Crohn disease (strict definition, require KELA, min 2 HDR)

K11_CD_STRICT2

Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • K11_KELACROHN
  • and K11_CROHNnumber of events
  • >1
3129

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K50
  • Hospital discharge: ICD-9 555
  • Hospital discharge: ICD-8 5630
  • Cause of death: ICD-10 K50
  • Cause of death: ICD-9 555
  • Cause of death: ICD-8 5630

2 out of 7 registries used, show all original rules.

2923

4. Check minimum number of events

None

2923

5. Include endpoints

None

2923

6. Filter based on genotype QC (FinnGen only)

2684

Control definitions (FinnGen only)

Control conditions
not K11_KELACROHN

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
K50-K52
Name in latin
Morbus Crohn

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12555 6354 6153
Only index persons 12138 6175 5963
Unadjusted period prevalence (%)
Whole population 0.18 0.18 0.17
Only index persons 0.23 0.23 0.23
Median age at first event (years)
Whole population 35.44 35.86 34.99
Only index persons 35.17 35.59 34.74

-FinnGen-

Key figures

All Female Male
Number of individuals 2684 1552 1132
Unadjusted period prevalence (%) 0.54 0.55 0.52
Median age at first event (years) 39.76 38.58 41.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2787
Matched controls
27870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
122.6
307.7
939
115
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
307.7
2787
535
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.7
307.7
1329
4548
253, ,
Kela drug reimbursment
88.4
307.7
182
22
L04AB02
ATC
infliximab; parenteral
41.0
307.7
237
63
A07EC02
ATC
mesalazine; oral, rectal
63.4
307.7
1710
681
JF1BD
NOMESCO Finland
Very extensive small bowel CT
75.8
307.7
204
29
K50.1
ICD-10 Finland
Crohn disease of large intestine
325.4
307.7
1225
67
H02AB06
ATC
prednisolone; systemic
5.3
307.7
2000
9063
K50.0
ICD-10 Finland
Crohn disease of small intestine
741.7
307.7
1913
82
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
121.8
307.7
580
60
JF1AD
NOMESCO Finland
Small bowel CT
59.3
307.7
249
46
3042, ,
Kela drug reimbursment
88.4
307.7
182
22
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
12.2
307.7
483
469
A07EA06
ATC
budesonide; oral, local oral
128.1
307.7
1819
403
C10AC01
ATC
colestyramine; oral
15.3
307.7
367
273
D94
ICPC
Chronic enteritis/ulcerative colitis
43.4
307.7
264
67
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
229.4
307.7
212
10
L04AX01
ATC
azathioprine; systemic
73.2
307.7
1585
493
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
135.8
307.7
366
31
L01BB02
ATC
mercaptopurine; oral
70.0
307.7
652
121
K50
ICD-10 Finland
Crohn disease [regional enteritis]
332.6
307.7
447
16
K50.8
ICD-10 Finland
Other Crohn disease
585.7
307.7
1839
92
UJF92
NOMESCO Finland
Capsular endoscopy
53.9
307.7
809
210
ZX120
NOMESCO Finland
Intravenous
6.7
307.7
639
1190
L04AB04
ATC
adalimumab; parenteral
29.2
307.7
667
297
256, ,
Kela drug reimbursment
202.8
307.7
241
13
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
14.1
307.7
473
398
UJF32
NOMESCO Finland
Coloscopy
19.3
307.7
2078
3674
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
7.7
307.7
1660
4460
UJF30
NOMESCO Finland
Ileoscopy through colon
23.8
307.7
1588
1469
L04AX03
ATC
methotrexate; systemic
6.8
307.7
761
1451
L04AC05
ATC
ustekinumab; parenteral
79.3
307.7
298
42
K50.9
ICD-10 Finland
Crohn disease, unspecified
379.8
307.7
1522
88
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
26.1
293.9
206
85
JFB20
NOMESCO Finland
Ileocaecal resection
41.1
280.0
170
44
P01AB01
ATC
metronidazole; oral, rectal
3.8
260.7
1661
7777
A07EC01
ATC
sulfasalazine; oral, rectal
5.9
258.9
536
1087
4AA12, ,
NOMESCO Finland
48.4
252.0
147
32
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
12.7
251.6
254
219
L04AG05
ATC
vedolizumab; parenteral
65.9
251.2
138
22
L04AA33
ATC
[U] vedolizumab
105.4
234.8
121
12
4AB02, ,
NOMESCO Finland
42.1
232.3
140
35
K51.5
ICD-10 Finland
Left sided colitis
8.8
230.7
306
385
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.4
228.2
314
413
A07EA02
ATC
hydrocortisone; rectal
11.7
225.9
239
221
JFB00
NOMESCO Finland
Partial resection of small intestine
19.0
210.4
168
94
J01MA02
ATC
ciprofloxacin; systemic
3.3
202.1
1389
6522
K51.8
ICD-10 Finland
Other ulcerative colitis
12.9
200.6
198
164
H02AB07
ATC
prednisone; oral
4.3
197.2
623
1768
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
27.3
194.1
133
51
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.8
192.3
500
1219
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.1
190.7
1523
7724
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
16.8
187.9
159
100
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
20.6
183.8
141
72
B03BA03
ATC
hydroxocobalamin; parenteral
7.3
183.2
285
429
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
171.9
1536
8146
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
18.7
152.7
122
68
WX002
NOMESCO Finland
Sedation and analgesia
3.3
149.8
722
2674
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
147.9
852
3498
K60.3
ICD-10 Finland
Anal fistula
9.2
147.8
184
212
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
8.7
136.6
178
217
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
4.5
135.6
366
908
UJF02
NOMESCO Finland
Peroral enteroscopy
28.0
128.4
87
32
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.6
125.0
323
773
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
46.8
124.3
73
16
K56.7
ICD-10 Finland
Ileus, unspecified
11.5
121.0
127
115
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
10.5
118.1
132
131
WVA20
NOMESCO Finland
Medicine administration
6.5
115.9
197
323
B81
ICPC
Anaemia vit B12/folate deficiency
6.9
115.1
183
280
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
108.1
516
1868
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.0
106.7
568
2188
A02BC02
ATC
pantoprazole; systemic
2.6
106.0
2026
14189
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
10.2
103.7
118
120
JHA00
NOMESCO Finland
Anal or perianal incision
8.0
102.9
142
185
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
98.9
410
1359
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.7
95.0
326
955
A06AC01
ATC
ispaghula (psylla seeds); oral
2.5
93.6
808
3945
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
92.5
792
3850
K61.0
ICD-10 Finland
Anal abscess
6.8
91.4
146
224
M45
ICD-10 Finland
Ankylosing spondylitis
6.4
90.7
155
255
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
90.6
522
2085
K83.0
ICD-10 Finland
Cholangitis
9.9
89.3
104
109
L04AF03
ATC
upadacitinib; oral
18.0
88.9
72
41
N02AX02
ATC
tramadol; systemic, rectal
2.2
87.6
1274
7713
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
33.6
87.5
56
17
107
Kela drug reimbursment
Pernicious anaemia
9.5
83.4
100
109
3AC01, ,
NOMESCO Finland
11.4
79.0
83
75
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
43.4
78.5
47
11
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
21.1
77.0
58
28
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.1
76.7
222
574
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
105.6
75.3
82
8
L04AC18
ATC
risankizumab; parenteral
25.2
74.0
52
21
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
92.7
73.3
81
9
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.7
73.2
94
112
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
726.8
72.5
71
*
L01BA01
ATC
methotrexate; systemic
4.7
72.5
172
381
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
361.3
71.0
71
*
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
23.1
68.8
50
22
A02BC01
ATC
omeprazole; systemic
2.2
68.8
783
4218
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.8
68.4
219
608
JFB30
NOMESCO Finland
Right hemicolectomy
11.0
65.4
70
65
Z93.2
ICD-10 Finland
Ileostomy status
20.3
65.3
50
25
WW200
NOMESCO Finland
Immunization
4.8
63.9
150
329
A02BC03
ATC
lansoprazole; oral
2.1
63.7
778
4288
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.5
62.3
456
2024
298, ,
Kela drug reimbursment
13.4
61.4
58
44
JAH00
NOMESCO Finland
Laparotomy
5.4
57.7
117
226
3029
Kela drug reimbursment
Upadacitinib
12.1
57.5
58
49
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.0
57.4
126
261
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
56.5
770
4391
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
53.6
712
4012
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
5.1
52.7
114
233
D64.9
ICD-10 Finland
Anaemia, unspecified
2.9
52.0
272
1017
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
51.9
365
1582
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
6.4
51.8
86
137
R50.9
ICD-10 Finland
Fever, unspecified
2.2
51.1
524
2671
H02AB09
ATC
hydrocortisone; systemic
4.4
49.6
126
294
4AA33, ,
NOMESCO Finland
80.2
49.1
55
7
A05AA02
ATC
ursodeoxycholic acid; oral
5.0
48.7
106
218
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
90.1
48.0
53
6
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.9
47.4
234
846
WZC30
NOMESCO Finland
Teaching
2.2
47.0
493
2530
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.6
46.7
303
1262
UJD02
NOMESCO Finland
Gastroscopy
3.6
46.5
162
475
JHD20
NOMESCO Finland
Incision of fistula-in-ano
7.1
46.2
70
101
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
16.5
46.1
39
24
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.4
45.1
169
519
A02BC05
ATC
esomeprazole; systemic
1.8
44.7
1096
7445
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
44.6
195
658
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
17.0
44.5
37
22
D01
ICPC
Abdominal pain/cramps general
2.1
43.9
463
2375
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.3
43.8
114
271
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
223.4
43.0
44
*
N02BE01
ATC
paracetamol; systemic, rectal
2.3
42.2
2469
21552
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.8
42.2
226
853
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.7
42.0
242
949
K29.8
ICD-10 Finland
Duodenitis
9.2
41.3
50
55
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.6
40.5
259
1069
5550A
ICD-9 Finland
Regional enteritis, Small intestine
109.2
39.8
43
*
A07AA09
ATC
vancomycin; oral
6.5
39.7
65
102
K59.1
ICD-10 Finland
Functional diarrhoea
2.8
39.7
212
799
J01MA12
ATC
levofloxacin; systemic
2.0
39.4
467
2496
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
5.7
39.3
73
130
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
39.2
555
3156
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.3
39.2
103
247
K92.1
ICD-10 Finland
Melaena
3.3
39.0
153
483
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.6
38.9
94
211
A06AC51
ATC
ispaghula, combinations; oral
3.2
38.2
158
515
C05AA08
ATC
fluocortolone; rectal, topical
2.2
37.5
359
1767
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
37.1
1258
9198
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
70.9
37.0
42
6
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.7
37.0
87
191
5551A
ICD-9 Finland
Regional enteritis, Large intestine
192.6
36.9
38
*
1370
FHL
Colonoscopy, whole colon
12.1
36.8
37
31
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
36.7
277
1233
WX402
NOMESCO Finland
General anaesthesia
1.8
35.7
683
4257
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
35.5
777
5036
J01DB01
ATC
cefalexin; oral
1.9
35.4
2343
20381
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
8.0
35.4
48
61
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
351.6
35.0
35
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
34.7
653
4046
K61.1
ICD-10 Finland
Rectal abscess
11.4
34.5
36
32
ZX112
NOMESCO Finland
Subcutaneous
4.4
33.8
86
201
A02BA02
ATC
ranitidine; systemic
2.0
32.6
434
2404
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
32.6
1240
9237
K56.0
ICD-10 Finland
Paralytic ileus
7.7
32.3
45
59
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
6.2
32.3
55
90
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
62.5
32.1
37
6
UJH02
NOMESCO Finland
Anoscopy
3.1
32.0
136
451
ZXE00
NOMESCO Finland
One hour or less
1.6
32.0
1038
7427
UJF30, ,
SPAT
6.1
31.9
55
91
K29.7
ICD-10 Finland
Gastritis, unspecified
3.3
31.4
120
373
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
31.1
414
2292
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.8
31.0
97
264
A07DA03
ATC
loperamide; oral
3.8
30.9
97
265
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
29.6
1161
8650
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
29.1
921
6513
E0000UV, ,
ATC
1.6
29.1
1172
8775
B80
ICPC
Iron deficiency anaemia
3.4
29.1
105
315
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
9.8
28.6
33
34
JAH01
NOMESCO Finland
Laparoscopy
2.7
28.2
157
603
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.0
28.1
130
452
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
28.0
862
6044
D07AC01
ATC
betamethasone; topical
1.6
28.0
953
6845
ZXD05
NOMESCO Finland
Urgent procedure
1.6
27.8
810
5600
J05AB11
ATC
valaciclovir; oral
1.9
27.7
414
2374
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.6
27.7
93
266
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
27.6
1003
7307
B02.9
ICD-10 Finland
Zoster without complication
2.5
27.4
183
768
D99
ICPC
Disease digestive system other
5.7
27.4
51
91
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
4.3
27.3
71
169
JFA60
NOMESCO Finland
Stricturoplasty in small intestine
273.6
26.8
27
*
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
7.9
26.4
36
46
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
26.3
908
6521
K65.0
ICD-10 Finland
Acute peritonitis
6.3
26.2
44
71
D07XC01
ATC
betamethasone; topical
2.0
25.9
318
1707
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.8
25.8
79
212
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
25.7
533
3362
4AC05, ,
NOMESCO Finland
136.3
25.6
27
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.6
25.3
83
234
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.2
25.0
100
320
TJF80
NOMESCO Finland
Ostomy education
6.5
24.7
40
62
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
10.1
24.7
28
28
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
3.6
24.6
81
229
WX004
NOMESCO Finland
Patient-controlled sedation
9.4
24.4
29
31
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
24.1
181
801
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
24.0
1033
7752
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
56.5
24.0
28
5
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.4
24.0
47
88
H02AB04
ATC
methylprednisolone; systemic
1.9
23.9
358
2048
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
4.4
23.7
59
136
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
23.2
574
3783
K60.2
ICD-10 Finland
Anal fissure, unspecified
3.6
23.1
77
219
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.8
22.8
113
409
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.9
22.8
109
387
L52
ICD-10 Finland
Erythema nodosum
5.8
22.4
41
72
UJF34
NOMESCO Finland
Left colonoscopy
8.0
22.2
30
38
J02AC01
ATC
fluconazole; systemic
1.5
22.1
1026
7789
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.4
22.0
81
246
M05BA04
ATC
alendronic acid; oral
2.4
22.0
155
667
UJG02
NOMESCO Finland
Proctoscopy
3.6
21.7
71
200
D11
ICPC
Diarrhoea
1.8
21.6
401
2442
R11
ICD-10 Finland
Nausea and vomiting
2.0
21.6
261
1389
K60.1
ICD-10 Finland
Chronic anal fissure
3.2
21.6
88
285
B01AB05
ATC
enoxaparin; parenteral
1.6
21.5
691
4841
A03CA02
ATC
clidinium and psycholeptics; oral
2.7
21.3
120
464
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
20.9
21.2
31
15
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
21.1
376
2262
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
20.7
781
5659
S01BA01
ATC
dexamethasone; ophthalmic
2.9
20.4
94
327
D50.8
ICD-10 Finland
Other iron deficiency anaemias
4.1
20.4
55
135
R10.0
ICD-10 Finland
Acute abdomen
2.7
20.3
109
411
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
20.3
158
710
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
6.0
20.0
35
59
M01AH01
ATC
celecoxib; oral
1.7
19.9
385
2370
Z2221
NOMESCO Finland
Medical doctor
1.5
19.8
698
4979
WW500
NOMESCO Finland
Blood transfusion
2.7
19.6
107
407
JFF13
NOMESCO Finland
Terminal enterostomy
16.5
19.6
31
19
Z3231
NOMESCO Finland
Registered nurse
1.5
19.6
663
4684
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
19.5
201
1011
D07AD01
ATC
clobetasol; topical
1.7
19.3
418
2650
WX610
NOMESCO Finland
Patient controlled analgesia
5.5
19.3
37
68
E86
ICD-10 Finland
Volume depletion
3.7
19.1
59
160
J05AB01
ATC
aciclovir; systemic
1.6
19.0
562
3847
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
3.7
18.9
59
161
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
18.7
276
1568
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.3
18.6
150
685
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.4
18.5
130
559
Z93.3
ICD-10 Finland
Colostomy status
6.3
18.5
31
50
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.1
18.4
38
75
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.6
18.3
103
398
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.3
18.3
68
208
R4190
NOMESCO Finland
Nutritional therapy
2.3
18.3
136
599
K60.4
ICD-10 Finland
Rectal fistula
17.7
18.2
28
16
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
4.1
18.2
49
120
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
18.1
269
1532
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
18.0
1624
13792
JFF10
NOMESCO Finland
Loop enterostomy
6.5
17.9
29
45
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
67.0
17.7
20
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
17.6
177
881
J01FF01
ATC
clindamycin; systemic
1.5
17.5
661
4763
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
17.5
204
1072
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
4.2
17.4
46
111
UJK02
NOMESCO Finland
ERCP
3.3
17.4
64
195
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
17.4
2027
17978
K30
ICD-10 Finland
Functional dyspepsia
1.7
17.1
313
1895
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
31.7
17.0
22
7
J01AA02
ATC
doxycycline; systemic
1.4
17.0
1921
16892
S18
ICPC
Laceration/cut
1.4
16.8
1123
9007
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
16.7
288
1713
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.7
16.7
52
142
SPAT1153
SPAT
Removal of sutures
1.5
16.6
667
4862
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.1
16.5
167
834
K60.0
ICD-10 Finland
Acute anal fissure
3.7
16.5
52
143
SPAT1263
SPAT
Sampling
1.4
16.4
1058
8419
JEA00
NOMESCO Finland
Appendectomy
2.0
16.4
188
982
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.7
16.4
91
350
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
16.2
134
618
L73.2
ICD-10 Finland
Hidradenitis suppurativa
3.5
16.2
55
159
SPAT1255
SPAT
Intravenous administration of medicine
2.1
16.1
154
753
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
16.0
306
1872
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
3.9
15.9
46
119
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
15.8
260
1526
TQW99
NOMESCO Finland
Other minor procedure on skin
2.4
15.7
113
491
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
5.0
15.7
33
66
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
15.7
241
1384
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
15.7
141
673
A03FA02
ATC
cisapride; oral, rectal
2.1
15.7
153
754
KH1AD
NOMESCO Finland
CT of urinary organs
2.5
15.6
97
394
6404
FHL
Hemicolectomy on the right
+∞
15.6
15
*
D07AC13
ATC
mometasone; topical
1.5
15.6
712
5311
JF1CD
NOMESCO Finland
Extensive small bowel CT
85.6
15.6
17
*
QBA10
NOMESCO Finland
Incision of skin of trunk
4.2
15.6
41
99
K63.2
ICD-10 Finland
Fistula of intestine
19.3
15.5
23
12
S01FA02
ATC
scopolamine; ophthalmic
5.8
15.4
28
49
R51.80
ICD-10 Finland
Headache
1.5
15.2
462
3170
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.6
15.1
87
341
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
23.5
15.1
21
9
JFB01
NOMESCO Finland
Laparoscopic partial resection of small intestine
20.1
15.1
22
11
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
3.6
14.9
48
134
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
14.8
452
3101
B07.9
ICD-10 Finland
Verruca simplex
2.2
14.8
125
582
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.8
14.8
72
259
K85
ICD-10 Finland
Acute pancreatitis
3.7
14.7
46
126
D06
ICPC
Abdominal pain localized other
1.8
14.7
245
1443
K51
ICD-10 Finland
Ulcerative colitis
3.6
14.6
48
136
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
14.6
506
3568
JFA96
NOMESCO Finland
Other local operation on intestine
80.5
14.6
16
*
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
80.5
14.6
16
*
E000001, ,
ATC
1.5
14.4
517
3673
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.7
14.3
269
1637
D06BX01
ATC
metronidazole; topical
1.7
14.3
261
1576
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
14.3
229
1332
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
6.2
14.2
24
39
Z93
ICD-10 Finland
Artificial opening status
13.4
14.2
24
18
L73.8
ICD-10 Finland
Other specified follicular disorders
3.6
14.2
47
134
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.5
14.1
91
377
L04AB06
ATC
golimumab; parenteral
4.0
14.1
39
98
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
12.0
14.1
25
21
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.7
14.1
43
116
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.1
14.0
125
596
JFH10
NOMESCO Finland
Total colectomy and ileostomy
20.1
13.8
20
10
M50.8
ICD-10 Finland
Other cervical disc disorders
6.3
13.7
23
37
JKA20
NOMESCO Finland
Cholecystectomy
3.1
13.7
55
177
M25.5
ICD-10 Finland
Pain in joint
1.4
13.7
874
6893
J01DA01
ATC
[U] cefalexin
1.4
13.7
1545
13330
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.0
13.6
153
794
Z01.2
ICD-10 Finland
Dental examination
1.4
13.5
1319
11117
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
13.5
148
762
JFB96
NOMESCO Finland
Other partial excision of intestine
140.7
13.5
14
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
13.4
256
1566
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
13.2
194
1100
6403
FHL
Ileocal resection
40.3
13.1
16
*
A01AB09
ATC
miconazole; local oral
1.8
13.1
184
1028
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
13.1
93
403
L88
ICPC
Rheumatoid/seropositive arthritis
2.2
13.0
105
481
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
3.8
12.9
38
100
JN2BG
NOMESCO Finland
MRI examination of lower part of abdoment with high intensity magnet
4.7
12.8
29
62
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
12.8
1419
12155
L04AD01
ATC
ciclosporin; systemic
2.9
12.8
60
212
A02BA03
ATC
famotidine; systemic
2.7
12.7
67
252
B01AB10
ATC
tinzaparin; parenteral
1.7
12.7
242
1479
R03AC02
ATC
salbutamol; inhalant
1.3
12.6
1440
12379
M81.4
ICD-10 Finland
Drug-induced osteoporosis
9.3
12.5
25
27
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
12.4
499
3614
L88
ICD-10 Finland
Pyoderma gangrenosum
13.2
12.4
21
16
A07AA02
ATC
nystatin; oral
2.1
12.4
120
590
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.0
12.4
34
85
L40.8
ICD-10 Finland
Other psoriasis
4.6
12.4
29
64
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
12.3
889
7129
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
5.8
12.3
22
38
B82
ICPC
Anaemia other/unspecified
2.7
12.2
66
251
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
4.3
12.2
31
73
K02.1
ICD-10 Finland
Caries of dentine
1.3
12.2
1696
14973
WVA30, ,
SPAT
1.9
12.1
157
856
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.7
12.1
245
1521
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
26.8
12.0
16
6
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
12.0
243
1507
6455
FHL
Perianal fistula surgery
8.7
12.0
25
29
JFA70
NOMESCO Finland
Suture of small intestine
8.7
12.0
25
29
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.2
12.0
31
74
N06AX11
ATC
mirtazapine; oral
1.4
11.9
829
6599
N03AX16
ATC
[U] pregabalin
1.5
11.8
493
3592
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.0
11.8
126
642
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
5.1
11.7
24
47
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
3.5
11.7
40
117
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
30.1
11.6
15
5
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
11.6
257
1633
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.5
11.5
69
277
TPH04, ,
SPAT
3.8
11.5
34
90
K63.8
ICD-10 Finland
Other specified diseases of intestine
13.7
11.4
19
14
J01FA06
ATC
roxithromycin; oral
1.3
11.3
901
7310
JK3MN
NOMESCO Finland
Bile absorbtion isotope examination
35.2
11.3
14
*
J01DA09
ATC
[U] cefadroxil
1.4
11.2
649
5007
D05AX52
ATC
calcipotriol, combinations; topical
1.9
11.2
130
683
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.0
11.2
117
593
M54.5
ICD-10 Finland
Low back pain
1.3
11.1
953
7811
6402
FHL
Small bowel resection
20.1
11.1
16
8
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
11.1
2022
18430
K13.78
ICD-10 Finland
Other change in the oral mucosa
2.5
11.1
68
276
RD210, ,
NOMESCO Finland
2.7
11.1
60
229
N05CF02
ATC
zolpidem; oral
1.5
11.1
410
2919
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
13.9
11.0
18
13
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
4.5
10.9
26
58
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.7
10.9
59
225
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
10.8
2228
23642
K03.66
ICD-10 Finland
Tooth plaque
1.7
10.8
207
1266
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.5
10.8
64
256
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.9
10.8
50
176
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
10.6
188
1125
H20.1
ICD-10 Finland
Chronic iridocyclitis
3.5
10.6
35
100
Z94.4
ICD-10 Finland
Liver transplant status
5.3
10.6
21
40
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
2.7
10.6
54
200
A06AD11
ATC
lactulose; oral
1.6
10.5
244
1566
S10
ICPC
Boil/carbuncle
1.8
10.5
159
909
R52.9
ICD-10 Finland
Pain, unspecified
1.6
10.5
253
1639
S01BA04
ATC
prednisolone; ophthalmic
2.8
10.4
50
179
R06AE07
ATC
cetirizine; oral
1.3
10.4
1160
9841
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
10.3
102
506
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.9
10.3
135
738
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
10.3
239
1536
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
4.9
10.3
22
45
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
4.6
10.2
24
53
J01FA10
ATC
azithromycin; systemic
1.3
10.2
1584
14030
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.5
10.1
304
2070
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.6
10.1
258
1694
ZX114
NOMESCO Finland
Intramuscular
2.9
10.1
46
160
JN4AD
NOMESCO Finland
Body CT examination
1.6
10.1
218
1375
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.2
10.1
85
397
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
10.0
87
411
A04AA01
ATC
ondansetron; systemic, rectal
1.7
10.0
176
1052
D95
ICPC
Anal fissure/perianal abscess
3.2
10.0
38
119
K63.0
ICD-10 Finland
Abscess of intestine
14.6
10.0
16
11
4AA17, ,
NOMESCO Finland
40.2
10.0
12
*
L71.9
ICD-10 Finland
Rosacea, unspecified
2.3
9.9
72
316
H15.1
ICD-10 Finland
Episcleritis
2.8
9.9
48
173
S21
ICPC
Skin texture symptom/complaint
1.5
9.9
346
2432
A02BX02
ATC
sucralfate; oral
2.3
9.9
71
310
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.2
9.9
81
374
B02
ICD-10 Finland
Zoster [herpes zoster]
2.0
9.9
108
557
A03
ICPC
Fever
1.4
9.8
522
3961
M79.7
ICD-10 Finland
Fibromyalgia
2.1
9.8
93
455
SFA20
NOMESCO Finland
Two-surface restoration
1.3
9.8
1603
14255
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
4.7
9.8
22
47
K61.2
ICD-10 Finland
Anorectal abscess
9.6
9.8
19
20
M03BX02
ATC
tizanidine; oral
1.3
9.7
1590
14129
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
9.7
1926
17557
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
2.8
9.7
48
175
SFA10
NOMESCO Finland
One-surface restoration
1.3
9.7
1515
13386
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
9.6
705
5623
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.6
9.6
54
211
M79.6
ICD-10 Finland
Pain in limb
1.3
9.5
1083
9183
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
9.5
296
2034
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
9.4
197
1233
A02BC04
ATC
rabeprazole; oral
1.6
9.4
213
1360
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.4
9.4
600
4687
ZXH04
NOMESCO Finland
Procedure performed in other inpatient unit
4.2
9.4
24
57
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.1
9.4
38
124
WX290
NOMESCO Finland
Other blockage of nerve
1.3
9.3
1414
12421
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
8.7
9.3
19
22
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
0.6
9.3
235
3477
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.0
9.3
39
130
D07BC01
ATC
betamethasone and antiseptics; topical
1.5
9.3
252
1680
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.2
9.2
74
339
R01AD12
ATC
fluticasone furoate; nasal
1.3
9.2
878
7260
L82
ICD-10 Finland
Seborrhoeic keratosis
1.4
9.2
367
2645
L57.0
ICD-10 Finland
Actinic keratosis
1.7
9.2
150
879
N07BA03
ATC
varenicline; oral
1.8
9.2
135
767
A07EC03
ATC
olsalazine; oral
13.7
9.2
15
11
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.8
9.2
126
701
UKC02
NOMESCO Finland
Cystoscopy
1.5
9.2
258
1733
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
9.1
189
1180
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
5.0
9.1
19
38
JHD10
NOMESCO Finland
Myotomy of anal sphincter
5.0
9.1
19
38
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
9.1
286
1968
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
11.5
9.1
16
14
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
9.0
452
3392
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
15.6
9.0
14
9
D82
ICPC
Teeth/gum disease
1.3
9.0
1056
8966
SPAT1325
SPAT
Vaccination
1.3
8.9
666
5318
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
8.9
133
760
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
8.8
235
1559
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
8.8
486
3705
ZY010
NOMESCO Finland
Hospital outpatient
1.7
8.8
161
973
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
1.9
8.8
117
644
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
8.8
322
2283
K13.00
ICD-10 Finland
Cheilitis NOS
4.0
8.8
24
60
UJK12
NOMESCO Finland
Peroral cholangioscopy
9.5
8.8
17
18
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.8
8.8
42
151
R06.0
ICD-10 Finland
Dyspnoea
1.4
8.7
549
4272
R2110
NOMESCO Finland
Giving the first information
1.7
8.7
156
937
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.0
8.7
98
511
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.1
8.7
82
401
M79.1
ICD-10 Finland
Myalgia
1.4
8.6
394
2909
JN2AD
NOMESCO Finland
CT examination of lower part of abdomen
7.6
8.6
19
25
K63.9
ICD-10 Finland
Disease of intestine, unspecified
4.4
8.6
21
48
K85.8
ICD-10 Finland
Other acute pancreatitis
4.0
8.6
24
61
D70.82
ICD-10 Finland
Drug-induced neutropenia
2.9
8.6
39
136
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
8.6
128
731
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
4.1
8.5
23
57
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
4.1
8.5
23
57
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
6.4
8.5
21
33
K85.3
ICD-10 Finland
Drug-induced acute pancreatitis
20.1
8.5
12
6
S29
ICPC
Skin symptom/complaint other
1.4
8.5
462
3516
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.1
8.4
82
406
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
8.4
1437
12738
T91
ICPC
Vitamin/nutritional deficiency
3.9
8.4
24
62
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
7.9
8.4
18
23
J01CA04
ATC
amoxicillin; systemic
1.3
8.3
2246
21070
E000002, ,
ATC
1.5
8.3
274
1902
56510
ICD-8 Finland
Anal fissure and fistula, Anal fistula
10.8
8.3
15
14
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.3
8.3
570
4494
Z98.8
ICD-10 Finland
Other specified postsurgical states
2.8
8.3
39
139
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
8.2
552
4336
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
8.2
131
763
N06AX21
ATC
duloxetine; oral
1.5
8.2
287
2018
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
4.4
8.1
20
46
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
8.1
84
426
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
3.2
8.1
31
98
D07AB08
ATC
desonide; topical
1.5
8.0
254
1748
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.7
8.0
148
897
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.1
8.0
71
339
JHC60
NOMESCO Finland
Transanal submucous or intersphincteric injection
8.9
8.0
16
18
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
8.9
8.0
16
18
D28
ICPC
Limited function/disability (D)
10.0
8.0
15
15
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
10.0
8.0
15
15
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
10.0
8.0
15
15
JFB43
NOMESCO Finland
Left hemicolectomy
6.3
8.0
20
32
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
8.0
263
3700
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.4
8.0
51
212
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.7
8.0
129
755
A02BA04
ATC
nizatidine; systemic
1.8
7.9
120
688
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
7.9
298
2122
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.9
7.9
89
464
PD1AD
NOMESCO Finland
CT of abdominal aorta and branches
4.3
7.9
20
47
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.9
930
7870
L04AA01
ATC
[U] ciclosporin
3.1
7.9
32
105
N05BA04
ATC
oxazepam; oral
1.3
7.8
586
4672
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.8
7.8
121
699
SCA02
NOMESCO Finland
Preventive oral health care
1.4
7.8
301
2156
E87.6
ICD-10 Finland
Hypokalaemia
2.1
7.7
72
351
M01AX17
ATC
nimesulide; oral
1.4
7.7
417
3164
JFG26
NOMESCO Finland
Closure of terminal enterostomy with anastomosis to colon
45.1
7.7
9
*
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
7.7
1482
13262
M01AH02
ATC
rofecoxib; oral
1.5
7.7
208
1385
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
7.7
220
1483
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.7
1206
10548
M04AA01
ATC
allopurinol; systemic
1.6
7.7
187
1217
SPAT1312
SPAT
General health counselling
1.3
7.6
769
6378
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
7.6
576
4599
K90.4
ICD-10 Finland
Malabsorption due to intolerance, not elsewhere classified
18.4
7.6
11
6
R07.0
ICD-10 Finland
Pain in throat
1.5
7.6
212
1422
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.7
7.6
146
896
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
2.5
7.6
47
193
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
6.7
7.6
18
27
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
3.6
7.6
24
67
JFC20
NOMESCO Finland
Other enterocolostomy
25.1
7.6
10
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.9
7.6
89
472
OAB93, ,
SPAT
1.5
7.6
215
1448
R01AD58
ATC
fluticasone, combinations; nasal
1.3
7.6
697
5714
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.1
7.5
20
49
ULA02
NOMESCO Finland
Kolposcopy
1.5
7.5
232
1589
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
1.7
7.5
141
860
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
2.7
7.5
39
147
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.7
7.4
119
695
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.5
7.4
45
183
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
7.4
254
1779
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
7.4
523
4135
K80.8
ICD-10 Finland
Other cholelithiasis
2.6
7.3
42
166
K76.9
ICD-10 Finland
Liver disease, unspecified
2.8
7.3
35
126
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
1.6
7.3
190
1255
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.2
7.3
60
279
JHD96
NOMESCO Finland
Other incision of anal sphincter
9.4
7.3
14
15
6451
FHL
Dilatation
4.2
7.3
19
46
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.3
617
5001
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.3
7.2
54
241
L20.0
ICD-10 Finland
Besnier prurigo
1.5
7.2
229
1577
A07EA01
ATC
prednisolone; oral, rectal
6.2
7.2
18
29
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
6.2
7.2
18
29
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
2.8
7.2
35
127
UDC00
NOMESCO Finland
Ear microscopy
1.6
7.2
162
1034
K29.4
ICD-10 Finland
Chronic atrophic gastritis
2.9
7.2
33
116
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
4.3
7.2
18
42
K92.0
ICD-10 Finland
Haematemesis
2.4
7.2
47
198
JJC00
NOMESCO Finland
Allogenic transplantation of liver
7.3
7.2
16
22
A41.9
ICD-10 Finland
Sepsis, unspecified
2.1
7.2
66
321
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
30.1
7.1
9
*
Q43.0
ICD-10 Finland
Meckel diverticulum
20.1
7.1
10
5
1380
FHL
Colonoscopy, left side
20.1
7.1
10
5
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.8
7.1
94
518
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.2
7.1
54
243
K29.6
ICD-10 Finland
Other gastritis
3.0
7.0
29
96
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
7.0
224
1545
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
7.0
384
2920
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
3.9
7.0
20
52
JAD10
NOMESCO Finland
Repair of incisional hernia
3.9
7.0
20
52
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
7.0
1064
9244
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
2.4
7.0
47
201
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
2.2
7.0
53
239
M02AA10
ATC
ketoprofen; topical
1.4
7.0
301
2200
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.3
7.0
50
220
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.5
6.9
221
1524
J01CF05
ATC
flucloxacillin; systemic
1.6
6.9
176
1156
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
1.9
6.9
89
487
SPAT1254
SPAT
Administration of medicine
1.4
6.9
298
2177
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.3
6.9
51
227
A02BB01
ATC
misoprostol; oral
5.5
6.9
19
35
XW000
NOMESCO Finland
Bone marrow biopsy
2.0
6.9
75
388
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
4.0
6.9
19
48
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
2.9
6.8
30
103
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
2.7
6.8
35
131
SFA30
NOMESCO Finland
Three-surface restoration
1.2
6.8
1010
8740
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.6
6.8
137
851
EB1VA, ,
NOMESCO Finland
1.3
6.8
447
3492
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.0
6.8
69
348
F45.0
ICD-10 Finland
Somatization disorder
4.1
6.8
18
44
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
9.3
6.8
13
14
SPAT1260
SPAT
Consultation of another employee
1.4
6.8
359
2715
N06AX16
ATC
venlafaxine; oral
1.4
6.8
366
2777
4AB04, ,
NOMESCO Finland
40.1
6.8
8
*
K11.2
ICD-10 Finland
Sialoadenitis
1.9
6.7
78
412
JN2CM
NOMESCO Finland
Lower part of abdomen extensive MRI examination with Tesla magnet
4.3
6.7
17
40
TEA00
NOMESCO Finland
Biopsy of lip
3.2
6.7
25
78
H57.1
ICD-10 Finland
Ocular pain
1.7
6.7
106
618
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.5
6.7
40
162
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.2
6.7
908
7780
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
6.6
548
4421
LEB00
NOMESCO Finland
Biopsy of vagina
2.6
6.6
37
145
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
7.8
6.6
14
18
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.6
623
5111
S97
ICPC
Chronic ulcer skin
1.8
6.6
103
598
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.6
358
2719
WVA20, ,
SPAT
1.9
6.6
83
452
A04
ICPC
Weakness/tiredness general
1.4
6.6
372
2843
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
1.5
6.5
224
1568
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.5
861
7348
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
2.9
6.5
30
106
N02BF02
ATC
pregabalin; oral
1.6
6.5
152
981
ZX100
NOMESCO Finland
Oral
2.8
6.5
31
112
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
3.7
6.5
20
55
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
5.3
6.5
18
34
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.7
6.4
32
118
A55
ICPC
General and Unspecified, Local injection/infiltration
2.5
6.4
37
147
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
1.8
6.4
93
528
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
6.4
185
1250
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
70.0
6.4
7
*
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.3
6.4
636
5247
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
1.9
6.4
76
405
N32.1
ICD-10 Finland
Vesicointestinal fistula
7.4
6.4
14
19
N03AX12
ATC
[U] gabapentin; oral
1.4
6.4
320
2397
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
6.4
680
5659
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.5
6.4
170
1130
127
Kela drug reimbursment
Transplant complication
2.4
6.4
41
172
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.3
6.4
45
197
E000007, ,
ATC
1.6
6.3
126
781
R06AX27
ATC
desloratadine; oral
1.3
6.3
779
6595
A07AA11
ATC
rifaximin; oral
6.0
6.3
16
27
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
5.5
6.3
17
31
R60.0
ICD-10 Finland
Localized oedema
1.5
6.3
223
1572
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.5
6.3
21
61
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
9.3
6.3
12
13
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
6.3
250
1802
392
Kela drug reimbursment
Ferric maltol
+∞
6.3
6
*
JFB34
NOMESCO Finland
Other laparoscopic resection comprising small intestine and colon
+∞
6.3
6
*
R01AD08
ATC
fluticasone; nasal
1.3
6.2
696
5823
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.4
6.2
228
1617
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.5
6.2
218
1534
K83.1
ICD-10 Finland
Obstruction of bile duct
2.9
6.2
28
98
ECA20
NOMESCO Finland
Biopsy of gingiva
3.1
6.2
25
82
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
2.7
6.2
31
115
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
1.8
6.2
85
476
K56.2
ICD-10 Finland
Volvulus
4.0
6.2
17
43
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
6.1
142
914
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
5.7
6.1
16
28
F01
ICPC
Eye pain
1.9
6.1
78
426
WW200, ,
SPAT
1.3
6.1
634
5255
S85
ICPC
Pilonidal cyst/fistula
7.7
6.1
13
17
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.1
696
5837
N05CF01
ATC
zopiclone; oral
1.3
6.1
614
5075
M70.6
ICD-10 Finland
Trochanteric bursitis
1.4
6.1
236
1693
N20.1
ICD-10 Finland
Calculus of ureter
1.9
6.1
75
406
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
8.6
6.0
12
14
WX419
NOMESCO Finland
Other general anesthesy
3.2
6.0
23
73
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.7
6.0
108
653

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
829
2096
5.21
315.98
8.4
4.8
0.62
0.95
%
3.05
261
594
2366
11451
8.06
307.65
21.1
6.7
2.58
2.82
%
8.53
2336
10817
2612
3614
100.18
307.65
10.1
2.4
197.46
110.82
ug/g
30.15
2562
2917
2587
9526
24.91
307.65
12.6
5.0
37.11
36.67
g/l
5.16
2562
8995
327
64
57.75
307.65
2.3
1.6
103.41
122.89
au/ml
0.12
43
11
404
96
49.05
307.65
3.3
3.0
151.82
86.44
au/ml
0.90
53
24
2601
12523
17.14
307.65
21.3
6.5
0.56
0.56
e9/l
0.01
2491
10915
206
18
123.50
307.65
2.9
2.1
2.98
3.58
mg/l
0.60
200
18
2370
11472
8.12
307.65
21.2
6.8
8.74
8.61
%
1.74
2340
10850
2352
11440
7.77
307.65
21.3
6.8
0.75
0.69
%
8.73
2322
10800
458
90
60.70
307.65
3.2
2.1
9.61
8.89
mg/l
0.65
407
73
1770
5830
6.58
307.65
5.1
2.2
2.56
2.66
mg/l
1.46
1693
5075
2602
12538
17.20
307.65
21.3
6.6
0.04
0.04
e9/l
0.02
2488
10918
2629
13872
16.79
307.65
22.5
9.7
3.94
4.02
e9/l
1.43
2527
12140
2379
11876
7.85
307.65
21.1
6.6
28.35
29.12
%
3.79
2354
11348
2612
12936
17.23
307.65
21.5
6.8
0.17
0.19
e9/l
9.58
2510
11454
461
116
47.42
307.65
4.6
3.3
8.96
9.41
mg/l
0.25
399
96
2376
11670
8.03
307.65
20.5
6.5
58.25
56.37
%
18.12
2348
11227
1925
2550
22.17
307.65
2.2
1.4
—
—
—
0
0
821
2001
5.40
307.65
7.9
4.6
0.36
0.65
%
4.71
260
561
2504
10742
14.11
307.65
5.4
2.5
73.27
74.21
nmol/l
1.08
2470
9987
2608
12875
16.97
307.65
21.4
6.5
1.84
1.97
e9/l
6.38
2515
11494
802
2020
5.17
306.21
8.6
4.9
0.06
0.12
%
1.75
235
516
2727
17527
26.82
301.25
25.9
7.8
73.88
76.69
u/l
4.92
2707
16727
798
2052
5.05
296.31
9.1
5.1
0.02
0.27
%
0.88
219
484
965
3061
4.29
270.76
3.8
3.2
4.02
4.76
e9/l
2.43
860
2748
963
3086
4.24
265.81
3.0
2.6
21.61
24.08
%
6.54
940
2887
1106
3958
3.97
260.31
1.5
1.7
—
—
—
0
0
991
3384
3.99
247.78
3.0
2.5
2.44
2.39
g/l
2.06
961
3149
1032
3671
3.88
242.33
3.1
2.5
13.21
14.25
umol/l
4.13
1014
3432
1802
9307
3.65
234.04
2.8
2.0
89.37
97.13
pmol/l
12.73
1325
5132
916
3141
3.85
224.68
1.3
1.2
—
—
—
0
0
314
449
7.75
212.08
5.2
3.5
3.87
4.01
e9/l
0.58
314
449
1352
6117
3.35
211.93
14.7
4.5
—
—
—
0
0
2022
11712
3.65
208.65
8.3
6.4
10.29
11.11
umol/l
3.55
1966
11197
1298
5793
3.32
207.04
1.7
1.7
—
—
—
0
0
1938
10980
3.51
206.30
24.7
10.5
0.00
0.00
e9/l
0.64
1795
8991
2553
17443
6.52
205.54
10.0
4.1
11.76
9.85
mm/h
11.75
2496
16487
1469
7232
3.18
195.11
5.1
2.6
57.51
59.39
u/l
0.61
1405
6738
2090
12677
3.59
193.15
5.4
3.2
98.13
103.78
ug/l
0.61
2044
12043
333
574
6.45
188.21
5.1
3.3
58.66
57.21
%
1.24
333
574
363
691
5.89
185.17
1.2
1.3
273.62
242.03
u/ml
1.07
222
417
629
2053
3.67
160.40
4.1
2.4
0.24
0.22
g/l
4.04
611
1931
352
749
5.23
157.99
1.6
1.3
82.56
90.95
titre
0.19
39
84
892
3744
3.03
149.05
1.6
1.4
586.77
482.58
titre
0.88
251
744
87
21
42.73
145.07
1.1
1.3
40.59
17.88
u/ml
—
27
8
87
21
42.73
145.07
1.1
1.3
31.40
23.00
u/ml
—
24
5
763
2977
3.15
144.34
2.1
1.7
1083.24
1178.51
nmol/l
2.10
577
2312
1578
9207
2.65
135.47
2.6
2.0
—
—
—
0
0
582
2009
3.40
134.07
2.3
2.9
11.05
10.55
g/l
2.40
543
1863
258
480
5.82
133.75
1.1
1.2
—
—
—
0
0
433
1236
3.96
132.74
1.3
1.3
—
—
—
0
0
476
1452
3.75
132.57
1.4
1.2
—
—
—
0
0
1493
8582
2.59
130.63
5.1
3.3
32.06
31.03
u/l
0.21
1406
8152
495
1569
3.62
130.01
1.8
1.9
1.19
1.29
g/l
1.01
471
1470
1304
7204
2.52
121.56
2.0
2.1
—
—
—
0
0
1692
10634
2.50
117.68
8.1
7.1
1.21
1.21
mmol/l
0.50
1495
9268
1561
9477
2.47
116.88
7.2
6.6
1.21
1.21
mmol/l
1.05
1479
8850
70
17
42.21
116.35
1.1
1.2
—
—
—
0
0
899
4257
2.64
114.61
2.7
1.6
408.00
28381016.85
pmol/l
3.52
828
3668
368
1043
3.91
113.17
1.6
1.8
—
—
—
0
0
1496
9236
2.34
103.24
10.4
11.1
1.11
1.16
inr
6.38
1275
7671
1037
5508
2.41
100.92
5.1
4.3
—
—
—
0
0
1071
5770
2.39
100.92
2.0
1.6
20.34
19.95
nmol/l
0.26
1005
5055
163
257
6.67
99.45
1.8
1.4
—
—
titre
—
0
0
1056
5772
2.34
95.00
1.7
1.5
2.46
2.28
g/l
3.00
793
3755
2753
24057
12.83
78.98
36.9
13.3
14.72
22.09
mg/l
53.91
2631
19408
1074
6340
2.13
75.97
4.8
4.1
7.39
7.40
ph
1.03
800
4473
125
208
6.24
72.18
1.6
1.2
126.29
197.63
titre
0.56
35
38
125
208
6.24
72.18
1.6
1.3
128.00
196.25
titre
—
5
8
122
201
6.30
71.14
2.9
3.7
58.05
54.39
%
1.01
103
186
123
208
6.14
69.88
1.2
1.2
60.03
59.95
u/l
0.00
106
189
1146
7175
2.01
66.94
12.2
6.2
—
—
—
0
0
558
2641
2.39
66.56
1.4
1.5
—
—
—
0
0
151
322
4.90
66.54
2.7
4.0
1.04
1.44
%
0.87
134
302
488
2211
2.46
63.92
3.7
3.2
1.77
1.78
%
0.06
451
2011
285
980
3.13
63.57
1.8
1.6
4.61
10.94
iu/ml
1.06
12
34
1751
12830
1.98
63.38
4.5
3.5
0.00
0.13
estimate
0.55
499
2511
1090
6810
1.99
63.10
4.7
3.6
0.00
0.00
estimate
1.94
499
2503
1743
12767
1.98
62.96
4.4
3.5
0.00
5.41
estimate
2.54
509
2660
1730
12646
1.97
62.79
4.4
3.5
0.00
0.00
estimate
0.80
512
2642
561
2756
2.30
60.88
4.2
3.0
6.60
7.24
umol/l
0.43
494
2414
385
1640
2.56
57.10
2.6
3.1
71.67
72.75
e9/l
0.21
301
1172
1048
6634
1.93
56.94
1.4
1.4
0.86
1.60
u/ml
2.96
280
1895
252
862
3.11
56.54
1.6
1.3
—
—
—
0
0
208
636
3.45
56.05
1.7
1.3
5.87
6.04
iu/ml
—
9
12
172
465
3.88
55.65
2.0
1.7
0.62
0.77
g/l
0.95
138
367
950
5877
1.94
54.84
6.5
4.2
94.84
92.81
%
1.88
929
5757
102
183
5.75
54.47
1.1
1.1
1520.54
1568.65
miu/ml
0.14
102
183
429
1998
2.36
52.08
4.4
3.5
—
—
—
0
0
496
2505
2.19
49.40
2.1
2.2
337.26
378.27
nmol/l
5.30
468
2338
467
2329
2.21
47.88
3.5
2.6
41.43
60.58
u/l
0.43
420
1983
233
837
2.95
47.79
1.2
1.3
—
—
—
0
0
142
374
3.95
47.61
1.1
1.1
1.49
1.47
g/l
0.28
136
343
1730
13342
1.78
45.53
5.8
5.1
6.38
6.52
mmol/l
2.20
1664
12499
788
4842
1.87
44.70
3.0
2.6
5.76
6.53
e6/l
0.88
730
4395
2753
25422
7.80
43.33
33.1
10.7
26.74
27.37
u/l
1.39
2745
24857
1344
9756
1.73
42.74
4.4
3.3
0.00
0.03
estimate
1.35
459
2206
1401
10303
1.72
42.36
3.7
3.1
6.19
6.20
ph
0.23
865
5960
574
3249
1.97
41.32
2.4
2.0
—
—
—
0
0
940
6214
1.77
41.28
3.7
3.1
0.48
0.37
e6/l
0.49
749
4430
1884
15104
1.76
41.13
5.2
4.1
999.80
1345.02
e6/l
—
10
184
1127
7859
1.73
40.88
3.3
3.2
20.35
48.76
ng/l
2.13
651
4689
94
205
4.71
40.26
2.9
4.5
—
—
—
0
0
222
861
2.72
39.30
1.6
2.0
1.46
1.44
g/l
0.11
196
765
2621
23661
2.81
38.67
23.0
14.6
139.40
139.66
mmol/l
8.13
2587
23202
1040
7182
1.71
38.46
3.8
3.2
41.36
70.65
e6/l
0.70
852
5358
273
1192
2.43
37.77
1.1
1.1
—
—
—
0
0
2621
23722
2.76
37.31
23.3
14.7
3.89
3.94
mmol/l
20.20
2583
23211
176
630
2.91
36.19
1.3
1.5
—
—
—
0
0
1453
11070
1.65
36.19
3.4
2.7
—
—
estimate
—
0
0
897
6030
1.72
36.08
3.6
3.0
—
0.00
estimate
—
0
13
181
666
2.84
35.37
1.5
1.4
299.02
292.50
ug/g
0.14
92
373
1062
7535
1.66
34.48
3.3
2.3
—
—
—
0
0
501
2864
1.91
34.41
7.2
6.5
1.04
1.05
mmol/l
0.25
476
2678
362
1852
2.10
34.03
4.3
4.0
7.36
7.35
ph
0.77
303
1376
245
1075
2.40
33.43
1.8
2.0
4.52
7.78
iu/ml
1.98
63
262
77
168
4.69
32.97
1.7
1.7
—
—
—
0
0
182
697
2.72
32.94
1.3
1.2
—
—
—
0
0
156
552
2.93
32.73
3.2
3.0
2.52
1.92
index
0.34
79
314
171
636
2.80
32.73
1.3
1.5
31.10
15.70
u/ml
—
5
9
839
5673
1.69
32.31
3.1
2.3
—
—
—
0
0
1160
8556
1.61
31.38
4.4
3.8
48.80
78.31
e6/l
1.47
897
5768
116
355
3.37
31.10
4.1
3.2
535.17
50.52
u/ml
0.46
116
349
1019
7308
1.62
30.79
3.8
2.9
0.01
0.05
estimate
1.07
455
2150
652
4162
1.74
30.78
3.2
2.8
532.13
539.85
mosm/kgh2o
0.35
587
3653
215
932
2.42
30.08
1.4
1.2
—
—
—
0
0
157
596
2.73
28.89
1.3
1.5
150.19
150.70
au/ml
0.01
37
167
196
831
2.46
28.77
1.8
1.9
1.19
1.20
g/l
0.21
190
785
191
804
2.48
28.47
1.8
1.9
0.23
0.23
g/l
0.06
185
759
580
3676
1.73
27.74
5.0
3.9
0.80
0.82
mmol/l
2.47
550
3509
1020
7458
1.58
27.66
3.3
3.3
2.33
2.35
mmol/l
5.40
934
6896
472
2835
1.80
27.14
1.9
1.7
—
—
—
0
0
223
1050
2.22
25.68
1.3
1.3
0.32
1.00
u/ml
1.23
20
79
341
1879
1.93
25.67
8.5
8.6
8.15
8.45
mmol/l
0.40
333
1825
54
109
5.03
25.37
1.6
1.6
3778.46
2522.35
titre
0.65
26
17
78
212
3.76
25.04
1.1
1.1
—
—
—
0
0
658
4417
1.64
24.99
1.3
1.3
7.90
10.02
u/ml
0.44
280
1819
365
2125
1.83
23.02
4.7
4.3
7.37
7.38
ph
0.17
217
1218
354
2051
1.83
22.66
4.6
4.3
1.19
1.81
mmol/l
2.47
319
1779
163
710
2.38
22.51
4.8
3.8
41.13
2175.89
u/ml
0.89
137
611
475
3009
1.70
22.28
1.6
1.5
—
—
—
0
0
169
752
2.33
22.23
2.0
2.0
1.85
1.69
ug/l
0.08
155
675
458
2972
1.65
19.37
1.4
1.2
—
—
—
0
0
349
2105
1.75
19.37
2.1
2.0
0.06
0.02
estimate
0.45
63
487
2049
18086
1.50
19.14
5.2
3.3
43.60
42.55
u/l
0.28
1972
17340
676
4819
1.53
19.10
1.4
1.3
17.54
25.80
iu/ml
2.61
192
1377
39
78
5.06
18.56
3.7
3.1
0.58
0.62
mmol/l
2.35
39
78
242
1336
1.89
17.92
5.1
4.5
23.72
24.23
mmol/l
1.75
242
1326
557
3854
1.56
17.87
3.3
2.8
0.97
1.10
e6/l
0.30
326
1943
208
1115
1.94
16.83
2.1
2.1
0.02
0.67
estimate
0.49
51
381
301
1816
1.74
16.60
4.0
4.4
12.05
20.04
ug/l
0.50
230
1435
805
6113
1.45
16.15
3.0
2.7
—
—
—
0
0
91
356
2.61
15.85
4.3
3.9
47.12
956.42
u/ml
0.73
84
333
2756
26665
4.02
15.50
49.2
20.2
275.41
256.05
e9/l
44.51
2749
26239
2756
26682
3.96
15.13
49.0
20.2
4.48
4.59
e12/l
25.03
2748
26203
76
278
2.78
15.10
1.2
1.4
6.95
6.69
g/l
0.19
48
200
750
5683
1.44
15.03
4.5
3.5
1.02
1.56
kg/l
0.80
529
3698
2756
26688
3.94
15.00
49.1
20.3
6.83
6.69
e9/l
2.46
2748
26198
158
802
2.03
14.94
3.6
5.2
1.46
1.36
mg/l
0.73
151
747
114
513
2.27
14.66
1.1
1.1
—
—
—
0
0
75
278
2.74
14.55
1.2
1.4
3.85
3.00
g/l
2.59
47
199
75
278
2.74
14.55
1.2
1.4
0.45
0.38
g/l
0.63
47
197
109
494
2.26
13.80
1.1
1.1
—
—
—
0
0
307
1955
1.64
13.75
7.4
8.7
1.24
1.33
mmol/l
1.20
295
1914
271
1671
1.69
13.74
2.3
2.4
0.28
0.34
e6/l
0.33
260
1585
500
3573
1.49
13.41
3.3
2.9
3.93
2.70
e6/l
0.79
270
1662
72
274
2.67
13.30
1.2
1.4
—
—
—
0
0
249
1514
1.71
13.29
4.5
4.3
87.70
81.20
ng/l
0.50
223
1361
285
1816
1.63
12.71
1.4
1.4
—
—
—
0
0
229
1388
1.71
12.36
3.8
3.7
4.98
5.14
kpa
3.02
223
1342
714
5538
1.39
12.08
1.8
1.9
1.01
1.01
mg/l
0.01
499
4125
818
6487
1.37
12.07
2.1
2.2
131.45
227.96
u/l
3.66
796
6211
337
2263
1.56
12.03
1.2
1.2
—
—
—
0
0
203
1202
1.74
11.92
1.7
2.3
—
—
—
0
0
222
1350
1.70
11.84
3.8
3.7
7.42
7.41
ph
0.61
185
1138
71
285
2.53
11.82
1.3
1.3
—
—
—
0
0
289
1892
1.59
11.51
10.1
10.0
—
—
—
0
0
245
1544
1.64
11.40
2.0
2.7
65.87
67.12
g/l
1.79
229
1447
181
1058
1.76
11.12
3.1
3.3
0.67
0.61
%
0.76
181
1051
167
957
1.79
10.98
3.9
3.8
—
—
—
0
0
253
1640
1.60
10.49
3.8
3.7
1.23
1.23
mmol/l
0.18
222
1421
223
1405
1.64
10.39
1.7
1.8
0.28
0.31
mg/l
0.31
102
670
2080
19136
1.34
10.06
4.4
4.4
14.74
14.55
pmol/l
3.16
1944
17891
136
752
1.85
10.06
1.1
1.1
10.73
4.09
eliau/ml
0.36
16
114
141
791
1.82
9.96
3.8
3.9
24.62
24.69
mmol/l
0.10
135
744
737
5894
1.34
9.95
2.7
2.6
328.02
334.51
umol/l
1.04
680
5336
61
250
2.47
9.78
1.8
2.9
916.14
1311.49
e6/l
3.43
56
219
178
1076
1.70
9.72
3.1
3.4
1.33
1.35
%
0.08
178
1068
51
198
2.61
9.16
2.0
3.2
130.24
220.61
e6/l
5.13
46
169
514
3977
1.36
8.47
2.8
2.8
2.43
2.43
mmol/l
0.06
454
3585
94
489
1.95
8.42
3.7
3.3
33.18
34.25
umol/l
0.21
87
454
48
191
2.54
8.23
1.8
3.1
398.74
566.17
e6/l
1.35
42
156
36
123
2.95
8.23
2.4
3.3
0.86
0.86
index
0.00
36
123
127
745
1.74
7.78
1.4
1.3
5.25
9.03
u/ml
0.53
23
107
46
185
2.51
7.74
1.4
1.3
175877.57
97082.29
e6/l
0.21
30
124
126
741
1.73
7.66
1.3
1.3
2.19
3.07
u/ml
0.56
11
62
98
535
1.86
7.62
2.9
2.4
9.98
5.58
umol/l
1.89
73
394
276
1954
1.46
7.59
1.4
1.3
144.62
266.25
u/ml
1.49
257
1829
314
2281
1.42
7.51
9.5
8.9
4.92
5.11
kpa
3.56
302
2200
98
538
1.85
7.50
1.9
1.6
7844.43
13459.91
e6/l
1.18
82
377
19
32
5.97
7.37
1.9
1.9
—
—
—
0
0
313
2281
1.42
7.36
9.5
8.9
12.66
12.86
kpa
0.32
301
2204
131
788
1.70
7.35
1.3
1.2
31.19
32.19
u/ml
—
7
38
2349
22285
1.34
7.30
5.3
5.2
1.73
1.82
mu/l
3.31
2223
21093
630
5122
1.30
7.23
2.6
3.1
1021.64
985.47
ng/l
0.08
525
4268
854
7216
1.26
7.19
3.0
2.7
0.00
0.02
—
7
102
312
2285
1.41
7.13
9.6
9.0
7.42
7.41
ph
1.74
165
1224
422
3253
1.35
7.05
2.3
2.3
29.64
29.47
s
0.25
415
3158
308
2266
1.40
6.85
9.6
8.9
0.14
0.87
mmol/l
2.34
252
1862
32
115
2.80
6.74
1.1
1.1
193.39
214.07
iu/ml
0.18
32
115
42
176
2.41
6.53
2.8
3.1
14.25
13.56
index
0.16
36
123
86
476
1.83
6.46
2.8
3.6
—
—
—
0
0
498
3984
1.30
6.39
3.7
3.5
361.35
484.51
ng/l
0.19
297
2685
16
27
5.95
6.29
1.3
1.3
—
—
—
0
0
265
1934
1.41
6.18
10.7
9.7
121.29
123.77
g/l
1.05
259
1891
953
10873
0.81
6.16
2.6
2.8
—
—
—
0
0
239
1718
1.43
6.07
2.6
2.4
11376.11
6259.90
u/l
0.70
76
675
17
33
5.18
6.00
5.6
8.2
32.82
44.45
ug/min
0.38
11
26
119
739
1.64
5.97
1.8
2.3
203.67
345.84
ug/l
0.80
104
693
41
178
2.32
5.92
1.0
1.3
—
—
—
0
0
48
223
2.17
5.91
1.3
1.6
48.65
56.52
%
0.65
31
146
210
1490
1.44
5.74
2.3
2.2
6.06
7.44
ug/l
0.43
180
1352
274
2043
1.38
5.64
10.4
9.4
96.63
95.91
%
2.17
266
1977
39
171
2.30
5.53
1.5
1.6
35.40
33.62
%
0.09
25
111
84
492
1.73
5.28
1.9
3.3
1.51
3.07
ratio
1.15
41
267
144
966
1.52
5.23
2.1
2.2
—
—
—
0
0
43
202
2.15
5.19
1.5
2.4
75.30
73.97
%
0.24
43
197
51
256
2.01
5.18
2.0
2.1
0.92
0.91
%
0.05
37
158
52
264
1.99
5.13
1.1
1.1
—
—
—
0
0
25
92
2.73
5.10
1.5
2.2
30.64
31.11
%
0.05
25
92
91
552
1.67
5.05
2.1
3.4
37.35
42.30
mg/l
0.31
75
469
91
553
1.67
5.02
2.2
3.4
45.36
64.32
mg/l
0.76
76
469
168
1176
1.46
4.96
8.9
7.3
24.06
24.46
mmol/l
0.77
161
1123
64
354
1.83
4.90
1.5
1.6
—
—
—
0
0
54
284
1.92
4.83
1.4
1.4
—
—
nmol/l
—
0
0
110
714
1.56
4.67
1.9
2.2
3.72
3.71
g/l
0.01
102
666
110
714
1.56
4.67
1.9
2.2
4.08
4.27
g/l
1.76
102
665
188
1362
1.41
4.62
10.7
11.1
94.59
93.92
%
1.28
188
1356
227
1698
1.37
4.61
1.3
1.3
40.60
50.12
au/ml
—
10
106
148
1028
1.46
4.57
1.5
1.7
7.02
12.68
u/ml
1.72
28
269
240
1814
1.35
4.56
2.5
2.4
21.08
21.02
au/ml
0.00
23
224
21
75
2.81
4.55
1.1
1.3
—
—
—
0
0
27
112
2.42
4.38
1.1
1.1
—
—
—
0
0
57
319
1.80
4.25
1.4
1.5
—
—
—
0
0
57
319
1.80
4.25
1.4
1.5
—
—
—
0
0
57
319
1.80
4.25
1.4
1.5
—
—
—
0
0
57
319
1.80
4.25
1.4
1.5
—
—
—
0
0
126
862
1.48
4.22
8.1
5.3
1.60
1.64
%
0.19
121
810
73
442
1.67
4.14
1.0
1.1
2.00
2.13
eliau/ml
0.08
21
215
116
787
1.49
4.06
8.6
5.6
0.79
0.88
%
1.89
110
737
93
602
1.56
4.04
9.6
6.4
1.18
1.24
mmol/l
0.44
76
518
39
196
2.00
4.02
1.1
1.0
—
—
—
0
0
45
238
1.91
4.02
2.6
2.7
—
—
—
0
0
115
781
1.49
4.01
2.4
3.6
249.53
376.04
mg/l
0.89
51
378
58
333
1.76
3.99
2.2
1.5
66.78
64.62
mmol/l
0.11
41
281
160
1163
1.40
3.90
13.0
11.6
15.91
16.25
%
0.74
154
1119
73
451
1.64
3.86
3.3
3.7
2.31
2.20
mmol/l
0.14
53
282
14
44
3.19
3.77
2.2
2.1
1.16
1.34
umol/l
1.05
14
29
138
989
1.42
3.67
2.2
2.5
21.29
20.71
s
0.28
120
871
71
444
1.61
3.60
3.8
3.4
6.98
7.85
pmol/l
0.41
71
444
86
568
1.53
3.47
3.5
3.9
64.81
62.89
%
0.40
86
550
33
167
1.99
3.39
1.1
1.1
—
—
—
0
0
500
4291
1.20
3.33
1.7
1.5
—
—
—
0
0
17
65
2.63
3.30
2.8
1.7
38.85
41.50
g/l
1.16
17
65
19
77
2.48
3.29
2.1
2.4
77.16
75.31
ug/l
0.02
19
77
6
7
8.59
3.26
1.2
1.0
273.00
325.14
u/ml
—
6
7
879
7921
1.16
3.25
1.6
1.6
—
—
—
0
0
91
619
1.49
3.22
1.8
2.3
9.85
10.33
g/l
0.61
83
567
304
2491
1.25
3.19
3.8
4.2
33.09
31.35
%
1.80
226
1779
27
130
2.09
3.18
1.3
1.3
38.60
68.53
%
—
5
17
24
111
2.17
3.12
1.1
1.0
—
—
—
0
0
37
201
1.85
3.12
1.2
1.1
—
—
—
0
0
236
1886
1.27
3.07
2.8
2.2
6.01
6.12
ph
1.11
155
1193
22
99
2.23
3.06
1.1
1.1
31.00
314.63
ng/l
—
8
22
226
2812
0.79
3.02
1.4
1.6
3.34
3.49
mmol/l
1.08
144
1894
22
101
2.19
2.93
1.2
1.1
—
0.06
g/l
—
0
6
54
334
1.63
2.92
1.4
1.4
0.63
5.86
nmol/l
0.49
54
323
91
633
1.45
2.91
1.8
1.6
1303.79
1290.35
e6/l
0.01
70
487
63
406
1.56
2.88
2.4
2.5
40.73
42.66
iu/ml
—
6
31
54
337
1.61
2.83
1.6
1.5
61.73
69.64
mu/l
0.12
48
299
21
96
2.20
2.83
1.0
1.1
0.23
10.58
u/ml
0.70
11
57
98
696
1.42
2.81
1.5
2.3
11.67
11.06
mg/l
0.32
90
658
29
151
1.93
2.80
2.1
3.1
1020.83
936.76
u/ml
0.13
29
151
55
346
1.60
2.80
1.4
1.4
0.16
0.35
nmol/l
—
7
21
85
591
1.45
2.74
1.6
1.6
—
—
—
0
0
33
181
1.83
2.73
1.1
1.1
—
—
—
0
0
89
625
1.44
2.72
1.7
1.5
17.34
33.02
e6/l
0.54
62
455
86
602
1.44
2.68
2.7
2.4
—
—
—
0
0
9
230
0.39
2.67
12.3
16.8
544.78
812.59
nmol/l
—
9
225
12
41
2.93
2.61
1.0
1.6
11.31
782359.32
nmol/l
—
7
34
10
30
3.34
2.60
2.1
1.5
—
—
—
0
0
7
15
4.68
2.59
1.0
1.2
—
—
—
0
0
97
699
1.40
2.59
11.7
8.8
—
—
—
0
0
31
172
1.81
2.50
1.5
2.0
0.78
1.90
u/ml
—
8
58
208
1682
1.26
2.49
3.1
3.6
4.64
4.61
pmol/l
0.12
189
1522
8
21
3.82
2.46
1.0
1.0
—
—
—
0
0
316
3707
0.83
2.42
1.6
1.9
3.62
3.57
ratio
0.27
240
2769
7
17
4.13
2.36
1.0
1.1
—
—
—
0
0
36
213
1.70
2.36
1.3
1.2
—
—
—
0
0
123
938
1.33
2.33
2.1
1.8
—
—
—
0
0
57
380
1.51
2.31
1.2
1.3
60.31
31.41
u/l
0.35
52
327
21
105
2.01
2.30
2.4
4.3
—
—
—
0
0
22
112
1.97
2.30
1.5
1.7
—
—
—
0
0
81
579
1.41
2.30
3.6
3.5
8.95
8.63
kpa
0.94
81
567
46
293
1.58
2.28
1.5
1.4
0.19
0.24
nmol/l
0.28
39
229
33
193
1.72
2.26
1.1
1.2
—
—
—
0
0
64
441
1.46
2.22
3.2
2.8
1.35
1.49
mmol/l
0.90
64
422
15
67
2.25
2.17
3.6
2.5
—
—
—
0
0
11
42
2.63
2.14
1.6
3.3
—
—
—
0
0
10
237
0.42
2.10
15.8
21.9
1291.80
1412.38
nmol/l
—
10
232
20
102
1.97
2.10
1.6
5.6
7413.00
69.40
mg/l
0.47
14
77
123
956
1.30
2.07
3.4
2.9
1.02
1.02
ratio
0.67
117
866
12
50
2.41
2.02
1.2
2.8
—
—
—
0
0
14
63
2.23
2.01
1.0
1.7
—
—
—
0
0
52
353
1.48
1.97
3.2
2.9
7.08
7.28
mmol/l
0.24
52
339
21
113
1.86
1.91
1.0
1.1
—
—
—
0
0
39
251
1.56
1.89
1.5
1.4
—
—
—
0
0
84
630
1.34
1.84
1.3
1.2
20.80
45.02
u/ml
1.15
12
60
65
469
1.40
1.81
1.4
1.4
20.68
20.59
u/l
0.01
56
398
294
3371
0.86
1.75
1.2
1.3
—
—
—
0
0
6
18
3.34
1.74
1.7
1.4
363.67
349.06
umol/24h
—
6
18
32
203
1.58
1.68
1.2
1.1
104.66
112.57
pmol/l
0.41
32
203
47
326
1.45
1.65
1.9
1.8
—
—
—
0
0
155
1282
1.22
1.60
2.3
2.9
143.74
152.42
ng/l
0.11
136
1144
17
91
1.87
1.60
1.8
1.6
—
—
—
0
0
109
868
1.27
1.58
1.4
1.3
—
—
—
0
0
23
137
1.68
1.55
1.3
1.4
138.32
138.16
nmol/l
0.01
23
137
21
122
1.73
1.54
1.8
1.4
126.33
165.54
mmol/24h
2.46
21
122
144
1190
1.22
1.52
2.1
2.0
—
—
—
0
0
75
972
0.77
1.50
1.5
1.6
—
—
—
0
0
141
1165
1.22
1.49
1.5
1.5
6.96
8.27
u/l
0.97
116
939
188
2203
0.84
1.49
1.5
1.6
951.21
994.79
mu/l
0.28
159
1852
61
453
1.35
1.48
1.5
1.6
590.24
347.03
mu/l
0.71
49
368
17
94
1.81
1.47
1.2
1.1
—
—
—
0
0
17
94
1.81
1.47
1.1
1.0
—
—
—
0
0
37
254
1.46
1.40
1.1
1.2
38.62
40.70
mg/l
0.12
30
208
98
786
1.26
1.38
1.3
1.1
—
—
—
0
0
73
936
0.77
1.37
1.4
1.5
1.35
1.26
mm
0.89
56
662
25
158
1.59
1.37
1.5
1.4
—
—
—
0
0
66
503
1.32
1.37
2.7
2.3
131.89
131.72
g/l
0.02
45
401
20
323
0.62
1.36
2.6
4.2
55.95
28.64
u/ml
0.66
20
317
37
256
1.45
1.36
4.1
5.1
45.09
73.49
u/ml
0.38
15
79
10
47
2.13
1.33
1.0
1.1
—
—
—
0
0
10
47
2.13
1.33
2.2
2.4
—
—
—
0
0
75
950
0.78
1.30
1.5
1.5
—
—
—
0
0
39
276
1.42
1.28
1.2
1.1
—
—
titre
—
0
0
5
18
2.78
1.28
1.0
1.0
—
—
—
0
0
2196
22392
0.91
1.27
3.9
3.9
1.40
1.29
mmol/l
7.48
2073
21172
11
55
2.00
1.27
1.2
1.0
—
—
—
0
0
11
55
2.00
1.27
1.2
1.0
—
—
—
0
0
11
55
2.00
1.27
1.2
1.0
—
—
—
0
0
34
235
1.45
1.27
1.3
1.1
—
—
—
0
0
82
652
1.27
1.26
1.2
1.1
—
—
—
0
0
82
652
1.27
1.26
1.2
1.1
—
—
—
0
0
198
1718
1.16
1.25
1.2
1.2
—
—
—
0
0
8
36
2.23
1.24
1.0
1.0
—
—
—
0
0
27
179
1.51
1.23
1.1
1.9
—
—
—
0
0
15
85
1.77
1.23
3.7
2.6
—
—
—
0
0
12
63
1.91
1.22
1.3
1.4
—
—
—
0
0
18
108
1.67
1.22
2.9
1.8
—
—
—
0
0
52
391
1.34
1.21
3.6
3.7
—
—
—
0
0
7
141
0.50
1.20
3.0
2.4
147.86
151.59
nmol/l
—
7
126
151
1287
1.18
1.20
1.4
1.3
184.93
225.65
miu/ml
0.60
53
616
23
149
1.55
1.17
2.8
2.6
753.50
626.11
ml
0.80
18
101
6
128
0.47
1.16
2.0
2.6
46.17
49.44
umol/l
—
6
116
691
6481
1.09
1.15
4.3
4.3
11.39
8.97
mg/mmol
0.51
465
4162
2355
23905
0.90
1.14
4.7
5.0
2.63
2.80
mmol/l
21.70
2241
22753
19
118
1.61
1.14
1.6
3.3
85.55
120.24
umol/l
0.48
11
63
145
1240
1.18
1.12
2.0
2.9
56.70
59.76
u/ml
0.05
138
1198
24
160
1.50
1.09
1.1
1.2
—
—
—
0
0
110
1307
0.84
1.08
1.0
1.1
0.56
0.65
ratio
—
10
125
52
400
1.31
1.06
2.1
2.0
4.58
5.19
mmol/24h
0.67
47
357
13
74
1.76
1.06
1.4
1.1
—
—
—
0
0
116
1366
0.84
1.04
1.0
1.1
1.44
1.51
g/l
2.09
116
1366
9
46
1.96
1.03
1.1
1.2
—
—
—
0
0
20
130
1.54
1.02
1.6
2.8
23.75
263.16
ug/l
0.68
20
116
804
7623
1.08
1.02
3.5
3.6
8.19
8.21
mmol/l
0.06
706
6660
28
198
1.42
0.97
1.4
1.3
0.68
0.63
ratio
0.19
15
111
0
31
0.00
0.96
0.0
4.0
—
43.15
—
0
24
678
6404
1.08
0.95
3.6
3.6
60.62
52.22
mg/l
0.38
460
4177
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
122
1417
0.85
0.95
1.6
1.5
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
0.01
1.04
u/ml
1.62
11
62
16
101
1.59
0.93
4.2
2.5
—
—
—
0
0
6
27
2.22
0.93
9.2
6.3
3.30
6.26
mmol/l
—
6
27
90
753
1.20
0.93
1.1
1.1
3.12
1.11
u/ml
0.41
37
337
20
290
0.69
0.90
1.9
2.5
21.27
21.62
nmol/l
0.06
20
277
38
288
1.32
0.89
2.1
2.2
—
—
—
0
0
8
42
1.91
0.88
1.0
1.0
9.44
6.47
u/ml
—
8
42
16
241
0.66
0.87
1.4
1.3
148.12
177.43
pmol/l
0.71
16
241
8
43
1.86
0.87
1.9
3.4
3.62
4.74
ug/l
—
8
43
2333
23626
0.92
0.84
4.3
4.5
1.40
1.44
mmol/l
4.18
2219
22461
54
435
1.25
0.82
1.5
1.6
—
—
—
0
0
27
197
1.37
0.82
1.1
1.0
—
—
—
0
0
16
105
1.53
0.81
1.1
1.2
—
—
—
0
0
107
1235
0.86
0.80
1.4
1.5
66.52
59.19
ug/l
0.72
92
1034
201
1813
1.12
0.79
1.5
1.4
20.19
22.02
iu/l
0.43
177
1527
7
38
1.84
0.73
1.3
1.0
—
—
—
0
0
29
219
1.33
0.73
1.2
1.1
—
—
—
0
0
7
39
1.80
0.72
1.4
1.3
3.09
3.35
mmol/l
—
7
34
91
784
1.17
0.72
1.1
1.1
6.77
6.13
u/ml
0.11
43
443
11
68
1.62
0.71
1.6
1.5
9.41
10.13
mmol/l
0.14
11
68
48
588
0.81
0.71
1.3
1.4
2.89
3.92
ug/l
0.91
48
541
5
26
1.92
0.70
1.0
1.2
—
—
—
0
0
57
472
1.21
0.70
1.2
1.2
—
—
—
0
0
23
169
1.36
0.69
1.7
2.8
43.38
44.05
%
0.07
14
81
9
59
1.53
0.68
1.2
1.1
—
—
—
0
0
2256
22282
1.07
0.66
4.4
4.4
5.72
5.79
mmol/l
1.80
2117
20910
24
317
0.75
0.66
1.1
1.2
—
—
—
0
0
29
223
1.30
0.66
1.1
1.1
0.29
2.81
u/ml
—
10
81
229
2106
1.10
0.65
1.2
1.2
125.71
143.53
u/ml
0.17
60
795
10
62
1.62
0.65
1.0
1.1
—
—
—
0
0
10
62
1.62
0.65
1.0
1.1
—
—
—
0
0
10
62
1.62
0.65
1.0
1.1
—
—
—
0
0
54
450
1.20
0.64
1.4
1.3
3.66
4.52
u/ml
0.41
29
206
98
862
1.14
0.61
1.1
1.1
0.63
2.34
u/ml
2.99
44
459
29
226
1.29
0.61
1.2
1.3
0.02
2.48
u/ml
2.32
14
118
14
96
1.46
0.61
1.5
2.7
0.24
0.18
e9/l
—
8
49
2348
23714
0.94
0.61
4.4
4.6
4.51
4.70
mmol/l
18.95
2241
22655
34
271
1.26
0.61
1.3
1.6
275.42
282.54
mosm/kgh2o
1.14
26
206
30
236
1.27
0.59
1.5
2.6
1.14
1.65
g/24h
0.51
13
152
2215
21886
1.06
0.59
5.2
5.4
37.01
38.08
mmol/mol
9.23
2110
20887
85
743
1.15
0.59
1.5
2.2
4.74
3.92
iu/l
0.26
28
332
0
23
0.00
0.58
0.0
1.3
—
30.38
—
0
23
23
175
1.32
0.58
1.3
1.3
76.30
75.71
umol/l
0.07
23
175
5
87
0.57
0.56
2.8
2.2
1.64
2.96
ug/l
—
5
82
58
497
1.17
0.53
2.2
1.9
—
—
—
0
0
14
193
0.72
0.53
1.7
3.5
—
—
—
0
0
13
91
1.43
0.53
1.4
1.6
0.23
0.03
estimate
0.38
13
91
14
101
1.39
0.49
3.7
2.6
16.17
16.89
%
0.35
14
101
28
225
1.25
0.49
1.0
1.0
1.28
1.35
u/ml
—
7
60
38
454
0.83
0.49
4.3
3.3
21.79
24.08
mg/l
0.20
25
303
22
172
1.28
0.48
1.6
1.6
5.84
6.37
mmol/l
1.06
16
126
17
221
0.77
0.46
1.2
1.2
—
—
—
0
0
156
1680
0.92
0.42
1.7
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
10.2
—
155.91
—
0
11
5
36
1.39
0.38
1.6
1.6
—
—
—
0
0
19
152
1.25
0.37
1.7
1.6
—
—
—
0
0
70
630
1.11
0.36
1.1
1.1
—
—
—
0
0
5
77
0.65
0.35
1.0
1.0
7.74
41.60
iu/ml
—
5
77
18
144
1.25
0.35
1.4
1.4
—
—
—
0
0
982
10022
0.97
0.34
2.0
1.9
1.54
1.40
mmol/l
3.55
862
8761
6
45
1.33
0.33
1.7
1.2
—
—
—
0
0
14
109
1.29
0.33
3.4
2.4
7.64
8.07
mmol/l
0.20
14
109
606
5894
1.04
0.32
4.5
4.6
1.81
1.96
ug/l
0.54
567
5404
92
847
1.09
0.32
2.4
3.2
—
—
—
0
0
62
562
1.11
0.30
1.1
1.1
8.71
16.61
au/ml
1.12
14
160
62
565
1.10
0.28
1.0
1.1
0.48
0.28
u/ml
0.18
18
180
81
748
1.09
0.28
1.0
1.1
1.90
1.87
u/ml
0.01
39
380
239
2493
0.95
0.27
2.4
2.4
12.61
13.32
nmol/l
0.83
223
2314
65
595
1.09
0.27
1.0
1.1
6.46
5.11
u/ml
0.22
27
266
24
279
0.86
0.27
2.0
2.8
—
—
—
0
0
8
66
1.21
0.26
3.1
2.2
1.95
2.85
mmol/l
—
8
60
456
4435
1.03
0.26
2.0
1.9
—
—
—
0
0
12
148
0.81
0.24
1.1
1.0
—
—
—
0
0
69
638
1.08
0.24
1.0
1.1
3.14
3.59
u/ml
0.14
30
320
16
134
1.20
0.22
1.3
2.1
1.00
1.94
u/field
—
9
84
25
219
1.14
0.22
1.2
1.2
—
—
—
0
0
26
229
1.14
0.21
1.4
1.4
1.61
1.46
nmol/l
0.39
26
210
10
124
0.81
0.21
1.7
2.6
2250.70
2048.40
ml
—
10
115
13
107
1.22
0.21
1.2
1.6
73.46
101.59
nmol/24h
0.97
13
107
5
42
1.19
0.21
1.0
1.3
65.00
67.57
ug/l
—
5
42
0
10
0.00
0.21
0.0
2.9
—
0.55
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
5.2
—
444.50
—
0
12
20
173
1.16
0.21
1.5
1.4
2934.25
1953.05
e6/l
0.32
12
115
28
249
1.13
0.20
2.0
1.5
1.03
1.30
promille
0.39
20
201
142
1485
0.95
0.20
1.6
1.7
311.09
286.52
mu/l
0.40
129
1349
6
48
1.25
0.20
14.3
6.5
7.40
5.22
kpa
—
6
48
11
133
0.83
0.19
2.1
1.6
1.24
1.29
nmol/l
0.06
11
103
7
61
1.15
0.17
1.3
1.2
—
—
—
0
0
7
61
1.15
0.17
3.4
2.0
—
—
—
0
0
17
148
1.15
0.17
6.7
7.4
7.17
133.59
ug/l
0.61
11
100
351
3589
0.97
0.16
2.7
2.9
0.59
0.69
ug/l
2.74
208
2012
8
72
1.11
0.16
1.1
1.1
—
—
—
0
0
46
428
1.08
0.16
1.2
1.2
—
—
—
0
0
17
149
1.14
0.15
1.6
1.4
18127.50
25699.88
e6/l
—
8
80
24
216
1.11
0.15
1.0
1.1
0.25
1.85
u/ml
—
7
51
22
245
0.90
0.15
3.5
3.4
0.67
0.79
nmol/l
1.44
12
203
9
82
1.10
0.15
1.0
1.3
—
—
—
0
0
7
87
0.80
0.14
3.1
2.0
19.33
15.51
umol/l
—
7
87
160
1551
1.03
0.14
1.1
1.1
—
—
—
0
0
50
473
1.06
0.12
1.2
1.2
—
—
—
0
0
12
137
0.88
0.12
3.3
3.2
45.42
45.66
%
0.02
12
137
12
137
0.88
0.12
6.5
6.4
9.33
7.99
%
0.45
12
137
162
1579
1.03
0.11
2.0
2.4
—
—
—
0
0
11
125
0.88
0.10
1.4
1.4
70.73
73.69
%
0.24
11
119
5
45
1.11
0.09
1.4
1.4
—
—
—
0
0
48
457
1.05
0.09
1.1
1.1
21.44
1201.93
iu/ml
—
8
115
197
2011
0.98
0.09
2.0
2.2
—
—
—
0
0
51
533
0.96
0.09
1.3
1.3
—
—
—
0
0
11
97
1.13
0.09
1.4
1.3
26.73
28.56
s
0.56
11
97
7
64
1.09
0.08
1.0
1.0
4.36
7.30
mg/g
—
7
64
44
460
0.96
0.08
3.0
2.6
51.84
114.89
ug/min
1.37
28
285
7
66
1.06
0.08
1.0
1.0
—
—
—
0
0
54
521
1.04
0.07
1.5
2.7
1.03
0.86
nmol/l
0.80
49
455
11
122
0.90
0.07
1.4
1.4
644.09
380.31
mu/l
0.82
11
116
197
2001
0.98
0.07
2.0
2.3
—
—
—
0
0
17
183
0.93
0.06
1.8
1.6
0.52
0.48
e9/l
0.32
17
183
196
1988
0.98
0.06
1.9
2.2
—
—
—
0
0
13
119
1.09
0.06
2.7
3.1
—
—
—
0
0
18
168
1.07
0.06
1.4
1.2
11.56
8.43
mm/h
1.02
18
168
199
2017
0.99
0.06
2.0
2.3
—
—
—
0
0
144
1419
1.02
0.05
2.6
3.2
—
—
—
0
0
302
3046
0.99
0.04
1.7
1.8
—
—
—
0
0
11
101
1.09
0.04
1.3
2.1
60.56
107.28
ng/l
2.85
11
101
12
112
1.07
0.03
1.2
1.3
—
—
—
0
0
84
852
0.99
0.02
1.9
1.9
200.80
209.41
pmol/l
0.44
79
810
25
259
0.96
0.02
1.1
1.1
22.23
16.16
u/ml
—
7
113
61
620
0.98
0.02
1.6
1.5
0.47
0.42
nmol/l
0.25
48
494
188
1867
1.01
0.02
2.0
2.3
—
—
—
0
0
31
304
1.02
0.00
2.5
1.8
—
—
—
0
0
31
304
1.02
0.00
1.6
1.6
7.69
7.57
mmol/l
0.12
31
294
18
185
0.97
0.00
2.1
2.7
—
—
—
0
0
33
329
1.00
0.00
2.4
2.3
—
—
—
0
0
19
194
0.98
0.00
1.9
2.5
25.23
30.19
mg/l
0.29
13
133
10
103
0.97
0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
30.87
—
0
6
8
81
0.99
-0.00
1.1
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
2800.00
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
36.93
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
69.37
—
0
8
0
7
0.00
-0.00
0.0
3.1
—
2.04
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
1068.50
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
3.09
—
0
9

Mortality – FinRegistry

Association

Association between endpoint K11_CD_STRICT2 and mortality.

Females

Parameter HR [95% CI] p-value
K11_CD_STRICT2 1.165 [1.01, 1.34] 0.033
Birth year 0.998 [0.99, 1.01] 0.711

During the follow-up period (1.1.1998 — 31.12.2019), 291 out of 5295 females with K11_CD_STRICT2 died.

Males

Parameter HR [95% CI] p-value
K11_CD_STRICT2 1.13 [0.99, 1.29] 0.074
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 374 out of 5115 males with K11_CD_STRICT2 died.

Mortality risk

Mortality risk for people of age

years, who have K11_CD_STRICT2.

N-year risk Females Males
1 0.11% 0.199%
5 0.842% 1.372%
10 1.983% 3.277%
15 3.736% 6.183%
20 6.677% 10.509%

Relationships between endpoints

Index endpoint: K11_CD_STRICT2 – Crohn disease (strict definition, require KELA, min 2 HDR)

GWS hits: 16

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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