No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
398 |
4. Check minimum number of eventsNone |
398 |
5. Include endpointsNone |
398 |
6. Filter based on genotype QC (FinnGen only) |
365 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M62
- Name in latin
- Diastasis musculi
Similar endpoints
↥List of similar endpoints to
Diastasis of muscle
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1432 | 834 | 588 |
| Only index persons | 1376 | 813 | 563 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.12 | 41.83 | 57.15 |
| Only index persons | 48.03 | 41.56 | 57.37 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 365 | 249 | 116 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.05 |
| Median age at first event (years) | 49.37 | 43.25 | 62.51 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 379
- Matched controls
- 3790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M62.0
ICD-10 Finland
Diastasis of muscle
4503599627370496.0
307.7
378
6
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
15.2
103.7
103
91
QBJ30
NOMESCO Finland
Correction of abdominal apron
169.0
98.6
100
8
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
15.9
82.7
77
60
JAG96
NOMESCO Finland
Other reconstruction of abdominal wall
707.4
62.7
60
*
M79.6
ICD-10 Finland
Pain in limb
3.5
31.2
192
869
N02AX02
ATC
tramadol; systemic, rectal
3.5
31.2
188
840
JAF10
NOMESCO Finland
Repair of umbilical hernia
8.7
25.1
33
41
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.0
24.0
186
927
JN3AD
NOMESCO Finland
Abdominal CT examination
4.1
23.2
74
213
M99.8
ICD-10 Finland
Other biomechanical lesions
127.8
22.9
24
*
N03AX12
ATC
[U] gabapentin; oral
4.0
22.3
72
209
WX402
NOMESCO Finland
General anaesthesia
3.1
21.9
126
528
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.4
20.6
91
325
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.3
20.4
44
92
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.0
20.1
113
464
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
19.7
118
502
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
19.1
110
457
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
5.2
17.7
38
79
G47.3
ICD-10 Finland
Sleep apnoea
2.9
17.5
104
437
E66.8
ICD-10 Finland
Other obesity
4.5
17.3
45
110
S18
ICPC
Laceration/cut
2.5
17.3
190
1081
K42
ICD-10 Finland
Umbilical hernia
17.0
17.3
27
17
N02BE01
ATC
paracetamol; systemic, rectal
6.4
16.9
361
2878
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.6
16.9
33
63
SPAT1249
SPAT
Treatment-related counselling outside office
2.5
16.7
179
1002
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
16.7
179
1003
SPAT1263
SPAT
Sampling
2.4
15.9
180
1028
UJF32
NOMESCO Finland
Coloscopy
2.7
15.6
102
448
M54.5
ICD-10 Finland
Low back pain
2.4
15.5
162
890
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
15.4
176
1005
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
4.8
15.3
36
81
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
21.1
15.3
22
11
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
5.3
14.8
31
63
K43
ICD-10 Finland
Ventral hernia
23.4
14.4
20
9
R4110, ,
SPAT
3.3
14.2
58
195
N03AX16
ATC
[U] pregabalin
2.8
14.0
82
338
N06AX21
ATC
duloxetine; oral
3.3
14.0
58
196
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
13.8
45
130
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.6
13.8
48
145
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.1
13.8
64
232
SPAT1310
SPAT
Counselling related to known health issue
2.4
13.5
131
689
M25.5
ICD-10 Finland
Pain in joint
2.3
13.1
138
749
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
13.0
143
790
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
12.8
42
122
O82.0
ICD-10 Finland
Delivery by elective caesarean section
3.7
12.8
42
122
SPAT1153
SPAT
Removal of sutures
2.4
12.6
119
615
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
12.6
51
170
M79.7
ICD-10 Finland
Fibromyalgia
13.0
12.3
21
17
L03
ICPC
Low back symptom/complaint
2.3
12.2
125
668
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.7
12.2
41
121
A02BC02
ATC
pantoprazole; systemic
2.2
12.1
256
1822
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.2
12.0
53
186
SPAT1262
SPAT
Handing over of treatment supplies
2.7
11.9
74
313
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.1
11.9
196
1263
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.9
11.8
60
228
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.0
11.7
35
95
M79.1
ICD-10 Finland
Myalgia
2.7
11.7
69
285
R03AC02
ATC
salbutamol; inhalant
2.1
11.5
229
1580
R51.80
ICD-10 Finland
Headache
2.6
11.4
76
333
N02BF01
ATC
gabapentin; oral
3.5
11.3
42
132
E66.01
ICD-10 Finland
Obesity due to excess calories
2.9
11.3
60
234
H02AB06
ATC
prednisolone; systemic
2.1
11.3
176
1105
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.7
11.0
36
104
SPAT1377
SPAT
Polysomnography
5.6
11.0
21
39
A02BC05
ATC
esomeprazole; systemic
2.1
11.0
153
918
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
10.9
63
256
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
10.9
82
381
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
18.5
10.8
16
9
M79.0
ICD-10 Finland
Rheumatism, unspecified
29.0
10.8
14
5
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
11.7
10.7
19
17
L08
ICPC
Shoulder symptom/complaint
2.4
10.7
82
384
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.0
10.5
31
83
M62.1
ICD-10 Finland
Other rupture of muscle (nontraumatic)
113.0
10.5
11
*
O30.0
ICD-10 Finland
Twin pregnancy
8.6
10.5
22
27
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
33.5
10.4
13
*
J01DB01
ATC
cefalexin; oral
2.7
10.3
327
2658
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
10.3
169
1072
SPAT1301
SPAT
No procedures
2.2
10.2
119
664
N62
ICD-10 Finland
Hypertrophy of breast
4.3
10.1
27
67
B01AB05
ATC
enoxaparin; parenteral
2.2
10.0
116
645
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.9
9.9
49
183
WX320
NOMESCO Finland
Spinalanesthesy
2.2
9.9
99
519
SPAT1058
SPAT
PEF monitoring instruction
3.6
9.8
34
102
R20.2
ICD-10 Finland
Paraesthesia of skin
3.6
9.8
34
102
SAA01
NOMESCO Finland
Simple examination of mouth
2.3
9.8
296
2323
JAG60
NOMESCO Finland
Reconstruction of abdominal wall using prosthetic material
56.5
9.7
11
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.8
9.7
22
48
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.0
9.5
44
158
J01FF01
ATC
clindamycin; systemic
2.1
9.3
104
567
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
9.3
85
427
J01AA02
ATC
doxycycline; systemic
2.2
9.3
290
2276
L28
ICPC
Limited function/disability (L)
2.5
9.3
63
277
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.3
9.2
78
380
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.7
9.2
52
209
M70.6
ICD-10 Finland
Trochanteric bursitis
3.0
9.0
41
146
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.1
9.0
25
64
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
8.3
9.0
19
24
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
8.8
73
352
ACC51
NOMESCO Finland
Release of median nerve
3.6
8.7
29
85
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
4.2
8.7
23
57
L29
ICPC
Musculoskeletal sympt/complt other
3.0
8.6
39
139
SPAT1211
SPAT
Application of soft bandage
3.2
8.6
35
117
SPAT1312
SPAT
General health counselling
2.0
8.5
126
759
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
8.5
44
169
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
8.4
100
557
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
4.0
8.4
24
63
WZC00, ,
SPAT
2.4
8.3
60
272
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
14.9
8.3
13
9
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.7
8.3
27
78
M77.1
ICD-10 Finland
Lateral epicondylitis
3.1
8.2
35
120
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.1
8.2
35
120
WX723
NOMESCO Finland
CPAP therapy
3.9
8.2
24
64
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.9
8.1
39
143
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
34.1
8.1
10
*
A02BA02
ATC
ranitidine; systemic
2.4
8.0
62
289
J02AC01
ATC
fluconazole; systemic
1.9
8.0
173
1178
T82
ICPC
Obesity
3.6
8.0
26
75
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.2
7.9
32
106
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
7.9
91
499
M65.3
ICD-10 Finland
Trigger finger
7.2
7.9
18
26
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.3
7.8
20
48
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.3
7.8
64
307
M67.4
ICD-10 Finland
Ganglion
3.9
7.7
23
62
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
45.9
7.7
9
*
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
7.7
85
458
SPAT1379
SPAT
Health check-up of pregnant person
2.1
7.7
84
452
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
7.7
84
452
C10AX09
ATC
ezetimibe; oral
2.4
7.7
55
248
JAF11
NOMESCO Finland
Laparoscopic repair of umbilical hernia
18.8
7.6
11
6
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
7.6
94
528
N06AX11
ATC
mirtazapine; oral
1.9
7.6
131
826
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
7.6
108
639
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
7.5
83
447
A01
ICPC
Pain general/multiple sites
2.8
7.5
38
144
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.3
7.5
61
291
M54.4
ICD-10 Finland
Lumbago with sciatica
2.2
7.5
66
326
E66.9
ICD-10 Finland
Obesity, unspecified
3.5
7.4
25
74
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
7.3
44
182
SFA20
NOMESCO Finland
Two-surface restoration
1.8
7.3
240
1840
K59.09
ICD-10 Finland
Constipation, unspecified
3.6
7.2
24
70
J01FA10
ATC
azithromycin; systemic
1.8
7.2
227
1712
TQW40, ,
SPAT
2.6
7.2
43
177
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.4
7.2
55
255
L57.4
ICD-10 Finland
Cutis laxa senilis
30.6
7.2
9
*
J01MA12
ATC
levofloxacin; systemic
2.3
7.2
61
296
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
8.2
7.2
15
19
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
7.1
136
883
C03CA01
ATC
furosemide; systemic
2.1
7.1
80
434
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
7.1
150
1004
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.6
7.1
44
185
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
4.0
7.1
20
52
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
6.5
7.0
17
27
R06.5
ICD-10 Finland
Mouth breathing
2.8
7.0
35
132
M03BX02
ATC
tizanidine; oral
1.8
6.9
236
1813
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.0
6.9
31
110
XA402
NOMESCO Finland
ENMG
9.6
6.8
13
14
N02BF02
ATC
pregabalin; oral
3.4
6.8
25
78
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.6
6.8
40
164
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
6.8
214
1605
I49.3
ICD-10 Finland
Ventricular premature depolarization
3.0
6.7
30
106
K07.60
ICD-10 Finland
Snapping jaw
3.1
6.7
28
95
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
6.1
6.7
17
29
M01AE02
ATC
naproxen; oral, rectal
1.8
6.7
210
1570
SPAT1380
SPAT
Postpartum check-up
2.1
6.6
75
407
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.2
6.6
64
327
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
4.3
6.6
17
41
S97
ICPC
Chronic ulcer skin
3.2
6.6
26
85
S04
ICPC
Lump/swelling localized
2.4
6.6
47
211
M01AH01
ATC
celecoxib; oral
2.3
6.6
53
251
WZB00, ,
SPAT
2.5
6.6
41
173
Z01.2
ICD-10 Finland
Dental examination
1.7
6.5
180
1295
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
6.5
203
1511
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
6.5
87
502
S21
ICPC
Skin texture symptom/complaint
2.2
6.4
58
288
T90
ICPC
Diabetes non-insulin dependent
2.0
6.4
80
450
-54
ICPC
Repair/fix-suture/cast/prosth device
8.4
6.4
13
16
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
6.3
279
2283
L17
ICPC
Foot/toe symptom/complaint
1.9
6.3
102
624
B80
ICPC
Iron deficiency anaemia
4.0
6.3
18
47
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
6.3
74
407
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
3.6
6.2
20
57
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
6.2
87
508
SPAT1196
SPAT
Monitoring of normal pregnancy
2.2
6.2
54
264
M02AA10
ATC
ketoprofen; topical
2.3
6.2
49
230
SPAT1254
SPAT
Administration of medicine
2.4
6.2
46
210
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
6.2
67
357
A10BA02
ATC
metformin; oral
1.9
6.2
96
580
205
Kela drug reimbursment
Chronic hypertension
2.1
6.2
66
350
J01DA01
ATC
[U] cefalexin
1.7
6.2
222
1709
M77.4
ICD-10 Finland
Metatarsalgia
3.2
6.2
24
78
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.3
6.2
49
231
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
6.1
118
762
D91
ICPC
Abdominal hernia other
8.8
6.1
12
14
SPAT1229
SPAT
Assessment of need for aid
3.5
6.1
21
63
ZXE00
NOMESCO Finland
One hour or less
1.7
6.1
149
1031
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
6.1
42
186
SPAT1238
SPAT
Brief therapy
6.2
6.1
15
25
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
6.0
55
274
A02BC04
ATC
rabeprazole; oral
2.5
6.0
38
161
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
266
1543
3.43
27.34
3.0
2.7
—
—
estimate
—
0
0
175
882
2.83
21.56
5.1
3.4
0.00
0.01
estimate
0.99
70
330
173
869
2.82
21.42
3.0
2.3
55.87
68.40
u/l
0.89
157
821
210
1166
2.80
21.40
15.7
11.3
1.19
1.19
inr
0.06
188
952
82
269
3.61
21.19
4.2
2.7
—
—
—
0
0
264
1716
2.77
18.68
5.2
4.7
6.41
6.53
mmol/l
0.41
243
1575
219
1305
2.61
18.43
4.8
3.2
0.00
0.03
estimate
1.13
70
309
234
1492
2.49
16.27
5.9
6.5
10.23
11.45
umol/l
1.40
222
1431
249
1686
2.39
14.35
4.9
3.2
0.00
0.00
estimate
0.50
74
351
250
1701
2.38
14.17
4.9
3.2
0.00
0.00
estimate
-0.00
74
347
197
1221
2.28
13.82
4.6
4.8
36.79
36.36
g/l
0.51
184
1157
250
1718
2.34
13.59
5.0
3.3
0.00
0.02
estimate
0.79
72
331
304
2289
2.66
13.29
4.4
3.6
9.78
10.42
mm/h
0.41
290
2149
303
2291
2.61
12.90
8.1
7.4
72.09
76.87
u/l
1.61
291
2182
167
995
2.21
12.58
4.6
3.2
33.95
43.88
ng/l
0.24
106
597
143
806
2.24
12.30
3.2
2.0
2.92
2.69
mg/l
0.83
124
708
55
197
3.10
12.03
3.0
3.7
1.23
1.22
mmol/l
0.10
49
175
116
605
2.32
11.95
2.3
1.7
431.51
34066344.03
pmol/l
0.77
95
546
114
596
2.31
11.64
3.1
2.4
6.71
7.20
e6/l
0.09
106
531
369
3192
6.91
11.08
19.7
13.3
139.69
139.61
mmol/l
0.35
362
3133
369
3195
6.87
11.00
19.6
13.4
3.94
3.93
mmol/l
0.13
362
3123
83
392
2.43
10.58
2.3
2.3
28.01
23.46
%
1.40
75
371
199
1334
2.04
10.41
5.9
6.9
1.21
1.21
mmol/l
0.09
161
1170
108
585
2.18
9.92
1.5
1.2
29.04
30.63
iu/ml
0.04
26
164
367
3211
5.51
9.72
17.5
12.0
19.16
22.25
mg/l
1.23
325
2562
321
2611
2.50
9.70
5.4
4.4
14.57
14.43
pmol/l
0.52
293
2449
137
819
2.05
9.68
1.4
1.3
3.65
2.04
u/ml
0.35
55
242
159
1004
2.01
9.64
4.1
2.7
0.01
0.02
estimate
0.06
68
289
155
970
2.01
9.64
2.3
3.3
2.33
2.34
mmol/l
1.13
146
913
248
1828
2.03
9.62
4.2
3.1
92.00
89.37
ug/l
0.11
234
1745
245
1807
2.01
9.37
5.7
9.3
4.19
4.08
e9/l
0.38
224
1578
92
478
2.22
9.31
2.4
2.3
14.23
14.05
umol/l
0.08
85
449
86
439
2.24
9.07
2.4
2.2
2.39
2.36
g/l
0.19
79
410
180
1211
1.93
8.87
2.3
1.9
95.31
94.82
pmol/l
0.04
102
677
148
936
1.95
8.74
3.4
3.2
8.05
8.02
mmol/l
0.03
128
815
78
391
2.25
8.56
2.2
1.6
1452.45
1165.27
nmol/l
1.43
59
305
354
3075
3.29
8.41
15.1
11.1
88.13
87.91
ml/min/173m2
0.07
335
2793
128
785
1.95
8.17
2.1
1.6
22.07
19.94
nmol/l
0.76
112
682
124
757
1.95
7.99
1.9
2.0
129.81
222.40
u/l
1.42
115
716
172
1171
1.86
7.91
5.6
6.3
1.21
1.21
mmol/l
0.34
166
1099
120
728
1.95
7.86
4.8
3.3
1.02
1.02
kg/l
0.06
88
497
113
672
1.97
7.84
3.4
3.6
700.52
1155.26
ng/l
1.51
88
570
152
1002
1.86
7.69
3.5
2.8
—
—
—
0
0
16
20
8.30
7.67
1.3
2.0
90.28
89.13
%
0.25
16
20
193
1372
1.83
7.64
3.0
2.4
75.77
74.62
nmol/l
0.22
182
1275
44
181
2.62
7.41
1.7
1.7
—
—
—
0
0
370
3424
4.39
7.06
13.3
9.8
25.32
25.63
u/l
0.17
360
3349
348
3062
2.67
6.78
6.4
5.1
1.73
1.80
mu/l
0.66
323
2894
130
847
1.81
6.64
4.5
4.0
3.21
9.18
mg/mmol
3.14
80
552
120
765
1.83
6.57
3.1
2.7
0.16
0.37
e6/l
2.30
105
532
49
225
2.35
6.54
1.4
1.2
174.33
270.33
u/ml
0.35
44
204
89
519
1.93
6.40
1.5
1.2
3.09
12.28
u/ml
1.81
36
209
55
271
2.20
6.22
10.0
6.3
—
—
—
0
0
45
204
2.37
6.18
1.5
1.6
—
—
—
0
0
334
2941
2.14
5.58
7.3
5.1
38.49
37.86
mmol/mol
0.78
326
2807
341
3030
2.25
5.50
5.9
4.2
5.82
5.75
mmol/l
0.52
318
2834
152
1090
1.66
5.26
3.1
3.3
30.25
31.51
u/l
0.24
140
1053
107
703
1.73
5.12
2.6
2.6
336.55
329.71
umol/l
0.33
94
646
25
94
2.78
5.02
2.2
1.6
38.40
41.11
nmol/l
0.25
25
94
20
67
3.10
4.90
2.3
1.4
—
—
—
0
0
113
770
1.67
4.67
2.4
2.1
—
—
—
0
0
11
18
6.26
4.63
1.3
1.6
—
—
—
0
0
32
145
2.32
4.42
1.5
1.6
70.08
54.90
ug/l
0.60
32
145
30
133
2.36
4.35
2.2
4.9
1.26
1.46
mmol/l
0.10
19
98
9
13
7.06
4.18
1.0
1.0
—
—
—
0
0
100
680
1.64
4.11
1.7
1.6
0.93
1.17
mg/l
0.73
77
521
28
125
2.34
4.01
1.8
1.7
—
—
—
0
0
270
2310
1.59
3.98
4.4
3.0
43.18
41.68
u/l
0.15
256
2224
31
147
2.21
3.87
3.1
3.2
133.00
130.11
g/l
0.27
31
139
51
291
1.87
3.86
1.3
1.3
120.49
182.60
u/ml
0.62
22
120
15
49
3.15
3.85
1.2
2.0
—
—
—
0
0
52
301
1.84
3.76
1.6
1.7
—
—
—
0
0
278
2415
1.57
3.64
3.7
3.6
—
—
—
0
0
19
74
2.65
3.61
1.8
1.4
271.77
297.61
ug/g
0.26
13
42
42
233
1.90
3.47
2.6
3.6
2.23
1.55
mmol/l
0.61
35
191
65
415
1.68
3.37
1.7
1.9
—
—
—
0
0
13
38
3.51
3.34
1.2
1.6
—
—
—
0
0
79
532
1.61
3.33
1.9
2.5
2.43
2.42
mmol/l
0.20
71
477
164
1295
1.47
3.31
2.1
1.8
1.47
1.32
mmol/l
1.30
129
1122
20
85
2.43
3.21
1.2
1.7
—
—
—
0
0
10
25
4.08
3.10
2.0
2.4
0.85
0.14
mmol/l
—
10
25
6
8
7.60
3.06
1.2
1.8
—
—
—
0
0
6
8
7.60
3.06
1.2
1.9
—
—
—
0
0
32
169
1.98
3.06
2.6
2.1
3.91
8.59
ug/l
1.64
32
151
66
434
1.63
3.05
1.5
1.6
1340.33
1021.10
mu/l
1.47
52
354
24
114
2.18
3.01
2.1
3.6
25.11
24.80
mmol/l
0.15
24
107
12
37
3.32
2.96
1.3
1.7
—
—
—
0
0
42
248
1.78
2.87
2.0
2.1
13307.82
7417.41
u/l
0.38
11
113
38
218
1.83
2.85
2.8
2.6
66.41
68.79
ml/min/173m2
0.12
17
94
28
145
2.01
2.83
1.5
1.4
—
—
—
0
0
12
39
3.14
2.79
1.2
1.1
—
—
—
0
0
348
3256
1.84
2.75
6.2
4.7
2.83
2.77
mmol/l
0.52
325
3100
26
134
2.01
2.67
2.7
2.9
0.65
0.62
%
0.18
26
134
46
285
1.70
2.67
1.6
1.8
—
—
—
0
0
109
827
1.45
2.60
1.9
1.6
—
—
—
0
0
16
68
2.41
2.59
2.3
2.8
—
—
—
0
0
26
136
1.98
2.57
2.7
3.0
1.15
1.22
%
0.19
26
136
19
88
2.22
2.55
1.2
2.6
3.88
5.56
umol/l
0.83
12
66
52
339
1.62
2.50
7.1
7.0
104.21
104.61
mmol/l
0.29
52
339
8
21
3.87
2.47
1.1
1.8
—
0.67
—
0
6
7
17
4.17
2.37
1.1
1.5
—
—
—
0
0
7
17
4.17
2.37
1.1
1.5
—
—
—
0
0
16
72
2.28
2.31
1.4
1.1
—
—
—
0
0
327
3044
1.54
2.22
4.8
3.7
1.30
1.23
mmol/l
1.18
307
2875
30
174
1.79
2.21
1.9
1.8
—
—
—
0
0
17
81
2.15
2.16
1.3
1.3
—
—
—
0
0
16
75
2.18
2.11
1.2
1.4
—
—
—
0
0
342
3223
1.63
2.11
5.9
4.3
4.69
4.68
mmol/l
0.04
319
3071
13
56
2.37
2.07
4.2
3.4
8.92
9.26
pmol/l
0.04
13
56
6
15
4.05
2.04
1.3
1.5
—
—
—
0
0
6
15
4.05
2.04
1.3
1.5
—
—
—
0
0
17
83
2.10
2.04
1.2
1.6
—
—
—
0
0
61
433
1.49
2.03
1.7
1.8
1.34
1.40
%
0.37
56
386
31
188
1.71
1.98
2.2
2.3
9.02
10.44
au/ml
—
5
19
12
51
2.40
1.97
1.8
1.8
—
—
—
0
0
340
3211
1.57
1.94
5.7
4.2
1.43
1.47
mmol/l
1.43
316
3041
47
319
1.54
1.93
1.3
1.3
22.05
21.97
iu/l
0.01
41
289
25
145
1.78
1.86
13.9
7.1
24.55
24.09
mmol/l
0.23
25
137
6
17
3.57
1.84
1.5
1.2
—
—
—
0
0
17
87
2.00
1.83
1.1
1.1
—
—
—
0
0
17
87
2.00
1.83
1.1
1.1
—
—
—
0
0
47
324
1.51
1.81
3.0
2.6
10.84
7.42
umol/l
0.39
40
285
13
60
2.21
1.80
1.2
1.5
—
—
—
0
0
14
67
2.13
1.78
1.2
1.4
—
—
—
0
0
31
195
1.64
1.75
1.0
1.0
—
—
—
0
0
29
181
1.65
1.69
1.4
1.4
—
—
—
0
0
13
62
2.14
1.67
1.1
1.0
—
—
—
0
0
6
19
3.19
1.66
1.3
1.5
—
—
—
0
0
45
314
1.49
1.64
5.9
4.2
32.97
31.98
%
0.30
36
213
98
785
1.34
1.64
6.1
5.3
1.77
2.56
ug/l
0.90
92
709
11
50
2.24
1.58
1.2
1.5
—
—
—
0
0
7
27
2.62
1.52
1.7
1.4
—
—
—
0
0
6
21
2.89
1.51
1.5
1.1
—
—
—
0
0
17
94
1.85
1.50
2.6
1.5
1.23
1.20
g/l
0.16
17
89
10
45
2.26
1.47
4.0
2.0
13.22
13.15
%
—
10
45
32
213
1.55
1.46
1.8
1.4
—
—
—
0
0
7
28
2.53
1.46
1.7
1.4
—
—
—
0
0
7
28
2.53
1.46
1.7
1.4
—
—
—
0
0
10
46
2.21
1.41
1.9
1.5
—
—
—
0
0
7
29
2.44
1.40
1.7
1.3
—
—
—
0
0
7
29
2.44
1.40
1.7
1.3
—
—
—
0
0
7
29
2.44
1.40
1.7
1.3
—
—
—
0
0
7
29
2.44
1.40
3.4
4.7
2.19
186.80
nmol/l
—
7
29
6
23
2.63
1.37
1.0
1.3
—
—
—
0
0
6
25
2.42
1.25
1.2
1.1
—
—
—
0
0
79
639
1.30
1.23
4.9
4.6
20.23
21.50
%
0.42
40
297
5
19
2.65
1.22
1.0
2.4
11.60
16.26
%
—
5
19
27
389
0.67
1.20
1.6
1.7
3.58
3.34
mmol/l
0.56
21
276
24
158
1.55
1.18
11.2
11.3
93.55
93.37
%
0.07
24
158
32
228
1.44
1.10
9.5
8.8
129.22
120.10
g/l
1.49
32
223
5
21
2.40
1.09
1.2
2.3
—
—
—
0
0
73
596
1.28
1.06
1.8
2.0
—
—
—
0
0
23
155
1.52
1.04
3.0
1.8
—
—
—
0
0
9
47
1.94
1.03
1.6
1.3
—
—
—
0
0
39
295
1.36
0.97
1.4
1.5
—
—
—
0
0
16
102
1.59
0.92
2.1
2.0
3.77
1.26
ug/l
0.38
16
89
25
178
1.43
0.89
1.9
1.9
5.16
3.42
mg/l
0.22
19
125
12
72
1.69
0.86
1.2
1.2
246.14
215.88
u/ml
—
7
42
40
507
0.76
0.85
1.7
1.9
3.46
3.37
ratio
0.27
34
395
6
31
1.95
0.84
1.3
3.0
1.21
1.17
mmol/l
—
6
31
6
31
1.95
0.84
1.3
3.0
108.83
105.13
mmol/l
—
6
31
78
661
1.23
0.84
1.9
2.1
—
—
—
0
0
16
107
1.52
0.77
1.2
1.1
—
10.81
—
0
20
9
54
1.68
0.75
1.2
1.4
—
—
—
0
0
10
61
1.66
0.69
1.3
1.3
—
—
—
0
0
5
27
1.86
0.68
1.2
1.2
—
—
—
0
0
21
153
1.39
0.68
2.2
1.6
0.18
0.33
mg/l
—
10
68
12
79
1.54
0.63
1.2
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
11
72
1.54
0.59
1.4
1.5
164.00
168.14
au/ml
—
5
17
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
55
469
1.20
0.58
2.4
2.4
0.78
1.08
e6/l
0.60
36
235
6
36
1.68
0.57
1.2
1.2
—
—
—
0
0
5
88
0.56
0.56
1.2
2.0
2.80
3.55
g/l
—
5
83
5
88
0.56
0.56
1.2
2.0
4.56
4.49
g/l
—
5
83
57
490
1.19
0.55
3.1
3.3
290.83
510.73
ng/l
0.45
36
327
23
180
1.30
0.51
1.5
1.4
178.78
252.50
miu/ml
0.50
11
99
9
65
1.39
0.51
1.7
2.1
—
—
—
0
0
12
84
1.44
0.50
1.4
1.3
—
17.27
—
0
17
12
84
1.44
0.50
1.3
1.3
—
4.95
—
0
10
13
176
0.73
0.47
1.0
1.1
1.42
1.57
g/l
1.60
13
176
7
49
1.44
0.46
1.0
1.2
15.83
19.56
u/l
—
7
43
5
31
1.62
0.43
1.0
1.5
—
—
—
0
0
5
33
1.52
0.41
1.8
1.2
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
18
144
1.26
0.36
3.1
3.3
25.28
23.95
mmol/l
1.32
18
144
13
99
1.32
0.36
1.3
1.3
—
—
—
0
0
17
139
1.23
0.29
2.5
3.2
44.83
159.51
ng/l
2.86
12
121
15
122
1.24
0.27
3.1
2.3
2.42
5.33
iu/l
—
9
54
15
180
0.83
0.24
1.0
1.2
0.88
0.88
g/l
0.03
15
180
16
133
1.21
0.24
9.4
12.5
17.30
15.64
%
1.50
16
127
15
125
1.21
0.22
1.4
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
3.0
—
36.27
—
0
11
0
11
0.00
0.21
0.0
1.0
—
6.41
—
0
11
0
10
0.00
0.21
0.0
1.2
—
406.80
—
0
5
8
103
0.77
0.21
1.6
1.5
—
0.01
—
0
17
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
82
775
1.07
0.20
1.5
1.6
—
—
—
0
0
41
445
0.91
0.19
2.5
2.5
3.06
3.25
e6/l
0.05
21
214
8
70
1.15
0.16
1.4
1.3
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
14
126
1.12
0.09
1.2
1.2
—
—
—
0
0
5
64
0.78
0.08
1.2
1.2
—
—
—
0
0
9
87
1.04
0.07
1.2
1.5
—
—
—
0
0
29
276
1.05
0.06
1.6
1.5
75.92
58.54
ug/l
0.72
20
228
17
182
0.93
0.05
1.4
1.6
—
—
—
0
0
38
389
0.97
0.02
1.8
1.8
—
—
—
0
0
49
483
1.02
0.01
3.4
3.1
0.61
0.77
ug/l
1.06
34
308
16
154
1.04
0.00
1.2
1.4
—
—
—
0
0
48
478
1.00
0.00
1.9
1.9
—
—
—
0
0
26
261
1.00
0.00
1.5
1.5
1.18
1.08
ratio
0.17
17
163
26
261
1.00
0.00
1.5
1.5
0.96
0.96
ratio
0.01
17
163
26
261
1.00
0.00
1.5
1.5
—
—
—
0
0
26
261
1.00
0.00
1.5
1.5
1.22
1.18
ratio
0.08
17
164
12
125
0.96
0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
10.67
—
0
7
7
74
0.94
-0.00
1.4
1.2
—
47.55
—
0
10
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
8
82
0.98
-0.00
1.3
1.1
—
3.53
—
0
18
10
100
1.00
-0.00
1.6
1.9
—
—
—
0
0
9
93
0.97
-0.00
1.4
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
59
0.85
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.8
—
20.40
—
0
5
5
53
0.94
-0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
35.80
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_DIASTASIS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DIASTASIS | 0.982 [0.75, 1.28] | 0.891 |
| Birth year | 0.99 [0.98, 1.0] | 0.051 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 493 males with M13_DIASTASIS died.
Mortality risk
Mortality risk for people of age
years, who have M13_DIASTASIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.197% |
| 5 | No data | 1.252% |
| 10 | No data | 3.111% |
| 15 | No data | 5.867% |
| 20 | No data | 10.226% |
Relationships between endpoints
↥Index endpoint: M13_DIASTASIS – Diastasis of muscle
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data