Other vitreous opacities

H7_VITROPACIT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H43.3
  • Cause of death: ICD-10 H43.3

2 out of 7 registries used, show all original rules.

1819

4. Check minimum number of events

None

1819

5. Include endpoints

None

1819

6. Filter based on genotype QC (FinnGen only)

1646

Control definitions (FinnGen only)

Control exclude
H7_VITREOUS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H43
Name in latin
Opacitates corporis vitrei

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9084 5174 3874
Only index persons 8664 4997 3667
Unadjusted period prevalence (%)
Whole population 0.13 0.15 0.11
Only index persons 0.17 0.18 0.14
Median age at first event (years)
Whole population 62.97 61.94 64.41
Only index persons 62.64 61.65 64.00

-FinnGen-

Key figures

All Female Male
Number of individuals 1646 978 668
Unadjusted period prevalence (%) 0.33 0.35 0.31
Median age at first event (years) 62.76 59.83 67.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1706
Matched controls
17060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H43.3
ICD-10 Finland
Other vitreous opacities
4503599627370496.0
307.7
1705
21
H43.8
ICD-10 Finland
Other disorders of vitreous body
40.0
307.7
429
142
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
13.6
147.7
142
113
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.5
96.0
410
1415
H43.1
ICD-10 Finland
Vitreous haemorrhage
163.8
89.0
93
6
H53.1
ICD-10 Finland
Subjective visual disturbances
4.6
88.2
231
562
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.7
85.1
310
959
H33.3
ICD-10 Finland
Retinal breaks without detachment
6.9
79.1
127
197
CKC12
NOMESCO Finland
Photocoagulation of retina
6.4
77.5
133
221
H26.4
ICD-10 Finland
After-cataract
3.4
67.6
286
966
H43.9
ICD-10 Finland
Disorder of vitreous body, unspecified
30.1
66.3
44
15
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.4
65.4
271
903
H53.9
ICD-10 Finland
Visual disturbance, unspecified
5.5
65.1
132
257
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.6
64.8
239
739
H33.0
ICD-10 Finland
Retinal detachment with retinal break
6.2
63.8
112
190
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
60.2
427
1909
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
51.8
671
3874
WX140
NOMESCO Finland
Parabulbar anesthesy
4.2
50.0
141
359
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
47.6
678
4030
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
+∞
46.0
44
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
44.5
285
1196
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
7.3
37.0
55
78
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.1
35.3
160
555
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
33.5
810
5588
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.7
32.5
105
294
H25.1
ICD-10 Finland
Senile nuclear cataract
1.9
32.4
536
3267
H52.1
ICD-10 Finland
Myopia
4.0
31.0
91
238
CKD40
NOMESCO Finland
Endophotocoagulation of retina
7.1
29.8
45
65
H25.0
ICD-10 Finland
Senile incipient cataract
2.8
28.7
157
603
XCK00
NOMESCO Finland
Perimetry
2.9
27.2
132
475
R42
ICD-10 Finland
Dizziness and giddiness
1.9
25.9
435
2634
H20.1
ICD-10 Finland
Chronic iridocyclitis
7.6
24.7
35
47
F29
ICPC
Eye symptom/complaint other
2.2
21.4
208
1033
F05
ICPC
Visual disturbance other
3.5
21.4
76
227
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
7.6
21.3
30
40
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.2
20.4
84
275
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
20.2
621
4405
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
5.5
19.8
38
70
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
19.7
508
3438
F04
ICPC
Visual floaters/spots
17.9
19.6
30
17
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
19.2
164
772
XCH00
NOMESCO Finland
Eye pressure measurement
2.8
19.1
101
380
R51.80
ICD-10 Finland
Headache
1.9
19.1
278
1593
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.4
18.9
68
205
L03
ICPC
Low back symptom/complaint
1.6
18.5
515
3545
H26.2
ICD-10 Finland
Complicated cataract
5.3
18.5
37
71
R20.2
ICD-10 Finland
Paraesthesia of skin
2.4
18.5
138
614
N03AX12
ATC
[U] gabapentin; oral
1.8
18.1
294
1742
F13
ICPC
Eye sensation abnormal
3.3
18.0
68
211
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
4.2
17.6
47
115
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
17.6
401
2617
H33.5
ICD-10 Finland
Other retinal detachments
15.0
17.1
28
19
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
16.9
171
861
H25.8
ICD-10 Finland
Other senile cataract
2.0
16.8
204
1098
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
4.4
16.7
41
94
J02AC01
ATC
fluconazole; systemic
1.6
16.6
646
4791
H35.4
ICD-10 Finland
Peripheral retinal degeneration
7.3
15.7
23
32
S01FA04
ATC
cyclopentolate; ophthalmic
5.3
15.2
30
57
M54.5
ICD-10 Finland
Low back pain
1.5
15.1
619
4617
H43
ICD-10 Finland
Disorders of vitreous body
14.1
15.0
25
18
H53.8
ICD-10 Finland
Other visual disturbances
4.5
15.0
36
81
SPAT1097
SPAT
Recording of ECG
1.8
15.0
252
1503
M79.6
ICD-10 Finland
Pain in limb
1.5
14.9
744
5784
SPAT1263
SPAT
Sampling
1.5
14.9
679
5179
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
14.7
253
1518
H57.1
ICD-10 Finland
Ocular pain
2.7
14.6
79
301
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
4.0
14.4
40
101
A02BC02
ATC
pantoprazole; systemic
1.5
14.3
1161
9936
AA1AD
NOMESCO Finland
CT of head and brain
1.5
13.6
504
3664
S01BC05
ATC
ketorolac; ophthalmic
2.7
13.5
75
290
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.5
13.3
32
72
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.9
13.3
38
98
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.4
13.3
88
371
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
13.2
310
2023
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
13.1
313
2052
UJF32
NOMESCO Finland
Coloscopy
1.5
13.0
441
3137
H53
ICD-10 Finland
Visual disturbances
5.6
12.9
24
43
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.6
12.8
73
286
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
12.7
370
2540
A04
ICPC
Weakness/tiredness general
1.7
12.7
271
1722
L17
ICPC
Foot/toe symptom/complaint
1.5
12.6
514
3803
S01ED01
ATC
timolol; ophthalmic
2.7
12.5
65
243
G44.2
ICD-10 Finland
Tension-type headache
1.7
12.5
227
1382
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.1
12.4
51
167
D06
ICPC
Abdominal pain localized other
1.9
12.4
154
832
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
2.2
12.3
110
527
R02
ICPC
Shortness of breath/dyspnoea
1.7
12.3
241
1497
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
12.3
492
3622
H53.4
ICD-10 Finland
Visual field defects
3.3
12.1
46
144
G04CB01
ATC
finasteride; oral
1.8
12.1
179
1025
SPAT1260
SPAT
Consultation of another employee
1.6
12.0
286
1868
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
11.9
147
794
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
11.5
142
766
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
11.5
614
4770
N02BF01
ATC
gabapentin; oral
1.8
11.4
186
1095
L01
ICPC
Neck symptom/complaint
1.6
11.4
272
1776
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
11.4
302
2024
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
11.4
179
1043
EB1VA, ,
NOMESCO Finland
1.6
11.4
290
1925
M03BX02
ATC
tizanidine; oral
1.4
11.3
994
8438
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
11.3
183
1076
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
11.2
171
989
R21
ICPC
Throat symptom/complaint
1.6
11.1
304
2052
N02BE01
ATC
paracetamol; systemic, rectal
1.7
11.1
1503
13887
S01BC03
ATC
diclofenac; ophthalmic
3.2
11.0
44
142
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
11.0
424
3084
G04CA01
ATC
alfuzosin; oral
1.7
11.0
201
1224
G47.3
ICD-10 Finland
Sleep apnoea
1.5
11.0
375
2660
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
10.9
227
1430
N02AX02
ATC
tramadol; systemic, rectal
1.4
10.8
697
5584
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.7
10.8
216
1347
WX142
NOMESCO Finland
Sub-tenon anesthesy
5.6
10.7
20
36
J01FA10
ATC
azithromycin; systemic
1.4
10.6
888
7438
H3600, E113,
ICD-10 Finland
4.4
10.5
26
60
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.7
10.5
187
1130
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
10.5
430
3164
R03AC02
ATC
salbutamol; inhalant
1.4
10.4
877
7344
A02BC05
ATC
esomeprazole; systemic
1.4
10.4
649
5162
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
10.4
1139
9979
DAX08
NOMESCO Finland
Fitting of hearing aid
2.0
10.4
107
542
SPAT1301
SPAT
No procedures
1.5
10.3
492
3726
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
10.3
652
5197
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
10.1
743
6067
A02BC03
ATC
lansoprazole; oral
1.5
10.0
460
3456
SFA10
NOMESCO Finland
One-surface restoration
1.4
10.0
863
7237
XJH00
NOMESCO Finland
Transanal ultrasonography
2.1
10.0
96
474
SPAT1310
SPAT
Counselling related to known health issue
1.4
9.9
494
3769
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.8
9.8
150
866
S01EC01
ATC
acetazolamide; systemic
3.1
9.8
39
126
L12
ICPC
Hand/finger symptom/complaint
1.6
9.8
279
1899
S18
ICPC
Laceration/cut
1.4
9.7
780
6453
R05
ICPC
Cough
1.5
9.7
401
2950
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
5.3
9.6
19
36
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.0
9.6
107
558
ZXA10
NOMESCO Finland
Bilateral
1.5
9.5
288
1985
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
9.5
469
3567
R74
ICPC
Upper respiratory infection acute
1.4
9.4
476
3634
N03AX16
ATC
[U] pregabalin
1.5
9.4
365
2652
H26.9
ICD-10 Finland
Cataract, unspecified
3.3
9.3
35
109
D07AC01
ATC
betamethasone; topical
1.4
9.3
575
4543
R52.9
ICD-10 Finland
Pain, unspecified
1.7
9.1
168
1024
H93.1
ICD-10 Finland
Tinnitus
1.9
9.1
118
648
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
9.0
447
3396
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
9.0
205
1322
XCD20
NOMESCO Finland
Photoangiography of eye
3.5
8.9
30
87
J01CA04
ATC
amoxicillin; systemic
1.4
8.9
1317
11968
A02BA02
ATC
ranitidine; systemic
1.5
8.9
304
2148
R12
ICD-10 Finland
Heartburn
1.8
8.7
137
799
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
8.6
68
311
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
8.5
99
525
H33
ICD-10 Finland
Retinal detachments and breaks
20.1
8.5
12
6
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
8.4
53
219
A07AA02
ATC
nystatin; oral
2.0
8.4
95
498
H40.0
ICD-10 Finland
Glaucoma suspect
1.8
8.4
130
754
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
8.3
584
4697
J01DB01
ATC
cefalexin; oral
1.4
8.3
1337
12233
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
8.3
302
2161
H34.8
ICD-10 Finland
Other retinal vascular occlusions
2.8
8.3
40
145
D01
ICPC
Abdominal pain/cramps general
1.6
8.2
193
1252
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.8
8.2
119
677
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
8.2
284
2010
M25.5
ICD-10 Finland
Pain in joint
1.4
8.2
521
4121
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
8.1
448
3458
H30.2
ICD-10 Finland
Posterior cyclitis
11.8
8.1
14
12
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.8
8.0
111
622
A98
ICPC
Health maint/preventive medicine
1.9
8.0
1622
15514
K07.60
ICD-10 Finland
Snapping jaw
2.0
8.0
83
422
R35
ICD-10 Finland
Polyuria
1.8
8.0
112
631
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
8.0
303
2184
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.9
557
4469
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
7.9
92
487
N06AA09
ATC
amitriptyline; systemic
1.7
7.9
151
929
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
7.9
771
6501
R00.2
ICD-10 Finland
Palpitations
1.8
7.9
125
730
CKC60
NOMESCO Finland
Local buckling of sclera using implant
6.6
7.9
19
29
L08
ICPC
Shoulder symptom/complaint
1.4
7.9
366
2740
SPAT1153
SPAT
Removal of sutures
1.4
7.9
493
3884
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
7.9
1020
8967
N01
ICPC
Headache
1.7
7.8
159
996
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.8
200
1327
R01AD09
ATC
mometasone; nasal
1.3
7.7
684
5680
L87
ICPC
Bursitis/tendinitis/synovitis NOS
3.1
7.7
31
101
H02
ICPC
Hearing complaint
1.5
7.7
244
1694
A02BC01
ATC
omeprazole; systemic
1.4
7.7
417
3205
N41.1
ICD-10 Finland
Chronic prostatitis
2.7
7.7
40
151
Z01.2
ICD-10 Finland
Dental examination
1.3
7.7
705
5887
R01AD58
ATC
fluticasone, combinations; nasal
1.4
7.7
360
2699
H02AB06
ATC
prednisolone; systemic
1.3
7.6
740
6226
R05
ICD-10 Finland
Cough
1.4
7.6
329
2430
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
7.6
379
2873
J01AA02
ATC
doxycycline; systemic
1.4
7.5
1252
11390
L13
ICPC
Hip symptom/complaint
1.4
7.5
314
2305
N17
ICPC
Vertigo/dizziness
1.5
7.4
207
1399
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.9
7.4
34
120
N06AX11
ATC
mirtazapine; oral
1.4
7.4
528
4240
S21
ICPC
Skin texture symptom/complaint
1.5
7.3
240
1677
CS494
NOMESCO Finland
Other visual field testing
2.4
7.3
47
197
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
7.3
124
740
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
7.3
446
3494
P01
ICPC
Feeling anxious/nervous/tense
1.6
7.3
164
1054
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
2.1
7.2
68
334
F01
ICPC
Eye pain
2.3
7.2
51
223
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.2
385
2950
M01AH01
ATC
celecoxib; oral
1.5
7.2
272
1958
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.1
627
5188
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
7.1
175
1149
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
7.1
346
2608
R07.3
ICD-10 Finland
Other chest pain
1.6
7.1
166
1077
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
7.1
315
2336
R01AD12
ATC
fluticasone furoate; nasal
1.4
7.1
457
3609
L10
ICPC
Elbow symptom/complaint
1.9
7.1
82
435
M48.0
ICD-10 Finland
Spinal stenosis
1.5
7.1
201
1364
K30
ICD-10 Finland
Functional dyspepsia
1.6
7.0
174
1143
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
7.0
214
1473
S82
ICPC
Naevus/mole
1.5
7.0
219
1515
A01
ICPC
Pain general/multiple sites
1.6
7.0
161
1040
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
7.0
136
842
R06.0
ICD-10 Finland
Dyspnoea
1.4
7.0
427
3341
ZXA00
NOMESCO Finland
Right side
1.4
6.9
397
3073
SPAT1240
SPAT
Therapeutic discussion
1.6
6.9
148
940
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
6.9
193
1305
G47.8
ICD-10 Finland
Other sleep disorders
3.1
6.9
27
87
S01BA01
ATC
dexamethasone; ophthalmic
2.2
6.9
55
254
R06AE07
ATC
cetirizine; oral
1.3
6.9
656
5484
S01BA07
ATC
fluorometholone; ophthalmic
3.2
6.9
26
82
K03.80
ICD-10 Finland
Irradiated enamel
1.9
6.8
89
491
WX720
NOMESCO Finland
Own respiration
1.9
6.8
84
455
M54.2
ICD-10 Finland
Cervicalgia
1.7
6.8
131
809
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
6.8
345
2617
D02
ICPC
Abdominal pain epigastric
1.8
6.8
98
558
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
6.8
133
826
SXC05
NOMESCO Finland
Other oral or dental procedure
1.8
6.7
95
537
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.1
6.7
58
276
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
6.7
94
530
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
1.9
6.7
79
422
H53.2
ICD-10 Finland
Diplopia
2.2
6.7
55
257
N04BC05
ATC
pramipexole; oral
1.7
6.7
120
728
N06AX21
ATC
duloxetine; oral
1.5
6.7
183
1232
N76.0
ICD-10 Finland
Acute vaginitis
1.8
6.6
88
488
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.4
6.6
446
3539
S01ED51
ATC
timolol, combinations; ophthalmic
1.7
6.6
117
707
H01
ICPC
Ear pain/earache
1.6
6.6
169
1120
H50.52
ICD-10 Finland
Exophoria
3.5
6.6
22
64
WZC00, ,
SPAT
1.5
6.6
226
1595
SPAT1216
SPAT
Assessment of functional ability
1.5
6.6
238
1697
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.6
6.6
161
1056
R07.0
ICD-10 Finland
Pain in throat
1.8
6.6
100
579
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
6.5
246
1768
C10AX09
ATC
ezetimibe; oral
1.4
6.5
265
1933
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
6.5
321
2423
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
6.2
6.5
16
26
WZA90
NOMESCO Finland
Other medical or dental certificate
1.4
6.5
341
2602
B07.9
ICD-10 Finland
Verruca simplex
2.2
6.4
54
255
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.4
591
4906
C07AA05
ATC
propranolol; systemic
1.4
6.4
292
2174
SPAT1312
SPAT
General health counselling
1.3
6.3
459
3678
M01AB05
ATC
diclofenac; systemic, rectal
1.3
6.3
1023
9140
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.3
244
1762
XQ848
NOMESCO Finland
Dermatological photography
2.2
6.3
51
237
H33.2
ICD-10 Finland
Serous retinal detachment
9.3
6.3
12
13
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
6.3
244
1763
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.3
790
6830
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.2
879
7706
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
6.2
584
4853
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
26.8
6.2
8
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
26.8
6.2
8
*
H3603, E103,
ICD-10 Finland
7.0
6.2
14
20
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.2
833
7255
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.2
336
2575
P03
ICPC
Feeling depressed
1.6
6.1
134
855
SPAT1360
SPAT
Extensive global examination
1.7
6.1
102
606
R06AX27
ATC
desloratadine; oral
1.3
6.1
406
3209
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.6
6.1
159
1057
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.1
220
1566
R19.4
ICD-10 Finland
Change in bowel habit
2.2
6.1
51
240
N06AB04
ATC
citalopram; systemic
1.4
6.1
301
2269
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.2
6.1
47
214
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.6
6.1
142
921
A11
ICPC
Chest pain NOS
1.6
6.1
135
865
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
12.6
6.1
10
8
M79.7
ICD-10 Finland
Fibromyalgia
2.1
6.1
54
261
XF402
NOMESCO Finland
ECG with work load test
1.6
6.0
158
1053

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
687
4970
1.64
20.80
3.1
2.6
57.17
75.72
u/l
0.60
636
4597
493
3418
1.62
16.95
1.4
1.3
2.62
1.62
u/ml
0.33
139
918
1301
11268
1.65
16.81
5.5
4.4
12.37
12.66
mm/h
0.28
1223
10518
1348
11814
1.67
16.26
9.1
8.4
75.72
79.46
u/l
2.67
1282
11228
993
8122
1.53
16.07
4.9
3.9
0.00
5.52
estimate
1.83
227
1744
975
8019
1.50
14.81
4.8
3.9
0.00
0.00
estimate
0.50
226
1702
991
8178
1.51
14.81
4.9
3.9
0.02
0.19
estimate
0.47
216
1631
774
6086
1.50
14.56
4.7
3.9
0.03
0.05
estimate
0.40
185
1396
970
7994
1.49
14.41
7.6
7.3
1.21
1.21
mmol/l
0.49
841
6931
645
4903
1.51
14.20
2.6
2.2
143.33
221.00
u/l
3.09
604
4646
760
5986
1.49
14.00
4.6
3.8
45.72
68.48
ng/l
0.55
535
4309
310
1998
1.67
13.89
3.1
3.4
4.06
4.85
e9/l
1.45
252
1736
1603
14975
2.17
13.36
23.3
19.9
3.99
3.97
mmol/l
1.41
1578
14667
1509
13847
1.78
12.89
7.4
6.5
39.52
39.39
mmol/mol
0.22
1408
12946
1312
11633
1.55
12.84
5.1
4.5
15.02
14.84
pmol/l
2.01
1209
10670
1599
14951
2.11
12.84
23.2
19.7
139.85
139.68
mmol/l
2.01
1575
14676
292
1890
1.66
12.79
2.6
2.4
116.13
130.83
ug/g
0.46
237
1512
891
7341
1.45
12.46
16.8
15.2
1.26
1.25
inr
0.20
759
6129
1563
14570
1.87
11.62
20.1
16.6
22.60
24.58
mg/l
1.70
1303
12097
857
7068
1.43
11.57
5.6
5.2
35.69
35.51
g/l
0.44
790
6647
1490
13706
1.69
11.56
6.3
5.5
1.88
1.94
mu/l
0.83
1390
12652
869
7189
1.43
11.51
6.6
6.5
1.21
1.21
mmol/l
0.43
800
6654
584
4509
1.45
11.23
5.1
4.0
0.00
0.01
estimate
1.54
205
1594
980
8342
1.41
10.70
6.5
6.7
10.45
11.46
umol/l
3.48
931
7977
1150
10093
1.43
10.39
6.2
4.7
125.20
1170.10
e6/l
—
10
154
932
7892
1.40
10.32
6.4
6.1
0.04
0.04
e9/l
0.81
831
6772
1058
9159
1.41
10.27
5.3
5.1
6.63
6.70
mmol/l
0.59
1011
8709
785
6464
1.40
10.23
4.2
3.5
6.28
6.23
ph
0.55
450
3625
927
7877
1.39
9.86
6.4
6.1
0.57
0.58
e9/l
0.63
828
6759
1624
15454
2.06
9.52
25.7
21.8
79.50
77.58
umol/l
1.13
1609
15281
940
8040
1.38
9.41
6.6
6.1
2.00
1.89
e9/l
0.24
847
7063
191
1197
1.67
9.36
1.3
1.2
—
—
—
0
0
1516
14155
1.64
9.30
5.9
5.3
5.90
5.95
mmol/l
1.04
1410
12954
946
8137
1.36
8.94
6.5
6.3
0.19
0.19
e9/l
0.27
848
7087
1645
15773
2.20
8.71
30.2
25.3
6.63
6.74
e9/l
0.67
1612
15408
851
7218
1.36
8.70
3.5
3.1
112.01
127.63
ug/l
1.99
783
6712
1536
14434
1.64
8.62
5.9
5.2
4.59
4.62
mmol/l
0.49
1440
13465
1644
15767
2.17
8.58
30.2
25.3
245.82
250.28
e9/l
2.23
1619
15457
1644
15769
2.17
8.54
30.0
25.2
91.37
91.35
fl
0.06
1627
15602
1015
8863
1.36
8.50
8.7
9.6
4.22
4.11
e9/l
0.71
915
7705
1644
15772
2.17
8.49
30.1
25.3
4.43
4.45
e12/l
1.17
1614
15408
1644
15772
2.17
8.49
30.0
25.2
30.39
30.37
pg
0.18
1627
15604
1644
15772
2.17
8.49
30.5
25.8
40.02
40.10
%
0.26
1626
15594
364
2692
1.45
8.42
1.8
1.8
1154.86
1178.05
nmol/l
0.20
275
2053
1644
15776
2.16
8.42
30.3
25.5
133.72
134.17
g/l
0.64
1627
15607
831
7050
1.35
8.35
2.7
2.4
80.72
78.13
nmol/l
1.92
760
6362
1553
14654
1.67
8.32
6.7
5.9
2.64
2.69
mmol/l
1.22
1452
13609
1608
15323
1.86
8.28
14.3
12.4
24.49
25.49
u/l
2.17
1562
14907
605
4899
1.36
8.20
3.8
3.2
—
—
—
0
0
595
4815
1.36
8.07
4.7
4.2
7.40
7.40
ph
0.90
452
3487
1525
14351
1.59
7.96
5.8
5.1
1.49
1.47
mmol/l
1.11
1422
13295
461
3589
1.39
7.92
5.3
4.1
1.02
1.44
kg/l
0.50
311
2389
75
370
2.07
7.88
1.1
1.1
9.93
9.38
eliau/ml
—
7
37
93
496
1.93
7.85
1.0
1.1
—
—
—
0
0
218
1474
1.55
7.78
2.5
2.1
0.00
0.02
estimate
0.78
56
294
394
3009
1.40
7.53
1.6
1.5
2.35
2.50
g/l
0.88
256
1846
1466
13718
1.49
7.42
4.9
4.4
1.28
1.28
mmol/l
0.20
1361
12570
597
4887
1.34
7.34
3.2
3.2
1325.83
1293.46
ng/l
0.07
498
4225
429
3336
1.38
7.34
1.8
1.7
453.94
28438159.00
pmol/l
2.82
356
2778
65
319
2.08
6.95
5.3
8.5
11.05
11.31
mmol/l
0.24
60
286
65
320
2.07
6.90
5.3
8.5
104.75
105.51
mmol/l
0.65
60
287
1105
9927
1.32
6.80
3.8
3.4
46.59
49.84
u/l
0.53
1036
9324
567
4655
1.33
6.70
1.8
1.7
21.11
20.48
nmol/l
0.40
487
3913
844
7324
1.30
6.63
3.0
2.8
—
—
estimate
—
0
0
531
4326
1.33
6.60
3.9
3.4
0.01
0.03
estimate
0.79
183
1349
84
463
1.86
6.46
5.1
7.0
1.30
1.33
mmol/l
0.09
76
405
518
4217
1.33
6.44
2.5
2.3
2.80
2.84
mg/l
0.12
444
3624
835
7267
1.29
6.29
6.7
6.4
0.69
0.68
%
0.25
786
6817
154
1012
1.57
6.23
1.3
1.2
—
—
—
0
0
121
752
1.66
6.15
2.3
2.1
0.00
1.10
estimate
0.50
47
228
832
7261
1.28
6.04
6.6
6.3
2.79
2.83
%
0.21
784
6812
330
2531
1.38
6.03
2.7
2.6
2.35
2.31
g/l
0.83
301
2341
836
7303
1.28
6.01
6.6
6.2
57.22
57.56
%
0.35
803
6985
831
7272
1.28
5.83
6.7
6.4
8.93
8.89
%
0.15
784
6826
350
2724
1.36
5.81
2.8
2.6
13.31
12.94
umol/l
0.46
320
2535
847
7432
1.28
5.80
6.6
6.3
27.72
27.41
%
0.34
807
7066
150
999
1.55
5.74
6.0
6.9
25.21
24.24
mmol/l
2.57
144
955
654
5563
1.28
5.72
3.0
3.6
2.35
2.36
mmol/l
0.96
588
5051
116
727
1.64
5.72
4.3
5.7
1.76
1.55
%
1.46
110
688
647
5507
1.28
5.60
3.4
3.4
7.06
7.40
mmol/l
1.28
548
4657
317
2448
1.36
5.51
1.8
2.1
29.43
29.61
s
0.16
302
2378
489
4043
1.29
5.25
3.2
2.8
337.79
343.00
umol/l
0.56
426
3576
802
7068
1.25
5.02
2.3
2.2
101.25
95.28
pmol/l
2.61
442
3744
237
1776
1.39
4.95
1.4
1.3
—
—
—
0
0
612
5244
1.26
4.84
3.6
3.5
66.20
46.76
mg/l
0.79
391
3332
301
2355
1.34
4.77
2.9
2.6
22.79
22.80
%
0.00
273
2195
191
1393
1.42
4.66
4.4
4.1
0.56
0.69
%
0.48
62
437
249
1901
1.36
4.63
1.6
1.4
—
—
—
0
0
414
3398
1.29
4.62
1.8
1.7
1.20
1.22
mg/l
0.03
333
2638
358
2893
1.30
4.49
1.4
1.3
17.51
33.33
iu/ml
6.48
123
901
103
669
1.57
4.44
4.4
5.9
0.89
0.86
%
0.45
98
631
620
5361
1.25
4.44
4.3
4.2
10.81
8.83
mg/mmol
0.46
385
3316
190
1400
1.40
4.38
5.0
4.5
0.14
0.11
%
0.08
50
365
174
1266
1.42
4.32
3.5
3.0
142.30
197.05
ng/l
1.32
168
1165
137
953
1.48
4.31
2.7
3.3
4.42
4.49
pmol/l
0.38
128
846
180
1329
1.40
4.11
2.5
2.4
4.97
7.34
ug/l
2.78
155
1175
705
6223
1.23
4.07
2.3
2.2
—
—
—
0
0
28
123
2.30
4.04
1.2
1.1
122.57
108.54
pmol/l
0.64
28
123
185
1379
1.38
3.99
3.0
3.0
66.55
66.38
g/l
0.13
167
1271
278
2212
1.31
3.89
1.3
1.2
—
—
—
0
0
177
1316
1.38
3.89
2.5
2.4
0.42
0.52
e6/l
0.30
172
1257
287
2294
1.30
3.88
2.4
2.0
—
—
—
0
0
521
4476
1.24
3.85
4.3
4.4
—
—
—
0
0
38
194
1.98
3.79
1.4
1.5
—
—
—
0
0
38
194
1.98
3.79
1.4
1.5
—
—
—
0
0
38
194
1.98
3.79
1.4
1.5
—
—
—
0
0
38
194
1.98
3.79
1.4
1.5
—
—
—
0
0
114
789
1.48
3.71
1.2
1.2
—
—
—
0
0
531
4594
1.23
3.63
6.3
5.8
2.60
2.83
ug/l
0.30
491
4138
77
492
1.59
3.61
1.5
1.4
289.82
275.74
ug/g
0.23
45
298
151
1110
1.40
3.56
2.4
2.3
12.49
12.77
nmol/l
0.15
139
993
151
1113
1.39
3.51
3.0
2.7
—
—
—
0
0
203
1571
1.33
3.46
6.7
8.8
123.03
121.09
g/l
0.73
197
1535
130
936
1.42
3.46
1.3
1.3
72.00
59.95
au/ml
—
8
75
66
411
1.63
3.45
3.0
2.1
6242.93
4549.28
u/l
0.12
31
176
329
2716
1.26
3.43
1.4
1.3
10.16
11.65
u/ml
0.17
139
1028
196
1516
1.33
3.36
4.1
4.2
7.37
7.36
ph
0.42
129
1095
97
665
1.49
3.34
1.2
1.2
—
—
—
0
0
230
1826
1.30
3.27
1.9
1.7
—
—
—
0
0
139
1026
1.39
3.22
2.5
2.5
16.79
21.52
au/ml
0.46
18
99
270
2194
1.27
3.20
6.2
5.6
1.03
1.04
mmol/l
0.12
245
2027
188
1462
1.32
3.11
4.6
4.2
0.80
0.94
%
0.41
56
467
87
594
1.49
3.08
2.8
2.7
—
—
—
0
0
264
2151
1.27
3.07
1.4
1.3
532.12
492.53
titre
0.15
66
482
42
240
1.77
3.03
1.1
1.1
—
—
—
0
0
42
240
1.77
3.03
1.1
1.1
—
—
—
0
0
85
583
1.48
2.95
3.2
3.9
24.72
24.98
mmol/l
0.34
75
539
236
1906
1.28
2.95
5.7
5.0
33.36
32.41
%
0.71
165
1264
179
1394
1.32
2.94
4.8
4.3
0.13
0.12
%
0.07
46
398
81
551
1.49
2.93
1.6
1.6
17.90
16.42
u/ml
0.06
16
108
264
2166
1.26
2.89
1.9
1.6
—
—
—
0
0
212
1698
1.28
2.83
6.5
8.3
96.42
95.62
%
1.73
204
1644
28
144
1.96
2.80
1.7
2.1
7.25
6.75
umol/l
0.04
19
103
88
616
1.45
2.77
1.4
1.3
26.79
29.87
iu/l
0.45
80
522
708
6416
1.18
2.76
2.0
1.9
1.34
1.34
mmol/l
0.01
606
5387
163
1265
1.32
2.76
4.5
3.9
1.22
1.22
mmol/l
0.04
147
1087
18
78
2.32
2.75
3.2
2.4
606.00
1059.85
u/ml
1.06
18
78
395
3402
1.21
2.74
5.0
4.6
—
—
—
0
0
489
4296
1.19
2.74
3.5
3.1
0.00
0.02
0.49
11
93
206
1652
1.28
2.73
1.8
1.5
—
—
—
0
0
104
757
1.40
2.66
2.2
2.0
—
—
—
0
0
66
443
1.51
2.58
1.9
1.6
303.11
311.50
mu/l
0.08
61
403
155
1209
1.31
2.54
3.0
2.9
10.14
10.76
g/l
1.08
143
1112
64
431
1.50
2.47
1.3
1.3
206.11
229.73
miu/ml
0.20
21
202
8
21
3.82
2.46
1.0
1.0
—
—
—
0
0
356
3067
1.20
2.45
4.6
3.8
197.98
421.89
ng/l
2.32
268
2399
320
2729
1.21
2.45
2.6
3.3
0.82
0.82
mmol/l
0.46
301
2591
17
76
2.25
2.44
2.5
3.0
—
—
—
0
0
13
52
2.51
2.36
1.7
1.3
—
—
—
0
0
97
715
1.38
2.33
3.4
3.3
25.54
25.21
mmol/l
0.35
92
691
229
1896
1.24
2.33
6.5
8.0
7.42
7.41
ph
1.20
150
1055
583
5258
1.17
2.32
3.5
3.2
32.18
32.16
u/l
0.00
544
4966
20
99
2.03
2.26
1.9
2.3
7.34
6.94
mmol/l
—
9
64
37
224
1.67
2.25
2.6
2.5
—
—
—
0
0
64
442
1.47
2.22
1.3
1.2
3.72
2.67
u/ml
0.25
11
39
226
1880
1.23
2.21
6.4
7.9
1.46
0.94
mmol/l
1.90
198
1524
406
3573
1.18
2.18
2.9
2.7
5.66
5.86
e6/l
0.08
380
3251
52
345
1.52
2.18
1.4
1.3
16.00
9.86
u/l
1.23
44
272
8
24
3.34
2.18
1.0
1.2
—
—
—
0
0
78
562
1.41
2.16
4.0
3.8
59.94
66.70
mg/l
0.17
72
488
89
656
1.38
2.16
1.8
1.8
7.71
8.13
iu/ml
0.05
23
146
52
346
1.52
2.16
3.0
3.8
86.44
1181.68
u/ml
0.85
47
321
64
445
1.46
2.15
1.3
1.3
4.71
9.40
u/ml
0.55
17
65
7
19
3.69
2.15
1.3
1.7
—
—
—
0
0
20
102
1.97
2.10
1.1
1.0
—
—
—
0
0
155
1243
1.27
2.10
3.8
3.8
90.38
90.17
ng/l
0.01
124
1075
14
62
2.27
2.08
1.0
1.1
0.31
0.24
u/ml
—
5
25
23
124
1.87
2.07
3.3
2.2
2.17
1.88
u/field
0.08
12
72
150
1200
1.27
2.07
2.0
1.7
—
—
—
0
0
123
959
1.30
2.07
1.3
1.3
133.45
210.88
u/ml
1.13
113
887
10
37
2.71
2.07
2.3
2.1
9.21
9.48
mg/l
—
10
30
227
1904
1.22
2.06
6.5
7.9
12.72
12.26
kpa
0.59
221
1832
227
1904
1.22
2.06
6.5
7.9
5.06
5.08
kpa
0.10
221
1832
98
741
1.34
2.04
3.2
3.8
—
—
—
0
0
6
15
4.01
2.04
1.2
1.1
—
—
—
0
0
26
147
1.78
2.03
1.4
1.4
7.07
6.77
g/l
0.18
20
109
26
147
1.78
2.03
1.4
1.4
0.34
0.38
g/l
0.40
20
108
26
147
1.78
2.03
1.4
1.4
2.55
2.90
g/l
0.74
19
109
9
32
2.82
2.00
1.8
2.1
—
—
—
0
0
77
563
1.39
1.98
4.0
3.8
37.74
62.63
mg/l
0.62
71
490
13
57
2.29
1.98
1.2
1.1
—
—
—
0
0
32
195
1.65
1.93
3.4
2.6
1.54
1.41
g/24h
0.10
18
120
6
16
3.76
1.93
8.5
14.6
4.97
5.17
mmol/l
—
6
16
100
769
1.32
1.88
1.2
1.1
—
0.92
—
0
5
31
189
1.65
1.88
1.5
1.2
—
—
—
0
0
7
22
3.19
1.88
1.1
1.0
—
—
—
0
0
7
22
3.19
1.88
1.1
1.0
—
—
—
0
0
7
22
3.19
1.88
1.1
1.0
—
—
—
0
0
8
28
2.87
1.86
1.1
1.3
74.75
64.25
ug/l
—
8
28
11
46
2.40
1.85
1.2
1.1
—
—
—
0
0
11
46
2.40
1.85
1.2
1.1
—
—
—
0
0
11
46
2.40
1.85
1.2
1.1
—
—
—
0
0
9
35
2.58
1.80
1.2
1.1
—
—
—
0
0
519
4719
1.14
1.78
6.2
6.3
—
—
—
0
0
5
130
0.38
1.62
2.4
1.4
8.54
8.90
mmol/l
—
5
123
148
1220
1.23
1.62
3.4
2.7
6.03
6.09
ph
0.34
102
847
18
98
1.85
1.62
1.0
1.1
244.56
262.59
mg/l
0.30
18
80
64
472
1.37
1.61
12.0
10.0
—
—
—
0
0
132
1076
1.25
1.60
3.3
3.8
5.12
5.17
kpa
0.37
125
1034
41
279
1.48
1.60
1.7
1.3
—
11.48
—
0
5
98
773
1.28
1.57
2.7
2.4
—
—
—
0
0
129
1052
1.24
1.57
1.2
1.2
146.04
150.46
u/ml
0.04
45
391
75
571
1.33
1.55
1.2
1.2
—
—
—
0
0
58
426
1.37
1.51
2.4
2.2
12.67
11.80
mg/l
0.24
53
390
128
1048
1.24
1.51
3.4
3.8
7.41
7.42
ph
0.08
109
891
48
342
1.42
1.49
2.4
3.0
30.53
34.12
umol/l
0.69
43
309
15
79
1.91
1.49
1.0
1.2
0.54
0.50
ratio
—
9
47
86
673
1.29
1.48
1.1
1.1
—
128.88
titre
—
0
17
16
87
1.85
1.46
4.4
7.2
18.39
222.40
ug/l
0.54
11
57
359
3227
1.14
1.45
2.8
3.1
2.45
2.45
mmol/l
0.15
334
2912
31
204
1.53
1.43
1.8
1.4
0.31
0.33
nmol/l
0.04
22
154
27
172
1.58
1.43
3.9
2.2
—
—
—
0
0
10
46
2.18
1.40
2.6
2.1
12.30
8.93
%
—
10
41
7
29
2.42
1.39
1.1
1.1
24.71
26.32
%
—
7
22
53
390
1.37
1.39
3.3
3.3
1.46
1.57
mmol/l
0.43
53
382
59
442
1.35
1.38
3.7
3.7
3.80
3.90
mmol/l
1.03
59
436
171
1456
1.19
1.38
2.6
2.6
69.88
69.93
e9/l
0.01
143
1081
188
1615
1.18
1.38
3.8
3.6
7.38
7.38
ph
0.04
120
931
28
182
1.55
1.37
3.5
2.6
—
—
—
0
0
18
104
1.74
1.37
1.0
1.1
2.80
3.24
nmol/l
—
5
16
175
1499
1.19
1.33
2.4
2.2
387.08
381.42
nmol/l
0.12
159
1387
29
192
1.52
1.32
1.2
1.4
8461.19
1904.43
e6/l
0.42
21
130
66
507
1.31
1.32
3.7
3.6
1.62
4.06
ratio
1.46
53
294
26
168
1.56
1.32
1.4
1.6
—
—
—
0
0
16
91
1.77
1.29
1.3
1.2
127.34
135.09
nmol/l
0.16
16
91
720
6782
1.11
1.28
12.8
11.6
0.00
0.00
e9/l
1.71
608
5547
74
581
1.29
1.27
3.4
2.7
9.31
10.36
g/l
1.68
64
526
28
186
1.51
1.26
1.5
1.3
40.38
29.64
u/l
0.67
23
153
14
77
1.82
1.25
1.1
1.2
—
—
—
0
0
27
179
1.52
1.24
1.1
1.3
—
—
nmol/l
—
0
0
23
147
1.57
1.23
1.5
1.4
—
—
—
0
0
308
2775
1.13
1.21
3.8
3.4
0.69
0.77
ug/l
1.83
234
1888
18
109
1.66
1.19
1.8
1.9
70.94
73.18
%
0.25
18
102
27
181
1.50
1.18
1.4
1.6
24.20
30.61
ng/l
0.38
27
181
102
842
1.22
1.16
3.4
2.7
1.15
1.20
%
0.25
102
836
25
166
1.51
1.15
3.6
4.6
—
—
—
0
0
47
352
1.34
1.14
1.2
1.2
56.56
55.15
u/ml
—
5
40
30
208
1.45
1.13
1.2
1.2
—
—
—
0
0
115
965
1.21
1.12
2.5
1.8
1.44
1.39
g/l
0.07
101
890
13
221
0.59
1.12
2.0
1.9
—
—
—
0
0
45
336
1.35
1.12
1.5
1.4
—
—
—
0
0
19
119
1.60
1.11
1.3
1.2
11.89
12.49
u/l
0.08
19
110
48
363
1.33
1.10
1.6
1.4
25.95
36.09
e6/l
0.17
42
270
16
96
1.67
1.10
1.3
1.8
—
—
—
0
0
21
137
1.54
1.05
4.1
5.3
27.05
35.90
u/ml
—
6
44
548
5138
1.10
1.04
3.6
3.3
135.73
86.49
e6/l
0.22
461
3936
18
114
1.59
1.02
1.4
1.4
13.33
13.30
u/l
0.01
18
108
24
164
1.47
0.99
1.3
1.4
—
—
—
0
0
13
76
1.72
0.99
1.2
1.1
1481.77
1663.62
miu/ml
0.25
13
76
24
165
1.46
0.97
1.2
1.2
—
—
—
0
0
19
124
1.54
0.97
1.3
1.1
—
72.46
—
0
7
10
174
0.57
0.96
1.0
1.2
—
—
—
0
0
211
1886
1.14
0.96
2.2
2.6
1.87
1.84
%
0.16
186
1683
176
1556
1.15
0.95
3.9
3.5
1.91
1.83
mmol/l
0.12
159
1341
24
166
1.45
0.94
1.3
1.5
—
—
—
0
0
26
183
1.43
0.94
1.1
1.3
0.18
0.28
nmol/l
0.46
19
140
8
145
0.55
0.93
1.1
1.1
—
—
—
0
0
134
1534
0.86
0.90
2.8
2.3
98.22
40.95
u/l
0.40
114
1296
615
5830
1.09
0.90
4.4
3.9
138.17
101.60
e6/l
0.22
485
4130
11
63
1.75
0.90
1.3
1.7
27.82
29.37
%
0.14
11
63
75
620
1.22
0.89
1.5
1.7
0.20
0.35
mg/l
2.86
37
285
32
426
0.75
0.88
1.3
1.3
—
—
—
0
0
24
169
1.43
0.87
1.2
1.4
8900.00
103565.02
e6/l
—
9
96
18
264
0.68
0.87
1.9
1.8
1.42
1.71
mmol/l
1.98
18
258
205
1844
1.13
0.86
2.2
2.7
8.17
7.87
umol/l
0.06
176
1630
33
247
1.34
0.85
1.0
1.1
—
—
—
0
0
33
248
1.34
0.84
1.1
1.1
0.71
1.25
u/ml
0.88
18
131
270
2475
1.11
0.82
2.2
1.8
—
—
—
0
0
66
545
1.22
0.81
3.5
3.5
1.35
1.38
mmol/l
0.11
66
535
22
155
1.42
0.81
1.4
1.4
174162.00
60968.25
e6/l
0.29
13
105
30
224
1.35
0.80
1.1
1.2
1.75
5.18
u/ml
1.54
12
93
179
1608
1.13
0.78
2.3
2.3
0.20
0.21
g/l
0.79
161
1504
0
26
0.00
0.78
0.0
1.2
—
0.02
—
0
26
20
140
1.43
0.77
3.3
2.0
4.60
4.15
mg/l
0.13
20
135
6
34
1.77
0.76
6.8
7.2
7.17
5.37
kpa
—
6
34
33
253
1.31
0.75
1.5
1.7
0.55
0.83
g/l
1.16
25
204
78
661
1.19
0.75
1.1
1.1
—
—
—
0
0
29
218
1.34
0.75
1.1
1.3
—
0.40
nmol/l
—
0
15
165
1480
1.13
0.75
8.4
7.3
9.27
9.97
mmol/l
0.72
154
1423
28
210
1.34
0.74
1.4
1.2
—
—
—
0
0
419
3948
1.08
0.71
2.6
2.4
—
—
—
0
0
50
409
1.23
0.70
1.9
2.1
2.41
17.24
iu/l
0.58
19
176
5
27
1.85
0.68
1.2
1.4
—
—
—
0
0
66
557
1.19
0.68
3.0
3.2
219.88
234.53
mg/l
0.14
25
228
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
21
154
1.37
0.65
1.2
1.2
—
—
—
0
0
6
103
0.58
0.62
2.3
1.4
87.67
83.22
umol/l
—
6
103
8
49
1.64
0.62
1.9
2.7
—
—
—
0
0
24
183
1.32
0.59
1.7
1.7
56.85
61.51
%
0.18
13
116
21
157
1.34
0.59
1.6
2.1
—
—
—
0
0
41
336
1.23
0.59
3.6
4.5
2.58
2.71
mmol/l
0.10
27
232
50
420
1.20
0.57
1.6
1.7
14394.60
12669.42
e6/l
0.16
35
298
25
318
0.78
0.55
3.0
4.0
23.83
25.81
mg/l
0.08
15
224
26
204
1.28
0.54
1.3
1.2
—
—
—
0
0
327
3089
1.07
0.53
3.5
2.9
534.19
529.74
mosm/kgh2o
0.13
299
2705
10
66
1.52
0.52
1.4
3.1
101.60
106.36
umol/l
—
5
39
293
2760
1.07
0.52
3.1
2.9
2.29
1.04
e6/l
0.37
184
1462
85
753
1.14
0.51
1.5
1.8
1.38
1.55
g/l
1.10
70
662
9
64
1.41
0.51
4.7
2.9
—
—
—
0
0
38
315
1.21
0.51
4.2
1.6
0.91
0.84
nmol/l
0.23
28
262
20
153
1.31
0.50
5.1
4.0
27.77
66.98
u/ml
1.12
20
153
1224
12039
1.06
0.49
25.3
21.4
332.08
331.89
g/l
0.31
1218
11972
130
1423
0.91
0.49
2.1
2.0
3.38
3.44
ratio
0.23
94
1117
94
1047
0.89
0.49
2.0
1.8
3.87
3.47
mmol/l
2.24
62
741
7
45
1.56
0.49
1.3
1.5
6.51
3.66
mmol/l
—
7
39
7
46
1.52
0.48
1.1
1.4
—
—
—
0
0
463
4441
1.06
0.47
3.5
3.2
0.25
0.43
e6/l
2.71
376
3266
228
2137
1.08
0.47
1.3
1.3
—
—
—
0
0
26
209
1.25
0.46
1.1
1.1
0.86
4.41
u/ml
—
10
107
537
5177
1.05
0.46
2.7
2.5
—
—
—
0
0
57
496
1.15
0.46
1.7
1.6
1222.90
995.57
mu/l
0.80
46
410
45
384
1.18
0.46
1.2
1.2
—
—
—
0
0
20
156
1.29
0.45
2.6
2.3
—
—
—
0
0
29
238
1.22
0.44
3.1
1.8
0.78
0.87
%
0.50
19
166
42
358
1.18
0.44
1.5
1.7
—
—
—
0
0
18
230
0.78
0.43
1.4
1.6
—
—
—
0
0
20
157
1.28
0.43
1.8
2.2
—
—
—
0
0
8
56
1.43
0.42
3.6
2.0
20.40
16.86
ug/l
—
8
48
52
454
1.15
0.41
1.3
1.2
68.57
91.35
titre
—
7
37
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
6.80
—
0
7
5
34
1.47
0.40
2.0
1.8
—
—
—
0
0
18
141
1.28
0.40
1.3
1.5
352.85
346.91
mu/l
0.03
13
110
43
371
1.16
0.40
5.8
4.7
—
—
—
0
0
25
205
1.22
0.39
1.2
1.2
—
—
—
0
0
16
124
1.29
0.38
1.4
1.4
—
—
—
0
0
5
36
1.39
0.38
2.2
1.7
—
—
—
0
0
18
225
0.80
0.38
1.4
1.5
—
—
—
0
0
15
116
1.30
0.37
1.0
1.2
—
—
—
0
0
9
70
1.29
0.36
4.7
2.7
—
—
—
0
0
18
222
0.81
0.34
1.3
1.4
1.43
1.28
mm
—
10
154
15
189
0.79
0.34
2.6
2.1
—
—
—
0
0
38
436
0.87
0.34
4.6
3.4
1.63
2.07
index
0.28
19
236
24
285
0.84
0.32
2.5
1.7
—
—
—
0
0
117
1090
1.08
0.32
1.7
1.4
—
—
—
0
0
14
110
1.27
0.31
1.1
1.3
—
—
—
0
0
7
96
0.73
0.31
1.3
2.7
15.84
16.50
%
—
7
96
23
193
1.19
0.31
1.0
1.1
10.36
2.32
eliau/ml
0.40
14
77
21
176
1.20
0.29
1.6
1.4
—
—
—
0
0
27
232
1.17
0.28
2.6
2.5
—
—
—
0
0
12
94
1.28
0.28
1.1
1.1
—
—
—
0
0
75
691
1.09
0.27
2.0
1.9
1.21
1.96
ug/l
0.48
66
608
111
1040
1.07
0.27
8.1
9.8
0.73
0.65
%
1.38
111
1033
8
64
1.25
0.27
1.1
1.2
—
0.12
g/l
—
0
6
9
121
0.74
0.27
1.0
1.5
13.32
13.65
umol/l
—
9
114
58
635
0.91
0.26
2.1
3.5
1110.38
6455.59
u/ml
0.66
50
555
5
73
0.68
0.26
1.2
1.9
4.38
6.00
nmol/l
—
5
63
37
329
1.13
0.26
3.5
3.4
7.54
7.57
mmol/l
0.02
37
323
11
138
0.80
0.25
1.0
1.1
—
—
—
0
0
38
340
1.12
0.24
4.8
3.5
0.75
0.81
nmol/l
0.81
33
286
52
475
1.10
0.24
3.0
3.0
1.80
1.60
mg/l
0.53
45
428
14
115
1.22
0.23
1.0
1.1
36.03
34.25
mmol/l
0.10
14
104
19
222
0.85
0.23
1.3
1.8
—
—
—
0
0
135
1284
1.06
0.22
1.4
1.4
—
—
—
0
0
7
93
0.75
0.22
1.0
1.1
—
—
—
0
0
12
146
0.82
0.22
1.1
1.0
—
—
—
0
0
5
41
1.22
0.22
9.0
3.9
—
—
—
0
0
17
144
1.18
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
0.04
—
0
5
0
10
0.00
0.21
0.0
1.0
—
50.90
—
0
10
1223
12126
1.03
0.21
22.8
20.6
13.61
13.68
%
1.03
1216
11953
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
5.47
—
0
12
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
0.66
—
0
12
440
4301
1.03
0.21
1.5
1.4
—
—
—
0
0
5
43
1.16
0.21
1.0
1.2
26.20
28.40
s
—
5
43
20
173
1.16
0.21
1.1
1.1
7.06
3.65
u/ml
—
5
74
0
13
0.00
0.21
0.0
1.1
—
0.24
—
0
5
0
13
0.00
0.21
0.0
1.1
—
0.10
—
0
5
0
13
0.00
0.21
0.0
1.1
—
0.17
—
0
8
94
995
0.94
0.20
8.4
9.7
24.72
24.26
mmol/l
1.11
94
977
46
422
1.09
0.20
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
91.43
—
0
14
84
791
1.07
0.20
4.8
3.6
1.02
1.02
ratio
1.23
79
727
18
155
1.16
0.20
1.1
1.0
0.14
0.32
u/ml
—
5
53
23
203
1.13
0.19
1.1
1.1
0.72
1.01
u/ml
—
10
98
25
280
0.89
0.18
3.5
4.0
19.84
29.90
u/ml
1.21
25
274
561
5516
1.03
0.18
3.4
3.2
—
—
—
0
0
63
672
0.94
0.18
1.7
1.8
—
—
—
0
0
63
591
1.07
0.17
1.4
1.9
20.04
21.08
s
1.51
52
533
23
205
1.12
0.17
1.0
1.1
0.28
1.33
u/ml
—
7
85
38
350
1.09
0.16
4.3
4.0
—
—
—
0
0
130
1251
1.04
0.15
4.8
3.9
—
—
—
0
0
113
1084
1.05
0.15
7.9
9.4
1.35
1.30
%
0.27
113
1074
6
77
0.78
0.15
13.0
17.8
573.17
857.95
nmol/l
—
6
77
9
80
1.13
0.15
1.3
1.7
—
—
—
0
0
9
81
1.11
0.15
2.1
3.0
1488.89
1864.93
ml
—
9
74
31
286
1.09
0.13
1.9
1.4
—
—
—
0
0
46
432
1.07
0.13
1.2
1.2
—
—
—
0
0
27
294
0.92
0.13
1.3
1.5
76.46
62.84
ug/l
0.42
20
244
28
258
1.09
0.12
1.9
1.4
148.80
158.43
au/ml
—
5
72
44
414
1.06
0.12
1.2
1.2
—
—
—
0
0
15
168
0.89
0.11
1.9
1.5
—
—
—
0
0
31
333
0.93
0.11
3.0
2.7
16.03
16.11
%
0.05
31
327
14
124
1.13
0.11
1.0
1.0
276.22
292.33
ng/l
—
9
83
27
250
1.08
0.11
1.1
1.1
6.97
19.37
au/ml
—
6
66
251
2557
0.98
0.10
3.3
3.0
2.80
2.45
e6/l
0.26
145
1252
34
319
1.07
0.10
1.5
1.2
—
—
—
0
0
14
125
1.12
0.10
1.0
1.0
544.00
717.67
ng/l
—
9
81
31
330
0.94
0.09
1.7
1.8
—
—
—
0
0
10
87
1.15
0.09
1.6
1.2
—
—
—
0
0
176
1723
1.02
0.09
3.3
4.4
7.83
20.45
ug/l
1.34
137
1410
14
126
1.11
0.09
1.3
1.2
8.21
0.64
u/ml
—
9
66
46
439
1.05
0.09
1.1
1.1
0.71
0.63
ratio
—
5
68
18
165
1.09
0.08
1.1
1.2
—
—
—
0
0
40
420
0.95
0.08
1.5
1.6
—
—
—
0
0
39
371
1.05
0.08
2.5
2.3
221.57
98.27
ug/min
0.51
23
224
7
65
1.08
0.08
1.1
1.2
409.86
240.59
iu/ml
—
7
65
7
65
1.08
0.08
1.3
1.9
38.59
40.39
g/l
—
7
65
6
70
0.86
0.07
1.2
1.2
14.83
10.91
mm/h
—
6
70
118
1153
1.03
0.07
1.3
1.4
—
—
—
0
0
6
72
0.83
0.07
2.0
1.4
—
1.64
—
0
11
9
100
0.90
0.06
3.0
1.9
83.92
103.86
ng/l
—
9
100
9
104
0.86
0.06
1.6
2.4
7.98
8.54
mmol/l
—
9
104
49
473
1.04
0.06
1.1
1.2
1.55
1.57
g/l
0.22
49
473
34
325
1.05
0.06
1.2
1.2
—
—
—
0
0
32
335
0.95
0.06
3.1
3.0
55.91
58.13
%
0.38
32
335
137
1394
0.98
0.06
8.3
8.8
—
—
—
0
0
41
425
0.96
0.05
1.9
1.7
—
—
—
0
0
20
189
1.06
0.04
1.1
1.1
1.16
2.28
u/ml
—
10
93
110
1082
1.02
0.04
8.4
9.6
94.79
93.89
%
1.91
110
1074
28
269
1.04
0.04
3.1
3.0
3.92
4.09
e9/l
0.19
28
269
19
180
1.06
0.04
1.2
1.2
—
—
—
0
0
38
392
0.97
0.04
1.7
1.7
—
—
—
0
0
11
119
0.92
0.04
1.5
1.1
—
—
—
0
0
41
422
0.97
0.03
1.7
1.7
—
—
—
0
0
41
422
0.97
0.03
1.7
1.7
—
—
—
0
0
146
1476
0.99
0.03
6.8
7.6
1.38
1.32
mmol/l
0.32
146
1448
10
108
0.93
0.03
1.5
1.1
—
—
—
0
0
140
1413
0.99
0.02
1.4
1.4
—
—
—
0
0
27
278
0.97
0.02
1.4
1.6
—
—
—
0
0
17
177
0.96
0.01
1.4
1.5
5.16
6.44
mmol/l
1.57
17
168
19
184
1.03
0.00
4.3
5.4
7.59
7.18
mmol/l
0.17
14
157
13
129
1.01
0.00
1.5
1.6
48.14
32.54
%
—
7
80
29
285
1.02
0.00
1.2
1.2
301.80
252.17
u/ml
—
10
160
30
305
0.98
0.00
2.2
2.4
—
—
—
0
0
20
196
1.02
0.00
1.6
1.9
31.75
19.16
ug/l
0.61
20
191
34
344
0.99
0.00
1.2
1.5
63.71
232.98
pmol/l
2.61
34
338
25
252
0.99
0.00
1.0
1.0
—
—
—
0
0
401
4007
1.00
0.00
4.0
4.1
88.42
89.51
%
0.37
391
3922
0
5
0.00
0.00
0.0
2.4
—
4.74
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.4
2.5
0.65
0.61
mmol/l
—
5
50
0
8
0.00
-0.00
0.0
1.5
—
0.06
—
0
8
7
78
0.90
-0.00
1.3
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
0.15
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
234.00
—
0
6
20
200
1.00
-0.00
1.4
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
355.50
—
0
8
6
64
0.94
-0.00
1.5
1.3
147.83
171.71
mmol/24h
—
6
64
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.0
2.2
0.00
0.06
estimate
—
5
54
0
8
0.00
-0.00
0.0
1.1
—
0.03
—
0
8

Mortality – FinRegistry

Association

Association between endpoint H7_VITROPACIT and mortality.

Females

Parameter HR [95% CI] p-value
H7_VITROPACIT 0.973 [0.87, 1.09] 0.646
Birth year 0.995 [0.99, 1.0] 0.253

During the follow-up period (1.1.1998 — 31.12.2019), 644 out of 4409 females with H7_VITROPACIT died.

Males

Parameter HR [95% CI] p-value
H7_VITROPACIT 0.898 [0.79, 1.02] 0.095
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 756 out of 3373 males with H7_VITROPACIT died.

Mortality risk

Mortality risk for people of age

years, who have H7_VITROPACIT.

N-year risk Females Males
1 0.087% 0.164%
5 0.541% 1.043%
10 1.374% 2.506%
15 2.673% 4.825%
20 4.5% 8.075%

Relationships between endpoints

Index endpoint: H7_VITROPACIT – Other vitreous opacities

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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