pulmonary edema: Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
831 |
4. Check minimum number of eventsNone |
831 |
5. Include endpointsNone |
831 |
6. Filter based on genotype QC (FinnGen only) |
701 |
Control definitions (FinnGen only)
- Control exclude
- J10_INTERSTITIUM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF6
- Parent code in ICD-10
- J80-J84
- Name in latin
- Oedema pulmonum
Similar endpoints
↥List of similar endpoints to
Pulmonary oedema
based on the number of shared cases.
Similar with more cases:
- Other respiratory diseases principally affecting the interstitium
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9006 | 4604 | 4219 |
| Only index persons | 5204 | 2779 | 2425 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.13 | 0.12 |
| Only index persons | 0.10 | 0.10 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 77.49 | 80.34 | 74.43 |
| Only index persons | 76.85 | 79.98 | 73.26 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 701 | 264 | 437 |
| Unadjusted period prevalence (%) | 0.16 | 0.09 | 0.20 |
| Median age at first event (years) | 74.14 | 74.57 | 73.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 740
- Matched controls
- 7396
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J81
ICD-10 Finland
Pulmonary oedema
+∞
307.7
740
*
I50.0
ICD-10 Finland
Congestive heart failure
6.9
139.0
295
647
I50.9
ICD-10 Finland
Heart failure, unspecified
5.7
123.4
412
1337
C03CA01
ATC
furosemide; systemic
7.0
114.8
594
2729
I50.1
ICD-10 Finland
Left ventricular failure
7.1
106.8
191
345
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.0
97.0
309
932
WX722
NOMESCO Finland
PEEP
7.8
79.5
121
181
TK800
NOMESCO Finland
Hemodialysis
13.8
78.0
75
60
Z49.1
ICD-10 Finland
Extracorporeal dialysis
16.6
69.8
60
39
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
10.0
67.5
81
90
WX872
NOMESCO Finland
Intensive care
6.7
63.3
109
185
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
9.7
61.5
75
85
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
17.6
57.8
48
29
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.3
51.6
156
431
C03DA01
ATC
spironolactone; oral
3.6
50.3
211
732
J96.0
ICD-10 Finland
Acute respiratory failure
11.6
47.3
50
46
N18.8
ICD-10 Finland
Other chronic renal failure
7.5
45.6
68
98
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.0
45.6
365
1833
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.9
44.6
154
465
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.0
44.0
306
1418
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
18.0
43.9
36
21
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.8
40.3
98
226
A11CC03
ATC
alfacalcidol; systemic
7.2
40.0
62
93
C01DA14
ATC
isosorbide mononitrate; oral
2.8
38.1
298
1447
N18.0
ICD-10 Finland
End-stage renal disease
11.1
37.8
41
39
WX730
NOMESCO Finland
Conventional respirator
9.5
37.2
45
50
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
37.2
361
1948
WX882
NOMESCO Finland
High dependency care
6.2
34.6
62
108
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
3.6
34.5
128
402
103
Kela drug reimbursment
Diabetes, insulin-treated
2.6
33.4
319
1686
A12AA04
ATC
calcium carbonate; oral
8.4
33.1
44
55
V03AE01
ATC
polystyrene sulfonate; oral
8.3
32.7
44
56
AN1
HP
Coronary angiography
3.0
32.6
176
694
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
32.6
233
1067
L04AA06
ATC
mycophenolic acid; systemic
11.9
32.0
33
29
I25.2
ICD-10 Finland
Old myocardial infarction
3.2
31.8
146
523
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
31.7
151
553
ZXD05
NOMESCO Finland
Urgent procedure
2.5
31.0
295
1544
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.7
30.9
111
340
C07AB07
ATC
bisoprolol; oral
2.6
30.8
505
3377
B03XA02
ATC
darbepoetin alfa; parenteral
6.7
30.7
50
79
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.1
29.6
34
35
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
28.0
228
1101
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.4
27.9
288
1550
WX892
NOMESCO Finland
Monitored bed care
3.6
27.3
101
315
A10AB05
ATC
insulin aspart; parenteral
3.5
26.9
102
323
A10AE04
ATC
insulin glargine; parenteral
3.1
26.8
129
473
205
Kela drug reimbursment
Chronic hypertension
2.3
26.4
343
2026
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.6
26.3
66
155
A10AC01
ATC
insulin (human); parenteral
3.2
25.8
118
419
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.3
25.5
284
1567
R06.0
ICD-10 Finland
Dyspnoea
2.3
25.0
273
1490
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.5
24.9
50
97
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
3.7
24.7
86
257
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
23.1
150
643
A10AB01
ATC
insulin (human); parenteral
4.8
23.0
54
120
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
6.5
22.9
38
61
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
22.8
192
930
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.5
22.5
181
859
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
3.9
22.4
70
194
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
6.9
22.3
35
53
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.6
22.1
156
695
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.6
22.1
76
225
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
21.9
168
779
C01AA05
ATC
digoxin; systemic
2.5
21.8
166
766
C01BD01
ATC
amiodarone; systemic
4.9
21.5
49
106
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.8
21.2
67
187
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.1
21.1
307
1854
ZX120
NOMESCO Finland
Intravenous
2.9
20.7
106
400
A12BA01
ATC
potassium chloride; oral
3.1
20.6
96
343
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
20.4
140
614
A10AE05
ATC
insulin detemir; parenteral
3.7
20.4
68
197
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
20.3
300
1817
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.2
20.1
35
59
B01AA03
ATC
warfarin; systemic
2.1
20.0
271
1585
C09AA05
ATC
ramipril; oral
2.1
19.9
278
1645
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
3.8
19.6
63
178
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.3
19.6
79
259
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
3.6
19.3
66
194
WX725
NOMESCO Finland
Noninvasive ventilation
3.7
19.1
64
186
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
18.9
103
401
A10AA02, ,
ATC
3.8
18.5
60
170
Z94.0
ICD-10 Finland
Kidney transplant status
22.4
18.3
26
12
127
Kela drug reimbursment
Transplant complication
14.8
18.2
30
21
A10BA02
ATC
metformin; oral
2.0
17.9
280
1712
A10AA01, ,
ATC
5.4
17.8
36
70
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
17.8
215
1195
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.9
17.8
55
151
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
17.8
133
605
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
184.1
17.6
18
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
17.4
17.5
27
16
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
24.7
17.4
24
10
A10BB12
ATC
glimepiride; oral
2.6
17.3
111
469
B01AC04
ATC
clopidogrel; oral
2.1
17.2
197
1071
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
5.7
17.1
32
58
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.6
16.9
58
171
M04AA01
ATC
allopurinol; systemic
2.2
16.9
174
907
C08CA01
ATC
amlodipine; oral
1.9
16.8
358
2420
Z49.0
ICD-10 Finland
Preparatory care for dialysis
13.1
16.8
29
23
C08CA02
ATC
felodipine; oral
2.4
16.6
124
562
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.6
16.6
109
465
WX704
NOMESCO Finland
Intubation
3.1
16.5
74
258
C02AC05
ATC
moxonidine; oral
3.3
16.5
66
215
C09AA02
ATC
enalapril; systemic
2.0
16.4
221
1274
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
16.4
234
1378
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
16.3
59
180
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.8
16.0
37
81
XCK10
NOMESCO Finland
Photography of fundus of eye
2.5
15.9
106
456
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
4.3
15.8
42
103
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.6
15.7
101
426
J80
ICD-10 Finland
Adult respiratory distress syndrome
+∞
15.7
15
*
V03AE02
ATC
sevelamer; oral
26.9
15.7
21
8
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.4
15.6
116
524
TK810
NOMESCO Finland
Hemofiltration
22.6
15.6
22
10
L04AD02
ATC
tacrolimus; systemic
22.6
15.6
22
10
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
15.3
216
1261
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.1
14.8
42
108
196
Kela drug reimbursment
Paricalcitol and cinacalcet
21.6
14.7
21
10
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
14.7
134
661
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
2.9
14.6
73
270
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
14.6
393
2821
I50
ICD-10 Finland
Heart failure
3.2
14.5
60
199
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.5
14.5
98
424
A10BB01
ATC
glibenclamide; oral
2.7
14.3
83
333
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
22.8
14.3
20
9
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
14.2
72
269
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.8
14.0
75
288
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.6
13.9
47
137
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.1
13.8
38
96
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.9
13.7
41
110
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
76.5
13.6
15
*
WW500
NOMESCO Finland
Blood transfusion
3.2
13.4
56
187
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.3
13.3
34
81
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
5.4
13.0
26
50
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.0
12.9
57
197
N17.8
ICD-10 Finland
Other acute renal failure
5.9
12.8
23
40
I20.09
ICD-10 Finland
Unstable angina
2.5
12.4
85
369
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
12.4
81
344
C07AB02
ATC
metoprolol; systemic
1.8
12.3
225
1417
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
12.2
63
237
A46
ICD-10 Finland
Erysipelas
2.0
12.2
147
804
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
12.1
124
639
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.4
12.1
24
46
1CX08, ,
NOMESCO Finland
21.7
12.0
17
8
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.1
12.0
51
172
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
5.1
12.0
25
50
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
12.0
286
1947
137
Kela drug reimbursment
Uraemia requiring dialysis
12.0
11.9
21
18
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
11.8
117
595
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
19.3
11.6
17
9
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
11.3
11.6
21
19
A10AD05
ATC
insulin aspart; parenteral
3.7
11.6
37
104
WX203
NOMESCO Finland
Infraclavicular plexus blockade
5.1
11.5
24
48
H05BX01
ATC
cinacalcet; oral
13.9
11.5
19
14
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
13.9
11.5
19
14
I47.2
ICD-10 Finland
Ventricular tachycardia
4.0
11.4
32
82
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
35.6
11.3
14
*
H3603, E103,
ICD-10 Finland
35.6
11.3
14
*
V03AE03
ATC
lanthanum carbonate; oral
20.4
11.2
16
8
A10BH05
ATC
linagliptin; oral
2.6
11.1
67
273
NHQ40
NOMESCO Finland
Amputation of toe
4.4
11.1
28
66
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.6
11.0
37
108
SPAT1262
SPAT
Handing over of treatment supplies
1.9
10.9
149
849
C10AA01
ATC
simvastatin; oral
1.7
10.9
387
2914
C09BA02
ATC
enalapril and diuretics; systemic
2.3
10.8
91
433
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.3
10.7
41
130
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.0
10.7
47
162
A07AA09
ATC
vancomycin; oral
5.4
10.6
21
40
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
5.1
10.6
22
44
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
10.2
10.6
20
20
N19
ICD-10 Finland
Unspecified kidney failure
2.7
10.5
58
226
L04AX01
ATC
azathioprine; systemic
3.6
10.4
34
97
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.5
10.3
25
57
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
10.3
130
721
Z49.2
ICD-10 Finland
Other dialysis
13.3
10.2
17
13
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.8
10.1
31
85
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
4.9
10.1
22
46
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.4
10.0
72
319
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.9
10.0
29
76
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.5
10.0
63
263
AP1
HP
Catheterization of the left side of the heart
4.0
9.9
28
72
Z3231
NOMESCO Finland
Registered nurse
1.7
9.9
212
1385
J01FF01
ATC
clindamycin; systemic
1.8
9.7
191
1218
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.3
9.6
72
325
I21.4
ICD-10 Finland
Acute subendocardial myocardial infarction
4.0
9.5
27
70
K77
ICPC
Heart failure
3.1
9.3
39
131
WX890
NOMESCO Finland
Intesive care monitoring
7.4
9.3
21
29
J01MA14
ATC
moxifloxacin; systemic
2.3
9.2
76
358
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
9.2
49
188
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.2
9.2
36
116
WW200, ,
SPAT
0.4
9.2
59
1239
I21.09
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
3.5
9.1
31
91
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
3.9
9.1
27
72
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.9
9.1
44
160
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
11.6
9.1
16
14
I21.9
ICD-10 Finland
Acute myocardial infarction, unspecified
2.8
9.1
45
166
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
37.1
9.0
11
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.6
9.0
29
82
E87.5
ICD-10 Finland
Hyperkalaemia
3.3
9.0
33
102
B05DB
ATC
Hypertonic solutions
12.7
8.9
15
12
AA1
HP
Conventional CABG
3.2
8.9
34
108
C09AA01
ATC
captopril; oral
3.4
8.8
32
98
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
10.9
8.8
16
15
81
HP
Angiography of the heart and coronary arteries
2.1
8.8
88
448
M01AH05
ATC
etoricoxib; oral
0.6
8.8
188
2706
C02EA02, ,
ATC
2.4
8.8
64
286
250, ,
Kela drug reimbursment
3.6
8.7
28
79
N18
ICD-10 Finland
Chronic kidney disease
4.8
8.6
19
40
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.7
8.6
27
75
B05DA
ATC
Isotonic solutions
11.7
8.6
15
13
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
16.5
8.6
13
8
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
2.8
8.5
43
160
R50.9
ICD-10 Finland
Fever, unspecified
1.9
8.5
118
673
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
20.3
8.5
12
6
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.1
8.5
87
447
A10AD01
ATC
insulin (human); parenteral
3.4
8.4
30
91
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.3
8.4
65
298
H3600, E113,
ICD-10 Finland
4.7
8.4
19
41
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.1
8.4
88
456
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
8.3
176
1139
A98
ICPC
Health maint/preventive medicine
0.6
8.3
448
5248
S97
ICPC
Chronic ulcer skin
2.2
8.3
68
319
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
3.5
8.3
28
82
A10BH01
ATC
sitagliptin; oral
2.0
8.2
88
459
WW200
NOMESCO Finland
Immunization
4.0
8.2
23
59
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
7.7
8.2
18
24
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
8.2
64
295
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.2
8.0
31
99
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
22.3
8.0
11
5
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
22.3
8.0
11
5
207
Kela drug reimbursment
Chronic arrhythmias
1.7
8.0
169
1092
K65.0
ICD-10 Finland
Acute peritonitis
4.5
7.9
19
43
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.3
7.9
29
90
AN2
HP
Balloon angioplasty, including several vessels
3.0
7.8
35
122
XF404
NOMESCO Finland
Ambulatory ECG
2.1
7.8
80
410
Z2221
NOMESCO Finland
Medical doctor
1.7
7.8
188
1259
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.9
7.7
103
579
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
45.4
7.7
9
*
J96.1
ICD-10 Finland
Chronic respiratory failure
3.1
7.7
31
102
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.0
7.6
21
53
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
12.0
7.6
13
11
C10AA05
ATC
atorvastatin; oral
1.5
7.5
323
2471
R4110
NOMESCO Finland
Physiotherapy
1.6
7.5
192
1302
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.5
7.5
18
41
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
3.8
7.4
22
59
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
2.8
7.4
36
132
C08DB01
ATC
diltiazem; oral
2.1
7.3
74
378
321
Kela drug reimbursment
Paricalcitol and cinacalcet
9.5
7.3
14
15
M10.3
ICD-10 Finland
Gout due to impairment of renal function
9.5
7.3
14
15
R41.0
ICD-10 Finland
Disorientation, unspecified
2.6
7.3
43
174
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.9
7.3
21
55
T90
ICPC
Diabetes non-insulin dependent
1.6
7.3
185
1252
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.9
7.3
19
33
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
3.6
7.2
23
65
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
20.2
7.1
10
5
A10AB04
ATC
insulin lispro; parenteral
3.4
7.0
25
76
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
7.0
125
769
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
2.9
7.0
33
119
I21.01
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
3.8
6.9
21
57
H3601, E103,
ICD-10 Finland
13.9
6.9
11
8
SPAT1255
SPAT
Intravenous administration of medicine
2.2
6.9
60
289
I21.00
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
3.2
6.9
26
82
J01MA12
ATC
levofloxacin; systemic
1.7
6.9
156
1024
PE1AT
NOMESCO Finland
Femoral artery PTA
3.8
6.8
20
53
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
6.8
53
244
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.2
6.8
56
264
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
6.8
52
238
FXG00
NOMESCO Finland
Insertion and use of IABP
16.9
6.8
10
6
H3601, E113,
ICD-10 Finland
3.5
6.7
23
68
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.7
6.7
35
133
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
7.3
6.7
15
21
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.2
6.7
58
279
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
22.7
6.7
9
*
AN3
HP
Balloon angioplasty and metallic stent
2.7
6.6
35
134
H02AB06
ATC
prednisolone; systemic
1.5
6.6
331
2598
3AC01, ,
NOMESCO Finland
6.9
6.5
15
22
C07AB03
ATC
atenolol; systemic
2.0
6.3
70
369
ZXE90
NOMESCO Finland
More than 22 hours
6.0
6.3
16
27
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
6.3
105
1643
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.3
483
4113
11
HP
Coronary artery bypass surgery
2.6
6.3
36
144
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
6.2
29
104
Z3226
NOMESCO Finland
Physiotherapist
1.7
6.2
132
851
I81
ICD-10 Finland
Portal vein thrombosis
7.8
6.1
13
17
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
6.1
203
1455
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.1
63
324
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
6.1
120
757
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
6.1
36
146
WW502
NOMESCO Finland
Autotransfusion
8.7
6.1
12
14
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
10.1
6.0
11
11
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.0
208
1503
H04AA01
ATC
glucagon; nasal, parenteral
6.1
6.0
15
25
CKC15
NOMESCO Finland
Panretinal photocoagulation
5.6
6.0
16
29
B03XA01
ATC
erythropoietin; parenteral
3.9
6.0
17
44
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.9
6.0
17
44
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.0
6.0
68
362
C03AA03
ATC
hydrochlorothiazide; oral
1.8
6.0
88
510
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
211
626
4.31
64.48
20.6
6.2
15.00
11.69
mmol/l
6.33
204
594
234
807
3.78
57.05
14.5
6.5
5.25
5.11
kpa
0.88
222
772
233
808
3.75
56.25
14.6
6.5
10.13
11.49
kpa
4.85
220
773
232
804
3.74
56.04
14.4
6.5
1.76
1.18
mmol/l
0.96
183
644
241
895
3.51
51.85
19.2
5.0
1.19
1.04
mmol/l
7.36
233
826
205
736
3.47
45.88
14.6
6.6
93.47
94.99
%
2.09
196
707
245
1044
3.01
40.44
5.7
3.2
0.83
0.82
mmol/l
1.21
236
980
187
728
3.10
35.70
9.5
3.5
1.94
1.94
mmol/l
0.01
160
595
187
749
3.00
33.77
9.6
3.5
5.83
5.80
kpa
0.15
176
723
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
94
243
4.28
33.30
4.3
2.5
0.29
0.34
iu/ml
0.79
60
137
234
1087
2.68
31.67
7.1
2.5
2.16
2.23
g/l
0.93
220
996
222
1005
2.73
31.62
7.3
2.5
20.50
21.27
%
0.27
213
930
115
369
3.50
29.82
21.9
8.3
14.91
15.69
%
1.79
110
354
237
1156
2.54
28.58
7.3
2.5
10.62
11.71
umol/l
0.89
228
1070
50
87
6.09
27.90
9.5
5.1
388.00
310.22
iu/ml
—
15
9
152
619
2.83
26.05
5.8
3.4
538.31
266.24
ng/l
4.89
141
576
132
500
2.99
25.81
9.6
3.7
192.09
96.45
ng/l
3.05
121
425
116
412
3.15
25.34
12.3
8.5
24.17
24.51
mmol/l
0.38
110
401
92
301
3.35
22.93
3.3
1.8
6.20
2.61
ug/l
0.44
86
252
118
449
2.94
22.74
7.2
2.9
112.35
125.73
g/l
7.92
113
435
190
922
2.43
22.46
2.3
1.8
—
—
—
0
0
178
867
2.39
20.68
2.5
1.8
—
—
—
0
0
227
1226
2.23
20.67
2.6
1.9
—
—
—
0
0
88
300
3.19
20.45
17.7
3.8
0.86
0.89
%
0.31
81
280
56
142
4.18
20.18
22.4
4.8
104.44
104.77
mmol/l
0.14
50
128
56
142
4.18
20.18
22.3
4.8
11.52
11.41
mmol/l
0.06
50
128
142
630
2.55
20.17
6.8
2.9
5.28
4.33
kpa
3.80
132
608
91
320
3.10
20.06
17.2
3.8
1.78
1.57
%
2.43
82
300
98
365
2.94
19.52
2.4
1.8
1.56
1.57
g/l
0.04
88
328
195
1013
2.25
19.35
3.9
2.0
30.74
29.84
s
1.34
188
977
53
134
4.18
19.17
1.6
1.4
—
—
—
0
0
234
1315
2.14
19.02
8.9
4.5
315.83
273.45
ng/l
0.20
214
1151
119
509
2.59
18.13
2.2
1.7
—
—
—
0
0
62
186
3.54
17.61
4.2
2.5
7.44
7.82
kpa
1.07
62
181
92
350
2.86
17.58
7.4
3.2
24.52
25.07
mmol/l
0.56
87
337
164
825
2.27
17.39
5.5
4.0
261.05
247.58
u/l
0.70
155
781
108
456
2.60
16.84
7.6
3.5
5.17
5.14
kpa
0.13
108
433
22
8
28.26
16.57
15.5
12.4
5.20
5.74
mmol/l
—
22
8
51
142
3.78
16.15
1.5
1.5
—
—
—
0
0
58
181
3.39
15.50
6.3
2.3
2.54
1.84
mg/l
4.67
53
157
93
390
2.58
14.64
7.7
3.5
1.65
2.01
mmol/l
0.39
73
282
137
695
2.19
14.00
5.5
2.4
78.05
66.77
e9/l
2.35
103
533
43
123
3.65
13.11
1.6
1.3
—
—
—
0
0
29
62
4.82
12.91
1.6
1.6
—
—
—
0
0
121
605
2.19
12.76
4.0
2.7
6.16
6.01
ug/l
0.05
112
520
328
2308
1.76
12.31
6.8
3.5
5467.40
2162.03
ng/l
7.75
305
2028
17
8
21.70
12.04
7.8
7.4
5.72
4.80
kpa
—
17
8
30
70
4.42
12.03
2.5
1.4
169.38
156.65
au/ml
0.26
13
16
53
189
2.94
11.34
1.9
1.5
—
—
—
0
0
37
107
3.59
11.11
1.8
1.3
—
—
—
0
0
33
91
3.75
10.62
1.5
1.4
—
—
—
0
0
40
126
3.30
10.55
1.5
1.5
26.50
29.37
g/l
0.78
34
117
63
256
2.60
10.54
4.5
3.9
89.45
79.72
mg/l
0.16
51
222
63
257
2.58
10.46
4.5
3.9
67.28
51.21
mg/l
0.60
51
226
37
112
3.42
10.38
10.1
2.9
26.30
10.65
pmol/l
1.50
37
112
59
234
2.65
10.36
4.7
3.6
1.67
2.79
ratio
1.32
33
144
115
613
2.04
10.16
3.2
2.8
64.29
65.78
g/l
1.12
106
553
29
76
3.93
10.02
1.8
1.1
283.43
298.84
u/ml
0.07
21
38
258
1778
1.69
9.91
3.4
2.3
3.11
3.09
mg/l
0.03
240
1506
35
106
3.41
9.82
1.5
1.4
—
—
—
0
0
53
210
2.64
9.33
4.3
3.5
0.88
0.84
nmol/l
0.27
42
173
120
672
1.94
9.18
4.3
2.9
7.55
9.23
umol/l
0.86
103
593
58
243
2.50
9.12
1.9
1.3
—
—
—
0
0
184
1180
1.74
9.07
3.2
1.7
1.67
1.55
mg/l
0.24
158
954
29
82
3.64
9.02
1.2
1.2
—
—
—
0
0
13
7
18.86
8.95
8.5
7.6
9.28
11.03
%
—
13
7
109
601
1.95
8.71
2.8
2.2
0.19
0.20
g/l
0.29
101
545
401
3156
1.59
8.66
32.3
19.9
1.46
1.38
inr
1.53
360
2679
18
37
4.96
8.39
1.1
1.1
—
—
—
0
0
17
20
8.67
8.33
2.9
1.6
0.61
0.62
mmol/l
0.20
17
20
30
92
3.35
8.28
1.3
1.3
—
—
—
0
0
41
153
2.78
8.12
1.5
1.3
—
—
—
0
0
323
2443
1.57
8.11
6.9
3.0
238.47
153.03
ug/l
2.91
310
2227
33
109
3.12
8.09
1.6
1.3
607.64
1396.16
e6/l
1.97
22
75
46
183
2.61
8.05
2.0
1.5
1.98
8.12
iu/ml
1.74
12
48
30
94
3.28
8.01
1.6
1.3
31446.94
25770.81
e6/l
0.15
18
53
13
10
13.20
7.89
1.0
1.0
—
—
—
0
0
396
3149
1.55
7.87
28.3
7.0
1.18
1.21
mmol/l
11.15
361
2682
398
4762
0.64
7.84
48.5
20.1
56.57
71.25
ml/min/173m2
20.70
382
4475
29
91
3.27
7.73
1.4
1.7
—
—
—
0
0
24
68
3.61
7.46
1.4
1.5
—
—
—
0
0
466
5362
0.65
7.27
72.7
30.0
4.08
4.36
e12/l
19.23
458
5221
466
5361
0.65
7.25
72.9
30.0
233.56
237.24
e9/l
0.50
459
5240
56
259
2.26
7.09
2.9
2.6
10.46
10.59
g/l
0.07
48
226
14
17
8.37
6.84
3.4
2.1
84.86
98.24
%
0.55
14
17
353
2806
1.49
6.60
14.0
4.9
31.84
34.45
g/l
13.68
341
2598
37
148
2.58
6.44
1.5
1.2
—
—
—
0
0
37
148
2.58
6.44
1.5
1.2
—
—
—
0
0
354
2826
1.48
6.42
24.7
6.3
1.18
1.21
mmol/l
10.90
335
2574
466
5318
0.66
6.39
62.7
27.0
140.69
86.78
umol/l
16.14
459
5231
30
109
2.82
6.28
1.5
1.4
—
—
—
0
0
402
4713
0.68
6.25
6.3
5.2
1.23
1.42
mmol/l
17.01
375
4243
44
195
2.33
6.17
1.5
2.0
33.19
38.69
u/l
0.86
37
170
70
373
1.97
6.16
2.0
1.5
—
—
—
0
0
456
5210
0.67
6.09
23.1
12.5
27.70
24.44
u/l
1.33
443
5020
84
478
1.85
6.07
2.2
1.7
—
—
—
0
0
58
296
2.04
5.76
2.8
2.5
4.04
3.71
g/l
0.75
51
265
58
297
2.03
5.71
2.8
2.5
4.28
4.12
g/l
0.68
51
265
58
297
2.03
5.71
2.8
2.5
7.98
7.55
g/l
0.88
51
265
410
4754
0.69
5.67
6.4
5.3
3.93
4.35
mmol/l
14.12
383
4321
55
277
2.06
5.66
2.9
2.6
3.15
3.08
g/l
0.16
48
245
210
1539
1.51
5.65
5.0
2.9
421.23
364.78
umol/l
8.09
196
1322
12
16
7.60
5.64
1.1
1.1
—
—
—
0
0
423
4875
0.69
5.63
7.1
6.1
2.14
2.47
mmol/l
13.29
397
4404
419
4837
0.69
5.63
6.8
5.6
6.59
6.13
mmol/l
5.20
376
4327
231
1732
1.48
5.55
4.6
3.0
44.08
35.46
u/l
0.44
221
1637
138
1953
0.64
5.29
3.6
5.0
24.01
21.65
%
0.85
65
1038
12
18
6.75
5.26
2.1
1.8
10351.67
84083.00
e6/l
—
6
13
241
1839
1.46
5.24
4.9
2.6
63.56
105.02
u/l
0.46
230
1712
466
5247
0.70
5.12
71.2
25.1
4.09
4.02
mmol/l
4.89
461
5131
16
45
3.61
5.06
1.4
1.3
—
—
—
0
0
466
5242
0.70
5.04
69.2
24.8
138.93
139.53
mmol/l
4.29
460
5129
86
523
1.73
4.99
3.4
2.6
135.84
34.02
u/l
0.49
75
441
15
41
3.71
4.94
1.2
1.5
—
—
—
0
0
371
3091
1.40
4.84
10.0
6.4
12.69
12.54
umol/l
0.07
361
2944
93
1412
0.61
4.78
2.3
3.5
1.02
0.84
ug/l
0.52
66
983
47
241
2.01
4.64
2.6
2.8
—
—
—
0
0
188
2449
0.69
4.63
4.0
6.1
3.62
3.64
ug/l
0.01
162
2168
395
4522
0.73
4.34
5.6
4.4
1.46
1.25
mmol/l
6.80
363
4039
15
45
3.38
4.34
1.3
1.7
—
—
—
0
0
15
45
3.38
4.34
1.5
1.3
—
—
—
0
0
248
1980
1.38
3.98
6.7
4.1
41.26
10.05
mg/mmol
4.97
204
1272
19
70
2.76
3.94
3.4
2.6
—
—
—
0
0
47
258
1.88
3.85
3.2
2.8
0.74
0.88
g/l
0.14
41
221
144
1055
1.45
3.75
5.3
3.4
2.24
2.20
e6/l
0.03
81
566
99
675
1.54
3.65
6.1
4.0
—
—
—
0
0
195
1519
1.38
3.58
5.0
2.8
4.79
5.15
e6/l
0.27
184
1392
459
5068
0.75
3.45
52.8
20.2
29.87
28.11
mg/l
0.69
448
4379
15
53
2.87
3.37
1.5
1.7
10.09
8.23
mmol/l
0.53
15
53
239
1944
1.34
3.29
5.9
3.3
6.24
7.17
mmol/l
4.16
220
1603
355
3055
1.31
3.28
14.0
8.7
4.96
4.36
e9/l
4.51
321
2634
240
1955
1.34
3.27
3.1
2.1
203.15
271.25
u/l
0.74
229
1840
13
43
3.06
3.26
1.7
1.8
—
—
—
0
0
36
192
1.92
3.25
1.7
1.5
—
—
—
0
0
16
60
2.70
3.24
1.9
2.6
1798.75
930.15
mg
0.86
16
60
428
4755
0.76
3.24
11.4
7.2
44.91
40.68
mmol/mol
9.61
401
4353
11
29
3.83
3.19
1.6
1.6
—
—
—
0
0
415
4624
0.77
3.17
6.2
5.1
2.18
2.01
mu/l
1.70
386
4143
147
1114
1.40
3.15
4.5
3.3
1.28
1.22
e6/l
0.06
82
626
13
40
3.29
3.15
1.7
1.6
—
—
—
0
0
13
40
3.29
3.15
1.7
1.6
—
—
—
0
0
13
40
3.29
3.15
1.7
1.6
—
—
—
0
0
402
3532
1.30
3.13
17.0
5.1
8.11
6.90
mmol/l
12.98
390
3378
23
106
2.21
3.05
1.8
1.7
2.00
5.00
iu/l
—
9
33
13
45
2.92
3.03
1.8
1.8
—
—
—
0
0
11
31
3.58
3.00
2.7
1.7
—
—
—
0
0
11
32
3.47
2.90
1.6
1.6
—
—
—
0
0
254
2121
1.30
2.83
6.7
3.7
86.27
118.80
e6/l
0.26
219
1670
179
1425
1.34
2.80
5.3
2.6
—
—
—
0
0
221
1815
1.31
2.78
6.0
3.5
0.77
0.60
e6/l
0.41
186
1384
12
39
3.11
2.78
1.3
1.1
82.08
96.85
%
0.56
12
34
5
6
8.37
2.75
1.0
1.3
1.97
1.91
umol/24h
—
5
6
301
2586
1.28
2.65
5.6
3.0
—
—
estimate
—
0
0
32
178
1.83
2.59
8.3
4.0
6.43
1.92
index
0.47
14
96
9
25
3.63
2.58
1.9
1.5
16.78
6.42
u/l
—
9
19
42
659
0.62
2.46
6.4
5.1
32.53
32.57
%
0.01
30
419
11
38
2.92
2.42
1.6
1.5
—
—
—
0
0
28
153
1.86
2.41
1.7
1.3
—
—
—
0
0
13
53
2.48
2.28
1.3
1.1
—
—
—
0
0
7
18
3.91
2.25
1.4
1.2
—
—
—
0
0
168
1368
1.29
2.21
2.0
1.8
1244.41
1181.16
nmol/l
0.31
143
1039
8
24
3.36
2.18
1.5
1.6
—
—
—
0
0
8
24
3.36
2.18
1.5
1.6
—
—
—
0
0
8
24
3.36
2.18
1.5
1.6
—
—
—
0
0
8
24
3.36
2.18
1.5
1.6
—
—
—
0
0
8
24
3.36
2.18
1.4
1.2
9.25
40.32
u/l
—
8
19
14
61
2.32
2.15
1.3
1.1
1.74
1.61
g/l
0.42
14
55
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
14
4.31
2.15
3.3
3.4
172.50
128.14
%
—
6
14
18
88
2.07
2.12
4.8
2.3
30.17
32.66
pg
1.16
18
88
5
10
5.02
2.07
1.0
1.1
0.78
0.64
umol/24h
—
5
5
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
10
5.02
2.07
1.6
1.7
109.20
96.90
%
—
5
10
158
1907
0.78
2.03
2.5
2.0
1.57
1.29
mmol/l
2.91
145
1566
20
104
1.95
2.01
1.3
1.2
—
—
—
0
0
8
26
3.10
2.01
1.4
1.5
—
—
—
0
0
13
57
2.30
1.98
1.3
1.2
2.29
3.58
u/ml
—
7
19
6
16
3.77
1.93
1.0
1.0
1438.50
1670.38
miu/ml
—
6
16
16
78
2.07
1.92
1.6
1.6
—
—
—
0
0
34
213
1.62
1.88
1.2
1.2
77.03
146.26
u/ml
1.04
14
74
9
34
2.67
1.87
1.1
1.0
—
—
—
0
0
37
241
1.56
1.76
3.7
1.8
—
—
—
0
0
61
443
1.41
1.72
5.8
3.1
40.34
57.82
ml/min/173m2
3.22
35
207
13
61
2.15
1.72
1.4
1.1
2.43
6.96
u/ml
—
7
27
5
13
3.86
1.71
1.4
1.0
—
—
—
0
0
5
13
3.86
1.71
1.4
1.0
—
—
—
0
0
10
213
0.46
1.68
1.2
1.0
—
—
—
0
0
7
25
2.82
1.65
3.6
3.0
5.11
4.86
kpa
—
7
25
7
25
2.82
1.65
3.6
3.0
8.71
10.79
kpa
—
7
25
10
41
2.46
1.64
2.5
2.6
—
—
—
0
0
5
14
3.59
1.61
1.2
1.1
—
—
—
0
0
14
70
2.02
1.59
2.3
1.4
—
—
—
0
0
14
70
2.02
1.59
2.4
1.4
—
—
—
0
0
10
43
2.34
1.59
1.8
1.7
—
—
—
0
0
349
3805
0.84
1.54
5.2
4.0
15.15
15.10
pmol/l
0.11
332
3363
49
670
0.71
1.51
15.8
9.1
—
—
—
0
0
7
28
2.51
1.45
1.6
1.0
—
—
—
0
0
7
28
2.51
1.45
1.6
1.0
—
—
—
0
0
14
73
1.93
1.44
2.4
2.0
88.41
89.23
%
0.22
14
73
35
237
1.50
1.44
12.1
4.0
24.70
24.89
mmol/l
0.12
35
217
6
22
2.74
1.43
1.2
1.0
—
—
—
0
0
10
46
2.19
1.40
1.1
1.2
—
—
—
0
0
38
265
1.46
1.37
3.7
1.8
—
—
—
0
0
0
37
0.00
1.34
0.0
3.4
—
0.62
—
0
37
13
68
1.93
1.34
2.5
1.4
—
—
—
0
0
5
18
2.79
1.28
1.0
1.3
—
—
—
0
0
6
25
2.41
1.24
1.2
2.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
25
2.41
1.24
1.3
1.1
—
—
—
0
0
0
33
0.00
1.16
0.0
1.5
—
1.18
—
0
21
0
33
0.00
1.16
0.0
1.5
—
1.21
—
0
21
0
33
0.00
1.16
0.0
1.5
—
0.93
—
0
21
8
39
2.06
1.15
2.1
1.4
—
—
—
0
0
8
39
2.06
1.15
2.1
1.4
—
—
—
0
0
8
40
2.01
1.12
5.3
2.2
292.13
113.39
ng/l
—
8
40
7
31
2.27
1.10
1.9
1.2
—
—
—
0
0
7
31
2.27
1.10
1.9
1.2
—
—
—
0
0
149
1704
0.84
1.10
6.6
4.6
0.00
0.01
estimate
0.78
50
561
10
52
1.93
1.06
2.6
1.8
1.04
12256.92
u/l
—
5
12
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
23
155
1.50
1.02
2.4
2.4
336.76
103.08
ug/min
0.49
15
93
12
68
1.78
1.00
2.5
1.4
—
—
—
0
0
12
68
1.78
1.00
2.5
1.4
—
—
—
0
0
18
115
1.58
1.00
1.3
1.2
43.98
43.65
u/l
0.00
13
97
20
132
1.53
0.97
1.6
1.5
—
—
—
0
0
12
69
1.75
0.96
2.5
1.4
—
—
—
0
0
10
55
1.83
0.92
18.6
3.7
401.50
327.69
umol/l
—
10
49
14
216
0.64
0.87
1.1
1.9
—
—
—
0
0
6
30
2.01
0.87
4.2
4.9
—
—
—
0
0
8
44
1.83
0.86
1.0
1.1
—
—
—
0
0
21
145
1.46
0.85
1.5
1.5
—
—
—
0
0
380
4009
0.89
0.83
63.0
24.7
15.01
13.99
%
23.11
375
3956
216
1974
1.13
0.81
2.1
1.8
19.26
19.79
nmol/l
0.18
192
1663
270
2503
1.12
0.80
3.4
2.5
—
—
—
0
0
276
2562
1.12
0.80
8.8
4.5
143.24
106.25
ng/l
0.39
233
2051
232
2132
1.13
0.79
5.8
3.3
2.32
2.35
mmol/l
1.62
215
1904
8
48
1.67
0.79
2.8
2.4
578.00
556.52
ml
—
8
29
25
183
1.38
0.76
1.6
1.6
0.36
0.37
mg/l
0.06
14
76
62
515
1.22
0.76
14.7
4.0
1.20
1.22
mmol/l
1.68
57
441
11
67
1.65
0.75
3.3
4.0
—
—
—
0
0
7
38
1.85
0.73
1.3
1.1
—
—
—
0
0
155
1396
1.14
0.73
2.0
1.9
426.89
18888347.84
pmol/l
0.94
140
1133
7
39
1.80
0.72
1.9
1.3
70.86
89.05
pmol/l
—
7
39
402
3835
1.10
0.67
7.4
5.5
6923.75
1784.65
e6/l
—
8
84
7
43
1.63
0.67
1.3
1.1
—
—
—
0
0
14
200
0.69
0.64
1.0
1.8
—
—
—
0
0
43
521
0.81
0.63
1.4
1.4
—
—
—
0
0
17
121
1.41
0.62
1.2
1.2
—
23.85
—
0
6
5
30
1.67
0.61
1.2
1.1
0.03
0.12
u/ml
—
5
19
68
584
1.18
0.61
6.0
2.7
0.36
0.66
e6/l
0.91
68
565
380
3966
0.91
0.60
61.7
26.6
326.71
330.94
g/l
11.49
375
3927
21
159
1.33
0.55
1.6
1.6
20.90
14.35
u/ml
—
5
24
207
2210
0.91
0.53
6.4
4.7
0.02
0.05
estimate
0.63
54
527
10
66
1.52
0.52
1.2
1.4
—
—
—
0
0
6
40
1.50
0.51
1.3
1.3
—
—
—
0
0
254
2409
1.08
0.45
4.0
2.4
72.75
79.06
nmol/l
2.86
229
2100
5
31
1.62
0.43
1.6
1.3
—
—
—
0
0
128
1382
0.91
0.42
4.5
3.2
2.49
2.47
mmol/l
0.86
112
1221
8
59
1.36
0.41
1.0
1.3
—
—
—
0
0
21
168
1.26
0.40
1.5
1.4
224.77
273.47
ug/g
0.47
13
93
5
80
0.62
0.35
1.6
1.7
642.40
283.77
mu/l
—
5
75
289
2783
1.06
0.33
2.8
2.4
93.48
93.22
pmol/l
0.03
171
1497
93
1005
0.91
0.33
1.4
1.2
0.76
1.50
u/ml
1.55
21
260
382
3925
0.94
0.32
6.0
4.3
23.32
14.93
mm/h
11.90
358
3602
302
3121
0.94
0.31
5.3
3.3
75.40
57.57
u/l
2.20
284
2890
19
156
1.22
0.31
1.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.4
1.4
—
—
—
0
0
19
158
1.21
0.28
1.1
1.2
—
—
—
0
0
8
67
1.20
0.26
2.0
1.3
—
—
—
0
0
6
82
0.73
0.24
2.8
1.2
0.85
0.88
g/l
—
6
82
283
2908
0.96
0.23
6.0
4.5
0.00
0.00
estimate
-0.00
66
636
7
93
0.75
0.22
1.1
1.7
236.29
217.30
pmol/l
—
7
86
47
430
1.10
0.22
1.9
1.6
1.67
1.57
%
0.70
38
358
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
138
1322
1.05
0.20
5.7
4.9
10.91
1.02
kg/l
0.50
102
904
12
99
1.21
0.19
1.2
1.4
—
—
—
0
0
19
166
1.15
0.18
1.2
1.4
—
—
—
0
0
12
101
1.19
0.16
1.0
1.1
—
3.94
—
0
7
9
81
1.11
0.15
1.1
2.0
—
—
—
0
0
13
148
0.88
0.12
5.2
4.2
20.46
30.67
mg/l
0.99
13
111
427
4218
1.03
0.12
16.2
8.2
98.63
83.02
u/l
1.69
413
3967
73
758
0.96
0.10
1.3
1.3
135.19
35.14
iu/ml
0.90
30
245
292
2960
0.98
0.10
5.9
4.6
0.05
0.49
estimate
0.44
61
621
5
44
1.14
0.10
1.2
1.1
—
—
—
0
0
38
401
0.94
0.09
1.4
1.4
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
—
—
0
0
22
204
1.08
0.08
1.1
1.3
—
—
—
0
0
158
1548
1.03
0.08
6.1
4.1
0.00
0.07
estimate
0.71
46
491
8
76
1.05
0.07
2.0
1.3
18.01
26.94
iu/l
—
8
62
7
82
0.85
0.07
1.7
1.2
—
—
—
0
0
69
705
0.98
0.04
1.3
1.3
11.53
8.88
u/ml
0.16
32
246
38
391
0.97
0.03
1.5
1.4
—
—
—
0
0
68
690
0.98
0.02
3.8
4.3
4.20
29.96
ug/l
1.49
58
588
294
2938
1.00
0.00
5.8
4.6
41.64
5.29
estimate
0.65
69
662
13
131
0.99
0.00
1.1
1.3
—
—
—
0
0
10
96
1.04
0.00
1.1
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
12.30
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.1
—
2.25
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_PULMOEDEMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PULMOEDEMA | 3.634 [3.06, 4.32] | < 0.001 |
| Birth year | 0.996 [0.99, 1.01] | 0.435 |
During the follow-up period (1.1.1998 — 31.12.2019), 1992 out of 2704 females with J10_PULMOEDEMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PULMOEDEMA | 4.391 [3.53, 5.47] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 1713 out of 2356 males with J10_PULMOEDEMA died.
Mortality risk
Mortality risk for people of age
years, who have J10_PULMOEDEMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.404% | 0.926% |
| 5 | 2.256% | 4.818% |
| 10 | 5.214% | 12.463% |
| 15 | 10.119% | 22.504% |
| 20 | 17.492% | 35.623% |
Relationships between endpoints
↥Index endpoint: J10_PULMOEDEMA – Pulmonary oedema
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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