
116
173
172
9.17
135.97
6.1
4.9
50.78
42.08
ug/min
0.74
153
122
156
163
9.04
123.40
6.3
5.4
51.81
41.93
ug/min
0.92
139
126
155
162
9.08
123.29
6.3
5.4
51.45
41.99
ug/min
0.86
138
125
169
187
8.29
123.28
6.2
5.1
50.92
41.65
ug/min
0.92
150
142
83
33
25.43
118.91
8.1
2.4
37.75
37.92
ug/min
0.00
71
20
105
19
35.66
117.06
6.2
5.1
49.79
15.33
ug/min
5.64
85
12
106
76
13.92
114.31
6.9
6.7
44.31
48.54
ug/min
0.18
96
57
100
70
14.28
109.40
7.0
5.9
44.90
52.31
ug/min
0.32
91
51
185
121
8.67
108.05
5.7
3.7
49.25
31.68
ug/min
2.02
138
82
281
337
4.93
104.87
6.3
4.6
51.70
33.48
ug/min
3.81
241
227
123
128
9.62
104.74
6.1
5.3
48.50
58.15
ug/min
0.64
111
106
210
269
5.77
101.31
5.8
5.0
55.81
37.93
ug/min
2.54
180
192
102
82
12.20
100.55
7.7
5.5
35.51
47.29
ug/min
0.75
85
55
154
171
7.48
98.83
6.0
5.0
56.46
40.94
ug/min
1.48
136
124
105
96
11.06
98.82
7.5
5.7
34.57
47.43
ug/min
0.95
83
70
225
297
5.26
96.42
5.8
4.9
53.65
36.00
ug/min
2.91
191
207
218
297
5.26
94.58
5.9
4.8
52.68
37.61
ug/min
2.21
186
209
109
112
9.81
94.50
6.0
4.9
49.17
62.96
ug/min
0.90
99
92
123
117
9.09
93.46
6.1
5.3
48.50
46.11
ug/min
0.14
111
93
93
28
21.71
91.96
5.6
3.3
52.85
30.99
ug/min
2.33
85
17
156
104
8.61
91.41
6.2
3.7
38.72
33.36
ug/min
0.26
116
57
83
59
14.22
91.18
8.1
4.7
37.75
36.18
ug/min
0.06
71
36
224
303
5.00
90.05
5.7
4.9
54.74
34.15
ug/min
3.67
185
210
149
207
6.62
89.82
5.4
5.7
63.50
41.82
ug/min
2.60
129
166
178
275
5.63
89.59
6.2
5.2
46.36
42.54
ug/min
0.29
148
210
152
242
6.21
88.78
6.3
5.4
48.32
39.00
ug/min
0.95
130
175
132
147
7.73
88.62
5.9
5.1
60.39
43.77
ug/min
1.39
117
110
91
79
11.64
88.61
6.0
4.8
44.70
59.83
ug/min
0.95
83
63
141
163
7.23
88.21
5.9
5.1
58.94
41.38
ug/min
1.67
125
120
206
243
5.36
86.36
6.3
5.4
47.69
41.34
ug/min
0.61
180
178
124
45
13.86
85.81
5.8
2.4
44.29
20.95
ug/min
2.88
91
22
93
88
10.66
85.49
6.3
5.0
46.35
63.71
ug/min
1.04
85
72
243
363
4.44
84.93
6.3
4.8
49.14
39.67
ug/min
1.31
213
260
105
86
10.09
83.22
6.4
5.2
58.92
37.65
ug/min
1.53
93
65
105
124
8.48
80.68
6.4
5.3
58.92
41.56
ug/min
1.24
93
99
100
115
8.72
79.36
6.3
4.9
55.59
40.56
ug/min
1.19
86
81
146
85
8.63
79.20
5.8
3.8
43.80
26.56
ug/min
1.65
102
52
146
85
8.63
79.20
5.8
3.8
43.80
26.56
ug/min
1.65
102
52
84
77
10.99
78.87
6.3
5.0
56.35
39.39
ug/min
1.16
74
56
84
77
10.99
78.87
6.3
5.0
56.35
39.39
ug/min
1.16
74
56
115
77
9.74
78.75
5.5
3.5
46.68
32.51
ug/min
0.95
94
44
67
44
15.44
76.86
7.2
5.5
36.92
59.46
ug/min
1.08
61
37
104
124
7.96
74.72
5.8
5.5
65.08
42.91
ug/min
1.66
95
103
238
360
4.14
74.60
6.2
4.8
49.34
39.09
ug/min
1.35
206
250
59
34
17.32
71.60
6.6
3.2
67.24
23.91
ug/min
3.32
50
23
126
74
8.92
71.58
6.2
3.0
41.84
27.56
ug/min
0.88
91
37
95
113
8.16
70.32
5.9
5.3
66.29
44.91
ug/min
1.39
87
93
130
137
6.64
69.79
5.4
4.3
50.69
42.39
ug/min
0.60
121
103
151
241
5.15
67.85
5.9
4.9
54.17
39.49
ug/min
1.50
137
182
164
287
4.76
67.69
6.1
5.6
54.12
43.17
ug/min
1.12
148
220
141
228
5.23
65.22
6.0
5.0
52.08
40.65
ug/min
1.03
129
173
120
211
5.71
64.82
6.5
5.5
51.61
45.82
ug/min
0.38
110
155
96
128
7.10
62.55
5.1
6.9
56.92
36.03
ug/min
2.08
88
100
124
90
7.33
62.36
6.1
3.9
42.33
31.44
ug/min
0.60
87
51
70
38
13.51
61.93
5.8
3.8
44.51
43.75
ug/min
0.03
63
28
121
224
5.43
61.87
6.6
5.5
51.37
45.69
ug/min
0.39
111
166
164
349
4.27
61.30
6.1
5.3
54.12
43.81
ug/min
1.07
148
265
219
306
3.90
60.49
6.3
4.9
44.40
42.73
ug/min
0.12
185
222
114
188
5.71
60.25
5.7
5.8
59.14
42.56
ug/min
1.53
97
151
115
191
5.66
60.08
5.7
5.8
58.59
42.08
ug/min
1.54
98
154
221
315
3.81
59.15
6.4
4.9
44.08
42.73
ug/min
0.09
186
229
241
381
3.51
58.42
5.9
5.0
46.03
44.85
ug/min
0.08
189
290
65
30
15.01
58.24
6.7
5.1
43.64
37.23
ug/min
0.26
55
22
64
31
14.60
57.30
7.3
4.2
48.19
34.93
ug/min
0.44
58
18
187
274
4.07
56.59
5.9
5.0
45.44
44.07
ug/min
0.09
156
202
173
269
4.14
55.09
5.9
5.3
43.77
40.93
ug/min
0.25
145
197
134
183
5.03
54.71
6.8
3.4
49.59
48.19
ug/min
0.07
116
131
206
325
3.67
53.82
5.7
5.1
44.96
40.42
ug/min
0.41
160
228
205
327
3.64
53.14
5.6
5.2
45.18
40.27
ug/min
0.46
159
230
52
42
12.50
52.95
5.9
6.2
59.11
54.13
ug/min
0.11
46
31
199
333
3.59
51.29
5.0
5.7
54.11
35.81
ug/min
2.76
157
245
139
323
4.16
51.28
6.1
5.4
53.31
43.32
ug/min
0.90
127
245
194
305
3.69
51.17
5.8
5.3
43.27
40.30
ug/min
0.25
152
219
188
300
3.72
50.71
6.1
5.2
44.99
41.18
ug/min
0.34
156
214
162
389
3.73
50.17
6.1
5.2
42.66
43.62
ug/min
0.07
135
297
171
269
3.87
49.07
5.8
5.0
46.23
44.17
ug/min
0.14
145
199
170
269
3.85
48.33
5.9
5.0
46.40
44.17
ug/min
0.15
144
199
209
419
3.26
48.25
6.0
5.0
46.48
42.95
ug/min
0.31
176
309
182
290
3.67
47.98
5.9
4.8
47.86
46.54
ug/min
0.09
149
219
182
290
3.67
47.98
5.9
4.8
47.86
46.54
ug/min
0.09
149
219
79
125
6.34
47.53
7.4
5.7
50.18
40.59
ug/min
0.55
71
89
182
305
3.61
47.40
5.8
5.2
46.34
45.21
ug/min
0.08
154
230
75
113
6.67
47.32
7.3
5.6
51.03
37.68
ug/min
0.86
69
82
73
109
6.73
46.46
7.3
5.7
50.93
34.92
ug/min
1.11
68
78
195
407
3.29
46.38
6.0
5.1
45.08
43.74
ug/min
0.10
163
300
210
432
3.16
46.13
6.0
5.1
46.24
42.65
ug/min
0.33
177
321
77
125
6.19
45.28
7.9
6.0
41.93
43.88
ug/min
0.11
69
97
207
315
3.34
45.25
6.2
4.9
48.43
42.73
ug/min
0.49
168
229
195
459
3.16
44.71
6.2
5.1
42.90
44.13
ug/min
0.11
158
347
102
135
5.31
44.58
4.9
5.4
49.58
49.23
ug/min
0.01
95
108
204
372
3.22
44.54
5.7
5.0
47.33
44.11
ug/min
0.25
159
284
92
64
7.22
44.40
5.7
4.0
39.45
32.59
ug/min
0.20
65
33
134
145
4.67
44.31
5.2
5.6
47.55
27.29
ug/min
2.42
97
91
140
358
3.72
44.00
7.5
4.9
36.62
43.62
ug/min
0.74
115
259
209
423
3.05
42.70
6.0
5.1
46.56
43.02
ug/min
0.31
174
311
157
386
3.44
42.61
6.3
5.1
44.96
46.09
ug/min
0.08
135
291
133
231
4.02
42.11
5.3
5.5
50.15
47.47
ug/min
0.17
123
188
184
340
3.28
41.83
5.4
5.4
46.61
37.94
ug/min
1.05
148
238
171
298
3.44
41.53
5.6
5.3
46.62
44.98
ug/min
0.11
145
223
133
234
3.96
41.36
5.3
5.5
50.62
47.23
ug/min
0.22
123
190
195
371
3.13
41.05
6.1
5.0
45.68
41.54
ug/min
0.39
163
268
38
28
13.66
40.77
6.0
5.0
44.22
33.52
ug/min
0.51
32
21
38
28
13.66
40.77
6.0
5.0
44.22
33.52
ug/min
0.51
32
21
166
229
3.64
40.68
5.4
4.6
44.70
36.24
ug/min
0.81
127
155
167
287
3.44
40.48
5.7
5.1
44.45
45.16
ug/min
0.05
139
213
198
442
2.99
40.01
6.1
5.1
44.61
44.30
ug/min
0.02
166
330
135
388
3.48
39.17
6.2
5.2
40.87
41.43
ug/min
0.04
110
292
131
212
3.91
38.65
7.1
4.9
43.74
47.22
ug/min
0.21
111
162
60
44
8.82
38.51
5.8
4.2
50.54
33.75
ug/min
0.96
50
28
74
132
5.49
38.14
5.2
5.3
46.74
38.40
ug/min
0.56
60
94
49
59
8.36
37.66
6.0
4.7
61.07
49.98
ug/min
0.41
44
46
182
293
3.14
36.25
6.3
4.9
46.21
43.22
ug/min
0.21
148
212
35
28
12.61
35.78
6.3
5.6
56.76
45.82
ug/min
0.23
29
23
83
179
4.58
34.90
7.4
5.5
49.49
40.90
ug/min
0.54
75
128
44
51
8.70
34.88
8.1
5.6
38.68
46.43
ug/min
0.29
38
38
97
160
4.34
34.26
5.5
6.3
52.40
40.37
ug/min
0.90
84
125
97
160
4.34
34.22
5.5
6.3
52.40
40.37
ug/min
0.90
84
125
143
264
3.37
34.20
6.7
4.9
48.27
42.08
ug/min
0.54
123
203
159
291
3.18
34.18
5.3
5.3
39.17
40.32
ug/min
0.09
119
212
93
225
4.10
34.05
5.5
4.4
44.80
41.55
ug/min
0.13
66
164
126
382
3.30
33.72
6.2
5.3
42.35
40.72
ug/min
0.11
102
291
159
295
3.14
33.47
5.3
5.2
39.17
41.87
ug/min
0.24
119
216
91
225
4.05
32.88
5.1
5.6
63.15
42.35
ug/min
1.71
75
170
199
372
2.75
32.23
6.8
4.5
46.96
44.63
ug/min
0.18
163
277
101
280
3.61
31.08
7.2
5.4
45.52
43.78
ug/min
0.11
83
213
182
431
2.71
30.79
5.6
5.2
40.66
45.34
ug/min
0.51
142
333
181
384
2.76
30.68
5.5
5.3
45.25
39.27
ug/min
0.63
142
278
49
76
6.49
30.20
7.2
6.3
41.90
44.42
ug/min
0.10
42
54
96
205
3.82
30.18
5.6
6.0
43.54
52.03
ug/min
0.64
76
167
169
290
2.92
30.11
5.6
4.8
40.20
46.54
ug/min
0.58
130
219
169
290
2.92
30.11
5.6
4.8
40.20
46.54
ug/min
0.58
130
219
127
297
3.17
29.45
5.8
4.9
49.51
40.32
ug/min
0.91
111
216
177
319
2.78
29.03
5.7
5.1
40.99
43.36
ug/min
0.18
127
243
96
190
3.76
28.71
6.7
4.8
53.67
44.39
ug/min
0.60
83
145
196
426
2.56
28.64
6.0
5.0
41.69
46.80
ug/min
0.57
153
329
102
253
3.48
28.56
5.6
5.0
56.07
41.65
ug/min
1.25
89
194
33
34
9.78
28.54
5.5
5.1
47.25
42.52
ug/min
0.16
28
27
147
391
2.84
28.39
5.5
5.5
42.78
48.36
ug/min
0.46
117
304
112
265
3.32
28.39
5.3
6.0
54.70
48.29
ug/min
0.37
99
215
150
298
2.91
27.99
5.2
5.2
39.46
42.06
ug/min
0.22
112
216
33
35
9.50
27.95
5.5
5.0
47.25
42.52
ug/min
0.16
28
27
42
22
10.71
27.83
4.3
4.8
43.71
15.23
ug/min
2.11
28
13
145
311
2.87
26.98
6.6
5.1
42.40
48.67
ug/min
0.53
121
243
75
189
3.97
26.40
7.1
5.7
40.71
39.28
ug/min
0.08
63
127
93
271
3.41
26.28
4.8
5.8
53.81
42.61
ug/min
0.84
70
220
111
184
3.40
26.18
5.9
5.1
33.56
38.81
ug/min
0.44
82
126
151
394
2.69
25.93
5.6
5.5
47.52
45.42
ug/min
0.15
124
305
75
169
4.00
25.90
5.0
6.2
54.64
37.66
ug/min
1.23
66
134
40
22
10.21
25.85
4.4
4.8
34.04
15.23
ug/min
1.58
26
13
40
22
10.21
25.85
4.4
4.8
34.04
15.23
ug/min
1.58
26
13
74
168
4.02
25.81
8.2
4.9
49.41
47.23
ug/min
0.10
66
141
75
173
3.93
25.41
8.2
5.0
49.22
46.25
ug/min
0.14
67
146
41
31
8.35
25.08
5.9
4.4
43.83
38.35
ug/min
0.18
35
20
78
186
3.78
24.97
8.1
4.8
49.13
48.15
ug/min
0.04
70
156
76
205
3.72
24.49
6.8
5.4
50.56
38.38
ug/min
0.79
63
149
90
160
3.61
24.25
5.3
4.5
43.63
32.32
ug/min
1.06
72
97
52
104
4.90
23.74
5.7
5.4
29.18
47.81
ug/min
1.23
39
74
62
141
4.24
23.67
6.5
5.0
32.54
47.51
ug/min
1.01
48
96
79
109
4.07
23.59
6.0
5.1
48.78
40.79
ug/min
0.44
72
82
98
305
3.10
23.57
6.7
5.4
61.67
40.91
ug/min
1.93
86
244
66
147
4.01
22.78
6.2
5.7
56.43
43.66
ug/min
0.59
60
112
72
197
3.67
22.75
5.8
5.3
34.42
41.05
ug/min
0.54
55
151
135
375
2.63
22.50
6.5
4.9
38.36
47.06
ug/min
0.92
100
285
65
167
3.90
22.46
6.6
5.8
59.47
45.05
ug/min
0.80
58
131
40
23
8.76
22.11
5.4
4.7
39.30
37.43
ug/min
0.03
25
14
119
315
2.77
22.00
6.4
5.3
51.83
46.33
ug/min
0.37
104
249
37
62
6.00
21.19
7.0
6.1
41.38
52.41
ug/min
0.38
26
49
130
294
2.66
21.05
5.7
5.5
52.62
40.77
ug/min
1.31
106
232
60
155
3.88
20.60
6.9
5.7
60.28
44.98
ug/min
0.80
54
122
60
155
3.88
20.60
6.9
5.7
60.28
45.48
ug/min
0.76
54
122
50
105
4.53
20.55
5.7
5.6
60.30
48.56
ug/min
0.38
44
77
82
258
3.15
20.50
6.8
5.3
39.56
40.52
ug/min
0.06
68
173
144
503
2.39
20.47
5.8
5.2
41.58
45.49
ug/min
0.36
113
384
139
396
2.46
20.11
6.0
5.3
52.49
44.53
ug/min
0.63
118
313
95
333
2.86
20.07
4.7
5.6
62.98
38.31
ug/min
1.94
81
244
114
323
2.68
20.06
6.0
5.3
51.66
44.08
ug/min
0.51
96
257
98
347
2.80
19.95
5.1
5.5
60.75
40.80
ug/min
1.78
79
259
98
347
2.80
19.95
5.1
5.5
60.75
40.80
ug/min
1.78
79
259
75
155
3.47
19.88
4.9
5.1
55.29
44.42
ug/min
0.46
51
114
172
457
2.26
19.84
6.2
4.9
42.02
46.13
ug/min
0.33
131
351
149
303
2.47
19.75
6.2
4.6
40.16
45.49
ug/min
0.46
109
228
98
162
3.11
19.66
4.6
5.0
47.16
44.83
ug/min
0.10
61
120
77
241
3.14
19.10
5.1
5.4
47.40
45.09
ug/min
0.12
62
188
150
511
2.29
19.01
7.0
4.9
40.55
45.88
ug/min
0.59
118
390
76
241
3.15
18.99
6.7
5.5
56.94
43.87
ug/min
0.85
68
189
29
43
6.79
18.68
3.9
6.3
38.43
58.44
ug/min
0.62
20
34
33
56
5.92
18.67
5.9
4.4
45.88
38.16
ug/min
0.23
24
36
114
392
2.53
18.52
4.2
5.6
43.83
46.17
ug/min
0.17
88
309
160
480
2.23
18.36
6.3
5.1
52.97
41.98
ug/min
1.32
133
363
72
172
3.29
18.21
6.0
5.4
46.92
53.43
ug/min
0.40
65
146
159
425
2.24
18.10
5.9
4.9
34.99
49.17
ug/min
2.31
126
326
171
393
2.21
17.88
5.9
4.9
38.77
47.01
ug/min
0.85
136
298
105
235
2.72
17.85
6.6
4.7
47.67
44.00
ug/min
0.26
91
180
115
315
2.54
17.85
5.7
5.3
32.32
47.73
ug/min
3.21
92
236
70
221
3.17
17.80
8.2
4.7
40.88
42.88
ug/min
0.11
60
171
82
218
2.96
17.50
5.3
5.3
40.45
43.98
ug/min
0.19
62
171
161
507
2.16
17.33
5.9
5.2
39.95
46.34
ug/min
0.75
127
388
106
193
2.75
17.32
6.1
4.9
47.66
43.47
ug/min
0.23
80
148
106
193
2.75
17.32
6.1
4.9
47.66
43.47
ug/min
0.23
80
148
82
129
3.19
17.01
5.6
4.7
29.43
43.20
ug/min
1.09
60
75
118
288
2.49
16.99
5.1
5.9
52.97
36.74
ug/min
1.63
97
220
58
168
3.46
16.93
4.3
6.5
64.49
49.54
ug/min
0.71
41
142
76
164
3.12
16.91
6.5
4.8
56.40
38.49
ug/min
1.24
68
110
138
340
2.32
16.83
5.4
5.5
45.23
42.92
ug/min
0.15
103
260
33
62
5.35
16.81
6.5
6.3
65.52
55.12
ug/min
0.26
27
48
53
146
3.64
16.69
6.3
6.1
46.05
44.94
ug/min
0.04
41
112
82
279
2.81
16.65
5.1
5.4
45.44
44.43
ug/min
0.05
66
221
36
74
4.88
16.58
4.7
5.8
40.96
40.02
ug/min
0.02
26
56
105
421
2.46
16.48
5.8
5.5
55.39
42.61
ug/min
0.94
89
323
85
313
2.72
16.47
6.7
5.6
62.52
46.30
ug/min
1.00
69
254
72
185
3.08
16.42
6.3
5.4
53.48
53.17
ug/min
0.01
66
156
48
125
3.85
16.38
4.4
6.1
44.51
43.23
ug/min
0.05
41
93
73
110
3.33
16.17
6.4
4.3
51.69
29.86
ug/min
1.47
51
74
143
325
2.27
16.16
5.7
5.5
44.42
38.91
ug/min
0.48
101
251
49
131
3.75
16.12
6.4
5.7
55.18
43.75
ug/min
0.54
44
97
49
131
3.75
16.12
6.9
5.6
70.10
47.29
ug/min
0.95
40
101
43
106
4.07
15.82
5.8
5.9
69.44
46.89
ug/min
0.78
36
77
103
195
2.65
15.73
6.1
4.8
47.89
43.48
ug/min
0.24
79
149
103
195
2.65
15.73
6.3
4.8
47.21
43.48
ug/min
0.20
78
149
95
236
2.64
15.73
4.8
4.9
49.64
37.97
ug/min
1.10
70
169
50
138
3.63
15.72
8.8
5.2
39.12
42.07
ug/min
0.15
42
94
75
183
2.96
15.64
4.9
4.8
55.29
41.99
ug/min
0.63
51
140
53
149
3.48
15.55
5.3
5.1
45.77
43.09
ug/min
0.11
43
117
52
142
3.53
15.53
4.9
5.7
47.96
51.78
ug/min
0.16
46
119
52
142
3.53
15.53
4.9
5.7
47.96
51.78
ug/min
0.16
46
119
52
142
3.53
15.50
4.9
5.7
47.96
51.78
ug/min
0.16
46
119
99
192
2.66
15.42
4.5
4.8
46.50
43.19
ug/min
0.15
62
147
52
143
3.51
15.38
4.9
5.8
47.96
51.58
ug/min
0.15
46
120
52
143
3.51
15.38
4.9
5.8
47.96
51.58
ug/min
0.15
46
120
56
169
3.32
15.37
4.3
6.5
64.83
49.10
ug/min
0.75
40
145
84
162
2.87
15.30
4.9
5.0
49.07
44.83
ug/min
0.16
54
120
111
286
2.42
15.17
6.3
5.2
50.14
48.89
ug/min
0.07
92
231
76
173
2.92
15.10
6.8
4.9
39.51
46.73
ug/min
0.56
68
134
33
69
4.80
14.93
4.9
6.6
39.39
46.43
ug/min
0.27
23
55
103
427
2.36
14.86
5.8
5.2
36.20
45.65
ug/min
0.93
80
327
138
467
2.13
14.70
5.5
5.4
49.31
44.14
ug/min
0.36
111
359
145
336
2.16
14.54
5.2
5.2
43.92
43.87
ug/min
0.00
108
261
67
191
2.95
14.47
4.5
4.7
68.41
33.23
ug/min
3.44
59
137
33
71
4.67
14.43
6.1
6.0
48.42
52.49
ug/min
0.12
28
54
66
152
3.04
14.28
5.4
4.8
43.27
45.81
ug/min
0.13
60
118
158
458
2.04
14.25
5.3
5.5
49.31
41.11
ug/min
0.85
129
347
87
350
2.49
14.16
5.8
5.4
38.57
44.10
ug/min
0.39
69
267
37
89
4.17
14.09
6.4
6.2
53.53
49.49
ug/min
0.15
32
70
37
89
4.17
14.09
6.4
5.4
56.72
49.72
ug/min
0.26
32
68
132
357
2.17
13.97
4.9
5.4
45.52
40.55
ug/min
0.37
100
266
58
190
3.05
13.90
5.1
5.6
50.56
43.02
ug/min
0.39
48
147
94
193
2.56
13.75
4.7
4.9
46.46
43.47
ug/min
0.13
59
148
116
265
2.30
13.58
6.0
5.2
44.13
40.78
ug/min
0.18
84
192
137
367
2.12
13.57
5.8
5.2
44.58
43.65
ug/min
0.06
105
269
92
390
2.36
13.39
5.8
5.4
48.62
42.71
ug/min
0.31
76
304
144
391
2.07
13.37
5.6
5.4
44.50
47.27
ug/min
0.17
115
293
100
206
2.46
13.32
5.1
5.7
48.84
39.83
ug/min
0.59
68
152
81
326
2.49
13.17
5.7
5.5
34.48
44.67
ug/min
1.18
60
244
79
303
2.52
13.13
6.1
5.0
39.38
45.50
ug/min
0.52
64
235
109
455
2.19
13.06
4.8
5.6
58.39
39.46
ug/min
1.54
92
341
104
441
2.22
12.99
4.8
5.6
60.10
38.29
ug/min
1.85
89
331
121
461
2.12
12.98
5.8
5.1
56.31
42.01
ug/min
1.48
99
347
41
113
3.64
12.97
5.9
5.6
53.86
42.43
ug/min
0.54
35
82
104
442
2.21
12.88
4.8
5.6
60.10
38.19
ug/min
1.86
89
332
152
425
1.99
12.80
6.2
5.1
47.22
43.87
ug/min
0.24
108
326
162
498
1.93
12.60
5.7
5.2
40.67
46.43
ug/min
0.55
123
386
63
230
2.74
12.52
6.9
5.4
44.44
42.30
ug/min
0.10
54
175
46
140
3.28
12.46
4.9
5.9
57.50
46.43
ug/min
0.60
40
117
51
167
3.06
12.32
5.4
5.1
45.90
46.99
ug/min
0.04
41
123
21
35
6.03
12.12
3.8
8.7
43.93
41.60
ug/min
0.06
14
28
54
145
3.02
12.09
5.5
6.4
49.33
60.78
ug/min
0.51
48
121
140
446
1.98
12.05
5.4
5.4
52.05
42.92
ug/min
0.83
115
347
63
235
2.69
12.03
5.0
5.9
47.70
43.59
ug/min
0.27
50
185
46
144
3.20
11.99
5.2
5.5
44.76
39.76
ug/min
0.24
38
110
144
396
1.98
11.87
6.4
5.0
53.51
39.31
ug/min
1.43
111
301
67
254
2.59
11.87
6.7
5.3
54.26
43.55
ug/min
0.52
57
185
136
336
2.03
11.79
5.6
5.2
48.77
43.87
ug/min
0.33
103
261
141
447
1.96
11.76
4.9
5.6
50.65
43.77
ug/min
0.64
121
340
57
204
2.79
11.67
5.7
5.3
46.39
38.52
ug/min
0.40
41
135
84
346
2.31
11.63
6.4
5.4
49.89
43.85
ug/min
0.32
72
259
39
112
3.48
11.58
6.6
5.3
44.61
41.83
ug/min
0.12
31
74
84
192
2.45
11.53
4.9
4.8
49.07
43.19
ug/min
0.24
54
147
38
108
3.53
11.53
4.8
6.4
45.32
43.50
ug/min
0.07
28
80
136
435
1.97
11.51
5.2
5.5
41.63
44.88
ug/min
0.23
98
349
38
108
3.53
11.51
5.9
6.1
47.79
42.30
ug/min
0.23
29
77
66
256
2.56
11.45
5.8
5.3
44.26
41.36
ug/min
0.14
50
175
70
243
2.51
11.32
5.1
5.8
62.93
47.34
ug/min
0.87
61
196
87
230
2.35
11.32
5.8
5.5
53.10
47.02
ug/min
0.31
79
187
153
453
1.89
11.24
5.6
5.2
46.01
42.85
ug/min
0.23
121
343
28
65
4.32
11.20
4.0
7.1
35.37
48.02
ug/min
0.57
21
49
75
199
2.49
11.19
5.0
5.3
39.35
49.19
ug/min
0.86
68
154
123
387
2.02
11.18
5.5
5.5
52.49
42.22
ug/min
0.82
93
301
26
57
4.58
11.16
4.6
5.1
46.05
54.38
ug/min
0.21
20
44
25
48
4.81
11.08
7.0
5.3
23.99
50.42
ug/min
1.08
18
30
23
27
8.58
11.01
8.5
5.6
46.00
64.77
ug/min
0.57
23
22
77
297
2.35
10.94
5.0
5.6
43.41
48.28
ug/min
0.25
58
240
83
171
2.43
10.92
7.1
4.4
47.55
39.54
ug/min
0.47
63
119
24
51
4.72
10.69
4.6
4.9
50.00
58.39
ug/min
0.16
19
41
43
140
3.08
10.55
5.9
5.7
57.66
40.03
ug/min
0.53
32
103
51
183
2.79
10.54
7.1
5.7
62.48
45.67
ug/min
0.61
41
147
109
258
2.12
10.53
6.9
4.4
42.85
39.91
ug/min
0.17
82
188
50
181
2.77
10.17
6.2
5.6
54.21
39.84
ug/min
0.80
42
130
37
110
3.31
10.17
6.8
4.9
28.57
45.21
ug/min
1.20
30
80
83
346
2.19
10.12
6.9
5.3
46.79
43.87
ug/min
0.19
71
266
35
103
3.41
10.11
5.6
5.1
38.42
38.16
ug/min
0.01
26
72
15
9
16.80
9.87
4.3
4.6
83.20
41.56
ug/min
—
15
9
26
63
4.14
9.87
5.0
6.8
34.63
55.57
ug/min
1.06
19
46
20
39
5.13
9.79
4.0
5.0
45.57
52.58
ug/min
0.11
14
31
136
441
1.87
9.79
5.1
5.4
41.03
44.58
ug/min
0.26
97
353
130
461
1.87
9.71
6.4
5.1
47.58
42.00
ug/min
0.37
102
357
36
111
3.25
9.68
6.2
5.8
58.85
44.64
ug/min
0.31
26
80
77
351
2.18
9.46
5.9
5.5
33.42
43.64
ug/min
0.88
62
259
48
177
2.72
9.46
4.8
5.8
80.02
39.74
ug/min
2.04
40
131
23
52
4.41
9.45
5.4
6.6
27.11
26.66
ug/min
0.02
17
31
129
341
1.90
9.33
5.2
5.5
37.16
42.92
ug/min
0.50
91
260
58
196
2.47
9.13
5.5
5.0
38.35
43.92
ug/min
0.36
48
155
55
222
2.48
9.06
5.6
5.6
35.24
40.59
ug/min
0.41
41
161
14
9
15.67
9.03
4.1
4.6
78.57
41.56
ug/min
—
14
9
42
148
2.84
9.02
6.1
5.8
36.39
40.15
ug/min
0.21
33
109
31
91
3.41
9.01
4.5
5.2
50.31
52.03
ug/min
0.06
26
73
129
397
1.85
8.95
5.4
5.5
48.29
43.34
ug/min
0.39
96
310
47
176
2.66
8.94
5.4
5.2
53.62
41.98
ug/min
0.57
34
142
36
117
3.08
8.91
6.2
5.8
58.85
45.46
ug/min
0.29
26
86
110
338
1.94
8.86
5.7
5.2
41.83
46.55
ug/min
0.30
85
252
101
474
1.92
8.60
5.9
5.1
50.07
42.79
ug/min
0.63
83
356
113
320
1.91
8.55
5.2
5.5
48.21
39.33
ug/min
0.70
78
247
27
75
3.61
8.53
4.9
5.2
49.86
55.34
ug/min
0.19
22
65
74
227
2.19
8.43
7.4
5.6
46.00
42.33
ug/min
0.19
69
170
149
429
1.74
8.30
5.7
5.2
39.70
46.21
ug/min
0.63
111
333
45
172
2.60
8.21
6.1
5.4
42.54
39.88
ug/min
0.13
35
114
36
127
2.84
7.77
6.3
5.9
62.00
49.91
ug/min
0.52
31
102
42
161
2.61
7.75
6.1
5.7
36.39
40.18
ug/min
0.22
33
115
82
337
1.99
7.69
6.0
5.2
38.17
43.63
ug/min
0.35
62
244
51
148
2.44
7.58
5.3
4.8
40.54
45.34
ug/min
0.29
46
114
52
188
2.37
7.57
3.5
5.5
80.71
39.62
ug/min
2.40
45
158
40
151
2.64
7.53
7.1
4.6
19.97
35.13
ug/min
1.92
31
95
35
122
2.84
7.53
5.8
5.7
52.40
45.96
ug/min
0.16
27
91
61
281
2.17
7.50
5.8
5.4
61.25
38.38
ug/min
1.27
48
213
58
262
2.21
7.47
5.6
5.4
53.42
40.44
ug/min
0.59
47
188
115
438
1.78
7.43
5.0
5.3
48.26
43.90
ug/min
0.30
87
340
19
39
4.34
7.42
4.0
5.9
63.40
18.85
ug/min
0.94
12
23
37
136
2.73
7.41
6.8
5.4
28.57
43.44
ug/min
1.21
30
104
25
73
3.44
7.38
5.8
6.2
45.44
44.57
ug/min
0.03
20
58
55
228
2.25
7.30
6.2
5.6
45.12
42.80
ug/min
0.10
45
174
23
64
3.61
7.29
6.0
6.4
44.93
46.29
ug/min
0.04
18
51
20
51
3.93
7.15
5.2
7.6
24.29
38.94
ug/min
0.67
14
35
35
110
2.76
6.99
5.6
4.8
29.20
49.51
ug/min
1.21
24
74
141
459
1.67
6.97
5.3
5.5
46.08
43.16
ug/min
0.21
102
361
73
272
2.00
6.92
4.5
5.6
35.47
41.78
ug/min
0.57
59
195
22
62
3.56
6.85
4.6
5.7
69.29
42.60
ug/min
0.57
17
50
75
385
1.94
6.82
4.0
5.5
48.85
42.87
ug/min
0.35
60
289
36
137
2.63
6.76
5.3
5.9
31.02
42.48
ug/min
0.86
26
98
17
28
6.10
6.76
3.5
8.7
44.64
47.34
ug/min
0.05
11
23
58
247
2.13
6.75
5.5
4.8
57.16
43.70
ug/min
0.84
45
188
41
167
2.46
6.73
6.1
5.7
36.16
41.63
ug/min
0.34
31
123
50
223
2.25
6.70
7.7
5.1
36.90
43.27
ug/min
0.43
42
170
109
309
1.78
6.69
5.5
5.2
45.60
42.20
ug/min
0.21
81
224
62
299
2.06
6.68
5.1
5.7
39.64
42.07
ug/min
0.09
39
232
76
399
1.91
6.60
5.7
5.4
56.65
41.09
ug/min
0.96
60
312
18
45
4.01
6.60
5.9
6.6
26.31
26.61
ug/min
0.02
13
27
88
405
1.83
6.59
4.8
5.6
53.50
41.44
ug/min
0.81
70
313
136
471
1.65
6.56
5.6
5.4
51.63
42.95
ug/min
0.76
112
364
79
233
1.95
6.52
5.3
5.1
38.46
31.10
ug/min
0.63
56
161
50
226
2.22
6.50
3.7
5.8
60.33
40.98
ug/min
0.68
30
182
53
216
2.18
6.45
6.5
5.1
37.26
44.47
ug/min
0.33
38
149
52
240
2.17
6.43
6.2
5.3
48.13
42.04
ug/min
0.24
46
181
34
101
2.70
6.41
5.9
6.6
73.00
43.36
ug/min
0.98
28
83
48
214
2.24
6.41
5.1
5.9
63.24
52.12
ug/min
0.39
41
182
67
308
1.98
6.40
7.7
4.9
30.27
44.91
ug/min
1.95
59
229
69
336
1.94
6.31
5.9
5.4
51.92
45.31
ug/min
0.34
59
267
6
0
+∞
6.30
7.0
0.0
52.50
—
ug/min
—
6
0
6
0
+∞
6.26
5.5
0.0
88.17
—
ug/min
—
6
0
34
131
2.60
6.26
5.2
5.5
64.67
47.90
ug/min
0.57
27
107
73
294
1.92
6.21
5.3
5.1
46.82
43.57
ug/min
0.16
58
223
90
268
1.83
6.20
6.4
5.9
45.06
41.53
ug/min
0.16
71
221
58
255
2.06
6.20
6.4
5.7
47.90
43.07
ug/min
0.25
50
195
109
371
1.71
6.07
5.4
5.5
47.40
40.14
ug/min
0.59
95
269
62
296
1.99
6.05
4.4
5.6
52.47
47.22
ug/min
0.31
53
240
117
454
1.67
6.04
6.0
5.3
39.19
45.55
ug/min
0.57
94
349
17
33
5.18
6.00
5.6
8.2
32.82
44.45
ug/min
0.38
11
26
17
33
5.18
6.00
5.6
8.2
32.82
44.45
ug/min
0.38
11
26
60
198
2.05
5.94
7.7
5.6
42.18
43.72
ug/min
0.08
55
148
115
449
1.66
5.89
4.9
5.5
47.58
42.86
ug/min
0.36
84
345
22
69
3.19
5.86
6.0
6.3
55.41
39.96
ug/min
0.44
16
52
95
364
1.74
5.79
6.0
5.5
44.47
45.86
ug/min
0.08
78
289
58
287
1.99
5.74
7.3
5.0
35.43
43.64
ug/min
0.69
46
221
110
432
1.67
5.74
5.0
5.5
50.55
40.05
ug/min
1.07
83
331
66
330
1.90
5.73
6.0
5.5
52.30
44.85
ug/min
0.38
56
263
77
417
1.80
5.65
4.7
5.5
50.49
43.88
ug/min
0.29
53
326
77
417
1.80
5.65
4.7
5.5
50.49
43.88
ug/min
0.29
53
326
65
163
2.00
5.64
6.5
5.1
49.85
44.45
ug/min
0.22
50
127
106
416
1.68
5.64
5.0
5.5
48.70
40.73
ug/min
0.74
79
319
17
31
4.83
5.58
6.3
5.9
68.92
25.26
ug/min
0.96
12
22
45
178
2.19
5.58
5.8
5.2
28.08
42.59
ug/min
1.21
33
120
142
483
1.57
5.56
5.5
5.3
50.81
42.47
ug/min
0.82
110
368
100
398
1.69
5.51
4.8
5.5
49.05
39.61
ug/min
0.95
74
304
107
373
1.67
5.50
5.4
5.5
47.04
40.32
ug/min
0.52
93
271
17
37
4.61
5.47
5.6
8.0
32.82
42.92
ug/min
0.32
11
27
63
297
1.91
5.47
4.6
4.5
42.80
31.13
ug/min
0.93
50
201
17
37
4.61
5.47
3.7
4.9
62.76
57.87
ug/min
0.07
17
30
99
390
1.69
5.42
5.9
5.5
43.79
46.35
ug/min
0.16
80
308
50
219
2.06
5.40
5.1
5.8
47.04
49.64
ug/min
0.13
45
188
39
160
2.27
5.39
5.2
4.9
32.36
46.68
ug/min
0.73
27
109
16
43
3.73
5.36
5.3
5.9
28.56
60.59
ug/min
—
9
37
48
202
2.09
5.33
7.3
5.5
42.63
40.51
ug/min
0.10
41
150
42
169
2.20
5.33
4.8
5.9
56.48
43.30
ug/min
0.51
37
135
104
364
1.67
5.30
5.4
5.6
48.42
40.65
ug/min
0.55
90
267
29
113
2.57
5.28
7.0
6.0
49.14
48.95
ug/min
0.00
22
88
114
486
1.61
5.27
5.1
5.5
47.49
43.48
ug/min
0.23
86
371
136
522
1.55
5.17
5.5
5.3
49.94
42.66
ug/min
0.63
113
394
38
92
2.36
5.11
5.0
6.0
41.24
27.57
ug/min
0.45
21
70
42
197
2.14
5.07
4.6
5.7
69.64
40.65
ug/min
1.22
28
142
43
195
2.12
5.07
5.5
5.4
34.87
37.35
ug/min
0.09
31
130
29
114
2.50
4.98
6.1
4.9
39.09
57.10
ug/min
0.98
23
100
89
366
1.69
4.96
6.3
5.5
56.32
45.98
ug/min
0.64
79
292
126
408
1.57
4.93
5.3
5.4
37.98
44.26
ug/min
0.58
88
317
111
482
1.59
4.88
5.2
5.5
48.35
43.48
ug/min
0.28
83
368
27
106
2.55
4.86
6.3
5.3
43.09
49.27
ug/min
0.20
22
83
27
106
2.55
4.86
6.3
5.3
43.09
49.27
ug/min
0.20
22
83
122
531
1.55
4.85
4.9
5.5
53.43
42.53
ug/min
1.08
94
413
95
339
1.66
4.84
4.9
5.5
46.38
43.03
ug/min
0.15
66
259
31
132
2.35
4.72
6.0
5.4
42.65
38.39
ug/min
0.17
20
101
107
405
1.60
4.70
4.6
5.6
47.70
42.20
ug/min
0.36
80
310
104
415
1.60
4.70
5.3
5.5
45.28
41.81
ug/min
0.19
81
313
45
184
2.03
4.67
5.4
5.5
43.47
53.75
ug/min
0.44
38
133
46
205
2.01
4.66
6.9
4.7
18.47
36.14
ug/min
3.80
36
137
54
208
1.91
4.61
5.6
5.0
34.94
32.59
ug/min
0.15
34
146
31
135
2.30
4.50
4.7
5.9
68.21
42.60
ug/min
0.95
24
110
41
194
2.05
4.48
4.9
5.8
37.99
43.08
ug/min
0.14
28
149
81
301
1.68
4.38
5.3
5.3
56.14
39.87
ug/min
0.87
65
218
120
400
1.54
4.38
5.1
5.4
48.05
43.72
ug/min
0.31
81
312
33
150
2.20
4.35
5.5
4.9
23.79
34.82
ug/min
0.99
19
112
12
23
5.02
4.28
7.0
6.7
37.00
19.29
ug/min
0.71
12
15
111
371
1.55
4.18
5.4
5.5
41.39
44.63
ug/min
0.24
83
291
24
44
2.74
4.16
7.3
3.7
35.79
44.87
ug/min
0.22
16
25
122
522
1.50
4.16
6.1
5.3
48.92
42.88
ug/min
0.41
96
400
42
186
1.98
4.15
6.4
5.5
45.29
40.80
ug/min
0.21
35
138
71
414
1.67
4.13
5.1
5.7
64.15
45.11
ug/min
1.36
60
329
51
205
1.87
4.13
6.0
4.9
39.58
30.08
ug/min
0.68
36
138
97
361
1.57
4.07
5.4
5.6
51.09
40.73
ug/min
0.77
84
266
77
326
1.65
4.06
3.9
6.2
70.77
40.33
ug/min
3.30
71
262
30
63
2.39
4.04
6.9
3.8
52.04
31.33
ug/min
0.89
24
46
25
105
2.38
3.97
4.6
5.8
77.94
44.20
ug/min
0.77
17
72
121
523
1.48
3.92
6.0
5.3
48.92
42.88
ug/min
0.41
96
400
15
31
3.31
3.87
5.3
3.8
31.56
34.60
ug/min
—
9
18
125
442
1.48
3.87
4.9
5.6
46.09
44.32
ug/min
0.09
87
354
41
212
1.93
3.87
6.1
5.4
38.44
38.29
ug/min
0.01
34
140
39
194
1.97
3.86
5.6
5.4
26.61
38.13
ug/min
0.86
28
129
96
362
1.55
3.84
5.4
5.6
51.58
40.73
ug/min
0.81
83
266
39
186
1.95
3.75
4.9
5.8
66.67
51.62
ug/min
0.51
33
162
38
195
1.95
3.70
5.4
6.0
58.53
51.82
ug/min
0.18
30
154
40
210
1.91
3.65
5.5
6.0
56.41
50.43
ug/min
0.17
32
168
115
500
1.47
3.61
5.3
5.5
54.25
42.02
ug/min
1.19
89
391
113
514
1.47
3.61
6.1
5.3
51.15
42.77
ug/min
0.55
89
394
37
190
1.95
3.61
5.4
5.3
57.47
36.08
ug/min
1.67
32
131
45
247
1.82
3.59
4.9
5.5
52.21
36.38
ug/min
0.63
29
176
30
77
2.21
3.56
5.8
5.7
50.56
30.02
ug/min
0.69
25
60
20
78
2.50
3.52
4.1
4.9
35.57
33.25
ug/min
—
7
51
138
512
1.42
3.52
4.4
5.6
43.94
45.07
ug/min
0.07
96
403
90
392
1.53
3.47
5.4
5.5
41.79
40.87
ug/min
0.07
78
296
92
353
1.53
3.46
5.5
5.6
48.57
40.74
ug/min
0.53
79
262
37
193
1.92
3.46
4.9
6.1
63.57
46.61
ug/min
0.69
30
153
15
194
0.39
3.44
5.2
6.9
58.36
41.14
ug/min
—
10
164
91
309
1.54
3.42
4.8
5.2
44.55
42.20
ug/min
0.12
66
224
42
227
1.83
3.42
4.0
5.3
47.88
42.84
ug/min
0.19
33
171
114
501
1.45
3.40
5.3
5.4
52.19
42.48
ug/min
0.94
89
391
13
38
3.42
3.30
8.6
5.3
32.38
22.00
ug/min
—
8
23
99
544
1.47
3.30
4.6
5.5
50.25
43.52
ug/min
0.35
63
431
86
386
1.52
3.28
5.3
5.5
41.43
40.59
ug/min
0.06
74
291
79
252
1.57
3.27
6.1
5.0
44.18
44.99
ug/min
0.03
59
197
54
156
1.74
3.24
6.1
5.0
47.03
42.29
ug/min
0.19
39
114
13
43
3.02
3.24
8.6
5.6
32.38
22.85
ug/min
—
8
27
37
199
1.86
3.19
5.0
6.1
60.18
44.33
ug/min
0.45
28
159
37
199
1.86
3.19
5.0
6.1
60.18
44.33
ug/min
0.45
28
159
68
307
1.59
3.18
5.9
5.4
59.55
44.13
ug/min
0.86
62
245
65
384
1.59
3.18
5.0
5.4
56.52
45.95
ug/min
0.57
54
303
11
29
3.80
3.18
5.4
7.1
40.00
42.55
ug/min
0.05
11
20
102
407
1.46
3.16
5.6
5.4
47.89
39.94
ug/min
0.61
86
296
107
434
1.45
3.16
5.7
5.4
49.67
43.19
ug/min
0.40
86
330
20
85
2.36
3.14
5.8
5.2
73.85
45.92
ug/min
0.72
20
62
66
325
1.59
3.12
5.6
5.5
36.33
47.04
ug/min
1.17
48
270
121
428
1.42
3.07
5.3
5.4
48.97
41.62
ug/min
0.59
84
326
63
284
1.60
3.06
5.6
5.5
62.49
44.35
ug/min
0.97
57
231
15
56
2.68
3.05
4.1
5.9
39.60
50.91
ug/min
—
10
45
93
427
1.47
3.05
5.5
5.4
49.97
43.85
ug/min
0.33
70
335
64
271
1.60
3.03
5.3
5.4
55.94
42.95
ug/min
0.75
54
205
35
189
1.85
2.99
4.5
5.6
48.62
36.52
ug/min
0.38
21
134
5
5
10.08
2.98
8.4
10.8
42.20
34.80
ug/min
—
5
5
60
255
1.61
2.96
5.6
5.1
26.90
34.89
ug/min
0.87
42
178
17
69
2.47
2.95
5.9
5.6
81.00
41.60
ug/min
0.96
17
50
30
155
1.94
2.93
5.5
5.7
45.41
41.84
ug/min
0.09
22
110
12
37
3.25
2.93
5.0
6.2
78.75
45.89
ug/min
0.58
12
30
109
395
1.43
2.92
5.8
5.1
46.88
43.11
ug/min
0.25
83
301
17
194
0.44
2.92
5.6
6.9
40.80
41.14
ug/min
0.01
12
164
66
209
1.59
2.91
6.2
5.5
49.82
51.42
ug/min
0.07
51
173
12
37
3.20
2.88
3.9
5.9
40.20
37.19
ug/min
—
5
26
10
27
3.71
2.87
3.7
4.2
15.60
19.24
ug/min
—
5
17
95
483
1.44
2.87
6.7
5.0
41.69
45.32
ug/min
0.24
72
372
69
403
1.53
2.87
5.4
5.5
50.63
44.91
ug/min
0.35
54
323
72
475
1.50
2.79
5.0
5.5
55.55
41.56
ug/min
0.76
49
364
8
18
4.45
2.79
5.8
6.1
71.13
53.46
ug/min
—
8
13
14
53
2.64
2.79
6.9
4.7
64.57
61.45
ug/min
0.04
14
44
33
92
1.92
2.77
5.7
6.0
30.62
27.57
ug/min
0.14
13
70
39
223
1.74
2.77
5.6
5.5
62.42
43.22
ug/min
0.68
33
180
39
223
1.74
2.77
5.6
5.5
62.42
43.22
ug/min
0.68
33
180
39
223
1.74
2.77
5.6
5.5
62.42
43.22
ug/min
0.68
33
180
67
276
1.54
2.74
4.9
5.9
52.15
37.76
ug/min
1.08
55
209
80
517
1.46
2.72
5.7
5.3
55.90
42.23
ug/min
0.75
63
396
23
112
2.06
2.66
6.8
6.2
49.83
47.80
ug/min
0.04
18
85
12
40
2.96
2.64
3.9
5.7
40.20
37.57
ug/min
—
5
28
51
159
1.65
2.64
5.9
4.4
50.49
41.78
ug/min
0.41
41
126
97
532
1.41
2.62
5.8
5.3
58.75
43.36
ug/min
0.91
75
415
26
107
1.97
2.59
5.1
5.9
26.04
32.45
ug/min
0.44
19
66
20
91
2.15
2.57
4.1
4.8
35.57
33.97
ug/min
—
7
62
34
192
1.76
2.51
5.5
5.1
40.11
43.98
ug/min
0.15
27
155
107
388
1.38
2.44
5.2
5.6
43.40
43.30
ug/min
0.00
79
300
62
250
1.52
2.44
5.5
5.0
61.86
44.67
ug/min
0.67
49
195
20
96
2.08
2.42
4.3
5.4
56.27
47.13
ug/min
0.20
15
82
15
64
2.35
2.38
5.3
6.3
30.22
50.32
ug/min
—
9
48
14
58
2.42
2.36
5.7
5.4
31.71
21.10
ug/min
—
7
37
23
118
1.95
2.34
4.8
5.8
38.07
33.34
ug/min
0.18
15
78
77
271
1.45
2.34
6.4
5.5
41.47
40.58
ug/min
0.05
60
206
111
417
1.36
2.32
5.2
5.5
50.92
42.09
ug/min
0.58
85
333
25
102
1.91
2.31
2.8
5.4
54.63
37.37
ug/min
0.83
19
81
15
65
2.31
2.31
5.7
5.3
61.73
42.98
ug/min
0.38
15
47
20
98
2.04
2.30
7.5
5.2
54.65
53.66
ug/min
0.02
20
74
117
436
1.34
2.28
5.3
5.4
42.20
43.20
ug/min
0.06
93
332
10
34
2.95
2.28
1.6
8.9
37.00
43.11
ug/min
—
5
27
13
53
2.46
2.27
4.2
5.4
33.88
58.43
ug/min
—
8
41
29
163
1.78
2.26
5.8
5.8
37.14
39.17
ug/min
0.09
21
123
44
274
1.58
2.23
4.8
5.6
57.70
43.97
ug/min
0.70
33
212
49
162
1.58
2.22
5.7
5.1
36.33
45.05
ug/min
0.67
39
129
56
273
1.51
2.21
5.6
5.5
60.20
45.16
ug/min
0.83
50
223
11
41
2.69
2.20
6.7
8.4
30.91
44.06
ug/min
0.50
11
31
50
165
1.57
2.19
6.5
5.1
44.41
45.29
ug/min
0.04
37
132
115
538
1.33
2.18
5.7
5.3
48.45
43.55
ug/min
0.31
89
417
46
270
1.56
2.17
5.9
5.2
37.97
41.50
ug/min
0.17
36
185
51
301
1.52
2.15
5.3
5.7
66.34
42.41
ug/min
1.20
38
233
66
387
1.44
2.14
7.1
5.2
53.18
47.51
ug/min
0.36
55
312
62
338
1.46
2.13
5.7
5.3
25.77
39.43
ug/min
1.75
40
247
68
432
1.43
2.11
5.6
5.4
43.76
46.22
ug/min
0.12
59
332
66
411
1.43
2.10
4.5
5.7
50.97
46.91
ug/min
0.24
60
320
69
422
1.42
2.09
4.6
5.6
50.89
46.97
ug/min
0.24
63
329
8
25
3.21
2.09
2.5
5.4
54.63
61.35
ug/min
—
8
20
87
315
1.39
2.09
5.2
5.6
37.75
42.82
ug/min
0.35
62
241
46
205
1.56
2.08
4.5
6.1
58.12
40.55
ug/min
0.53
33
170
70
472
1.41
2.07
5.1
5.5
38.05
42.70
ug/min
0.30
55
357
37
229
1.62
2.06
6.0
5.5
57.56
45.47
ug/min
0.35
27
183
17
82
2.07
2.05
4.4
5.5
32.18
35.34
ug/min
0.14
11
65
29
104
1.76
2.03
2.8
5.6
16.31
24.22
ug/min
0.67
16
62
11
44
2.50
2.00
4.8
7.2
33.36
22.93
ug/min
0.19
11
28
18
90
2.00
2.00
4.6
6.3
56.82
47.24
ug/min
0.34
11
69
55
352
1.47
1.99
7.1
5.2
51.77
48.50
ug/min
0.17
47
285
82
296
1.39
1.99
5.7
5.7
39.34
41.37
ug/min
0.11
55
229
41
145
1.59
1.97
5.9
5.7
51.14
54.90
ug/min
0.15
35
124
50
220
1.51
1.97
3.9
5.4
40.69
44.37
ug/min
0.22
39
167
107
420
1.32
1.96
5.4
5.5
43.16
42.00
ug/min
0.06
78
334
56
326
1.46
1.96
6.1
5.5
49.07
46.96
ug/min
0.07
43
271
86
554
1.35
1.94
4.9
5.4
47.95
42.92
ug/min
0.23
56
436
60
390
1.43
1.94
5.2
5.4
53.45
42.79
ug/min
0.61
51
299
30
180
1.67
1.91
4.8
5.7
38.35
38.80
ug/min
0.02
23
134
46
306
1.50
1.90
6.2
5.7
39.72
46.66
ug/min
0.35
33
240
27
85
1.77
1.90
4.6
5.6
39.14
28.67
ug/min
0.52
14
65
57
336
1.44
1.87
5.4
5.4
38.78
41.61
ug/min
0.21
45
264
21
114
1.84
1.86
6.2
5.6
28.93
40.84
ug/min
0.65
15
81
8
28
2.86
1.86
3.8
5.8
84.25
44.32
ug/min
—
8
22
39
252
1.55
1.85
5.4
5.7
47.32
45.65
ug/min
0.05
28
187
81
296
1.37
1.85
5.7
5.7
44.54
41.37
ug/min
0.15
55
229
19
100
1.90
1.85
6.5
5.2
41.33
34.26
ug/min
0.26
12
61
17
86
1.98
1.84
5.2
6.4
36.45
43.69
ug/min
0.24
11
61
31
189
1.64
1.84
5.4
5.9
63.44
44.13
ug/min
0.51
25
146
22
119
1.80
1.82
4.1
5.4
18.07
33.35
ug/min
1.06
15
70
9
35
2.58
1.80
5.8
5.6
58.00
58.07
ug/min
—
9
28
62
292
1.41
1.78
6.4
5.5
46.70
47.69
ug/min
0.04
54
235
68
420
1.37
1.75
5.7
5.3
38.92
42.22
ug/min
0.28
61
321
5
13
3.85
1.71
8.8
4.8
31.20
61.75
ug/min
—
5
8
5
13
3.85
1.71
8.8
4.8
31.20
61.75
ug/min
—
5
8
5
13
3.85
1.71
8.8
4.8
31.20
61.75
ug/min
—
5
8
8
31
2.59
1.66
6.0
5.6
55.00
60.91
ug/min
—
8
23
7
25
2.80
1.65
6.3
4.6
98.43
45.65
ug/min
—
7
17
15
76
1.98
1.64
7.8
6.6
36.47
50.02
ug/min
0.63
15
57
48
335
1.43
1.62
4.6
5.5
57.13
41.80
ug/min
0.54
36
255
29
168
1.60
1.61
4.8
5.4
39.18
40.46
ug/min
0.05
22
131
51
361
1.41
1.59
4.6
5.4
62.53
42.48
ug/min
0.73
39
278
96
568
1.29
1.58
5.8
5.3
45.44
44.58
ug/min
0.05
75
437
83
372
1.32
1.58
5.2
5.5
45.59
44.65
ug/min
0.05
61
301
22
75
1.76
1.57
3.1
5.7
32.08
25.68
ug/min
0.21
13
57
11
50
2.20
1.56
5.9
5.4
34.73
58.49
ug/min
0.92
11
39
47
166
1.46
1.56
5.8
5.1
45.61
45.49
ug/min
0.00
38
133
58
414
1.38
1.56
4.6
5.6
53.85
42.35
ug/min
0.62
47
325
30
93
1.62
1.55
6.9
5.9
50.53
27.57
ug/min
0.62
19
70
36
239
1.50
1.55
5.9
5.6
60.75
38.71
ug/min
0.69
28
182
28
176
1.59
1.54
8.5
5.8
35.35
40.15
ug/min
0.25
20
142
14
71
1.97
1.53
5.4
5.9
25.14
37.42
ug/min
—
7
49
18
100
1.80
1.52
5.2
5.8
34.64
34.26
ug/min
0.01
11
65
7
27
2.60
1.51
6.0
6.8
15.71
46.84
ug/min
—
7
19
40
273
1.46
1.50
4.7
5.7
49.16
40.77
ug/min
0.33
28
207
25
154
1.62
1.49
9.0
5.0
46.55
40.28
ug/min
0.22
20
100
13
65
2.00
1.48
6.0
4.9
41.75
44.98
ug/min
—
8
49
101
533
1.27
1.46
5.2
5.4
40.50
44.21
ug/min
0.28
74
414
11
52
2.12
1.44
4.2
6.4
21.20
50.84
ug/min
—
5
40
64
475
1.33
1.43
5.4
5.6
35.04
43.84
ug/min
0.94
50
367
60
241
1.36
1.42
6.8
5.4
48.59
42.97
ug/min
0.30
46
182
63
239
1.35
1.39
6.4
5.6
44.31
41.77
ug/min
0.14
51
185
9
41
2.20
1.37
5.7
6.0
36.78
55.63
ug/min
—
9
32
108
522
1.24
1.34
5.2
5.4
52.53
43.50
ug/min
0.58
79
411
47
436
0.73
1.34
4.7
5.5
30.81
41.88
ug/min
1.15
28
329
47
436
0.73
1.34
4.7
5.5
30.81
41.88
ug/min
1.15
28
329
59
402
1.33
1.34
4.6
5.7
55.22
47.34
ug/min
0.51
54
316
43
299
1.40
1.32
4.9
5.7
33.90
44.92
ug/min
0.75
31
241
9
124
0.50
1.31
7.1
5.5
41.33
50.21
ug/min
—
9
107
48
270
1.38
1.31
4.4
5.4
57.66
42.80
ug/min
0.68
41
204
13
62
1.91
1.30
3.8
5.5
42.57
23.97
ug/min
—
7
45
31
209
1.48
1.29
4.0
5.9
42.32
39.92
ug/min
0.07
19
165
10
48
2.09
1.27
6.6
6.0
73.70
41.97
ug/min
—
10
36
68
325
1.31
1.27
5.7
5.2
44.73
34.34
ug/min
0.62
49
232
6
25
2.40
1.24
7.3
6.2
102.33
62.45
ug/min
—
6
20
38
207
1.42
1.22
6.2
5.1
36.43
48.99
ug/min
0.93
28
176
8
37
2.16
1.21
5.6
5.9
57.63
63.03
ug/min
—
8
32
39
263
1.40
1.21
5.6
5.2
55.14
48.89
ug/min
0.19
28
220
102
438
1.23
1.19
5.6
5.3
44.58
43.79
ug/min
0.04
72
343
47
345
1.35
1.19
5.8
5.4
43.02
42.58
ug/min
0.02
36
248
6
26
2.31
1.18
5.3
5.2
19.83
63.35
ug/min
—
6
20
71
435
1.28
1.18
4.8
5.5
35.67
41.51
ug/min
0.34
53
321
38
223
1.40
1.18
6.4
5.0
42.39
42.75
ug/min
0.01
24
166
27
181
1.49
1.17
6.1
5.3
35.63
37.01
ug/min
0.05
19
126
10
50
2.00
1.16
5.3
6.1
29.00
50.96
ug/min
—
5
38
0
34
0.00
1.15
0.0
4.8
—
68.68
—
0
25
58
447
1.30
1.13
6.2
5.3
56.33
42.12
ug/min
0.77
45
343
28
191
1.47
1.13
4.4
5.5
46.81
37.76
ug/min
0.43
21
130
46
343
1.34
1.13
4.7
5.8
56.44
45.62
ug/min
0.44
36
275
39
277
1.38
1.12
5.6
5.5
53.57
46.00
ug/min
0.23
30
222
33
233
1.42
1.12
5.5
5.6
33.48
39.43
ug/min
0.39
27
175
19
291
0.64
1.12
6.0
5.4
52.71
38.80
ug/min
0.25
14
203
10
132
0.54
1.10
6.3
5.7
47.10
48.09
ug/min
—
10
114
43
212
1.36
1.09
5.0
5.4
59.13
44.45
ug/min
0.56
30
162
35
247
1.39
1.09
5.0
5.5
60.13
39.71
ug/min
0.50
24
186
118
542
1.20
1.08
4.3
5.6
48.39
44.84
ug/min
0.19
75
432
24
161
1.49
1.06
4.5
5.9
45.36
40.31
ug/min
0.12
14
122
62
369
1.28
1.06
4.7
5.6
35.31
41.03
ug/min
0.32
44
273
52
202
1.32
1.06
7.2
5.6
43.60
42.99
ug/min
0.03
43
155
35
253
1.38
1.05
4.8
5.5
74.76
46.13
ug/min
0.53
21
190
13
75
1.73
1.02
4.0
6.2
69.85
41.78
ug/min
0.75
13
60
23
156
1.48
0.98
5.1
6.1
48.19
39.54
ug/min
0.37
16
115
0
30
0.00
0.97
0.0
6.5
—
37.38
—
0
23
7
36
1.95
0.97
5.1
6.4
88.43
42.27
ug/min
—
7
28
23
153
1.47
0.95
6.5
4.9
38.87
32.51
ug/min
0.30
15
99
48
365
1.29
0.94
5.1
5.4
50.86
43.16
ug/min
0.54
37
284
11
62
1.78
0.94
5.2
5.5
46.27
43.20
ug/min
0.10
11
45
28
199
1.40
0.93
5.5
5.4
49.35
40.43
ug/min
0.33
22
137
37
277
1.34
0.93
4.6
5.8
46.10
42.01
ug/min
0.17
31
219
33
426
0.74
0.92
4.5
5.3
32.86
37.91
ug/min
0.29
21
312
116
532
1.18
0.91
4.8
5.5
44.27
44.24
ug/min
0.00
88
411
10
169
0.58
0.91
2.2
5.9
34.50
39.44
ug/min
—
10
124
48
358
1.28
0.91
5.1
5.6
40.43
44.00
ug/min
0.13
35
285
42
322
1.30
0.90
6.4
5.4
32.10
43.75
ug/min
0.92
31
248
64
257
1.25
0.89
5.8
5.3
42.65
47.36
ug/min
0.24
47
207
28
321
0.73
0.89
3.8
5.6
43.48
45.66
ug/min
0.06
23
261
44
289
1.30
0.88
5.3
5.4
35.95
41.97
ug/min
0.30
30
203
54
358
1.26
0.88
4.5
5.6
54.54
44.51
ug/min
0.63
48
279
62
388
1.24
0.87
4.7
5.5
35.31
41.69
ug/min
0.36
44
291
17
111
1.53
0.87
3.9
5.8
32.73
37.62
ug/min
0.13
11
81
6
30
2.00
0.87
4.7
5.5
51.17
55.12
ug/min
—
6
25
57
227
1.26
0.85
5.7
5.7
52.96
36.18
ug/min
0.84
38
174
25
178
1.40
0.84
6.6
5.4
33.94
39.64
ug/min
0.19
20
121
44
266
1.29
0.84
4.4
5.3
31.50
37.78
ug/min
0.37
29
190
8
102
0.56
0.84
6.9
5.1
45.38
52.38
ug/min
—
8
88
8
45
1.78
0.84
6.4
5.6
40.38
54.13
ug/min
—
8
39
6
92
0.52
0.84
6.3
5.0
18.67
55.43
ug/min
—
6
81
6
92
0.52
0.84
6.3
5.0
18.67
55.43
ug/min
—
6
81
29
213
1.36
0.84
5.3
5.4
56.35
45.16
ug/min
0.26
23
173
19
70
1.51
0.84
4.0
5.9
31.64
31.32
ug/min
0.01
11
56
10
57
1.76
0.83
5.9
5.6
34.50
50.31
ug/min
—
10
47
6
112
0.54
0.83
4.3
7.0
43.50
43.84
ug/min
—
6
87
17
71
1.53
0.82
3.1
5.7
20.00
26.66
ug/min
—
8
54
8
46
1.73
0.82
5.8
6.4
22.32
37.81
ug/min
—
8
27
40
462
0.78
0.81
4.3
5.6
38.22
40.79
ug/min
0.13
32
353
63
399
1.22
0.81
5.5
5.4
55.09
44.09
ug/min
0.57
56
313
0
25
0.00
0.79
0.0
6.9
—
22.67
—
0
15
32
399
0.77
0.76
4.4
5.2
33.20
38.37
ug/min
0.28
20
288
43
270
1.27
0.76
5.7
5.5
70.87
45.70
ug/min
1.19
38
221
15
99
1.52
0.75
4.3
6.3
62.11
44.00
ug/min
—
9
77
9
53
1.70
0.75
7.8
5.6
59.00
55.21
ug/min
—
9
42
18
124
1.45
0.75
3.6
6.0
43.73
41.69
ug/min
0.05
11
89
18
112
1.45
0.74
6.0
5.8
45.45
47.25
ug/min
0.04
13
75
22
158
1.39
0.74
5.2
5.6
38.12
40.66
ug/min
0.09
17
119
17
116
1.47
0.74
7.1
5.9
27.33
46.27
ug/min
1.32
12
83
98
558
1.16
0.73
5.2
5.4
46.13
44.64
ug/min
0.07
65
440
78
566
1.18
0.73
5.3
5.4
47.68
44.61
ug/min
0.14
57
438
9
56
1.61
0.72
7.1
6.4
67.56
47.32
ug/min
—
9
41
22
159
1.38
0.72
5.5
5.8
33.82
38.58
ug/min
0.27
17
127
104
468
1.16
0.71
6.0
5.3
42.39
47.91
ug/min
0.38
73
372
19
140
0.71
0.69
5.4
5.2
60.07
33.81
ug/min
0.51
14
101
11
64
1.60
0.69
2.6
5.3
18.80
25.45
ug/min
—
5
33
13
85
1.53
0.68
3.8
5.6
42.57
32.39
ug/min
—
7
53
59
449
1.20
0.68
4.5
5.6
52.36
45.89
ug/min
0.39
53
349
10
61
1.64
0.68
3.9
5.8
40.00
42.09
ug/min
—
5
49
11
69
1.60
0.68
5.1
5.7
39.82
41.79
ug/min
0.06
11
54
20
144
1.39
0.67
5.2
5.9
41.53
43.21
ug/min
0.04
15
108
13
70
1.53
0.67
5.6
4.7
21.80
32.65
ug/min
—
5
47
34
266
1.27
0.66
6.0
5.6
58.88
43.84
ug/min
0.40
25
204
5
28
1.79
0.66
3.0
6.2
73.60
59.52
ug/min
—
5
21
15
214
0.70
0.66
3.9
5.6
51.50
40.76
ug/min
—
8
149
15
73
1.48
0.65
5.5
5.7
74.60
29.03
ug/min
—
10
57
21
154
1.36
0.64
4.2
5.7
27.77
35.59
ug/min
0.28
15
107
61
437
0.84
0.64
4.2
5.7
50.51
47.18
ug/min
0.16
51
351
5
29
1.73
0.64
4.8
8.7
22.40
25.28
ug/min
—
5
18
23
303
0.76
0.63
3.9
5.5
47.94
42.03
ug/min
0.13
17
220
8
49
1.63
0.62
8.4
5.2
77.25
56.10
ug/min
—
8
41
39
315
1.24
0.61
4.4
5.1
42.57
39.88
ug/min
0.11
28
231
25
154
1.32
0.61
5.5
5.3
39.00
42.17
ug/min
0.06
18
98
8
50
1.60
0.61
7.0
5.7
59.38
44.68
ug/min
—
8
39
40
227
1.24
0.61
5.6
5.5
48.09
49.91
ug/min
0.06
35
190
0
20
0.00
0.60
0.0
7.0
—
28.49
—
0
15
70
538
1.17
0.60
5.1
5.4
38.11
45.06
ug/min
0.68
55
417
0
21
0.00
0.60
0.0
5.8
—
27.03
—
0
13
27
209
1.29
0.60
6.5
5.8
90.19
38.90
ug/min
1.13
21
158
88
512
1.15
0.59
3.9
5.6
36.72
45.07
ug/min
0.60
58
403
34
269
1.25
0.58
6.1
5.5
50.44
42.07
ug/min
0.21
25
211
91
511
1.14
0.56
4.8
5.5
53.79
42.26
ug/min
0.67
63
398
70
540
1.16
0.56
5.1
5.4
38.11
45.02
ug/min
0.67
55
418
65
333
1.17
0.55
4.7
5.6
47.96
45.44
ug/min
0.11
49
264
20
150
1.33
0.55
6.0
5.8
43.57
50.63
ug/min
0.36
14
123
41
300
1.21
0.54
4.4
5.8
40.48
45.25
ug/min
0.23
27
249
11
74
1.49
0.53
10.9
5.8
28.20
41.37
ug/min
—
5
60
6
39
1.54
0.53
4.3
7.0
38.97
34.24
ug/min
—
6
32
17
125
1.36
0.53
4.6
4.6
17.33
36.78
ug/min
1.94
12
76
38
303
1.21
0.52
5.1
5.4
33.88
37.29
ug/min
0.12
26
218
54
263
1.18
0.52
4.6
5.2
51.04
48.41
ug/min
0.10
45
201
21
271
0.77
0.52
4.1
5.6
52.87
43.12
ug/min
0.21
15
199
12
169
0.71
0.51
3.6
5.9
17.17
38.17
ug/min
—
6
118
6
40
1.50
0.51
4.0
7.3
86.13
28.91
ug/min
—
6
26
6
40
1.50
0.51
5.5
6.0
18.00
56.50
ug/min
—
6
31
13
92
1.41
0.50
6.5
6.2
63.00
49.33
ug/min
0.26
13
69
34
230
0.82
0.49
4.2
5.5
22.00
33.95
ug/min
1.46
24
159
12
83
1.43
0.49
4.4
5.2
28.29
50.18
ug/min
—
7
59
7
47
1.49
0.47
9.1
5.8
43.29
43.74
ug/min
—
7
34
23
231
0.79
0.47
3.6
5.6
57.13
47.66
ug/min
0.20
15
196
16
64
1.36
0.47
4.3
6.0
34.20
32.56
ug/min
—
10
50
20
155
1.29
0.46
5.7
6.0
57.29
44.26
ug/min
0.19
14
113
21
266
0.79
0.46
3.1
5.6
66.38
45.22
ug/min
0.48
13
221
11
58
1.45
0.46
2.0
5.5
67.55
42.10
ug/min
0.76
11
48
53
493
0.86
0.46
4.9
5.4
44.90
42.47
ug/min
0.09
40
368
16
120
1.33
0.46
5.6
5.2
32.09
38.54
ug/min
0.30
11
90
95
442
1.12
0.44
5.9
5.3
46.89
44.64
ug/min
0.14
66
346
23
192
0.80
0.44
4.7
4.9
31.69
33.38
ug/min
0.07
16
132
53
398
1.15
0.43
4.8
5.5
40.19
41.24
ug/min
0.05
37
309
6
60
0.65
0.43
8.5
5.7
44.00
53.33
ug/min
—
6
51
17
151
0.77
0.43
3.3
5.5
30.20
29.25
ug/min
—
10
95
15
129
0.76
0.42
6.9
4.5
22.63
29.15
ug/min
—
8
82
8
57
1.40
0.42
5.0
6.2
84.13
45.53
ug/min
—
8
42
26
212
1.23
0.42
6.0
5.4
27.57
42.15
ug/min
0.92
14
157
22
176
1.25
0.41
3.8
5.6
63.75
41.73
ug/min
0.46
12
126
13
96
1.35
0.41
3.0
5.7
22.32
31.93
ug/min
—
8
63
5
33
1.52
0.41
7.8
6.1
16.40
60.19
ug/min
—
5
27
0
16
0.00
0.41
0.0
9.1
—
50.20
—
0
10
66
454
1.13
0.41
5.6
5.4
37.37
44.03
ug/min
0.47
49
357
10
66
1.43
0.41
2.3
5.8
40.20
28.84
ug/min
—
5
51
30
251
0.83
0.40
7.3
5.3
24.40
43.49
ug/min
2.27
20
188
23
186
1.24
0.40
4.6
5.8
19.28
45.73
ug/min
3.91
13
139
0
18
0.00
0.40
0.0
7.0
—
35.62
—
0
13
0
18
0.00
0.40
0.0
7.0
—
35.62
—
0
13
25
122
1.23
0.39
5.3
5.6
37.84
46.58
ug/min
0.46
20
105
5
35
1.43
0.39
3.8
6.3
71.60
60.86
ug/min
—
5
29
24
117
1.24
0.39
4.5
5.5
37.54
48.03
ug/min
0.51
18
100
64
528
1.12
0.38
5.0
5.5
38.28
44.25
ug/min
0.51
50
409
11
78
1.38
0.38
2.6
5.8
18.80
27.69
ug/min
—
5
50
18
142
1.27
0.38
3.8
5.7
24.70
39.36
ug/min
—
10
112
17
114
1.28
0.38
4.7
5.5
46.75
34.20
ug/min
0.17
12
72
30
252
1.19
0.37
5.8
6.0
50.42
45.21
ug/min
0.20
24
202
9
68
1.32
0.37
7.1
5.0
35.33
49.89
ug/min
—
9
54
37
335
0.86
0.37
3.8
5.6
33.57
47.57
ug/min
1.51
30
272
18
143
1.26
0.36
3.5
6.0
20.92
40.89
ug/min
2.95
13
107
11
81
1.36
0.36
7.0
5.9
32.00
47.08
ug/min
0.74
11
57
45
221
1.15
0.35
4.9
5.3
51.72
44.85
ug/min
0.27
36
168
28
235
1.19
0.35
5.6
5.2
26.95
43.86
ug/min
1.76
22
182
6
42
1.43
0.35
3.5
6.9
61.33
59.31
ug/min
—
6
32
6
42
1.43
0.35
5.8
4.5
105.00
42.00
ug/min
—
6
30
19
88
1.26
0.35
3.9
5.9
25.77
28.31
ug/min
0.08
13
67
20
162
1.23
0.35
3.8
6.2
62.33
39.50
ug/min
0.42
15
121
20
162
1.23
0.35
5.5
5.3
28.69
43.30
ug/min
1.24
13
136
28
226
1.19
0.35
3.9
5.6
47.22
39.19
ug/min
0.28
18
176
54
445
1.13
0.35
4.5
5.6
54.54
46.33
ug/min
0.49
48
347
76
548
0.91
0.34
5.6
5.5
36.66
44.10
ug/min
0.71
54
428
14
109
1.28
0.33
3.5
5.8
22.33
40.20
ug/min
—
9
81
16
127
1.26
0.33
5.3
5.6
32.80
36.73
ug/min
—
10
82
30
256
1.17
0.33
4.6
5.6
43.68
46.79
ug/min
0.11
22
206
16
127
0.80
0.33
3.4
5.3
28.00
25.89
ug/min
—
8
74
19
231
0.82
0.32
4.7
5.5
34.38
42.16
ug/min
0.43
13
166
17
180
0.81
0.32
3.6
5.8
47.58
52.54
ug/min
0.12
12
156
6
47
1.28
0.32
5.2
5.6
12.17
44.84
ug/min
—
6
37
42
184
1.14
0.31
6.4
5.7
62.62
35.98
ug/min
1.05
30
139
19
230
0.83
0.31
4.7
5.5
34.38
42.31
ug/min
0.44
13
165
7
52
1.35
0.31
4.9
5.7
53.43
45.50
ug/min
—
7
42
7
52
1.35
0.31
9.1
5.0
43.29
58.77
ug/min
—
7
43
7
80
0.71
0.31
6.6
4.9
47.57
59.01
ug/min
—
7
69
34
212
0.87
0.30
6.1
5.0
22.36
32.42
ug/min
1.67
22
145
7
54
1.30
0.30
4.9
5.7
53.43
45.30
ug/min
—
7
43
16
129
1.24
0.30
4.1
5.3
27.73
47.29
ug/min
1.36
11
100
70
532
0.91
0.28
4.6
5.5
43.50
43.92
ug/min
0.02
42
418
62
406
0.91
0.28
6.0
5.4
38.06
44.78
ug/min
0.56
48
324
8
65
1.23
0.27
9.6
5.8
41.25
41.22
ug/min
—
8
50
14
113
1.24
0.26
3.6
6.3
22.71
41.90
ug/min
—
7
88
94
527
1.08
0.26
5.1
5.4
39.48
45.99
ug/min
0.74
71
411
10
77
1.30
0.26
5.8
6.7
59.60
51.42
ug/min
—
10
67
11
84
1.28
0.25
2.6
5.5
18.80
32.61
ug/min
—
5
53
17
142
1.20
0.24
5.2
6.2
26.53
41.44
ug/min
1.08
17
116
57
511
1.09
0.24
6.4
5.3
39.33
45.29
ug/min
0.30
43
397
12
119
0.81
0.24
2.0
5.7
64.67
57.15
ug/min
0.18
12
103
94
444
1.07
0.24
5.8
5.3
45.17
44.64
ug/min
0.03
64
346
5
38
1.32
0.23
3.2
6.0
76.00
56.31
ug/min
—
5
32
17
143
1.19
0.23
3.6
5.8
33.56
40.99
ug/min
—
10
104
5
39
1.28
0.23
6.2
7.3
26.00
45.62
ug/min
—
5
24
50
317
1.10
0.22
4.4
5.5
35.36
41.74
ug/min
0.33
32
225
11
78
0.80
0.22
3.7
5.4
26.00
24.59
ug/min
—
6
54
48
435
1.10
0.22
4.9
5.6
34.46
44.75
ug/min
0.85
37
333
26
228
1.14
0.22
3.4
5.6
18.10
40.92
ug/min
—
10
172
18
153
1.18
0.22
5.5
6.0
22.00
42.60
ug/min
2.10
12
113
37
214
0.90
0.21
7.8
5.0
45.15
32.27
ug/min
0.49
26
146
25
217
1.14
0.21
4.6
5.4
30.58
39.02
ug/min
0.31
12
153
62
492
1.08
0.21
7.5
5.2
47.30
43.25
ug/min
0.17
50
371
14
115
1.20
0.21
2.9
5.7
29.80
40.64
ug/min
—
5
79
0
14
0.00
0.20
0.0
5.9
—
36.44
—
0
9
16
136
1.18
0.20
4.1
5.9
54.14
40.45
ug/min
—
7
109
18
155
1.16
0.19
5.3
5.4
37.83
44.20
ug/min
0.29
12
114
6
51
1.18
0.19
5.3
6.2
56.50
37.31
ug/min
—
6
38
65
536
0.94
0.17
5.6
5.4
40.90
43.86
ug/min
0.13
49
410
5
46
0.71
0.17
8.4
5.4
46.80
61.37
ug/min
—
5
38
48
306
1.08
0.17
4.8
5.5
47.63
46.91
ug/min
0.03
38
245
8
70
1.14
0.16
2.0
6.7
65.38
52.23
ug/min
—
8
52
15
121
1.16
0.15
9.1
5.6
57.93
43.21
ug/min
0.47
15
92
6
76
0.79
0.15
3.7
6.7
56.00
50.00
ug/min
—
6
56
34
357
0.92
0.15
4.2
5.5
55.00
47.32
ug/min
0.28
23
285
7
73
0.79
0.14
6.6
4.9
47.57
57.56
ug/min
—
7
62
17
150
1.13
0.14
4.4
6.1
32.18
52.62
ug/min
1.35
11
121
73
528
0.95
0.13
4.8
5.6
42.24
44.41
ug/min
0.09
45
415
18
201
0.90
0.13
4.1
5.7
44.36
40.73
ug/min
0.05
11
141
10
84
1.19
0.13
8.9
5.6
51.40
45.76
ug/min
—
10
67
18
158
1.12
0.13
6.1
5.5
70.54
47.97
ug/min
0.50
13
128
40
374
1.07
0.13
5.2
5.7
45.13
45.00
ug/min
0.01
30
293
12
104
1.14
0.11
3.2
5.1
13.00
27.35
ug/min
—
5
62
19
206
0.91
0.11
4.7
5.6
34.38
42.15
ug/min
0.42
13
149
63
414
0.96
0.09
5.5
5.4
32.95
45.19
ug/min
1.20
44
325
20
184
1.09
0.09
4.7
5.4
85.80
39.91
ug/min
—
10
128
70
398
0.96
0.09
6.3
5.5
51.66
44.77
ug/min
0.39
53
312
6
54
1.11
0.09
2.8
5.6
101.67
57.83
ug/min
—
6
48
32
302
1.06
0.08
4.4
5.5
50.73
43.92
ug/min
0.34
22
235
10
113
0.88
0.08
2.3
6.2
40.20
31.70
ug/min
—
5
75
30
276
1.06
0.08
4.8
5.1
28.67
42.28
ug/min
0.75
15
202
10
88
1.14
0.08
4.3
5.2
55.80
47.60
ug/min
—
10
68
8
91
0.88
0.06
6.1
5.6
54.38
46.97
ug/min
—
8
76
22
199
1.07
0.06
4.9
5.9
68.00
53.53
ug/min
0.28
17
171
29
256
0.95
0.06
3.4
5.9
49.13
52.06
ug/min
0.11
23
216
16
148
1.08
0.06
4.8
5.3
37.36
37.61
ug/min
0.01
11
108
16
148
1.08
0.06
5.2
5.7
32.80
39.48
ug/min
—
10
103
40
368
0.96
0.06
5.9
5.5
39.85
43.87
ug/min
0.20
33
291
14
151
0.93
0.05
5.9
5.0
36.71
43.56
ug/min
—
7
109
29
255
0.96
0.05
3.4
5.9
49.13
52.06
ug/min
0.11
23
216
13
120
1.08
0.04
3.9
5.9
22.25
41.29
ug/min
—
8
87
21
171
1.06
0.04
2.9
5.7
56.75
52.28
ug/min
0.13
16
147
18
191
0.94
0.04
5.3
5.7
38.58
43.47
ug/min
0.17
12
139
15
84
0.93
0.04
4.8
5.3
36.50
31.09
ug/min
—
10
60
54
352
1.03
0.04
6.4
5.3
33.25
44.86
ug/min
0.60
34
272
37
215
0.96
0.04
6.4
5.1
48.11
32.28
ug/min
0.62
28
156
14
131
1.07
0.03
5.0
6.2
30.33
43.95
ug/min
—
9
97
49
257
0.97
0.03
3.7
5.3
51.77
47.36
ug/min
0.13
32
207
26
270
0.96
0.03
4.8
5.6
20.00
48.85
ug/min
4.80
17
226
30
235
1.04
0.03
4.2
5.7
48.04
47.89
ug/min
0.01
24
201
73
475
0.98
0.03
3.9
5.7
41.97
47.06
ug/min
0.39
58
380
26
251
1.04
0.02
5.7
5.4
28.15
40.94
ug/min
1.22
20
191
62
520
1.02
0.02
4.4
5.6
57.30
41.94
ug/min
0.70
40
403
54
392
1.02
0.02
5.9
5.5
38.95
44.10
ug/min
0.34
41
313
12
108
1.07
0.02
9.6
5.8
50.50
43.95
ug/min
0.15
12
83
42
369
1.02
0.02
7.8
5.2
37.60
41.32
ug/min
0.25
30
274
25
217
0.97
0.01
3.1
5.9
52.63
52.18
ug/min
0.01
19
188
30
270
0.98
0.01
4.2
5.2
36.75
34.17
ug/min
0.08
20
190
14
92
0.95
0.01
4.7
5.2
21.88
23.08
ug/min
—
8
56
19
196
0.97
0.00
4.9
5.5
35.93
37.60
ug/min
0.06
14
157
45
256
0.99
0.00
5.8
5.3
47.17
47.24
ug/min
0.00
30
206
20
198
1.01
0.00
4.0
5.6
29.58
38.15
ug/min
0.49
12
153
15
100
1.01
0.00
3.7
4.8
19.78
31.37
ug/min
—
9
64
37
235
0.98
0.00
4.9
5.3
28.04
35.40
ug/min
0.62
26
160
43
319
1.01
0.00
4.1
5.5
24.07
36.95
ug/min
1.36
23
231
10
94
1.05
0.00
8.7
5.9
55.10
45.00
ug/min
—
10
74
28
228
1.00
0.00
3.4
5.7
49.86
48.59
ug/min
0.04
22
196
39
294
1.00
0.00
4.5
5.4
39.03
44.17
ug/min
0.37
32
232
38
316
0.99
0.00
3.2
6.0
44.86
47.75
ug/min
0.13
29
262
18
178
1.01
0.00
4.1
5.7
44.36
40.42
ug/min
0.06
11
123
34
280
1.01
0.00
5.3
5.7
66.69
40.67
ug/min
0.79
26
217
5
58
0.86
0.00
9.8
6.4
26.80
54.81
ug/min
—
5
44
0
8
0.00
0.00
0.0
7.8
—
27.38
—
0
8
5
59
0.85
-0.00
3.6
5.9
65.40
55.96
ug/min
—
5
50
0
5
0.00
-0.00
0.0
4.6
—
22.80
—
0
5
0
5
0.00
-0.00
0.0
4.8
—
53.80
—
0
5
0
5
0.00
-0.00
0.0
6.8
—
20.40
—
0
5
0
6
0.00
-0.00
0.0
4.5
—
39.33
—
0
6
0
9
0.00
-0.00
0.0
8.2
—
46.67
—
0
9
5
51
0.98
-0.00
9.6
4.6
71.00
42.54
ug/min
—
5
39
17
170
1.00
-0.00
4.9
5.7
54.25
40.79
ug/min
0.26
12
120
6
66
0.91
-0.00
5.3
5.5
52.33
48.04
ug/min
—
6
53
0
5
0.00
-0.00
0.0
7.2
—
18.20
—
0
5
0
5
0.00
-0.00
0.0
11.2
—
34.60
—
0
5
5
57
0.88
-0.00
10.2
6.0
36.00
54.04
ug/min
—
5
44
0
5
0.00
-0.00
0.0
6.6
—
8.48
—
0
5
0
5
0.00
-0.00
0.0
6.8
—
27.00
—
0
5
0
9
0.00
-0.00
0.0
8.2
—
46.67
—
0
9
0
5
0.00
-0.00
0.0
4.8
—
53.80
—
0
5
0
5
0.00
-0.00
0.0
4.6
—
27.20
—
0
5
14
140
1.00
-0.00
3.6
5.3
48.13
42.19
ug/min
—
8
108
0
7
0.00
-0.00
0.0
5.4
—
24.71
—
0
7
0
5
0.00
-0.00
0.0
7.6
—
27.00
—
0
5
6
50
1.00
-0.00
7.3
4.8
42.83
54.67
ug/min
—
6
43