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Degeneration of the brain due to alcohol

EFO MESH Endpoint Browser PheWeb

G6_ALCODEGEN

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G31.2
  • Cause of death: ICD-10 — G31.2

2 out of 7 registries used, show all original rules.

896

4. Check minimum number of events

None

896

5. Include endpoints

None

896

6. Filter based on genotype QC (FinnGen only)

815

Control definitions (FinnGen only)

Control exclude
G6_NEURODEG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G31
Name in latin
Degeneratio systematis nervosi ex alcohol (aethylico)

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12921 2765 9998
Only index persons 10336 2353 7983
Unadjusted period prevalence (%)
Whole population 0.24 0.08 0.28
Only index persons 0.26 0.09 0.30
Median age at first event (years)
Whole population 58.75 58.87 58.62
Only index persons 58.94 59.19 58.87

-FinnGen-

Key figures

All Female Male
Number of individuals 815 137 678
Unadjusted period prevalence (%) 0.27 0.05 0.31
Median age at first event (years) 60.18 58.30 60.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
838
Matched controls
8380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
27.0
307.7
486
407
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
+∞
307.7
838
5
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
22.8
283.0
225
133
F10.25
ICD-10 Finland
Alcohol dependence continuous use
28.2
255.0
181
81
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
42.9
228.9
140
39
F10.20
ICD-10 Finland
Alcohol dependence currently independent
23.4
227.3
174
93
P15
ICPC
Chronic alcohol abuse
15.8
209.5
199
162
R56.8
ICD-10 Finland
Other and unspecified convulsions
12.0
170.7
193
204
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
22.9
170.5
129
66
N07BB01
ATC
disulfiram; oral
11.5
165.0
192
211
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
19.1
153.2
126
77
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
30.9
151.0
101
37
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
23.3
147.5
110
54
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
44.6
146.7
88
22
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
31.2
145.7
97
35
F10.24
ICD-10 Finland
Alcohol depence active use
19.9
144.7
116
67
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
18.3
143.1
120
76
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
64.2
137.0
76
13
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
23.8
134.3
99
47
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
23.3
121.6
90
43
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
18.6
116.7
96
58
N05BA02
ATC
chlordiazepoxide; systemic
12.6
116.3
121
111
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
4.9
115.3
474
1757
N05AH04
ATC
quetiapine; oral
5.2
104.3
282
740
K70.1
ICD-10 Finland
Alcoholic hepatitis
33.0
103.1
67
22
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
18.1
95.5
79
48
F10.09
ICD-10 Finland
Alcohol intoxication UNS
11.6
92.1
100
97
P16
ICPC
Acute alcohol abuse
14.0
90.1
86
68
K70.4
ICD-10 Finland
Alcoholic hepatic failure
30.7
78.4
52
18
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
7.7
77.0
117
174
K92.0
ICD-10 Finland
Haematemesis
9.7
75.2
92
105
AA1AD
NOMESCO Finland
CT of head and brain
3.6
74.5
425
1844
F05.9
ICD-10 Finland
Delirium, unspecified
11.2
74.1
81
79
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.8
72.1
311
1120
N05CD07
ATC
temazepam; oral
4.6
71.9
209
566
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
9.9
69.2
83
92
Z72.1
ICD-10 Finland
Alcohol use
13.4
69.1
67
54
N06AB04
ATC
citalopram; systemic
3.8
68.1
281
977
S01.0
ICD-10 Finland
Open wound of scalp
4.9
67.0
174
429
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.6
65.4
99
146
N05BA01
ATC
diazepam; systemic, rectal
4.2
64.6
208
605
N05BA04
ATC
oxazepam; oral
3.5
61.6
314
1240
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.6
60.9
166
424
R41.0
ICD-10 Finland
Disorientation, unspecified
8.2
60.4
84
112
N06AX11
ATC
mirtazapine; oral
3.2
60.0
386
1749
A28
ICPC
Limited function/disability NOS
3.6
58.3
258
928
A06AD11
ATC
lactulose; oral
3.7
57.7
231
777
N05AD01
ATC
haloperidol; systemic
8.4
56.5
77
100
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
8.9
56.4
73
89
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
10.9
56.1
62
61
C07AA05
ATC
propranolol; systemic
3.6
55.3
233
809
F10.03
ICD-10 Finland
Alcohol-related acute intoxication with delirium
23.3
54.7
40
18
N05AX08
ATC
risperidone; systemic
5.0
53.0
125
282
N05CF01
ATC
zopiclone; oral
3.0
52.8
380
1806
F03
ICD-10 Finland
Unspecified dementia
7.2
50.5
78
117
W19
ICD-10 Finland
Unspecified fall
4.2
50.3
157
441
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.1
49.7
78
119
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
49.6
359
1698
L28
ICPC
Limited function/disability (L)
3.3
49.2
247
949
V03AA01, ,
ATC
8.4
49.2
66
84
S06.0
ICD-10 Finland
Concussion
3.9
46.9
163
493
E87.6
ICD-10 Finland
Hypokalaemia
6.1
45.9
84
150
N05AB01
ATC
dixyrazine; systemic
10.0
45.5
53
56
K70.0
ICD-10 Finland
Alcoholic fatty liver
13.2
45.5
44
35
S42.2
ICD-10 Finland
Fracture of upper end of humerus
6.2
42.6
76
132
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
11.9
42.5
44
39
N05AA02
ATC
levomepromazine; systemic
5.6
41.7
84
164
SPAT1265
SPAT
Breathalyser
11.9
40.7
42
37
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.8
38.6
92
208
N05AD03
ATC
melperone; systemic
11.3
38.5
41
38
G72.8
ICD-10 Finland
Other specified myopathies
8.2
38.2
52
67
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
14.9
36.7
33
23
S72.0
ICD-10 Finland
Fracture of neck of femur
5.5
36.5
74
145
N03AF01
ATC
carbamazepine; oral, rectal
4.5
35.3
92
223
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.2
35.1
102
269
N05AH03
ATC
olanzapine; systemic
4.5
34.8
90
217
V03AB30, ,
ATC
12.6
34.3
34
28
R53
ICD-10 Finland
Malaise and fatigue
2.6
34.2
260
1220
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
13.2
34.2
33
26
N03AG01
ATC
valproic acid; systemic, rectal
4.6
34.2
87
207
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
5.0
33.8
77
167
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
52.4
33.8
40
8
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.1
33.7
166
618
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
32.7
133
441
N06AB03
ATC
fluoxetine; oral
3.2
31.4
142
502
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
30.7
325
1763
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
29.1
177
736
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.2
28.9
83
216
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
34.1
28.0
36
11
D64.9
ICD-10 Finland
Anaemia, unspecified
2.9
27.9
156
619
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
4.7
27.6
66
149
P20
ICPC
Memory disturbance
2.8
26.9
154
618
SPAT1254
SPAT
Administration of medicine
2.8
26.8
163
675
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.8
26.6
85
239
R27.0
ICD-10 Finland
Ataxia, unspecified
26.8
26.4
36
14
N03AX14
ATC
levetiracetam; systemic
5.4
26.3
53
103
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.6
26.2
95
291
K85
ICD-10 Finland
Acute pancreatitis
6.4
25.6
43
70
SPAT1234
SPAT
Support of social functional capacity
4.1
25.5
74
194
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
23.4
25.4
36
16
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
6.4
25.1
42
68
E51.2
ICD-10 Finland
Wernicke encephalopathy
40.2
25.0
31
8
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
6.6
25.0
41
65
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.1
25.0
118
425
G40.51
ICD-10 Finland
Epileptic seizures related to alcohol
92.9
24.8
27
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.8
24.6
78
218
S82.6
ICD-10 Finland
Fracture of lateral malleolus
3.7
24.5
82
238
N06AB10
ATC
escitalopram; oral
2.5
24.2
174
781
F10.8
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Other mental and behavioural disorders
57.8
24.2
28
5
R26.0
ICD-10 Finland
Ataxic gait
32.1
23.8
31
10
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.8
23.5
76
215
SPAT1216
SPAT
Assessment of functional ability
2.5
23.4
169
759
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
22.8
227
1174
F10
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol
41.4
22.8
28
7
N05AF03
ATC
chlorprothixene; systemic
5.8
22.8
42
75
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
8.4
22.7
30
37
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
9.6
22.7
27
29
C03CA01
ATC
furosemide; systemic
2.1
22.7
331
1991
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
22.7
141
588
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
22.6
208
1040
A98
ICPC
Health maint/preventive medicine
0.4
22.2
616
7230
R18
ICD-10 Finland
Ascites
5.7
22.2
42
77
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
8.7
22.0
28
33
N06AX03
ATC
mianserin; oral
3.9
21.8
66
178
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.2
21.8
38
64
2910A
ICD-9 Finland
Alcoholic psychoses, Alcohol withdrawal delirium
82.4
21.8
24
*
F10.23
ICD-10 Finland
Alcohol dependence currently abstinent but using aversion-inducing or inhibitory medication
27.2
21.5
29
11
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.5
21.3
158
716
N05BE01
ATC
buspirone; oral
4.8
21.0
49
108
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.2
20.6
43
86
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
49.3
20.2
24
5
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
4.5
20.2
51
120
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.4
20.2
75
233
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.7
20.1
47
104
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.2
19.8
82
272
S22.3
ICD-10 Finland
Fracture of rib
2.8
19.6
106
410
OAB43, ,
SPAT
0.1
19.4
12
998
SPAT1227
SPAT
Substance abuse rehabilitation
16.0
19.4
31
20
P17
ICPC
Tobacco abuse
8.1
19.2
26
33
S72.1
ICD-10 Finland
Pertrochanteric fracture
5.6
19.2
37
69
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.6
19.0
120
502
F10.4
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state with delirium
35.2
19.0
24
7
SPAT1307
SPAT
Psychosocial counselling and guidance
4.7
18.9
45
101
F10.74
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol otherwise permanently impaired intelligence
71.6
18.8
21
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
18.8
146
674
G31.0
ICD-10 Finland
Circumscribed brain atrophy
102.4
18.6
20
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
6.6
18.5
30
47
E86
ICD-10 Finland
Volume depletion
4.4
18.3
46
108
N06AX16
ATC
venlafaxine; oral
2.5
18.2
124
538
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
5.4
18.1
36
69
K92.1
ICD-10 Finland
Melaena
3.1
17.9
81
283
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
7.4
17.9
26
36
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
+∞
17.8
17
*
A04
ICPC
Weakness/tiredness general
2.4
17.8
141
656
F10.06
ICD-10 Finland
Alcohol-related acute intoxication with seizures
183.7
17.6
18
*
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
4.3
17.4
46
112
ZXD05
NOMESCO Finland
Urgent procedure
2.0
17.4
281
1718
N28
ICPC
Limited function/disability (N)
5.8
17.4
32
57
N05BA06
ATC
lorazepam; systemic, sublingual
3.4
17.3
66
208
S00.0
ICD-10 Finland
Superficial injury of scalp
4.8
17.2
39
84
T74.1
ICD-10 Finland
Physical abuse
6.8
17.1
27
41
S42.0
ICD-10 Finland
Fracture of clavicle
4.1
17.0
48
123
N06AB06
ATC
sertraline; oral
2.7
17.0
99
397
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
3.6
16.9
57
166
SPAT1229
SPAT
Assessment of need for aid
2.9
16.9
84
310
F10.59
ICD-10 Finland
Alcohol psychosis, mixed type
173.3
16.6
17
*
S06.3
ICD-10 Finland
Focal brain injury
6.3
16.5
28
46
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
3.9
16.3
48
127
C03DA01
ATC
spironolactone; oral
2.2
16.0
148
734
P70
ICPC
Dementia
6.8
15.8
25
38
F10.6
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Amnesic syndrome
61.2
15.8
18
*
R11
ICD-10 Finland
Nausea and vomiting
2.8
15.6
83
317
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
15.5
90
360
Z02.7
ICD-10 Finland
Issue of medical certificate
2.8
15.5
80
301
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
6.8
15.4
24
36
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.0
15.3
72
257
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.3
15.2
39
93
S01
ICD-10 Finland
Open wound of head
5.9
15.0
27
47
N06DX01
ATC
memantine; oral
4.0
14.9
43
112
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
14.9
126
2341
S01.8
ICD-10 Finland
Open wound of other parts of head
5.6
14.9
28
51
P29
ICPC
Psychological sympt/compl other
3.4
14.7
55
171
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.1
14.7
63
213
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
14.7
159
836
R25.1
ICD-10 Finland
Tremor, unspecified
4.2
14.7
40
100
N06AA12
ATC
doxepin; systemic
3.0
14.6
65
225
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.5
14.6
100
434
G40
ICD-10 Finland
Epilepsy
12.8
14.4
25
20
P99
ICPC
Psychological disorders other
4.7
14.3
33
72
S22.4
ICD-10 Finland
Multiple fractures of ribs
4.1
14.2
39
98
NBJ62
NOMESCO Finland
Internal fixation of fracture of shoulder or upper arm using plate and screws, humerus
6.5
14.2
23
36
OAA67, ,
SPAT
0.1
14.1
9
574
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
14.1
151
791
M01AH05
ATC
etoricoxib; oral
0.6
13.9
291
4086
S62.3
ICD-10 Finland
Fracture of other metacarpal bone
4.3
13.8
36
87
C10AA07
ATC
rosuvastatin; oral
0.5
13.7
129
2320
N29
ICPC
Neurological sympt/complt other
5.1
13.7
29
59
N03AF02
ATC
oxcarbazepine; oral
3.8
13.5
41
111
N05BA12
ATC
alprazolam; oral
2.4
13.4
96
424
K08.3
ICD-10 Finland
Retained dental root
2.4
13.4
96
424
Z08
ICPC
Social welfare problem
5.7
13.4
25
45
K29.2
ICD-10 Finland
Alcoholic gastritis
18.6
13.4
20
11
G93.4
ICD-10 Finland
Encephalopathy, unspecified
26.2
13.4
18
7
F10.02
ICD-10 Finland
Alcohol-related acute intoxication with other acute clinical complications
26.2
13.4
18
7
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.6
13.3
45
131
SPAT1240
SPAT
Therapeutic discussion
2.6
13.3
78
313
G30.1
ICD-10 Finland
Alzheimer disease with late onset
5.2
13.2
27
53
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
3.8
12.9
39
105
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.8
12.8
65
242
E87.2
ICD-10 Finland
Acidosis
12.5
12.7
22
18
G41.9
ICD-10 Finland
Status epilepticus, unspecified
12.5
12.7
22
18
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.2
12.7
117
577
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.6
12.6
24
44
S82.0
ICD-10 Finland
Fracture of patella
5.3
12.5
25
48
NGJ60
NOMESCO Finland
Internal fixation of fracture of knee or lower leg using intramedullary nail, other or unspecified
6.3
12.5
21
34
S43.0
ICD-10 Finland
Dislocation of shoulder joint
3.3
12.5
47
147
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
4.7
12.4
29
64
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.7
12.4
29
64
OAB48, ,
SPAT
0.2
12.4
9
528
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.9
12.4
58
207
W10
ICD-10 Finland
Fall on and from stairs and steps
2.8
12.3
63
236
2918A
ICD-9 Finland
Alcoholic psychoses, Other specified alcoholic psychosis
38.1
12.2
15
*
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.3
12.2
46
144
Z03
ICPC
Housing/neighbourhood problem
16.2
12.2
19
12
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.6
12.1
71
285
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.5
12.1
81
347
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
12.0
65
251
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
12.0
254
1658
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
4.6
12.0
28
62
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
11.9
81
349
R55
ICD-10 Finland
Syncope and collapse
2.2
11.9
113
562
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.4
11.9
62
1418
N03AB02
ATC
phenytoin; systemic
5.5
11.9
23
43
Z2446
NOMESCO Finland
Social worker
2.7
11.9
68
270
F10.3
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state
11.9
11.9
21
18
SPAT1053
SPAT
Memory test
2.1
11.9
129
677
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
11.9
167
960
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
4.0
11.8
33
84
G30.8
ICD-10 Finland
Other Alzheimer disease
16.7
11.7
18
11
EBA30
NOMESCO Finland
Extraction of root of tooth
2.5
11.7
74
309
R01AD58
ATC
fluticasone, combinations; nasal
0.3
11.7
33
1011
C10AX09
ATC
ezetimibe; oral
0.4
11.6
48
1219
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
121.6
11.5
12
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.1
11.4
49
166
OAA80, ,
SPAT
0.1
11.4
*
366
N06AB05
ATC
paroxetine; oral
2.8
11.4
57
211
SPAT1247
SPAT
Outpatient detoxication and monitoring
12.0
11.4
20
17
R42
ICD-10 Finland
Dizziness and giddiness
1.8
11.3
193
1179
P03
ICPC
Feeling depressed
2.6
11.3
66
265
K20
ICD-10 Finland
Oesophagitis
4.5
11.3
27
61
WYA20
NOMESCO Finland
Home visit
4.8
11.2
25
53
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
11.2
51
179
N02AA05
ATC
oxycodone; systemic
1.8
11.1
189
1151
30310
ICD-8 Finland
Alcoholism, Habitual excessive drinking
8.7
11.1
23
27
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.8
11.0
54
198
TAB00
NOMESCO Finland
Lumbar puncture
3.1
10.9
47
160
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
4.4
10.8
27
63
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
10.8
125
670
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
3.8
10.8
33
90
N07BA03
ATC
varenicline; oral
2.8
10.7
53
195
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.3
10.7
41
130
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
10.7
89
1700
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.2
10.7
28
68
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.7
10.6
33
91
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.3
10.5
81
370
K22.1
ICD-10 Finland
Ulcer of oesophagus
4.0
10.5
30
78
F10.7
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Residual and late-onset psychotic disorder
33.0
10.3
13
*
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
4.5
10.3
25
57
G47.3
ICD-10 Finland
Sleep apnoea
0.5
10.3
88
1667
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
10.2
84
395
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.8
10.1
52
195
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.2
10.1
39
124
ZXD35
NOMESCO Finland
Usual procedure
3.3
10.1
38
119
T51.0
ICD-10 Finland
Toxic effect: Ethanol
14.8
10.0
16
11
WX730
NOMESCO Finland
Conventional respirator
4.3
9.9
25
59
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.3
9.8
77
354
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
5.4
9.7
19
36
XA800
NOMESCO Finland
Neuropsychological investigation
2.8
9.7
48
177
7803A
ICD-9 Finland
General symptoms, Convulsions
8.5
9.6
20
24
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.1
9.6
102
530
K76.7
ICD-10 Finland
Hepatorenal syndrome
15.2
9.5
15
10
SPE90
NOMESCO Finland
Other partial denture
3.7
9.5
30
84
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.6
9.4
31
89
S52.5
ICD-10 Finland
Fracture of lower end of radius
2.3
9.4
71
321
N06AA09
ATC
amitriptyline; systemic
2.2
9.4
80
381
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
22.0
9.4
13
6
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.1
9.3
25
62
R33
ICD-10 Finland
Retention of urine
2.0
9.3
109
587
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.1
9.2
38
126
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
13.9
9.2
15
11
Y94.0
ICD-10 Finland
Accident at home
4.5
9.1
22
50
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
4.7
9.1
21
46
QAB00
NOMESCO Finland
Suture of skin of head or neck
4.7
9.1
21
46
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
4.9
9.1
20
42
F34.1
ICD-10 Finland
Dysthymia
3.1
9.1
37
122
E000001, ,
ATC
1.8
9.0
144
857
J01DA01
ATC
[U] cefalexin
1.6
9.0
481
3878
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.0
9.0
40
139
Z29
ICPC
Social problem NOS
4.3
9.0
23
55
E13.7
ICD-10 Finland
Other specified diabetes mellitus, with multiple complications
18.8
8.9
13
7
G11.9
ICD-10 Finland
Hereditary ataxia, unspecified
24.3
8.9
12
5
N07BB04
ATC
naltrexone; oral
12.7
8.9
15
12
309
Kela drug reimbursment
Nalmefene and naltrexone
8.1
8.9
19
24
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
8.9
128
738
J86.9
ICD-10 Finland
Pyothorax without fistula
4.7
8.9
20
43
OAA65, ,
SPAT
0.2
8.8
10
541
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.6
8.7
28
79
R13
ICD-10 Finland
Dysphagia
2.2
8.7
73
345
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.1
8.7
82
407
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.1
8.7
36
120
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
4.5
8.7
21
48
L82
ICD-10 Finland
Seborrhoeic keratosis
0.4
8.6
44
1027
C10AA05
ATC
atorvastatin; oral
0.6
8.6
231
3192
S42.3
ICD-10 Finland
Fracture of shaft of humerus
4.8
8.6
19
40
R01AD09
ATC
mometasone; nasal
0.6
8.6
150
2306
F05.8
ICD-10 Finland
Other delirium
8.3
8.6
18
22
NFJ52
NOMESCO Finland
Internal fixation of fracture of upper femur with screws and sideplate
11.7
8.6
15
13
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
3.6
8.6
28
80
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.9
8.6
25
66
R01AD12
ATC
fluticasone furoate; nasal
0.5
8.6
73
1396
P01
ICPC
Feeling anxious/nervous/tense
2.4
8.5
57
244
F10.52
ICD-10 Finland
Psychotic alcohol hallucination
20.3
8.5
12
6
S06.2
ICD-10 Finland
Diffuse brain injury
7.5
8.5
19
26
G37.2
ICD-10 Finland
Central pontine myelinolysis
90.9
8.4
9
*
S06.4
ICD-10 Finland
Epidural haemorrhage
90.9
8.4
9
*
P18
ICPC
Medication abuse
12.9
8.4
14
11
NFJ50
NOMESCO Finland
Internal fixation of fracture of neck of femur with nail or screw
12.9
8.4
14
11
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.6
8.4
50
203
WW200, ,
SPAT
0.5
8.4
114
1880
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
8.3
150
924
J01FA10
ATC
azithromycin; systemic
0.6
8.3
215
3002
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
9.6
8.3
16
17
Z04.3
ICD-10 Finland
Examination and observation following other accident
3.9
8.3
24
63
B03BA03
ATC
hydroxocobalamin; parenteral
2.4
8.3
55
235
Z10.0
ICD-10 Finland
Occupational health examination
0.1
8.2
5
331
D10
ICPC
Vomiting
3.1
8.2
34
113
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
8.2
90
472
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.7
8.2
45
175
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.4
8.2
56
243
S82.2
ICD-10 Finland
Fracture of shaft of tibia
4.1
8.1
22
55
5770D
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA ALCOHOLICA NONHAEMORHAGICA]
11.8
8.1
14
12
SPAT1252
SPAT
Overall medication plan or its review
2.3
8.1
63
289
R03BB04
ATC
tiotropium bromide; inhalant
1.9
8.1
113
644
SPAT1241
SPAT
Extensive assessment of psychosocial situation
10.2
8.0
15
15
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
22.3
8.0
11
5
S97
ICPC
Chronic ulcer skin
2.1
8.0
74
365
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
7.9
112
640
EBA00
NOMESCO Finland
Extraction of tooth
1.5
7.9
294
2168
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
13.2
7.9
13
10
Z28
ICPC
Limited function/disability (Z)
13.2
7.9
13
10
A29
ICPC
General symptom/complaint other
1.8
7.9
118
687
SPAT1251
SPAT
Organisation of medication
2.9
7.9
36
127
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.3
7.9
29
90
D07AA02
ATC
hydrocortisone; topical
1.9
7.9
101
560
F60.9
ICD-10 Finland
Personality disorder, unspecified
8.6
7.8
16
19
S70.0
ICD-10 Finland
Contusion of hip
2.7
7.8
42
162
S01.9
ICD-10 Finland
Open wound of head, part unspecified
3.7
7.8
24
66
N18
ICPC
Paralysis/weakness
3.7
7.8
24
66
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
7.7
73
362
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
7.7
108
615
P19
ICPC
Drug abuse
15.2
7.7
12
8
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
15.2
7.7
12
8
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.3
7.7
29
91
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.9
7.7
35
123
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
6.0
7.7
20
34
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
7.7
71
349
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.6
7.6
44
176
Z50.2
ICD-10 Finland
Alcohol rehabilitation
25.3
7.6
10
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
4.2
7.6
20
49
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
3.9
7.6
22
58
L57.0
ICD-10 Finland
Actinic keratosis
0.3
7.5
16
580
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.5
7.5
45
183
WX892
NOMESCO Finland
Monitored bed care
2.0
7.5
78
401
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
4.3
7.5
19
45
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
7.2
7.5
17
24
N06AX21
ATC
duloxetine; oral
2.0
7.5
87
466
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
3.6
7.5
24
68
N03AE01
ATC
clonazepam; systemic
2.4
7.4
50
215
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.4
7.4
53
234
N07
ICPC
Convulsion/seizure
80.8
7.4
8
*
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
7.7
7.4
16
21
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
7.4
46
191
K29.7
ICD-10 Finland
Gastritis, unspecified
2.8
7.4
36
132
L76
ICPC
Fracture: other
3.0
7.3
32
110
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.1
7.3
72
363
D21
ICPC
Swallowing problem
3.9
7.3
21
55
A46
ICD-10 Finland
Erysipelas
1.7
7.3
148
941
N06AB08
ATC
fluvoxamine; oral
3.1
7.3
30
100
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
5.9
7.2
19
33
K86.3
ICD-10 Finland
Pseudocyst of pancreas
7.4
7.2
16
22
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.0
7.2
20
51
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.6
7.2
23
65
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
3.5
7.2
24
70
N06DA03
ATC
rivastigmine; oral, transdermal
3.3
7.2
26
80
G41.0
ICD-10 Finland
Grand mal status epilepticus
20.2
7.1
10
5
9800A
ICD-9 Finland
Toxic effect of alcohol, Ethyl alcohol
20.2
7.1
10
5
J01FF01
ATC
clindamycin; systemic
1.6
7.1
223
1577
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.6
7.1
39
152
R40.2
ICD-10 Finland
Coma, unspecified
6.1
7.1
18
30
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
12.2
7.1
12
10
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
7.1
120
725
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.5
7.1
57
1118
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
7.1
199
1373
R5110, ,
SPAT
2.0
7.1
74
382
N03AX18
ATC
lacosamide; systemic
8.9
7.1
14
16
S82.3
ICD-10 Finland
Fracture of lower end of tibia
3.7
7.1
22
61
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.7
7.1
22
61
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
7.0
38
147
S01.7
ICD-10 Finland
Multiple open wounds of head
7.1
7.0
16
23
SPAT1104
SPAT
Monitoring of emergency patient
2.2
7.0
59
280
F61.0
ICD-10 Finland
Mixed personality disorders
4.4
7.0
17
39
R41.3
ICD-10 Finland
Other amnesia
3.1
7.0
29
97
K86.1
ICD-10 Finland
Other chronic pancreatitis
5.9
6.9
18
31
Y96.9
ICD-10 Finland
Unspecified type of accident
3.6
6.9
22
62
X58
ICD-10 Finland
Exposure to other specified factors
1.7
6.9
121
738
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
2.5
6.9
41
167
A07AA11
ATC
rifaximin; oral
11.0
6.8
12
11
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.6
6.8
161
2322
Z72.8
ICD-10 Finland
Other problems related to lifestyle
16.8
6.8
10
6
Y90.8
ICD-10 Finland
Blood alcohol level of 240 mg/100 ml or more
16.8
6.8
10
6
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.6
6.7
22
63
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
3.6
6.7
22
63
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.4
6.7
23
68
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
0.6
6.7
112
1762
Y04.9
ICD-10 Finland
Assault by bodily force by unknown person
7.3
6.7
15
21
N06AG02
ATC
moclobemide; oral
2.6
6.7
39
157
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.1
6.7
63
313
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.9
6.6
31
111
L75
ICPC
Fracture: femur
5.6
6.6
18
33
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
5.6
6.6
18
33
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.5
6.6
39
158
U70
ICPC
Pyelonephritis/pyelitis
3.9
6.6
19
50
Y94.8
ICD-10 Finland
Other leisure activity accident
3.1
6.5
27
90
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
10.1
6.5
12
12
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
3.7
6.5
20
55
F10.70
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol flashbacks
70.4
6.4
7
*
K70
ICD-10 Finland
Alcoholic liver disease
70.4
6.4
7
*
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.8
6.4
32
119
M17.1
ICD-10 Finland
Other primary gonarthrosis
0.5
6.4
71
1255
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.4
373
2985
N06DA02
ATC
donepezil; oral
2.8
6.4
30
108
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
0.6
6.4
158
2261
R74
ICPC
Upper respiratory infection acute
0.5
6.4
72
1266
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
6.3
90
515
F31.8
ICD-10 Finland
Other bipolar affective disorders
5.2
6.3
18
35
S52.0
ICD-10 Finland
Fracture of upper end of ulna
3.6
6.3
20
56
A02BC02
ATC
pantoprazole; systemic
1.5
6.3
551
4750
S02.00
ICD-10 Finland
Fracture of the upper part of the head closed
9.3
6.3
12
13
I95.1
ICD-10 Finland
Orthostatic hypotension
2.5
6.3
40
168
X99.9
ICD-10 Finland
Assault by sharp object by unknown person
18.2
6.3
9
5
Z72.2
ICD-10 Finland
Drug use
18.2
6.3
9
5
5353A
ICD-9 Finland
Gastritis and duodenitis, Alcoholic gastritis
18.2
6.3
9
5
K86.0
ICD-10 Finland
Alcohol-induced chronic pancreatitis
18.2
6.3
9
5
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
6.3
6
*
F10.50
ICD-10 Finland
Alcohol-related psychosis is schizophrenic
+∞
6.3
6
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
2.8
6.2
31
115
RS110, ,
NOMESCO Finland
26.9
6.2
8
*
G40.59
ICD-10 Finland
Other special epileptic syndromes
26.9
6.2
8
*
F10.51
ICD-10 Finland
Psychotic alcohol paranoia
26.9
6.2
8
*
P74
ICPC
Anxiety disorder/anxiety state
3.0
6.2
27
93
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
0.4
6.2
39
839
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.3
6.2
15
24
OAB42, ,
SPAT
0.4
6.2
26
662
NB6AA
NOMESCO Finland
Humerus X-ray examination
3.4
6.2
21
62
GD1AD
NOMESCO Finland
Thorax CT examination
2.0
6.2
68
358
N06AA06
ATC
trimipramine; systemic
3.0
6.2
26
88
9128
FHL
Open reduction and osteosynthesis
2.7
6.1
31
116
S27.1
ICD-10 Finland
Traumatic haemothorax
7.7
6.1
13
17
F10.22
ICD-10 Finland
Alcohol dependence is currently on clinically controlled discontinuation medication
7.7
6.1
13
17
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
7.7
6.1
13
17
SPAT1243
SPAT
Psychiatric/psychological examination
3.6
6.1
19
53
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.9
6.0
17
44

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
167
229
8.86
119.54
4.5
3.1
35.81
33.63
umol/l
0.47
155
206
156
351
5.23
66.99
2.7
1.8
0.56
0.39
mg/l
2.10
106
182
64
64
10.74
57.30
2.1
1.5
1.75
1.29
promille
1.07
55
53
287
1244
2.99
45.92
2.0
1.7
1193.21
1160.84
nmol/l
0.21
221
965
45
42
11.27
42.06
1.1
1.2
133.66
138.32
nmol/l
0.19
45
42
213
826
3.12
40.95
3.1
2.4
0.18
0.21
g/l
5.63
187
764
531
6868
0.38
37.06
4.5
5.5
1.36
1.35
mmol/l
0.07
480
6340
537
6909
0.38
36.88
4.5
5.6
4.19
4.43
mmol/l
6.05
489
6432
415
2414
2.42
34.36
3.6
2.3
278.05
251.56
u/l
0.25
399
2284
283
1444
2.45
30.65
4.2
4.0
0.75
0.82
mmol/l
13.28
268
1379
566
7013
0.41
30.42
5.1
6.4
2.33
2.59
mmol/l
9.74
516
6489
518
6611
0.43
28.46
3.9
4.7
1.34
1.35
mmol/l
0.07
460
6074
400
2426
2.24
28.41
5.9
4.9
—
—
—
0
0
37
46
8.37
27.93
2.5
1.7
—
—
—
0
0
396
2456
2.16
25.89
4.4
2.9
60.85
92.45
u/l
0.48
376
2297
233
1173
2.37
25.29
4.3
7.5
0.99
1.03
mmol/l
1.46
222
1103
64
153
4.45
24.88
2.1
1.3
54.90
61.01
mmol/l
0.46
51
124
126
2687
0.37
23.56
3.7
3.5
—
—
—
0
0
102
349
3.19
23.53
2.2
2.4
272.26
556.48
ug/l
1.10
95
333
491
3402
2.07
22.90
6.0
6.1
32.28
35.00
g/l
16.70
467
3208
46
100
4.81
20.07
5.5
5.8
334.50
356.16
umol/l
0.35
38
89
42
85
5.15
19.89
3.2
1.4
—
—
—
0
0
248
3855
0.49
18.95
3.4
4.6
19.75
21.49
%
1.13
116
1947
340
2187
1.93
18.31
2.1
1.8
16.97
19.69
nmol/l
3.35
311
1842
163
2911
0.45
18.30
2.6
3.3
0.67
0.75
ug/l
0.75
128
1940
527
3921
1.93
18.08
13.7
16.5
1.22
1.30
inr
3.58
459
3280
182
3111
0.47
18.00
1.9
2.0
1.30
1.37
mmol/l
0.41
154
2551
346
4780
0.53
17.53
4.1
5.7
3.37
2.86
ug/l
0.18
305
4332
567
6745
0.51
17.47
7.3
7.1
39.99
40.28
mmol/mol
0.23
518
6290
575
6799
0.51
17.07
5.3
5.5
6.36
6.13
mmol/l
1.85
511
6218
471
3418
1.86
17.02
9.7
8.1
1.18
1.20
mmol/l
5.58
445
3173
540
4101
1.89
16.80
9.4
7.7
14.84
12.72
umol/l
1.57
520
3938
36
74
5.04
16.75
3.0
2.3
—
—
—
0
0
59
180
3.45
16.29
1.2
1.3
460.87
605.71
mg/l
2.35
54
166
307
1974
1.88
16.07
2.6
2.3
3.17
2.88
mg/l
0.97
273
1700
43
107
4.18
15.86
3.2
1.6
—
—
—
0
0
164
865
2.11
15.08
5.1
4.0
1.02
1.83
mmol/l
1.39
142
732
43
112
3.99
14.92
3.3
1.5
—
—
—
0
0
43
114
3.92
14.57
3.6
1.5
—
—
—
0
0
166
892
2.07
14.48
5.1
4.0
5.60
5.84
kpa
2.06
161
866
663
7421
0.49
14.47
44.7
28.2
126.55
137.62
g/l
45.65
650
7335
663
7421
0.49
14.47
44.3
28.0
7.60
6.90
e9/l
11.23
645
7234
172
937
2.05
14.46
2.0
1.8
—
—
—
0
0
663
7420
0.49
14.43
44.2
27.9
93.31
91.69
fl
12.09
651
7333
663
7420
0.49
14.43
44.1
27.9
31.19
30.61
pg
9.24
651
7332
663
7420
0.49
14.43
44.3
28.0
4.12
4.53
e12/l
55.67
644
7236
663
7420
0.49
14.43
45.8
28.8
37.78
40.91
%
35.25
650
7325
663
7419
0.49
14.38
44.3
28.0
239.88
236.37
e9/l
0.52
646
7261
249
1554
1.86
13.96
1.8
1.8
462.50
28560913.86
pmol/l
1.45
210
1306
50
152
3.43
13.88
1.2
1.5
130.51
910.76
e6/l
0.52
39
117
220
1324
1.90
13.79
2.4
2.8
2.12
2.24
g/l
1.62
198
1236
42
114
3.83
13.78
3.1
1.5
—
—
—
0
0
364
2553
1.75
13.73
5.2
3.7
74.27
37.08
u/l
0.81
334
2412
49
150
3.41
13.46
1.2
1.4
13.27
69.63
e6/l
0.70
37
110
647
7274
0.52
13.41
17.5
13.4
29.10
28.59
u/l
0.18
628
7072
230
1418
1.86
13.31
2.4
2.9
10.49
13.12
umol/l
6.33
210
1334
63
229
2.89
12.99
1.2
1.2
104.00
89.44
titre
—
5
18
164
910
2.00
12.99
4.0
3.1
15.70
9.28
umol/l
1.54
145
833
148
797
2.04
12.72
12.3
11.3
—
—
—
0
0
40
113
3.67
12.40
3.4
1.5
—
—
—
0
0
662
7359
0.52
12.18
38.8
24.7
79.91
86.62
umol/l
4.25
651
7284
9
514
0.17
11.94
1.0
1.4
—
—
—
0
0
203
1241
1.84
11.90
2.5
2.9
22.09
23.90
%
0.70
183
1169
139
749
2.03
11.89
4.1
3.2
4.47
4.49
kpa
0.03
133
729
185
1101
1.87
11.80
11.0
9.9
0.68
0.79
mmol/l
0.11
153
914
24
47
5.23
11.79
1.0
1.1
741.50
698.65
ng/l
0.20
18
26
24
47
5.23
11.79
1.0
1.1
317.56
210.20
ng/l
1.08
18
25
45
143
3.27
11.67
1.2
1.3
—
—
—
0
0
60
226
2.78
11.59
1.7
1.5
264.12
256.61
ug/g
0.08
30
137
176
1043
1.87
11.34
2.2
2.7
2.08
1.79
%
2.04
161
945
158
913
1.90
10.98
5.0
4.1
7.38
7.38
ph
0.16
97
539
435
3340
1.63
10.76
2.8
2.2
89.71
93.19
pmol/l
0.83
286
1916
482
3801
1.63
10.66
9.9
8.8
1.19
1.20
mmol/l
4.57
429
3298
131
719
1.97
10.58
4.6
2.7
31.48
42.23
u/l
0.91
115
613
16
10
16.27
10.37
1.0
1.3
61.31
82.60
ug/l
—
16
10
276
1906
1.67
10.31
3.6
3.1
—
—
—
0
0
93
454
2.18
10.27
1.6
1.8
1.55
1.58
g/l
0.11
75
398
117
630
2.00
9.95
4.1
3.8
5.13
5.11
kpa
0.10
112
609
179
1109
1.78
9.86
11.3
10.0
7.41
7.41
ph
0.35
116
618
425
5198
0.63
9.71
4.4
4.6
—
7770.85
—
0
13
114
616
1.98
9.59
4.2
3.8
7.41
7.42
ph
0.40
95
521
33
98
3.46
9.53
1.5
1.5
—
—
—
0
0
565
4711
1.61
9.29
7.9
3.7
104.83
60.60
u/l
7.78
539
4427
310
2256
1.59
9.14
4.2
4.9
7.40
7.40
ph
2.41
237
1621
19
38
5.09
9.13
1.9
1.3
89.22
68.47
umol/l
—
9
19
15
12
12.70
8.89
2.3
1.1
—
—
—
0
0
396
3070
1.55
8.74
5.6
4.2
35.87
98.67
ng/l
1.46
338
2386
119
673
1.90
8.74
2.0
2.3
397.44
374.67
nmol/l
0.48
106
629
189
1227
1.70
8.72
2.5
2.3
—
—
—
0
0
149
906
1.78
8.66
1.6
1.6
—
—
—
0
0
334
2501
1.56
8.57
3.1
2.8
—
—
—
0
0
224
1546
1.61
8.07
3.2
3.2
481.98
555.84
mosm/kgh2o
3.30
203
1351
25
69
3.70
8.06
1.5
1.4
—
—
—
0
0
323
2426
1.54
8.05
2.5
3.9
2.33
2.34
mmol/l
0.40
279
2202
634
6994
0.62
7.80
27.6
16.9
—
—
—
0
0
124
740
1.79
7.64
1.6
3.0
65.92
66.30
g/l
0.18
113
690
139
864
1.73
7.43
4.8
9.1
9.46
10.74
mmol/l
0.92
131
835
478
5578
0.67
7.42
40.1
23.9
332.57
333.34
g/l
0.89
472
5551
147
931
1.70
7.34
12.0
11.1
116.19
121.81
g/l
2.32
147
907
127
774
1.76
7.27
1.6
1.6
—
—
—
0
0
18
29
6.32
7.27
2.1
1.8
553.17
5262.44
e6/l
1.25
12
16
16
22
7.39
7.21
1.6
1.5
11.14
26.11
g/l
—
10
16
12
10
12.15
7.09
1.7
1.3
—
—
mmol/l
—
0
0
7
337
0.20
7.05
1.0
1.2
—
—
—
0
0
662
7199
0.62
7.01
40.1
23.0
3.94
4.02
mmol/l
10.39
649
7061
29
97
3.06
6.98
1.4
1.7
—
—
—
0
0
20
53
3.84
6.84
1.1
1.1
—
—
—
0
0
662
7182
0.63
6.58
40.5
22.7
137.92
139.70
mmol/l
23.42
648
7052
34
129
2.70
6.55
1.1
1.1
1.65
1.54
g/l
0.84
28
118
536
4580
1.47
6.55
6.0
4.5
2523.85
1003.31
e6/l
0.32
20
70
131
829
1.69
6.53
2.1
2.8
72.80
69.54
e9/l
0.39
97
627
201
1416
1.55
6.46
2.6
3.4
2.48
2.45
mmol/l
1.83
176
1279
29
102
2.91
6.42
1.6
1.4
117487.89
83189.87
e6/l
0.14
18
54
49
226
2.24
6.25
2.7
3.1
61.10
61.46
%
0.03
44
221
59
1092
0.51
6.12
2.0
2.4
14.95
13.50
nmol/l
0.54
44
982
243
1807
1.49
6.00
3.1
2.8
4.67
3.45
e6/l
1.60
228
1654
77
430
1.87
5.87
4.6
3.9
—
—
—
0
0
16
30
5.42
5.86
2.3
1.6
—
—
—
0
0
84
483
1.82
5.84
4.3
2.8
1.74
1.24
%
2.37
84
483
115
728
1.67
5.71
1.5
1.7
—
—
—
0
0
31
121
2.62
5.68
1.6
1.4
24150.17
1293.82
e6/l
0.76
24
83
9
327
0.27
5.57
1.0
1.1
—
—
—
0
0
95
578
1.73
5.46
9.7
8.4
23.29
24.37
mmol/l
1.43
95
550
148
1011
1.56
5.38
1.4
1.3
—
—
—
0
0
96
590
1.71
5.32
1.6
2.7
—
—
—
0
0
322
2572
1.41
5.29
4.6
6.7
—
—
—
0
0
81
475
1.78
5.29
4.4
2.7
0.60
0.63
%
0.41
81
475
10
386
0.25
5.28
1.2
1.3
—
—
—
0
0
221
2863
0.69
5.21
3.5
3.6
94.52
56.01
mg/l
1.43
150
1982
58
307
1.96
5.20
5.8
4.0
2.39
1.42
mmol/l
1.66
58
302
32
133
2.46
5.19
1.0
1.0
—
—
—
0
0
22
76
2.95
5.06
1.2
1.2
—
—
—
0
0
98
623
1.65
4.79
1.7
2.5
12.36
10.92
g/l
1.50
90
579
26
102
2.60
4.75
1.6
1.4
—
—
—
0
0
527
4627
1.37
4.63
9.6
6.1
6.96
6.87
mmol/l
0.44
514
4443
70
411
1.77
4.57
4.7
3.5
24.54
24.95
mmol/l
0.44
70
394
15
44
3.45
4.48
1.1
1.0
—
—
—
0
0
30
130
2.36
4.48
1.2
1.1
—
—
—
0
0
80
493
1.69
4.41
1.6
1.8
1.79
1.46
g/l
0.63
74
457
233
2928
0.72
4.40
4.1
4.3
16.31
9.17
mg/mmol
1.33
155
1957
36
171
2.15
4.35
5.6
6.0
2.73
2.62
mmol/l
0.08
29
122
106
708
1.57
4.24
4.7
4.6
7.37
7.36
ph
0.32
87
531
348
2901
1.34
4.11
2.5
2.4
69.43
76.50
nmol/l
3.38
304
2595
22
86
2.60
4.08
1.2
1.3
21.14
12.56
u/l
0.52
22
79
244
1928
1.37
4.07
3.1
2.7
—
—
—
0
0
41
212
1.98
3.98
3.9
4.3
—
—
—
0
0
216
2709
0.73
3.92
1.9
2.2
—
—
—
0
0
5
205
0.24
3.87
2.4
1.8
—
—
—
0
0
23
97
2.41
3.67
1.9
2.0
9.73
10.44
%
0.28
23
97
15
54
2.81
3.26
1.5
1.3
—
—
—
0
0
308
2588
1.30
3.25
4.3
3.7
27.58
114.09
e6/l
2.13
263
2015
39
214
1.86
3.23
2.6
2.4
128.87
131.51
g/l
0.19
30
169
7
219
0.31
3.23
2.0
2.2
13.46
12.47
mg/l
—
7
204
437
3850
1.28
3.17
4.9
6.8
0.19
0.20
e9/l
0.80
375
3347
71
465
1.58
3.13
1.4
1.6
—
—
—
0
0
11
30
3.70
3.09
1.2
1.1
0.49
0.48
ratio
—
5
17
612
5648
1.31
3.00
11.4
9.4
90.52
81.29
u/l
5.05
590
5386
19
82
2.35
2.93
1.1
1.1
—
—
—
0
0
21
426
0.48
2.90
1.1
1.3
—
—
—
0
0
424
3751
1.26
2.86
4.8
6.6
0.04
0.04
e9/l
0.01
363
3189
329
2824
1.27
2.86
4.8
4.2
82.98
117.15
e6/l
0.48
260
2088
423
3742
1.26
2.85
4.8
6.6
0.68
0.62
e9/l
3.91
361
3172
246
2919
0.78
2.78
3.4
3.5
6.83
8.29
mmol/l
4.94
198
2474
17
363
0.46
2.72
1.2
1.9
61.32
40.70
nmol/l
1.23
17
346
464
4175
1.25
2.61
6.8
10.6
5.01
4.25
e9/l
5.28
398
3611
28
149
1.91
2.59
1.3
1.2
—
—
—
0
0
48
302
1.63
2.53
1.3
2.8
10.20
10.67
g/l
0.47
41
274
575
6154
0.79
2.51
5.1
4.7
2.06
2.03
mu/l
0.23
523
5579
15
63
2.41
2.47
2.6
2.6
8.73
7.87
mmol/l
0.30
15
63
391
3469
1.24
2.44
5.1
7.0
9.64
9.28
%
1.43
374
3252
0
64
0.00
2.43
0.0
3.1
—
36.26
—
0
31
390
3461
1.24
2.42
5.1
6.9
0.66
0.65
%
0.02
375
3244
388
3448
1.23
2.36
5.0
6.8
60.16
58.05
%
2.68
375
3295
350
3082
1.23
2.31
3.2
3.1
239.74
189.20
ug/l
0.49
323
2861
423
3803
1.23
2.27
4.9
6.7
1.67
1.97
e9/l
3.51
368
3336
394
3519
1.23
2.25
5.1
7.0
23.16
26.35
%
7.11
381
3335
51
336
1.55
2.25
1.2
1.5
—
45.40
—
0
7
49
729
0.65
2.25
1.8
2.5
219.46
145.70
ug/g
0.31
35
598
167
1353
1.29
2.24
1.3
1.2
1.17
1.90
u/ml
0.80
38
385
196
1622
1.27
2.23
4.3
3.8
1.02
1.02
kg/l
2.49
148
1093
14
60
2.36
2.22
1.2
1.1
213.89
370.75
nmol/l
—
9
51
388
3463
1.22
2.22
5.1
6.9
2.66
2.87
%
0.98
372
3247
249
2120
1.25
2.22
4.6
3.9
0.00
0.01
estimate
0.78
80
735
158
1273
1.30
2.21
1.5
1.5
4.23
2.76
g/l
6.06
95
796
118
916
1.34
2.16
1.4
1.3
767.27
432.56
titre
0.54
22
199
6
14
4.31
2.15
1.2
2.2
31.83
16.08
umol/l
—
6
14
15
68
2.23
2.12
2.1
2.2
—
—
—
0
0
334
2948
1.22
2.11
3.6
3.4
6.50
6.17
ph
6.22
185
1661
10
231
0.43
2.02
1.1
1.1
—
—
—
0
0
259
2241
1.23
1.96
4.1
3.5
0.63
0.50
e6/l
0.34
213
1679
6
16
3.77
1.93
1.2
1.1
—
—
—
0
0
74
989
0.72
1.92
1.2
1.4
—
—
—
0
0
77
571
1.38
1.90
14.6
13.3
15.09
15.93
%
1.96
77
549
80
1054
0.73
1.90
1.3
1.3
12.52
12.50
u/ml
0.00
18
407
0
51
0.00
1.89
0.0
5.5
—
20.36
—
0
18
244
2800
0.82
1.88
5.3
3.9
—
0.75
—
0
8
177
2098
0.80
1.86
1.4
1.3
—
—
—
0
0
391
3546
1.19
1.77
3.5
3.1
—
—
estimate
—
0
0
20
112
1.80
1.65
1.2
1.1
19.57
23.82
iu/ml
—
7
22
30
190
1.60
1.62
1.1
1.6
—
—
—
0
0
654
6811
0.82
1.59
32.6
18.8
32.96
27.92
mg/l
2.71
616
5710
42
289
1.48
1.58
1.4
1.3
—
—
—
0
0
71
541
1.34
1.52
2.9
4.6
108.60
101.56
ng/l
0.15
58
481
34
229
1.51
1.43
1.7
1.6
12.92
20.16
u/ml
—
5
51
249
2208
1.18
1.40
6.2
6.8
—
—
—
0
0
52
695
0.73
1.39
1.4
1.4
—
—
—
0
0
76
595
1.30
1.36
4.6
4.7
1.22
1.22
mmol/l
0.32
70
519
10
47
2.14
1.34
3.0
2.7
—
—
—
0
0
136
1602
0.82
1.33
3.8
5.1
—
—
—
0
0
6
24
2.51
1.30
3.7
3.7
2959.67
5.29
ug/l
—
6
24
512
4822
1.16
1.29
5.1
4.5
—
2.40
—
0
9
71
897
0.77
1.29
1.4
1.3
—
—
—
0
0
6
25
2.41
1.24
1.2
1.0
—
—
—
0
0
33
229
1.46
1.23
4.5
3.7
10.23
1.81
index
0.44
13
139
405
3761
1.15
1.22
4.1
3.8
13.22
2.12
estimate
0.39
87
827
30
429
0.69
1.21
2.8
2.9
—
—
—
0
0
400
3713
1.15
1.21
4.0
3.8
0.00
0.00
estimate
-0.00
89
825
95
1145
0.81
1.17
1.3
1.3
76.24
35.11
iu/ml
0.48
23
355
42
309
1.38
1.16
1.8
4.0
64.85
75.43
mg/l
0.21
31
263
42
309
1.38
1.16
1.8
4.0
46.06
115.40
mg/l
0.74
32
265
20
128
1.58
1.09
2.7
3.0
—
—
—
0
0
177
1559
1.17
1.08
5.8
4.2
409.36
452.12
ng/l
0.08
157
1318
7
33
2.13
1.05
1.0
1.7
41.41
39.91
g/l
—
7
33
162
1423
1.17
1.02
3.8
3.2
1.77
0.96
e6/l
1.34
86
812
38
282
1.36
1.02
1.9
3.8
2.48
4.08
ratio
0.38
16
165
151
1323
1.17
0.99
3.9
3.4
2.41
1.07
e6/l
1.25
73
713
286
2628
1.13
0.96
3.2
3.4
2538.10
1504.07
ng/l
1.28
247
2295
0
31
0.00
0.96
0.0
8.5
—
62.07
—
0
23
402
3779
1.12
0.92
4.1
3.8
0.00
0.42
estimate
0.53
79
749
34
256
1.34
0.86
1.1
1.1
—
42.20
—
0
5
6
32
1.88
0.82
1.0
1.0
2209.50
1472.53
miu/ml
—
6
32
5
98
0.51
0.78
1.0
1.2
—
—
—
0
0
7
124
0.56
0.78
1.0
1.2
—
202.84
—
0
45
0
27
0.00
0.77
0.0
1.4
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
7.50
—
0
8
80
936
0.84
0.77
2.4
3.3
9.24
5.24
e9/l
0.39
61
820
30
228
1.33
0.73
2.0
2.5
164.75
120.45
ug/min
0.23
12
137
183
2006
0.89
0.73
4.6
3.4
0.01
0.04
estimate
0.32
69
632
10
158
0.63
0.71
1.7
1.9
—
—
—
0
0
52
432
1.22
0.65
2.5
2.0
2.99
1.52
ug/l
0.49
47
388
6
101
0.59
0.62
1.0
1.3
—
—
—
0
0
6
104
0.57
0.62
1.7
1.9
2.84
5.02
mmol/24h
—
6
89
10
63
1.59
0.62
2.0
2.8
16.71
16.06
%
—
10
63
55
463
1.20
0.61
1.1
1.2
—
—
—
0
0
13
88
1.48
0.61
1.5
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
31.25
—
0
16
0
22
0.00
0.59
0.0
1.4
—
27.95
—
0
22
0
22
0.00
0.59
0.0
2.3
—
2.61
—
0
22
8
53
1.51
0.58
3.5
4.5
1.00
0.92
index
—
8
53
12
173
0.69
0.58
1.0
1.1
—
—
—
0
0
66
569
1.17
0.57
5.3
4.0
—
—
—
0
0
169
1554
1.11
0.57
1.9
1.8
1.95
1.48
mg/l
0.80
138
1223
10
149
0.67
0.57
1.5
2.6
—
—
—
0
0
84
741
1.15
0.55
3.0
2.5
6.21
8.14
ug/l
0.84
75
666
308
3242
0.92
0.54
16.0
12.9
0.00
0.00
e9/l
0.31
240
2629
26
327
0.79
0.54
1.4
1.3
—
—
—
0
0
19
143
1.34
0.53
1.6
5.1
4.76
10.22
pmol/l
5.83
19
143
106
954
1.13
0.52
1.5
1.6
—
—
—
0
0
7
46
1.53
0.48
1.0
1.2
87.43
99.15
pmol/l
—
7
46
7
46
1.53
0.48
2.0
1.6
—
—
—
0
0
34
407
0.83
0.47
1.6
1.3
525.37
256.57
u/ml
1.00
34
379
38
319
1.20
0.46
2.1
1.8
—
—
—
0
0
5
31
1.62
0.43
1.0
2.0
—
—
—
0
0
5
33
1.52
0.41
1.4
1.1
1.13
1.08
ratio
—
5
27
0
16
0.00
0.41
0.0
2.5
—
1.17
—
0
16
5
34
1.47
0.40
3.6
2.5
0.55
0.61
mmol/l
—
5
34
0
19
0.00
0.39
0.0
1.1
—
0.41
—
0
6
16
124
1.30
0.39
2.1
3.0
5.38
4.54
e9/l
0.40
16
124
43
373
1.16
0.38
1.8
3.8
23.10
10928.33
u/ml
0.85
38
318
12
89
1.35
0.38
2.5
4.9
—
—
—
0
0
31
363
0.85
0.36
2.1
2.3
—
—
—
0
0
11
82
1.35
0.34
1.4
1.2
—
—
—
0
0
66
728
0.90
0.33
1.4
1.5
—
—
—
0
0
18
219
0.82
0.31
2.1
1.6
18474.82
13058.69
e6/l
0.40
11
154
11
84
1.31
0.30
1.4
2.9
1476.09
1217.02
mg
0.18
11
84
49
542
0.90
0.27
3.0
2.5
6.23
6.05
ph
0.60
39
369
21
177
1.19
0.27
1.4
1.1
—
—
—
0
0
19
160
1.19
0.25
2.3
2.9
62.62
58.25
%
0.83
19
160
37
330
1.13
0.25
1.5
1.2
—
—
—
0
0
23
198
1.17
0.25
10.5
10.4
12.04
11.48
mmol/l
0.39
23
176
23
198
1.17
0.25
10.5
10.4
102.83
105.49
mmol/l
0.94
23
176
12
96
1.25
0.24
1.1
1.1
—
—
—
0
0
36
402
0.89
0.24
9.0
7.1
0.88
0.85
%
0.17
36
374
65
701
0.92
0.23
2.0
2.1
0.00
0.02
estimate
0.50
15
148
5
38
1.32
0.23
1.2
1.5
8.80
2.48
u/field
—
5
27
19
162
1.18
0.23
4.4
3.8
21.78
31.17
mg/l
0.95
11
116
5
39
1.28
0.23
1.2
1.2
825.60
225.31
iu/ml
—
5
39
17
200
0.85
0.23
1.0
1.2
—
—
—
0
0
18
153
1.18
0.22
1.9
1.6
—
—
—
0
0
5
42
1.19
0.21
17.4
16.9
1177.20
1459.62
nmol/l
—
5
42
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.3
—
16.20
—
0
10
0
10
0.00
0.21
0.0
2.8
—
0.62
—
0
10
0
10
0.00
0.21
0.0
1.1
—
37.63
—
0
10
0
10
0.00
0.21
0.0
4.3
—
—
—
0
0
12
98
1.23
0.21
1.2
2.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
117.29
—
0
7
0
13
0.00
0.21
0.0
1.0
—
91.08
—
0
13
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
6
50
1.20
0.19
1.3
1.0
—
—
—
0
0
30
270
1.12
0.19
1.2
1.5
—
—
—
0
0
10
81
1.24
0.19
1.4
1.2
—
—
—
0
0
8
69
1.16
0.16
1.1
1.2
—
—
—
0
0
6
80
0.75
0.15
2.0
2.4
—
—
—
0
0
10
83
1.21
0.15
1.4
1.6
28.15
41.97
ng/l
—
10
83
14
121
1.16
0.15
1.4
1.7
—
—
—
0
0
14
121
1.16
0.15
1.4
1.7
—
—
—
0
0
14
121
1.16
0.15
1.4
1.7
—
—
—
0
0
14
121
1.16
0.15
1.4
1.7
—
—
—
0
0
19
170
1.12
0.13
2.5
3.1
0.83
0.86
nmol/l
0.12
12
140
32
297
1.08
0.12
2.3
3.8
706.00
311.96
mg/l
0.79
11
141
22
241
0.91
0.12
1.5
1.2
—
1.21
—
0
17
17
155
1.10
0.09
1.3
1.2
—
—
—
0
0
72
696
1.04
0.08
2.8
4.7
0.55
0.60
%
0.12
21
231
73
707
1.04
0.08
3.4
5.1
0.00
0.10
%
1.51
22
198
14
127
1.10
0.08
1.8
1.9
7.88
4.65
iu/l
—
5
50
8
75
1.07
0.07
1.0
1.2
—
—
—
0
0
40
383
1.05
0.07
2.0
2.3
0.00
2.16
estimate
—
9
116
11
99
1.11
0.06
3.5
2.8
1.19
1.19
mmol/l
0.01
11
99
31
325
0.95
0.06
2.7
4.0
4.16
4.48
pmol/l
0.77
25
293
18
169
1.07
0.05
1.1
1.5
—
—
—
0
0
68
664
1.03
0.05
3.9
3.1
175.79
228.60
ng/l
0.62
63
606
92
904
1.02
0.04
2.6
4.7
9.45
28.17
ug/l
1.03
82
755
491
4929
0.99
0.03
3.7
3.7
14.97
14.90
pmol/l
0.26
436
4453
11
102
1.08
0.03
3.5
2.8
105.36
105.42
mmol/l
0.01
11
102
11
102
1.08
0.03
3.5
2.8
4.29
4.10
mmol/l
0.43
11
102
11
103
1.07
0.02
3.0
2.4
—
—
—
0
0
225
2239
1.01
0.01
2.7
3.1
370.37
368.03
umol/l
0.10
193
1965
43
437
0.98
0.01
8.2
6.8
2.30
1.65
%
2.20
43
407
69
697
0.99
0.01
3.5
4.9
0.14
0.11
%
0.07
22
215
31
316
0.98
0.00
1.1
1.2
70.12
155.93
u/ml
0.90
13
111
73
736
0.99
0.00
3.4
4.8
0.73
0.87
%
0.23
24
253
24
235
1.02
0.00
15.2
11.5
—
—
—
0
0
27
275
0.98
0.00
2.9
3.1
1.64
1.69
mg/l
0.12
27
249
18
184
0.98
0.00
5.1
3.7
7.96
7.44
mmol/l
0.25
18
178
19
194
0.98
0.00
4.6
4.6
—
—
—
0
0
281
2808
1.00
0.00
4.5
3.8
0.01
0.01
estimate
0.01
71
690
7
69
1.01
0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
1.1
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.1
—
395.43
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.04
—
0
6
6
59
1.02
-0.00
2.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
105.80
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.3
1.2
—
—
—
0
0
5
51
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
463.00
—
0
5
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
13.0
—
0.46
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint G6_ALCODEGEN and mortality.

Females

Parameter HR [95% CI] p-value
G6_ALCODEGEN 7.086 [6.16, 8.15] < 0.001
Birth year 0.994 [0.99, 1.0] 0.159

During the follow-up period (1.1.1998 — 31.12.2019), 1024 out of 2337 females with G6_ALCODEGEN died.

Males

Parameter HR [95% CI] p-value
G6_ALCODEGEN 5.864 [5.32, 6.46] < 0.001
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 4483 out of 8289 males with G6_ALCODEGEN died.

Mortality risk

Mortality risk for people of age

years, who have G6_ALCODEGEN.

N-year risk Females Males
1 0.797% 1.179%
5 3.618% 6.351%
10 9.524% 14.645%
15 18.008% 27.105%
20 29.468% 41.761%

Relationships between endpoints

↥

Index endpoint: G6_ALCODEGEN – Degeneration of the brain due to alcohol

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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