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Other specified/unspecified deforming dorsopathies

EFO MESH Endpoint Browser PheWeb

M13_DEFORMDORSONAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M43.8, M43.9
  • Hospital discharge: ICD-9 — 732[8-9]|737[8-9]
  • Hospital discharge: ICD-8 — 735
  • Cause of death: ICD-10 — M43.8, M43.9
  • Cause of death: ICD-9 — 732[8-9]|737[8-9]
  • Cause of death: ICD-8 — 735

2 out of 7 registries used, show all original rules.

789

4. Check minimum number of events

None

789

5. Include endpoints

None

789

6. Filter based on genotype QC (FinnGen only)

712

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6805 4430 2315
Only index persons 5608 3751 1857
Unadjusted period prevalence (%)
Whole population 0.11 0.13 0.06
Only index persons 0.12 0.14 0.07
Median age at first event (years)
Whole population 27.44 27.05 27.44
Only index persons 20.06 19.14 21.92

-FinnGen-

Key figures

All Female Male
Number of individuals 712 517 195
Unadjusted period prevalence (%) 0.16 0.18 0.09
Median age at first event (years) 21.37 17.22 32.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
734
Matched controls
7340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
73599
ICD-8 Finland
Other and unspecified curvature of spine
+∞
307.7
339
*
9102
FHL
Trepanation or removal of the local bone process
82.1
162.9
87
12
M48.0
ICD-10 Finland
Spinal stenosis
34.7
133.5
86
28
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
18.9
132.1
109
67
M43.9
ICD-10 Finland
Deforming dorsopathy, unspecified
+∞
101.5
95
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
15.9
99.7
89
63
M43.1
ICD-10 Finland
Spondylolisthesis
27.6
88.4
61
24
7328A
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[JALKATERÄN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
85.1
80
*
7328B
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[MUIDEN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
82.9
78
*
N03AX12
ATC
[U] gabapentin; oral
5.6
70.6
156
338
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
12.9
66.1
66
56
M41.9
ICD-10 Finland
Scoliosis, unspecified
92.1
61.1
67
8
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
112.7
57.8
62
6
N03AX16
ATC
[U] pregabalin
3.9
51.9
186
582
M54.4
ICD-10 Finland
Lumbago with sciatica
4.4
49.1
141
374
7373A
ICD-9 Finland
Curvature of spine, Kyphoscoliosis and scoliosis
+∞
44.2
42
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
9.7
43.5
52
57
M54.5
ICD-10 Finland
Low back pain
3.0
43.2
278
1234
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.5
41.6
114
290
M41.2
ICD-10 Finland
Other idiopathic scoliosis
216.8
40.3
41
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
114.0
40.2
43
*
N06AX21
ATC
duloxetine; oral
4.1
40.1
126
355
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
+∞
40.0
38
*
M43.8
ICD-10 Finland
Other specified deforming dorsopathies
408.3
39.5
39
*
N02AX02
ATC
tramadol; systemic, rectal
2.8
39.4
330
1669
9103
FHL
Partial or complete bone removal
105.6
37.1
40
*
7378X
ICD-9 Finland
Curvature of spine, Other curvatures of spine
+∞
34.7
33
*
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
13.9
34.1
32
24
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
178.0
33.0
34
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.1
32.6
59
104
M54.9
ICD-10 Finland
Dorsalgia, unspecified
4.1
31.9
97
265
M43.0
ICD-10 Finland
Spondylolysis
89.1
31.0
34
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
35.3
29.0
37
11
M47.9
ICD-10 Finland
Spondylosis, unspecified
44.4
27.9
34
8
L03
ICPC
Low back symptom/complaint
2.6
27.3
217
1035
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
27.3
26
*
M54.1
ICD-10 Finland
Radiculopathy
10.7
25.5
28
27
7328X
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[OSTEOCHONDROPATHIAE ALIA DEFINITA]
+∞
25.1
24
*
N02BF01
ATC
gabapentin; oral
3.7
24.4
84
249
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
123.9
22.7
24
*
M54.6
ICD-10 Finland
Pain in thoracic spine
4.1
22.6
66
174
N02AC04
ATC
dextropropoxyphene; oral
7.2
21.8
33
48
SPAT1229
SPAT
Assessment of need for aid
4.0
21.6
65
175
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
21.1
284
1667
M47.82
ICD-10 Finland
Other spondylosis, cervical region
17.5
20.6
32
19
71798
ICD-8 Finland
Other nonarticular rheumatism, Other muscular rheumatism, fibrositis and myalgia
75.6
19.8
22
*
M54.3
ICD-10 Finland
Sciatica
5.3
18.5
38
75
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
7.7
18.3
26
35
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
17.8
17
*
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
+∞
17.8
17
*
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
184.3
17.6
18
*
L28
ICPC
Limited function/disability (L)
2.4
17.2
136
634
M01AB55
ATC
diclofenac, combinations; oral
3.8
17.1
55
155
R07.3
ICD-10 Finland
Other chest pain
2.9
17.0
88
333
M41
ICD-10 Finland
Scoliosis
26.3
17.0
23
9
M41.8
ICD-10 Finland
Other forms of scoliosis
36.0
16.7
21
6
72898
ICD-8 Finland
Vertebrogenic pain syndrome, Alia definita
+∞
16.7
16
*
7329X
ICD-9 Finland
Osteochondropathies, Unspecified osteochondropathy
+∞
16.7
16
*
M54.8
ICD-10 Finland
Other dorsalgia
5.4
16.7
33
63
L86
ICPC
Back syndrome with radiating pain
4.2
16.4
45
113
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.4
16.2
41
97
M50.3
ICD-10 Finland
Other cervical disc degeneration
19.0
16.1
24
13
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
19.0
16.1
24
13
N02BF02
ATC
pregabalin; oral
3.6
16.1
55
162
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
16.1
189
1036
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
15.8
115
516
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.8
15.6
85
330
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
14.1
15.6
26
19
M79.6
ICD-10 Finland
Pain in limb
1.9
15.6
321
2135
M03BX01
ATC
baclofen; systemic
6.6
15.5
25
39
R52.2
ICD-10 Finland
Other chronic pain
4.6
15.3
37
84
N06AA09
ATC
amitriptyline; systemic
3.1
15.2
67
231
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.2
15.2
26
43
M03BX02
ATC
tizanidine; oral
1.9
15.1
460
3451
M01AH02
ATC
rofecoxib; oral
2.7
14.8
88
357
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
14.6
14
*
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
14.6
14
*
J01MA02
ATC
ciprofloxacin; systemic
1.9
14.4
270
1730
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.6
13.9
87
362
1220
FHL
Arthroscopy
4.0
13.7
39
101
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
13.6
13
*
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
13.6
13
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
13.5
292
1949
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
40.9
13.2
16
*
R06.0
ICD-10 Finland
Dyspnoea
2.0
13.1
188
1098
N05BA04
ATC
oxazepam; oral
1.9
13.0
198
1180
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
11.8
12.9
23
20
9359
FHL
Other measure in this category
+∞
12.5
12
*
72800
ICD-8 Finland
Vertebrogenic pain syndrome, Cervicalgia
+∞
12.5
12
*
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
12.5
12
*
M41.5
ICD-10 Finland
Other secondary scoliosis
+∞
12.5
12
*
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
132.2
12.5
13
*
M41.3
ICD-10 Finland
Thoracogenic scoliosis
132.2
12.5
13
*
A02BC05
ATC
esomeprazole; systemic
1.8
12.5
289
1958
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.7
12.5
29
64
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
12.3
287
1945
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
12.3
138
736
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
10.8
12.3
23
22
N06AX16
ATC
venlafaxine; oral
2.2
12.1
116
583
A02BC01
ATC
omeprazole; systemic
1.9
12.0
183
1086
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.1
12.0
25
50
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
12.0
11.9
21
18
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
11.8
184
1100
M54.2
ICD-10 Finland
Cervicalgia
3.1
11.8
50
169
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
11.7
249
1637
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
11.7
160
915
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
5.8
11.5
21
37
R1250
NOMESCO Finland
Evaluation of functional capability
4.9
11.5
25
52
M79.7
ICD-10 Finland
Fibromyalgia
4.2
11.5
31
77
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
11.5
11
*
73500, ,
ICD-8 Finland
+∞
11.5
11
*
A02BC03
ATC
lansoprazole; oral
1.9
11.4
193
1184
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
10.9
190
1173
H02AB06
ATC
prednisolone; systemic
1.7
10.9
325
2339
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
10.8
73
315
R52.1
ICD-10 Finland
Chronic intractable pain
28.5
10.8
14
5
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
21.8
10.7
15
7
N05CF01
ATC
zopiclone; oral
1.8
10.7
228
1494
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.9
10.7
172
1036
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
10.6
54
202
71310
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis cervicalis
+∞
10.4
10
*
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
10.4
10
*
9193
FHL
Spondylodesis (also includes correction)
+∞
10.4
10
*
N02AA05
ATC
oxycodone; systemic
2.1
10.4
111
579
A02BC02
ATC
pantoprazole; systemic
1.7
10.4
476
3817
N03AX09
ATC
lamotrigine; oral
3.2
10.4
42
138
M01AH05
ATC
etoricoxib; oral
1.7
10.3
443
3489
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
10.8
10.3
19
18
M01AX17
ATC
nimesulide; oral
1.9
10.2
153
899
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
10.2
57
224
M01AE51
ATC
ibuprofen, combinations; systemic
11.5
10.1
18
16
N06AX11
ATC
mirtazapine; oral
1.7
10.1
241
1626
P03
ICPC
Feeling depressed
2.3
10.1
77
351
M01AH01
ATC
celecoxib; oral
2.0
9.9
113
605
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
9.9
102
526
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.9
9.9
29
77
R52.9
ICD-10 Finland
Pain, unspecified
2.3
9.6
72
326
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
101.3
9.4
10
*
R51.80
ICD-10 Finland
Headache
2.0
9.4
112
608
71312
ICD-8 Finland
Osteo-arthritis and allied conditions, Spondylarthritis lumbalis sive lumbosacralis
+∞
9.4
9
*
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
9.4
9
*
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
+∞
9.4
9
*
72850
ICD-8 Finland
Vertebrogenic pain syndrome, Pain in thoracic spine
+∞
9.4
9
*
N06AB04
ATC
citalopram; systemic
1.8
9.3
151
907
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
9.3
185
1181
L02
ICPC
Back symptom/complaint
2.3
9.3
76
357
N03AE01
ATC
clonazepam; systemic
2.9
9.2
42
148
SPAT1301
SPAT
No procedures
1.7
9.2
186
1194
UJF32
NOMESCO Finland
Coloscopy
1.8
9.0
160
988
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
18.9
9.0
13
7
L17
ICPC
Foot/toe symptom/complaint
1.7
8.8
206
1375
ZZH31
NOMESCO Finland
Bone allograft, small pieces
14.2
8.7
14
10
NF1AA
NOMESCO Finland
Hip X-ray examination
2.5
8.7
53
218
J01DA01
ATC
[U] cefalexin
1.6
8.7
438
3524
M54
ICD-10 Finland
Dorsalgia
2.1
8.6
84
423
M01AB05
ATC
diclofenac; systemic, rectal
1.6
8.6
455
3698
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.9
8.6
25
66
A01
ICPC
Pain general/multiple sites
2.3
8.5
66
303
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
8.5
61
271
R03AC02
ATC
salbutamol; inhalant
1.6
8.5
392
3083
SPAT1263
SPAT
Sampling
1.6
8.5
267
1919
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
91.1
8.4
9
*
L29
ICPC
Musculoskeletal sympt/complt other
2.3
8.4
65
298
SPAT1260
SPAT
Consultation of another employee
1.9
8.4
111
624
M70.6
ICD-10 Finland
Trochanteric bursitis
2.1
8.4
87
449
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
8.3
8
*
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
+∞
8.3
8
*
SPAT1240
SPAT
Therapeutic discussion
2.2
8.3
76
373
N02BE01
ATC
paracetamol; systemic, rectal
1.9
8.3
630
5596
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.1
8.3
35
118
A02BA02
ATC
ranitidine; systemic
1.8
8.3
126
741
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
8.3
68
320
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.4
8.1
29
88
L01
ICPC
Neck symptom/complaint
1.9
8.1
109
615
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.1
8.1
33
109
N05AH04
ATC
quetiapine; oral
1.8
8.0
123
724
R4110, ,
SPAT
2.0
8.0
89
471
AA1AD
NOMESCO Finland
CT of head and brain
1.7
7.9
175
1146
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.1
7.8
79
404
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
7.8
138
850
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.8
7.7
133
811
WX725
NOMESCO Finland
Noninvasive ventilation
2.7
7.6
42
164
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
7.6
64
304
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.7
7.6
39
147
75618
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Maleformationes columnae vertebralis aliae
25.3
7.6
10
*
A02BA04
ATC
nizatidine; systemic
2.4
7.6
51
220
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.7
7.6
41
159
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
7.6
171
1125
M02AA07
ATC
piroxicam; topical
1.6
7.6
226
1595
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.7
7.5
167
1093
M25.5
ICD-10 Finland
Pain in joint
1.6
7.5
232
1649
S18
ICPC
Laceration/cut
1.6
7.5
294
2208
NAG42
NOMESCO Finland
Posterior fusion of cervical spine with or without fixation
80.9
7.4
8
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.6
7.4
41
161
M01AC06
ATC
meloxicam; systemic, rectal
1.6
7.4
232
1656
J01FA01
ATC
erythromycin; systemic
1.9
7.4
97
544
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
11.0
7.3
13
12
FN1AD
NOMESCO Finland
CT of coronary arteries
4.2
7.3
19
46
9211
FHL
Exploration or removal of diskusprolapse
+∞
7.3
7
*
J01FA06
ATC
roxithromycin; oral
1.6
7.2
272
2019
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.1
7.2
72
367
A06AD11
ATC
lactulose; oral
1.9
7.2
88
482
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
7.1
90
498
J96.1
ICD-10 Finland
Chronic respiratory failure
4.4
7.0
17
39
H02BX01
ATC
methylprednisolone, combinations; systemic
3.0
7.0
31
108
L13
ICPC
Hip symptom/complaint
1.8
6.9
116
701
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.5
6.9
44
185
R35
ICD-10 Finland
Polyuria
2.5
6.9
42
173
J01EA01
ATC
trimethoprim; systemic
1.6
6.9
183
1252
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.9
6.8
32
115
UKC02
NOMESCO Finland
Cystoscopy
1.9
6.8
82
446
R03BA01
ATC
beclometasone; inhalant
1.9
6.8
94
535
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
6.8
45
193
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
40.4
6.8
8
*
L85
ICPC
Acquired deformity of spine
40.4
6.8
8
*
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
22.7
6.7
9
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.3
6.6
51
234
B01AB05
ATC
enoxaparin; parenteral
1.6
6.6
197
1385
K07.60
ICD-10 Finland
Snapping jaw
2.4
6.5
42
178
WZA90
NOMESCO Finland
Other medical or dental certificate
1.7
6.5
149
981
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
6.5
76
410
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.5
112
683
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
3.5
6.5
22
65
K59.09
ICD-10 Finland
Constipation, unspecified
2.5
6.5
39
160
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
6.5
100
590
R20.2
ICD-10 Finland
Paraesthesia of skin
2.3
6.4
46
204
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
6.4
126
796
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
18.2
6.3
9
5
7210A
ICD-9 Finland
Spondylosis and allied disorders, Cervical spondylosis without myelopathy
+∞
6.3
6
*
72820
ICD-8 Finland
Vertebrogenic pain syndrome, Diffuse syndrome cerviocobrachial
+∞
6.3
6
*
7233A
ICD-9 Finland
Other disorders of cervical region, Cervicobrachial syndrome (diffuse)
+∞
6.3
6
*
G99.2*M47.9
ICD-10 Finland
Myelopathy in spondylosis
+∞
6.3
6
*
72899
ICD-8 Finland
Vertebrogenic pain syndrome, Other and unspecified
+∞
6.3
6
*
M47.8
ICD-10 Finland
Other spondylosis
+∞
6.3
6
*
M41.4
ICD-10 Finland
Neuromuscular scoliosis
+∞
6.3
6
*
9191
FHL
Correction equipment installation
+∞
6.3
6
*
G55.1
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders
26.9
6.2
8
*
NA2AD
NOMESCO Finland
Thoracic spine CT examination
26.9
6.2
8
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.2
188
1322
N06AB03
ATC
fluoxetine; oral
1.9
6.2
82
460
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.9
6.2
79
438
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
6.1
156
1052
N30.0
ICD-10 Finland
Acute cystitis
1.7
6.1
116
725
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.8
6.1
30
111
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.3
6.1
43
190
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.7
6.1
31
117
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.0
142
939
S01.50
ICD-10 Finland
Open wound in oral cavity
10.1
6.0
11
11
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.5
6.0
20
58
P29
ICPC
Psychological sympt/compl other
2.1
6.0
56
277
S20.2
ICD-10 Finland
Contusion of thorax
2.6
6.0
35
141

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
270
1769
1.83
13.18
2.7
2.4
56.87
66.00
u/l
0.95
254
1657
341
2441
1.74
12.01
15.0
11.9
1.24
1.20
inr
0.54
275
2015
140
768
2.02
11.53
2.5
1.9
—
—
—
0
0
336
2435
1.70
11.03
7.3
6.1
1.21
1.22
mmol/l
0.95
311
2250
227
1477
1.78
10.96
3.5
3.2
829.98
1212.41
ng/l
1.17
185
1244
403
3080
1.68
10.72
7.0
6.5
10.65
11.24
umol/l
0.50
389
2937
248
1667
1.74
10.62
2.9
2.1
174.50
235.28
u/l
0.54
235
1575
240
1620
1.72
10.02
4.4
3.8
7.40
7.40
ph
0.14
181
1138
171
1055
1.81
9.72
1.4
1.3
17.16
11.39
u/ml
0.41
68
424
459
3723
1.62
8.89
6.1
3.9
12.80
2173.48
e6/l
—
5
64
364
2806
1.59
8.63
8.1
6.8
1.21
1.22
mmol/l
1.20
307
2415
537
4564
1.66
8.28
9.7
7.7
77.10
77.90
u/l
0.23
523
4345
178
1164
1.70
8.10
1.5
1.3
37.88
30.37
iu/ml
0.33
64
357
55
243
2.37
7.74
4.6
7.3
—
—
—
0
0
205
1406
1.64
7.73
4.8
4.2
—
—
—
0
0
229
1624
1.60
7.49
3.9
2.8
—
—
—
0
0
106
615
1.85
7.23
1.8
1.6
—
—
—
0
0
262
1936
1.55
7.09
8.9
6.1
—
—
—
0
0
401
3246
1.52
7.09
6.1
4.5
6.48
6.66
mmol/l
1.14
383
3079
151
984
1.67
6.87
4.2
3.2
249.99
385.89
ng/l
0.45
107
690
323
2514
1.51
6.79
5.4
4.6
36.05
36.14
g/l
0.10
296
2372
333
2611
1.50
6.74
2.8
2.6
—
—
estimate
—
0
0
206
1456
1.58
6.72
3.6
2.8
0.29
0.43
e6/l
0.83
153
1039
39
157
2.57
6.71
1.3
1.3
249.21
293.28
ug/g
0.73
19
91
385
3115
1.50
6.66
5.0
3.4
16.25
4.88
estimate
0.30
85
647
352
2800
1.49
6.59
2.8
2.4
77.43
76.70
nmol/l
0.18
318
2585
387
3139
1.49
6.58
4.9
3.4
0.11
0.51
estimate
0.37
79
606
381
3095
1.48
6.34
5.0
3.3
0.03
0.00
estimate
0.73
80
635
137
891
1.66
6.24
1.6
1.3
469.63
526.80
titre
0.19
27
200
202
1443
1.55
6.23
1.5
1.3
3.49
1.42
u/ml
0.62
57
402
81
455
1.88
6.11
2.2
3.0
10.37
10.82
g/l
0.40
71
424
223
1645
1.51
5.88
5.5
3.4
0.00
0.01
estimate
0.96
78
602
179
1261
1.55
5.83
1.6
1.5
2.11
2.31
g/l
0.86
114
828
167
1164
1.56
5.69
3.1
2.5
5.67
7.01
e6/l
0.55
152
1064
304
2402
1.45
5.62
5.0
3.3
0.04
0.03
estimate
0.10
67
514
44
204
2.23
5.59
1.1
1.0
—
—
—
0
0
229
1715
1.49
5.56
3.9
2.9
38.10
95.53
e6/l
0.73
175
1283
269
2082
1.46
5.52
4.1
3.2
20.38
56.38
ng/l
1.27
181
1338
370
3047
1.43
5.40
8.1
6.3
0.04
0.04
e9/l
0.47
327
2652
376
3106
1.43
5.39
8.3
6.2
1.92
1.93
e9/l
0.03
336
2773
173
1233
1.53
5.29
1.6
1.7
451.01
41707044.31
pmol/l
1.69
147
1043
369
3050
1.42
5.21
8.0
6.2
0.56
0.56
e9/l
0.06
325
2650
201
1486
1.49
5.14
3.2
2.5
323.44
331.53
umol/l
0.52
176
1350
149
1036
1.55
5.09
3.3
2.5
509.07
523.07
mosm/kgh2o
0.31
128
909
237
1813
1.45
5.09
2.4
2.2
—
—
—
0
0
179
1298
1.50
5.02
5.1
3.3
1.02
1.02
kg/l
1.41
111
845
262
2047
1.44
5.01
3.7
3.4
2.35
2.36
mmol/l
0.84
241
1902
119
788
1.61
5.00
2.8
2.3
25.25
23.08
%
0.97
110
732
308
2478
1.42
5.00
4.4
3.0
6.22
6.18
ph
0.30
183
1467
378
3157
1.41
4.93
8.4
6.5
0.18
0.18
e9/l
0.09
336
2779
116
768
1.61
4.88
2.6
2.4
94.33
105.32
ug/g
0.22
100
622
206
1549
1.46
4.79
1.7
1.6
20.42
20.26
nmol/l
0.06
172
1326
649
6028
1.66
4.66
19.5
12.9
22.39
22.65
mg/l
0.07
550
4844
127
868
1.56
4.66
2.7
2.3
2.40
2.33
g/l
0.87
117
804
86
535
1.69
4.61
10.3
9.0
5.15
5.08
kpa
0.29
81
521
402
3416
1.39
4.61
11.6
10.0
4.11
3.98
e9/l
0.51
357
2984
181
1337
1.47
4.59
1.7
1.7
1.03
1.09
mg/l
0.11
134
1019
258
2042
1.41
4.48
4.9
3.4
68.33
113.09
e6/l
0.83
189
1383
85
536
1.66
4.34
10.3
9.1
7.43
7.42
ph
0.33
50
305
12
24
5.06
4.33
2.8
1.8
—
—
—
0
0
347
2899
1.37
4.31
8.4
6.3
27.71
28.07
%
0.24
333
2772
48
257
1.93
4.23
2.0
2.1
2.29
8.62
iu/ml
1.78
16
63
98
647
1.59
4.17
1.8
1.6
—
—
—
0
0
106
714
1.57
4.14
6.2
5.6
1.05
1.02
mmol/l
0.46
95
664
84
537
1.64
4.07
10.3
9.0
1.70
1.11
mmol/l
0.99
72
443
341
2859
1.36
4.06
8.2
6.2
57.49
57.14
%
0.21
329
2746
7
7
10.08
4.01
1.6
3.1
—
—
—
0
0
336
2822
1.35
3.91
8.5
6.4
8.65
8.71
%
0.17
318
2666
213
1666
1.39
3.87
1.4
1.4
—
—
—
0
0
68
417
1.70
3.86
10.8
8.3
—
—
—
0
0
114
793
1.52
3.85
1.3
1.2
—
—
—
0
0
263
2133
1.36
3.82
3.8
3.2
30.70
31.45
u/l
0.16
248
2029
657
6178
1.60
3.79
20.9
14.7
139.72
139.72
mmol/l
0.00
649
6054
99
670
1.55
3.79
2.6
2.6
9.22
7.20
umol/l
0.34
82
580
32
154
2.13
3.78
1.2
1.1
—
—
—
0
0
82
532
1.61
3.75
2.0
2.2
0.21
0.22
g/l
0.70
74
509
236
1886
1.37
3.75
3.1
3.4
7.19
7.57
mmol/l
0.66
198
1614
335
2826
1.34
3.73
8.5
6.3
0.69
0.69
%
0.04
317
2655
333
2819
1.33
3.58
8.5
6.3
2.82
2.83
%
0.02
314
2663
184
1424
1.39
3.53
2.6
2.2
2.79
2.90
mg/l
0.28
161
1230
174
1335
1.40
3.51
2.2
2.2
—
—
—
0
0
294
2456
1.33
3.42
2.3
2.0
99.62
98.15
pmol/l
0.18
152
1311
129
943
1.45
3.40
2.9
2.3
14.27
13.38
umol/l
0.85
120
877
78
513
1.58
3.39
3.7
3.0
7.37
7.38
ph
0.85
46
298
129
944
1.44
3.38
4.7
3.4
0.84
0.82
mmol/l
0.88
123
902
79
524
1.57
3.31
2.5
2.0
63.12
41.88
u/l
0.31
68
444
112
801
1.47
3.31
3.3
2.6
2.59
3.58
e6/l
0.50
48
373
60
372
1.67
3.30
1.5
1.8
1.12
1.43
g/l
0.86
55
351
656
6201
1.54
3.30
21.2
14.8
3.95
3.95
mmol/l
0.09
649
6057
36
192
1.92
3.26
2.2
2.0
1208.68
3761.87
u/l
0.51
12
71
224
1810
1.34
3.24
4.4
2.9
0.04
0.07
estimate
0.12
67
488
33
172
1.96
3.19
1.6
1.3
3.60
12.11
u/ml
—
8
29
74
495
1.55
3.00
3.6
2.9
2.73
1.78
mmol/l
1.39
67
413
33
176
1.92
3.00
2.4
4.0
24.43
25.13
mmol/l
1.12
27
165
27
134
2.05
2.99
1.8
1.5
17644.95
16213.69
e6/l
0.08
22
97
64
415
1.59
2.97
3.2
3.5
77.97
76.39
ng/l
0.08
56
356
614
5760
1.40
2.91
6.5
5.3
1.86
1.87
mu/l
0.05
569
5401
32
173
1.89
2.81
1.3
1.2
—
—
—
0
0
14
53
2.67
2.80
1.4
2.2
3.97
8.35
umol/l
—
7
37
51
324
1.62
2.60
1.3
1.2
—
—
—
0
0
17
74
2.33
2.59
1.6
1.6
—
—
—
0
0
17
74
2.33
2.59
1.6
1.6
—
—
—
0
0
17
74
2.33
2.59
1.6
1.6
—
—
—
0
0
17
74
2.33
2.59
1.6
1.6
—
—
—
0
0
531
4905
1.30
2.57
5.4
4.4
14.64
14.56
pmol/l
0.31
494
4585
42
256
1.68
2.51
2.2
2.3
—
—
—
0
0
9
26
3.49
2.48
2.3
1.6
5.62
7.01
u/l
—
9
21
14
57
2.48
2.46
1.2
1.4
—
—
—
0
0
55
361
1.57
2.46
4.0
3.0
—
—
—
0
0
11
38
2.92
2.42
2.9
2.3
46.83
42.73
%
—
6
18
50
323
1.59
2.39
2.4
3.7
7.40
7.42
ph
1.29
43
274
20
97
2.09
2.39
1.6
1.2
—
—
—
0
0
137
1074
1.34
2.38
3.1
2.7
2.44
2.45
mmol/l
0.26
127
980
60
405
1.52
2.38
2.5
2.4
25.52
18.64
au/ml
—
5
50
228
1916
1.28
2.37
4.0
3.2
—
0.80
—
0
5
71
498
1.47
2.34
4.3
4.8
0.45
0.66
%
0.35
22
152
77
549
1.45
2.34
3.3
4.6
14.00
15.98
ug/l
0.06
56
433
20
98
2.07
2.33
1.2
1.9
0.49
0.90
g/l
1.27
14
75
11
40
2.78
2.28
1.1
1.0
—
—
—
0
0
112
857
1.36
2.28
1.7
1.6
—
—
—
0
0
177
1447
1.29
2.27
4.4
3.6
89.78
93.50
%
1.11
171
1419
97
726
1.39
2.26
1.7
1.4
—
—
—
0
0
62
431
1.48
2.16
1.3
1.3
64.71
212.25
u/ml
3.17
57
399
71
507
1.44
2.15
5.0
5.2
0.43
0.83
%
0.23
20
127
7
19
3.71
2.15
1.9
2.0
—
—
—
0
0
6
14
4.31
2.15
1.2
1.2
94.50
87.71
nmol/24h
—
6
14
342
3037
1.24
2.15
3.5
2.9
101.37
107.86
ug/l
0.27
322
2868
71
508
1.44
2.13
4.8
4.9
0.05
0.15
%
0.90
20
143
28
161
1.77
2.08
2.6
2.5
—
—
—
0
0
208
1755
1.26
2.06
3.2
3.5
22.28
44.36
mg/l
2.75
118
1109
77
564
1.41
2.04
2.4
3.1
1.66
1.82
%
0.90
66
511
63
446
1.45
2.01
3.7
3.5
1.22
1.23
mmol/l
0.61
53
378
62
440
1.45
1.96
1.7
1.5
—
—
—
0
0
73
534
1.41
1.96
4.8
4.8
0.50
1.10
%
1.95
22
168
37
236
1.60
1.91
1.1
1.6
—
20.04
—
0
5
55
385
1.46
1.87
2.3
2.2
34.09
7.53
ug/l
0.88
47
339
63
454
1.42
1.85
10.6
7.7
8.73
9.01
mmol/l
0.13
63
435
21
115
1.85
1.84
1.1
1.1
—
—
—
0
0
68
500
1.40
1.79
1.2
1.2
101.05
146.42
u/ml
0.61
22
215
108
857
1.31
1.74
2.0
1.7
1217.01
1166.07
nmol/l
0.23
82
648
73
547
1.37
1.72
2.1
2.0
352.09
388.03
nmol/l
0.57
64
517
5
13
3.86
1.71
4.4
3.4
—
—
—
0
0
5
13
3.86
1.71
1.4
1.2
49.44
45.27
g/l
—
5
7
676
6557
1.39
1.64
23.4
16.5
71.93
73.18
umol/l
0.76
671
6482
32
206
1.58
1.62
1.7
1.9
1.68
1.49
g/l
0.42
26
179
5
14
3.59
1.62
1.0
1.1
—
—
—
0
0
19
106
1.81
1.60
1.9
1.5
—
—
—
0
0
32
207
1.57
1.59
1.2
1.3
—
—
—
0
0
16
85
1.90
1.56
1.2
2.0
—
—
—
0
0
22
130
1.71
1.54
1.5
1.9
122.24
130.75
g/l
0.72
17
111
8
33
2.44
1.54
2.9
2.1
585.38
450.74
e6/l
—
8
27
208
1807
1.21
1.53
4.0
4.2
3.30
7.87
mg/mmol
4.00
121
1114
5
15
3.35
1.52
1.0
1.0
—
—
—
0
0
24
146
1.67
1.52
2.7
3.2
3.58
2.69
ratio
0.14
14
84
202
1751
1.21
1.52
8.2
6.0
—
—
—
0
0
50
682
0.71
1.52
1.5
1.8
3.42
3.48
mmol/l
0.14
36
490
671
6512
1.35
1.51
14.0
10.7
26.76
25.61
u/l
0.43
660
6359
25
155
1.63
1.48
2.8
3.6
25.08
46.37
mg/l
0.59
20
133
25
155
1.63
1.48
2.8
3.6
40.44
86.24
mg/l
0.59
20
133
616
5917
1.26
1.48
5.2
4.6
5.78
5.85
mmol/l
0.80
574
5486
171
1463
1.22
1.46
4.9
4.6
—
—
—
0
0
14
73
1.94
1.44
13.6
7.0
10.84
11.04
mg/l
0.05
14
66
25
157
1.61
1.42
2.6
2.7
—
—
—
0
0
61
461
1.35
1.40
5.2
3.3
—
—
—
0
0
7
29
2.43
1.39
1.1
1.4
131.57
141.69
nmol/l
—
7
29
265
2940
0.85
1.39
3.0
3.0
—
—
—
0
0
12
60
2.02
1.38
1.4
1.5
33.26
22.95
ng/l
0.49
12
60
9
41
2.21
1.37
1.3
1.1
—
—
—
0
0
34
233
1.48
1.34
2.6
3.8
—
—
—
0
0
13
68
1.93
1.34
1.6
2.6
—
—
—
0
0
125
1047
1.23
1.31
2.2
1.7
—
—
—
0
0
30
202
1.51
1.29
2.3
3.8
1161.45
1677.41
u/ml
0.14
22
176
15
84
1.80
1.28
2.6
2.8
—
—
—
0
0
54
408
1.35
1.26
2.5
3.1
66.59
67.30
g/l
0.26
47
387
19
115
1.67
1.26
1.3
1.2
263.09
302.38
u/ml
0.35
11
64
6
25
2.41
1.24
1.5
1.2
118.50
176.24
mmol/24h
—
6
25
13
70
1.87
1.24
1.1
1.5
—
0.58
nmol/l
—
0
5
64
499
1.31
1.21
2.3
2.0
0.00
0.05
estimate
0.78
15
101
543
5185
1.18
1.20
22.9
16.3
13.62
13.55
%
0.70
537
5116
655
6367
1.27
1.20
17.1
12.0
—
—
—
0
0
296
2701
1.16
1.19
13.9
10.4
0.00
0.00
e9/l
1.31
248
2233
16
94
1.72
1.18
1.0
1.1
—
—
—
0
0
285
2596
1.16
1.17
2.2
2.1
—
—
—
0
0
25
166
1.52
1.16
1.6
1.5
—
—
—
0
0
45
337
1.36
1.13
2.3
2.5
—
—
—
0
0
54
418
1.32
1.09
2.0
3.3
69.14
71.39
e9/l
0.21
40
313
5
21
2.39
1.09
1.0
1.1
—
48.14
—
0
7
19
121
1.59
1.06
1.8
2.9
7.69
8.22
kpa
0.85
19
121
471
4470
1.15
1.04
3.7
3.1
40.86
45.01
u/l
0.81
446
4252
9
46
1.97
1.04
2.4
1.5
1.37
1.08
promille
—
9
36
9
46
1.97
1.04
1.3
1.2
—
—
—
0
0
25
171
1.48
1.03
1.3
1.2
—
1121.25
—
0
8
18
114
1.59
1.03
1.5
1.4
—
—
—
0
0
11
61
1.82
0.99
1.1
1.5
—
—
nmol/l
—
0
0
27
190
1.44
0.98
4.3
3.7
86.75
298.32
mg/l
2.02
12
85
17
108
1.59
0.97
3.5
3.5
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
—
—
—
0
0
17
110
1.56
0.91
1.4
1.7
—
—
—
0
0
19
127
1.51
0.89
1.5
1.8
—
—
—
0
0
12
71
1.70
0.89
1.0
1.2
—
—
—
0
0
8
42
1.91
0.88
1.3
1.1
—
—
—
0
0
57
461
1.26
0.86
2.6
2.4
6.11
6.06
ph
0.14
33
281
8
44
1.83
0.86
1.1
1.3
—
—
—
0
0
8
44
1.83
0.86
1.0
1.0
—
—
—
0
0
80
674
1.21
0.84
1.4
1.3
—
—
—
0
0
32
240
1.35
0.84
1.3
1.3
—
—
—
0
0
35
269
1.32
0.79
1.7
1.5
0.19
0.35
mg/l
2.51
20
131
8
48
1.67
0.79
1.4
1.3
10.44
11.10
umol/l
—
8
43
20
140
1.44
0.77
1.3
1.4
27.39
30.04
u/l
0.14
14
119
62
515
1.22
0.76
1.6
1.4
27.93
30.55
iu/l
0.24
54
452
87
747
1.19
0.76
2.8
3.4
3.99
4.15
e9/l
0.27
74
660
132
1173
1.15
0.75
5.7
4.7
3.31
2.32
ug/l
0.39
114
1066
12
75
1.61
0.75
1.8
1.3
15.78
36.83
mu/l
0.87
12
68
28
211
1.34
0.73
2.1
1.9
—
—
—
0
0
64
537
1.21
0.72
3.4
4.4
7.36
7.35
ph
0.06
39
388
7
41
1.71
0.70
1.0
1.1
—
—
—
0
0
12
181
0.66
0.70
1.0
1.0
—
—
—
0
0
59
493
1.21
0.69
1.3
1.2
—
—
—
0
0
9
59
1.53
0.68
1.3
1.5
281.00
283.77
mosm/kgh2o
—
9
43
7
43
1.63
0.67
2.1
2.7
—
—
—
0
0
77
663
1.18
0.67
1.6
1.6
—
—
—
0
0
5
28
1.79
0.66
1.6
4.3
16.30
16.43
%
—
5
28
20
146
1.38
0.64
1.2
1.1
—
—
—
0
0
20
146
1.38
0.64
1.2
1.1
—
—
—
0
0
5
29
1.73
0.64
1.6
1.0
199.40
161.78
iu/ml
—
5
29
8
49
1.64
0.62
1.0
1.1
—
—
—
0
0
94
829
1.15
0.61
1.3
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
2.5
—
33.65
—
0
16
22
166
1.34
0.59
2.3
3.6
3.82
2.11
index
0.31
11
91
8
53
1.51
0.58
1.4
2.0
—
—
—
0
0
8
54
1.49
0.57
3.9
3.6
55.25
53.61
%
—
8
49
22
167
1.33
0.57
2.2
2.0
—
—
—
0
0
6
36
1.67
0.56
1.3
1.2
3.67
9.25
mm/h
—
6
36
29
230
1.27
0.56
2.0
1.9
—
—
—
0
0
29
230
1.27
0.56
2.0
1.7
—
—
—
0
0
29
231
1.27
0.54
2.0
1.9
—
—
—
0
0
29
231
1.27
0.54
2.0
1.9
—
—
—
0
0
594
5812
1.12
0.54
6.4
5.7
38.84
38.84
mmol/mol
0.00
561
5488
9
60
1.51
0.54
1.3
1.3
—
—
—
0
0
6
38
1.58
0.54
1.7
3.6
862.67
1104.34
u/ml
—
6
38
21
160
1.32
0.54
7.4
7.1
—
—
—
0
0
9
61
1.48
0.54
1.0
1.3
—
—
—
0
0
11
74
1.49
0.53
1.6
2.3
—
—
—
0
0
9
62
1.46
0.53
2.7
2.6
—
41.46
—
0
7
6
40
1.50
0.51
2.2
2.6
656.17
1037.42
mg
—
6
40
683
6746
1.18
0.51
28.3
20.1
261.27
257.21
e9/l
0.90
674
6611
15
109
1.38
0.51
3.3
1.5
60.43
64.32
%
0.29
15
109
683
6748
1.17
0.49
28.4
20.2
6.68
6.66
e9/l
0.06
674
6589
683
6748
1.17
0.49
28.3
20.1
4.45
4.50
e12/l
1.96
674
6591
12
84
1.44
0.49
1.0
1.1
—
—
—
0
0
40
474
0.83
0.49
1.6
1.8
—
—
—
0
0
7
51
1.38
0.44
1.3
1.2
—
—
—
0
0
32
266
1.21
0.44
2.4
2.0
0.00
0.05
estimate
0.68
12
76
5
31
1.62
0.43
1.0
1.4
183.98
168.29
pmol/l
—
5
31
5
33
1.52
0.41
1.6
1.6
—
—
—
0
0
8
59
1.36
0.41
1.1
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
12.74
—
0
13
0
18
0.00
0.40
0.0
1.1
—
44.03
—
0
18
14
106
1.33
0.39
1.1
1.1
1.44
3.83
u/ml
—
9
41
30
355
0.84
0.38
1.2
1.2
0.88
0.91
g/l
0.34
30
355
5
36
1.39
0.38
1.4
1.1
—
—
—
0
0
9
69
1.31
0.37
2.0
2.1
—
—
—
0
0
79
719
1.11
0.36
3.4
2.8
0.64
0.80
ug/l
1.43
46
418
22
181
1.22
0.35
1.3
1.3
—
—
—
0
0
637
6290
1.10
0.34
5.7
5.3
2.77
2.83
mmol/l
0.92
595
5913
6
44
1.37
0.34
1.2
3.5
0.83
0.77
index
—
6
44
30
350
0.85
0.34
1.2
1.2
1.56
1.58
g/l
0.15
30
350
6
45
1.34
0.34
1.0
1.1
—
—
—
0
0
42
370
1.14
0.32
2.8
2.4
13.02
13.11
nmol/l
0.03
36
345
629
6213
1.09
0.32
5.1
4.8
4.70
4.79
mmol/l
1.35
591
5863
7
54
1.30
0.30
5.6
3.6
—
—
—
0
0
47
420
1.13
0.30
1.2
1.2
—
—
—
0
0
55
497
1.12
0.29
1.8
1.6
—
—
—
0
0
273
2639
1.05
0.27
2.0
1.9
1.35
1.37
mmol/l
0.19
232
2272
11
86
1.28
0.26
5.9
3.3
1.27
1.68
%
0.20
11
78
11
87
1.27
0.24
1.4
1.3
—
—
—
0
0
18
152
1.19
0.24
1.2
1.1
0.30
1.85
u/ml
—
9
71
626
6199
1.07
0.23
5.1
4.7
1.48
1.51
mmol/l
0.81
587
5819
5
38
1.32
0.23
2.2
1.9
2.38
4.62
mg/l
—
5
38
5
42
1.19
0.21
10.6
7.9
0.48
26.74
ug/l
—
5
28
0
11
0.00
0.21
0.0
4.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
14.40
—
0
5
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
5.3
—
—
—
0
0
8
103
0.77
0.21
1.4
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
9.42
—
0
13
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
3.8
—
46.91
—
0
8
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
3.7
2.8
—
—
—
0
0
6
52
1.16
0.19
1.3
1.1
427.17
467.57
nmol/l
—
6
44
41
378
1.09
0.17
1.1
1.1
—
—
—
0
0
13
110
1.19
0.17
1.2
1.6
—
—
—
0
0
52
555
0.93
0.16
1.5
1.4
—
—
—
0
0
16
140
1.15
0.15
5.3
4.3
—
—
—
0
0
11
93
1.19
0.14
3.8
2.9
3.54
4.32
e9/l
0.57
11
93
12
103
1.17
0.14
1.3
1.1
—
—
—
0
0
13
114
1.14
0.12
1.2
1.3
—
—
—
0
0
11
95
1.16
0.11
1.4
1.2
—
—
—
0
0
14
124
1.13
0.11
3.5
2.8
56.03
58.47
%
0.27
14
124
596
5927
1.03
0.09
4.3
4.0
1.26
1.28
mmol/l
0.22
558
5522
5
47
1.06
0.09
1.6
1.4
—
—
—
0
0
24
223
1.08
0.09
1.2
1.3
172.40
234.38
miu/ml
—
5
113
6
57
1.05
0.08
1.0
1.1
132.33
112.63
pmol/l
—
6
57
7
64
1.09
0.08
3.9
1.9
—
—
—
0
0
10
88
1.14
0.08
1.6
2.4
—
—
—
0
0
18
195
0.92
0.08
1.2
1.4
1086.15
1110.66
mu/l
0.05
13
145
82
797
1.03
0.07
1.4
1.4
—
—
—
0
0
6
73
0.82
0.07
1.0
1.1
—
—
—
0
0
7
81
0.86
0.07
1.1
1.1
—
—
—
0
0
11
122
0.90
0.07
1.7
1.8
175.73
210.70
pmol/l
0.57
11
115
42
406
1.04
0.05
3.0
2.5
119.65
52.67
u/ml
0.39
42
394
10
91
1.10
0.04
3.2
1.7
—
—
—
0
0
77
756
1.02
0.04
1.3
1.4
—
—
—
0
0
22
212
1.04
0.02
1.6
1.3
—
—
—
0
0
10
93
1.08
0.02
1.1
1.0
—
—
—
0
0
68
671
1.01
0.02
1.8
1.5
—
—
—
0
0
24
233
1.03
0.01
2.2
1.8
—
—
—
0
0
14
135
1.04
0.00
1.1
1.0
0.38
4.52
u/ml
—
5
62
13
127
1.02
0.00
2.5
2.3
29.61
120.05
ug/min
—
8
80
19
188
1.01
0.00
4.8
2.0
2.50
34.58
iu/l
—
9
80
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
81.53
—
0
6
6
63
0.95
-0.00
1.8
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
365.13
—
0
8
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
70
1.00
-0.00
1.1
2.8
32.71
32.49
pg
—
7
70
0
6
0.00
-0.00
0.0
2.2
—
321.00
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
1.84
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.52
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.03
—
0
5
0
5
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
15.98
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint M13_DEFORMDORSONAS and mortality.

Females

Parameter HR [95% CI] p-value
M13_DEFORMDORSONAS 1.568 [1.23, 2.0] < 0.001
Birth year 0.997 [0.99, 1.01] 0.519

During the follow-up period (1.1.1998 — 31.12.2019), 118 out of 546 females with M13_DEFORMDORSONAS died.

Males

Parameter HR [95% CI] p-value
M13_DEFORMDORSONAS 1.136 [0.78, 1.64] 0.5
Birth year 0.984 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 373 males with M13_DEFORMDORSONAS died.

Mortality risk

Mortality risk for people of age

years, who have M13_DEFORMDORSONAS.

N-year risk Females Males
1 0.184% 0.208%
5 1.08% 1.234%
10 2.375% 3.06%
15 4.839% 5.699%
20 8.709% 9.628%

Relationships between endpoints

↥

Index endpoint: M13_DEFORMDORSONAS – Other specified/unspecified deforming dorsopathies

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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