Asymptomatic human immunodeficiency virus [HIV] infection status

Z21_ASYMP_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV_INFECTION_STATUS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Z21
  • Cause of death: ICD-10 Z21

2 out of 7 registries used, show all original rules.

223

4. Check minimum number of events

None

223

5. Include endpoints

None

223

6. Filter based on genotype QC (FinnGen only)

191

Control definitions (FinnGen only)

Control exclude
Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_COMMUNICAB_DISEA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1034 286 725
Only index persons 929 274 655
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.01 0.03
Median age at first event (years)
Whole population 37.15 31.93 39.40
Only index persons 36.71 31.33 38.96

-FinnGen-

Key figures

All Female Male
Number of individuals 191 32 159
Unadjusted period prevalence (%) 0.06 0.01 0.07
Median age at first event (years) 39.60 38.98 39.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
216
Matched controls
2160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
312.8
216
*
WW200
NOMESCO Finland
Immunization
320.8
307.7
172
26
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
4709.5
257.1
197
5
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
53.3
199.2
142
75
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
1066.2
148.7
129
*
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
23.4
114.1
101
78
Z25.1
ICD-10 Finland
Need for immunization against influenza
40.0
100.4
65
23
Z3231
NOMESCO Finland
Registered nurse
11.6
73.0
148
342
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
675.3
55.1
52
*
Z2221
NOMESCO Finland
Medical doctor
7.8
52.2
126
327
A63.0
ICD-10 Finland
Anogenital (venereal) warts
13.0
38.5
40
37
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
424.5
37.2
36
*
A51.0
ICD-10 Finland
Primary genital syphilis
424.5
37.2
36
*
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
+∞
32.1
30
*
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
37.6
27.9
35
11
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
27.7
26
*
Y25
ICPC
Fear sexually transm disease male
10.3
27.6
33
37
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
9.1
26.3
35
45
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
23.3
22
*
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
256.0
23.1
23
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
22.0
141
685
A54.5
ICD-10 Finland
Gonococcal pharyngitis
+∞
20.1
19
*
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
19.0
18
*
TAB00
NOMESCO Finland
Lumbar puncture
6.7
17.5
30
51
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.2
17.4
40
90
B18.2
ICD-10 Finland
Chronic viral hepatitis C
18.3
17.0
26
16
C10AA07
ATC
rosuvastatin; oral
3.3
16.8
113
538
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.6
16.8
35
72
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
4.8
16.6
43
107
Z01.2
ICD-10 Finland
Dental examination
3.0
13.6
128
712
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
13.4
13.5
23
19
WX110, ,
SPAT
4.9
13.4
32
74
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.8
13.3
26
50
N05CF01
ATC
zopiclone; oral
3.0
13.1
86
392
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
6.3
13.0
23
40
J05AB01
ATC
aciclovir; systemic
3.2
12.3
61
236
ULA02
NOMESCO Finland
Kolposcopy
5.4
11.5
24
49
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.0
11.1
63
262
R4110
NOMESCO Finland
Physiotherapy
2.7
10.7
78
370
P19
ICPC
Drug abuse
115.4
10.5
11
*
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
10.5
10
*
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
34.4
10.5
13
*
TLC02
NOMESCO Finland
Simple extraction of IUD
24.8
10.4
14
6
Z3226
NOMESCO Finland
Physiotherapist
3.2
10.4
49
183
ZXE00
NOMESCO Finland
One hour or less
2.6
10.4
93
488
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
10.8
10.2
19
19
Z3232
NOMESCO Finland
Midwife
5.1
10.0
22
47
S02.51
ICD-10 Finland
Fracture of tooth, open
3.6
9.9
36
114
ZX114
NOMESCO Finland
Intramuscular
14.3
9.8
16
12
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.1
9.8
29
79
WYA30, ,
SPAT
22.9
9.5
13
6
N05CD07
ATC
temazepam; oral
3.9
9.5
30
86
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
+∞
9.4
9
*
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.6
9.3
69
327
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
12.2
9.2
16
14
EB1AA, ,
SPAT
3.8
8.7
28
81
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
4.6
8.6
21
49
Z2446
NOMESCO Finland
Social worker
4.3
8.6
23
58
K02.9
ICD-10 Finland
Dental caries, unspecified
11.4
8.4
15
14
Z71.8
ICD-10 Finland
Other specified counselling
2.3
8.1
85
469
N06AB04
ATC
citalopram; systemic
2.7
8.1
53
235
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.4
7.9
72
373
K02.2
ICD-10 Finland
Caries of cementum
4.7
7.6
18
41
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
82.8
7.5
8
*
N05BB01
ATC
hydroxyzine; systemic
4.3
7.2
19
47
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
31.1
7.2
9
*
P18
ICPC
Medication abuse
31.1
7.2
9
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
7.2
79
440
KMAK, ,
NOMESCO Finland
2.2
7.1
132
903
TLC00
NOMESCO Finland
Insertion of intrauterine device
6.7
7.1
17
27
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
3.6
7.1
24
72
D01AE16
ATC
amorolfine; topical
3.2
7.0
29
99
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
14.4
7.0
11
8
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.0
6.9
18
32
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
6.5
6.9
17
28
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.5
6.9
50
232
N05BA04
ATC
oxazepam; oral
2.3
6.8
61
311
D11
ICPC
Diarrhoea
2.7
6.6
38
156
F43.29
ICD-10 Finland
Adaptation disorder UNS
6.6
6.6
16
26
J05AB11
ATC
valaciclovir; oral
2.7
6.5
38
158
D10AF01
ATC
clindamycin; topical
3.9
6.4
19
52
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
6.4
39
166
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
6.3
38
160
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
6.3
6
*
A51.4
ICD-10 Finland
Other secondary syphilis
+∞
6.3
6
*
B20.9
ICD-10 Finland
HIV disease resulting in unspecified infectious or parasitic disease
+∞
6.3
6
*
Y71
ICPC
Gonorrhoea male
+∞
6.3
6
*
J01MA12
ATC
levofloxacin; systemic
2.5
6.1
44
203
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
2.7
6.1
34
138

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
202
49
621.61
307.65
9.1
5.2
133.46
359.21
mg/l
1.57
195
24
193
15
1199.96
307.65
2.8
2.2
34.00
41.99
%
1.34
193
15
178
13
773.62
307.65
3.2
3.4
34.44
36.40
%
—
45
5
174
162
51.10
187.69
5.8
1.6
—
—
—
0
0
203
260
114.11
182.92
6.5
1.7
—
—
—
0
0
173
174
45.92
177.72
3.1
1.7
—
—
—
0
0
211
590
111.74
99.81
17.4
6.7
—
—
—
0
0
189
606
17.95
68.44
6.9
3.5
30.84
94.55
e6/l
0.54
89
431
175
520
13.46
67.56
13.6
5.8
—
—
—
0
0
199
742
22.37
60.30
17.9
3.7
31.29
35.43
u/l
1.37
199
707
200
775
22.34
57.48
5.1
2.8
6.06
6.11
ph
0.17
54
485
170
563
10.48
56.15
5.2
2.3
—
0.33
—
0
6
187
715
13.03
52.56
6.9
5.9
39.65
36.92
g/l
11.89
187
691
47
45
13.07
44.46
1.0
1.1
—
—
—
0
0
202
935
18.90
43.93
5.8
3.0
0.00
0.00
estimate
-0.00
18
172
202
942
18.66
43.35
5.8
3.1
0.00
0.00
estimate
-0.00
18
171
202
948
18.45
42.86
5.9
3.1
0.00
0.02
estimate
0.50
18
152
216
1356
+∞
40.92
15.3
9.1
75.36
78.49
u/l
0.91
216
1303
45
47
11.83
40.02
1.1
1.1
—
—
—
0
0
45
59
9.37
33.64
1.1
1.4
178.57
213.74
miu/ml
0.20
14
30
198
1060
11.42
31.86
8.7
6.7
6.05
6.70
mmol/l
7.99
198
1021
175
846
6.63
31.28
2.6
1.9
1.49
1.57
mmol/l
0.58
169
744
37
11
40.21
29.85
2.3
2.7
15.22
13.18
%
0.28
37
11
33
7
55.27
28.36
2.5
1.9
35.79
21.14
%
—
33
7
112
455
4.04
22.98
4.3
2.8
0.08
0.36
e6/l
4.07
82
327
31
42
8.45
22.24
1.9
3.5
3.60
2.78
index
—
5
27
85
304
3.96
20.58
1.5
1.7
—
—
—
0
0
116
528
3.59
19.22
4.2
2.9
54.79
42.69
e6/l
0.13
88
399
27
20
15.25
16.50
2.4
1.6
—
—
—
0
0
71
259
3.59
16.19
3.6
2.6
3.67
1.23
e6/l
0.39
27
111
47
996
0.33
10.99
4.6
3.0
—
—
—
0
0
81
392
2.71
10.69
1.4
1.5
19.21
20.26
nmol/l
0.31
76
354
201
1599
4.70
9.08
34.5
17.0
13.30
13.39
%
0.56
201
1586
51
233
2.56
7.25
1.8
2.5
22.69
25.25
%
0.48
51
227
26
81
3.51
7.24
3.5
1.7
—
—
—
0
0
10
5
20.86
7.20
2.1
4.2
38.30
31.40
%
—
10
5
18
44
4.37
6.96
3.3
2.6
50.67
58.35
%
1.76
18
44
23
68
3.67
6.91
1.3
1.1
—
—
—
0
0
17
32
5.67
6.30
3.4
2.9
2.94
4.85
e9/l
2.84
17
32
54
272
2.31
6.13
1.8
2.5
14.33
14.46
umol/l
0.04
54
260
216
2012
+∞
6.06
34.7
17.1
84.25
79.90
umol/l
2.44
216
1997
19
56
3.62
5.73
2.5
1.1
—
—
—
0
0
46
223
2.35
5.67
1.8
1.6
—
—
—
0
0
216
2019
+∞
5.65
27.8
11.5
34.39
32.92
u/l
0.46
216
1993
50
255
2.25
5.47
1.8
2.5
2.54
2.34
g/l
1.36
50
243
18
54
3.55
5.29
1.3
1.3
—
—
—
0
0
59
335
2.05
4.87
2.3
2.1
2.62
2.89
mg/l
0.36
52
300
17
52
3.46
4.86
1.5
1.6
—
—
—
0
0
9
11
8.48
4.60
7.6
3.2
43.86
23.29
mu/l
—
9
11
34
158
2.37
4.58
1.6
2.5
1.70
1.85
%
0.52
34
151
36
177
2.24
4.26
12.4
15.2
—
—
—
0
0
11
22
5.21
4.06
1.1
1.0
—
—
—
0
0
97
682
1.77
4.02
2.0
1.8
94.37
97.36
pmol/l
0.38
66
382
14
362
0.34
3.92
1.4
1.4
—
—
—
0
0
73
475
1.81
3.91
5.3
4.8
—
—
—
0
0
11
25
4.58
3.67
1.1
1.0
—
—
—
0
0
14
46
3.19
3.60
3.1
2.2
—
—
—
0
0
129
1010
1.69
3.44
5.8
3.4
—
5.38
—
0
16
13
38
3.57
3.37
2.5
1.5
—
—
—
0
0
30
151
2.15
3.35
1.8
1.8
0.24
0.37
mg/l
1.04
19
75
25
118
2.27
3.25
1.1
2.9
64.55
74.15
e9/l
0.88
11
78
10
24
4.32
3.24
1.0
1.3
—
—
—
0
0
9
20
4.65
3.15
3.1
1.8
—
—
—
0
0
25
120
2.23
3.13
1.4
1.4
—
—
—
0
0
216
2083
+∞
3.03
38.9
21.5
42.49
42.59
%
0.14
216
2068
216
2083
+∞
3.03
37.4
20.6
6.18
6.62
e9/l
4.13
216
2055
216
2083
+∞
3.03
37.4
20.5
4.56
4.75
e12/l
6.84
216
2053
216
2083
+∞
3.03
37.3
20.5
31.76
30.44
pg
17.37
216
2072
216
2082
+∞
3.02
37.4
20.5
93.97
90.53
fl
17.75
216
2071
216
2081
+∞
3.01
37.4
20.6
242.00
247.93
e9/l
0.71
216
2056
32
174
1.99
2.92
2.3
3.9
0.32
1.89
mmol/l
1.30
25
159
70
484
1.66
2.91
3.8
4.1
7.39
7.40
ph
0.46
43
349
32
176
1.96
2.83
2.3
4.1
7.35
7.38
ph
2.43
20
97
216
2085
+∞
2.82
37.6
20.6
143.77
143.61
g/l
0.05
216
2072
53
343
1.72
2.80
3.0
3.6
207.19
339.92
ng/l
0.35
43
248
25
126
2.11
2.79
1.4
1.4
—
—
—
0
0
193
1738
2.04
2.72
35.8
17.0
336.72
335.49
g/l
1.11
193
1731
12
41
3.04
2.66
2.6
1.4
35.14
26.61
e6/l
—
7
31
78
565
1.60
2.65
3.2
3.6
68.11
55.18
mg/l
0.20
48
391
25
129
2.06
2.63
1.4
1.4
—
—
—
0
0
25
129
2.06
2.63
1.4
1.4
—
—
—
0
0
25
129
2.06
2.63
1.4
1.4
—
—
—
0
0
7
15
4.78
2.62
3.9
1.6
—
—
—
0
0
6
11
5.57
2.56
1.0
1.1
512.67
246.95
iu/ml
—
6
11
21
104
2.13
2.46
1.3
1.2
—
—
—
0
0
45
289
1.70
2.43
3.7
2.4
—
—
—
0
0
20
98
2.15
2.40
1.5
1.4
—
—
—
0
0
10
33
3.13
2.39
3.8
3.5
17.91
5.23
u/ml
—
10
33
9
30
3.08
2.17
2.1
2.7
9.44
9.28
kpa
—
9
30
9
30
3.08
2.17
2.1
2.7
4.82
5.01
kpa
—
9
30
38
244
1.68
2.05
1.5
1.5
—
—
—
0
0
7
21
3.41
1.98
1.1
1.1
—
—
—
0
0
10
39
2.64
1.97
2.7
2.5
—
—
—
0
0
5
11
4.62
1.95
1.0
1.1
157.80
179.86
nmol/l
—
5
11
11
46
2.47
1.88
1.1
1.2
715.82
475.30
mg/l
0.61
11
46
183
1951
0.59
1.88
11.5
11.8
—
—
—
0
0
6
18
3.40
1.76
9.0
12.3
0.50
0.55
mmol/l
—
6
18
75
581
1.45
1.75
3.7
4.2
10.24
8.64
mg/mmol
0.15
43
394
15
75
2.07
1.74
1.1
1.2
—
—
—
0
0
6
143
0.40
1.58
1.2
1.1
1.42
1.46
g/l
—
6
143
6
144
0.40
1.58
1.2
1.1
0.78
0.90
g/l
—
6
144
52
385
1.46
1.52
1.5
1.4
3.12
2.61
g/l
0.44
23
270
40
282
1.51
1.48
1.3
1.4
260.00
402.11
titre
—
6
57
139
1542
0.72
1.44
4.9
3.6
60.58
53.85
u/l
0.42
131
1497
6
24
2.54
1.31
1.0
1.1
—
—
—
0
0
67
538
1.36
1.22
2.0
2.4
—
—
—
0
0
59
726
0.74
1.14
5.6
2.8
0.00
0.00
estimate
-0.00
17
145
23
153
1.56
1.12
1.3
1.2
—
—
—
0
0
93
793
1.30
1.11
8.0
10.2
1.20
1.20
mmol/l
0.32
84
709
8
41
1.99
1.10
1.3
1.8
0.57
0.74
g/l
—
8
34
8
41
1.99
1.10
1.1
1.2
3.82
3.76
mmol/l
—
8
41
53
656
0.75
1.06
2.3
3.1
14.52
33.57
ng/l
2.23
26
412
10
176
0.55
1.05
1.0
1.1
—
—
—
0
0
9
47
1.95
1.03
2.1
2.6
7.42
7.41
ph
—
9
47
32
235
1.42
0.99
1.2
1.3
—
—
—
0
0
0
30
0.00
0.98
0.0
3.0
—
25.33
—
0
23
18
117
1.59
0.97
1.4
1.1
—
—
—
0
0
0
31
0.00
0.97
0.0
4.0
—
3.60
—
0
31
22
152
1.50
0.92
7.5
5.6
0.00
0.88
%
—
5
51
6
28
2.17
0.92
1.0
1.1
—
—
—
0
0
6
29
2.10
0.90
1.5
1.4
—
—
—
0
0
21
145
1.50
0.89
7.5
5.9
0.00
0.68
%
—
5
46
6
30
2.03
0.87
1.5
1.6
—
—
—
0
0
49
396
1.31
0.85
3.3
2.5
16.81
14.76
nmol/l
1.13
49
379
89
1008
0.80
0.84
3.5
3.6
1.55
1.43
ug/l
0.30
83
941
18
122
1.52
0.83
1.2
1.3
—
—
—
0
0
62
519
1.27
0.83
6.0
3.8
2.36
2.35
mmol/l
0.35
56
483
14
210
0.64
0.82
1.6
1.6
—
—
—
0
0
0
24
0.00
0.79
0.0
3.3
—
7.02
—
0
24
0
25
0.00
0.79
0.0
1.8
—
—
—
0
0
0
26
0.00
0.79
0.0
3.2
—
—
—
0
0
0
26
0.00
0.79
0.0
1.8
—
0.17
—
0
20
0
27
0.00
0.78
0.0
2.9
—
—
—
0
0
84
736
1.23
0.75
8.0
10.7
1.16
1.17
inr
0.12
70
611
33
258
1.33
0.73
13.3
11.7
104.45
104.17
mmol/l
0.12
33
258
27
205
1.36
0.71
15.1
16.8
-0.03
0.92
mmol/l
0.49
22
170
48
397
1.27
0.70
2.1
1.8
—
—
—
0
0
27
206
1.36
0.69
15.2
16.8
7.39
7.42
ph
—
7
112
21
155
1.39
0.66
2.6
1.9
230.95
225.56
pmol/l
0.12
21
149
54
629
0.81
0.64
2.7
2.5
0.93
0.64
ug/l
0.42
38
303
6
105
0.56
0.63
2.0
1.7
—
—
—
0
0
9
138
0.64
0.63
2.2
1.4
2771.78
434.11
u/ml
—
9
130
39
470
0.79
0.62
7.4
5.1
—
—
—
0
0
13
88
1.51
0.62
1.8
2.3
20.54
21.48
s
0.46
13
80
43
511
0.80
0.61
1.5
2.6
349.78
357.47
umol/l
0.25
37
471
0
20
0.00
0.60
0.0
1.0
—
0.43
—
0
7
0
20
0.00
0.60
0.0
1.1
—
0.33
—
0
6
7
114
0.60
0.59
2.0
4.0
145.71
135.58
g/l
—
7
114
15
106
1.45
0.59
2.5
4.6
79.33
86.86
ng/l
0.21
15
100
8
53
1.53
0.59
1.1
1.3
—
—
—
0
0
45
529
0.81
0.58
1.3
1.4
—
—
—
0
0
36
297
1.25
0.55
1.6
1.7
332.58
42238704.73
pmol/l
0.50
31
277
27
335
0.78
0.55
1.4
1.3
27.83
24.47
iu/ml
—
6
107
32
261
1.27
0.54
2.0
2.4
—
—
—
0
0
21
266
0.77
0.50
1.6
1.4
—
—
—
0
0
7
107
0.64
0.50
2.4
3.1
1.25
1.22
mmol/l
—
7
99
16
119
1.37
0.50
8.4
3.3
—
—
—
0
0
11
77
1.45
0.46
1.2
1.3
—
—
—
0
0
16
207
0.75
0.45
1.2
1.4
—
—
—
0
0
8
58
1.39
0.42
1.5
2.4
23.19
24.65
mmol/l
—
8
58
0
17
0.00
0.41
0.0
1.9
—
1.06
—
0
11
5
34
1.48
0.40
1.0
1.2
—
—
—
0
0
49
552
0.85
0.40
4.9
2.3
0.00
0.01
estimate
0.50
17
139
0
18
0.00
0.40
0.0
1.1
—
0.39
—
0
5
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
2.4
—
33.78
—
0
18
5
35
1.44
0.39
3.0
2.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
5
76
0.65
0.36
1.2
1.5
21.65
15.69
iu/l
—
5
62
17
136
1.27
0.35
1.2
1.2
—
23.61
—
0
10
22
182
1.23
0.35
17.8
18.3
117.73
126.41
g/l
1.30
22
177
12
91
1.34
0.34
1.3
1.7
—
8.80
—
0
6
67
614
1.13
0.33
2.2
1.9
—
—
—
0
0
16
128
1.27
0.33
1.5
1.5
1.18
1.30
g/l
0.16
16
121
46
411
1.15
0.32
1.8
1.9
2.02
1.18
mg/l
0.41
38
319
25
293
0.83
0.32
1.4
1.3
5.92
4.74
u/ml
—
6
125
12
93
1.31
0.30
1.2
2.4
—
—
—
0
0
10
130
0.76
0.30
1.9
2.3
0.05
0.17
e6/l
—
10
125
7
56
1.26
0.29
1.0
2.9
0.71
1.03
nmol/l
—
7
51
62
571
1.12
0.28
3.5
3.3
64.00
73.10
u/l
0.37
62
544
9
73
1.24
0.26
1.1
1.2
—
—
—
0
0
73
779
0.90
0.25
2.4
2.8
—
—
estimate
—
0
0
6
85
0.70
0.24
1.3
3.2
—
—
—
0
0
25
282
0.87
0.22
1.2
1.5
—
—
—
0
0
8
102
0.78
0.21
1.9
3.1
0.61
0.64
%
—
8
102
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
3.9
—
40.50
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
7.8
—
11.50
—
0
10
0
12
0.00
0.21
0.0
1.3
—
0.00
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
4.08
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
105.08
—
0
13
0
13
0.00
0.21
0.0
1.5
—
2245.77
—
0
13
0
13
0.00
0.21
0.0
2.8
—
1.19
—
0
13
135
1308
1.09
0.20
3.3
3.7
13.84
14.55
pmol/l
3.32
129
1227
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
10
121
0.82
0.18
1.8
3.0
7.41
7.42
ph
—
10
100
8
98
0.81
0.14
1.1
1.0
—
—
—
0
0
5
45
1.11
0.10
1.2
2.8
62.28
157.65
mg/l
—
5
40
5
45
1.11
0.10
1.2
2.8
47.36
64.77
mg/l
—
5
40
6
56
1.07
0.08
1.2
1.5
203.17
245.31
ug/g
—
6
36
7
64
1.10
0.08
1.0
1.1
—
—
—
0
0
7
64
1.10
0.08
1.0
1.1
—
—
—
0
0
22
207
1.07
0.06
1.4
1.2
—
—
—
0
0
48
468
1.03
0.04
6.2
3.2
0.00
0.01
estimate
0.50
18
162
41
404
1.02
0.00
4.3
3.0
1.02
1.02
kg/l
0.67
30
269
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
-0.00
2.0
2.9
404.70
124.54
ng/l
—
10
85
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
59.60
—
0
5
0
9
0.00
-0.00
0.0
8.8
—
6.76
—
0
9
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.7
—
25.47
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
77.00
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
2.63
—
0
7
0
9
0.00
-0.00
0.0
4.4
—
9.86
—
0
9
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
0.67
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
82.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
2.86
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
2.06
—
0
7
7
76
0.92
-0.00
1.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
1.37
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
16.87
—
0
9
0
5
0.00
-0.00
0.0
13.6
—
4.56
—
0
5
0
7
0.00
-0.00
0.0
11.1
—
17.76
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
12.07
—
0
5

Mortality – FinRegistry

Association

Association between endpoint Z21_ASYMP_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV_INFECTION_STATUS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
Z21_ASYMP_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV_INFECTION_STATUS 2.926 [2.33, 3.68] < 0.001
Birth year 0.985 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 116 out of 694 males with Z21_ASYMP_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV_INFECTION_STATUS died.

Mortality risk

Mortality risk for people of age

years, who have Z21_ASYMP_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV_INFECTION_STATUS.

N-year risk Females Males
1 No data 0.587%
5 No data 3.198%
10 No data 7.823%
15 No data 14.841%
20 No data 24.18%

Relationships between endpoints

Index endpoint: Z21_ASYMP_HUMAN_IMMUNODEFICIENCY_VIRUS_HIV_INFECTION_STATUS – Asymptomatic human immunodeficiency virus [HIV] infection status

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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