Idiopathic pulmonary fibrosis

IPF

idiopathic pulmonary fibrosis: Idiopathic pulmonary fibrosis (IPF) is a nonneoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known cause.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J84.1
  • Cause of death: ICD-10 J84.1

2 out of 7 registries used, show all original rules.

3634

4. Check minimum number of events

None

3634

5. Include endpoints

None

3634

6. Filter based on genotype QC (FinnGen only)

3149

Control definitions (FinnGen only)

Control exclude
ILD_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze
DF5
Parent code in ICD-10
J84
Name in latin
Morbus pulmonum interstitialis cum fibrosi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 18549 7438 10834
Only index persons 13181 5367 7814
Unadjusted period prevalence (%)
Whole population 0.27 0.21 0.30
Only index persons 0.26 0.20 0.30
Median age at first event (years)
Whole population 74.28 75.14 73.71
Only index persons 74.01 74.46 73.69

-FinnGen-

Key figures

All Female Male
Number of individuals 3149 1070 2079
Unadjusted period prevalence (%) 0.76 0.38 0.95
Median age at first event (years) 73.02 71.34 73.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3244
Matched controls
32440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
92.6
319.4
167
19
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
40.7
309.0
188
49
L04AA06
ATC
mycophenolic acid; systemic
18.1
307.7
288
174
356
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
307.7
609
*
TGC00
NOMESCO Finland
Bronchial lavation
29.1
307.7
693
300
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
+∞
307.7
518
*
GD1AD
NOMESCO Finland
Thorax CT examination
6.9
307.7
684
1213
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
4503599627370496.0
307.7
3241
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
9.9
307.7
1163
1741
H02AB06
ATC
prednisolone; systemic
5.0
307.7
2422
11993
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
11.8
307.7
425
408
L04AX05
ATC
pirfenidone; oral
+∞
307.7
409
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.7
307.7
1173
2535
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.8
307.7
839
1855
284
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
307.7
630
*
J96.1
ICD-10 Finland
Chronic respiratory failure
12.4
307.7
448
413
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
7.0
307.7
559
933
XG410
NOMESCO Finland
Flow-volume spirometry
10.2
307.7
546
629
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
19.9
307.7
620
381
L01EX09
ATC
nintedanib; oral
+∞
307.7
307
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
3915.4
307.7
1430
7
L04AX01
ATC
azathioprine; systemic
9.7
307.7
415
482
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
26.8
307.7
1280
769
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
33.6
286.8
184
58
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.5
272.5
1764
8177
R06.0
ICD-10 Finland
Dyspnoea
3.5
259.5
1588
7055
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
225.1
2339
13844
L01XE31
ATC
[U] nintedanib
+∞
218.2
207
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.3
186.6
554
1486
R03AC02
ATC
salbutamol; inhalant
2.9
183.1
2063
12168
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.9
176.1
423
958
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
6.7
167.1
277
444
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
13.5
156.9
149
115
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
10.2
152.1
175
181
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
13.3
138.9
133
104
GX1D5
NOMESCO Finland
Flow volume spirometry
42.6
138.3
83
20
GX1K5
NOMESCO Finland
Diffusion capacity
19.9
136.8
106
55
WX721
NOMESCO Finland
Oxygen concentrator therapy
34.0
135.0
86
26
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.2
132.5
383
996
127
Kela drug reimbursment
Transplant complication
11.2
131.1
140
130
GDG10
NOMESCO Finland
Bilateral transplantation of lung
430.6
125.7
125
*
Z94.2
ICD-10 Finland
Lung transplant status
170.6
125.3
131
8
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.1
124.2
633
2377
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
1212.4
120.6
117
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.2
115.9
332
855
R03BB04
ATC
tiotropium bromide; inhalant
2.9
115.5
672
2706
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.9
112.0
257
555
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
110.2
1486
8800
P01BA02
ATC
hydroxychloroquine; oral
3.6
109.6
394
1189
J01MA14
ATC
moxifloxacin; systemic
3.1
108.0
510
1823
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
99.1
932
4696
R99
ICPC
Respiratory disease other
6.4
98.1
166
270
L04AD01
ATC
ciclosporin; systemic
8.2
97.0
131
166
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
14.5
94.8
86
61
J84.0
ICD-10 Finland
Alveolar and parietoalveolar conditions
+∞
93.2
89
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
21.0
92.8
70
34
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.8
91.4
294
820
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.3
87.4
240
596
J43.9
ICD-10 Finland
Emphysema, unspecified
5.7
85.7
163
297
N02AA01
ATC
morphine; systemic, rectal
4.8
81.3
192
423
R05
ICD-10 Finland
Cough
2.2
80.0
827
4283
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
79.3
778
3941
XG466
NOMESCO Finland
Sleep oxymetry
4.5
78.3
198
461
M05BA04
ATC
alendronic acid; oral
2.7
77.6
473
1923
L04AD02
ATC
tacrolimus; systemic
11.4
73.6
77
69
C03CA01
ATC
furosemide; systemic
1.9
73.4
1650
11265
R28
ICPC
Limited function/disability (R)
6.1
72.9
129
219
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
11.1
72.2
77
71
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
70.5
619
2976
WX892
NOMESCO Finland
Monitored bed care
2.7
69.5
408
1623
R02
ICPC
Shortness of breath/dyspnoea
2.3
69.1
632
3089
ZX108
NOMESCO Finland
Inhalation
10.5
68.7
76
74
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.4
67.3
175
416
J47
ICD-10 Finland
Bronchiectasis
5.0
67.0
148
308
R03AK08
ATC
formoterol and beclometasone; inhalant
3.8
66.6
213
589
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
9.0
66.2
82
93
GX2C5
NOMESCO Finland
Short-lasting oximetry
12.5
65.9
65
53
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
4.6
65.5
161
366
L04AA13
ATC
[U] leflunomide
5.4
64.4
129
246
F1246, ,
NOMESCO Finland
27.2
62.8
43
16
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
17.0
62.6
52
31
A02BC02
ATC
pantoprazole; systemic
1.9
60.9
2331
18422
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
23.5
60.9
44
19
R03BA08
ATC
ciclesonide; inhalant
2.8
60.5
322
1213
XX4BW, ,
NOMESCO Finland
108.8
59.0
64
6
L01BA01
ATC
methotrexate; systemic
3.9
58.5
180
484
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
4.7
57.8
138
306
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.0
57.0
277
992
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
56.8
1030
6415
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
56.2
1106
7063
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
53.9
872
5218
WX726
NOMESCO Finland
High-flow oxygen therapy
19.8
52.9
41
21
L04AX03
ATC
methotrexate; systemic
2.6
52.6
343
1429
Z51.5
ICD-10 Finland
Palliative care
2.2
51.8
516
2587
R4110
NOMESCO Finland
Physiotherapy
1.8
51.5
1011
6416
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
51.4
1150
7590
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
20.8
51.4
39
19
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
51.0
803
4748
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.8
50.7
264
981
J01FA06
ATC
roxithromycin; oral
1.8
49.2
1283
8825
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.3
49.0
100
194
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.1
48.8
135
336
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
47.9
840
5129
GDA10
NOMESCO Finland
Biopsy of lung
15.2
47.7
42
28
F2680, ,
NOMESCO Finland
19.7
47.6
37
19
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
7.1
47.5
72
104
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
9.1
47.3
58
65
J01AA02
ATC
doxycycline; systemic
1.9
47.2
2481
20654
L04AA01
ATC
[U] ciclosporin
6.3
47.2
80
130
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
46.8
1543
11275
WW200
NOMESCO Finland
Immunization
4.2
46.4
126
309
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
46.2
295
1215
J01MA12
ATC
levofloxacin; systemic
1.9
45.5
779
4708
A07EC01
ATC
sulfasalazine; oral, rectal
2.5
44.6
291
1210
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.0
44.1
96
197
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.5
44.0
153
447
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
43.4
853
5366
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
42.4
644
3736
R04.2
ICD-10 Finland
Haemoptysis
2.9
42.2
211
766
J80
ICD-10 Finland
Adult respiratory distress syndrome
10.6
42.0
46
44
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.5
41.9
281
1183
D86.0
ICD-10 Finland
Sarcoidosis of lung
6.2
41.7
71
116
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
7.8
41.7
58
76
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
41.5
557
3098
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.5
41.2
102
233
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
41.2
249
997
GX2D5
NOMESCO Finland
Sleep oximetry
9.5
40.7
48
51
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
3.7
40.3
131
366
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
39.8
558
3146
Z57.2
ICD-10 Finland
Occupational exposure to dust
9.5
39.8
47
50
XJC10
NOMESCO Finland
Oesophageal pH monitoring
8.9
39.3
49
56
M05BA07
ATC
risedronic acid; oral
3.2
39.2
157
501
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
38.6
483
2617
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
38.4
1169
8241
M05.1
ICD-10 Finland
Rheumatoid lung disease
197.3
37.9
39
*
5150X
ICD-9 Finland
Postinflammatory pulmonary fibrosis[FIBROSIS PULMONUM E CAUSA IGNOTA]
+∞
37.6
36
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.6
37.2
228
918
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.7
36.5
84
181
M34.1
ICD-10 Finland
CR(E)ST syndrome
11.7
36.1
37
32
J43.8
ICD-10 Finland
Other emphysema
8.8
35.8
45
52
L01AA01
ATC
cyclophosphamide; systemic
7.8
34.0
47
61
Z3226
NOMESCO Finland
Physiotherapist
1.8
34.0
631
3867
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
33.8
643
3970
J84
ICD-10 Finland
Other interstitial pulmonary diseases
330.4
32.9
33
*
J94.1
ICD-10 Finland
Fibrothorax
75.0
32.9
37
5
R81
ICPC
Pneumonia
2.7
32.8
177
668
XG460
NOMESCO Finland
Short time oxymetry
3.7
32.6
103
282
J92.9
ICD-10 Finland
Pleural plaque without asbestos
4.0
32.6
93
237
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.3
32.2
126
397
R5140
NOMESCO Finland
Monitoring the use of the aid
2.0
32.1
400
2156
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
72.9
31.9
36
5
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.2
31.9
287
1370
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
11.5
31.8
33
29
XX9XE
NOMESCO Finland
Other ultrasound examination
7.0
31.8
48
69
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
4.7
31.8
74
161
NH3EA
NOMESCO Finland
Feet X-ray examination with load
4.4
31.4
78
179
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
31.3
299
1461
A02BC05
ATC
esomeprazole; systemic
1.6
31.2
1257
9356
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.9
31.0
151
540
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.8
30.9
160
591
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
30.6
374
2000
J43.2
ICD-10 Finland
Centrilobular emphysema
8.6
30.5
39
46
J96.0
ICD-10 Finland
Acute respiratory failure
3.9
30.5
92
244
R03BA02
ATC
budesonide; inhalant
1.8
30.4
540
3257
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
68.6
29.9
34
5
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
8.9
28.9
36
41
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
6.4
28.6
47
74
J67.9
ICD-10 Finland
Hypersensitivity pneumonitis due to unspecified organic dust
39.3
28.0
35
9
A02BC01
ATC
omeprazole; systemic
1.6
27.4
937
6673
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.6
27.2
157
613
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
26.7
27.1
37
14
5AB14, ,
NOMESCO Finland
75.8
26.8
30
*
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
6.7
26.8
42
63
H02AB07
ATC
prednisone; oral
1.8
26.7
482
2913
XX2RW, ,
NOMESCO Finland
4.5
26.6
65
147
J01CA04
ATC
amoxicillin; systemic
1.6
26.6
2353
20415
A02BC03
ATC
lansoprazole; oral
1.6
26.6
956
6879
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
10.1
26.5
30
30
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.3
26.4
198
875
R05
ICPC
Cough
1.6
26.3
737
5001
A07AA02
ATC
nystatin; oral
2.2
26.2
237
1131
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
26.1
1309
10096
N02AX02
ATC
tramadol; systemic, rectal
1.5
26.1
1407
11015
L88
ICPC
Rheumatoid/seropositive arthritis
2.7
25.9
139
523
I50.0
ICD-10 Finland
Congestive heart failure
1.8
25.5
427
2522
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.0
25.2
277
1424
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
4.6
24.7
58
127
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
24.6
862
6146
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.2
24.3
50
98
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
24.2
544
3485
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
2.9
24.1
116
412
J01FA10
ATC
azithromycin; systemic
1.5
24.1
1358
10668
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.1
23.9
240
1193
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
23.8
454
2782
2AX04, ,
NOMESCO Finland
87.4
23.7
26
*
XG474
NOMESCO Finland
Exhalation nntrogen oxide
3.4
22.8
84
255
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.8
22.7
374
2195
J99.0
ICD-10 Finland
Rheumatoid lung disease
231.6
22.6
23
*
ZXE00
NOMESCO Finland
One hour or less
1.5
22.5
1156
8885
J12.8
ICD-10 Finland
Other viral pneumonia
4.8
22.2
50
106
WX872
NOMESCO Finland
Intensive care
2.1
22.0
218
1078
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.4
21.9
161
705
Z2221
NOMESCO Finland
Medical doctor
1.5
21.8
810
5824
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
21.7
230
1166
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.9
21.4
101
355
M01CB01
ATC
sodium aurothiomalate; parenteral
4.0
21.3
61
156
R03BA01
ATC
beclometasone; inhalant
1.7
21.0
432
2698
3A006, ,
NOMESCO Finland
+∞
20.9
20
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
20.8
243
1276
WPA11
NOMESCO Finland
Developing a plan for palliative care
7.8
20.4
28
36
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
20.4
630
4344
M35.1
ICD-10 Finland
Other overlap syndromes
6.9
20.4
31
45
C07AB07
ATC
bisoprolol; oral
1.4
20.1
1835
15553
M34.0
ICD-10 Finland
Progressive systemic sclerosis
27.2
20.0
27
10
WZA10
NOMESCO Finland
Extensive medical or dental certificate
4.2
20.0
52
124
R50.9
ICD-10 Finland
Fever, unspecified
1.6
20.0
501
3288
RK110, ,
NOMESCO Finland
4.8
19.9
44
92
RS123, ,
NOMESCO Finland
29.1
19.6
26
9
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
4.6
19.1
45
99
AN1
HP
Coronary angiography
1.6
19.1
511
3403
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
3.3
19.0
72
223
WX722
NOMESCO Finland
PEEP
2.1
18.9
177
856
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
55.3
18.9
22
*
R29
ICPC
Respiratory symptom/complaint other
2.0
18.9
210
1083
A01AB09
ATC
miconazole; local oral
1.8
18.9
287
1641
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
2.8
18.9
94
341
Z3231
NOMESCO Finland
Registered nurse
1.5
18.8
870
6506
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
18.2
262
1472
Z2446
NOMESCO Finland
Social worker
2.0
18.0
194
989
ZX120
NOMESCO Finland
Intravenous
1.7
18.0
323
1938
XPX04
NOMESCO Finland
Angioscopy
15.4
17.9
29
19
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
4.8
17.7
40
85
G47.3
ICD-10 Finland
Sleep apnoea
1.5
17.7
635
4506
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.0
17.6
192
984
C01DA14
ATC
isosorbide mononitrate; oral
1.5
17.5
785
5825
R03BA05
ATC
fluticasone; inhalant
1.6
17.4
493
3321
RK320, ,
NOMESCO Finland
4.2
17.2
45
108
R03BB07
ATC
umeclidinium bromide; inhalant
4.2
17.2
45
108
GAA31
NOMESCO Finland
Thoracoscopy
6.4
17.1
28
44
R03DC03
ATC
montelukast; oral
1.6
16.9
389
2494
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
5.0
16.9
36
73
R06AE07
ATC
cetirizine; oral
1.4
16.8
1062
8368
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
16.8
223
1222
XG405
NOMESCO Finland
Education on PEF monitoring
3.4
16.7
59
175
L04AB01
ATC
etanercept; parenteral
4.4
16.6
41
94
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
170.8
16.5
17
*
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.6
16.5
94
366
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.0
16.4
170
855
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
16.3
962
7482
J93.8
ICD-10 Finland
Other pneumothorax
5.0
16.2
34
68
H05AA02
ATC
teriparatide; parenteral
5.8
16.2
29
50
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
4.1
16.1
44
109
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
30.2
16.1
21
7
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
16.1
864
6611
C10AA03
ATC
pravastatin; oral
1.7
16.0
298
1806
J01FA15
ATC
telithromycin; oral
1.8
16.0
239
1359
5BA08, ,
NOMESCO Finland
5.0
15.9
34
69
M81.4
ICD-10 Finland
Drug-induced osteoporosis
5.4
15.9
31
58
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
15.8
273
1619
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
3.3
15.6
57
173
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
85.5
15.6
17
*
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
15.6
908
7041
WPA13
NOMESCO Finland
Palliative consultation
5.1
15.5
32
63
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.5
15.4
484
3332
J67.0
ICD-10 Finland
Farmer lung
14.8
15.3
25
17
SPAT1262
SPAT
Handing over of treatment supplies
1.5
15.3
613
4436
A03
ICPC
Fever
1.6
15.2
375
2441
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
5.5
15.2
29
53
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.2
15.1
135
642
L04AA24
ATC
abatacept; parenteral
10.9
15.0
28
26
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
10.9
15.0
28
26
R4190
NOMESCO Finland
Nutritional therapy
2.4
14.9
107
464
318
Kela drug reimbursment
Teriparatide
5.2
14.8
30
58
GDA97
NOMESCO Finland
Other thoracoscopic incision, excision of lesion or repair of lung
56.9
14.8
17
*
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.6
14.8
403
2687
M33.1
ICD-10 Finland
Other dermatomyositis
25.1
14.7
20
8
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.5
14.6
91
371
J01FF01
ATC
clindamycin; systemic
1.4
14.5
768
5845
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
2.9
14.3
66
230
B01AA03
ATC
warfarin; systemic
1.4
14.3
865
6731
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.7
14.0
72
266
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
4.8
14.0
31
65
WX882
NOMESCO Finland
High dependency care
2.3
14.0
105
465
XX1VW
NOMESCO Finland
Written report from radiologist
4.1
14.0
38
94
1CX01, ,
NOMESCO Finland
15.8
13.9
22
14
XX4AW, ,
NOMESCO Finland
53.6
13.8
16
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
13.8
156
810
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
13.8
569
4134
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.0
13.7
60
203
R03AC19
ATC
olodaterol
5.1
13.6
28
55
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
75.5
13.6
15
*
N02AA05
ATC
oxycodone; systemic
1.4
13.6
722
5490
5163A
ICD-9 Finland
Other alveolar and parietoalveolar pneumopathy, Idiopathic fibrosing alveolitis
+∞
13.5
13
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
13.5
1065
8625
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.6
13.5
80
318
R06.2
ICD-10 Finland
Wheezing
2.1
13.5
132
651
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
2.5
13.4
80
319
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
3.4
13.4
47
139
XX1AW
NOMESCO Finland
Written report from X-ray examination without contrast peformed elsewhere
5.6
13.4
25
45
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
4.9
13.3
29
60
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.0
13.2
152
795
ZX197, ,
NOMESCO Finland
40.2
13.1
16
*
D07AC01
ATC
betamethasone; topical
1.3
13.0
1049
8513
WZC30
NOMESCO Finland
Teaching
1.5
13.0
493
3520
J01FA09
ATC
clarithromycin; systemic
1.4
12.9
721
5520
XF622
NOMESCO Finland
Measurement of minute volume of heart
6.1
12.9
22
36
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
3.4
12.9
45
133
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
2.8
12.8
65
239
M81.9
ICD-10 Finland
Osteoporosis, unspecified
1.9
12.8
156
831
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
3.9
12.8
37
96
J20
ICD-10 Finland
Acute bronchitis
1.7
12.8
269
1683
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
12.7
734
5649
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
12.7
309
2003
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.8
12.7
64
235
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
12.6
184
1039
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
3.4
12.6
45
135
SPAT1325
SPAT
Vaccination
1.3
12.6
1120
9215
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.5
12.5
374
2540
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
12.5
206
1206
SPAT1263
SPAT
Sampling
1.3
12.5
1203
10005
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
12.5
163
889
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
12.5
334
2215
XF600
NOMESCO Finland
Bloodpressure measurement
1.7
12.5
213
1260
AK3
HP
BLTX (both lung transplants)
130.5
12.4
13
*
ZXA10
NOMESCO Finland
Bilateral
1.4
12.4
597
4455
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
12.3
1033
8418
I73.0
ICD-10 Finland
Raynaud syndrome
3.2
12.3
48
152
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
37.7
12.2
15
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.2
12.1
98
449
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.6
12.1
268
1700
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
18.1
12.0
18
10
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
12.0
94
425
R01AD09
ATC
mometasone; nasal
1.3
12.0
1024
8363
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.2
11.9
95
432
WX727
NOMESCO Finland
Estimation of exercise oxygen therapy
46.8
11.9
14
*
GD2SN
NOMESCO Finland
Lung ventilation SPECT
3.6
11.9
38
106
J93.9
ICD-10 Finland
Pneumothorax, unspecified
4.2
11.8
31
75
C10AA01
ATC
simvastatin; oral
1.3
11.7
1606
13967
81
HP
Angiography of the heart and coronary arteries
1.6
11.7
297
1944
Z94.3
ICD-10 Finland
Heart and lungs transplant status
65.2
11.6
13
*
XJC00
NOMESCO Finland
Oesophageal manometry
5.3
11.5
23
44
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
11.5
414
2921
A02BA02
ATC
ranitidine; systemic
1.4
11.5
634
4836
H02AB04
ATC
methylprednisolone; systemic
1.5
11.4
401
2818
R03AC03
ATC
terbutaline; inhalant
1.5
11.2
350
2398
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
2.9
11.2
51
177
TGD00
NOMESCO Finland
Needle biopsy of lung
4.7
11.2
25
53
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
11.1
117
594
B01AC04
ATC
clopidogrel; oral
1.4
11.0
682
5293
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.6
11.0
64
253
WX740
NOMESCO Finland
Nitrogen oxide therapy
13.9
11.0
18
13
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
10.9
786
6244
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.2
10.8
41
128
NG1DA
NOMESCO Finland
X-ray of knees
2.6
10.8
62
244
4040, ,
NOMESCO Finland
21.5
10.7
15
7
R03BB01
ATC
ipratropium bromide; inhalant
1.8
10.6
167
965
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
4.1
10.6
28
68
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.0
10.6
118
611
R94.2
ICD-10 Finland
Abnormal results of pulmonary function studies
4.2
10.5
27
64
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.6
10.5
61
241
XF402
NOMESCO Finland
ECG with work load test
1.5
10.5
357
2492
E84.9
ICD-10 Finland
Cystic fibrosis, unspecified
+∞
10.4
10
*
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
32.6
10.3
13
*
C02KX04
ATC
macitentan; oral
32.6
10.3
13
*
M33.2
ICD-10 Finland
Polymyositis
8.2
10.3
22
27
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.7
10.3
204
1257
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
10.2
161
932
A02BA03
ATC
famotidine; systemic
1.8
10.2
141
785
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.0
10.1
100
497
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
10.1
254
1661
J45.8
ICD-10 Finland
Mixed asthma
2.1
10.0
95
464
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
2.6
9.9
55
213
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.5
9.9
272
1814
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.9
1088
9140
N03AX16
ATC
[U] pregabalin
1.4
9.9
640
4996
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.9
9.8
128
699
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
2.6
9.8
56
220
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
10.6
9.8
18
17
I27.0
ICD-10 Finland
Primary pulmonary hypertension
8.7
9.8
20
23
RS230, ,
NOMESCO Finland
4.5
9.8
23
51
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
9.8
270
1803
L04AB04
ATC
adalimumab; parenteral
3.1
9.7
39
126
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.5
9.7
269
1796
UJF32
NOMESCO Finland
Coloscopy
1.3
9.7
822
6668
WX302
NOMESCO Finland
Thoracal epidural anesthesy
1.7
9.7
160
939
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.7
488
3659
WX720
NOMESCO Finland
Own respiration
1.8
9.6
141
798
J01XB01
ATC
colistin; inhalant, parenteral
55.2
9.6
11
*
E84.0
ICD-10 Finland
Cystic fibrosis with pulmonary manifestations
55.2
9.6
11
*
J01DB01
ATC
cefalexin; oral
1.3
9.6
2362
21846
C08CA02
ATC
felodipine; oral
1.5
9.6
366
2608
XQ800
NOMESCO Finland
Prick test
1.9
9.6
126
690
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
9.6
1085
9138
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.7
9.5
378
5141
N03AX12
ATC
[U] gabapentin; oral
1.4
9.4
433
3194
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.8
9.4
146
841
E0000UV, ,
ATC
1.3
9.4
1114
9430
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
30.1
9.4
12
*
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
9.4
1083
9136
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
8.0
9.3
20
25
R01AD12
ATC
fluticasone furoate; nasal
1.4
9.3
584
4531
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.5
9.3
274
1854
J96.9
ICD-10 Finland
Respiratory failure, unspecified
3.4
9.3
32
94
N05CF01
ATC
zopiclone; oral
1.3
9.3
986
8229
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
3.3
9.3
34
104
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
8.7
9.3
19
22
11
HP
Coronary artery bypass surgery
1.9
9.3
119
647
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
2.3
9.3
71
319
M05BA06
ATC
ibandronic acid; systemic
2.3
9.3
68
300
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
9.3
233
1523
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.6
9.2
120
2100
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
3.8
9.2
27
71
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.5
9.2
334
2359
WPB10
NOMESCO Finland
Making a convalescent care decision
4.2
9.2
24
58
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.5
9.1
55
222
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
1.6
9.1
204
1297
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
1.9
9.0
118
645
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
9.0
438
3259
C08CA05
ATC
nifedipine; systemic
1.6
9.0
224
1460
RK250, ,
NOMESCO Finland
4.2
8.9
23
55
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
8.9
513
3928
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
2.7
8.9
47
178
N05AX08
ATC
risperidone; systemic
0.6
8.8
118
2048
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
8.8
1253
10817
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
2.9
8.8
41
145
L01BB01, ,
ATC
9.5
8.8
17
18
R01AD08
ATC
fluticasone; nasal
1.3
8.7
620
4898
E000001, ,
ATC
1.4
8.7
495
3782
J67.8
ICD-10 Finland
Hypersensitivity pneumonitis due to other organic dusts
50.1
8.7
10
*
D07AC13
ATC
mometasone; topical
1.3
8.7
762
6198
GD1UN
NOMESCO Finland
Lung circulation SPECT
3.4
8.6
30
89
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.4
8.6
417
3102
F03
ICD-10 Finland
Unspecified dementia
0.5
8.6
63
1323
R03AK11
ATC
formoterol and fluticasone; inhalant
2.2
8.6
69
317
J43.1
ICD-10 Finland
Panlobular emphysema
16.3
8.5
13
8
J15.8
ICD-10 Finland
Other bacterial pneumonia
3.1
8.5
35
115
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
2.8
8.5
42
153
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
3.5
8.5
28
80
N06DA03
ATC
rivastigmine; oral, transdermal
0.5
8.5
64
1332
ZYY98
NOMESCO Finland
Missed treatment contact, no notification given by patient
7.3
8.4
19
26
J42
ICD-10 Finland
Unspecified chronic bronchitis
2.6
8.4
47
183
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
2.5
8.4
50
201
L01CB
ATC
Podophyllotoxin derivatives
7.9
8.4
18
23
R05CB13
ATC
dornase alfa (desoxyribonuclease); inhalant
+∞
8.3
8
*
4038, ,
NOMESCO Finland
+∞
8.3
8
*
304
Kela drug reimbursment
Dornase alfa
+∞
8.3
8
*
5169X
ICD-9 Finland
Other alveolar and parietoalveolar pneumopathy, Unspecified alveolar and parietoalveolar pneumopathy
+∞
8.3
8
*
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
3.8
8.3
25
67
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
1.6
8.3
212
1390
J98.4
ICD-10 Finland
Other disorders of lung
8.5
8.3
17
20
3006
Kela drug reimbursment
Baricitinib
10.8
8.3
15
14
ECB20
NOMESCO Finland
Oral alveoplasty
2.8
8.3
39
139
R2110
NOMESCO Finland
Giving the first information
1.7
8.3
141
836
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.6
8.2
214
1410
M01CB03
ATC
auranofin; oral
3.4
8.2
29
87
R04
ICPC
Breathing problem other
1.8
8.2
109
601
J02AC03
ATC
voriconazole; systemic
7.5
8.1
18
24
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
8.1
961
8101
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.8
8.1
40
146
C09AA05
ATC
ramipril; oral
1.3
8.1
925
7765
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
1.8
8.1
124
713
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
2.2
8.1
66
305
C02KX01
ATC
bosentan; oral
33.4
8.1
10
*
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
33.4
8.1
10
*
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
8.1
8.1
17
21
H26.3
ICD-10 Finland
Drug-induced cataract
3.8
8.1
24
64
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
4.0
8.1
22
55
L04AC07
ATC
tocilizumab; parenteral
10.0
8.0
15
15
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
2.6
7.9
45
177
R06.8
ICD-10 Finland
Other and unspecified abnormalities of breathing
2.6
7.9
45
177
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.7
7.8
148
902
D06BB04
ATC
podophyllotoxin; topical
2.3
7.8
58
258
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
2.1
7.8
75
370
293
Kela drug reimbursment
Baricitinib
10.8
7.8
14
13
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
0.7
7.8
232
3335
E66.8
ICD-10 Finland
Other obesity
1.9
7.7
88
461
M06
ICD-10 Finland
Other rheumatoid arthritis
3.7
7.7
24
66
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
7.7
1214
10557
FXE00
NOMESCO Finland
Use of ECLA
45.1
7.7
9
*
J18
ICD-10 Finland
Pneumonia, organism unspecified
2.9
7.6
35
123
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
7.6
638
5146
C61
ICD-10 Finland
Malignant neoplasm of prostate
0.7
7.6
248
3508
R04.0
ICD-10 Finland
Epistaxis
1.5
7.6
272
1916
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
8.0
7.6
16
20
J98.9
ICD-10 Finland
Respiratory disorder, unspecified
8.0
7.6
16
20
B37.0
ICD-10 Finland
Candidal stomatitis
2.9
7.6
34
118
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
11.9
7.6
13
11
L04AA37
ATC
[U] baricitinib
10.0
7.5
14
14
WX723
NOMESCO Finland
CPAP therapy
1.9
7.5
93
501
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
3.3
7.5
27
82
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
3.3
7.5
27
82
R03AC13
ATC
formoterol; inhalant
1.7
7.5
142
867
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
3.9
7.4
21
54
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
2.8
7.4
35
125
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
3.5
7.4
24
68
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
7.4
376
4933
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
1.7
7.4
123
725
ZY000
NOMESCO Finland
Hospital inpatient
3.4
7.4
26
78
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
7.3
316
2304
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.4
7.3
384
2894
2770A
ICD-9 Finland
Other and unspecified disorders of metabolism, Cystic fibrosis
+∞
7.3
7
*
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
1.5
7.3
194
1286
ZX100
NOMESCO Finland
Oral
2.3
7.3
52
228
N06DX01
ATC
memantine; oral
0.7
7.2
180
2682
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
3.9
7.2
20
51
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
3.9
7.2
20
51
B48.5
ICD-10 Finland
Pneumocystosis
30.1
7.1
9
*
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
1.5
7.1
221
1514
ZX121
NOMESCO Finland
Central venous catheter
6.6
7.1
17
26
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.9
7.1
87
468
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
7.1
849
7150
I25.2
ICD-10 Finland
Old myocardial infarction
1.4
7.1
298
2164
XA421
NOMESCO Finland
Nocturnal polygraphy
5.6
7.1
19
34
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
1.8
7.0
101
571
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.5
7.0
217
1485
R03AC12
ATC
salmeterol; inhalant
1.6
6.9
148
932
XG480
NOMESCO Finland
Histamine provocation of respiratroy tract
2.9
6.9
31
108
JN4BD
NOMESCO Finland
Extensive body CT
1.4
6.9
332
2467
A28
ICPC
Limited function/disability NOS
1.3
6.9
723
5993
JN4AD
NOMESCO Finland
Body CT examination
1.4
6.9
374
2834
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.8
1027
8859
B07.9
ICD-10 Finland
Verruca simplex
1.9
6.8
75
390
R03DA04
ATC
theophylline; systemic, rectal
1.5
6.8
191
1283
J17.1*B25.0
ICD-10 Finland
Cytomegaloviral pneumonitis
40.1
6.8
8
*
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
4.3
6.7
17
40
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
2.3
6.7
50
223
N02BE01
ATC
paracetamol; systemic, rectal
1.3
6.7
2659
25304
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
3.4
6.7
23
68
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
3.4
6.7
23
68
RS220, ,
NOMESCO Finland
2.7
6.7
34
127
N06DA02
ATC
donepezil; oral
0.6
6.7
122
1949
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.6
408
3149
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
7.8
6.6
14
18
TGW99
NOMESCO Finland
Other minor procedure in thoracic surgery
5.9
6.6
17
29
J01GB01
ATC
tobramycin; inhalant, parenteral
12.3
6.6
11
9
N07BA03
ATC
varenicline; oral
1.9
6.6
80
430
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
3.5
6.6
22
64
8070/3-C34.3
ICD-O-3
Squamous cell carcinoma, NOS, of lower lobe, lung
3.3
6.5
24
74
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
8.7
6.5
13
15
ZXE10
NOMESCO Finland
More than one and less than three hours
1.2
6.5
1010
8735
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.7
6.5
111
661
J98.6
ICD-10 Finland
Disorders of diaphragm
3.7
6.5
20
55
S22.2
ICD-10 Finland
Fracture of sternum
3.1
6.4
25
80
J99.1*M32.1
ICD-10 Finland
Respiratory disorders in systemic: lupus erythematosus
70.0
6.4
7
*
G73.7*M34.8
ICD-10 Finland
Myopathy in scleroderma
70.0
6.4
7
*
L04AA17
ATC
[U] adalimumab
7.4
6.4
14
19
R4130
NOMESCO Finland
Speech therapy
1.9
6.4
79
427
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
3.0
6.4
27
91
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
1.8
6.4
83
456
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.5
6.4
61
1166
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
6.4
841
7146
OAB48
NOMESCO Finland
Lifestyle advice and guidance
3.7
6.4
19
51
A10AB05
ATC
insulin aspart; parenteral
1.4
6.4
230
1625
R06AX22
ATC
ebastine; oral
1.4
6.3
319
2387
WW200, ,
SPAT
0.8
6.3
545
6660
XG467
NOMESCO Finland
Nocturnal CO2 monitoring
9.3
6.3
12
13
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
9.3
6.3
12
13
E000002, ,
ATC
1.4
6.3
228
1612
L95
ICPC
Osteoporosis
1.7
6.2
114
692
EBA10
NOMESCO Finland
Operative extraction of tooth
1.5
6.2
211
1473
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.5
6.2
199
1375
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
6.2
838
7138
1240
FHL
Bronchoscopy
2.3
6.2
43
187
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
6.2
580
4738
J05AB11
ATC
valaciclovir; oral
1.3
6.2
348
2652
R79
ICPC
Chronic bronchitis
5.7
6.1
16
28
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.4
6.1
305
2278
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
3.0
6.1
26
88
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.1
541
4387
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
1.5
6.1
183
1247
L04AB06
ATC
golimumab; parenteral
4.1
6.1
16
39
NCB20
NOMESCO Finland
Primary total prosthetic replacement of elbow joint
12.5
6.1
10
8
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
6.1
184
1256
RK310, ,
NOMESCO Finland
8.6
6.0
12
14
-1, ,
NOMESCO Finland
1.3
6.0
684
5711
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
10.0
6.0
11
11
I20.09
ICD-10 Finland
Unstable angina
1.4
6.0
216
1524

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1202
3944
4.25
322.83
1.4
1.3
65.62
34.74
iu/ml
4.71
418
1175
575
1004
6.75
307.65
1.3
1.2
—
—
—
0
0
392
406
10.84
307.65
3.0
2.4
—
—
—
0
0
685
1171
7.15
307.65
1.4
1.6
12.84
17.39
iu/ml
—
9
33
320
96
36.87
307.65
1.1
1.1
—
—
—
0
0
1281
2942
6.54
307.65
1.5
1.3
593.66
495.71
titre
0.98
423
662
476
746
7.31
297.32
1.3
1.2
1.02
0.52
u/ml
0.47
46
61
505
865
6.73
289.59
2.0
1.6
6.01
7.52
iu/ml
0.55
116
200
1098
3676
4.00
281.37
1.3
1.3
29.18
13.50
u/ml
1.68
305
1263
1163
4194
3.76
264.98
9.1
7.2
5.05
5.08
kpa
0.32
1120
4014
1162
4194
3.76
264.31
9.1
7.2
9.87
11.88
kpa
52.85
1121
4017
369
500
8.20
261.37
1.3
1.2
25.89
2.18
u/ml
1.82
39
33
754
2015
4.57
260.64
3.5
1.5
—
—
—
0
0
1152
4167
3.74
260.64
9.1
7.1
1.71
0.91
mmol/l
9.05
986
3376
1152
4183
3.72
258.87
9.1
7.2
7.43
7.41
ph
7.83
796
2306
387
589
7.33
247.04
1.4
1.2
3.42
3.28
u/ml
0.04
54
53
303
346
9.56
246.12
3.2
1.3
—
—
—
0
0
303
346
9.56
246.12
3.2
1.3
—
—
—
0
0
303
346
9.56
246.12
3.2
1.3
—
—
—
0
0
303
346
9.56
246.12
3.2
1.3
—
—
—
0
0
394
619
7.11
244.14
1.3
1.2
40.63
36.74
u/ml
0.06
17
27
385
590
7.27
244.14
1.3
1.2
9.17
5.37
u/ml
0.56
80
88
453
852
6.02
234.56
2.6
2.3
130.71
126.96
g/l
1.40
198
686
433
785
6.21
232.86
1.7
1.4
12.86
15.69
iu/ml
0.14
22
14
1889
9806
3.22
229.25
12.6
5.8
—
—
—
0
0
2338
13953
3.42
219.31
13.0
5.7
0.69
0.63
e9/l
15.00
2164
11661
2340
14007
3.41
217.62
13.0
5.7
0.04
0.04
e9/l
4.69
2165
11720
242
242
10.73
216.26
1.2
1.1
41.00
49.25
u/ml
—
10
16
2372
14386
3.41
214.20
13.8
5.9
0.22
0.20
e9/l
7.65
2215
12221
682
1941
4.18
213.82
4.4
2.8
10.58
10.83
g/l
0.60
652
1772
2343
14232
3.33
208.32
13.2
5.8
1.89
1.83
e9/l
1.11
2192
12216
2209
13018
3.18
206.07
13.7
6.0
2.80
2.86
%
0.61
2173
12048
2211
13042
3.18
205.80
13.8
6.2
8.96
9.25
%
5.06
2172
12071
2207
13010
3.18
205.56
13.8
6.1
0.61
0.65
%
2.31
2170
12038
2183
12902
3.12
200.10
13.3
6.0
60.72
59.02
%
8.84
2155
12189
2212
13183
3.13
199.47
13.8
6.1
24.10
25.36
%
6.39
2176
12356
140
59
24.75
197.29
1.1
1.1
—
—
—
0
0
140
59
24.75
197.29
1.1
1.1
—
—
—
0
0
140
59
24.75
197.29
1.1
1.1
—
—
—
0
0
958
3810
3.15
176.23
10.0
7.4
93.26
95.24
%
12.89
926
3672
244
325
8.04
174.13
1.2
1.1
40.09
3.33
u/ml
—
11
9
310
558
6.04
166.51
1.3
1.3
73.85
161.54
titre
0.70
13
13
310
563
5.98
164.94
1.3
1.3
269.12
282.98
titre
0.04
34
47
275
453
6.54
161.42
1.4
1.3
7.79
10.05
u/ml
—
14
8
529
1545
3.90
156.97
2.3
2.0
1.07
1.46
g/l
3.79
496
1393
270
449
6.47
156.94
3.0
2.6
—
—
—
0
0
111
47
24.42
155.90
4.2
4.4
—
—
—
0
0
197
237
8.78
152.67
1.3
1.2
50.44
71.66
u/ml
0.31
15
11
638
2168
3.42
150.14
11.2
8.8
24.92
24.17
mmol/l
6.68
614
2114
2355
15757
2.80
149.17
15.8
9.0
4.95
4.39
e9/l
21.40
2194
13463
305
640
5.16
137.97
1.8
1.4
0.22
0.24
g/l
1.88
295
608
308
667
5.00
134.20
1.8
1.5
1.19
1.16
g/l
0.95
300
632
204
304
7.09
131.34
1.3
1.2
—
—
—
0
0
239
431
5.91
127.53
1.4
1.3
—
—
—
0
0
232
414
5.96
125.13
1.4
1.2
58.70
48.59
u/ml
0.28
31
37
218
373
6.19
122.72
1.3
1.4
150.24
157.43
au/ml
0.29
59
112
234
429
5.80
122.64
1.3
1.3
46.00
16.45
u/ml
—
7
9
180
255
7.41
121.24
1.3
1.2
—
—
—
0
0
91
44
21.25
121.02
1.0
1.0
—
—
—
0
0
91
44
21.25
121.02
1.0
1.1
—
—
—
0
0
283
630
4.83
119.01
1.5
1.9
11.14
13.71
mg/l
2.28
261
574
177
258
7.20
116.15
1.3
1.2
118.49
112.17
%
1.42
171
233
1654
10104
2.30
115.36
5.5
4.5
—
—
—
0
0
594
2247
3.01
114.38
7.1
6.5
25.16
24.34
mmol/l
5.01
577
2149
791
3484
2.68
114.22
11.4
7.9
126.01
119.68
g/l
13.27
776
3404
413
1267
3.59
112.21
1.6
1.3
235.79
259.66
u/ml
0.20
384
1161
93
57
16.77
110.85
3.4
1.2
—
—
—
0
0
742
3210
2.70
110.68
2.9
1.4
—
—
—
0
0
1797
11495
2.26
110.41
4.7
3.5
1639.44
1910.41
ng/l
1.96
1666
10124
606
2370
2.91
109.52
6.9
3.8
5.24
5.14
kpa
1.91
594
2243
90
54
17.11
108.41
1.3
1.6
2880.00
3840.00
titre
—
5
10
591
2308
2.91
106.90
6.9
3.8
7.42
7.41
ph
4.52
522
1925
178
286
6.53
106.50
1.2
1.2
5.55
5.53
u/ml
0.00
111
134
115
110
10.80
105.38
4.0
1.9
32.51
58.93
ug/l
3.16
115
105
151
206
7.64
105.03
1.2
1.2
97.60
93.65
%
0.88
146
191
1441
8580
2.22
103.65
6.2
3.1
31.57
40.10
u/l
3.00
1392
8053
2212
15669
2.29
102.56
12.2
6.6
11.48
12.89
umol/l
6.35
2170
14938
106
94
11.62
102.16
50.3
25.1
169.29
105.72
ug/l
9.17
85
76
145
199
7.58
100.30
1.2
1.1
77.35
74.32
u/ml
—
12
5
93
73
13.09
96.71
48.7
36.2
8.37
6.68
ug/l
8.12
82
66
145
212
7.11
94.75
2.5
2.2
16.69
15.91
%
1.53
145
212
141
201
7.29
94.27
1.5
1.2
0.52
0.40
g/l
2.41
104
150
141
201
7.29
94.27
1.5
1.2
7.71
6.83
g/l
1.24
100
149
141
201
7.29
94.27
1.5
1.2
3.14
2.94
g/l
0.53
104
151
140
201
7.23
92.99
1.5
1.2
—
—
—
0
0
389
1301
3.26
91.43
5.1
2.9
25.73
24.70
mmol/l
4.67
381
1280
621
2688
2.62
90.85
6.9
4.0
0.79
0.94
%
0.93
273
889
596
2542
2.65
89.76
6.5
4.0
0.54
0.78
%
2.28
262
838
308
900
3.68
89.38
5.4
2.9
7.55
7.81
kpa
2.12
302
877
285
794
3.84
88.66
5.0
2.8
87.71
88.68
%
1.30
279
771
604
2622
2.60
87.57
1.5
1.6
—
—
—
0
0
129
183
7.30
86.58
1.1
1.1
—
—
—
0
0
438
1634
2.94
84.95
2.3
1.8
1.28
2.33
ug/l
1.46
397
1415
176
352
5.23
83.50
1.7
1.6
0.93
0.90
g/l
0.08
133
280
275
784
3.74
82.61
5.9
4.0
—
—
—
0
0
133
207
6.66
81.91
2.2
2.3
—
—
—
0
0
1042
5888
2.13
81.06
2.5
1.7
1.74
1.60
mg/l
0.39
869
4666
124
185
6.93
79.46
2.2
2.3
29.09
30.11
iu/ml
0.04
13
34
122
179
7.04
79.39
1.1
1.2
—
—
—
0
0
195
446
4.59
78.84
4.2
3.0
4.90
4.48
e9/l
1.44
195
446
572
2569
2.49
76.37
7.0
4.1
0.08
0.12
%
0.80
222
774
378
1377
2.98
76.17
1.4
1.3
—
—
—
0
0
570
2565
2.48
75.74
7.0
4.2
0.04
0.14
%
2.47
221
729
962
5389
2.12
75.63
9.7
4.6
—
—
—
0
0
269
801
3.57
75.59
3.2
2.3
3.89
3.62
g/l
2.03
261
758
1986
14373
1.98
75.01
10.5
6.8
1.20
1.21
mmol/l
3.63
1893
13175
166
350
4.94
74.03
1.2
1.2
339.33
278.27
u/ml
1.12
115
194
207
533
4.08
71.64
4.3
3.1
60.15
59.66
%
0.20
207
533
107
153
7.20
71.25
1.3
1.1
—
—
—
0
0
650
3186
2.30
70.78
4.7
3.2
220.34
257.40
ng/l
1.30
616
2937
1449
9637
1.91
68.11
5.6
4.3
7.40
7.40
ph
2.28
1128
7104
246
741
3.51
67.78
3.9
2.6
15.88
15.95
%
0.11
241
726
100
141
7.29
67.42
1.3
1.1
—
—
—
0
0
69
60
11.73
67.23
1.1
1.4
26.62
28.82
s
2.04
69
60
75
74
10.35
67.13
3.5
1.4
—
—
—
0
0
2488
19870
2.08
66.47
10.8
4.4
19.17
14.48
mm/h
32.74
2426
18298
474
2118
2.45
63.17
1.5
1.5
—
—
—
0
0
2101
16007
1.89
62.13
11.5
7.6
1.20
1.21
mmol/l
2.13
1854
13735
462
2062
2.45
61.64
15.8
9.3
16.32
15.77
%
4.20
443
1988
182
477
3.98
61.38
1.2
1.2
—
—
—
0
0
800
4487
2.04
60.64
2.9
2.1
—
—
—
0
0
781
4384
2.03
58.82
2.1
1.5
2.98
2.74
g/l
1.87
571
2481
502
2389
2.30
57.65
1.5
1.5
—
—
—
0
0
112
209
5.51
57.27
1.7
2.0
1039.69
1096.97
e6/l
0.23
100
188
275
982
2.97
56.93
3.5
1.9
21.46
21.42
s
0.02
255
899
95
154
6.32
56.18
1.7
2.1
71.83
72.25
%
0.08
90
142
1634
11772
1.78
55.31
22.7
12.7
0.00
0.00
e9/l
0.71
1415
9488
467
2192
2.32
55.24
15.1
7.6
25.44
24.78
mmol/l
2.65
462
2174
376
1613
2.51
54.32
7.5
4.0
—
—
—
0
0
630
3382
2.07
53.02
12.7
6.8
10.22
11.60
mmol/l
5.35
600
3222
886
5391
1.89
51.64
8.9
3.0
0.80
0.82
mmol/l
3.82
831
5030
116
245
4.87
51.55
1.3
1.1
—
—
—
0
0
52
44
11.99
51.49
1.1
1.1
—
—
—
0
0
202
690
3.06
45.05
8.3
4.8
3.08
2.75
mmol/l
0.83
158
463
264
1045
2.66
44.76
7.0
5.8
1.43
1.37
mmol/l
0.40
242
931
995
6504
1.76
44.65
5.3
4.4
581.57
542.11
ng/l
0.09
909
5740
366
1690
2.31
44.50
5.0
5.0
1.78
1.57
%
4.69
350
1600
2543
21497
1.85
43.95
16.7
8.5
78.53
83.27
u/l
5.36
2501
20277
1834
14182
1.67
43.66
6.5
5.1
33.20
34.50
g/l
17.83
1721
13191
470
2418
2.10
43.64
2.0
2.2
358.61
383.67
nmol/l
1.06
445
2198
62
85
7.42
42.83
1.8
2.0
—
—
—
0
0
120
309
3.99
41.41
1.2
1.2
223.46
189.55
miu/ml
0.27
13
85
80
150
5.44
40.70
1.6
1.3
0.77
2.57
u/ml
0.98
54
86
106
252
4.31
40.69
1.3
1.5
—
1410.00
—
0
8
61
90
6.89
39.45
1.1
1.2
1.04
1.08
ratio
1.63
53
72
1344
9853
1.62
37.46
4.3
2.2
134.69
230.32
u/l
6.61
1267
9265
960
6497
1.68
36.53
4.3
3.2
533.56
538.60
mosm/kgh2o
0.36
886
5723
565
3304
1.86
35.68
3.8
3.3
4.76
4.98
e9/l
0.31
516
2708
1192
8560
1.62
35.68
5.3
3.6
0.52
295.31
estimate
—
5
52
1957
15808
1.60
35.55
19.9
20.5
1.36
1.38
inr
1.08
1726
13399
1170
8380
1.62
35.31
10.3
6.5
—
—
—
0
0
540
3128
1.87
35.09
2.1
2.1
0.21
0.20
g/l
3.81
507
2888
555
3246
1.86
34.98
12.8
6.9
1.40
1.39
mmol/l
0.14
535
3182
50
68
7.45
34.78
1.1
1.1
4.50
9.13
u/ml
—
8
8
2148
17803
1.61
34.47
10.0
5.4
6.85
6.93
mmol/l
1.04
2073
17022
534
3106
1.86
34.18
14.2
8.1
—
—
—
0
0
318
1549
2.17
33.62
5.5
5.1
0.87
0.86
%
0.12
302
1466
71
143
5.05
33.37
1.6
2.0
428.54
532.79
e6/l
0.58
56
121
38
40
9.60
32.40
1.2
1.1
—
—
—
0
0
70
144
4.95
32.11
1.7
2.1
216.88
226.74
e6/l
0.10
60
129
328
1645
2.11
32.11
5.2
4.3
36.94
36.90
°c
1.87
322
1621
1234
9118
1.57
31.75
5.4
3.6
0.44
0.50
e6/l
0.59
1002
6957
53
86
6.25
31.33
1.6
2.1
29.42
32.01
%
0.48
53
86
184
727
2.62
31.17
6.4
6.8
11.68
11.35
mmol/l
0.69
168
651
184
727
2.62
31.17
6.4
6.8
103.88
105.11
mmol/l
3.25
168
651
45
63
7.23
30.52
1.4
1.5
—
—
—
0
0
417
2357
1.88
28.88
16.3
8.8
1.37
1.28
%
1.74
411
2341
697
4573
1.67
28.80
7.7
5.8
1.04
1.04
mmol/l
0.20
649
4243
405
2275
1.89
28.58
16.7
9.0
0.61
0.63
%
0.40
399
2260
1378
10611
1.52
28.45
5.6
3.8
40.45
100.23
e6/l
3.12
1143
8365
1043
7573
1.56
28.16
4.1
2.9
4.72
4.45
e6/l
0.22
973
6928
248
1176
2.20
27.93
4.3
3.6
1.39
1.45
mmol/l
0.45
243
1155
1472
11527
1.51
27.84
6.9
4.4
152.82
114.38
e6/l
0.42
1163
8579
576
3656
1.70
26.77
4.4
3.6
2.29
1.76
mmol/l
2.31
498
3136
595
3810
1.69
26.76
4.4
3.7
7.38
7.38
ph
1.22
365
2289
763
5207
1.61
26.67
2.6
2.7
21.18
21.73
%
0.49
723
4812
844
5909
1.58
26.43
2.7
2.7
11.51
12.02
umol/l
1.43
795
5471
804
5578
1.59
26.14
2.6
2.7
2.23
2.23
g/l
0.04
751
5118
585
3758
1.68
25.91
4.4
3.6
5.88
5.80
kpa
0.89
566
3656
253
1249
2.11
25.68
8.3
4.1
25.20
24.72
mmol/l
1.90
241
1123
1007
7415
1.52
24.81
6.8
4.3
83.46
82.30
%
0.74
992
7262
1068
7966
1.51
24.73
6.0
3.0
366.97
364.72
umol/l
0.27
947
6803
515
3243
1.70
24.47
2.0
2.5
66.44
65.81
g/l
1.02
474
2939
1536
12434
1.45
22.89
5.7
4.6
148.54
99.60
ng/l
0.18
1297
10013
1342
10633
1.45
22.21
4.4
3.5
2.34
2.35
mmol/l
0.78
1236
9519
742
5229
1.54
21.95
2.8
2.0
29.82
30.06
s
0.51
722
5068
34
51
6.73
21.67
1.0
1.1
—
—
—
0
0
520
3381
1.64
21.64
2.5
2.7
9.98
10.05
umol/l
0.02
456
3030
41
76
5.45
21.18
1.1
1.2
—
—
—
0
0
2185
19087
1.44
20.30
7.1
5.4
347.22
1791.92
e6/l
2.23
37
350
247
1331
1.93
19.57
4.2
2.1
292.29
513.84
ug/l
2.44
237
1264
737
5308
1.50
19.36
4.9
3.5
1.48
1.77
e6/l
0.80
424
2810
1488
12231
1.40
19.03
3.2
2.4
76.79
79.25
nmol/l
2.97
1372
10659
1725
14616
1.38
17.99
5.6
4.3
0.00
0.00
estimate
1.08
464
3200
1179
9379
1.40
17.95
3.0
2.7
61.08
69.90
u/l
0.50
1107
8649
29
19
15.38
17.94
1.7
1.6
—
—
—
0
0
1743
14808
1.38
17.80
5.6
4.3
7.95
4.26
estimate
0.35
475
3299
2235
19815
1.41
17.54
42.0
25.4
14.40
13.96
%
35.44
2227
19527
355
2222
1.67
16.92
5.6
4.4
—
—
—
0
0
1745
14911
1.37
16.73
5.7
4.3
0.01
0.11
estimate
0.54
440
3057
59
176
3.40
16.55
1.1
1.2
99.09
122.41
titre
0.19
11
29
59
176
3.40
16.55
1.1
1.2
104.00
98.00
titre
—
5
5
398
2581
1.62
16.47
4.3
4.1
1.21
1.22
mmol/l
1.70
364
2232
34
68
5.04
16.19
1.0
1.0
—
—
—
0
0
98
394
2.53
16.11
2.3
3.1
10.61
10.61
mmol/l
0.00
98
388
101
418
2.46
15.62
3.9
2.3
0.95
0.13
mmol/l
1.20
95
399
161
810
2.04
15.53
1.4
1.4
—
—
—
0
0
24
36
6.71
15.30
1.5
2.1
2.01
0.20
e9/l
—
11
8
639
4675
1.46
15.04
2.9
2.4
1.86
1.76
%
1.75
554
4116
130
611
2.17
14.99
3.9
4.0
1.40
1.63
%
0.24
121
533
52
155
3.39
14.64
2.0
2.6
40.48
36.28
%
0.79
31
91
119
549
2.21
14.38
1.3
1.2
—
—
—
0
0
168
884
1.95
14.29
3.9
3.5
2.67
1.83
index
0.90
99
469
453
3135
1.52
13.98
3.8
3.1
4.45
4.42
kpa
0.09
435
3042
515
3666
1.48
13.85
2.7
2.4
69.36
67.38
e9/l
0.61
352
2744
283
1759
1.67
13.80
4.5
3.4
25.63
25.00
mmol/l
1.91
268
1704
749
5738
1.40
13.46
4.5
3.4
0.83
1.18
e6/l
2.92
444
3231
538
3898
1.46
13.17
1.3
1.3
—
—
—
0
0
1390
11776
1.32
12.70
4.6
3.8
6.29
6.27
ph
0.27
711
6393
1094
8961
1.33
12.68
2.6
2.4
3.05
2.96
mg/l
0.65
962
7660
120
594
2.06
12.15
1.5
1.5
—
1.00
—
0
5
80
335
2.42
12.14
1.1
1.1
1.62
1.56
g/l
0.71
69
306
225
1366
1.70
11.98
2.5
3.4
67.81
57.84
mg/l
0.52
181
1176
224
1363
1.69
11.83
2.5
3.4
37.82
66.38
mg/l
1.66
179
1178
62
238
2.64
11.29
1.8
2.0
8.46
8.35
mmol/l
0.07
62
238
904
7304
1.33
11.23
4.6
3.4
0.01
0.06
1.34
20
274
203
1231
1.69
10.87
2.4
3.3
2.39
3.34
ratio
0.78
114
760
917
7465
1.32
10.71
5.4
3.9
0.23
0.04
estimate
0.65
382
2469
58
222
2.64
10.65
1.5
1.2
—
—
—
0
0
485
3580
1.42
10.57
2.1
1.9
—
—
—
0
0
336
2314
1.50
10.51
4.2
3.1
128.17
126.84
g/l
0.51
325
2248
53
198
2.70
10.21
2.4
2.8
7.38
7.05
mmol/l
0.44
46
131
1399
12096
1.28
10.15
3.4
3.1
179.66
161.18
ug/l
1.52
1289
11020
151
859
1.79
10.14
1.4
1.5
—
—
—
0
0
227
1461
1.60
9.63
2.1
2.4
3.09
2.92
g/l
1.90
210
1303
77
355
2.20
9.44
1.5
1.5
55.86
64.07
%
0.91
43
221
90
442
2.07
9.39
9.2
22.7
7.96
7.46
mmol/l
0.48
77
370
120
656
1.86
9.19
1.2
1.1
135.38
96.53
titre
0.36
13
49
17
17
10.05
9.01
1.0
1.1
—
—
—
0
0
239
1585
1.55
8.91
2.0
2.4
4.08
3.71
g/l
2.51
221
1427
239
1587
1.55
8.86
2.0
2.4
4.18
4.15
g/l
0.22
223
1430
239
1587
1.55
8.86
2.0
2.4
8.06
7.38
g/l
6.92
222
1427
54
220
2.48
8.79
1.3
1.3
—
—
—
0
0
85
425
2.03
8.48
1.2
1.1
—
—
—
0
0
212
1384
1.57
8.48
2.1
2.4
10.72
10.39
g/l
0.55
194
1207
2658
25156
1.31
7.99
37.8
20.6
26.60
28.93
mg/l
3.96
2541
21623
82
414
2.01
7.99
4.3
3.9
57.44
58.10
%
0.10
75
350
85
435
1.98
7.97
1.6
1.7
4.21
4.41
mmol/24h
0.26
79
373
1006
8542
1.26
7.97
5.5
4.4
0.00
0.00
estimate
1.15
416
2820
1718
15503
1.23
7.67
5.0
3.4
65.80
57.83
u/l
1.65
1619
14189
93
498
1.89
7.65
7.1
6.3
11.85
12.73
mg/l
1.14
87
460
1246
10873
1.24
7.64
5.5
4.4
1.24
0.23
estimate
0.37
404
2640
58
264
2.22
7.41
1.7
1.3
43.15
23.79
%
2.87
29
161
11
7
15.77
7.22
1.0
1.0
33.82
35.70
s
—
11
7
35
127
2.78
7.22
1.5
1.3
5.29
3.26
%
—
7
27
346
2572
1.39
7.16
1.4
1.4
—
—
—
0
0
1152
10030
1.23
7.07
4.0
3.6
—
—
—
0
0
122
734
1.69
6.83
2.0
2.4
30.90
34.46
umol/l
0.74
115
637
113
670
1.71
6.69
1.1
1.2
1192.00
1241.00
titre
—
5
20
25
80
3.14
6.43
1.3
1.6
—
—
—
0
0
265
1921
1.41
6.36
1.9
1.7
1.61
1.53
g/l
0.75
220
1640
111
666
1.69
6.31
1.4
1.3
68.54
60.76
mmol/l
1.28
101
528
35
139
2.53
6.10
8.4
5.6
64.32
62.55
mg/l
0.07
28
94
600
4933
1.27
6.04
1.3
1.3
1.23
1.76
u/ml
1.32
151
1202
14
21
6.69
6.03
1.1
1.0
—
—
—
0
0
410
3215
1.32
5.96
2.6
2.5
14.07
7.25
ug/l
6.31
364
2755
17
34
5.02
5.86
1.5
1.2
118.86
161.69
ng/l
—
10
21
262
1923
1.39
5.86
3.4
2.6
0.65
0.61
%
0.93
262
1914
82
464
1.79
5.76
1.6
1.4
—
—
—
0
0
134
869
1.57
5.62
2.5
2.7
1.82
1.82
mg/l
0.01
120
761
86
503
1.73
5.41
1.6
1.5
—
—
—
0
0
68
374
1.84
5.27
4.6
4.4
—
—
—
0
0
126
823
1.55
5.15
1.7
1.6
16946.70
15491.24
e6/l
0.09
89
575
770
6612
1.22
5.11
1.8
1.8
1105.82
1152.32
nmol/l
0.72
590
4954
8
6
13.36
5.08
3.3
12.2
111.50
101.17
g/l
—
8
6
78
455
1.73
4.98
1.6
1.4
6.04
6.44
mmol/l
0.54
70
433
892
10121
0.84
4.83
2.1
1.9
1.37
1.28
mmol/l
2.79
735
8302
174
1233
1.43
4.79
1.4
1.3
—
—
—
0
0
98
617
1.61
4.71
2.3
2.1
0.90
0.87
%
0.16
66
435
22
79
2.80
4.71
4.8
8.1
6.20
6.00
kpa
0.21
17
69
105
673
1.58
4.69
1.6
1.5
33.70
30.71
g/l
1.73
93
602
29
122
2.39
4.56
1.1
1.1
1.04
2.31
u/ml
0.70
16
52
21
75
2.81
4.55
4.0
1.5
1.88
1.80
umol/l
0.18
21
67
63
356
1.78
4.52
1.0
1.1
—
—
—
0
0
346
2761
1.28
4.42
2.5
2.5
34.62
39.80
u/l
1.16
308
2291
230
1739
1.35
4.33
2.4
2.5
—
—
—
0
0
91
580
1.59
4.20
1.6
1.4
6072.77
2991.11
e6/l
0.34
66
413
762
6650
1.19
4.16
2.7
3.1
2.48
2.46
mmol/l
6.51
690
5930
79
488
1.63
4.14
1.7
1.6
—
—
—
0
0
55
307
1.81
4.14
5.8
3.4
14.40
11.17
index
1.42
42
166
38
724
0.52
4.05
1.3
1.4
—
—
—
0
0
634
7309
0.84
3.98
3.6
3.7
—
—
—
0
0
59
350
1.70
3.65
1.2
1.1
—
—
—
0
0
19
73
2.61
3.63
1.1
1.0
8.23
2.32
u/ml
—
6
10
125
882
1.43
3.61
1.3
1.5
254.74
268.93
ug/g
0.33
78
549
778
6879
1.17
3.58
1.8
1.8
35047202.38
23561577.73
pmol/l
0.23
642
5560
42
227
1.86
3.55
1.1
1.1
0.84
1.69
u/ml
0.83
26
127
297
3652
0.79
3.51
5.1
5.4
32.96
33.42
%
0.30
220
2288
80
518
1.56
3.51
1.7
1.4
200482.96
60869.24
e6/l
0.98
49
306
744
6570
1.17
3.47
5.4
4.6
1.02
1.02
kg/l
0.22
563
4553
78
1178
0.65
3.44
2.1
2.1
3.44
3.40
ratio
0.10
67
965
48
809
0.59
3.39
2.1
1.9
3.35
3.31
mmol/l
0.06
36
603
11
27
4.08
3.39
1.2
2.8
—
18.50
—
0
5
324
2651
1.25
3.39
2.0
2.1
155.58
166.84
ug/g
0.27
258
2086
1007
11065
0.87
3.33
4.4
5.1
22.64
22.32
%
0.24
451
6072
27
128
2.12
3.29
1.1
1.0
4.03
1.16
u/ml
0.51
18
59
225
1769
1.29
3.28
1.2
1.2
—
—
—
0
0
24
110
2.19
3.18
4.3
3.9
56.79
55.03
%
0.14
24
105
92
629
1.48
3.17
1.5
1.5
—
—
—
0
0
76
503
1.52
3.06
1.1
1.1
22.80
12.47
eliau/ml
—
5
35
6
8
7.51
3.05
1.2
1.0
0.08
0.08
—
6
8
711
7967
0.86
3.05
3.2
3.6
0.70
0.84
ug/l
3.07
521
5823
10
26
3.85
2.98
1.5
1.1
—
—
—
0
0
10
26
3.85
2.98
1.5
1.1
—
—
—
0
0
10
26
3.85
2.98
1.5
1.1
—
—
—
0
0
17
69
2.47
2.95
3.5
8.6
5.48
5.49
kpa
0.00
17
69
24
114
2.11
2.94
1.1
1.0
0.39
0.46
u/ml
0.07
12
43
22
102
2.16
2.86
1.4
1.3
29.68
22.59
%
0.48
16
83
11
290
0.38
2.85
1.3
1.2
1.52
1.52
g/l
0.03
11
290
34
186
1.84
2.83
1.1
1.1
5.08
2.89
u/ml
0.25
17
87
31
167
1.86
2.71
1.6
1.6
1.83
2.81
u/field
0.40
23
118
19
85
2.24
2.70
1.3
1.1
1.53
1.53
mmol/l
0.00
11
55
29
154
1.89
2.65
1.1
1.1
1.35
0.93
u/ml
0.16
18
80
1177
10901
1.13
2.65
4.5
4.2
11.21
9.27
mg/mmol
0.73
769
6985
33
183
1.81
2.65
1.1
1.1
1.47
0.93
u/ml
0.27
18
77
17
74
2.30
2.57
1.2
1.1
—
—
—
0
0
2597
25226
1.15
2.54
28.8
18.7
—
—
—
0
0
53
339
1.57
2.54
1.2
1.3
272.22
275.30
mosm/kgh2o
0.40
46
238
47
295
1.60
2.45
1.3
1.3
—
—
—
0
0
7
17
4.12
2.36
1.6
1.1
—
—
—
0
0
95
696
1.38
2.33
1.3
1.2
—
—
—
0
0
42
264
1.60
2.20
1.3
1.2
—
—
—
0
0
61
420
1.46
2.13
1.3
1.2
—
—
—
0
0
8
25
3.21
2.09
2.5
5.4
54.63
61.35
ug/min
—
8
20
117
905
1.30
2.04
2.8
2.7
62.11
58.72
%
0.87
112
871
36
223
1.62
2.02
3.1
2.8
29.83
30.96
mg/l
0.08
30
173
47
311
1.52
2.00
1.6
1.3
96291.84
124889.17
e6/l
0.13
32
212
161
1300
1.25
2.00
2.9
3.3
4.20
4.33
pmol/l
0.63
144
1128
57
395
1.45
1.95
1.4
1.2
—
—
—
0
0
17
84
2.03
1.95
1.1
1.1
1558.12
1558.51
miu/ml
0.00
17
84
6
16
3.75
1.93
1.5
1.1
—
—
—
0
0
39
252
1.55
1.86
1.4
1.3
7.33
7.41
ph
1.40
28
178
20
107
1.87
1.86
1.3
1.2
32.96
40.74
g/l
—
8
46
24
137
1.76
1.83
1.3
1.7
9047.63
2774.71
u/l
—
9
38
33
209
1.58
1.73
1.2
1.1
—
—
—
0
0
300
2610
1.16
1.73
4.0
3.8
91.26
99.25
ng/l
0.98
266
2205
20
110
1.82
1.72
5.0
7.7
24.71
24.72
mmol/l
0.00
15
100
122
974
1.26
1.71
3.1
3.3
0.85
0.83
nmol/l
0.23
97
769
35
226
1.55
1.70
1.4
1.5
—
—
—
0
0
40
267
1.50
1.68
1.0
1.1
—
—
—
0
0
27
164
1.65
1.68
2.1
1.5
—
—
—
0
0
10
41
2.44
1.64
2.1
1.3
49.70
49.20
umol/l
—
10
41
1140
10756
1.09
1.63
3.7
3.5
7.23
7.24
mmol/l
0.03
955
8892
1126
10627
1.09
1.59
3.7
3.5
63.70
50.12
mg/l
1.21
780
7042
35
230
1.53
1.59
1.5
1.2
105.51
97.15
pmol/l
0.51
35
230
29
448
0.64
1.58
1.3
1.3
—
—
—
0
0
1396
13301
1.09
1.58
3.5
3.0
—
—
estimate
—
0
0
32
207
1.55
1.56
1.7
1.5
1948.09
1814.63
ml
0.48
32
201
29
184
1.58
1.54
1.6
2.0
507.39
495.61
min
0.28
18
127
7
27
2.60
1.51
2.3
1.3
0.17
0.94
%
—
7
17
32
209
1.54
1.51
1.2
1.1
—
—
—
0
0
69
902
0.76
1.47
3.7
3.9
95.65
100.11
u/ml
0.04
69
871
62
462
1.35
1.47
2.0
2.2
0.90
1.23
g/24h
0.61
43
269
19
109
1.75
1.46
1.4
1.2
—
—
—
0
0
24
148
1.63
1.44
1.3
1.3
161.48
392.24
ug/l
—
10
73
61
456
1.34
1.43
2.5
2.2
31.95
24.02
mg/l
0.41
26
150
52
379
1.38
1.42
1.1
1.1
—
—
—
0
0
20
119
1.68
1.37
1.1
1.0
—
—
—
0
0
49
665
0.73
1.37
1.0
1.1
—
—
—
0
0
18
104
1.73
1.36
4.7
1.3
25.50
28.36
umol/l
0.55
18
97
51
374
1.37
1.36
1.7
2.1
—
—
—
0
0
77
974
0.79
1.31
1.1
1.2
—
—
—
0
0
6
24
2.50
1.30
1.0
1.0
19.15
32.99
iu/ml
—
6
24
24
367
0.65
1.29
2.5
3.5
4.83
6.60
nmol/l
0.57
24
362
5
18
2.78
1.28
2.0
1.5
—
—
—
0
0
2339
23907
0.92
1.28
5.3
5.4
1.38
1.41
mmol/l
2.43
2090
21554
2670
26241
1.10
1.28
41.3
25.5
138.83
139.58
mmol/l
34.35
2640
25695
60
457
1.32
1.27
3.8
2.6
1.20
1.19
mmol/l
0.12
60
452
81
643
1.27
1.26
1.1
1.3
48.45
41.45
u/l
0.10
74
542
61
467
1.31
1.25
3.8
2.5
4.21
4.12
mmol/l
0.77
61
462
61
467
1.31
1.25
3.8
2.5
105.30
105.53
mmol/l
0.14
61
462
5
19
2.63
1.21
1.0
1.0
—
—
—
0
0
2671
26267
1.10
1.21
41.4
25.7
4.04
4.02
mmol/l
5.28
2641
25693
8
37
2.16
1.21
1.4
2.4
0.13
0.43
u/field
—
8
37
22
140
1.58
1.20
1.0
1.0
—
—
—
0
0
41
298
1.38
1.18
1.8
2.0
1.67
1.33
u/field
0.24
24
159
2363
24113
0.93
1.17
5.4
5.5
4.24
4.32
mmol/l
3.22
2132
21935
14
234
0.60
1.13
1.1
1.0
797.56
644.01
ng/l
—
9
150
1954
19011
1.07
1.12
4.3
4.1
14.99
15.12
pmol/l
1.36
1793
16947
8
40
2.00
1.12
1.3
1.1
—
991.67
—
0
12
322
2913
1.12
1.10
3.7
2.7
0.53
0.52
e6/l
0.02
311
2822
7
31
2.26
1.10
1.6
1.7
—
—
—
0
0
7
31
2.26
1.10
2.4
1.3
—
—
—
0
0
5
21
2.38
1.09
1.0
1.0
—
—
—
0
0
339
3084
1.11
1.06
1.3
1.3
—
—
—
0
0
364
3978
0.90
1.05
1.4
1.4
—
—
—
0
0
56
713
0.78
1.05
1.1
1.1
—
—
—
0
0
24
162
1.49
1.04
1.0
1.1
—
—
—
0
0
172
1503
1.15
1.03
2.6
2.2
0.19
0.64
estimate
0.30
52
394
133
1147
1.17
0.96
3.2
3.0
388.98
378.62
mg/l
0.04
66
495
8
144
0.55
0.93
1.3
1.0
204.38
302.81
mg/l
—
8
122
6
29
2.07
0.89
1.0
1.1
—
—
—
0
0
1109
10663
1.06
0.87
2.6
2.4
—
—
—
0
0
155
1757
0.88
0.87
5.1
3.8
1.02
1.02
ratio
0.19
147
1602
1042
10005
1.06
0.86
1.9
1.8
18.77
19.72
nmol/l
1.30
926
8383
15
96
1.57
0.84
1.6
2.0
—
—
—
0
0
734
6977
1.07
0.84
1.5
1.3
—
—
—
0
0
43
336
1.28
0.83
1.4
1.2
—
—
—
0
0
6
113
0.53
0.83
1.0
1.1
—
—
—
0
0
15
97
1.55
0.81
1.5
1.9
—
—
—
0
0
150
1327
1.14
0.80
1.2
1.2
—
—
—
0
0
2642
26083
1.07
0.79
23.6
13.2
23.58
25.04
u/l
4.55
2606
25078
2435
24706
0.94
0.77
6.1
6.4
2.40
2.46
mmol/l
2.85
2199
22375
31
405
0.76
0.76
1.5
1.7
—
—
—
0
0
36
460
0.78
0.75
1.8
1.7
—
—
—
0
0
9
54
1.67
0.74
1.2
1.0
—
—
—
0
0
12
183
0.65
0.72
1.5
1.6
100.00
92.08
umol/l
0.32
12
183
9
57
1.58
0.71
2.7
1.0
16.76
16.59
umol/l
—
9
45
18
126
1.43
0.70
1.2
1.4
6.07
16.00
umol/l
1.04
13
79
14
93
1.51
0.69
1.8
1.2
48.73
66.16
%
1.10
14
80
14
204
0.68
0.68
1.6
4.6
32.94
66.45
u/ml
1.00
14
199
59
704
0.84
0.68
5.2
3.8
26.86
31.43
mg/l
0.59
49
507
25
187
1.34
0.68
1.0
1.1
—
—
—
0
0
7
121
0.58
0.67
1.1
1.4
89.07
153.30
pmol/l
—
7
121
24
179
1.34
0.66
1.4
1.5
60.53
68.62
%
0.49
19
147
2415
24471
0.95
0.66
5.7
5.9
6.10
6.14
mmol/l
0.72
2176
21847
2267
22997
0.95
0.63
4.7
4.6
1.31
1.26
mmol/l
3.21
2008
20460
34
270
1.26
0.62
1.8
2.2
492.64
637.78
ml
1.85
22
162
50
415
1.21
0.62
1.4
1.3
9.51
9.35
u/l
0.04
45
330
11
164
0.67
0.61
1.8
1.8
—
—
—
0
0
1338
13721
0.96
0.59
5.0
6.3
3.36
4.04
ug/l
0.29
1155
12255
143
1581
0.90
0.59
2.2
2.5
29.12
20.59
au/ml
0.35
11
103
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
97
857
1.14
0.58
1.4
1.5
0.21
0.33
mg/l
2.53
39
357
23
175
1.32
0.58
1.2
1.5
14.53
15.64
umol/l
0.28
23
159
37
302
1.23
0.55
2.9
2.0
—
—
—
0
0
129
1426
0.90
0.55
1.2
1.3
78.24
57.69
au/ml
—
5
110
63
542
1.17
0.55
1.6
1.3
1.05
0.82
nmol/l
1.49
50
444
14
100
1.40
0.51
1.1
1.1
—
—
—
0
0
2678
26540
1.05
0.51
44.6
27.8
89.12
87.39
umol/l
1.35
2649
26143
64
556
1.15
0.50
1.9
1.8
20.09
15.78
iu/l
0.08
24
192
16
213
0.75
0.50
1.2
1.9
120.06
127.85
ng/l
0.11
16
213
14
102
1.37
0.47
3.1
2.1
0.61
0.62
mmol/l
0.17
14
102
10
68
1.47
0.47
1.3
1.3
28.70
12.00
mm/h
—
10
68
93
835
1.12
0.46
13.7
12.9
—
—
—
0
0
23
182
1.27
0.46
1.5
1.6
—
—
—
0
0
134
1461
0.91
0.46
2.3
2.1
—
—
—
0
0
7
50
1.40
0.45
1.3
1.3
—
—
—
0
0
21
165
1.27
0.45
1.2
1.4
1.02
1.09
nmol/l
0.20
15
110
10
141
0.71
0.44
2.1
1.7
16.82
15.51
nmol/l
—
10
128
386
3682
1.05
0.44
3.3
4.1
17.26
21.45
ug/l
0.27
326
3081
16
208
0.77
0.43
2.8
2.7
—
—
—
0
0
28
339
0.82
0.43
2.4
1.5
152.75
311.81
pmol/l
1.90
28
332
15
195
0.77
0.41
1.6
1.7
—
—
—
0
0
20
250
0.80
0.41
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
8
59
1.36
0.41
1.4
1.1
—
—
—
0
0
83
918
0.90
0.39
5.9
4.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
19
237
0.80
0.39
1.2
1.4
—
—
—
0
0
105
964
1.09
0.37
5.7
3.5
1.66
1.67
mmol/l
0.06
105
940
45
514
0.87
0.37
1.0
1.1
—
—
—
0
0
48
544
0.88
0.35
1.2
1.3
8.13
38.51
e6/l
1.16
32
407
5
79
0.63
0.35
1.2
1.5
7.34
7.13
mmol/l
—
5
79
994
9727
1.03
0.35
3.0
2.7
—
—
—
0
0
6
44
1.36
0.34
7.0
13.5
5.65
5.39
mmol/l
—
6
44
94
864
1.09
0.33
1.7
1.6
29.37
25.80
u/ml
0.15
17
152
309
3224
0.95
0.33
5.2
4.7
7.36
7.36
ph
0.25
257
2291
1453
14317
1.03
0.31
2.3
2.3
89.48
92.87
pmol/l
1.91
822
7748
49
549
0.89
0.31
1.2
1.4
29.82
652.64
e6/l
2.13
39
438
89
819
1.09
0.31
6.3
3.6
7.50
7.72
mmol/l
0.37
89
799
123
1317
0.93
0.31
2.4
3.1
295.55
2194.37
u/ml
1.33
100
1134
157
1666
0.94
0.31
1.2
1.3
—
—
—
0
0
2682
26661
1.03
0.30
50.1
31.0
242.19
236.09
e9/l
4.56
2643
25988
2682
26662
1.03
0.30
49.9
30.9
92.93
91.94
fl
19.35
2656
26245
2682
26663
1.03
0.30
50.0
31.0
4.34
4.37
e12/l
1.65
2641
25885
2682
26663
1.03
0.30
52.1
31.6
39.77
39.43
%
2.66
2656
26235
2682
26663
1.03
0.30
49.8
30.9
30.61
30.50
pg
2.13
2657
26245
12
152
0.79
0.29
1.1
1.1
143.08
138.50
nmol/l
0.07
12
152
2682
26665
1.03
0.29
50.4
31.2
131.52
132.14
g/l
1.26
2659
26266
2682
26666
1.03
0.29
50.1
31.0
8.04
7.01
e9/l
72.35
2642
25883
17
206
0.82
0.29
1.5
1.7
—
—
—
0
0
8
110
0.73
0.28
1.3
1.2
6.35
6.27
mmol/l
—
8
104
11
140
0.78
0.28
2.4
2.5
—
—
—
0
0
17
205
0.83
0.28
1.5
1.7
—
—
—
0
0
17
204
0.83
0.27
1.5
1.5
—
—
—
0
0
31
272
1.14
0.26
1.1
1.2
278.54
331.06
nmol/l
0.73
24
211
286
2965
0.96
0.25
2.7
2.2
0.00
0.01
estimate
0.78
65
529
17
202
0.84
0.24
1.5
1.7
—
—
—
0
0
2335
23195
1.02
0.24
5.5
5.2
2.08
2.06
mu/l
0.45
2151
20877
14
115
1.22
0.23
1.6
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
225.55
—
0
11
0
11
0.00
0.21
0.0
1.7
—
0.17
—
0
11
0
10
0.00
0.21
0.0
1.1
—
0.20
—
0
10
5
43
1.16
0.21
1.0
1.3
—
—
—
0
0
8
105
0.76
0.21
2.1
2.1
—
—
—
0
0
160
1670
0.96
0.20
2.8
2.9
—
—
—
0
0
121
1155
1.05
0.18
1.1
1.2
148.81
121.92
u/ml
0.31
35
394
1962
19494
1.02
0.17
44.6
27.3
329.14
331.27
g/l
20.92
1950
19341
5
66
0.76
0.17
1.0
1.2
—
—
—
0
0
42
389
1.08
0.16
2.7
2.6
—
—
—
0
0
24
216
1.11
0.15
2.7
3.1
—
—
—
0
0
20
178
1.12
0.15
1.4
1.3
—
—
—
0
0
13
112
1.16
0.14
1.1
1.5
—
2.00
—
0
5
10
84
1.19
0.14
1.6
1.9
—
—
—
0
0
28
304
0.92
0.13
1.4
1.3
—
—
nmol/l
—
0
0
16
143
1.12
0.11
5.9
4.1
—
—
—
0
0
2395
24023
0.99
0.10
7.6
7.6
41.35
40.69
mmol/mol
2.39
2215
21991
10
114
0.88
0.09
1.0
1.1
—
—
—
0
0
33
311
1.06
0.09
1.3
1.2
0.21
0.20
nmol/l
0.12
24
256
6
54
1.11
0.09
6.5
5.7
8.43
8.52
mmol/l
—
6
54
13
117
1.11
0.08
1.5
2.1
564.29
780.21
e6/l
—
7
84
14
154
0.91
0.08
1.3
1.8
37.24
39.39
g/l
0.76
14
154
6
71
0.84
0.07
1.7
1.4
—
—
—
0
0
6
71
0.84
0.07
1.5
1.5
—
—
—
0
0
6
70
0.86
0.07
1.3
1.7
59.33
663.44
nmol/24h
—
6
70
7
82
0.85
0.07
2.7
1.8
0.00
0.07
estimate
—
7
82
17
157
1.08
0.07
5.7
3.9
—
—
—
0
0
239
2360
1.01
0.06
4.2
3.1
6.19
6.04
ph
2.36
191
1708
47
483
0.97
0.04
2.2
1.8
216.60
203.61
pmol/l
0.39
42
451
11
119
0.92
0.04
1.2
1.5
65.67
90.19
umol/l
—
6
72
746
7435
1.00
0.03
3.0
2.6
—
—
—
0
0
38
370
1.03
0.03
1.0
1.1
1.46
50.26
iu/ml
—
9
57
18
172
1.05
0.02
2.7
5.4
114.17
21.74
u/ml
—
6
54
245
2437
1.01
0.02
3.1
2.2
12.75
12.25
nmol/l
0.47
213
2100
83
822
1.01
0.01
2.1
2.3
117.84
95.53
ug/min
0.23
46
485
27
271
1.00
0.00
1.1
1.3
—
—
—
0
0
94
936
1.00
0.00
1.3
1.3
—
—
—
0
0
35
347
1.01
0.00
1.2
1.3
284.59
285.58
pmol/l
0.01
29
288
6
65
0.92
0.00
1.8
1.8
1.87
1.25
ug/l
—
6
59
6
69
0.87
0.00
3.8
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
342.67
—
0
6
9
97
0.93
-0.00
1.2
1.3
111.89
169.15
mmol/24h
—
9
97
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1978.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
-0.00
1.9
2.5
2.63
424.02
ug/l
—
8
82
0
5
0.00
-0.00
0.0
1.0
—
0.05
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
39.33
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
32
320
1.00
-0.00
1.4
1.5
30.05
32.44
ng/l
0.10
32
320
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
386.50
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1481.75
—
0
8

Mortality – FinRegistry

Association

Association between endpoint IPF and mortality.

Females

Parameter HR [95% CI] p-value
IPF 3.691 [3.29, 4.14] < 0.001
Birth year 0.992 [0.98, 1.0] 0.045

During the follow-up period (1.1.1998 — 31.12.2019), 3391 out of 5474 females with IPF died.

Males

Parameter HR [95% CI] p-value
IPF 3.607 [3.15, 4.13] < 0.001
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 5042 out of 7688 males with IPF died.

Mortality risk

Mortality risk for people of age

years, who have IPF.

N-year risk Females Males
1 0.269% 0.673%
5 1.736% 3.833%
10 4.577% 9.627%
15 8.667% 17.651%
20 15.51% 28.109%

Relationships between endpoints

Index endpoint: IPF – Idiopathic pulmonary fibrosis

GWS hits: 13

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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