oropharynx cancer: A primary or metastatic malignant neoplasm that affects the oropharynx.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
528 |
4. Check minimum number of eventsNone |
528 |
5. Include endpointsNone |
528 |
6. Filter based on genotype QC (FinnGen only) |
484 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D14
- Name in latin
- Neoplasma benignum bronchi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Bronchus and lung
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of middle ear and respiratory system
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3012 | 1351 | 1630 |
| Only index persons | 2312 | 1123 | 1189 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.05 |
| Only index persons | 0.04 | 0.04 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 57.62 | 56.60 | 58.38 |
| Only index persons | 56.62 | 55.59 | 57.59 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 484 | 213 | 271 |
| Unadjusted period prevalence (%) | 0.10 | 0.08 | 0.12 |
| Median age at first event (years) | 58.68 | 55.43 | 61.24 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 493
- Matched controls
- 4930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D14.3
ICD-10 Finland
Benign neoplasm: Bronchus and lung
+∞
307.7
387
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
38.4
275.0
185
76
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
20.1
263.9
293
335
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
118.7
83.1
88
9
2123A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Bronchus and lung
+∞
82.7
77
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.7
82.6
140
242
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
265.2
47.9
48
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
12.9
46.1
46
39
GDA20
NOMESCO Finland
Excision of lesion of lung
478.9
45.0
44
*
21230
ICD-8 Finland
Benign neoplasm of respiratory system, Bronchus and lung
+∞
35.9
34
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
33.8
155
572
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
82.6
28.1
31
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
10.3
27.9
32
33
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
5.1
27.2
61
132
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
7.1
26.8
42
64
GD1AD
NOMESCO Finland
Thorax CT examination
4.4
26.4
72
183
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.6
25.4
65
157
5823
FHL
Lung avobiopsy and wedge resection
87.7
22.9
25
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.6
20.5
52
124
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
19.6
296
1899
WX402
NOMESCO Finland
General anaesthesia
2.4
16.3
139
684
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
27.3
15.7
21
8
5822
FHL
Exploratory thoracotomy and small procedure (eg lung suture)
165.0
15.6
16
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
15.0
86
347
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
13.5
85
360
N02AX02
ATC
tramadol; systemic, rectal
2.0
13.0
251
1675
8240/3-C34.9
ICD-O-3
Neuroendocrine tumor, NOS, of lung, NOS
+∞
12.6
12
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
12.4
76
317
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
9.6
12.1
24
26
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
11.5
11
*
GDC00
NOMESCO Finland
Lobectomy of lung
20.6
11.2
16
8
R05
ICD-10 Finland
Cough
2.1
11.2
122
655
1240
FHL
Bronchoscopy
8.9
11.1
23
27
5188X
ICD-9 Finland
Other diseases of lung
61.4
10.7
12
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
8.5
10.4
22
27
2391A
ICD-9 Finland
Neoplasm of unspecified nature, Respiratory system
24.0
10.3
14
6
WX250
NOMESCO Finland
Intercostal blockade
24.0
10.3
14
6
R03BB04
ATC
tiotropium bromide; inhalant
2.4
10.1
75
342
GDA10
NOMESCO Finland
Biopsy of lung
41.0
10.0
12
*
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
20.5
9.8
14
7
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.9
9.8
49
183
R4110
NOMESCO Finland
Physiotherapy
1.9
9.2
154
954
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.8
9.0
45
168
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
8.6
158
1004
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
28.1
8.5
11
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
8.4
138
846
1243
FHL
Bronchoscopy and other therapeutic procedure
+∞
8.4
8
*
23130
ICD-8 Finland
Neoplasm of unspecified nature of respiratory organs, Bronchus and lung
+∞
8.4
8
*
ZXE00
NOMESCO Finland
One hour or less
1.8
8.3
194
1322
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
14.8
8.2
13
9
5826
FHL
Lobectomy or bilobectomy
33.9
8.1
10
*
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
8.0
31
100
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
7.8
36
129
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.9
7.6
37
136
B01AB05
ATC
enoxaparin; parenteral
1.8
7.6
168
1123
D38.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Respiratory organ, unspecified
30.5
7.2
9
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.1
181
1255
B01AB04
ATC
dalteparin; parenteral
2.9
6.8
31
110
R04.2
ICD-10 Finland
Haemoptysis
3.2
6.7
27
89
XG405
NOMESCO Finland
Education on PEF monitoring
6.6
6.7
16
25
N03AX16
ATC
[U] pregabalin
1.8
6.6
122
769
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
70.7
6.4
7
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
6.4
186
1326
D14.4
ICD-10 Finland
Benign neoplasm: Respiratory system, unspecified
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
78
264
3.32
18.72
10.3
8.8
16.93
15.70
%
3.58
78
256
126
564
2.66
18.25
8.1
7.4
1.51
0.91
mmol/l
0.96
110
479
59
176
3.67
17.16
2.3
3.0
—
—
—
0
0
34
68
5.30
16.44
1.3
1.1
—
—
—
0
0
105
482
2.50
14.12
9.3
7.7
125.59
120.51
g/l
1.83
105
474
302
2145
2.05
13.21
14.3
14.3
1.22
1.25
inr
0.43
246
1774
274
1966
1.89
10.69
5.0
5.2
35.64
35.49
g/l
0.17
255
1852
330
2588
1.83
8.93
6.8
5.1
6.76
6.79
mmol/l
0.08
319
2470
37
125
3.12
8.82
2.2
1.4
—
—
—
0
0
314
2440
1.79
8.61
8.4
10.0
4.46
4.15
e9/l
1.51
256
2126
208
1451
1.75
8.21
3.0
3.5
35.95
34.16
u/l
0.10
197
1374
267
2013
1.71
7.84
7.3
6.5
1.20
1.21
mmol/l
1.66
255
1852
69
342
2.18
7.56
1.6
1.5
—
—
—
0
0
263
1990
1.69
7.49
3.1
2.8
—
—
estimate
—
0
0
49
220
2.36
6.77
7.3
4.5
1.85
1.56
%
1.20
49
209
385
3274
1.80
6.77
10.0
8.7
81.41
80.09
u/l
0.28
370
3098
285
2239
1.65
6.73
8.9
7.4
1.20
1.21
mmol/l
1.32
249
1934
156
1061
1.69
6.42
2.3
2.4
—
—
—
0
0
18
48
3.85
6.14
3.3
3.3
3.77
6.79
nmol/l
0.41
18
48
12
18
6.80
5.28
6.7
5.7
—
—
—
0
0
55
299
1.94
4.70
9.1
6.6
25.41
24.59
mmol/l
1.13
55
287
285
2372
1.48
4.31
7.6
7.0
10.63
11.61
umol/l
1.45
275
2268
112
771
1.59
4.19
2.2
1.9
—
—
—
0
0
80
506
1.69
4.18
4.5
4.5
46.99
29.13
ug/l
0.17
71
424
266
2193
1.46
4.16
3.0
2.7
—
—
—
0
0
28
123
2.35
4.11
3.7
3.1
1.19
1.97
index
0.60
16
75
209
1649
1.46
4.09
4.8
4.2
151.27
110.28
e6/l
0.25
158
1196
80
509
1.68
4.09
2.5
3.0
6.62
8.03
umol/l
0.69
70
451
49
269
1.91
4.09
1.9
1.7
—
—
—
0
0
24
103
2.40
3.72
1.2
1.3
—
—
—
0
0
47
266
1.85
3.59
1.4
1.2
172.68
268.32
u/ml
0.60
42
247
188
1482
1.43
3.58
4.2
3.6
546.64
104.32
e6/l
0.44
148
1154
125
929
1.46
3.21
1.8
1.7
1.25
1.36
mg/l
0.17
100
749
24
111
2.22
3.18
1.6
1.5
—
—
—
0
0
93
653
1.52
3.15
2.6
2.7
22.50
22.43
%
0.01
87
616
27
132
2.11
3.13
1.3
1.6
—
—
—
0
0
137
1046
1.43
3.03
2.8
2.8
5.69
4.33
e6/l
0.76
126
960
161
1268
1.40
2.98
4.2
3.4
0.49
0.48
e6/l
0.02
116
946
95
689
1.47
2.74
2.7
2.7
2.34
2.27
g/l
0.63
90
641
70
479
1.54
2.67
3.9
3.3
—
—
—
0
0
24
120
2.05
2.65
1.8
2.2
134.43
126.26
g/l
0.51
14
94
346
3117
1.37
2.59
5.3
4.5
12.68
12.64
mm/h
0.01
330
2886
100
742
1.44
2.56
2.7
2.7
12.99
12.66
umol/l
0.16
95
695
113
861
1.41
2.49
4.9
4.2
111.43
374.68
ng/l
2.09
94
706
97
725
1.42
2.38
4.0
3.3
3.32
1.68
e6/l
0.56
43
374
77
554
1.46
2.32
2.0
1.9
—
—
—
0
0
30
499
0.58
2.29
6.6
7.6
—
—
—
0
0
20
99
2.06
2.29
1.5
1.3
—
—
—
0
0
8
23
3.52
2.28
3.0
4.3
59.88
154.87
nmol/l
—
8
23
173
1429
1.32
2.27
3.3
2.7
55.22
121.29
u/l
0.63
165
1336
19
94
2.06
2.19
1.9
1.9
2.44
3.69
iu/l
—
7
34
80
587
1.43
2.18
2.0
1.9
—
—
—
0
0
14
61
2.33
2.16
4.1
1.9
10.36
10.32
mmol/l
0.01
14
61
178
1488
1.31
2.12
3.5
3.2
1014.09
1432.50
ng/l
1.91
154
1274
0
55
0.00
2.08
0.0
1.1
—
—
—
0
0
101
783
1.36
2.00
3.8
3.1
1.46
1.02
e6/l
0.48
49
430
23
128
1.84
1.93
1.7
1.5
—
—
—
0
0
422
3988
1.40
1.90
24.6
17.5
24.89
24.86
mg/l
0.01
383
3326
18
94
1.95
1.82
1.8
1.5
—
—
—
0
0
13
60
2.20
1.79
1.7
1.6
—
—
—
0
0
31
194
1.64
1.76
2.1
2.3
32.13
39.69
u/l
1.21
25
173
8
31
2.61
1.66
3.4
2.7
0.75
0.94
index
—
8
31
204
1787
1.24
1.56
4.9
4.1
23.62
75.70
ng/l
1.06
153
1347
47
338
1.43
1.46
4.4
3.5
5.15
5.16
kpa
0.02
47
327
5
16
3.15
1.44
1.0
3.7
5.26
4.93
kpa
—
5
16
5
16
3.15
1.44
1.0
3.7
13.72
10.52
kpa
—
5
16
31
206
1.54
1.41
1.2
2.0
1.64
1.45
g/l
0.48
26
187
6
23
2.63
1.37
1.3
2.0
335.50
242.24
mu/l
—
6
17
6
23
2.63
1.37
2.7
1.3
167.33
83.30
ng/l
—
6
23
40
284
1.44
1.34
3.3
3.5
2.29
1.99
mmol/l
0.20
33
210
10
47
2.15
1.34
2.2
1.6
—
—
—
0
0
9
42
2.16
1.34
1.1
1.0
—
—
—
0
0
5
19
2.65
1.22
1.4
2.5
397.80
875.84
u/ml
—
5
19
409
3909
1.27
1.21
22.1
17.1
80.04
77.90
ml/min/173m2
1.44
388
3653
57
440
1.33
1.19
1.8
1.7
1.42
1.55
%
0.91
48
377
6
26
2.32
1.19
1.3
1.9
—
—
—
0
0
108
908
1.24
1.17
3.0
3.1
2.45
2.46
mmol/l
0.08
98
820
0
35
0.00
1.15
0.0
1.2
—
—
—
0
0
0
35
0.00
1.15
0.0
1.2
—
—
—
0
0
21
135
1.58
1.13
1.7
1.6
—
—
—
0
0
7
31
2.28
1.10
1.1
1.5
—
—
—
0
0
5
21
2.39
1.09
1.2
1.1
—
—
—
0
0
5
22
2.29
1.03
1.4
1.7
—
—
—
0
0
5
22
2.29
1.03
1.4
1.7
—
—
—
0
0
5
22
2.29
1.03
1.4
1.7
—
—
—
0
0
5
22
2.29
1.03
1.4
1.7
—
—
—
0
0
16
99
1.64
1.01
1.1
1.5
—
—
—
0
0
19
124
1.55
0.98
2.7
2.2
9.54
13.02
mg/l
1.23
19
115
154
1367
1.18
0.96
2.5
2.2
290.78
266.94
u/l
0.09
147
1299
11
62
1.79
0.95
2.2
1.5
—
—
—
0
0
429
4151
1.26
0.94
27.7
20.8
139.49
139.73
mmol/l
1.05
424
4081
32
235
1.39
0.94
1.2
1.2
29.46
146.04
u/ml
—
9
88
51
406
1.29
0.89
2.4
2.5
41.81
32.70
u/l
0.47
42
341
8
42
1.92
0.89
1.0
1.2
—
—
—
0
0
429
4158
1.24
0.88
27.8
21.0
3.98
3.99
mmol/l
0.74
423
4081
57
464
1.26
0.84
4.6
3.7
0.98
2.06
mmol/l
0.91
47
397
6
31
1.95
0.84
2.2
2.6
13.33
13.33
%
—
6
31
28
374
0.73
0.83
2.2
2.9
92.87
64.39
ml/min/173m2
1.99
16
165
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
138
1.47
0.83
3.8
2.4
0.59
0.36
iu/ml
—
9
70
8
46
1.75
0.83
1.0
1.2
—
—
—
0
0
19
130
1.48
0.82
1.3
1.4
287.73
301.68
ug/g
0.12
11
78
202
1856
1.15
0.79
3.6
3.0
129.15
138.36
ug/l
0.28
194
1729
13
82
1.60
0.78
1.6
2.1
4.87
4.78
mmol/24h
0.04
13
73
168
1525
1.15
0.78
3.9
3.7
2.36
2.35
mmol/l
0.57
154
1375
41
324
1.29
0.78
2.3
1.6
—
—
—
0
0
46
564
0.80
0.74
5.6
5.0
36.04
31.84
%
1.26
27
367
5
25
2.01
0.73
1.2
1.6
—
—
—
0
0
9
57
1.59
0.71
3.3
4.1
—
—
—
0
0
9
57
1.59
0.71
1.0
1.3
0.12
0.18
nmol/l
—
9
40
88
765
1.18
0.71
1.4
1.3
62.85
37.07
iu/ml
0.38
28
241
5
26
1.93
0.71
1.2
1.6
—
—
—
0
0
10
157
0.63
0.70
2.4
1.7
39.70
41.15
nmol/l
—
10
150
5
27
1.86
0.68
1.0
1.3
—
—
—
0
0
5
27
1.86
0.68
1.0
1.3
—
—
—
0
0
89
780
1.17
0.66
4.6
3.3
0.80
0.82
mmol/l
1.04
81
738
291
2766
1.13
0.64
5.8
4.8
23.09
1416.65
e6/l
0.63
11
48
238
2239
1.12
0.61
4.1
4.0
0.00
0.00
estimate
-0.00
62
472
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
2.2
—
—
—
0
0
285
2714
1.12
0.59
3.9
3.5
53.36
54.59
u/l
0.06
271
2539
5
87
0.57
0.56
1.6
1.4
—
—
—
0
0
8
55
1.46
0.56
8.1
5.7
362.13
342.43
umol/l
—
8
49
82
924
0.86
0.56
1.4
1.3
0.61
1.47
u/ml
2.18
25
258
6
37
1.63
0.55
1.0
1.2
—
—
—
0
0
12
82
1.47
0.55
1.2
1.6
—
—
—
0
0
6
38
1.59
0.54
1.0
1.2
—
—
—
0
0
20
260
0.76
0.54
1.5
1.8
—
—
—
0
0
133
1218
1.13
0.54
4.0
3.4
0.00
0.07
estimate
0.60
51
387
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
9
63
1.44
0.52
2.4
1.5
—
—
—
0
0
22
170
1.31
0.52
1.5
3.7
37.20
42.85
mg/l
0.17
17
146
22
170
1.31
0.52
1.5
3.6
92.21
91.72
mg/l
0.00
17
144
238
2255
1.11
0.52
4.1
4.0
0.03
0.00
estimate
0.41
64
485
6
40
1.51
0.51
2.7
2.2
—
—
—
0
0
207
1948
1.11
0.51
2.1
2.2
100.24
94.85
pmol/l
0.86
113
1034
90
1000
0.88
0.51
4.3
4.2
1.02
1.02
kg/l
0.01
60
674
430
4212
1.16
0.50
15.1
12.9
26.67
26.36
u/l
0.13
422
4100
142
1316
1.11
0.47
1.7
1.7
18.67
20.33
nmol/l
0.80
123
1103
85
764
1.14
0.47
1.9
1.7
1111.08
1166.19
nmol/l
0.27
64
588
18
231
0.77
0.46
1.6
1.7
—
—
—
0
0
23
183
1.27
0.45
1.4
1.5
0.45
0.31
mg/l
—
10
84
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
319
3088
1.09
0.41
4.5
4.2
14.91
14.88
pmol/l
0.08
291
2794
0
17
0.00
0.40
0.0
1.1
—
9.10
—
0
17
120
1114
1.10
0.39
2.5
2.2
2.89
2.98
mg/l
0.15
106
966
9
66
1.37
0.38
1.1
1.3
0.54
0.56
nmol/l
—
9
61
5
36
1.39
0.38
1.2
1.5
—
—
—
0
0
9
124
0.72
0.35
1.9
1.7
241.11
221.64
pmol/l
—
9
114
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
63
568
1.13
0.35
1.5
1.4
—
—
—
0
0
28
238
1.19
0.33
1.7
1.4
—
—
—
0
0
399
4060
0.91
0.33
6.2
6.2
2.64
2.64
mmol/l
0.00
374
3749
124
1164
1.09
0.32
2.9
2.9
341.08
353.90
umol/l
0.80
112
1031
6
47
1.28
0.32
1.0
1.2
—
—
—
0
0
237
2283
1.07
0.32
4.3
4.0
0.00
0.69
estimate
0.51
55
446
7
96
0.73
0.31
1.1
1.2
5.43
1347.96
e6/l
—
7
75
11
84
1.32
0.30
1.6
3.6
5.72
9.94
pmol/l
2.06
11
84
13
102
1.28
0.30
1.7
1.6
—
—
—
0
0
19
157
1.22
0.30
1.4
3.3
1.12
2.78
ratio
—
7
88
32
365
0.87
0.29
2.3
2.0
3.96
3.57
ratio
0.95
24
305
401
3944
1.09
0.29
5.6
5.5
6.04
6.05
mmol/l
0.05
366
3609
7
57
1.23
0.29
1.0
1.1
—
23.40
—
0
10
8
62
1.30
0.28
1.1
1.4
—
—
—
0
0
194
1864
1.07
0.27
2.9
2.5
77.23
77.43
nmol/l
0.03
176
1666
186
1789
1.06
0.25
1.9
2.0
1.47
1.35
mmol/l
0.95
140
1488
391
3969
0.93
0.25
5.3
5.4
1.41
1.44
mmol/l
0.85
364
3658
17
142
1.20
0.25
2.3
1.8
2.35
3.08
mg/l
0.41
17
114
10
126
0.79
0.24
1.1
1.3
—
—
—
0
0
377
3708
1.07
0.24
5.8
5.2
1.87
1.98
mu/l
0.81
351
3368
16
134
1.20
0.23
1.1
1.2
—
—
—
0
0
162
1557
1.06
0.23
3.6
3.4
7.46
7.70
mmol/l
0.29
135
1302
7
94
0.74
0.22
1.1
1.2
1.86
17.99
e6/l
—
7
72
10
79
1.27
0.22
1.3
1.5
—
—
—
0
0
10
79
1.27
0.22
1.3
1.5
—
—
—
0
0
133
1272
1.06
0.22
4.4
4.1
0.00
0.00
estimate
0.50
56
436
5
42
1.19
0.21
1.4
1.6
—
—
—
0
0
5
42
1.19
0.21
1.4
1.6
—
—
—
0
0
5
42
1.19
0.21
1.4
1.6
—
—
—
0
0
86
911
0.93
0.21
2.2
1.8
399.03
20577106.56
pmol/l
0.69
73
763
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
8
102
0.78
0.21
1.0
1.1
—
10.77
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
19
164
1.16
0.20
3.4
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
9
111
0.81
0.20
1.2
1.2
—
—
—
0
0
6
49
1.23
0.20
1.0
1.3
—
—
—
0
0
23
260
0.88
0.20
3.8
3.7
42.82
48.07
%
0.58
23
253
394
3987
0.94
0.19
5.4
5.5
4.51
4.55
mmol/l
0.23
370
3698
34
309
1.11
0.19
4.1
2.9
129.59
129.49
g/l
0.01
34
301
6
53
1.13
0.18
1.0
1.8
—
—
—
0
0
21
186
1.13
0.17
2.0
1.9
1031.71
516.66
ug/l
0.25
21
178
17
194
0.87
0.17
1.6
2.2
3.13
3.02
g/l
0.17
17
180
50
468
1.08
0.16
1.3
1.5
—
—
—
0
0
377
3811
0.95
0.14
4.5
4.6
1.32
1.30
mmol/l
0.26
347
3485
15
170
0.88
0.14
1.3
1.4
—
—
—
0
0
75
717
1.05
0.13
1.3
1.3
14.85
15.17
u/ml
0.02
23
281
15
132
1.14
0.13
1.6
1.6
0.00
0.12
iu/ml
—
6
27
147
1430
1.04
0.13
4.3
4.7
20.32
21.50
%
0.48
73
712
10
86
1.17
0.11
2.3
1.7
—
—
—
0
0
384
3871
0.96
0.10
7.0
7.0
40.35
39.94
mmol/mol
0.35
357
3626
5
45
1.11
0.10
1.2
1.1
—
—
—
0
0
158
1548
1.03
0.09
4.3
4.2
6.53
8.38
mg/mmol
0.36
104
975
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
16
175
0.91
0.08
1.5
2.1
8.47
10.69
g/l
2.26
16
160
19
175
1.09
0.08
3.1
4.0
25.30
25.18
mmol/l
0.06
19
162
179
1760
1.03
0.08
5.1
5.7
2.03
3.17
ug/l
1.64
163
1582
5
61
0.82
0.08
1.0
1.5
—
—
—
0
0
5
60
0.83
0.08
1.0
1.5
—
—
—
0
0
5
60
0.83
0.08
1.0
1.5
—
—
—
0
0
10
112
0.89
0.07
1.2
1.2
—
—
—
0
0
7
85
0.82
0.07
1.0
2.2
—
—
—
0
0
17
157
1.09
0.07
3.5
1.7
—
—
—
0
0
13
118
1.10
0.07
1.4
1.2
—
—
—
0
0
40
384
1.05
0.06
2.4
2.7
7.64
8.19
ug/l
0.09
35
341
19
203
0.93
0.06
1.5
2.2
3.54
3.68
g/l
0.25
19
189
19
203
0.93
0.06
1.5
2.2
7.81
7.39
g/l
0.36
19
189
19
203
0.93
0.06
1.5
2.2
4.12
4.22
g/l
0.24
19
189
11
121
0.91
0.06
1.4
1.6
—
—
—
0
0
432
4303
1.03
0.05
35.0
26.5
250.42
244.60
e9/l
1.07
425
4229
432
4303
1.03
0.05
34.9
26.5
4.49
4.47
e12/l
0.30
424
4215
15
139
1.08
0.05
1.0
1.3
—
—
—
0
0
12
110
1.09
0.05
1.3
1.3
—
—
—
0
0
108
1066
1.02
0.03
2.9
3.3
0.60
0.78
ug/l
2.75
76
705
10
107
0.93
0.02
1.0
1.1
1.45
1.54
g/l
—
10
107
12
113
1.06
0.02
1.1
1.2
0.89
0.90
g/l
0.04
12
113
172
1710
1.01
0.01
4.3
3.9
0.00
0.04
estimate
1.71
52
397
19
183
1.04
0.01
1.8
1.7
1.68
8.50
iu/ml
—
5
48
14
134
1.05
0.00
3.4
3.1
1.79
1.61
mmol/l
0.59
14
128
15
156
0.96
0.00
1.5
1.5
8.04
11.88
u/ml
—
5
27
13
125
1.04
0.00
1.0
1.7
—
—
—
0
0
14
144
0.97
0.00
1.6
2.2
0.00
0.00
g/l
-0.00
14
136
26
264
0.98
0.00
2.2
1.7
3.73
3.50
mmol/l
0.42
18
202
19
187
1.02
0.00
1.0
1.1
—
—
—
0
0
11
108
1.02
0.00
3.8
3.2
8.05
7.60
mmol/l
0.22
11
103
10
101
0.99
0.00
1.5
2.2
—
—
—
0
0
6
61
0.98
0.00
1.2
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
8.1
—
5.52
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
14.48
—
0
5
6
63
0.95
-0.00
1.2
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
1.19
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
10
100
1.00
-0.00
1.9
1.8
—
—
—
0
0
6
63
0.95
-0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
97
0.93
-0.00
1.3
1.4
1.02
0.86
nmol/l
—
9
82
0
5
0.00
-0.00
0.0
11.2
—
34.60
—
0
5
5
53
0.94
-0.00
1.2
1.2
7.10
7.91
mmol/l
—
5
42
5
51
0.98
-0.00
1.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
91
0.99
-0.00
1.4
1.5
—
—
—
0
0
8
79
1.01
-0.00
4.9
3.6
—
3554.62
—
0
8
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRONCHUS_LUNG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRONCHUS_LUNG | 1.748 [1.41, 2.17] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.142 |
During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 715 females with CD2_BENIGN_BRONCHUS_LUNG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRONCHUS_LUNG | 1.92 [1.6, 2.3] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.072 |
During the follow-up period (1.1.1998 — 31.12.2019), 241 out of 829 males with CD2_BENIGN_BRONCHUS_LUNG died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRONCHUS_LUNG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.359% |
| 5 | 0.91% | 2.593% |
| 10 | 2.427% | 6.229% |
| 15 | 4.365% | 11.649% |
| 20 | 8.005% | 19.781% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRONCHUS_LUNG – Benign neoplasm: Bronchus and lung
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data