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Benign neoplasm: Short bones of upper limb

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_BONE_SHORT_UPPER

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D16.1&
  • Hospital discharge: ICD-9 — 2135
  • Hospital discharge: ICD-8 — 21304
  • Cause of death: ICD-10 — D16.1&
  • Cause of death: ICD-9 — 2135
  • Cause of death: ICD-8 — 21304

2 out of 7 registries used, show all original rules.

642

4. Check minimum number of events

None

642

5. Include endpoints

None

642

6. Filter based on genotype QC (FinnGen only)

588

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum ossium brevium membri superioris

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4153 2166 1973
Only index persons 3902 2072 1830
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.06
Only index persons 0.07 0.08 0.07
Median age at first event (years)
Whole population 38.27 40.19 36.12
Only index persons 38.06 40.09 35.77

-FinnGen-

Key figures

All Female Male
Number of individuals 588 381 207
Unadjusted period prevalence (%) 0.12 0.14 0.09
Median age at first event (years) 43.46 43.45 43.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
604
Matched controls
6040
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
+∞
307.7
462
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
113.6
307.7
204
27
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
27.6
102.0
71
29
2135A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of upper limb
+∞
94.3
88
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
6.1
78.0
167
358
21304
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis superioris
+∞
63.7
60
*
9102
FHL
Trepanation or removal of the local bone process
94.1
61.3
67
8
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
16.8
44.7
38
24
WX204
NOMESCO Finland
Axillary plexus blockaced
7.3
43.8
68
103
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
10.3
40.9
47
49
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
8.4
31.5
42
53
NDK10
NOMESCO Finland
Incision or excision of a bone of hand
59.9
29.4
34
6
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
135.6
24.8
26
*
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
62.3
21.0
24
*
S62.6
ICD-10 Finland
Fracture of other finger
4.4
20.8
55
135
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
59.6
20.0
23
*
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
13.4
15.8
27
21
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
14.6
14.6
24
17
WX203
NOMESCO Finland
Infraclavicular plexus blockade
5.2
14.5
30
60
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
6.6
14.2
23
36
ND2CG
NOMESCO Finland
Extensive MRI of hand
43.6
14.2
17
*
ND1AA
NOMESCO Finland
Wrist X-ray examination
3.0
13.6
63
225
NDK00
NOMESCO Finland
Excision or incsion of a bone of wrist
143.1
13.5
14
*
9104
FHL
Autogenous bone graft
132.7
12.5
13
*
ND3CG
NOMESCO Finland
Extensive MRI of fingers
66.3
11.6
13
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
4.8
11.5
26
56
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
35.8
11.3
14
*
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
44.2
11.0
13
*
ND2AA, ,
SPAT
2.8
10.8
57
218
M67.4
ICD-10 Finland
Ganglion
2.6
10.1
61
250
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
4.5
9.9
24
55
UJF32
NOMESCO Finland
Coloscopy
1.9
9.7
161
986
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
+∞
9.4
9
*
L12
ICPC
Hand/finger symptom/complaint
2.0
9.3
124
706
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
9.2
131
760
SPAT1153
SPAT
Removal of sutures
1.8
9.2
187
1213
M01AH05
ATC
etoricoxib; oral
1.7
9.2
409
3295
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.5
9.1
22
50
ND2BG
NOMESCO Finland
MRI of hand
14.3
8.7
14
10
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
4.1
8.7
24
61
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
8.5
281
2075
D16
ICD-10 Finland
Benign neoplasm of bone and articular cartilage
+∞
8.3
8
*
ZZH20
NOMESCO Finland
Graft of patients own bone
14.7
8.2
13
9
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
8.1
277
2056
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.9
8.1
38
137
M54.5
ICD-10 Finland
Low back pain
1.6
7.6
239
1729
A02BC02
ATC
pantoprazole; systemic
1.6
7.4
408
3372
N02AX02
ATC
tramadol; systemic, rectal
1.6
7.4
255
1882
Q78.48
ICD-10 Finland
Enchondromatosis
+∞
7.3
7
*
ZXA05
NOMESCO Finland
Left side
1.7
7.0
136
865
X58
ICD-10 Finland
Exposure to other specified factors
1.8
6.8
105
622
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
6.2
6.8
17
28
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.7
6.6
34
129
N02BF02
ATC
pregabalin; oral
2.3
6.4
47
212
NC2AA
NOMESCO Finland
Forearm X-ray examination
5.3
6.4
18
35
M25.5
ICD-10 Finland
Pain in joint
1.6
6.3
221
1622
ND2BG, ,
SPAT
18.2
6.3
9
5
M85.4
ICD-10 Finland
Solitary bone cyst
27.0
6.2
8
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.0
6.1
70
375
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
3.0
6.1
27
94
ND1BG, ,
SPAT
4.2
6.1
16
39
N02BE01
ATC
paracetamol; systemic, rectal
1.9
6.0
537
4872
M79.6
ICD-10 Finland
Pain in limb
1.5
6.0
273
2117
ZZH40
NOMESCO Finland
Substitute of bone
6.1
6.0
15
25
WX202
NOMESCO Finland
Supraclavicular plexus blockade
5.6
6.0
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
170
1056
1.85
9.77
1.3
1.3
9.88
10.67
u/ml
0.06
65
437
302
2228
1.71
9.48
2.1
2.1
—
—
—
0
0
173
1156
1.70
7.45
1.4
1.3
20.36
28.11
iu/ml
0.73
46
366
196
1380
1.62
6.79
2.4
2.6
322.45
334.48
umol/l
0.95
165
1251
118
792
1.61
4.80
2.7
2.6
141.70
107.43
ug/g
0.71
84
633
120
814
1.59
4.66
2.2
2.4
2.38
2.36
g/l
0.15
110
756
124
859
1.56
4.39
1.4
1.4
640.00
517.39
titre
0.22
29
184
125
873
1.54
4.26
2.2
2.4
14.55
13.70
umol/l
0.66
111
817
471
4233
1.51
4.24
4.6
4.4
14.77
14.60
pmol/l
0.80
443
3942
229
1809
1.43
4.20
6.6
6.2
—
—
—
0
0
73
448
1.72
4.18
1.2
1.2
—
—
—
0
0
110
774
1.51
3.60
1.2
1.2
—
—
—
0
0
180
1394
1.41
3.59
1.5
1.3
2.47
1.51
u/ml
0.21
43
417
214
1717
1.38
3.44
2.8
2.5
56.60
64.02
u/l
0.97
187
1605
584
5603
2.28
3.41
19.2
18.2
74.47
74.24
umol/l
0.06
578
5553
531
4959
1.59
3.39
5.8
5.4
1.78
1.86
mu/l
1.05
499
4658
564
5352
1.81
3.35
16.5
16.2
3.96
3.96
mmol/l
0.25
551
5246
452
4098
1.41
3.30
8.2
8.3
73.38
78.60
u/l
3.46
429
3898
563
5345
1.79
3.26
16.2
16.1
139.73
139.72
mmol/l
0.02
551
5251
168
1305
1.40
3.25
2.5
2.1
2.69
2.82
mg/l
0.28
143
1141
69
448
1.61
3.21
4.2
4.2
7.35
7.36
ph
0.05
50
324
102
724
1.49
3.20
2.9
3.4
3.89
5.71
e9/l
1.36
85
649
161
1250
1.39
3.11
1.5
1.5
2.16
2.32
g/l
0.77
96
810
558
5294
1.71
3.11
15.2
14.4
23.00
22.26
mg/l
0.19
481
4283
221
1810
1.35
3.05
2.9
3.3
2.35
2.35
mmol/l
0.29
195
1667
269
2269
1.33
3.04
4.8
4.9
36.79
36.34
g/l
0.71
246
2156
293
2503
1.33
3.03
2.7
2.7
—
—
estimate
—
0
0
103
741
1.47
3.02
2.3
2.4
25.44
23.41
%
0.85
94
701
194
1562
1.36
2.98
3.9
3.7
0.00
0.01
estimate
0.88
76
583
103
743
1.47
2.98
1.8
1.7
1052.49
1205.49
nmol/l
1.21
82
562
39
223
1.80
2.89
1.6
1.3
—
—
—
0
0
310
2692
1.31
2.77
3.4
3.1
101.08
112.62
ug/l
0.64
282
2548
18
78
2.35
2.77
1.4
1.2
—
—
—
0
0
6
10
6.05
2.70
1.2
2.0
—
—
—
0
0
557
5309
1.63
2.69
5.2
5.0
4.71
4.74
mmol/l
0.29
522
5027
342
3042
1.29
2.42
4.1
4.8
6.40
6.60
mmol/l
1.12
322
2884
24
125
1.96
2.39
3.0
2.9
3.42
2.20
index
0.52
12
70
333
2955
1.28
2.38
6.9
6.7
0.21
0.19
e9/l
1.16
298
2606
327
2896
1.28
2.37
3.8
3.7
0.05
0.53
estimate
0.45
75
580
327
2897
1.28
2.36
7.0
6.4
2.07
1.93
e9/l
0.46
290
2583
560
5369
1.59
2.32
5.8
5.6
2.75
2.80
mmol/l
0.61
520
5075
321
2844
1.27
2.29
3.7
3.7
0.00
0.00
estimate
0.50
82
610
63
435
1.50
2.28
3.6
3.6
—
—
—
0
0
283
2470
1.27
2.28
2.5
2.5
78.06
76.25
nmol/l
0.47
251
2270
553
5291
1.53
2.27
5.1
4.9
1.49
1.48
mmol/l
0.27
516
4988
229
1951
1.28
2.23
3.1
3.4
20.09
64.01
ng/l
0.76
143
1263
5
9
5.59
2.21
1.0
1.2
—
—
—
0
0
291
2558
1.27
2.18
6.2
7.1
1.22
1.21
mmol/l
1.47
244
2236
131
1038
1.33
2.18
1.5
1.7
504.29
26936463.30
pmol/l
0.99
94
891
322
2866
1.26
2.17
3.9
3.7
0.04
2.64
estimate
0.49
82
616
167
1372
1.30
2.15
3.1
2.9
—
0.00
estimate
—
0
7
319
2848
1.25
2.05
6.9
6.4
0.04
0.04
e9/l
0.57
280
2470
318
2843
1.25
2.00
7.0
6.4
0.56
0.56
e9/l
0.00
280
2467
88
665
1.38
1.99
1.6
1.4
—
—
—
0
0
348
3148
1.25
1.95
8.4
9.8
3.83
4.02
e9/l
1.15
304
2766
63
451
1.44
1.93
1.3
1.2
195.77
147.81
u/ml
0.32
32
189
262
2299
1.25
1.92
9.9
10.8
1.17
1.17
inr
0.02
212
1909
56
392
1.47
1.92
2.4
2.5
7.39
16.29
au/ml
—
7
41
94
722
1.36
1.92
1.3
1.3
—
—
—
0
0
27
158
1.74
1.92
3.6
2.6
—
—
—
0
0
25
144
1.77
1.88
1.6
1.5
16893.90
11525.53
e6/l
0.30
20
108
591
5778
2.06
1.86
24.0
22.1
259.33
254.20
e9/l
1.16
583
5690
36
230
1.60
1.86
1.6
1.5
246.90
281.76
mu/l
0.57
31
207
591
5780
2.04
1.83
23.9
22.0
4.53
4.53
e12/l
0.01
582
5680
170
1428
1.27
1.81
3.2
3.0
0.49
0.40
e6/l
0.20
131
1027
591
5781
2.04
1.81
24.0
22.1
6.70
6.62
e9/l
0.37
581
5678
529
5058
1.37
1.79
4.4
4.1
1.27
1.29
mmol/l
0.27
487
4741
140
1150
1.28
1.78
2.6
2.5
6.88
6.21
e6/l
0.18
122
1045
39
257
1.55
1.78
1.1
1.1
—
—
—
0
0
258
2279
1.23
1.74
5.4
6.3
1.22
1.21
mmol/l
1.45
240
2115
66
487
1.40
1.73
2.1
2.0
0.00
0.03
estimate
—
10
113
575
5588
1.60
1.72
13.1
11.8
25.97
26.84
u/l
0.83
559
5465
14
68
2.08
1.71
3.3
2.5
—
—
—
0
0
159
1334
1.26
1.70
3.2
3.9
92.62
93.09
%
0.09
154
1306
7
25
2.82
1.65
1.3
1.6
65.57
109.21
ng/l
—
7
25
91
713
1.33
1.64
1.6
1.6
—
—
—
0
0
154
1293
1.26
1.63
2.3
2.2
—
—
—
0
0
80
616
1.34
1.62
1.5
1.6
—
—
—
0
0
23
371
0.60
1.58
1.7
1.7
—
—
—
0
0
200
1735
1.23
1.57
2.3
2.2
—
—
—
0
0
293
2641
1.21
1.57
7.1
6.3
56.00
57.00
%
0.87
274
2535
34
225
1.54
1.55
2.4
2.3
820.81
5258.26
u/l
—
8
93
173
1481
1.24
1.54
2.8
2.8
—
—
—
0
0
21
124
1.72
1.49
1.4
1.2
—
—
—
0
0
247
2199
1.21
1.49
3.7
3.5
0.03
0.01
estimate
0.19
75
514
521
4999
1.31
1.48
6.2
5.9
38.37
38.82
mmol/mol
0.64
485
4755
7
28
2.52
1.45
1.9
2.8
0.86
0.71
index
—
7
28
527
5067
1.31
1.45
5.3
4.8
5.80
5.87
mmol/l
0.77
485
4731
187
1624
1.22
1.44
3.7
3.6
21.83
49.07
mg/l
3.27
116
1060
17
95
1.81
1.44
1.4
1.5
—
—
—
0
0
184
1596
1.22
1.44
2.0
2.1
127.05
180.05
u/l
1.78
179
1517
6
22
2.74
1.43
1.7
1.7
85.00
60.89
ug/l
—
6
22
38
263
1.47
1.43
1.6
2.1
4.28
6.97
iu/ml
—
8
67
288
2610
1.20
1.41
7.3
6.4
0.67
0.70
%
0.31
267
2458
289
2624
1.19
1.38
7.3
6.4
8.65
8.70
%
0.12
269
2483
35
240
1.49
1.38
2.3
2.3
—
—
—
0
0
191
1672
1.21
1.35
3.3
3.1
90.60
91.35
e6/l
0.00
148
1266
10
47
2.15
1.34
1.4
1.1
—
—
—
0
0
25
160
1.59
1.33
1.2
1.1
—
—
—
0
0
115
956
1.25
1.33
3.3
3.7
139.30
451.93
ng/l
2.02
72
674
51
379
1.38
1.32
1.2
1.4
34.40
27.01
iu/l
0.62
42
322
50
662
0.73
1.30
1.3
1.4
—
—
—
0
0
14
242
0.57
1.29
1.1
1.1
1.59
1.56
g/l
0.18
14
242
293
2677
1.18
1.27
7.3
6.4
29.35
28.23
%
1.05
276
2559
287
2618
1.18
1.27
7.2
6.4
3.00
2.82
%
0.61
266
2467
48
356
1.38
1.26
1.1
1.1
—
—
—
0
0
9
45
2.01
1.23
2.4
1.4
1.00
1.33
promille
—
9
34
60
464
1.33
1.22
1.3
1.5
—
—
—
0
0
246
2221
1.18
1.22
2.2
2.0
102.84
96.62
pmol/l
1.06
131
1181
200
1783
1.18
1.14
3.5
3.4
7.39
7.86
mmol/l
0.69
161
1521
184
1630
1.19
1.13
3.0
3.1
0.04
0.06
estimate
0.09
69
501
7
136
0.51
1.11
1.4
1.5
—
—
—
0
0
7
140
0.49
1.10
1.6
1.6
—
—
—
0
0
69
553
1.28
1.10
3.0
2.1
364.24
372.87
nmol/l
0.15
59
526
20
128
1.58
1.09
1.1
1.1
—
—
—
0
0
20
128
1.58
1.09
1.1
1.1
—
—
—
0
0
27
186
1.47
1.08
1.4
1.2
17.54
10.11
u/ml
—
5
35
26
178
1.48
1.07
3.7
3.9
162.50
269.65
mg/l
—
10
75
7
33
2.13
1.06
3.1
4.3
22.29
30.97
mu/l
—
7
33
47
360
1.33
1.04
2.7
3.8
4.59
4.62
pmol/l
0.08
42
323
81
668
1.25
1.03
6.0
5.9
1.04
1.04
mmol/l
0.02
76
630
16
250
0.63
1.02
1.1
1.1
0.98
0.91
g/l
0.45
16
250
15
91
1.66
1.01
1.3
3.3
2.26
2.60
mmol/l
—
5
63
162
1433
1.18
1.00
1.7
1.6
20.81
20.27
nmol/l
0.16
134
1226
17
108
1.59
0.97
1.6
3.3
—
—
—
0
0
36
268
1.37
0.97
2.5
2.1
0.00
0.01
estimate
—
8
93
153
1352
1.18
0.96
5.0
5.0
1.93
2.18
ug/l
0.34
141
1225
186
1670
1.16
0.96
4.3
4.2
2.70
8.64
mg/mmol
4.32
110
1042
145
1281
1.17
0.91
1.6
1.7
0.84
1.15
mg/l
0.85
110
1005
85
718
1.21
0.88
1.6
1.5
—
—
—
0
0
18
120
1.52
0.86
1.3
1.3
—
—
—
0
0
75
629
1.22
0.84
1.9
2.8
7.12
6.90
umol/l
0.04
60
560
6
32
1.88
0.82
1.2
1.4
149.50
153.98
nmol/l
—
6
32
8
48
1.68
0.79
1.4
1.2
—
—
—
0
0
8
48
1.68
0.79
2.6
2.2
—
—
—
0
0
248
2300
1.13
0.79
3.5
3.3
6.35
6.16
ph
1.89
135
1355
32
415
0.76
0.78
2.7
2.6
4.03
4.74
kpa
1.52
32
406
17
115
1.49
0.77
1.6
2.3
129.91
131.29
g/l
0.08
11
93
10
59
1.71
0.76
1.6
1.2
—
—
—
0
0
41
326
1.28
0.74
3.1
2.7
—
—
—
0
0
9
55
1.65
0.73
4.3
1.4
—
—
—
0
0
6
109
0.55
0.73
5.8
4.3
—
—
—
0
0
211
1946
1.13
0.72
3.8
3.7
61.29
77.61
e6/l
0.29
154
1351
9
56
1.62
0.72
1.2
1.8
90.02
90.64
%
—
9
56
5
26
1.93
0.70
1.2
1.2
97.00
137.45
iu/ml
—
5
26
7
41
1.72
0.70
2.4
1.7
1.96
3.82
mg/l
—
7
41
83
718
1.18
0.69
1.3
1.4
—
—
—
0
0
302
2852
1.12
0.68
5.7
6.6
11.18
10.86
umol/l
0.11
283
2723
5
27
1.86
0.68
35.4
29.3
6.52
6.66
ug/l
—
5
22
111
984
1.16
0.68
2.8
2.7
523.05
530.43
mosm/kgh2o
0.12
91
863
39
312
1.27
0.68
1.2
1.2
—
—
—
0
0
57
477
1.22
0.67
3.1
2.8
9.89
10.36
g/l
0.45
49
443
17
119
1.44
0.67
2.0
2.2
34.45
126.00
ug/min
—
8
67
40
489
0.81
0.64
2.9
3.3
7.39
7.39
ph
0.30
29
286
72
622
1.18
0.62
1.5
1.7
—
—
—
0
0
5
30
1.67
0.61
3.2
3.8
578.80
658.77
u/ml
—
5
30
54
455
1.21
0.61
1.4
1.4
—
—
—
0
0
23
174
1.33
0.61
1.1
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
58.33
—
0
21
30
238
1.27
0.58
3.9
3.1
—
—
—
0
0
26
330
0.78
0.57
2.3
2.4
29.40
81.67
u/ml
0.79
26
316
14
98
1.44
0.57
1.5
1.4
—
—
—
0
0
41
492
0.82
0.56
2.7
3.3
6.06
5.73
kpa
1.45
41
482
20
262
0.76
0.56
1.7
2.4
0.67
0.62
%
0.34
20
262
10
65
1.55
0.55
2.0
1.6
44.20
27.00
ng/l
—
10
65
6
37
1.63
0.55
12.0
2.9
295.67
827.70
mg
—
6
37
62
535
1.18
0.55
4.9
8.6
0.86
0.99
mmol/l
0.12
51
452
27
214
1.27
0.53
1.4
1.8
20.14
20.98
s
0.45
21
192
9
62
1.46
0.53
1.1
1.1
—
—
—
0
0
9
62
1.46
0.53
1.7
1.3
—
—
—
0
0
61
528
1.17
0.53
2.7
3.0
1.76
1.81
%
0.13
52
482
135
1237
1.12
0.52
4.0
3.7
1.02
1.02
kg/l
0.43
92
832
6
40
1.50
0.51
1.0
1.1
155.17
218.50
mg/l
—
6
34
9
64
1.41
0.51
1.0
1.3
—
—
nmol/l
—
0
0
152
1406
1.11
0.49
4.8
4.9
—
—
—
0
0
62
542
1.16
0.48
4.9
8.6
7.43
7.42
ph
1.31
31
304
108
983
1.12
0.47
2.7
2.7
2.42
2.44
mmol/l
1.23
97
894
262
2493
1.09
0.47
10.4
10.6
0.00
0.00
e9/l
0.76
215
2039
209
1970
1.09
0.46
3.0
3.4
28.48
32.53
u/l
1.59
193
1877
17
129
1.33
0.46
1.4
1.2
3.73
12.81
e6/l
0.92
11
97
17
129
1.33
0.46
1.4
1.2
—
—
—
0
0
12
86
1.40
0.44
1.3
1.2
21.12
15.73
u/l
0.20
12
71
47
405
1.17
0.44
2.7
3.9
1.24
1.23
mmol/l
1.35
41
350
49
426
1.16
0.42
2.3
2.3
5.94
6.11
ph
0.40
26
265
245
2338
1.08
0.40
1.8
1.9
1.43
1.39
mmol/l
0.24
205
2007
12
88
1.37
0.40
1.1
1.2
—
—
—
0
0
43
372
1.17
0.40
1.8
2.3
3.46
7.86
ug/l
3.26
35
339
149
1394
1.09
0.39
2.2
3.1
767.56
862.62
ng/l
0.16
120
1175
5
35
1.43
0.39
1.0
1.1
919.40
1750.11
miu/ml
—
5
35
167
1573
1.09
0.38
3.9
4.1
7.39
7.40
ph
1.25
123
1104
12
158
0.75
0.37
10.8
7.4
—
—
—
0
0
43
379
1.14
0.33
1.2
1.2
—
—
—
0
0
6
46
1.31
0.33
1.3
1.4
7.82
6.06
ug/l
—
6
40
6
47
1.28
0.32
1.2
1.0
—
—
—
0
0
6
47
1.28
0.32
1.0
1.8
7.63
11.13
%
—
6
47
398
3887
1.07
0.32
3.7
3.3
41.56
46.36
u/l
0.80
366
3705
7
52
1.35
0.31
2.7
2.3
—
—
—
0
0
88
814
1.09
0.31
3.1
2.8
3.01
2.73
e6/l
0.10
48
385
7
54
1.30
0.30
9.6
2.4
—
—
—
0
0
12
94
1.28
0.28
1.3
1.2
—
—
—
0
0
20
169
1.19
0.26
1.8
2.2
10.61
10.31
g/l
0.11
15
157
12
149
0.80
0.26
1.3
1.3
73.92
138.51
pmol/l
0.69
12
144
154
1611
0.94
0.25
1.5
1.5
—
—
—
0
0
9
75
1.20
0.25
1.0
1.3
0.53
0.58
nmol/l
—
9
70
13
105
1.24
0.25
1.6
2.2
5.19
5.13
mmol/24h
0.03
13
91
9
76
1.19
0.24
1.4
1.3
—
52.11
—
0
7
19
161
1.19
0.24
2.4
1.7
—
—
—
0
0
38
341
1.12
0.24
3.8
3.1
7.43
7.42
ph
0.71
29
280
55
507
1.09
0.22
2.2
2.4
43.96
35.44
u/l
0.25
50
431
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
1.81
—
0
10
0
10
0.00
0.21
0.0
3.5
—
—
—
0
0
0
10
0.00
0.21
0.0
3.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.44
—
0
10
139
1331
1.06
0.21
3.4
4.3
—
—
—
0
0
66
616
1.08
0.21
1.6
1.4
—
—
—
0
0
121
1155
1.06
0.20
2.0
1.9
—
—
—
0
0
9
114
0.79
0.20
1.0
1.1
—
—
—
0
0
6
50
1.20
0.19
2.8
2.1
47.67
38.87
%
—
6
50
51
472
1.09
0.19
5.4
9.0
121.65
121.37
g/l
0.04
51
464
53
492
1.08
0.19
4.4
4.5
17.99
17.53
ug/l
0.01
44
400
16
137
1.17
0.19
1.1
1.2
3.41
3.74
mmol/l
1.13
16
130
18
206
0.87
0.18
1.3
1.2
—
—
—
0
0
7
58
1.21
0.18
1.0
1.3
—
—
—
0
0
102
973
1.06
0.18
1.7
1.7
—
—
—
0
0
23
257
0.89
0.17
1.1
1.5
—
—
—
0
0
59
628
0.93
0.17
2.1
1.7
—
—
—
0
0
7
63
1.11
0.17
1.0
1.3
—
—
—
0
0
43
398
1.09
0.17
3.1
3.1
73.11
72.67
e9/l
0.03
31
278
5
69
0.72
0.17
1.8
3.0
—
—
—
0
0
5
70
0.71
0.16
1.4
1.1
—
—
—
0
0
8
68
1.18
0.16
2.3
2.3
—
—
—
0
0
45
418
1.08
0.16
6.3
8.8
—
—
—
0
0
23
256
0.89
0.16
1.1
1.5
—
—
—
0
0
11
130
0.84
0.16
1.3
1.4
—
—
—
0
0
29
264
1.10
0.16
2.3
5.1
—
—
—
0
0
6
79
0.76
0.15
1.2
1.1
—
—
—
0
0
23
255
0.90
0.15
1.1
1.5
—
—
—
0
0
14
161
0.87
0.15
1.9
2.1
6.16
5.03
iu/l
—
7
67
18
159
1.14
0.15
1.1
1.2
—
—
—
0
0
9
83
1.09
0.14
3.8
3.8
0.11
1.08
%
—
9
77
23
254
0.90
0.14
1.1
1.5
—
—
—
0
0
53
499
1.07
0.14
4.6
4.6
0.06
0.17
%
0.95
18
130
22
198
1.12
0.14
1.9
2.4
1.55
1.45
g/l
0.17
17
176
12
103
1.17
0.14
1.3
1.8
—
—
—
0
0
16
180
0.89
0.13
1.3
1.8
—
—
—
0
0
48
452
1.07
0.13
2.1
2.4
12.44
13.44
nmol/l
0.42
42
420
24
219
1.10
0.13
1.3
1.3
225.30
224.32
miu/ml
0.00
11
108
10
85
1.18
0.12
1.2
1.1
—
—
—
0
0
41
385
1.07
0.12
2.0
1.9
1.77
1.28
g/l
0.52
36
361
15
133
1.13
0.12
1.1
1.1
1.52
1.75
u/ml
—
7
63
20
220
0.91
0.12
2.3
4.0
36.82
36.94
°c
0.63
20
220
10
116
0.86
0.12
2.8
3.0
27.00
31.28
umol/l
—
10
105
14
157
0.89
0.11
1.6
1.3
—
—
—
0
0
12
105
1.15
0.11
1.0
1.0
—
—
—
0
0
10
86
1.17
0.11
1.2
1.1
1.45
1.47
g/l
—
10
79
12
136
0.88
0.11
4.0
3.4
57.25
57.90
%
0.05
12
136
15
167
0.90
0.11
2.4
2.7
11.43
11.48
mg/l
0.01
15
159
5
44
1.14
0.10
1.2
1.2
—
—
—
0
0
5
45
1.11
0.10
1.0
1.0
—
—
—
0
0
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
5
46
1.09
0.09
2.8
1.5
90.80
71.78
umol/l
—
5
46
5
46
1.09
0.09
1.0
1.1
126.00
112.09
pmol/l
—
5
46
65
675
0.96
0.09
5.2
6.9
104.31
104.24
mmol/l
0.04
65
675
158
1610
0.97
0.08
5.7
6.1
—
—
—
0
0
5
64
0.78
0.08
3.0
2.9
—
—
—
0
0
7
64
1.09
0.08
3.0
1.8
36.57
32.81
pg
—
7
64
21
195
1.08
0.08
3.4
5.6
0.93
0.88
%
0.27
21
185
10
112
0.89
0.07
2.1
1.8
—
—
—
0
0
9
88
1.02
0.07
1.3
1.2
—
—
—
0
0
21
198
1.06
0.05
1.1
1.5
—
—
—
0
0
19
180
1.06
0.04
1.2
1.5
16.16
9.91
u/l
0.49
14
148
10
109
0.92
0.04
1.0
1.0
4.94
5.09
u/ml
—
5
52
21
219
0.96
0.03
2.1
1.9
—
—
—
0
0
54
530
1.02
0.02
4.6
4.5
1.11
1.10
%
0.01
19
161
15
143
1.05
0.01
2.6
2.5
8.61
8.31
kpa
0.30
15
143
52
512
1.02
0.01
5.3
4.9
0.00
0.15
%
1.09
18
118
82
827
0.99
0.01
3.0
3.0
0.62
0.73
ug/l
1.17
53
501
12
114
1.05
0.00
1.1
1.0
0.54
0.71
u/ml
—
6
52
10
105
0.95
0.00
4.6
3.7
4.16
4.24
e9/l
—
10
105
11
105
1.05
0.00
1.0
1.0
0.09
0.92
u/ml
—
6
40
23
235
0.98
0.00
1.1
1.5
—
—
—
0
0
54
545
0.99
0.00
1.7
1.8
3.28
3.53
mmol/l
0.62
36
403
10
98
1.02
0.00
1.6
1.7
—
—
—
0
0
11
108
1.02
0.00
1.1
1.7
—
—
—
0
0
19
192
0.99
0.00
1.2
1.3
—
—
—
0
0
22
222
0.99
0.00
2.9
5.2
1.68
1.58
%
0.27
22
212
28
282
0.99
0.00
1.6
1.6
0.39
0.31
mg/l
0.33
18
128
76
757
1.00
0.00
1.8
2.0
—
—
—
0
0
51
508
1.00
0.00
4.5
4.4
0.26
0.71
%
1.88
19
146
17
169
1.01
0.00
1.2
1.4
258.04
304.77
ug/g
—
5
101
242
2415
1.00
0.00
3.1
3.0
—
—
—
0
0
0
9
0.00
0.00
0.0
4.1
—
6.98
—
0
9
5
58
0.86
0.00
1.2
1.1
1.59
1.41
nmol/l
—
5
52
0
9
0.00
0.00
0.0
7.1
—
12.11
—
0
9
5
55
0.91
-0.00
1.0
1.3
—
—
—
0
0
11
110
1.00
-0.00
2.5
3.0
7.75
7.17
pmol/l
0.14
11
110
5
53
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.1
—
—
—
0
0
7
77
0.91
-0.00
2.1
1.6
—
—
—
0
0
7
77
0.91
-0.00
2.1
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.8
—
0.29
—
0
6
5
50
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
347.33
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
38.57
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
0
6
0.00
-0.00
0.0
3.8
—
0.20
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
15.93
—
0
5
7
77
0.91
-0.00
2.1
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
244.80
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
50.29
—
0
7
5
55
0.91
-0.00
4.6
4.4
—
—
—
0
0
7
77
0.91
-0.00
2.1
1.6
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_BONE_SHORT_UPPER and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SHORT_UPPER 0.944 [0.72, 1.23] 0.672
Birth year 0.997 [0.99, 1.01] 0.516

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 1306 females with CD2_BENIGN_BONE_SHORT_UPPER died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SHORT_UPPER 1.044 [0.83, 1.31] 0.71
Birth year 0.988 [0.98, 1.0] 0.016

During the follow-up period (1.1.1998 — 31.12.2019), 86 out of 1186 males with CD2_BENIGN_BONE_SHORT_UPPER died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BONE_SHORT_UPPER.

N-year risk Females Males
1 0.111% 0.233%
5 0.545% 1.21%
10 1.497% 3.125%
15 2.917% 5.91%
20 5.199% 10.258%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_BONE_SHORT_UPPER – Benign neoplasm: Short bones of upper limb

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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