Hypermetropia

H7_HYPERMETRO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H52.0
  • Hospital discharge: ICD-9 3670
  • Hospital discharge: ICD-8 37001
  • Cause of death: ICD-10 H52.0
  • Cause of death: ICD-9 3670
  • Cause of death: ICD-8 37001

2 out of 7 registries used, show all original rules.

3472

4. Check minimum number of events

None

3472

5. Include endpoints

None

3472

6. Filter based on genotype QC (FinnGen only)

3111

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H52
Name in latin
Hyperopia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 43985 23830 20105
Only index persons 33198 18331 14867
Unadjusted period prevalence (%)
Whole population 0.63 0.68 0.56
Only index persons 0.63 0.67 0.57
Median age at first event (years)
Whole population 7.22 7.69 6.59
Only index persons 9.13 10.16 7.86

-FinnGen-

Key figures

All Female Male
Number of individuals 3111 1995 1116
Unadjusted period prevalence (%) 0.64 0.71 0.51
Median age at first event (years) 53.29 51.83 55.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3244
Matched controls
32405
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.4
ICD-10 Finland
Presbyopia
14.4
307.7
351
270
H53.0
ICD-10 Finland
Amblyopia ex anopsia
34.6
307.7
253
79
H52.0
ICD-10 Finland
Hypermetropia
5112.1
307.7
3097
133
H52.2
ICD-10 Finland
Astigmatism
46.4
307.7
397
97
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
45.1
212.7
126
29
H50.0
ICD-10 Finland
Convergent concomitant strabismus
800.2
156.7
153
*
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
130.0
124
*
H50.52
ICD-10 Finland
Exophoria
25.5
124.2
87
35
H50.30
ICD-10 Finland
Intermittent esotropy
394.1
115.2
115
*
CHC05
NOMESCO Finland
Iridotomy
9.0
91.7
114
130
H50.31
ICD-10 Finland
Intermittent exotropia
141.8
78.3
83
6
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
77.4
74
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
380.6
75.0
75
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
69.6
688
3470
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
+∞
66.9
64
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.1
64.1
846
4753
XCK00
NOMESCO Finland
Perimetry
3.5
63.1
232
703
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
62.7
60
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
61.5
1313
8653
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.6
56.5
360
1484
H50.51
ICD-10 Finland
Esophoria
75.5
46.0
52
7
H50.2
ICD-10 Finland
Vertical strabismus
86.3
45.9
51
6
H54.7
ICD-10 Finland
Unspecified visual loss
8.6
42.9
55
65
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
11.8
42.0
43
37
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
41.4
264
1084
H40.0
ICD-10 Finland
Glaucoma suspect
2.5
41.3
269
1116
H25.0
ICD-10 Finland
Senile incipient cataract
2.8
40.9
217
812
P85
ICPC
Mental retardation
10.1
37.1
42
42
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
36.5
35
*
H53.2
ICD-10 Finland
Diplopia
4.0
36.1
105
271
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.0
35.6
104
269
R51.80
ICD-10 Finland
Headache
1.8
34.9
600
3594
3670A
ICD-9 Finland
Disorders of refraction and accommodation, Hypermetropia
+∞
32.3
31
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
319.8
31.9
32
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
31.9
869
5894
ZXA10
NOMESCO Finland
Bilateral
1.8
30.7
560
3402
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
104.2
28.7
31
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
28.6
251
1184
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
28.2
353
1900
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.1
26.3
272
1366
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
25.5
290
1507
F83
ICD-10 Finland
Mixed specific developmental disorders
4.1
24.3
66
162
CHD00
NOMESCO Finland
Laser trabeculoplasty
5.3
24.1
48
91
H51.1
ICD-10 Finland
Convergence insufficiency and excess
241.5
23.7
24
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.2
22.6
30
37
H52.5
ICD-10 Finland
Disorders of accommodation
120.8
22.6
24
*
UDC00
NOMESCO Finland
Ear microscopy
2.0
22.3
252
1306
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
22.1
262
1382
R42
ICD-10 Finland
Dizziness and giddiness
1.6
22.0
644
4387
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
22.0
314
1760
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
21.8
358
2095
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.1
20.5
203
1002
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
20.2
667
4659
SPAT1301
SPAT
No procedures
1.5
19.9
922
6902
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
31.4
19.2
25
8
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
19.0
110
430
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
18.5
614
4285
H50.9
ICD-10 Finland
Strabismus, unspecified
17.6
18.2
28
16
H26.4
ICD-10 Finland
After-cataract
1.9
17.7
236
1292
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
28.9
17.4
23
8
R62.0
ICD-10 Finland
Delayed milestone
3.4
17.3
62
185
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.2
17.1
69
222
WX704
NOMESCO Finland
Intubation
1.8
16.8
239
1336
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
16.8
236
1314
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
6.1
16.8
29
48
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
16.7
1274
10346
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
16.7
16
*
3503
FHL
Single muscle retroposition
+∞
16.7
16
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.1
16.5
167
832
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
16.2
2285
20421
XA800
NOMESCO Finland
Neuropsychological investigation
2.1
16.1
154
751
Z3229
NOMESCO Finland
Other healthcare associate professional
1.8
16.0
242
1380
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
15.9
355
2255
M79.6
ICD-10 Finland
Pain in limb
1.4
15.9
1271
10376
H52.1
ICD-10 Finland
Myopia
2.9
15.9
74
259
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
15.9
568
4017
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
3.6
15.8
52
147
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
15.6
15
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
15.6
15
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
5.0
15.4
33
67
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
15.2
735
5502
A02BC05
ATC
esomeprazole; systemic
1.4
15.1
1058
8436
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
15.1
727
5438
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
15.0
423
2838
Z2445
NOMESCO Finland
Psychologist
2.0
15.0
171
889
Z31.5
ICD-10 Finland
Genetic counselling
1.9
14.7
180
958
AA1AD
NOMESCO Finland
CT of head and brain
1.4
14.7
697
5197
WX720
NOMESCO Finland
Own respiration
2.1
14.6
144
711
E0000UV, ,
ATC
1.3
14.5
1291
10672
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
150.5
14.5
15
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
14.5
1100
8874
N02AX02
ATC
tramadol; systemic, rectal
1.4
14.3
1086
8753
WX402
NOMESCO Finland
General anaesthesia
1.4
14.2
672
5004
602
Kela drug reimbursment
Children's severe malnutrition
3.6
14.2
46
129
TAB00
NOMESCO Finland
Lumbar puncture
2.1
14.1
140
692
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
13.8
329
2120
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
13.8
434
2983
H47.2
ICD-10 Finland
Optic atrophy
6.5
13.6
22
34
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.5
13.6
82
329
SPAT1263
SPAT
Sampling
1.3
13.3
1223
10116
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
13.2
359
2386
XCH00
NOMESCO Finland
Eye pressure measurement
2.1
13.1
118
563
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.7
13.0
249
1518
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
12.8
146
759
N03AX12
ATC
[U] gabapentin; oral
1.5
12.7
398
2729
N02BE01
ATC
paracetamol; systemic, rectal
1.4
12.7
2641
24508
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
12.5
414
2874
L04AD01
ATC
ciclosporin; systemic
2.7
12.4
66
249
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.5
12.4
41
117
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.9
12.1
148
789
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
12.1
193
1118
C07AA05
ATC
propranolol; systemic
1.4
12.0
568
4215
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
12.0
1319
11138
XKC03
NOMESCO Finland
Water cystometry
2.4
11.9
80
338
R03AC02
ATC
salbutamol; inhalant
1.3
11.8
1638
14257
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
11.6
290
1890
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
11.5
629
4787
127
Kela drug reimbursment
Transplant complication
2.8
11.5
56
202
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
11.5
11
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
11.5
11
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.6
11.4
37
104
B05DA
ATC
Isotonic solutions
4.4
11.4
28
64
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
11.4
813
6450
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
11.4
1587
13801
N05BA09
ATC
clobazam; oral
3.9
11.3
33
86
H57.1
ICD-10 Finland
Ocular pain
2.0
11.3
122
623
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
11.3
250
1582
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
11.3
141
758
M03BX02
ATC
tizanidine; oral
1.3
11.2
1649
14426
G44.2
ICD-10 Finland
Tension-type headache
1.5
11.1
387
2709
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
11.0
849
6807
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
10.9
259
1666
Z94.0
ICD-10 Finland
Kidney transplant status
3.2
10.9
42
132
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.0
10.9
30
75
N06AX11
ATC
mirtazapine; oral
1.3
10.8
892
7218
137
Kela drug reimbursment
Uraemia requiring dialysis
3.9
10.8
31
80
L17
ICPC
Foot/toe symptom/complaint
1.3
10.8
905
7341
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
10.7
699
5463
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
10.7
352
2437
G47.3
ICD-10 Finland
Sleep apnoea
1.4
10.7
555
4183
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
10.6
370
2590
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
60.1
10.6
12
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.8
10.6
155
876
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.6
10.6
61
240
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.2
10.5
27
64
3507
FHL
Retroposition and resection
110.3
10.4
11
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
10.4
10
*
J02AC01
ATC
fluconazole; systemic
1.3
10.4
1021
8456
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
10.3
717
5652
37929
ICD-8 Finland
Blindness, one eye, specifically defined
32.6
10.3
13
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
10.3
105
526
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
10.3
155
884
R35
ICD-10 Finland
Polyuria
1.8
10.3
163
944
B03XA01
ATC
erythropoietin; parenteral
3.8
10.2
30
79
M25.5
ICD-10 Finland
Pain in joint
1.3
10.2
923
7556
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
10.1
185
1114
M54.5
ICD-10 Finland
Low back pain
1.3
10.1
1001
8288
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.4
10.1
67
282
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
10.0
864
7022
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.1
10.0
91
437
H50.8
ICD-10 Finland
Other specified strabismus
40.1
10.0
12
*
A11CC03
ATC
alfacalcidol; systemic
2.4
9.9
63
260
N05CF01
ATC
zopiclone; oral
1.3
9.9
741
5903
N02BF01
ATC
gabapentin; oral
1.5
9.8
270
1800
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.7
545
4152
N06AX21
ATC
duloxetine; oral
1.5
9.7
309
2125
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
9.7
714
5673
SPAT1310
SPAT
Counselling related to known health issue
1.3
9.7
915
7524
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.2
9.6
76
345
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
9.6
268
1790
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
9.6
370
2641
H02AB06
ATC
prednisolone; systemic
1.3
9.6
1228
10492
H53.3
ICD-10 Finland
Other disorders of binocular vision
4.4
9.5
23
52
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
9.5
163
965
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.5
1084
9126
M54.2
ICD-10 Finland
Cervicalgia
1.6
9.5
214
1361
S06.0
ICD-10 Finland
Concussion
1.5
9.5
322
2243
ZXD20
NOMESCO Finland
Day surgery
1.5
9.4
317
2206
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
4.2
9.4
24
57
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.1
9.3
81
383
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.5
9.3
55
220
R52.9
ICD-10 Finland
Pain, unspecified
1.5
9.2
280
1906
N06AX16
ATC
venlafaxine; oral
1.4
9.2
386
2800
D06
ICPC
Abdominal pain localized other
1.5
9.1
281
1917
G54.0
ICD-10 Finland
Brachial plexus disorders
2.2
9.0
75
348
Q21.10
ICD-10 Finland
Persistent ostium secundum
3.2
9.0
35
111
H01
ICPC
Ear pain/earache
1.4
9.0
427
3163
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
9.0
339
2410
UKC02
NOMESCO Finland
Cystoscopy
1.5
9.0
326
2301
N06AA09
ATC
amitriptyline; systemic
1.6
8.9
210
1349
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
8.9
309
2159
N17
ICPC
Vertigo/dizziness
1.4
8.9
351
2516
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.7
8.9
155
923
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.8
2257
20817
A02BC02
ATC
pantoprazole; systemic
1.3
8.8
1803
16203
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.7
683
5465
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.6
461
3481
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
7.6
8.6
19
25
F29
ICPC
Eye symptom/complaint other
1.5
8.6
321
2278
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.1
8.5
81
397
RL140, ,
NOMESCO Finland
6.4
8.5
21
33
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.7
8.4
143
845
H03AA01
ATC
levothyroxine sodium; systemic
1.3
8.4
568
4445
UJF32
NOMESCO Finland
Coloscopy
1.3
8.4
603
4760
J01DB01
ATC
cefalexin; oral
1.3
8.4
2456
22940
XQ845
NOMESCO Finland
Dermatoscopy
2.4
8.4
53
219
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
12.8
8.4
14
11
H47.3
ICD-10 Finland
Other disorders of optic disc
4.9
8.3
18
37
3504
FHL
Retroposition of two muscles
+∞
8.3
8
*
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
8.3
8
*
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
8.3
8
*
ZXE00
NOMESCO Finland
One hour or less
1.3
8.3
1023
8661
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.6
8.3
47
184
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
8.3
391
2892
K07.60
ICD-10 Finland
Snapping jaw
1.7
8.3
152
919
H01AC01
ATC
somatropin; parenteral
2.9
8.3
37
128
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.4
8.2
53
221
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
3.4
8.2
28
82
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
14.5
8.2
13
9
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.2
8.2
63
284
R01AD58
ATC
fluticasone, combinations; nasal
1.3
8.2
712
5774
C09CA06
ATC
candesartan; oral
1.3
8.1
580
4574
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
1.9
8.1
96
508
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
8.1
618
4918
B05DB
ATC
Hypertonic solutions
3.9
8.1
23
59
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
8.1
1641
14671
R53
ICD-10 Finland
Malaise and fatigue
1.3
8.1
687
5549
101
Kela drug reimbursment
Anterior pituitary hypofunction
2.9
8.1
36
124
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.5
8.1
294
2075
L08
ICPC
Shoulder symptom/complaint
1.3
8.1
593
4697
H02AB09
ATC
hydrocortisone; systemic
2.0
8.1
84
426
XKD00
NOMESCO Finland
Uroflowmetry
1.5
8.0
289
2039
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
7.9
277
1941
Z94.4
ICD-10 Finland
Liver transplant status
4.4
7.9
19
43
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
7.9
418
3152
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.4
7.8
53
226
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.8
7.8
117
668
Z99.2
ICD-10 Finland
Dependence on renal dialysis
8.4
7.8
16
19
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.8
795
6571
Z3231
NOMESCO Finland
Registered nurse
1.3
7.8
739
6053
A12AA04
ATC
calcium carbonate; oral
2.7
7.8
41
155
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
7.7
875
7321
H43.3
ICD-10 Finland
Other vitreous opacities
2.7
7.7
39
144
R5140
NOMESCO Finland
Monitoring the use of the aid
1.5
7.7
247
1700
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
3.0
7.7
32
106
BE00A, ,
NOMESCO Finland
15.0
7.7
12
8
RT150, ,
NOMESCO Finland
3.9
7.7
22
57
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.5
7.7
25
71
R02
ICPC
Shortness of breath/dyspnoea
1.4
7.6
351
2585
A02BC01
ATC
omeprazole; systemic
1.3
7.6
643
5186
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.5
7.6
257
1788
M01AH05
ATC
etoricoxib; oral
1.2
7.6
1632
14642
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
25.0
7.6
10
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
25.0
7.6
10
*
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
11.8
7.6
13
11
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
11.8
7.6
13
11
K59.0
ICD-10 Finland
Constipation
1.7
7.6
145
887
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
8.8
7.5
15
17
R52.2
ICD-10 Finland
Other chronic pain
1.9
7.5
97
529
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.5
561
4449
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.8
7.5
115
661
SPAT1153
SPAT
Removal of sutures
1.3
7.5
738
6070
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.6
7.5
192
1261
J05AB01
ATC
aciclovir; systemic
1.3
7.5
554
4391
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
7.4
1252
10944
N03AG01
ATC
valproic acid; systemic, rectal
1.7
7.4
142
869
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
1.8
7.4
100
554
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
7.3
297
2138
WZC00, ,
SPAT
1.3
7.3
461
3567
R01AD09
ATC
mometasone; nasal
1.2
7.3
1260
11031
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
7.3
7
*
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
7.3
7
*
L04AA06
ATC
mycophenolic acid; systemic
2.3
7.3
54
240
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
10.9
7.3
13
12
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
10.9
7.3
13
12
H54.5
ICD-10 Finland
Severe visual impairment, monocular
4.1
7.3
19
46
H93.1
ICD-10 Finland
Tinnitus
1.6
7.2
167
1070
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
7.2
1133
9820
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
7.2
540
4284
WX892
NOMESCO Finland
Monitored bed care
1.6
7.2
183
1200
N05BA01
ATC
diazepam; systemic, rectal
1.4
7.1
296
2142
K59.09
ICD-10 Finland
Constipation, unspecified
1.6
7.1
171
1108
N06AX05
ATC
trazodone; oral
2.1
7.1
63
302
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
2.5
7.1
41
163
XCW10
NOMESCO Finland
Assessment of vision
2.7
7.1
36
134
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
7.1
381
2880
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
7.0
767
6379
R06.5
ICD-10 Finland
Mouth breathing
1.5
7.0
233
1616
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.1
7.0
61
290
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
7.0
226
1559
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
4.2
7.0
18
43
H47.1
ICD-10 Finland
Papilloedema, unspecified
3.5
7.0
23
66
Z49.2
ICD-10 Finland
Other dialysis
3.5
7.0
23
66
SPAT1097
SPAT
Recording of ECG
1.4
7.0
305
2227
EB1VA, ,
NOMESCO Finland
1.3
6.9
465
3630
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
6.9
1118
9710
J01FF01
ATC
clindamycin; systemic
1.3
6.9
644
5255
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
3.7
6.9
21
57
R1250
NOMESCO Finland
Evaluation of functional capability
2.0
6.9
68
339
KMAK, ,
NOMESCO Finland
1.2
6.9
1306
11528
H27.8
ICD-10 Finland
Other specified disorders of lens
7.5
6.9
15
20
Z49.1
ICD-10 Finland
Extracorporeal dialysis
2.8
6.9
33
119
J01CA04
ATC
amoxicillin; systemic
1.3
6.9
2596
24587
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.6
6.8
164
1061
H53.9
ICD-10 Finland
Visual disturbance, unspecified
1.8
6.8
93
517
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.7
6.8
35
131
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
6.8
183
1215
XQ848
NOMESCO Finland
Dermatological photography
2.0
6.8
74
382
N03AX11
ATC
topiramate; oral
2.0
6.8
66
327
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.2
6.8
55
254
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
3.0
6.8
29
98
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.0
6.7
69
349
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.7
2173
20198
R51.81
ICD-10 Finland
Facial pain NOS
2.0
6.7
66
329
N05BA04
ATC
oxazepam; oral
1.3
6.7
638
5218
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
3.9
6.7
19
49
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.6
6.7
147
932
XX4AW, ,
NOMESCO Finland
3.2
6.7
25
78
H02.3
ICD-10 Finland
Blepharochalasis
1.6
6.7
142
893
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.1
6.7
60
289
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
22.5
6.7
9
*
S01EE01
ATC
latanoprost; ophthalmic
1.7
6.7
121
731
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
2.1
6.6
62
303
R55
ICD-10 Finland
Syncope and collapse
1.4
6.6
252
1794
SPAT1079
SPAT
Echocardiography
3.0
6.6
28
94
SPAT1312
SPAT
General health counselling
1.2
6.6
956
8198
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
6.6
382
2919
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.2
6.6
1036
8962
N05AH04
ATC
quetiapine; oral
1.3
6.6
474
3737
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.5
6.6
191
1290
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.5
6.5
207
1423
SPAT1009
SPAT
Measurement of intraocular pressure
2.6
6.5
35
134
114
Kela drug reimbursment
Glaucoma
1.6
6.5
163
1065
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.2
6.5
54
252
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
6.5
213
1474
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
2.2
6.5
49
220
N05CF02
ATC
zolpidem; oral
1.3
6.5
396
3049
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
6.5
1078
9377
R06AE07
ATC
cetirizine; oral
1.2
6.5
1236
10900
Z3226
NOMESCO Finland
Physiotherapist
1.3
6.5
466
3675
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.5
1783
16285
R00.0
ICD-10 Finland
Tachycardia, unspecified
1.7
6.4
108
639
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
69.9
6.4
7
*
N03AF02
ATC
oxcarbazepine; oral
1.8
6.4
86
476
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
3.2
6.4
24
75
SAA04
NOMESCO Finland
Special examination of mouth
1.5
6.4
190
1290
N95.1
ICD-10 Finland
Menopausal and female climacteric states
1.4
6.4
280
2046
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
6.3
526
4226
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.2
6.3
48
216
B34.9
ICD-10 Finland
Viral infection, unspecified
1.7
6.3
108
642
N06AB04
ATC
citalopram; systemic
1.3
6.3
455
3587
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.4
6.3
237
1684
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
6.3
224
1576
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
6.3
374
2869
N03AX16
ATC
[U] pregabalin
1.3
6.3
516
4140
R4120
NOMESCO Finland
Occupational therapy
1.5
6.3
168
1115
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.3
686
5700
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
6.2
6
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
6.2
6
*
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
6.2
6
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
6.2
147
948
R01AD12
ATC
fluticasone furoate; nasal
1.2
6.2
896
7670
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.6
6.2
149
964
183
Kela drug reimbursment
Lamotrigin and topiramate
2.8
6.2
29
103
OAB50, ,
SPAT
1.5
6.2
189
1288
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
6.2
832
7067
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.2
882
7541
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.7
6.2
115
699
R06.4
ICD-10 Finland
Hyperventilation
2.4
6.2
41
174
D02
ICPC
Abdominal pain epigastric
1.5
6.2
179
1209
R11
ICD-10 Finland
Nausea and vomiting
1.4
6.2
256
1853
P01AB01
ATC
metronidazole; oral, rectal
1.2
6.2
1000
8668
L03
ICPC
Low back symptom/complaint
1.2
6.1
808
6851
F81.0
ICD-10 Finland
Specific reading disorder
2.8
6.1
29
104
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.6
6.1
129
810
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
3.4
6.1
21
62
N92.2
ICD-10 Finland
Excessive menstruation at puberty
3.4
6.1
21
62
R4110
NOMESCO Finland
Physiotherapy
1.2
6.1
701
5857
Z2446
NOMESCO Finland
Social worker
1.5
6.1
203
1411
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
4.1
6.1
16
39
A02BC03
ATC
lansoprazole; oral
1.3
6.1
629
5193
WX002
NOMESCO Finland
Sedation and analgesia
1.3
6.1
433
3410
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
2.9
6.0
27
94
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
1.8
6.0
86
486
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
6.0
254
1844
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.4
6.0
240
1725
R51
ICD-10 Finland
Headache
1.5
6.0
156
1029

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1063
7890
1.51
25.17
5.1
4.1
7.40
7.40
ph
0.30
766
5592
1667
13679
1.45
23.01
10.0
7.6
1.22
1.22
mmol/l
0.34
1422
11989
2332
20508
1.48
21.58
8.7
7.9
79.42
81.85
u/l
1.77
2231
19495
2323
20461
1.47
20.91
5.2
4.4
10.38
11.03
mm/h
1.74
2189
19241
1451
11771
1.42
20.38
6.2
5.4
36.48
36.19
g/l
1.20
1362
11063
1505
12345
1.41
19.55
9.2
7.3
1.22
1.21
mmol/l
0.65
1392
11495
453
2917
1.64
19.36
2.6
2.3
372.52
376.75
nmol/l
0.15
423
2704
1893
16195
1.40
18.97
6.4
5.3
6.38
6.54
mmol/l
3.10
1780
15216
2479
22265
1.48
18.91
5.2
4.4
14.61
14.67
pmol/l
0.62
2300
20487
1021
7862
1.43
18.78
2.3
2.2
172.28
210.74
u/l
1.35
971
7450
1782
15152
1.39
18.14
4.9
3.8
3.15
4.51
estimate
0.16
387
3164
1782
15227
1.38
17.16
4.9
3.8
0.04
0.11
estimate
0.32
377
3005
1752
14994
1.36
16.35
4.9
3.8
0.00
0.00
estimate
0.34
384
3119
1464
12183
1.37
16.34
4.2
3.3
6.26
6.25
ph
0.12
796
6754
2777
25765
1.53
15.84
6.2
5.3
1.91
1.89
mu/l
0.29
2608
24119
1641
13974
1.35
15.44
6.7
6.7
12.06
12.08
umol/l
0.02
1566
13267
2080
18373
1.36
15.36
6.2
4.5
2814.06
1694.85
e6/l
0.24
33
220
147
718
2.09
15.31
5.3
5.8
1.21
1.27
mmol/l
0.34
133
620
1540
13015
1.35
15.10
3.2
2.6
76.06
75.30
nmol/l
0.49
1419
11965
1056
8430
1.37
14.95
3.0
2.7
56.82
68.63
u/l
0.66
989
7827
1735
14964
1.34
14.66
7.9
6.9
0.04
0.04
e9/l
0.19
1508
12807
1785
15460
1.34
14.66
8.2
7.2
0.19
0.19
e9/l
0.06
1570
13451
140
685
2.09
14.52
1.8
2.1
—
—
—
0
0
59
191
3.12
14.52
1.3
1.2
0.52
0.60
ratio
1.21
30
113
3046
29017
1.80
14.30
21.6
18.0
74.10
72.81
umol/l
1.17
3009
28681
1728
14942
1.33
14.11
7.9
6.9
0.56
0.57
e9/l
0.27
1502
12786
177
952
1.91
14.06
5.1
5.2
0.91
0.88
%
0.45
168
890
1017
8136
1.36
14.00
4.4
3.2
0.04
0.03
estimate
0.07
314
2475
662
4948
1.42
13.65
3.9
3.7
170.93
476.27
ng/l
4.64
460
3560
1363
11425
1.33
13.64
14.3
13.1
1.20
1.22
inr
0.72
1149
9502
2920
27561
1.58
13.61
20.4
16.8
3.96
3.95
mmol/l
0.32
2868
26937
2633
24345
1.43
13.60
6.0
5.7
37.95
38.46
mmol/mol
2.52
2481
22972
1682
14534
1.32
13.57
3.8
3.2
98.77
100.21
ug/l
0.12
1587
13699
316
2032
1.61
13.40
5.5
4.0
1.23
1.23
mmol/l
0.80
264
1748
1336
11196
1.33
13.28
4.8
3.6
0.03
0.03
estimate
0.05
328
2563
64
231
2.80
13.03
1.1
1.1
211.47
252.87
mg/l
1.14
53
200
1222
10131
1.33
13.02
8.0
7.1
—
—
—
0
0
2913
27527
1.56
12.96
20.3
16.6
139.70
139.66
mmol/l
0.48
2866
26970
185
1037
1.83
12.93
5.0
5.0
1.67
1.61
%
0.26
174
971
1601
13816
1.31
12.68
8.1
7.2
0.67
0.68
%
0.29
1519
13008
1754
15329
1.31
12.65
7.9
6.9
1.94
2.00
e9/l
1.31
1542
13481
154
820
1.92
12.63
1.7
1.9
395.86
526.92
mg/l
4.81
146
785
1601
13823
1.31
12.61
8.0
7.1
2.98
2.87
%
0.94
1518
13022
65
241
2.73
12.60
1.2
1.2
29.35
39.39
mg/l
1.61
49
197
1602
13863
1.30
12.27
8.2
7.2
8.77
8.67
%
0.73
1518
13068
142
744
1.95
12.22
1.8
2.1
1309.46
1049.50
e6/l
0.11
109
563
119
591
2.05
11.91
5.9
4.1
—
—
—
0
0
981
7959
1.33
11.88
1.5
1.5
2.18
2.08
u/ml
0.05
249
2041
2926
27765
1.54
11.78
17.9
14.6
21.81
23.05
mg/l
1.28
2431
22351
140
741
1.93
11.71
1.6
1.9
3.51
3.64
mmol/l
1.31
131
707
1033
8459
1.32
11.69
3.8
3.0
—
—
—
0
0
935
7553
1.33
11.62
2.4
2.5
2.72
2.71
mg/l
0.01
809
6598
200
1186
1.73
11.56
2.0
1.7
9.36
8.27
u/l
0.62
151
886
1641
14314
1.29
11.55
8.0
7.0
29.58
29.51
%
0.09
1569
13663
101
477
2.15
11.54
5.8
7.1
11.54
11.27
mmol/l
0.30
91
422
1877
16664
1.30
11.52
10.7
9.8
3.84
3.97
e9/l
1.81
1643
14386
910
7330
1.33
11.51
1.8
1.7
19.77
20.28
nmol/l
0.55
779
6288
101
478
2.15
11.49
5.8
7.1
104.91
105.10
mmol/l
0.13
91
423
3154
30565
2.11
11.37
26.7
22.0
6.63
6.74
e9/l
1.65
3090
29795
535
3970
1.41
11.29
10.2
6.9
1.09
1.11
mmol/l
0.57
496
3704
138
736
1.91
11.29
1.8
2.1
7.76
34.04
e6/l
1.41
100
523
1349
11507
1.29
11.13
2.1
2.0
97.95
96.14
pmol/l
0.75
702
6098
3152
30554
2.08
11.10
26.6
21.9
90.16
90.21
fl
0.23
3122
30266
3152
30555
2.07
11.08
26.6
21.9
30.07
30.08
pg
0.11
3122
30267
3152
30556
2.07
11.06
27.4
22.5
40.23
40.65
%
1.04
3120
30257
3152
30558
2.07
11.03
26.7
22.0
4.51
4.51
e12/l
0.27
3086
29792
821
6556
1.34
10.93
6.0
4.7
—
—
—
0
0
3152
30568
2.06
10.86
26.9
22.2
134.61
134.88
g/l
0.52
3123
30283
3150
30548
2.04
10.75
26.7
22.0
256.28
257.09
e9/l
0.30
3091
29873
1110
9271
1.30
10.63
3.7
3.4
2.35
2.36
mmol/l
2.39
1028
8486
2593
24172
1.36
10.62
22.0
17.9
13.46
13.46
%
0.11
2569
23857
523
3917
1.40
10.41
1.9
1.7
1199.98
1163.80
nmol/l
0.41
399
2989
684
5359
1.35
10.26
3.7
2.9
522.33
537.37
mosm/kgh2o
1.02
601
4693
548
4146
1.39
10.25
2.4
2.8
29.19
29.69
s
1.54
537
4048
1313
11243
1.28
10.24
2.1
1.9
1.31
1.35
mmol/l
0.70
1107
9633
57
221
2.60
10.19
2.1
3.0
2.06
1.76
umol/l
0.94
52
207
1600
14069
1.27
9.93
7.8
6.9
55.25
55.66
%
0.69
1548
13498
540
4099
1.38
9.88
1.4
1.4
464.90
506.80
titre
0.24
98
821
106
542
1.99
9.85
5.8
4.7
2.10
2.44
mmol/l
0.75
70
357
3002
28806
1.55
9.69
13.3
11.4
26.19
25.73
u/l
0.28
2929
28056
25
60
4.19
9.61
1.9
2.6
1.35
1.20
umol/l
0.59
20
48
811
6577
1.31
9.47
3.4
2.8
335.34
333.09
umol/l
0.23
702
5884
41
139
2.97
9.43
1.6
1.1
75.86
72.93
%
—
7
15
1100
9289
1.28
9.37
4.0
3.6
242.10
62.94
ng/l
0.42
663
6018
757
6092
1.31
9.33
2.1
2.1
0.99
1.24
mg/l
1.79
573
4619
226
1464
1.58
9.29
8.6
10.8
16.14
16.07
%
0.12
219
1411
767
6197
1.31
9.16
4.1
2.7
6.95
6.72
e6/l
0.13
695
5613
326
2297
1.46
9.04
5.9
3.8
—
—
—
0
0
226
1476
1.57
8.97
6.2
6.6
24.35
24.51
mmol/l
0.23
218
1409
651
5155
1.33
8.95
1.8
1.7
436.59
35520692.85
pmol/l
4.56
535
4344
184
1147
1.64
8.86
15.9
9.7
1.46
1.32
mg/l
1.43
169
1077
317
2240
1.46
8.66
2.5
2.3
12.02
12.18
nmol/l
0.11
286
2023
304
2133
1.47
8.61
5.8
4.5
77.96
78.20
ng/l
0.02
273
1894
273
1875
1.50
8.60
3.3
3.2
146.89
185.45
ng/l
1.49
252
1691
2667
25164
1.33
8.60
5.0
4.6
5.70
5.81
mmol/l
5.17
2461
23307
829
6819
1.29
8.56
4.4
3.7
1.02
1.70
kg/l
1.08
547
4467
1488
13118
1.25
8.52
2.9
2.8
—
—
estimate
—
0
0
1110
9481
1.26
8.37
4.0
3.4
32.66
33.26
u/l
0.07
1053
8968
271
1870
1.49
8.35
3.5
3.4
4.55
4.61
pmol/l
0.50
248
1672
580
4566
1.33
8.25
5.9
4.7
0.81
0.82
mmol/l
0.57
542
4338
996
8428
1.26
8.07
3.4
2.9
0.15
0.01
0.94
20
147
473
3628
1.35
8.00
1.3
1.2
—
—
—
0
0
321
2315
1.43
7.86
1.3
1.2
122.32
150.00
u/ml
0.71
126
827
548
4308
1.33
7.84
3.4
2.6
2.42
2.38
g/l
0.83
510
3987
389
2919
1.38
7.55
1.2
1.2
—
—
—
0
0
584
4660
1.31
7.49
3.4
2.6
13.07
13.52
umol/l
0.81
542
4356
2043
18782
1.23
7.44
3.8
3.4
41.92
43.05
u/l
0.27
1921
17816
126
746
1.71
7.42
3.4
3.0
55.97
56.80
%
0.30
126
746
262
1840
1.46
7.40
1.3
1.3
45.17
54.10
au/ml
—
10
113
329
2413
1.40
7.32
3.1
3.1
10.15
10.27
g/l
0.17
309
2241
644
5225
1.29
7.26
1.4
1.3
33.55
30.80
iu/ml
0.15
175
1520
840
7051
1.26
7.14
1.7
1.6
2.01
2.16
g/l
2.45
524
4251
20
52
3.86
6.96
2.8
2.5
5.20
5.00
ug/l
0.06
20
52
278
1999
1.43
6.92
2.4
2.4
18.84
20.25
au/ml
0.12
16
203
324
2393
1.39
6.92
7.7
8.9
120.80
122.12
g/l
0.57
318
2338
488
3845
1.32
6.82
2.0
2.0
—
—
—
0
0
257
1829
1.44
6.77
1.2
1.2
381.43
143.04
titre
—
7
68
954
8163
1.24
6.77
5.4
3.9
0.00
0.00
estimate
1.74
356
2934
233
1629
1.46
6.75
1.9
1.6
24.06
23.14
iu/l
0.15
181
1302
546
4381
1.29
6.66
2.3
2.7
97.33
113.20
ug/g
1.02
430
3517
499
3966
1.30
6.54
3.5
2.6
21.63
22.74
%
1.24
464
3696
822
6953
1.24
6.43
3.2
3.3
1014.13
1172.26
ng/l
0.87
693
5901
142
906
1.59
6.31
1.4
1.4
—
—
—
0
0
331
2491
1.36
6.30
4.6
4.7
0.92
0.91
%
0.03
106
724
321
2412
1.37
6.17
4.8
5.0
0.05
0.23
%
0.71
87
581
17
43
3.96
6.15
1.1
1.2
0.62
0.72
umol/24h
—
10
27
138
882
1.59
6.10
2.0
1.9
41.63
40.60
nmol/l
0.13
138
854
590
4838
1.27
6.01
1.3
1.3
5.46
9.65
u/ml
1.30
215
1848
2705
25856
1.27
5.95
5.2
4.8
4.63
4.64
mmol/l
0.09
2538
24406
315
2379
1.36
5.87
4.4
4.5
0.67
0.68
%
0.02
98
693
316
2394
1.35
5.77
4.7
4.8
0.12
0.12
%
0.02
89
626
376
2924
1.32
5.75
7.3
8.3
5.10
5.12
kpa
0.15
363
2817
376
2925
1.32
5.74
7.3
8.3
12.96
12.77
kpa
0.27
363
2820
2725
26107
1.27
5.63
5.8
5.3
2.72
2.72
mmol/l
0.02
2559
24528
259
1909
1.39
5.62
1.3
1.2
—
—
—
0
0
305
2308
1.35
5.62
1.4
1.3
247.03
257.33
u/ml
0.07
277
2151
408
3224
1.30
5.56
8.6
5.5
5.87
5.83
kpa
0.48
396
3133
824
7065
1.22
5.55
4.6
4.3
—
—
—
0
0
373
2916
1.31
5.50
7.4
8.3
7.41
7.41
ph
0.05
208
1544
370
2891
1.31
5.47
7.3
8.3
0.85
0.83
mmol/l
0.02
300
2359
129
834
1.57
5.46
1.1
1.1
3.95
8.87
eliau/ml
0.88
12
119
408
3233
1.30
5.44
8.6
5.6
7.37
7.37
ph
1.41
274
1905
240
1759
1.39
5.40
2.9
2.3
9839.66
7439.28
u/l
0.34
67
655
107
671
1.61
5.17
3.1
2.5
126.54
130.83
g/l
1.20
93
553
71
398
1.80
5.16
2.1
2.2
—
—
—
0
0
124
808
1.55
5.10
2.6
2.5
—
—
—
0
0
396
3153
1.29
5.09
8.8
5.5
1.73
1.57
mmol/l
0.47
340
2688
272
2062
1.35
4.97
3.9
2.4
0.23
0.46
e6/l
2.14
262
1960
2678
25695
1.24
4.90
5.1
4.7
1.48
1.47
mmol/l
0.63
2504
24109
1032
9145
1.19
4.76
5.0
3.4
59.97
71.94
e6/l
0.29
820
6877
1461
13330
1.17
4.73
14.3
11.2
0.01
0.00
e9/l
0.48
1210
10789
67
383
1.76
4.60
1.2
1.6
39.47
104.48
mu/l
1.39
59
352
64
363
1.78
4.52
3.3
2.6
1466.65
1339.14
e6/l
0.34
55
289
70
409
1.73
4.47
1.6
1.6
328.44
354.40
mu/l
0.45
62
322
329
2602
1.29
4.46
14.9
8.8
8.33
8.45
mmol/l
0.14
316
2513
414
3369
1.26
4.46
1.4
1.5
—
—
—
0
0
25
99
2.53
4.45
1.2
1.4
111.50
118.64
nmol/l
0.10
14
73
28
120
2.34
4.23
2.9
1.9
—
—
—
0
0
326
2600
1.28
4.15
7.8
8.7
95.94
95.64
%
0.32
315
2513
217
1636
1.35
4.15
8.4
4.6
126.95
129.50
g/l
1.04
211
1589
386
3144
1.26
4.13
4.1
3.2
1.58
1.73
%
2.60
346
2843
413
3393
1.25
4.10
1.9
1.7
—
—
—
0
0
348
2806
1.27
4.06
8.8
5.3
4.87
4.70
kpa
0.63
338
2726
52
287
1.82
4.05
3.3
2.8
256.93
211.61
e6/l
0.46
43
217
432
3576
1.24
4.00
2.4
3.2
4.36
4.61
e9/l
0.35
385
3144
261
2036
1.31
3.95
3.0
2.9
66.18
66.36
g/l
0.15
239
1884
123
849
1.46
3.93
1.3
1.4
301.47
298.21
ug/g
0.05
70
486
2536
24342
1.19
3.90
4.3
4.0
1.24
1.26
mmol/l
0.79
2363
22650
299
2379
1.28
3.89
3.6
3.1
65.36
69.94
e9/l
1.57
223
1680
104
696
1.51
3.87
2.3
2.2
11.34
11.75
mg/l
0.21
95
650
163
1188
1.39
3.87
2.0
1.7
—
—
—
0
0
31
145
2.15
3.85
1.1
1.1
0.66
4.13
nmol/l
—
6
27
1036
9313
1.16
3.85
4.1
3.5
7.38
7.82
mmol/l
2.23
894
8047
87
562
1.56
3.80
1.6
1.5
0.28
0.38
nmol/l
0.96
74
426
33
160
2.07
3.75
1.5
1.7
1.56
4.05
nmol/l
1.04
28
132
151
1093
1.40
3.74
1.3
1.2
0.28
0.78
u/ml
—
9
71
89
584
1.54
3.65
3.0
3.1
8.59
8.48
umol/l
0.02
74
453
20
79
2.54
3.62
2.5
2.6
0.62
0.61
mmol/l
0.21
20
79
289
2315
1.27
3.58
9.5
5.7
7.41
7.41
ph
0.78
256
1899
460
3884
1.21
3.52
1.8
1.6
—
—
—
0
0
1178
10755
1.15
3.46
5.9
4.0
63.73
89.39
e6/l
0.87
854
7292
64
394
1.64
3.44
2.1
2.8
—
—
—
0
0
242
1907
1.29
3.42
2.0
1.9
1.29
1.28
g/l
0.03
222
1776
892
7999
1.16
3.35
4.6
3.3
0.33
0.38
e6/l
0.47
677
5799
59
359
1.65
3.33
1.4
1.4
364.28
381.57
pmol/l
0.12
50
314
860
7695
1.16
3.32
4.6
3.2
11.33
122.12
estimate
—
6
21
10
23
4.35
3.30
1.2
1.2
—
—
—
0
0
291
2359
1.26
3.28
9.5
5.7
5.02
5.11
kpa
1.24
285
2280
2527
24351
1.17
3.25
22.2
18.3
333.27
332.78
g/l
1.98
2518
24207
580
5040
1.18
3.24
3.1
2.8
2.44
2.45
mmol/l
0.75
522
4518
799
7124
1.16
3.23
5.1
4.7
90.11
90.46
%
0.15
790
6980
98
678
1.46
3.16
1.2
1.2
45.50
46.61
u/ml
—
7
60
118
846
1.41
3.14
2.3
2.0
3.52
10.27
iu/l
0.51
53
350
133
976
1.38
3.09
1.3
1.3
—
—
—
0
0
181
1394
1.31
3.06
1.9
1.6
285.12
310.99
mu/l
0.72
162
1266
881
7939
1.15
3.05
3.6
3.5
67.52
51.86
mg/l
0.80
539
5111
641
5648
1.17
3.01
1.9
1.7
—
—
—
0
0
55
340
1.63
2.96
2.0
2.1
0.84
0.89
%
0.27
37
216
48
287
1.68
2.93
3.5
2.8
561.08
548.37
e6/l
0.05
37
208
273
2232
1.24
2.88
9.4
6.0
23.82
23.94
mmol/l
0.32
268
2216
390
3307
1.20
2.87
3.4
3.5
5.34
7.13
umol/l
3.66
324
2878
18
77
2.34
2.81
1.0
1.1
—
—
—
0
0
25
123
2.04
2.80
1.1
1.1
106.43
260.76
ng/l
—
7
30
10
28
3.58
2.78
1.1
1.2
1.48
1.87
umol/24h
—
10
28
140
1057
1.34
2.75
6.1
4.6
343.37
363.02
mg/l
0.10
75
538
5
6
8.33
2.75
4.8
10.2
—
—
—
0
0
32
175
1.83
2.67
1.1
1.1
1434.72
1510.09
miu/ml
0.14
32
175
50
311
1.62
2.66
3.9
4.0
6.26
6.99
mmol/l
1.75
40
264
156
1203
1.31
2.66
2.8
3.5
21.73
21.39
s
0.31
134
1086
62
406
1.54
2.65
3.9
3.6
1.39
1.46
%
0.06
56
371
1143
10557
1.13
2.64
3.3
2.9
—
—
—
0
0
36
205
1.76
2.64
4.2
3.0
0.32
0.30
e9/l
0.06
24
112
887
8070
1.13
2.62
4.2
4.2
12.74
10.72
mg/mmol
0.29
531
5072
157
1216
1.30
2.60
2.1
1.8
6.42
6.90
iu/ml
0.09
29
283
79
547
1.45
2.60
4.2
3.3
1.60
1.51
mmol/l
0.25
73
527
68
457
1.50
2.59
1.4
1.7
—
—
—
0
0
68
457
1.50
2.59
1.4
1.7
—
—
—
0
0
68
458
1.49
2.57
1.4
1.7
—
—
—
0
0
68
458
1.49
2.57
1.4
1.7
—
—
—
0
0
46
283
1.63
2.56
1.7
1.6
48.32
58.86
%
0.84
25
182
64
426
1.51
2.56
1.5
1.4
16.61
22.11
u/l
1.11
59
355
328
2771
1.20
2.53
2.8
2.8
0.22
0.21
g/l
0.19
310
2599
774
6995
1.14
2.52
2.3
2.1
—
—
—
0
0
96
694
1.39
2.50
1.0
1.1
—
—
—
0
0
102
745
1.38
2.50
2.4
1.6
—
—
—
0
0
689
6187
1.14
2.47
5.9
5.2
2.65
2.41
ug/l
0.18
632
5599
55
357
1.55
2.47
2.5
1.7
282.55
282.83
mosm/kgh2o
0.03
40
269
124
939
1.33
2.43
2.0
1.8
1.14
1.19
g/l
1.13
111
896
27
145
1.87
2.40
1.2
1.3
—
—
—
0
0
18
83
2.17
2.40
2.8
2.2
20.34
16.94
umol/l
0.39
18
83
15
65
2.31
2.30
1.2
1.3
—
—
—
0
0
106
793
1.35
2.27
4.2
2.4
—
—
—
0
0
12
47
2.56
2.26
1.3
3.0
—
—
—
0
0
782
7121
1.13
2.24
4.5
3.7
0.17
0.14
—
6
59
41
256
1.61
2.20
1.1
1.1
—
—
—
0
0
119
911
1.32
2.19
2.1
1.8
0.23
0.23
g/l
0.10
106
865
59
402
1.47
2.16
6.3
5.4
430.81
369.67
umol/l
1.99
52
360
29
167
1.74
2.10
3.7
4.3
1.83
1.54
ug/l
0.28
29
160
109
830
1.32
2.10
1.3
1.2
4.12
7.45
u/ml
—
6
74
95
709
1.35
2.09
2.5
1.6
138.96
130.37
au/ml
0.23
26
212
316
2714
1.18
2.06
2.6
2.4
35.09
56.16
u/l
0.61
266
2272
174
1410
1.25
2.06
8.6
4.4
1.15
1.24
%
0.62
174
1400
105
800
1.32
2.02
1.3
1.4
60.91
84.94
titre
1.51
11
83
20
104
1.93
1.99
2.4
2.1
32.90
30.49
%
0.32
20
104
27
155
1.75
1.99
5.1
2.9
291.75
186.63
umol/l
0.39
16
92
27
156
1.74
1.95
1.3
1.3
128.85
131.79
nmol/l
0.15
27
156
330
2862
1.17
1.93
10.5
9.5
—
—
—
0
0
9
33
2.73
1.92
1.4
2.5
1.50
1.89
mg/l
—
9
27
13
58
2.24
1.90
1.3
1.2
—
—
—
0
0
171
1398
1.23
1.89
8.6
4.3
0.61
0.62
%
0.22
171
1391
39
251
1.56
1.88
1.3
1.2
100.38
111.45
pmol/l
0.80
39
251
259
3017
0.85
1.86
4.5
4.6
33.35
32.53
%
0.49
176
2067
113
882
1.29
1.85
1.3
1.2
24.87
37.24
u/ml
—
7
46
55
383
1.44
1.84
2.5
2.5
27.27
35.75
iu/ml
—
6
35
33
206
1.61
1.82
1.6
1.5
35.71
34.39
%
0.06
17
129
156
1272
1.24
1.79
2.3
2.3
—
—
—
0
0
73
539
1.36
1.77
1.4
1.6
0.62
0.77
g/l
0.95
58
431
38
248
1.54
1.75
1.2
1.1
—
—
—
0
0
119
943
1.27
1.75
1.9
2.4
400.40
361.00
ug/l
0.12
109
895
49
338
1.46
1.74
1.3
1.3
0.16
0.23
nmol/l
0.70
41
264
106
830
1.29
1.72
1.3
1.3
2.46
8.44
u/ml
—
8
120
137
1111
1.24
1.67
1.5
1.8
1.47
1.48
g/l
0.04
115
968
960
8979
1.10
1.62
6.1
6.5
—
—
—
0
0
29
181
1.61
1.62
1.4
1.4
191.69
216.32
pmol/l
0.19
29
181
26
158
1.65
1.61
2.2
2.3
123.96
156.41
e6/l
0.38
26
153
107
848
1.27
1.59
2.1
1.5
242.73
230.20
u/ml
0.18
63
469
158
1309
1.22
1.58
1.5
1.5
—
—
—
0
0
15
77
1.95
1.58
1.7
1.2
21.74
7.29
pmol/l
—
5
32
14
261
0.53
1.57
3.4
2.7
—
—
—
0
0
27
167
1.62
1.57
2.6
2.7
43.89
42.65
%
0.16
18
84
18
99
1.82
1.56
1.2
1.2
—
—
—
0
0
69
517
1.34
1.55
3.7
4.1
—
—
—
0
0
19
107
1.78
1.54
4.1
4.0
—
—
—
0
0
77
588
1.32
1.53
1.6
1.5
3.56
4.57
ug/l
0.91
70
542
90
1140
0.78
1.51
1.1
1.1
1.60
1.54
g/l
1.38
90
1140
6
21
2.86
1.50
1.3
1.2
—
—
—
0
0
64
477
1.35
1.50
1.1
1.1
1.33
3.92
eliau/ml
2.27
23
202
207
1770
1.18
1.49
10.4
5.8
—
—
—
0
0
9
39
2.31
1.42
1.6
1.3
—
—
—
0
0
19
110
1.73
1.42
1.2
1.4
7.39
7.39
ph
0.02
14
76
29
188
1.55
1.42
1.4
1.2
—
—
—
0
0
287
3240
0.87
1.41
1.9
1.9
3.38
3.42
ratio
0.19
209
2443
185
1576
1.18
1.41
1.3
1.2
—
—
—
0
0
29
189
1.54
1.39
1.3
1.1
—
—
—
0
0
83
651
1.28
1.38
13.3
5.7
66.37
63.13
%
0.80
83
646
48
348
1.38
1.36
1.5
1.4
2.85
2.66
g/l
0.34
39
267
48
348
1.38
1.36
1.5
1.4
7.37
6.46
g/l
1.44
37
266
48
348
1.38
1.36
1.5
1.4
0.44
0.37
g/l
0.52
39
263
5
17
2.94
1.35
1.2
1.0
—
—
—
0
0
34
231
1.48
1.35
1.2
1.5
—
—
—
0
0
44
315
1.40
1.34
2.5
3.0
—
—
—
0
0
10
47
2.13
1.33
1.1
1.2
—
—
—
0
0
155
1309
1.19
1.32
1.7
1.7
0.26
0.31
mg/l
0.60
70
604
46
334
1.38
1.30
2.5
2.3
—
—
—
0
0
8
34
2.35
1.29
1.3
1.1
—
—
—
0
0
6
134
0.45
1.27
1.0
1.1
—
—
—
0
0
38
268
1.42
1.27
1.2
1.1
—
—
—
0
0
30
202
1.49
1.26
1.0
1.0
—
—
—
0
0
140
1178
1.20
1.25
1.1
1.1
—
—
—
0
0
32
219
1.46
1.25
1.1
1.1
—
—
—
0
0
64
493
1.30
1.24
1.1
1.1
—
—
—
0
0
5
119
0.42
1.24
1.0
1.7
—
—
—
0
0
47
346
1.36
1.23
1.6
1.4
—
—
—
0
0
11
56
1.97
1.21
1.5
1.2
—
—
—
0
0
467
4286
1.10
1.18
2.0
1.9
—
—
—
0
0
60
462
1.30
1.18
1.3
1.3
2.21
4.37
u/ml
2.04
28
217
45
332
1.36
1.18
2.1
3.4
—
—
—
0
0
54
410
1.32
1.17
1.2
1.2
—
—
—
0
0
81
649
1.25
1.17
3.2
3.2
32.57
35.93
umol/l
0.65
76
598
1109
10562
1.07
1.17
2.1
2.1
—
—
—
0
0
0
36
0.00
1.14
0.0
1.1
—
3.66
—
0
23
27
183
1.48
1.12
3.8
4.0
0.52
0.76
index
1.25
27
183
70
555
1.27
1.12
1.2
1.2
—
—
—
0
0
148
1267
1.17
1.11
1.1
1.1
—
—
—
0
0
254
2262
1.13
1.11
1.4
1.5
—
—
—
0
0
7
31
2.26
1.10
1.6
2.7
101.71
99.68
g/l
—
7
31
88
1070
0.82
1.10
1.1
1.1
0.57
0.63
ratio
0.49
12
120
17
104
1.64
1.09
3.2
1.8
—
—
—
0
0
31
218
1.42
1.08
1.5
1.6
—
—
—
0
0
7
32
2.19
1.08
9.4
2.2
—
—
—
0
0
277
2487
1.12
1.07
1.6
1.5
—
—
—
0
0
539
5011
1.09
1.05
3.9
3.0
0.85
1.13
e6/l
1.23
302
2611
99
823
1.21
1.04
2.3
2.4
9.30
10.20
g/l
1.90
88
745
220
1953
1.13
1.03
2.3
2.3
6.45
7.62
ug/l
0.29
195
1734
7
34
2.06
1.02
1.9
1.2
6.16
5.75
mmol/l
—
7
34
177
1549
1.15
1.02
1.8
1.4
—
—
—
0
0
65
518
1.26
1.02
2.1
1.8
66.75
63.64
mmol/l
0.24
53
421
20
131
1.53
0.99
1.0
1.1
—
—
—
0
0
150
1301
1.16
0.98
2.3
2.4
—
—
—
0
0
26
181
1.44
0.97
1.3
1.4
143.69
78.20
umol/l
0.54
26
181
44
570
0.77
0.97
1.2
1.1
24.71
1022.22
iu/ml
—
7
143
330
3012
1.11
0.96
1.4
1.4
—
—
—
0
0
27
376
0.71
0.96
1.9
1.7
—
—
—
0
0
12
69
1.74
0.96
1.4
1.3
—
—
—
0
0
59
469
1.26
0.95
1.9
2.0
—
—
—
0
0
86
713
1.21
0.95
1.2
1.1
32.02
20.67
au/ml
0.41
20
148
0
32
0.00
0.95
0.0
1.1
—
0.03
—
0
32
7
37
1.89
0.94
1.3
1.0
—
—
—
0
0
37
278
1.33
0.91
3.8
3.7
14.78
13.89
index
0.19
27
183
947
9042
1.07
0.91
1.6
1.6
—
—
—
0
0
19
126
1.51
0.90
1.1
1.2
766.67
1060.87
titre
—
6
23
23
159
1.45
0.90
1.9
2.7
1769.35
1028.12
u/ml
0.34
23
159
81
672
1.21
0.90
3.6
3.5
1.59
3.54
ratio
1.45
37
377
39
296
1.32
0.90
2.8
2.1
19.18
24.47
mg/l
0.37
15
110
6
29
2.07
0.89
1.7
10.9
0.13
0.19
%
—
6
29
41
316
1.30
0.86
1.3
1.3
—
—
nmol/l
—
0
0
11
64
1.72
0.85
1.5
1.2
—
—
—
0
0
11
64
1.72
0.85
1.5
1.2
—
—
—
0
0
11
64
1.72
0.85
1.5
1.2
—
—
—
0
0
146
1281
1.15
0.85
2.2
1.9
—
—
—
0
0
22
153
1.44
0.85
1.1
1.0
—
—
—
0
0
49
390
1.26
0.81
1.3
1.2
—
—
—
0
0
16
105
1.52
0.81
1.1
1.3
—
—
—
0
0
53
653
0.81
0.81
2.4
2.0
0.86
0.79
nmol/l
0.32
47
554
15
97
1.55
0.81
1.5
1.3
—
—
—
0
0
40
312
1.28
0.78
3.1
4.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
0.11
—
0
13
7
125
0.56
0.77
2.7
2.8
—
—
—
0
0
16
107
1.50
0.75
1.0
1.0
32.79
34.22
iu/ml
0.02
16
107
10
59
1.70
0.75
1.3
1.4
2.49
3.26
mmol/l
—
10
52
20
141
1.42
0.74
1.2
1.2
8.45
9.67
mm/h
0.30
20
141
133
1175
1.14
0.73
1.2
1.2
—
—
—
0
0
223
2440
0.91
0.73
1.7
1.6
3.46
3.40
mmol/l
0.35
139
1648
167
1497
1.12
0.73
3.2
1.9
—
—
—
0
0
9
56
1.61
0.72
2.6
1.5
0.92
1.19
iu/ml
—
9
26
20
142
1.41
0.72
1.5
6.7
73.07
73.75
mg/l
0.01
14
114
10
60
1.67
0.71
2.0
4.1
85.80
27.34
mg/l
—
5
21
45
362
1.25
0.71
1.5
1.4
6.64
7.12
mmol/l
0.70
39
323
14
93
1.51
0.69
1.2
1.3
29.79
27.91
s
0.58
14
93
19
135
1.41
0.68
1.1
1.1
—
—
—
0
0
12
77
1.56
0.68
3.6
8.5
1.20
1.20
mmol/l
0.04
12
72
224
2434
0.91
0.65
4.0
4.3
3.04
18.36
ug/l
3.56
176
1934
23
172
1.34
0.63
2.0
2.6
647.33
612.25
ml
0.13
12
118
42
343
1.23
0.60
1.1
1.1
5.50
8.31
iu/ml
—
9
82
21
156
1.35
0.60
1.3
1.5
5.16
7.22
u/l
1.12
16
137
0
20
0.00
0.60
0.0
1.1
—
1.59
—
0
9
397
3742
1.07
0.60
3.3
3.2
0.72
0.75
ug/l
0.41
251
2352
41
335
1.23
0.59
1.5
1.2
—
—
—
0
0
10
64
1.56
0.58
8.6
5.2
8.80
8.30
%
—
10
64
10
64
1.56
0.58
4.3
2.6
46.30
44.47
%
—
10
64
17
123
1.38
0.57
1.2
1.7
—
—
—
0
0
6
36
1.67
0.56
2.0
1.3
100.50
162.84
mmol/l
—
6
30
11
73
1.51
0.56
3.7
6.9
5.20
5.05
kpa
0.29
11
73
20
150
1.33
0.55
1.1
1.2
—
—
—
0
0
16
217
0.74
0.55
1.1
1.1
—
—
—
0
0
50
421
1.19
0.55
1.9
1.8
—
—
—
0
0
489
4655
1.06
0.55
4.2
3.1
4.38
2.87
e6/l
1.04
248
2250
6
39
1.54
0.53
4.3
7.0
38.97
34.24
ug/min
—
6
32
940
9106
1.04
0.52
2.7
2.5
—
—
—
0
0
17
226
0.75
0.52
2.8
2.0
—
—
—
0
0
6
40
1.50
0.51
1.0
1.1
—
—
—
0
0
6
40
1.50
0.51
2.2
2.3
—
—
—
0
0
38
314
1.21
0.51
1.1
1.1
19.12
17.61
u/ml
0.09
12
105
253
2699
0.93
0.51
2.4
2.1
0.08
0.01
estimate
0.54
51
596
12
168
0.71
0.50
1.3
1.4
168.10
16.22
u/ml
—
6
126
138
1257
1.10
0.50
1.4
1.3
260.42
226.44
miu/ml
0.44
58
611
6
41
1.46
0.50
1.2
1.3
—
24.80
—
0
5
6
41
1.46
0.50
1.5
2.6
6.77
7.88
mmol/l
—
6
20
58
500
1.16
0.50
1.1
1.1
—
—
—
0
0
85
755
1.13
0.48
4.6
3.7
26.40
44.78
mg/l
3.06
61
650
7
111
0.63
0.48
2.7
2.9
—
—
—
0
0
85
756
1.13
0.48
4.6
3.7
60.87
60.25
mg/l
0.01
62
649
190
1762
1.08
0.47
2.9
1.9
—
—
—
0
0
172
1590
1.09
0.46
10.5
6.1
24.12
24.49
mmol/l
1.38
167
1530
5
84
0.59
0.45
1.0
1.0
184.00
164.29
g/l
—
5
84
11
77
1.43
0.45
1.2
1.0
—
—
—
0
0
11
77
1.43
0.45
1.2
1.0
—
—
—
0
0
11
77
1.43
0.45
1.2
1.0
—
—
—
0
0
35
292
1.20
0.44
3.3
4.7
88.18
81.73
u/ml
0.05
16
90
50
434
1.15
0.41
2.9
3.5
10.66
71.62
u/ml
0.93
50
426
202
1891
1.07
0.41
2.9
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
3.0
—
0.57
—
0
15
0
17
0.00
0.40
0.0
1.1
—
0.07
—
0
8
222
2088
1.07
0.40
1.5
1.6
1170.50
971.55
mu/l
0.98
199
1833
44
507
0.87
0.40
2.7
2.5
110.00
108.60
ug/min
0.01
20
308
203
1904
1.07
0.40
3.0
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
0.14
—
0
13
60
530
1.13
0.40
1.3
1.2
—
—
—
0
0
106
968
1.10
0.40
2.2
2.0
5.73
1.84
ug/l
0.87
90
863
20
159
1.26
0.39
4.7
7.1
3.95
129.28
ug/l
0.63
13
103
5
35
1.43
0.39
2.8
2.3
—
4.62
—
0
17
5
35
1.43
0.39
1.0
1.3
177.82
109.92
ng/l
—
5
21
0
19
0.00
0.39
0.0
1.1
—
0.13
—
0
10
202
1898
1.07
0.38
2.8
1.8
—
—
—
0
0
28
233
1.20
0.38
1.5
1.4
45322.31
111244.34
e6/l
0.89
13
131
76
840
0.90
0.37
1.6
1.6
—
—
—
0
0
9
122
0.74
0.35
1.6
1.4
190.33
159.35
mmol/24h
—
9
122
16
126
1.27
0.35
2.5
3.1
—
87.32
—
0
19
38
329
1.16
0.34
1.2
1.2
—
—
—
0
0
74
670
1.11
0.34
1.2
1.1
—
—
—
0
0
6
44
1.36
0.34
1.3
1.3
16.67
22.41
%
—
6
34
6
45
1.33
0.33
1.3
1.4
—
—
—
0
0
23
275
0.83
0.33
1.2
1.2
—
—
—
0
0
29
246
1.18
0.33
1.1
1.3
—
—
—
0
0
74
672
1.10
0.33
1.2
1.1
—
—
—
0
0
115
1067
1.08
0.32
1.7
1.6
9.28
12.59
u/ml
0.41
28
245
13
101
1.29
0.31
3.2
3.3
—
—
—
0
0
7
98
0.71
0.30
1.0
1.2
—
0.13
—
0
11
78
714
1.09
0.30
1.1
1.1
10.16
5.42
u/ml
0.56
48
412
21
250
0.84
0.30
1.8
2.5
24.44
28.97
mg/l
0.19
16
168
26
302
0.86
0.29
2.7
2.2
—
—
—
0
0
51
459
1.11
0.28
1.3
1.2
—
—
—
0
0
29
252
1.15
0.27
3.8
3.4
55.21
56.58
%
0.12
24
224
72
663
1.09
0.26
1.6
1.7
10470.85
13234.42
e6/l
0.29
48
469
19
160
1.19
0.25
2.6
1.9
97.78
102.03
ng/l
0.07
19
160
27
235
1.15
0.25
1.4
1.4
—
—
—
0
0
11
137
0.80
0.24
2.9
2.4
14.53
16.36
%
1.39
11
137
197
1886
1.05
0.23
3.0
1.8
—
—
—
0
0
87
813
1.07
0.23
1.2
1.2
—
—
—
0
0
15
125
1.20
0.22
2.5
2.5
2.54
1.98
mmol/l
—
9
97
130
1366
0.95
0.22
2.8
2.1
0.03
0.00
estimate
0.44
39
465
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.06
—
0
10
0
11
0.00
0.21
0.0
1.5
—
2.00
—
0
5
106
1119
0.94
0.21
1.5
1.5
79.02
60.44
ug/l
0.76
92
969
30
267
1.12
0.21
1.1
1.4
7.05
4.34
u/ml
0.26
19
155
6
48
1.25
0.20
1.2
1.2
61.33
69.10
ug/l
—
6
48
31
278
1.12
0.20
1.5
1.4
7798.88
2351.85
e6/l
0.40
16
191
73
684
1.07
0.19
1.4
1.3
—
—
—
0
0
51
471
1.08
0.19
1.2
1.7
—
—
—
0
0
76
807
0.94
0.19
1.6
1.5
1.27
1.27
mm
0.02
56
592
71
666
1.07
0.18
1.1
1.1
11.14
8.77
u/ml
0.15
40
357
125
1304
0.96
0.17
3.6
3.2
1.02
1.02
ratio
0.12
108
1173
74
783
0.94
0.17
9.1
9.4
—
—
—
0
0
16
138
1.16
0.17
2.1
2.5
499.82
500.54
min
0.01
11
99
153
1471
1.04
0.17
3.6
3.3
56.43
63.73
u/ml
0.10
147
1422
24
214
1.12
0.17
1.2
1.1
—
—
—
0
0
7
63
1.11
0.17
1.7
1.3
—
—
—
0
0
143
1485
0.96
0.17
1.6
1.7
—
—
—
0
0
96
915
1.05
0.16
1.1
1.2
—
—
—
0
0
79
831
0.95
0.16
1.6
1.5
—
—
—
0
0
6
77
0.78
0.15
2.3
1.2
—
—
—
0
0
357
3491
1.02
0.15
1.3
1.3
—
—
—
0
0
30
276
1.09
0.13
1.1
1.2
0.42
2.73
u/ml
1.03
11
123
94
904
1.04
0.12
3.3
3.6
495.21
1733.46
u/ml
0.56
82
787
56
532
1.05
0.11
3.8
3.3
25.13
25.07
mg/l
0.00
41
354
277
2715
1.02
0.11
1.3
1.3
—
—
—
0
0
29
269
1.08
0.11
1.4
1.5
7.59
8.07
mmol/l
0.45
29
261
698
7046
0.99
0.11
2.7
2.4
—
—
—
0
0
97
936
1.04
0.11
1.2
1.2
2.73
6.26
u/ml
2.56
64
594
18
198
0.91
0.11
1.7
1.6
0.53
0.50
e9/l
0.12
18
198
10
86
1.16
0.10
3.2
1.5
—
—
—
0
0
87
901
0.96
0.10
1.1
1.2
3.84
2.56
u/ml
0.52
58
558
13
146
0.89
0.10
1.3
1.1
187.40
208.39
iu/ml
0.13
13
146
5
44
1.14
0.10
1.2
1.0
—
—
—
0
0
62
645
0.96
0.09
1.3
1.5
98.98
189.95
pmol/l
1.69
57
630
15
135
1.11
0.09
1.2
2.7
30.39
252.10
ug/l
0.64
15
121
10
87
1.15
0.09
1.0
1.3
104.40
69.17
ug/l
—
10
87
6
57
1.05
0.08
1.7
2.3
—
—
—
0
0
219
2225
0.98
0.08
2.6
2.5
6.08
6.14
ph
0.40
151
1473
5
64
0.78
0.08
1.2
2.7
2.24
3.25
nmol/l
—
5
58
18
195
0.92
0.08
2.0
2.3
—
—
—
0
0
7
68
1.03
0.07
1.0
1.1
—
—
—
0
0
31
327
0.95
0.07
1.5
1.4
—
—
—
0
0
6
70
0.86
0.07
1.5
1.4
49.48
51.72
%
—
6
62
43
411
1.05
0.07
3.1
3.4
0.81
0.82
nmol/l
0.06
34
341
8
76
1.05
0.07
2.3
1.9
—
—
—
0
0
7
80
0.87
0.07
1.0
1.5
11.14
7.61
mmol/l
—
7
80
27
285
0.95
0.07
1.1
1.1
—
—
—
0
0
8
91
0.88
0.06
3.3
2.8
—
—
—
0
0
128
1304
0.98
0.06
1.7
1.9
—
—
—
0
0
84
818
1.03
0.06
1.3
1.2
—
—
—
0
0
9
104
0.86
0.06
3.6
1.8
0.00
0.03
estimate
—
9
104
13
119
1.09
0.05
1.0
1.1
—
—
—
0
0
27
257
1.05
0.05
1.4
1.2
—
—
—
0
0
19
201
0.94
0.04
1.2
1.3
122.61
23.57
u/ml
0.36
11
147
21
221
0.95
0.04
1.1
1.2
—
—
—
0
0
93
913
1.02
0.04
1.2
1.2
0.41
1.09
u/ml
2.39
55
506
63
616
1.02
0.03
1.1
1.1
0.11
0.31
u/ml
1.08
32
249
13
139
0.93
0.03
2.2
2.2
6.25
8.34
mmol/l
3.83
13
139
30
310
0.97
0.03
1.8
2.4
18.84
22.94
ug/l
0.62
30
304
104
1053
0.99
0.03
1.3
1.2
1.16
2.63
u/ml
2.16
64
645
11
102
1.08
0.03
1.3
1.5
62.55
85.40
nmol/24h
0.64
11
102
19
198
0.96
0.02
1.5
1.1
—
38.70
—
0
16
18
172
1.05
0.02
1.1
1.0
—
—
—
0
0
18
172
1.05
0.02
1.1
1.0
-1.94
-2.83
mmol/l
—
5
50
10
107
0.93
0.02
1.4
1.7
—
—
—
0
0
27
263
1.03
0.01
1.1
1.2
—
196.25
—
0
8
27
263
1.03
0.01
1.1
1.2
295.00
184.69
titre
—
6
49
10
94
1.06
0.00
1.1
1.8
—
—
—
0
0
77
763
1.01
0.00
3.2
3.2
3.10
3.01
index
0.04
39
418
233
2333
1.00
0.00
4.3
4.0
7.36
7.35
ph
0.58
159
1700
23
230
1.00
0.00
1.5
1.5
—
—
—
0
0
11
108
1.02
0.00
1.3
1.1
—
—
—
0
0
24
242
0.99
0.00
1.5
1.4
14658.94
76163.51
e6/l
1.22
17
163
10
98
1.02
0.00
2.6
2.3
—
190.40
—
0
13
17
170
1.00
0.00
1.2
1.0
328.08
304.96
ng/l
0.10
12
112
28
276
1.01
0.00
1.4
1.2
—
—
—
0
0
19
185
1.03
0.00
1.1
1.0
20.14
19.52
mmol/l
0.40
19
175
32
318
1.01
0.00
1.2
1.4
1.60
11.39
u/ml
0.85
13
145
15
148
1.01
0.00
1.6
1.3
195.60
312.51
u/l
0.63
15
136
11
110
1.00
0.00
1.0
1.0
—
—
—
0
0
33
326
1.01
0.00
1.3
1.4
8.86
3.12
u/ml
0.37
13
174
17
169
1.00
0.00
1.2
1.0
832.08
740.72
ng/l
0.29
12
109
29
293
0.99
0.00
2.8
2.3
1.09
1.52
g/24h
0.67
19
174
19
194
0.98
0.00
2.6
2.2
1.30
3.83
u/ml
—
10
69
0
7
0.00
-0.00
0.0
1.6
—
423.57
—
0
7
5
59
0.85
-0.00
2.8
4.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.03
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
3085.71
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
62
0.97
-0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
98
0.92
-0.00
1.1
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_HYPERMETRO and mortality.

Females

Parameter HR [95% CI] p-value
H7_HYPERMETRO 1.047 [0.92, 1.2] 0.5
Birth year 0.994 [0.99, 1.0] 0.16

During the follow-up period (1.1.1998 — 31.12.2019), 1035 out of 19706 females with H7_HYPERMETRO died.

Males

Parameter HR [95% CI] p-value
H7_HYPERMETRO 1.28 [1.1, 1.49] 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 874 out of 16671 males with H7_HYPERMETRO died.

Mortality risk

Mortality risk for people of age

years, who have H7_HYPERMETRO.

N-year risk Females Males
1 0.108% 0.214%
5 0.595% 1.629%
10 1.473% 3.821%
15 2.768% 7.326%
20 4.922% 12.191%

Relationships between endpoints

Index endpoint: H7_HYPERMETRO – Hypermetropia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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