Infection of intervertebral disc (pyogenic)

M13_DISCINFECTION

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M46.3
  • Cause of death: ICD-10 M46.3

2 out of 7 registries used, show all original rules.

568

4. Check minimum number of events

None

568

5. Include endpoints

None

568

6. Filter based on genotype QC (FinnGen only)

511

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M46
Name in latin
Infectio disci intervertebralis (pyogenes)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2789 1003 1779
Only index persons 2627 945 1682
Unadjusted period prevalence (%)
Whole population 0.04 0.03 0.05
Only index persons 0.05 0.03 0.06
Median age at first event (years)
Whole population 64.58 68.10 62.60
Only index persons 64.18 67.66 62.22

-FinnGen-

Key figures

All Female Male
Number of individuals 511 164 347
Unadjusted period prevalence (%) 0.13 0.06 0.16
Median age at first event (years) 68.03 69.65 67.27

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
527
Matched controls
5270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
+∞
307.7
525
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
47.3
252.9
155
46
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
26.0
220.4
169
94
M48.0
ICD-10 Finland
Spinal stenosis
72.1
214.6
118
21
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
50.4
194.0
115
29
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
33.5
193.1
130
51
M46.4
ICD-10 Finland
Discitis, unspecified
+∞
171.5
155
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
236.4
154.0
152
9
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
35.3
147.7
96
33
M54.5
ICD-10 Finland
Low back pain
8.5
137.7
302
718
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.8
110.7
204
393
N03AX16
ATC
[U] pregabalin
7.6
109.0
210
423
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
57.4
107.2
61
12
J04AB02
ATC
rifampicin; systemic
34.4
94.3
61
20
M54.9
ICD-10 Finland
Dorsalgia, unspecified
9.8
90.6
118
150
N03AX12
ATC
[U] gabapentin; oral
7.5
84.6
145
253
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
8.3
82.6
126
193
N02AA05
ATC
oxycodone; systemic
5.6
81.6
231
646
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
7.2
80.9
146
268
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
238.6
80.8
81
*
N02AX02
ATC
tramadol; systemic, rectal
5.2
75.2
337
1348
M54.4
ICD-10 Finland
Lumbago with sciatica
7.4
74.3
125
212
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
33.5
70.8
46
15
A40.8
ICD-10 Finland
Other streptococcal sepsis
26.2
70.8
50
21
L03
ICPC
Low back symptom/complaint
5.1
70.4
215
630
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
23.0
69.8
52
25
J01FF01
ATC
clindamycin; systemic
4.8
69.8
258
878
A41.9
ICD-10 Finland
Sepsis, unspecified
10.1
69.6
85
98
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.8
66.1
225
713
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
23.4
63.7
47
22
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.9
61.9
109
192
A41.8
ICD-10 Finland
Other specified sepsis
14.5
58.8
55
42
N02BF01
ATC
gabapentin; oral
7.4
58.5
94
150
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
+∞
58.4
55
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.6
55.5
391
2029
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
21.6
55.3
42
21
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.3
54.5
203
674
TPH04
NOMESCO Finland
Cathetrisation of vein
4.2
53.5
211
729
N02BF02
ATC
pregabalin; oral
8.7
49.2
66
85
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.7
47.5
133
352
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.5
47.1
145
413
JN4AD
NOMESCO Finland
Body CT examination
4.4
47.0
151
444
R50.9
ICD-10 Finland
Fever, unspecified
4.3
46.9
154
460
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
134.7
46.6
49
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.5
46.3
142
403
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.5
46.2
71
107
ZXD05
NOMESCO Finland
Urgent procedure
3.6
45.9
244
1012
J01CF05
ATC
flucloxacillin; systemic
6.0
45.7
90
175
A46
ICD-10 Finland
Erysipelas
4.1
44.7
161
513
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.1
43.6
157
499
N06AX21
ATC
duloxetine; oral
5.6
40.4
85
175
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.2
40.2
56
75
J01MA12
ATC
levofloxacin; systemic
3.6
39.6
178
653
C03CA01
ATC
furosemide; systemic
3.3
39.6
268
1264
JN3AD
NOMESCO Finland
Abdominal CT examination
4.1
39.5
131
390
M46.2
ICD-10 Finland
Osteomyelitis of vertebra
+∞
39.0
37
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.5
39.0
189
726
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.5
38.4
67
115
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
88.8
37.4
41
5
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.3
36.8
111
307
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
35.8
196
806
L28
ICPC
Limited function/disability (L)
3.5
35.0
158
576
M54.8
ICD-10 Finland
Other dorsalgia
11.0
33.7
37
36
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
10.2
33.7
39
41
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
347.8
33.3
33
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.8
33.0
82
194
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
32.9
121
384
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
10.2
32.8
38
40
B01AB05
ATC
enoxaparin; parenteral
3.0
32.7
236
1125
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
32.6
31
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
8.9
32.5
42
51
A02BC02
ATC
pantoprazole; systemic
3.6
32.4
423
2790
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.1
32.3
104
300
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.3
32.0
49
73
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
8.8
31.6
41
50
J01CF02
ATC
cloxacillin; systemic
9.3
31.4
39
45
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
30.5
211
976
R4110
NOMESCO Finland
Physiotherapy
2.9
30.4
208
956
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
12.1
30.3
31
27
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
30.1
217
1024
J01MA02
ATC
ciprofloxacin; systemic
2.8
29.8
270
1434
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
8.2
29.3
40
52
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.1
29.0
89
247
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.2
28.8
52
92
M03BC01
ATC
orphenadrine (citrate); systemic
3.4
28.5
128
459
A28
ICPC
Limited function/disability NOS
3.1
28.3
159
651
TKC20
NOMESCO Finland
Catheterisation of bladder
4.3
27.8
79
207
SPAT1255
SPAT
Intravenous administration of medicine
4.5
27.8
73
180
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.3
27.4
77
200
AA1AD
NOMESCO Finland
CT of head and brain
2.7
27.0
226
1139
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
27.5
26.5
36
14
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
39.0
26.5
33
9
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
10.2
26.1
30
31
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
25.4
117
424
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
25.0
250
1363
J01DB01
ATC
cefalexin; oral
3.9
24.3
467
3509
Z49.1
ICD-10 Finland
Extracorporeal dialysis
10.1
24.3
28
29
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
27.0
24.3
33
13
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
24.1
23
*
L86
ICPC
Back syndrome with radiating pain
6.2
24.1
43
75
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
23.9
255
1425
TQW11
NOMESCO Finland
Vacuum treatment of wound
9.0
23.9
30
35
WX402
NOMESCO Finland
General anaesthesia
2.8
23.8
154
673
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
5.1
23.7
53
114
JN4BD
NOMESCO Finland
Extensive body CT
3.2
23.6
109
394
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.5
23.6
62
152
TK800
NOMESCO Finland
Hemodialysis
7.2
23.6
36
53
X59
ICD-10 Finland
Exposure to unspecified factor
2.9
23.6
138
572
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.6
23.5
193
951
Z3226
NOMESCO Finland
Physiotherapist
3.0
23.4
127
505
M54.3
ICD-10 Finland
Sciatica
7.1
23.2
36
54
A01
ICPC
Pain general/multiple sites
4.0
23.1
72
201
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
23.1
22
*
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
+∞
23.1
22
*
N06AA09
ATC
amitriptyline; systemic
4.3
22.7
62
157
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.2
22.6
65
171
S97
ICPC
Chronic ulcer skin
3.9
22.2
70
197
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
+∞
22.0
21
*
L17
ICPC
Foot/toe symptom/complaint
2.5
21.9
192
970
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
40.6
21.9
27
7
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.6
21.7
81
256
N02BE01
ATC
paracetamol; systemic, rectal
5.5
21.4
499
4019
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
35.5
21.3
27
8
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
21.2
245
1400
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
21.0
20
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
6.5
20.9
35
57
M03BX02
ATC
tizanidine; oral
2.4
20.8
312
1993
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.9
20.7
114
454
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.6
20.4
72
219
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.8
20.3
48
108
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.0
20.2
105
405
ZXD35
NOMESCO Finland
Usual procedure
5.9
19.9
37
67
H02AB06
ATC
prednisolone; systemic
2.3
19.8
282
1747
B18.2
ICD-10 Finland
Chronic viral hepatitis C
17.6
19.4
30
18
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.4
19.4
51
125
B03XA02
ATC
darbepoetin alfa; parenteral
6.3
19.3
33
55
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
21.0
19.3
28
14
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
19.1
98
374
M13.9
ICD-10 Finland
Arthritis, unspecified
3.9
19.1
60
168
WX704
NOMESCO Finland
Intubation
4.0
19.0
58
159
S18
ICPC
Laceration/cut
2.3
18.9
291
1851
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
7.2
18.4
28
41
R33
ICD-10 Finland
Retention of urine
3.1
18.2
83
296
M54
ICD-10 Finland
Dorsalgia
3.4
18.1
71
231
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.5
18.0
66
205
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.1
18.0
52
137
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
5.4
17.9
36
70
WX892
NOMESCO Finland
Monitored bed care
3.3
17.9
73
243
M46.5
ICD-10 Finland
Other infective spondylopathies
+∞
17.8
17
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.5
17.5
44
104
UJF32
NOMESCO Finland
Coloscopy
2.3
17.2
168
877
A11CC03
ATC
alfacalcidol; systemic
5.6
17.1
33
62
A06AD11
ATC
lactulose; oral
2.7
17.0
110
473
M54.2
ICD-10 Finland
Cervicalgia
4.5
17.0
43
102
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
17.0
183
994
R52.0
ICD-10 Finland
Acute pain
5.9
17.0
31
55
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.9
16.6
38
83
WX110
NOMESCO Finland
Infiltration anesthesia
2.3
16.5
381
2794
R60.0
ICD-10 Finland
Localized oedema
2.9
16.4
90
355
M79.6
ICD-10 Finland
Pain in limb
2.2
16.2
224
1340
R53
ICD-10 Finland
Malaise and fatigue
2.4
16.2
149
754
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
16.2
215
1266
R5110, ,
SPAT
3.3
16.2
66
219
C08CA01
ATC
amlodipine; oral
2.1
16.1
255
1607
N05CF01
ATC
zopiclone; oral
2.2
16.1
190
1068
N05AH04
ATC
quetiapine; oral
2.6
16.0
106
461
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
5.3
15.9
33
66
C07AB07
ATC
bisoprolol; oral
2.1
15.7
311
2127
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
15.7
15
*
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
15.7
15
*
J01XX08
ATC
linezolid; systemic
22.9
15.7
22
10
WX872
NOMESCO Finland
Intensive care
3.5
15.5
56
172
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
15.5
120
562
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
15.4
123
583
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.8
15.4
49
138
X58
ICD-10 Finland
Exposure to other specified factors
2.7
15.3
93
387
R52.2
ICD-10 Finland
Other chronic pain
6.3
15.3
26
43
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.5
15.2
55
169
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
14.5
15.2
25
18
A40.1
ICD-10 Finland
Sepsis due to streptococcus, group B
46.4
15.1
18
*
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
6.5
15.1
25
40
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
14.8
131
650
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.6
14.7
24
38
NAS20
NOMESCO Finland
Incision and debridement of infection of vertebra, unspecified
+∞
14.6
14
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
14.6
14
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
14.6
191
1110
NF1AA
NOMESCO Finland
Hip X-ray examination
3.0
14.6
70
256
I50.0
ICD-10 Finland
Congestive heart failure
3.0
14.5
70
257
M47.82
ICD-10 Finland
Other spondylosis, cervical region
17.6
14.4
22
13
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.1
14.4
66
235
Z3231
NOMESCO Finland
Registered nurse
2.2
14.4
169
941
A12AA04
ATC
calcium carbonate; oral
6.4
14.3
24
39
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
6.6
14.2
23
36
M54.1
ICD-10 Finland
Radiculopathy
15.0
14.2
23
16
A10AB05
ATC
insulin aspart; parenteral
3.1
14.1
65
232
M54.6
ICD-10 Finland
Pain in thoracic spine
4.5
14.0
35
82
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
13.2
14.0
24
19
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.0
14.0
41
109
P19
ICPC
Drug abuse
31.0
14.0
18
6
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.1
14.0
30
62
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
20.7
13.9
20
10
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.2
13.9
57
190
WX002
NOMESCO Finland
Sedation and analgesia
2.3
13.8
129
653
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
13.8
100
452
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
13.6
13
*
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
+∞
13.6
13
*
ZXA05
NOMESCO Finland
Left side
2.2
13.6
149
805
M25.5
ICD-10 Finland
Pain in joint
2.1
13.5
161
898
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.8
13.5
31
68
M43.1
ICD-10 Finland
Spondylolisthesis
18.8
13.5
20
11
TQW40
NOMESCO Finland
Remowal of suture of skin
3.3
13.5
53
172
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.2
13.4
37
94
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
13.4
97
438
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.0
13.2
29
61
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
13.2
274
1864
N03AE01
ATC
clonazepam; systemic
4.0
13.1
38
100
E66.9
ICD-10 Finland
Obesity, unspecified
5.4
13.1
26
50
L70
ICPC
Infection of musculoskeletal system
29.2
13.0
17
6
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
29.2
13.0
17
6
M47.9
ICD-10 Finland
Spondylosis, unspecified
29.2
13.0
17
6
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
13.0
110
532
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.6
13.0
31
70
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.1
12.7
55
189
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.0
12.7
61
223
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
71.6
12.6
14
*
N06AX11
ATC
mirtazapine; oral
2.0
12.6
181
1077
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
12.6
207
1292
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
10.4
12.6
24
24
NAW10
NOMESCO Finland
Reoperation for superficial infection in in surgery of spine or neck
+∞
12.5
12
*
NA3CM
NOMESCO Finland
Lumbar spine extensive MRI examination with 3 Tesla magnet
+∞
12.5
12
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.7
12.5
29
64
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
4.9
12.5
28
60
J01MA14
ATC
moxifloxacin; systemic
2.8
12.5
67
260
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
12.4
54
186
N05BA01
ATC
diazepam; systemic, rectal
2.6
12.4
79
335
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.7
12.3
41
119
M43.0
ICD-10 Finland
Spondylolysis
38.5
12.3
15
*
ZX120
NOMESCO Finland
Intravenous
2.8
12.2
65
251
S76
ICPC
Skin infection other
3.2
12.1
50
167
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
9.6
12.1
24
26
M04AA01
ATC
allopurinol; systemic
2.3
12.1
105
513
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
5.2
12.1
25
50
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
12.0
189
1158
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
12.0
196
1217
C03DA01
ATC
spironolactone; oral
2.4
11.9
93
433
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.4
11.9
30
71
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.4
11.9
89
407
WVA20
NOMESCO Finland
Medicine administration
4.6
11.8
28
63
ZXE00
NOMESCO Finland
One hour or less
1.9
11.7
211
1352
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.0
11.7
158
916
N06AX16
ATC
venlafaxine; oral
2.7
11.7
69
281
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
30.8
11.7
15
5
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
30.8
11.7
15
5
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
23.5
11.6
16
7
L04AA13
ATC
[U] leflunomide
10.4
11.6
22
22
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
10.4
11.6
22
22
XF600
NOMESCO Finland
Bloodpressure measurement
3.3
11.6
46
150
M01AH01
ATC
celecoxib; oral
2.4
11.5
91
426
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
+∞
11.5
11
*
9211
FHL
Exploration or removal of diskusprolapse
+∞
11.5
11
*
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
+∞
11.5
11
*
SPAT1229
SPAT
Assessment of need for aid
3.0
11.4
52
184
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.8
11.4
36
101
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.4
11.3
42
131
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.6
11.2
70
293
WX725
NOMESCO Finland
Noninvasive ventilation
3.5
11.2
40
122
SPAT1254
SPAT
Administration of medicine
2.3
11.2
93
445
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
11.1
150
867
S10
ICPC
Boil/carbuncle
3.3
11.1
44
143
SPAT1301
SPAT
No procedures
2.0
11.1
171
1036
WX720
NOMESCO Finland
Own respiration
3.7
11.1
36
103
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.4
10.9
41
129
N18.8
ICD-10 Finland
Other chronic renal failure
4.5
10.9
27
63
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
10.9
10.9
20
19
UKC02
NOMESCO Finland
Cystoscopy
2.1
10.8
114
600
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.0
10.8
163
978
A04
ICPC
Weakness/tiredness general
2.3
10.8
90
431
N05BA04
ATC
oxazepam; oral
2.0
10.7
138
783
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.1
10.7
30
77
V03AE01
ATC
polystyrene sulfonate; oral
8.2
10.7
23
29
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.6
10.7
65
269
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.7
10.7
34
96
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
4.5
10.6
26
60
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.9
10.6
51
186
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.5
10.6
37
111
R03AC02
ATC
salbutamol; inhalant
1.8
10.6
267
1889
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
10.5
112
592
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
10.5
125
689
WX199
NOMESCO Finland
Other local analgesia
3.7
10.5
34
97
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.6
10.5
35
102
WX702
NOMESCO Finland
Supraglottic ventilation device
3.4
10.5
38
117
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.6
10.5
20
37
XX1XW
NOMESCO Finland
Extensive written report from radiologist
5.6
10.5
20
37
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.2
10.4
42
138
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.3
10.4
41
133
ZXA10
NOMESCO Finland
Bilateral
2.1
10.4
110
580
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
10.4
365
2856
N30.0
ICD-10 Finland
Acute cystitis
2.3
10.3
82
384
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.5
10.3
69
299
M01AB05
ATC
diclofenac; systemic, rectal
1.8
10.3
326
2466
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
10.2
114
613
Z02.7
ICD-10 Finland
Issue of medical certificate
3.0
10.2
48
173
E66.8
ICD-10 Finland
Other obesity
3.9
10.2
30
80
ZXA00
NOMESCO Finland
Right side
1.9
10.1
151
901
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
4.9
10.1
22
46
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
10.3
10.1
19
19
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.9
10.0
48
175
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.3
10.0
85
410
WW500
NOMESCO Finland
Blood transfusion
3.3
9.9
38
121
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
9.9
60
247
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
9.9
52
199
E0000UV, ,
ATC
1.8
9.9
209
1393
Z2446
NOMESCO Finland
Social worker
2.9
9.8
47
171
A03
ICPC
Fever
2.2
9.7
85
415
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
56.0
9.7
11
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
56.0
9.7
11
*
N19
ICD-10 Finland
Unspecified kidney failure
3.3
9.7
37
118
L84
ICPC
Back syndrome without radiat pain
3.9
9.6
28
74
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
11.7
9.6
17
15
R06AE07
ATC
cetirizine; oral
1.8
9.6
195
1281
B01AB10
ATC
tinzaparin; parenteral
2.4
9.6
72
329
Z71.8
ICD-10 Finland
Other specified counselling
1.9
9.6
169
1063
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.0
9.5
27
70
A41.4
ICD-10 Finland
Sepsis due to anaerobes
101.8
9.4
10
*
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
30.6
9.4
12
*
U14
ICPC
Kidney symptom/complaint
5.3
9.4
19
37
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
+∞
9.4
9
*
M46.0
ICD-10 Finland
Spinal enthesopathy
+∞
9.4
9
*
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
9.4
9
*
E87.5
ICD-10 Finland
Hyperkalaemia
4.8
9.4
21
45
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
8.9
9.4
19
22
R4120
NOMESCO Finland
Occupational therapy
2.9
9.3
44
159
L02
ICPC
Back symptom/complaint
2.8
9.3
49
188
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
4.3
9.3
24
58
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.3
9.2
36
116
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
9.2
39
132
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
9.2
151
925
WW200
NOMESCO Finland
Immunization
4.4
9.2
23
54
N03AX09
ATC
lamotrigine; oral
4.4
9.2
23
54
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.1
9.2
40
138
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.9
9.2
27
72
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
9.2
106
576
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.1
9.1
95
496
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
9.3
9.1
18
20
Z49.0
ICD-10 Finland
Preparatory care for dialysis
10.3
9.1
17
17
R60.9
ICD-10 Finland
Oedema, unspecified
3.1
9.1
38
128
Z72.2
ICD-10 Finland
Drug use
37.4
9.0
11
*
SPAT1262
SPAT
Handing over of treatment supplies
2.0
9.0
111
616
SPAT1263
SPAT
Sampling
1.8
9.0
209
1422
D07AC01
ATC
betamethasone; topical
1.8
9.0
192
1276
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.2
9.0
35
113
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
8.9
57
241
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.9
8.9
44
163
207
Kela drug reimbursment
Chronic arrhythmias
2.0
8.9
114
642
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
8.8
138
831
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.2
8.8
35
114
N18.0
ICD-10 Finland
End-stage renal disease
9.7
8.8
17
18
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
3.5
8.8
30
89
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
7.8
8.7
19
25
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
50.8
8.7
10
*
B01AA03
ATC
warfarin; systemic
1.9
8.7
125
732
Z72.0
ICD-10 Finland
Tobacco use
4.5
8.7
21
48
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.3
8.7
33
105
M01AH02
ATC
rofecoxib; oral
2.4
8.6
64
290
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
8.4
8.6
18
22
WX882
NOMESCO Finland
High dependency care
3.9
8.6
25
66
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.2
8.6
23
57
B01AF02
ATC
apixaban; oral
2.1
8.6
96
514
D07AA02
ATC
hydrocortisone; topical
2.2
8.6
74
358
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.9
8.5
40
144
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.0
8.5
24
62
NB1AT
NOMESCO Finland
Puncture of shoulder with ultrasound guidance
20.4
8.5
12
6
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
20.4
8.5
12
6
Z2221
NOMESCO Finland
Medical doctor
1.9
8.5
145
897
SPAT1211
SPAT
Application of soft bandage
2.6
8.5
52
216
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
91.5
8.4
9
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
4.6
8.4
20
45
R06.0
ICD-10 Finland
Dyspnoea
1.8
8.4
150
940
NH1AD
NOMESCO Finland
Ankle and foot CT
5.0
8.4
18
37
R10.0
ICD-10 Finland
Acute abdomen
4.8
8.4
19
41
R5599
NOMESCO Finland
Other rehabilitation service
4.8
8.4
19
41
ZX121, ,
SPAT
+∞
8.4
8
*
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.4
8.3
30
92
WVA20, ,
SPAT
3.5
8.3
29
87
M70.6
ICD-10 Finland
Trochanteric bursitis
2.4
8.3
59
262
J01DA01
ATC
[U] cefalexin
1.7
8.3
303
2323
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.4
8.3
57
250
C09AA02
ATC
enalapril; systemic
1.9
8.2
126
752
R35
ICD-10 Finland
Polyuria
2.7
8.1
46
183
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
8.3
8.1
17
21
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
11.9
8.1
14
12
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
17.5
8.1
12
7
M45
ICD-10 Finland
Ankylosing spondylitis
33.9
8.1
10
*
L29
ICPC
Musculoskeletal sympt/complt other
2.6
8.1
47
190
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.2
8.1
21
51
S29
ICPC
Skin symptom/complaint other
1.9
8.0
112
649
M02AA07
ATC
piroxicam; topical
1.8
8.0
175
1164
S01.0
ICD-10 Finland
Open wound of scalp
2.4
7.9
56
248
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
7.9
95
521
L04AA06
ATC
mycophenolic acid; systemic
4.7
7.9
18
39
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.5
7.9
27
80
P03
ICPC
Feeling depressed
2.9
7.9
38
139
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
7.1
7.8
18
26
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.1
7.8
81
421
A02BC01
ATC
omeprazole; systemic
1.8
7.8
133
820
A10AE04
ATC
insulin glargine; parenteral
2.2
7.8
70
344
205
Kela drug reimbursment
Chronic hypertension
1.8
7.8
165
1086
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
3.4
7.8
28
86
ZZH40
NOMESCO Finland
Substitute of bone
15.3
7.7
12
8
P01AB01
ATC
metronidazole; oral, rectal
1.7
7.7
179
1208
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
4.1
7.7
21
53
M02AA10
ATC
ketoprofen; topical
2.1
7.7
80
417
A02BC05
ATC
esomeprazole; systemic
1.7
7.7
193
1331
N02AJ13
ATC
tramadol and paracetamol; systemic
6.9
7.6
18
27
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
8.2
7.6
16
20
W19
ICD-10 Finland
Unspecified fall
2.3
7.6
57
259
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.5
7.6
50
214
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.1
7.6
32
108
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.6
7.6
44
177
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.7
7.6
42
165
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.0
7.6
34
119
V03AE02
ATC
sevelamer; oral
18.7
7.6
11
6
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
18.7
7.6
11
6
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
18.7
7.6
11
6
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.2
7.6
65
313
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
12.1
7.6
13
11
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
25.4
7.6
10
*
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
25.4
7.6
10
*
A40.0
ICD-10 Finland
Sepsis due to streptococcus, group A
25.4
7.6
10
*
J01CA04
ATC
amoxicillin; systemic
1.8
7.6
398
3333
A07EC01
ATC
sulfasalazine; oral, rectal
2.7
7.6
40
154
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
7.5
95
530
N02AC04
ATC
dextropropoxyphene; oral
3.8
7.5
23
63
A10AE06
ATC
insulin degludec; parenteral
3.4
7.5
27
83
T89
ICPC
Diabetes insulin dependent
3.1
7.5
31
104
A10AE05
ATC
insulin detemir; parenteral
2.7
7.5
41
161
WX202
NOMESCO Finland
Supraclavicular plexus blockade
7.8
7.4
16
21
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
81.2
7.4
8
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.2
7.4
68
337
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.9
7.4
34
121
R02
ICPC
Shortness of breath/dyspnoea
2.1
7.4
76
394
Z50.1
ICD-10 Finland
Other physical therapy
3.0
7.4
33
116
P15
ICPC
Chronic alcohol abuse
3.6
7.3
24
69
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
7.0
7.3
17
25
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.2
7.3
19
46
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.9
7.3
34
122
NA3DM
NOMESCO Finland
Lumbar spine very extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
M60.0
ICD-10 Finland
Infective myositis
+∞
7.3
7
*
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
+∞
7.3
7
*
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
7.3
7
*
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
7.3
7
*
A10AC01
ATC
insulin (human); parenteral
2.4
7.3
53
238
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.6
7.3
42
169
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
7.3
146
943
R52.9
ICD-10 Finland
Pain, unspecified
2.4
7.3
52
232
NBG10
NOMESCO Finland
Acromioplastia
4.6
7.2
17
38
N05CD07
ATC
temazepam; oral
2.1
7.2
71
362
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
7.2
91
508
A07EC02
ATC
mesalazine; oral, rectal
3.1
7.2
30
101
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
7.2
115
694
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
30.5
7.2
9
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.4
7.2
51
227
WX212
NOMESCO Finland
Femoral plexus blockade
4.2
7.1
19
47
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.0
7.1
32
113
N30.9
ICD-10 Finland
Cystitis, unspecified
2.8
7.1
36
136
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.6
7.0
40
160
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.2
7.0
28
92
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.8
7.0
35
131
M01AH05
ATC
etoricoxib; oral
1.6
7.0
281
2173
SPAT1260
SPAT
Consultation of another employee
1.9
6.9
91
514
X57
ICD-10 Finland
Unspecified privation
4.1
6.9
19
48
U04
ICPC
Incontinence urine
2.7
6.9
37
143
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.4
6.9
24
72
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.1
6.9
69
354
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.4
6.9
46
199
L88
ICPC
Rheumatoid/seropositive arthritis
3.9
6.9
20
53
WX203
NOMESCO Finland
Infraclavicular plexus blockade
4.2
6.9
18
44
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.2
6.9
18
44
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.6
6.9
41
168
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
6.8
99
578
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.3
6.8
51
232
NHQ40
NOMESCO Finland
Amputation of toe
6.2
6.8
17
28
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
6.8
67
342
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
40.6
6.8
8
*
L13
ICPC
Hip symptom/complaint
1.9
6.8
92
526
C02AC05
ATC
moxonidine; oral
2.7
6.8
37
145
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
17.0
6.8
10
6
QD6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in foot
17.0
6.8
10
6
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
4.0
6.8
19
49
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
6.8
152
1011
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
6.7
179
1244
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.8
6.7
20
54
ZX120, ,
SPAT
6.6
6.7
16
25
A07AA09
ATC
vancomycin; oral
6.6
6.7
16
25
J02AC01
ATC
fluconazole; systemic
1.7
6.7
141
921
N05AH03
ATC
olanzapine; systemic
2.7
6.7
37
146
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
6.7
73
387
Z01.2
ICD-10 Finland
Dental examination
1.6
6.7
205
1478
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.0
6.6
71
373
D09
ICPC
Nausea
3.5
6.6
22
64
M01AE01
ATC
ibuprofen; systemic, rectal
1.9
6.6
439
3838
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.7
6.6
35
135
R13
ICD-10 Finland
Dysphagia
2.6
6.6
39
159
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.6
6.6
38
153
S21
ICPC
Skin texture symptom/complaint
2.0
6.6
80
440
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
6.6
113
695
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
10.2
6.6
12
12
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.2
6.6
12
12
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
10.2
6.6
12
12
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.0
6.5
28
96
D02AE01
ATC
carbamide; topical
2.6
6.5
38
154
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
3.3
6.5
24
75
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.6
6.5
21
60
U08
ICPC
Urinary retention
3.6
6.5
21
60
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.6
6.5
21
60
ZZA00
NOMESCO Finland
Split skin graft
3.5
6.5
22
65
M70.2
ICD-10 Finland
Olecranon bursitis
3.1
6.5
27
91
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
7.5
6.4
14
19
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
6.4
54
258
G83.4
ICD-10 Finland
Cauda equina syndrome
70.7
6.4
7
*
M01AC06
ATC
meloxicam; systemic, rectal
1.7
6.4
164
1126
NB1AD
NOMESCO Finland
Shoulder CT examination
6.7
6.4
15
23
M01AB51
ATC
indometacin, combinations; oral, rectal
5.3
6.4
18
35
R31
ICD-10 Finland
Unspecified haematuria
2.0
6.4
75
408
D05AX52
ATC
calcipotriol, combinations; topical
2.8
6.4
32
120
SPAT1252
SPAT
Overall medication plan or its review
2.4
6.4
43
187
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
8.3
6.4
13
16
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
6.3
21
61
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.6
6.3
17
31
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
3.4
6.3
22
66
ACC51
NOMESCO Finland
Release of median nerve
2.6
6.3
36
144
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
9.4
6.3
12
13
L04AB04
ATC
adalimumab; parenteral
9.4
6.3
12
13
N03AG01
ATC
valproic acid; systemic, rectal
2.8
6.3
31
115
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
6.3
6
*
G58.0
ICD-10 Finland
Intercostal neuropathy
+∞
6.3
6
*
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
6.3
6
*
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
6.3
6
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.2
6.3
14
20
A02BC03
ATC
lansoprazole; oral
1.7
6.2
136
894
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
27.0
6.2
8
*
M10.9
ICD-10 Finland
Gout, unspecified
2.2
6.2
52
248
F10.20
ICD-10 Finland
Alcohol dependence currently independent
5.1
6.2
18
36
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
3.6
6.2
20
57
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
6.2
144
963
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.5
6.2
21
62
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.3
6.2
48
222
K92.1
ICD-10 Finland
Melaena
2.5
6.2
38
158
WZC30
NOMESCO Finland
Teaching
1.8
6.2
93
549
K02.1
ICD-10 Finland
Caries of dentine
1.6
6.1
271
2117
R4190
NOMESCO Finland
Nutritional therapy
3.0
6.1
27
94
L01BA01
ATC
methotrexate; systemic
3.8
6.1
18
48
M10.0
ICD-10 Finland
Idiopathic gout
2.8
6.1
30
111
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.7
6.1
19
53
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.2
6.1
23
73
K29.7
ICD-10 Finland
Gastritis, unspecified
3.4
6.1
21
63
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
10.2
6.1
11
11
H02AB04
ATC
methylprednisolone; systemic
2.0
6.1
72
393
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.0
110
688

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
409
1432
9.29
123.08
13.1
4.4
—
—
—
0
0
239
678
5.62
83.31
3.7
2.0
—
—
—
0
0
415
2084
5.66
66.18
15.4
6.3
61.62
58.15
%
7.81
407
2007
413
2096
5.49
64.12
16.0
6.5
9.24
9.24
%
0.01
402
1981
412
2091
5.45
63.84
15.9
6.3
2.87
2.88
%
0.03
401
1981
415
2125
5.48
63.39
16.0
6.4
23.28
26.42
%
7.69
407
2035
428
2258
5.77
62.58
15.1
6.2
1.65
1.89
e9/l
2.49
387
1979
410
2095
5.31
62.35
16.1
6.4
0.63
0.67
%
0.87
402
1978
424
2230
5.61
61.96
15.2
6.2
0.04
0.04
e9/l
0.00
380
1909
423
2226
5.56
61.61
15.2
6.2
0.66
0.60
e9/l
3.22
377
1897
340
1529
4.45
60.99
14.9
6.0
—
—
—
0
0
426
2289
5.49
59.43
16.1
6.5
0.20
0.19
e9/l
0.09
389
1982
113
227
6.06
55.95
2.4
2.0
1.28
2.96
ug/l
0.67
102
204
393
2057
4.58
54.83
11.4
5.4
32.18
35.03
g/l
14.78
383
1928
202
672
4.25
54.02
12.5
6.3
1.12
1.04
mmol/l
2.92
191
623
221
787
4.11
53.69
4.7
2.5
2.11
2.23
g/l
2.01
210
728
172
510
4.52
53.64
7.8
3.7
7.37
7.38
ph
0.35
111
297
176
538
4.41
52.62
2.5
1.7
—
—
—
0
0
228
840
4.02
52.57
4.8
2.6
10.18
12.78
umol/l
6.24
218
782
167
494
4.48
52.09
8.3
3.7
1.42
1.95
mmol/l
0.76
154
407
211
742
4.07
51.91
4.6
2.6
19.27
23.02
%
2.62
203
690
432
2515
4.98
49.81
20.2
10.3
4.54
4.15
e9/l
3.22
390
2188
146
407
4.58
48.90
2.7
2.9
64.38
66.36
g/l
1.91
138
379
277
1209
3.72
48.81
3.6
2.2
2.93
2.96
mg/l
0.07
250
1031
160
482
4.33
48.34
16.0
7.4
13.52
10.58
mmol/l
3.97
155
453
126
331
4.69
45.25
2.0
2.4
—
—
—
0
0
282
1291
3.55
45.23
4.3
3.1
—
—
—
0
0
215
830
3.69
45.05
5.4
3.4
0.81
0.82
mmol/l
0.73
204
792
378
2091
3.86
44.67
13.6
6.8
1.20
1.21
mmol/l
1.02
362
1929
400
2312
4.03
43.84
17.7
7.6
1.20
1.21
mmol/l
1.44
362
1981
162
536
3.92
42.38
2.7
1.6
—
—
—
0
0
171
592
3.80
41.80
10.8
8.5
7.41
7.42
ph
0.20
80
339
170
590
3.78
41.35
10.6
8.5
5.17
5.09
kpa
0.37
163
579
170
590
3.78
41.35
10.6
8.5
12.11
11.98
kpa
0.12
162
579
393
2307
3.77
40.62
24.3
16.4
1.34
1.32
inr
0.24
348
1933
158
540
3.75
39.07
10.4
8.9
95.79
95.41
%
0.43
151
532
140
442
3.95
38.85
14.7
9.7
—
—
—
0
0
166
593
3.63
38.31
10.6
8.4
1.09
1.05
mmol/l
0.03
144
499
120
344
4.22
38.01
5.8
4.1
137.75
98.62
ng/l
1.52
110
292
344
1912
3.30
37.74
5.1
2.9
194.67
160.57
ug/l
1.14
319
1767
100
254
4.62
37.03
1.9
2.0
1.70
1.56
g/l
0.72
92
228
81
173
5.35
36.86
1.8
3.2
39.81
47.89
mg/l
0.30
68
153
183
716
3.38
36.33
11.1
7.6
104.11
104.22
mmol/l
0.09
183
716
297
1541
3.12
36.26
6.0
3.3
60.48
112.78
e6/l
0.57
245
1174
80
173
5.27
35.87
1.8
3.2
53.76
94.18
mg/l
0.61
69
150
276
1383
3.09
35.69
7.8
4.2
7.40
7.40
ph
0.63
213
988
424
2732
3.82
35.29
10.4
5.3
6.97
6.88
mmol/l
0.35
414
2623
288
1492
3.05
34.84
6.3
3.4
37.28
35.92
u/l
0.17
280
1417
263
1307
3.02
34.12
5.7
3.2
0.57
0.54
e6/l
0.12
208
959
270
1370
2.99
33.58
4.0
2.6
54.87
66.14
u/l
1.05
262
1276
193
813
3.17
33.45
2.5
2.0
30.52
29.58
s
1.36
188
792
139
479
3.58
33.43
3.2
2.3
0.19
0.20
g/l
0.60
125
444
346
2043
3.02
31.98
4.7
2.8
—
—
estimate
—
0
0
270
1406
2.89
31.43
2.9
2.1
364.40
303.32
u/l
0.13
256
1326
188
813
3.04
30.71
2.0
1.8
1221.16
1148.46
nmol/l
0.44
151
607
317
1811
2.88
30.70
4.8
3.2
6.14
6.16
ph
0.10
165
999
138
498
3.40
30.63
3.3
2.8
68.40
67.98
e9/l
0.05
95
365
222
1057
2.90
30.35
4.5
2.7
5.67
4.32
e6/l
0.97
208
960
304
1708
2.84
30.25
7.1
3.8
77.66
161.09
e6/l
1.05
245
1224
59
113
5.75
30.09
2.0
1.4
47213.15
22744.48
e6/l
0.47
40
77
242
1219
2.82
29.56
5.7
3.1
—
0.00
estimate
—
0
8
47
73
6.97
29.48
2.0
1.3
—
—
—
0
0
158
634
3.13
29.25
3.2
2.8
1.89
1.76
%
0.89
144
565
140
524
3.28
29.14
4.8
2.9
8.91
9.22
umol/l
0.07
126
471
467
3374
4.37
29.06
23.7
8.6
101.92
80.83
u/l
9.18
459
3187
69
161
4.78
28.09
1.7
2.9
1.76
2.93
ratio
1.05
39
95
361
2280
2.85
27.64
5.6
3.6
0.04
0.69
estimate
0.47
70
448
357
2246
2.83
27.46
5.5
3.6
0.00
0.00
estimate
-0.00
77
484
272
1496
2.69
27.38
5.2
2.5
—
—
—
0
0
359
2269
2.83
27.30
5.6
3.6
0.00
0.01
estimate
0.80
78
492
279
1560
2.68
27.07
4.0
3.3
2963.77
1587.00
ng/l
2.30
243
1369
232
1197
2.68
26.32
4.4
2.9
380.35
366.41
umol/l
0.88
215
1053
195
929
2.74
25.84
4.8
2.9
516.38
550.99
mosm/kgh2o
1.72
180
809
126
476
3.16
25.52
2.4
1.5
—
—
—
0
0
134
525
3.08
25.49
1.5
1.3
358.40
379.82
titre
0.06
25
109
222
1137
2.65
25.36
4.7
2.5
—
—
—
0
0
310
1878
2.58
24.71
3.8
2.3
75.99
77.21
nmol/l
0.34
284
1657
116
425
3.22
24.68
2.8
2.3
28.50
144.39
u/l
0.53
98
366
168
765
2.76
24.06
4.8
3.0
2.00
1.96
e6/l
0.03
90
391
115
438
3.08
22.77
2.2
1.6
—
—
—
0
0
102
362
3.25
22.76
1.9
2.7
12.43
11.20
g/l
1.31
96
334
53
118
4.88
22.72
1.3
1.6
—
—
—
0
0
131
550
2.84
21.66
1.7
1.4
—
—
—
0
0
187
938
2.54
21.65
5.4
3.9
590.57
499.52
ng/l
0.14
159
788
169
809
2.60
21.56
4.7
2.9
1.76
1.18
e6/l
0.69
95
434
233
1319
2.37
20.39
16.6
6.2
—
—
—
0
0
104
397
3.02
20.36
3.7
3.2
320.04
240.06
ng/l
0.67
99
369
85
288
3.33
20.35
1.5
1.8
1.41
1.80
g/l
0.54
79
265
34
58
6.20
19.40
5.9
3.6
—
—
—
0
0
304
1974
2.28
18.72
30.1
11.8
0.00
0.00
e9/l
0.53
246
1616
169
869
2.39
18.00
1.9
1.6
1.94
1.50
mg/l
0.60
150
698
316
2114
2.24
17.70
3.0
2.1
93.09
94.63
pmol/l
0.26
193
1136
36
73
5.22
17.13
2.0
1.4
56.93
55.25
mmol/l
0.09
28
61
37
77
5.09
17.10
1.9
1.5
30.86
30.19
g/l
0.10
31
71
78
279
3.11
16.95
1.8
1.5
—
—
—
0
0
82
303
3.02
16.84
5.5
4.9
—
—
—
0
0
232
1436
2.10
15.12
2.5
1.7
17.72
19.69
nmol/l
1.51
212
1188
32
66
5.10
14.93
2.4
2.4
1.81
1.88
g/24h
0.03
20
40
33
70
4.96
14.91
4.8
2.2
—
—
—
0
0
406
3120
2.31
14.73
4.3
3.8
15.00
14.97
pmol/l
0.07
367
2804
496
4217
4.00
14.40
61.4
16.6
35.52
28.25
mg/l
6.76
486
3498
28
54
5.42
14.05
1.9
1.4
—
—
—
0
0
24
40
6.24
13.97
4.0
2.9
—
—
—
0
0
24
40
6.24
13.97
1.6
1.4
81.86
69.81
%
0.87
14
32
31
66
4.93
13.94
1.8
1.4
6555.11
1470.07
e6/l
0.62
19
46
48
144
3.57
13.77
7.1
5.9
1.31
1.33
mmol/l
0.07
42
130
32
71
4.73
13.72
1.8
1.5
178.58
170.69
au/ml
—
5
18
36
89
4.27
13.50
5.9
2.4
—
—
—
0
0
114
560
2.32
13.01
1.4
1.2
22.86
14.04
u/ml
0.32
28
203
22
18
12.70
12.71
1.5
1.0
432.82
301.61
iu/ml
0.36
22
18
89
395
2.51
12.70
5.2
4.6
0.66
0.68
%
0.05
41
134
36
94
4.04
12.56
5.9
2.3
—
—
—
0
0
143
782
2.14
12.50
1.5
1.5
3.31
2.73
g/l
2.13
105
479
35
91
4.05
12.29
6.1
2.4
—
—
—
0
0
233
1532
1.93
12.07
5.5
3.9
2.33
2.35
mmol/l
1.53
219
1388
35
93
3.96
11.93
6.1
2.0
—
—
—
0
0
76
323
2.58
11.84
6.2
3.7
7.41
7.42
ph
0.52
65
272
35
94
3.92
11.76
6.2
2.3
—
—
—
0
0
32
81
4.14
11.64
2.0
1.4
—
—
—
0
0
19
14
14.03
11.53
1.9
1.4
—
—
—
0
0
104
517
2.26
11.44
5.5
3.3
4.71
4.25
e9/l
1.13
91
437
116
603
2.18
11.43
1.4
1.2
40.15
36.54
iu/ml
0.13
42
192
370
2872
1.97
11.23
6.9
3.2
85.34
59.27
u/l
3.30
357
2671
88
412
2.36
11.11
5.9
4.7
0.74
0.96
%
0.44
38
142
86
403
2.36
10.82
5.6
5.0
0.06
0.23
%
1.06
36
120
87
411
2.34
10.75
3.7
2.4
0.57
0.56
e6/l
0.02
87
393
88
421
2.31
10.55
2.4
2.3
6.81
8.37
ug/l
0.37
78
373
159
955
1.95
10.49
5.5
3.8
1.02
1.02
kg/l
0.04
124
640
260
1831
1.83
10.40
6.0
3.8
55.92
99.48
ng/l
0.55
230
1414
25
57
4.55
10.37
1.8
1.4
127452.57
23315.55
e6/l
0.42
14
31
38
119
3.36
10.20
4.3
2.4
62.52
62.81
%
0.02
38
119
31
85
3.81
10.12
1.5
1.2
—
—
—
0
0
82
388
2.32
10.07
2.8
2.2
0.05
0.04
estimate
0.06
19
71
83
396
2.30
9.99
5.9
4.7
0.12
0.13
%
0.06
33
126
242
1687
1.80
9.84
5.7
3.6
0.02
0.03
estimate
0.28
62
401
31
87
3.72
9.80
1.3
1.2
265.47
349.29
u/ml
0.68
19
41
25
60
4.32
9.74
1.8
1.4
—
—
—
0
0
29
81
3.73
9.23
1.1
1.0
—
—
—
0
0
36
117
3.23
9.12
1.2
1.2
—
—
—
0
0
28
77
3.78
9.11
1.2
1.1
—
—
—
0
0
20
28
7.38
8.81
1.5
2.2
—
—
—
0
0
23
56
4.25
8.80
1.5
2.0
—
—
—
0
0
103
565
2.02
8.64
4.4
4.8
11.99
28.86
ug/l
0.56
92
477
31
95
3.40
8.62
1.2
1.2
—
—
—
0
0
240
1717
1.73
8.57
5.2
3.6
6.42
7.84
mmol/l
5.92
209
1432
184
1224
1.77
8.47
5.3
3.2
0.00
0.08
estimate
0.60
56
356
44
168
2.77
8.43
1.5
1.3
—
—
—
0
0
451
3889
2.11
8.42
5.9
4.7
2.06
2.03
mu/l
0.16
422
3500
488
4356
2.63
8.21
41.8
15.3
—
—
—
0
0
18
39
4.74
7.93
1.7
1.2
16011.67
345478.78
e6/l
—
9
27
51
217
2.49
7.89
3.2
2.1
0.00
0.02
estimate
0.49
13
55
104
591
1.95
7.85
1.5
1.3
—
—
—
0
0
54
238
2.41
7.75
7.0
3.6
—
—
—
0
0
23
62
3.83
7.71
1.6
1.7
—
—
—
0
0
29
92
3.28
7.65
1.2
1.2
4.74
3.83
mmol/l
1.90
29
85
32
108
3.09
7.64
1.3
1.3
675.63
508.17
mg/l
1.02
32
102
20
50
4.12
7.41
1.2
1.1
—
—
—
0
0
29
95
3.17
7.27
1.6
1.3
41.75
263.32
e6/l
0.69
20
74
29
95
3.17
7.27
1.7
1.3
2.31
43.86
e6/l
0.64
16
72
28
90
3.23
7.24
1.1
1.1
—
—
—
0
0
31
107
3.02
7.13
3.9
4.4
—
—
—
0
0
380
3168
1.72
7.03
5.8
4.3
—
0.43
—
0
7
141
916
1.74
6.83
6.6
5.1
—
—
—
0
0
45
194
2.44
6.78
2.4
1.6
0.20
0.35
mg/l
2.14
26
99
45
194
2.44
6.78
1.4
1.2
—
—
—
0
0
25
79
3.27
6.65
7.6
3.4
15.53
10.35
pmol/l
0.69
25
79
13
15
8.85
6.58
1.5
1.5
—
—
—
0
0
179
1254
1.65
6.49
6.0
3.7
0.00
0.01
estimate
0.96
63
434
31
114
2.83
6.39
2.5
2.5
124.22
129.10
g/l
0.40
23
95
494
4520
2.48
6.32
31.2
12.2
27.58
26.84
u/l
0.35
489
4370
12
13
9.41
6.31
3.7
2.9
0.64
0.61
mmol/l
0.27
12
13
136
892
1.71
6.31
4.1
3.3
2.48
2.46
mmol/l
0.87
121
805
102
616
1.81
6.30
1.3
1.4
—
—
—
0
0
29
104
2.89
6.26
4.2
4.3
3.53
2.54
mmol/l
0.90
22
66
226
1703
1.57
5.93
6.0
4.4
27.76
8.69
mg/mmol
2.04
165
1114
12
15
8.16
5.86
1.2
1.5
133.17
92.56
umol/l
—
6
9
48
231
2.19
5.64
3.1
2.8
—
—
—
0
0
25
88
2.93
5.59
1.6
1.3
—
—
—
0
0
148
1022
1.62
5.55
2.3
1.8
444.06
49520800.57
pmol/l
1.45
131
834
219
1661
1.54
5.47
4.9
3.7
123.90
51.99
mg/l
1.74
166
1120
13
22
6.03
5.25
1.6
1.2
—
—
—
0
0
44
211
2.18
5.22
2.5
1.6
—
—
—
0
0
396
3439
1.61
5.22
67.3
21.7
328.79
332.65
g/l
13.92
396
3422
32
134
2.48
5.16
5.2
3.1
2.45
1.80
index
0.31
20
76
37
169
2.28
4.94
2.0
1.7
—
—
—
0
0
14
29
4.93
4.84
1.8
1.3
19.94
29.10
%
—
9
21
25
96
2.68
4.80
1.7
1.9
—
—
—
0
0
17
52
3.34
4.78
1.1
1.1
—
—
—
0
0
38
183
2.16
4.48
6.2
3.5
254.64
245.00
mg/l
0.06
28
81
27
113
2.46
4.38
1.6
1.4
220.43
255.28
ug/g
0.23
12
70
80
502
1.70
4.28
1.6
1.4
—
—
—
0
0
12
25
4.89
4.20
1.0
1.0
—
—
—
0
0
21
80
2.69
4.11
2.6
2.2
—
—
—
0
0
119
835
1.55
4.04
1.4
1.2
1.05
0.95
u/ml
0.16
28
214
40
210
1.98
3.79
2.4
2.6
—
—
—
0
0
7
8
8.85
3.78
19.1
9.1
4.80
6.24
mmol/l
—
7
8
48
271
1.85
3.68
1.2
1.2
—
—
—
0
0
60
363
1.74
3.66
8.8
3.7
1.23
1.22
mmol/l
0.44
60
303
7
9
7.86
3.57
4.6
1.8
—
—
—
0
0
14
46
3.10
3.55
1.9
1.2
—
—
—
0
0
8
13
6.23
3.51
1.4
1.8
—
—
—
0
0
8
13
6.23
3.51
4.8
5.5
—
—
—
0
0
12
31
3.94
3.51
1.6
1.2
7.37
7.41
ph
—
6
22
13
42
3.15
3.39
1.2
1.1
—
—
—
0
0
13
38
3.48
3.33
2.0
3.1
44.17
40.63
%
—
6
20
14
48
2.97
3.32
1.6
1.6
34.96
48.90
ng/l
0.24
14
48
6
7
8.65
3.27
1.8
1.9
128.17
140.29
nmol/24h
—
6
7
9
19
4.80
3.25
3.2
1.6
126.56
65.37
ug/l
—
9
19
11
303
0.35
3.24
1.7
1.4
—
—
—
0
0
11
29
3.85
3.20
1.0
1.0
—
—
—
0
0
208
1690
1.38
3.18
2.6
2.3
—
—
—
0
0
9
20
4.56
3.12
1.9
2.4
—
—
—
0
0
128
1658
0.70
3.09
4.0
3.3
—
—
—
0
0
6
8
7.57
3.06
1.5
1.5
—
—
—
0
0
8
16
5.06
3.06
1.5
1.8
—
—
—
0
0
159
1246
1.40
2.99
1.4
1.4
—
—
—
0
0
5
5
10.08
2.98
8.4
10.8
42.20
34.80
ug/min
—
5
5
447
4156
1.50
2.81
9.1
6.9
41.65
40.22
mmol/mol
2.09
425
3857
11
279
0.38
2.74
1.6
1.7
2.60
3.49
mmol/l
—
6
201
13
48
2.75
2.73
4.3
2.2
0.31
0.21
mmol/l
0.03
13
48
6
10
6.05
2.70
1.3
1.7
—
—
—
0
0
13
49
2.69
2.64
2.4
1.3
—
—
—
0
0
14
55
2.59
2.63
1.2
1.1
—
—
—
0
0
17
74
2.34
2.60
1.2
1.5
—
—
—
0
0
17
74
2.34
2.60
1.2
1.5
—
—
—
0
0
17
74
2.34
2.60
1.2
1.5
—
—
—
0
0
17
74
2.34
2.60
1.2
1.5
—
—
—
0
0
218
1827
1.33
2.60
2.2
1.9
1.43
1.34
mmol/l
0.96
186
1484
5
7
7.20
2.55
1.6
2.9
0.40
1.29
%
—
5
7
203
1694
1.32
2.46
6.1
3.8
—
1.00
—
0
5
10
32
3.17
2.44
1.1
1.2
—
—
—
0
0
13
53
2.49
2.29
4.2
3.6
58.00
53.30
%
0.28
13
45
8
23
3.52
2.27
1.3
3.1
1250.38
1908.57
u/ml
—
8
23
6
13
4.65
2.27
1.2
1.2
—
—
—
0
0
6
13
4.65
2.27
3.7
1.5
8.22
20.62
mu/l
—
6
13
6
13
4.65
2.27
1.0
1.1
—
—
—
0
0
6
13
4.65
2.27
1.0
1.0
—
—
—
0
0
5
9
5.60
2.22
81.2
5.4
8.58
4.98
kpa
—
5
9
49
323
1.57
2.21
6.4
3.1
—
—
—
0
0
9
30
3.03
2.15
1.1
1.1
—
—
—
0
0
11
42
2.65
2.15
1.2
1.3
—
—
—
0
0
10
36
2.81
2.14
4.0
2.7
0.70
0.94
index
—
10
36
8
25
3.23
2.10
1.3
1.1
132.75
128.48
nmol/l
—
8
25
13
56
2.35
2.06
1.2
1.6
10.00
9.97
%
0.01
13
56
13
56
2.35
2.06
1.1
1.2
—
—
—
0
0
7
20
3.53
2.06
1.0
1.1
—
—
—
0
0
447
4214
1.40
2.06
6.3
5.3
6.32
6.10
mmol/l
1.94
408
3805
16
76
2.14
2.04
5.1
2.8
4.27
4.46
e9/l
0.15
16
76
65
464
1.46
2.03
1.7
1.5
—
—
—
0
0
34
210
1.66
2.00
1.4
1.3
217.02
225.80
u/ml
0.04
34
195
61
432
1.47
1.99
3.6
2.4
158.93
126.43
ug/g
0.28
54
336
19
100
1.93
1.88
1.4
1.1
—
—
—
0
0
11
46
2.42
1.86
1.3
1.4
—
—
nmol/l
—
0
0
459
4363
1.40
1.86
6.8
6.0
2.37
2.60
mmol/l
6.46
432
3991
6
17
3.56
1.84
1.7
1.1
—
—
—
0
0
19
101
1.91
1.83
6.8
2.8
60.58
58.28
%
0.43
19
101
449
4257
1.37
1.81
5.8
5.1
1.34
1.40
mmol/l
2.04
422
3886
432
4077
1.33
1.75
5.1
4.4
1.35
1.30
mmol/l
0.71
400
3698
5
13
3.87
1.72
3.4
3.7
6.40
7.53
ug/l
—
5
13
6
19
3.18
1.66
2.7
1.7
11.52
13.14
umol/l
—
6
14
6
19
3.18
1.66
1.7
1.3
29.50
9.11
mm/h
—
6
19
38
255
1.53
1.63
1.2
1.2
—
—
—
0
0
258
2305
1.23
1.62
5.8
5.4
1.87
2.58
ug/l
2.34
229
2059
31
199
1.59
1.61
1.2
1.2
—
—
—
0
0
61
452
1.40
1.59
10.8
4.4
7.36
7.36
ph
0.18
55
323
23
139
1.68
1.51
3.4
2.6
44.96
179.23
u/ml
0.83
23
132
449
4286
1.32
1.48
6.1
5.2
4.23
4.45
mmol/l
4.42
426
3947
10
45
2.25
1.47
1.2
1.2
—
—
—
0
0
7
28
2.52
1.45
1.0
1.4
—
—
—
0
0
6
22
2.75
1.44
1.3
1.2
16.33
12.79
g/l
—
6
15
10
46
2.20
1.40
1.7
2.5
448.90
1043.02
mg
—
10
46
7
29
2.43
1.39
2.1
2.0
0.67
0.49
e9/l
—
7
29
16
90
1.80
1.34
2.1
1.7
5.26
76.16
iu/l
—
7
32
8
34
2.37
1.29
1.9
1.8
34.10
31.32
%
—
8
34
8
35
2.31
1.27
1.1
1.1
102.87
104.83
pmol/l
—
8
35
25
163
1.56
1.25
2.4
1.8
48.12
38.76
nmol/l
1.67
25
157
21
132
1.62
1.22
2.2
1.7
167.14
222.49
pmol/l
1.78
21
124
5
19
2.65
1.22
1.6
1.0
106.20
190.21
mmol/24h
—
5
19
8
38
2.12
1.19
1.1
1.1
—
—
—
0
0
5
20
2.51
1.15
2.0
1.3
—
—
—
0
0
8
40
2.02
1.12
1.5
1.3
—
—
—
0
0
8
40
2.02
1.12
2.8
3.5
16.41
16.96
%
—
8
40
8
41
1.97
1.09
2.4
3.2
7.00
8.05
mmol/l
—
8
41
10
52
1.94
1.06
1.1
1.3
—
—
—
0
0
5
22
2.28
1.03
2.6
1.4
79.40
81.69
%
—
5
16
54
425
1.30
1.01
1.5
1.5
—
—
—
0
0
46
355
1.32
0.99
7.8
3.8
—
—
—
0
0
20
132
1.54
0.98
6.5
4.1
—
—
—
0
0
0
31
0.00
0.96
0.0
6.8
—
19.94
—
0
9
6
27
2.24
0.93
1.8
1.4
1.30
1.12
nmol/l
—
6
18
6
29
2.08
0.89
1.0
1.0
—
—
—
0
0
10
56
1.80
0.88
4.1
4.2
—
—
—
0
0
6
31
1.95
0.84
3.3
1.5
225.00
77.41
ng/l
—
6
31
5
24
2.09
0.74
1.0
1.3
15.40
18.87
nmol/l
—
5
19
6
110
0.54
0.72
1.2
1.7
—
—
—
0
0
9
57
1.59
0.71
1.1
1.1
—
—
—
0
0
9
57
1.59
0.71
1.1
1.1
—
—
—
0
0
5
26
1.93
0.71
1.0
1.0
1751.20
1345.31
miu/ml
—
5
26
5
26
1.93
0.71
1.8
1.7
—
—
—
0
0
18
128
1.42
0.66
3.3
2.4
216.62
90.49
ug/min
0.45
12
75
5
29
1.73
0.64
1.0
1.8
34.54
40.62
g/l
—
5
29
8
51
1.58
0.60
1.4
1.2
—
—
—
0
0
40
327
1.24
0.60
4.3
2.6
5.93
6.08
ph
0.54
27
229
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
119.91
—
0
17
6
35
1.72
0.58
1.3
3.7
6.92
7.46
mmol/l
—
6
23
8
124
0.64
0.55
1.3
1.5
—
—
—
0
0
58
499
1.18
0.54
2.8
2.3
12.96
13.43
nmol/l
0.16
49
455
6
39
1.54
0.53
1.2
1.4
—
—
—
0
0
10
69
1.46
0.44
5.3
2.8
17.90
22.81
u/ml
—
10
69
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
10.56
—
0
5
7
103
0.68
0.40
1.0
1.2
—
0.72
—
0
17
5
36
1.39
0.38
1.4
1.2
177.52
174.27
pmol/l
—
5
36
8
111
0.72
0.37
1.0
1.2
1.51
1.50
g/l
—
8
111
5
37
1.35
0.37
6.8
3.6
370.13
19.92
mg/l
—
5
31
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
10
75
1.34
0.30
1.6
2.5
—
—
—
0
0
23
196
1.18
0.27
1.2
1.2
276.00
148.89
u/ml
—
6
73
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
26.46
—
0
13
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
6
52
1.16
0.19
1.5
1.2
—
—
—
0
0
6
52
1.16
0.19
1.2
1.2
—
—
—
0
0
11
132
0.83
0.18
7.5
9.4
—
—
—
0
0
17
195
0.87
0.18
1.1
1.1
—
—
—
0
0
8
68
1.18
0.16
1.4
1.4
—
—
—
0
0
17
150
1.14
0.14
1.1
1.2
—
—
—
0
0
28
260
1.08
0.11
1.3
1.4
—
—
—
0
0
5
46
1.09
0.09
2.2
2.2
—
—
—
0
0
142
1390
1.03
0.09
3.2
3.2
0.71
0.80
ug/l
0.58
100
925
8
77
1.04
0.07
1.0
1.3
—
—
—
0
0
38
394
0.96
0.05
1.4
1.4
—
—
—
0
0
11
117
0.94
0.01
1.7
1.2
0.92
0.91
g/l
0.04
11
117
12
126
0.95
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
5.7
—
9.44
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.40
—
0
5
0
9
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
45.07
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
44.80
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
402.00
—
0
5
0
6
0.00
-0.00
0.0
6.0
—
9.67
—
0
6
0
6
0.00
-0.00
0.0
3.0
—
35.00
—
0
6

Mortality – FinRegistry

Association

Association between endpoint M13_DISCINFECTION and mortality.

Females

Parameter HR [95% CI] p-value
M13_DISCINFECTION 2.197 [1.72, 2.81] < 0.001
Birth year 0.991 [0.98, 1.0] 0.048

During the follow-up period (1.1.1998 — 31.12.2019), 208 out of 774 females with M13_DISCINFECTION died.

Males

Parameter HR [95% CI] p-value
M13_DISCINFECTION 2.163 [1.73, 2.7] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 430 out of 1413 males with M13_DISCINFECTION died.

Mortality risk

Mortality risk for people of age

years, who have M13_DISCINFECTION.

N-year risk Females Males
1 0.152% 0.427%
5 1.139% 2.451%
10 2.617% 5.546%
15 5.3% 10.663%
20 9.26% 18.144%

Relationships between endpoints

Index endpoint: M13_DISCINFECTION – Infection of intervertebral disc (pyogenic)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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