Other diseases of gallbladder

K11_GALLBLAOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K82
  • Hospital discharge: ICD-9 575[3-9]
  • Hospital discharge: ICD-8 57600|57602|57604
  • Cause of death: ICD-10 K82
  • Cause of death: ICD-9 575[3-9]
  • Cause of death: ICD-8 57600|57602|57604

2 out of 7 registries used, show all original rules.

2050

4. Check minimum number of events

None

2050

5. Include endpoints

None

2050

6. Filter based on genotype QC (FinnGen only)

1821

Control definitions (FinnGen only)

Control exclude
K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K80-K87
Name in latin
Alii morbi vesicae biliaris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14816 9612 5039
Only index persons 11458 7755 3703
Unadjusted period prevalence (%)
Whole population 0.23 0.28 0.14
Only index persons 0.24 0.29 0.14
Median age at first event (years)
Whole population 53.44 50.94 58.14
Only index persons 50.54 48.38 55.05

-FinnGen-

Key figures

All Female Male
Number of individuals 1821 1136 685
Unadjusted period prevalence (%) 0.37 0.40 0.31
Median age at first event (years) 50.89 46.59 58.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1893
Matched controls
18930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K82.9
ICD-10 Finland
Disease of gallbladder, unspecified
+∞
320.1
298
*
57600
ICD-8 Finland
Other diseases of gallbladder and biliary, Cholesterosis vesicae felleae
+∞
307.7
392
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
180.3
307.7
432
31
K82.8
ICD-10 Finland
Other specified diseases of gallbladder
+∞
307.7
412
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
918.5
307.7
659
11
JKA20
NOMESCO Finland
Cholecystectomy
43.7
273.3
164
41
K82.4
ICD-10 Finland
Cholesterolosis of gallbladder
+∞
240.9
226
*
K82.2
ICD-10 Finland
Perforation of gallbladder
+∞
214.8
202
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
25.6
192.8
136
57
UJK02
NOMESCO Finland
ERCP
56.7
171.6
97
18
5756A
ICD-9 Finland
Other disorders of gallbladder, Cholesterolosis of gallbladder
+∞
170.4
161
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.4
147.2
932
4215
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
377.1
141.9
141
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.1
134.0
320
729
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.7
128.1
518
1745
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
59.2
112.3
63
11
6662
FHL
Cholecystectomy
233.4
107.8
110
5
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
344.6
99.0
99
*
6663
FHL
Cholecystectomy and cholangiography
497.4
96.3
95
*
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
46.3
91.5
54
12
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
41.1
85.7
52
13
K82.0
ICD-10 Finland
Obstruction of gallbladder
+∞
81.9
78
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
80.9
732
3731
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
75.9
356
1280
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
724.9
71.6
70
*
K80.8
ICD-10 Finland
Other cholelithiasis
27.7
67.5
46
17
K83.0
ICD-10 Finland
Cholangitis
+∞
67.1
64
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.2
65.9
89
113
A02BC05
ATC
esomeprazole; systemic
2.2
63.0
887
5343
57409
ICD-8 Finland
Cholelithiasis, Unspecified
+∞
59.7
57
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
59.6
320
1231
K81.0
ICD-10 Finland
Acute cholecystitis
96.2
59.2
65
7
5759X
ICD-9 Finland
Other disorders of gallbladder, Unspecified disorder of gallbladder
+∞
56.5
54
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
55.3
246
849
K85
ICD-10 Finland
Acute pancreatitis
273.2
52.4
53
*
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
+∞
51.3
49
*
A02BC02
ATC
pantoprazole; systemic
2.2
48.5
1393
10598
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
69.3
47.3
54
8
K81.9
ICD-10 Finland
Cholecystitis, unspecified
+∞
46.0
44
*
N02AX02
ATC
tramadol; systemic, rectal
2.0
45.6
899
5924
K83.1
ICD-10 Finland
Obstruction of bile duct
160.6
45.0
47
*
K30
ICD-10 Finland
Functional dyspepsia
2.7
44.1
276
1140
WX402
NOMESCO Finland
General anaesthesia
2.2
44.0
466
2436
UJF32
NOMESCO Finland
Coloscopy
2.1
42.9
587
3381
5758X
ICD-9 Finland
Other disorders of gallbladder, Other specified disorders of gallbladder
+∞
42.9
41
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
42.0
612
3602
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
+∞
41.8
40
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
15.5
40.0
35
23
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
+∞
39.7
38
*
A05AA02
ATC
ursodeoxycholic acid; oral
7.9
39.2
54
70
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
38.6
519
2952
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
38.4
380
1922
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
38.2
622
3782
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
+∞
35.5
34
*
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
7.5
34.9
50
68
A02BC03
ATC
lansoprazole; oral
1.9
33.6
612
3830
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
32.0
709
4699
A02BC01
ATC
omeprazole; systemic
1.9
32.0
567
3507
A02BA02
ATC
ranitidine; systemic
2.0
31.7
425
2394
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
+∞
31.3
30
*
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
36.2
30.6
39
11
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.3
30.6
52
85
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
6.3
30.6
52
85
K82.3
ICD-10 Finland
Fistula of gallbladder
+∞
30.3
29
*
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.1
29.4
127
427
TJK01
NOMESCO Finland
Laparoscopic cholangiography
+∞
29.2
28
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
8.5
27.9
36
43
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
27.9
952
7052
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
27.5
413
2405
J01MA02
ATC
ciprofloxacin; systemic
1.7
27.3
765
5364
K80.4
ICD-10 Finland
Calculus of bile duct with cholecystitis
274.8
26.8
27
*
ZXE00
NOMESCO Finland
One hour or less
1.7
26.6
734
5115
D02
ICPC
Abdominal pain epigastric
2.8
26.4
138
516
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
26.1
427
2552
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
26.0
444
2690
N03AX16
ATC
[U] pregabalin
1.8
25.9
459
2812
P01AB01
ATC
metronidazole; oral, rectal
1.7
25.6
747
5268
D01
ICPC
Abdominal pain/cramps general
2.1
24.8
245
1225
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
24.8
215
1020
JAH01
NOMESCO Finland
Laparoscopy
3.2
22.7
92
298
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
7.4
22.1
32
44
K85.8
ICD-10 Finland
Other acute pancreatitis
+∞
21.9
21
*
D13.5
ICD-10 Finland
Benign neoplasm: Extrahepatic bile ducts
+∞
21.9
21
*
A03FA02
ATC
cisapride; oral, rectal
2.3
21.8
171
776
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
4.2
21.5
57
138
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
21.2
220
1117
R10.0
ICD-10 Finland
Acute abdomen
3.5
21.1
73
214
K80
ICD-10 Finland
Cholelithiasis
16.8
21.0
33
20
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
6.0
20.9
37
63
UJK12
NOMESCO Finland
Peroral cholangioscopy
+∞
20.9
20
*
J01DB01
ATC
cefalexin; oral
1.7
20.7
1493
12920
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.0
20.7
94
325
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
212.2
20.6
21
*
K86.2
ICD-10 Finland
Cyst of pancreas
111.3
20.6
22
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
20.5
707
5128
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
20.3
205
1030
K82.1
ICD-10 Finland
Hydrops of gallbladder
+∞
19.8
19
*
J01MA12
ATC
levofloxacin; systemic
1.8
19.6
349
2121
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
106.2
19.6
21
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
19.0
123
512
D06
ICPC
Abdominal pain localized other
2.2
18.9
176
856
A03CA02
ATC
clidinium and psycholeptics; oral
2.4
18.8
134
583
R52.9
ICD-10 Finland
Pain, unspecified
2.0
18.5
206
1072
M54.5
ICD-10 Finland
Low back pain
1.6
18.4
661
4811
M79.6
ICD-10 Finland
Pain in limb
1.5
18.2
808
6163
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
17.9
89
324
WX704
NOMESCO Finland
Intubation
2.2
17.6
155
737
TJK00
NOMESCO Finland
Intraoperative cholangiography
181.6
17.5
18
*
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
181.6
17.5
18
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
17.5
325
1996
WX002
NOMESCO Finland
Sedation and analgesia
1.7
17.4
374
2391
N02BE01
ATC
paracetamol; systemic, rectal
1.8
17.1
1657
14992
A02BC04
ATC
rabeprazole; oral
2.1
16.9
173
873
M03BX02
ATC
tizanidine; oral
1.5
16.9
1058
8631
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
4.3
16.7
43
102
57401
ICD-8 Finland
Cholelithiasis, Cum cholecystitide chronica
+∞
16.7
16
*
57408
ICD-8 Finland
Cholelithiasis, Alia definita
+∞
16.7
16
*
K85.1
ICD-10 Finland
Biliary acute pancreatitis
+∞
16.7
16
*
K29.7
ICD-10 Finland
Gastritis, unspecified
2.9
16.6
78
275
ZXD05
NOMESCO Finland
Urgent procedure
1.6
16.6
528
3716
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
171.5
16.5
17
*
H02AB06
ATC
prednisolone; systemic
1.5
16.5
873
6866
D98
ICPC
Cholecystitis/cholelithiasis
23.3
16.4
23
10
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
4.0
16.3
46
117
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
16.3
249
1440
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
16.2
200
1078
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
16.1
1190
9997
R96
ICPC
Asthma
1.9
16.0
202
1097
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
15.8
361
2339
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
15.8
417
2805
C10AC01
ATC
colestyramine; oral
3.4
15.7
56
168
J02AC01
ATC
fluconazole; systemic
1.5
15.5
680
5121
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
15.5
329
2091
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
15.4
105
448
R03AC02
ATC
salbutamol; inhalant
1.5
15.2
970
7869
Z3231
NOMESCO Finland
Registered nurse
1.6
15.2
492
3466
Z3226
NOMESCO Finland
Physiotherapist
1.7
15.2
341
2198
J45
ICD-10 Finland
Asthma
1.9
15.2
198
1088
C03CA01
ATC
furosemide; systemic
1.5
15.0
637
4760
Z2221
NOMESCO Finland
Medical doctor
1.6
14.9
490
3462
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
14.9
499
3542
R06.0
ICD-10 Finland
Dyspnoea
1.5
14.6
519
3728
5754A
ICD-9 Finland
Other disorders of gallbladder, Perforation of gallbladder
+∞
14.6
14
*
K82
ICD-10 Finland
Other diseases of gallbladder
+∞
14.6
14
*
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
80.7
14.6
16
*
R53
ICD-10 Finland
Malaise and fatigue
1.6
14.5
477
3368
A02BA04
ATC
nizatidine; systemic
2.0
14.5
156
802
U07
ICPC
Urine symptom/complaint other
1.9
14.4
183
996
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.0
14.4
65
225
A41.9
ICD-10 Finland
Sepsis, unspecified
2.7
14.4
78
298
H02AB04
ATC
methylprednisolone; systemic
1.7
14.3
265
1621
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
14.2
232
1366
N03AX12
ATC
[U] gabapentin; oral
1.7
14.2
297
1876
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
14.2
303
1926
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
42.8
14.1
17
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
13.8
1220
10455
R4110
NOMESCO Finland
Physiotherapy
1.5
13.7
512
3709
A03DA02
ATC
pitofenone and analgesics; systemic
3.5
13.6
47
138
M48.0
ICD-10 Finland
Spinal stenosis
1.7
13.6
253
1547
K86.1
ICD-10 Finland
Other chronic pancreatitis
75.7
13.6
15
*
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
141.0
13.5
14
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
13.4
348
2321
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
13.3
249
1525
R11
ICD-10 Finland
Nausea and vomiting
1.9
13.3
162
870
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
13.2
690
5340
M25.5
ICD-10 Finland
Pain in joint
1.5
13.2
565
4205
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
13.2
273
1719
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
13.1
518
3792
M01AH02
ATC
rofecoxib; oral
1.7
13.1
243
1484
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
13.1
766
6055
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.6
13.1
329
2177
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.2
13.0
52
168
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
12.9
391
2702
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
12.9
190
1085
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
12.8
293
1892
K76.9
ICD-10 Finland
Liver disease, unspecified
4.2
12.7
33
79
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.5
12.7
79
323
127
Kela drug reimbursment
Transplant complication
4.4
12.6
31
71
R01AD09
ATC
mometasone; nasal
1.4
12.5
745
5892
K81.1
ICD-10 Finland
Chronic cholecystitis
+∞
12.5
12
*
R13
ICD-10 Finland
Dysphagia
2.0
12.5
144
758
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
12.5
239
1472
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
12.4
647
4994
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.8
12.3
61
222
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
12.3
130
664
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.6
12.1
69
270
J01FA10
ATC
azithromycin; systemic
1.4
12.1
927
7655
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
12.1
190
1106
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
3.8
12.0
36
96
R02
ICPC
Shortness of breath/dyspnoea
1.7
12.0
259
1646
R07.3
ICD-10 Finland
Other chest pain
1.8
11.9
195
1148
C07AB07
ATC
bisoprolol; oral
1.4
11.9
923
7632
J01DA01
ATC
[U] cefalexin
1.4
11.7
1081
9196
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
11.7
353
2431
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
11.7
863
7069
M01AH05
ATC
etoricoxib; oral
1.4
11.6
1052
8916
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.1
11.6
117
587
M01AH01
ATC
celecoxib; oral
1.6
11.6
326
2210
R51.80
ICD-10 Finland
Headache
1.6
11.6
263
1694
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
11.5
289
1908
57500
ICD-8 Finland
Cholecystitis and cholangitis, without mention of calculus, Cholecystitis acuta
+∞
11.5
11
*
5741A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder with other cholecystitis[CHOLECYSTOLITHIASIS CUM CHOLECYSTITIDE CHR,SINE OBS]
+∞
11.5
11
*
5740A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder with acute cholecystitis[CHOLECYSTOLITHIASIS CUM CHOLECYSTITIDE AC,SINE OBST]
+∞
11.5
11
*
N06AX21
ATC
duloxetine; oral
1.7
11.4
204
1231
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
11.4
452
3296
B01AB05
ATC
enoxaparin; parenteral
1.4
11.4
566
4314
L17
ICPC
Foot/toe symptom/complaint
1.5
11.4
545
4126
G44.2
ICD-10 Finland
Tension-type headache
1.7
11.3
232
1455
J01FA09
ATC
clarithromycin; systemic
1.5
11.3
512
3835
UJD02
NOMESCO Finland
Gastroscopy
2.2
11.3
96
451
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.1
11.2
47
156
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
4.9
11.2
24
49
L04AX01
ATC
azathioprine; systemic
2.4
11.2
74
312
1413
FHL
Laparoscopy and other therapeutic procedure
3.1
11.1
46
152
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
11.0
392
2798
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
10.9
202
1231
L04AA06
ATC
mycophenolic acid; systemic
3.6
10.9
35
98
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
43.6
10.9
13
*
R03DC03
ATC
montelukast; oral
1.6
10.9
274
1807
JN1AE, ,
SPAT
2.6
10.9
62
243
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.7
10.8
202
1234
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
10.8
69
286
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
10.8
367
2590
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
10.8
311
2117
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
2.6
10.7
61
239
R12
ICD-10 Finland
Heartburn
1.9
10.7
148
827
ZXA05
NOMESCO Finland
Left side
1.5
10.7
448
3298
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.2
10.6
88
409
A02BA03
ATC
famotidine; systemic
2.3
10.6
77
339
C01DA14
ATC
isosorbide mononitrate; oral
1.5
10.6
319
2194
N02BF01
ATC
gabapentin; oral
1.7
10.6
190
1149
R01AD08
ATC
fluticasone; nasal
1.5
10.5
456
3378
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.2
10.5
92
437
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
+∞
10.4
10
*
5770A
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA NONALCOHOLICA NONHAEMORRHAGICA]
+∞
10.4
10
*
57609
ICD-8 Finland
Other diseases of gallbladder and biliary, Alii definiti sive NUD
+∞
10.4
10
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
10.4
141
784
A06AD11
ATC
lactulose; oral
1.6
10.4
293
1985
A46
ICD-10 Finland
Erysipelas
1.6
10.4
265
1754
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
10.4
252
1648
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
10.3
418
3054
M54.3
ICD-10 Finland
Sciatica
2.0
10.3
111
570
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.6
10.3
58
226
M02AA07
ATC
piroxicam; topical
1.4
10.3
653
5178
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
10.3
209
1307
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
4.7
10.2
23
49
N05BA01
ATC
diazepam; systemic, rectal
1.6
10.2
232
1491
S29
ICPC
Skin symptom/complaint other
1.5
10.2
361
2567
J01FA06
ATC
roxithromycin; oral
1.4
10.1
689
5524
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
10.1
456
3400
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
10.0
186
1134
H01
ICPC
Ear pain/earache
1.7
10.0
190
1167
M01AX17
ATC
nimesulide; oral
1.5
10.0
426
3144
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
10.0
438
3250
R05
ICD-10 Finland
Cough
1.5
9.9
371
2669
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.8
432
3204
L03
ICPC
Low back symptom/complaint
1.4
9.8
495
3768
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
9.8
107
554
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
9.7
151
875
A07EA06
ATC
budesonide; oral, local oral
2.4
9.7
67
288
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.0
9.7
104
534
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
9.7
432
3213
R03AC03
ATC
terbutaline; inhalant
1.6
9.6
235
1537
A01
ICPC
Pain general/multiple sites
1.7
9.6
190
1178
A03CA05
ATC
glycopyrronium bromide and psycholeptics; systemic
3.8
9.6
29
78
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
9.6
149
864
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.0
9.6
20
40
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
4.6
9.5
22
48
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
9.5
205
1300
E66.01
ICD-10 Finland
Obesity due to excess calories
1.8
9.5
134
754
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.4
9.5
61
254
JAH00
NOMESCO Finland
Laparotomy
2.6
9.5
55
218
ZXA10
NOMESCO Finland
Bilateral
1.5
9.5
331
2345
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
9.5
805
6671
UKC02
NOMESCO Finland
Cystoscopy
1.5
9.4
279
1908
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
100.5
9.4
10
*
K83.4
ICD-10 Finland
Spasm of sphincter of Oddi
+∞
9.4
9
*
57709
ICD-8 Finland
Diseases of pancreas, Pancreatitis NUD
+∞
9.4
9
*
J01EA01
ATC
trimethoprim; systemic
1.4
9.4
482
3675
A11
ICPC
Chest pain NOS
1.7
9.4
167
1007
C08CA05
ATC
nifedipine; systemic
1.9
9.4
115
619
R03BA02
ATC
budesonide; inhalant
1.5
9.4
306
2138
G47.3
ICD-10 Finland
Sleep apnoea
1.5
9.3
351
2524
R01AD58
ATC
fluticasone, combinations; nasal
1.5
9.3
366
2654
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.4
9.2
64
276
R21
ICPC
Throat symptom/complaint
1.5
9.2
296
2059
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
9.2
208
1336
E0000UV, ,
ATC
1.4
9.1
702
5718
ZXD20
NOMESCO Finland
Day surgery
1.6
9.1
212
1371
K76.80
ICD-10 Finland
Hepatic cyst
4.4
9.1
22
50
K92.1
ICD-10 Finland
Melaena
2.0
9.1
103
540
X58
ICD-10 Finland
Exposure to other specified factors
1.6
9.1
233
1543
R06AE07
ATC
cetirizine; oral
1.4
9.0
716
5855
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
9.0
475
3632
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
7.1
9.0
21
30
WVA20
NOMESCO Finland
Medicine administration
2.6
9.0
51
200
J01CA04
ATC
amoxicillin; systemic
1.4
9.0
1400
12694
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
8.9
111
600
Y0599
ICD-8 Finland
Investigation of digestive system
3.0
8.9
38
128
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
12.6
8.9
15
12
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.9
242
1625
R60.0
ICD-10 Finland
Localized oedema
1.6
8.9
232
1543
J01MA01
ATC
ofloxacin; systemic
1.7
8.8
147
870
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.4
8.8
59
251
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
8.8
187
1182
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
8.7
236
1580
K11.2
ICD-10 Finland
Sialoadenitis
2.4
8.7
59
252
I20.09
ICD-10 Finland
Unstable angina
1.9
8.7
110
598
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
50.2
8.7
10
*
M79.1
ICD-10 Finland
Myalgia
1.5
8.6
246
1669
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.1
8.6
35
115
J01AA02
ATC
doxycycline; systemic
1.4
8.6
1382
12537
A03
ICPC
Fever
1.5
8.5
243
1646
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.5
1167
10321
S06.0
ICD-10 Finland
Concussion
1.6
8.5
180
1137
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.5
305
2172
R31
ICD-10 Finland
Unspecified haematuria
1.7
8.4
176
1107
XKD03
NOMESCO Finland
Urethral pressure profilometry
2.6
8.4
49
195
JKB00
NOMESCO Finland
Incision of bile duct
90.5
8.4
9
*
R07.0
ICD-10 Finland
Pain in throat
1.9
8.4
105
569
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.2
8.4
68
314
57708
ICD-8 Finland
Diseases of pancreas, Pancreatitis acuta alia
+∞
8.3
8
*
57608
ICD-8 Finland
Other diseases of gallbladder and biliary, Dyskinesia viarum biliferarum
+∞
8.3
8
*
J46
ICD-10 Finland
Status asthmaticus
2.4
8.3
57
245
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
8.3
124
711
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.8
8.2
131
765
J20
ICD-10 Finland
Acute bronchitis
1.6
8.2
175
1106
K59.1
ICD-10 Finland
Functional diarrhoea
1.9
8.2
100
537
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
1.9
8.2
97
516
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
8.2
392
2942
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.5
8.2
48
192
R05
ICPC
Cough
1.4
8.2
418
3175
JFB00
NOMESCO Finland
Partial resection of small intestine
3.1
8.1
33
108
K02.1
ICD-10 Finland
Caries of dentine
1.3
8.1
918
7871
N02AA05
ATC
oxycodone; systemic
1.4
8.1
343
2517
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
8.0
152
932
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.9
8.0
36
125
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.8
8.0
38
136
SPAT1263
SPAT
Sampling
1.3
8.0
679
5584
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.0
649
5302
S18
ICPC
Laceration/cut
1.3
8.0
804
6776
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
8.0
375
2805
J01DA06
ATC
[U] cefuroxime
1.5
8.0
233
1587
AA1AD
NOMESCO Finland
CT of head and brain
1.4
8.0
530
4202
M01AB05
ATC
diclofenac; systemic, rectal
1.3
7.9
1102
9715
U02
ICPC
Urinary frequency/urgency
1.5
7.9
272
1918
L28
ICPC
Limited function/disability (L)
1.4
7.9
362
2697
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.9
414
3158
R03BA05
ATC
fluticasone; inhalant
1.5
7.9
290
2073
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
7.9
424
3248
D09
ICPC
Nausea
2.1
7.8
73
357
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
45.2
7.7
9
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.8
7.7
119
690
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.6
7.7
188
1230
A07AA02
ATC
nystatin; oral
1.8
7.7
106
594
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
18.4
7.6
11
6
D11
ICPC
Diarrhoea
1.6
7.6
181
1177
K66.0
ICD-10 Finland
Peritoneal adhesions
8.1
7.6
16
20
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.6
7.6
157
986
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
25.1
7.6
10
*
H02AB07
ATC
prednisone; oral
1.5
7.5
234
1617
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.5
685
5683
R74
ICPC
Upper respiratory infection acute
1.4
7.5
460
3597
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.5
7.5
225
1543
L04AD02
ATC
tacrolimus; systemic
4.4
7.4
18
41
A02BX02
ATC
sucralfate; oral
2.1
7.4
71
352
5745A
ICD-9 Finland
Cholelithiasis, Calculus of bile duct without mention of cholecystitis[CHOLEDOCHOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
+∞
7.3
7
*
5750A
ICD-9 Finland
Other disorders of gallbladder, Acute cholecystitis
+∞
7.3
7
*
K81.8
ICD-10 Finland
Other cholecystitis
+∞
7.3
7
*
JL5CM
NOMESCO Finland
Bile and pancreas ducts extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
JK1AT
NOMESCO Finland
Cathetrisation of bile cyst with radiological guidance
+∞
7.3
7
*
N06AX11
ATC
mirtazapine; oral
1.3
7.3
573
4648
Z71.8
ICD-10 Finland
Other specified counselling
1.3
7.3
543
4370
N06AA09
ATC
amitriptyline; systemic
1.6
7.3
167
1077
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.2
576
4680
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
7.2
182
1199
J01DA09
ATC
[U] cefadroxil
1.4
7.2
418
3234
K59.09
ICD-10 Finland
Constipation, unspecified
1.7
7.2
123
734
L05
ICPC
Flank/axilla symptom/complaint
1.7
7.2
116
681
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
2.5
7.2
42
168
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.7
7.2
125
750
L13
ICPC
Hip symptom/complaint
1.4
7.2
356
2685
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
7.2
388
2970
N05CF01
ATC
zopiclone; oral
1.3
7.1
563
4565
205
Kela drug reimbursment
Chronic hypertension
1.3
7.1
488
3876
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
7.1
164
1058
K51.5
ICD-10 Finland
Left sided colitis
2.5
7.1
43
175
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
7.1
142
884
M01AB55
ATC
diclofenac, combinations; oral
1.7
7.1
123
737
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
3.8
7.1
21
56
C05AA08
ATC
fluocortolone; rectal, topical
1.5
7.1
222
1536
M54
ICD-10 Finland
Dorsalgia
1.5
7.0
192
1288
ZXA00
NOMESCO Finland
Right side
1.4
7.0
459
3622
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.0
7.0
68
339
C03DA01
ATC
spironolactone; oral
1.5
6.9
217
1499
A02BDXX, ,
ATC
2.0
6.9
68
340
XKC03
NOMESCO Finland
Water cystometry
2.2
6.9
58
273
N02AC04
ATC
dextropropoxyphene; oral
2.0
6.9
72
368
AN1
HP
Coronary angiography
1.5
6.9
187
1254
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.7
6.9
115
683
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
3.5
6.8
23
67
KH1AD
NOMESCO Finland
CT of urinary organs
2.2
6.8
54
248
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.8
316
2355
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.8
480
3827
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
6.8
387
2985
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
40.2
6.8
8
*
WX290
NOMESCO Finland
Other blockage of nerve
1.3
6.7
676
5660
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.0
6.7
74
386
SPAT1325
SPAT
Vaccination
1.3
6.7
563
4603
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
6.6
122
743
E66.8
ICD-10 Finland
Other obesity
2.0
6.6
73
380
T81.9
ICD-10 Finland
Unspecified complication of procedure
2.7
6.6
33
122
SFA10
NOMESCO Finland
One-surface restoration
1.3
6.6
857
7413
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.6
863
7472
WX004
NOMESCO Finland
Patient-controlled sedation
12.3
6.6
11
9
A02BD02
ATC
lansoprazole, tetracycline and metronidazole; systemic
2.4
6.6
43
182
R03BA01
ATC
beclometasone; inhalant
1.5
6.5
226
1595
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.5
450
3574
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
6.5
137
866
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.7
6.5
117
710
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
6.5
586
4834
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.7
6.5
115
695
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.0
6.5
67
342
Z94.0
ICD-10 Finland
Kidney transplant status
3.9
6.4
18
46
S54
ICPC
Skin, Repair/fix-suture/cast/prosth device
2.1
6.4
58
281
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
70.1
6.4
7
*
M19.9
ICD-10 Finland
Arthrosis, unspecified
1.9
6.4
75
399
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
6.4
293
2176
Z94.4
ICD-10 Finland
Liver transplant status
14.4
6.4
10
7
WZC30
NOMESCO Finland
Teaching
1.4
6.4
260
1891
J01FF01
ATC
clindamycin; systemic
1.3
6.4
422
3328
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.2
6.3
13
16
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
6.3
330
2507
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
6.3
325
2463
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
2.4
6.3
40
167
K29.1
ICD-10 Finland
Other acute gastritis
3.2
6.3
24
76
A28
ICPC
Limited function/disability NOS
1.4
6.3
345
2641
XKD00
NOMESCO Finland
Uroflowmetry
1.5
6.3
225
1597
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
6.3
280
2070
R5140
NOMESCO Finland
Monitoring the use of the aid
1.5
6.3
171
1147
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
6.3
318
2404
57501
ICD-8 Finland
Cholecystitis and cholangitis, without mention of calculus, Cholecystitis chronica
+∞
6.3
6
*
JK3MB
NOMESCO Finland
Postoperative cholangiography
+∞
6.3
6
*
K83.2
ICD-10 Finland
Perforation of bile duct
+∞
6.3
6
*
I25
ICD-10 Finland
Chronic ischaemic heart disease
1.8
6.2
84
468
JJC00
NOMESCO Finland
Allogenic transplantation of liver
26.8
6.2
8
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.2
713
6057
N02BF02
ATC
pregabalin; oral
1.7
6.2
107
641
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.1
6.2
25
82
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
6.2
113
688
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.5
6.2
195
1350
L01BB02
ATC
mercaptopurine; oral
3.5
6.2
20
57
SPAT1336
SPAT
Request for examination
2.0
6.2
66
341
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
6.2
186
1276
JAD10
NOMESCO Finland
Repair of incisional hernia
5.4
6.2
17
32
C08CA01
ATC
amlodipine; oral
1.3
6.2
693
5873
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.6
6.1
33
127
SPAT1153
SPAT
Removal of sutures
1.3
6.1
510
4152
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.1
669
5647
A07DA03
ATC
loperamide; oral
2.1
6.1
57
280
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.5
6.1
169
1138
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
6.1
107
645
SPAT1254
SPAT
Administration of medicine
1.4
6.1
247
1796
EB1AA, ,
SPAT
1.7
6.1
103
615
M01AE02
ATC
naproxen; oral, rectal
1.3
6.1
907
7955
N05BA04
ATC
oxazepam; oral
1.3
6.1
442
3533
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.0
413
3272
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.0
708
6030
EBA00
NOMESCO Finland
Extraction of tooth
1.3
6.0
549
4526

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
469
1559
3.67
117.35
3.6
2.3
8.58
6.80
umol/l
1.05
429
1367
1329
8423
2.94
100.41
8.6
6.0
11.95
11.12
umol/l
1.77
1296
8004
902
4714
2.74
99.34
3.8
2.2
62.77
57.06
u/l
0.84
852
4327
389
1410
3.21
82.28
3.2
1.8
43.04
33.14
u/l
0.44
341
1172
717
4107
2.20
56.07
6.0
3.7
88.17
88.65
%
0.19
702
4013
822
5024
2.12
53.86
4.3
3.0
35.38
32.62
u/l
0.61
788
4739
425
2032
2.41
50.33
1.4
1.3
—
—
—
0
0
1553
12377
2.42
47.92
11.9
7.7
86.10
77.42
u/l
5.51
1508
11657
165
551
3.19
38.78
3.9
3.1
98.26
2622.88
u/ml
0.78
139
472
368
1845
2.23
37.96
2.4
2.2
150.96
127.01
ug/g
0.57
299
1458
414
2178
2.15
37.84
1.3
1.2
—
—
—
0
0
316
1489
2.35
37.75
2.8
1.9
0.21
0.21
g/l
0.33
300
1368
1053
7608
1.87
37.73
6.6
4.6
35.17
35.46
g/l
0.93
994
7104
1054
7687
1.84
35.92
19.2
16.2
1.27
1.29
inr
0.55
892
6362
123
378
3.41
33.01
1.4
1.3
310.79
305.54
ug/g
0.08
73
217
1225
9617
1.78
30.01
6.7
4.7
6.82
6.69
mmol/l
1.23
1178
9110
1184
9233
1.75
29.39
10.3
9.4
4.43
4.10
e9/l
2.94
1019
7962
698
4702
1.77
29.19
5.6
4.0
—
—
—
0
0
1106
8478
1.73
29.02
7.4
6.2
0.20
0.19
e9/l
1.56
956
7309
74
177
4.31
28.37
1.6
1.5
0.74
0.84
g/l
0.47
62
149
1073
8194
1.71
28.19
7.2
6.1
0.60
0.59
e9/l
0.89
907
6932
1003
7521
1.71
28.18
7.7
6.3
0.69
0.68
%
0.14
938
7003
1089
8360
1.71
27.96
7.3
6.1
1.95
1.87
e9/l
0.57
946
7267
1074
8215
1.71
27.94
7.2
6.1
0.04
0.04
e9/l
0.54
912
6953
1000
7537
1.69
27.18
7.7
6.3
8.69
8.97
%
2.49
935
7022
999
7539
1.69
26.92
7.4
6.2
57.67
57.79
%
0.11
950
7158
690
4717
1.73
26.86
4.3
3.2
0.45
0.47
e6/l
0.09
526
3455
997
7524
1.69
26.83
7.5
6.2
2.84
2.82
%
0.09
931
7015
1013
7683
1.69
26.70
7.6
6.2
27.49
27.06
%
0.59
954
7252
849
6157
1.69
26.44
5.3
4.0
101.31
105.67
e6/l
0.06
628
4316
1115
8694
1.69
26.27
9.3
6.9
1.21
1.22
mmol/l
0.63
987
7460
315
1700
2.02
26.03
4.0
4.3
9.56
21.15
ug/l
1.05
251
1389
1234
9911
1.70
25.75
4.8
3.0
58.79
44.21
u/l
4.49
1169
9193
765
5426
1.69
25.70
4.4
3.3
150.56
86.94
e6/l
0.34
603
4133
322
1780
1.97
24.77
1.5
1.3
—
—
—
0
0
230
1125
2.19
24.56
2.8
2.9
10.69
10.75
g/l
0.05
217
1026
464
2895
1.80
24.44
2.8
2.6
12.47
12.60
umol/l
0.14
434
2696
500
3190
1.77
24.41
3.5
2.8
511.80
523.00
mosm/kgh2o
0.57
454
2776
409
2461
1.84
24.25
2.8
2.6
21.25
21.88
%
0.44
388
2286
91
281
3.35
24.22
3.3
3.2
289.37
1452.13
u/ml
0.66
82
259
1308
10766
1.70
23.92
6.7
5.0
106.88
3262.06
e6/l
3.83
26
142
1017
7856
1.64
23.84
8.5
6.2
1.21
1.21
mmol/l
1.18
955
7180
435
2685
1.81
23.66
2.8
2.5
2.38
2.30
g/l
2.22
412
2481
1094
8623
1.64
23.50
5.3
4.1
0.01
0.19
estimate
0.47
224
1675
1084
8550
1.63
23.00
5.2
4.1
5.56
1.79
estimate
0.29
241
1769
972
7470
1.62
22.90
3.3
2.7
—
—
estimate
—
0
0
1072
8440
1.62
22.84
5.2
4.1
0.00
0.00
estimate
0.50
230
1709
966
7432
1.61
22.50
3.6
3.0
126.05
123.95
ug/l
0.07
913
6847
1409
11914
1.71
22.42
5.6
4.4
13.36
13.05
mm/h
0.32
1324
11083
107
383
2.90
22.17
1.4
1.1
127.50
79.74
titre
0.45
12
38
463
2966
1.74
21.95
1.5
1.5
2.42
2.46
g/l
0.16
275
1734
559
3775
1.68
21.81
3.4
2.6
5.28
5.90
e6/l
0.65
517
3422
106
384
2.86
21.49
1.5
1.1
523.33
588.33
titre
—
6
12
269
1475
1.96
20.96
9.5
8.1
—
—
—
0
0
759
5587
1.60
20.72
7.4
5.9
—
—
—
0
0
186
894
2.20
20.64
1.9
1.9
1.55
1.52
g/l
0.05
177
814
845
6387
1.58
20.55
4.9
3.9
35.57
66.22
ng/l
1.30
623
4693
205
1026
2.12
20.53
1.3
1.3
—
—
—
0
0
728
5334
1.59
20.10
5.0
4.0
7.40
7.40
ph
0.12
501
3830
910
7072
1.55
19.11
14.6
11.2
0.00
0.00
e9/l
0.61
719
5728
716
5285
1.57
18.83
2.9
2.3
—
—
—
0
0
879
6800
1.55
18.70
4.6
3.6
6.28
6.28
ph
0.01
488
3700
489
3308
1.64
18.44
4.5
3.9
226.41
343.05
ng/l
0.67
387
2699
685
5030
1.57
18.30
7.0
6.2
—
—
—
0
0
416
2704
1.69
18.28
3.8
3.1
2.69
2.55
e6/l
0.10
201
1329
502
3436
1.63
17.99
1.3
1.3
0.92
1.40
u/ml
1.28
129
882
508
3513
1.61
17.36
2.2
1.7
1.14
1.33
mg/l
0.91
406
2715
633
4610
1.56
17.31
2.8
2.3
2.80
2.86
mg/l
0.25
551
3927
426
2827
1.65
17.16
3.6
3.1
0.81
0.82
mmol/l
2.25
403
2639
269
1570
1.83
17.13
8.6
6.9
1.30
1.36
mmol/l
0.42
264
1542
1689
15378
1.91
17.05
25.9
16.1
24.78
24.74
mg/l
0.02
1502
12649
439
2956
1.63
16.63
3.7
3.0
1.22
1.21
e6/l
0.01
222
1595
724
5478
1.52
16.41
4.1
3.4
—
—
—
0
0
282
1706
1.77
15.86
4.3
3.4
7.38
7.38
ph
0.12
149
969
571
4137
1.54
15.66
3.2
2.7
344.91
341.95
umol/l
0.27
500
3586
331
2114
1.69
15.28
1.5
1.3
390.12
505.14
titre
0.93
81
479
278
1696
1.75
15.15
4.4
3.4
5.84
5.85
kpa
0.02
273
1652
557
4039
1.54
15.12
2.9
2.3
—
—
—
0
0
154
780
2.06
14.86
1.4
1.2
—
—
—
0
0
271
1653
1.75
14.75
4.3
3.4
1.89
1.88
mmol/l
0.02
244
1421
958
7784
1.47
14.73
2.4
2.2
97.42
96.98
pmol/l
0.10
519
3890
344
2240
1.65
14.69
7.2
5.2
1.03
1.03
mmol/l
0.01
312
2057
318
2029
1.68
14.69
8.7
7.0
7.41
7.42
ph
0.57
158
1105
286
1784
1.71
14.35
9.2
7.3
95.38
95.45
%
0.06
278
1721
602
4480
1.50
14.31
3.7
3.1
0.18
0.03
0.36
11
124
317
2034
1.67
14.31
8.7
6.9
12.09
12.24
kpa
0.23
306
1951
317
2034
1.67
14.31
8.7
6.9
5.08
5.12
kpa
0.23
306
1949
377
2533
1.61
14.15
2.3
2.0
29.70
29.46
s
0.45
368
2462
548
4015
1.51
13.98
4.9
4.0
0.14
0.13
—
7
46
313
2014
1.66
13.95
8.7
6.9
0.79
0.96
mmol/l
0.34
264
1657
349
2314
1.62
13.80
2.4
2.0
—
—
—
0
0
244
1474
1.75
13.70
1.6
1.5
—
—
—
0
0
184
1031
1.87
13.23
3.8
2.9
127.88
127.72
g/l
0.03
178
1003
239
1464
1.72
12.74
9.7
6.7
9.65
10.49
mmol/l
1.07
226
1404
40
111
3.66
12.61
1.4
1.1
170.00
84.00
titre
—
5
15
811
6515
1.43
12.52
2.5
2.2
—
—
—
0
0
102
473
2.22
12.35
3.0
3.4
1.48
2.04
index
0.56
56
229
164
908
1.88
12.24
3.2
2.5
1.15
1.15
%
0.05
164
900
1417
12633
1.48
12.11
30.2
20.3
13.85
13.73
%
2.92
1411
12447
281
1826
1.63
11.94
1.7
1.6
—
—
—
0
0
785
6315
1.42
11.81
5.2
4.1
0.57
0.39
estimate
0.11
187
1405
183
1062
1.80
11.74
10.9
8.7
24.32
24.39
mmol/l
0.11
178
1035
161
901
1.86
11.62
3.2
2.5
0.65
0.62
%
0.65
161
895
1704
15893
1.72
11.33
29.6
19.5
139.66
139.64
mmol/l
0.11
1682
15560
104
505
2.12
11.24
1.7
1.6
—
—
—
0
0
1706
15926
1.72
11.18
29.9
19.7
3.96
3.98
mmol/l
2.02
1683
15563
106
521
2.10
11.11
1.7
1.6
18.11
17.84
u/ml
0.01
24
101
1377
12283
1.44
11.08
5.0
4.5
15.01
14.91
pmol/l
0.71
1280
11169
83
376
2.26
10.66
1.3
1.2
—
—
—
0
0
691
5511
1.40
10.61
3.5
3.2
1339.20
1505.52
ng/l
0.60
604
4767
608
4747
1.41
10.55
5.6
4.3
0.00
0.00
estimate
0.01
217
1577
65
269
2.47
10.24
1.5
1.3
—
—
—
0
0
755
6138
1.38
10.24
3.6
3.5
2.36
2.36
mmol/l
0.42
675
5556
279
1875
1.57
10.22
2.0
1.7
—
—
—
0
0
30
79
3.84
10.22
1.2
1.0
—
—
—
0
0
61
246
2.53
10.15
1.3
1.2
280.40
277.42
u/ml
0.03
43
138
36
108
3.38
10.15
1.3
1.3
—
—
—
0
0
198
1228
1.68
10.03
1.2
1.2
—
—
—
0
0
60
242
2.53
9.98
1.5
1.4
166.87
156.85
au/ml
0.28
15
70
52
196
2.70
9.91
1.1
1.1
—
—
—
0
0
166
987
1.75
9.80
3.9
3.5
24.10
24.26
mmol/l
0.28
166
976
911
7670
1.36
9.77
2.9
2.4
78.00
79.22
nmol/l
0.66
835
6819
684
5511
1.38
9.65
4.5
4.0
6.56
8.34
mg/mmol
0.69
415
3321
698
5645
1.37
9.61
3.7
3.3
7.17
7.11
mmol/l
0.13
585
4748
1570
14484
1.49
9.56
6.4
5.6
1.89
1.97
mu/l
1.98
1469
13280
666
5351
1.38
9.53
2.6
2.1
215.58
208.34
u/l
0.06
631
5059
35
108
3.28
9.46
1.3
1.3
0.30
0.41
g/l
1.48
27
85
35
108
3.28
9.46
1.3
1.3
5.95
6.86
g/l
0.92
27
84
35
108
3.28
9.46
1.3
1.3
2.49
2.98
g/l
1.19
27
84
53
207
2.61
9.43
1.1
1.0
—
—
—
0
0
672
5423
1.37
9.30
3.8
3.4
37.82
46.23
mg/l
0.61
429
3368
34
105
3.28
9.18
1.8
1.2
—
—
—
0
0
556
4365
1.39
9.07
4.4
3.5
1.47
0.07
estimate
0.47
173
1340
395
2927
1.44
8.95
1.3
1.3
33.08
36.50
iu/ml
0.16
113
908
639
5160
1.36
8.67
1.9
1.7
21.11
20.65
nmol/l
0.33
566
4327
222
1472
1.58
8.58
1.5
1.5
—
—
—
0
0
276
1932
1.50
8.32
1.5
1.4
—
—
—
0
0
84
424
2.03
8.26
3.1
2.7
60.77
60.53
%
0.03
84
413
127
740
1.77
8.06
4.5
3.1
25.54
25.30
mmol/l
0.32
118
715
441
3398
1.39
7.89
5.7
4.7
—
—
—
0
0
147
899
1.69
7.85
2.5
2.4
—
—
—
0
0
198
1308
1.57
7.77
3.0
2.9
6.17
6.07
ph
0.68
127
893
288
2064
1.47
7.70
2.6
2.4
1.86
1.81
%
0.31
264
1819
157
987
1.64
7.55
3.0
3.5
4.45
4.46
pmol/l
0.06
145
873
221
1522
1.51
7.18
2.0
2.1
346.91
379.56
nmol/l
1.93
203
1401
477
3775
1.35
7.13
5.5
4.4
1.02
1.02
kg/l
0.02
344
2492
217
1497
1.51
6.99
2.5
2.8
66.19
66.29
g/l
0.08
202
1351
201
1365
1.53
6.97
4.8
4.2
0.73
0.72
%
0.01
74
402
1664
15739
1.47
6.93
21.3
14.6
—
—
—
0
0
1701
16161
1.52
6.92
17.9
12.0
28.00
24.42
u/l
7.32
1670
15634
202
1377
1.52
6.88
5.5
4.7
0.24
0.12
%
0.43
67
342
17
28
6.12
6.77
1.0
1.1
—
—
—
0
0
208
1432
1.51
6.76
5.1
4.3
1.26
0.94
%
0.57
79
424
210
1465
1.49
6.41
2.5
2.3
6.62
6.90
ug/l
0.09
173
1277
97
560
1.77
6.40
1.9
1.7
0.28
0.31
mg/l
0.21
35
265
158
1038
1.57
6.36
4.8
4.2
—
—
—
0
0
18
47
3.86
6.26
36.6
31.3
112.25
115.47
ug/l
0.07
12
40
356
2743
1.37
6.23
1.3
1.3
8.30
12.39
u/ml
0.63
131
1015
1366
12605
1.30
6.01
31.1
21.5
331.28
331.37
g/l
0.13
1358
12521
17
44
3.89
5.99
2.6
2.0
0.62
0.61
mmol/l
0.08
17
44
45
203
2.25
5.97
1.3
1.3
—
—
—
0
0
33
129
2.59
5.97
1.1
1.2
—
—
—
0
0
447
3591
1.32
5.89
1.9
1.7
56032606.49
25615196.30
pmol/l
0.34
373
2928
66
347
1.93
5.87
5.2
3.6
—
—
—
0
0
1713
16383
1.48
5.84
32.2
21.6
79.06
77.70
umol/l
0.81
1696
16160
195
1366
1.48
5.83
5.2
4.4
0.14
0.12
%
0.11
66
357
1560
14694
1.35
5.73
7.8
6.5
40.18
39.45
mmol/mol
2.48
1469
13615
1589
15018
1.36
5.64
6.0
5.3
6.08
5.94
mmol/l
3.83
1474
13651
144
956
1.55
5.56
1.4
1.3
239.45
154.30
u/ml
0.97
136
872
95
569
1.70
5.55
1.4
1.2
—
—
—
0
0
286
2166
1.38
5.54
1.8
1.7
—
—
—
0
0
221
1602
1.43
5.52
2.5
2.2
0.00
0.02
estimate
0.78
54
292
76
431
1.80
5.37
1.3
1.3
—
31.06
—
0
5
81
473
1.74
5.20
4.0
2.6
1.67
1.55
mg/l
0.58
75
427
96
589
1.66
5.15
2.4
1.9
22.12
21.34
s
0.24
82
532
15
31
4.87
5.12
1.0
1.0
—
—
—
0
0
386
3094
1.31
5.10
1.8
1.7
1102.88
1176.57
nmol/l
0.82
296
2300
108
692
1.59
4.89
2.4
1.8
10.29
1.53
ug/l
0.91
98
603
53
278
1.93
4.80
1.2
1.2
—
—
—
0
0
14
30
4.69
4.68
1.1
1.2
—
—
—
0
0
150
1044
1.47
4.66
6.9
5.9
24.05
24.57
mmol/l
1.05
145
999
195
1426
1.41
4.65
2.8
3.0
208.12
215.03
ng/l
0.10
178
1303
100
637
1.60
4.65
2.4
2.7
—
—
—
0
0
215
1605
1.38
4.55
2.6
2.5
75.92
68.86
e9/l
1.41
150
1166
449
3725
1.27
4.49
3.3
3.0
2.47
2.46
mmol/l
0.58
376
3362
143
998
1.47
4.40
1.3
1.4
—
—
—
0
0
259
2006
1.34
4.33
3.8
3.0
4.26
4.41
e9/l
0.26
227
1705
14
33
4.27
4.32
6.0
4.5
—
—
—
0
0
747
6598
1.22
4.15
2.1
1.9
1.37
1.32
mmol/l
0.94
645
5522
31
141
2.22
4.12
3.5
5.7
137.15
56.47
u/ml
—
6
45
119
816
1.49
4.02
1.9
1.7
1.34
1.51
g/l
1.31
104
717
181
1345
1.38
3.95
2.7
2.3
0.34
0.50
e6/l
0.75
175
1286
187
1402
1.37
3.87
4.2
3.8
92.60
90.64
ng/l
0.10
168
1206
107
725
1.50
3.84
1.3
1.2
—
—
—
0
0
51
286
1.80
3.83
4.3
3.2
3.60
4.36
e9/l
2.15
51
286
60
354
1.72
3.80
1.5
1.6
—
—
—
0
0
76
478
1.61
3.78
6.8
5.6
1.34
1.30
mmol/l
0.13
66
418
1720
16642
1.37
3.75
37.3
24.9
252.57
249.93
e9/l
0.89
1687
16268
119
829
1.46
3.73
4.5
3.6
1.02
1.02
ratio
0.44
103
749
1720
16645
1.36
3.72
37.2
24.9
91.28
91.48
fl
0.98
1704
16424
1720
16647
1.36
3.70
37.1
24.8
30.30
30.36
pg
0.68
1704
16425
1720
16647
1.36
3.70
38.2
25.4
39.84
39.82
%
0.05
1703
16417
1720
16647
1.36
3.70
37.3
24.9
4.43
4.42
e12/l
0.27
1679
16218
1720
16650
1.36
3.67
37.3
24.9
6.95
6.71
e9/l
3.85
1683
16223
1720
16651
1.36
3.66
37.5
25.1
133.00
133.27
g/l
0.33
1703
16437
70
439
1.62
3.54
1.3
1.1
—
—
—
0
0
50
288
1.76
3.47
1.4
1.6
—
—
—
0
0
36
187
1.94
3.44
1.3
1.3
—
—
nmol/l
—
0
0
23
100
2.32
3.43
1.2
1.2
55.29
36.81
mg/l
0.53
17
80
491
4236
1.21
3.33
5.6
5.8
2.22
4.04
ug/l
1.12
440
3780
62
384
1.64
3.31
4.4
3.2
7.72
7.93
kpa
0.46
62
377
13
38
3.44
3.31
2.2
1.9
—
—
—
0
0
53
316
1.70
3.27
5.6
3.6
2.89
2.72
mmol/l
0.16
38
226
55
332
1.68
3.25
4.5
3.1
87.88
89.39
%
0.60
55
324
164
1241
1.35
3.23
5.7
4.0
—
—
—
0
0
142
1051
1.38
3.22
4.7
3.9
5.12
5.19
kpa
0.55
131
1014
1508
14411
1.23
3.21
4.8
4.3
1.34
1.26
mmol/l
4.32
1397
13054
91
621
1.49
3.20
3.6
3.4
34.54
132.21
mg/l
0.60
78
537
15
55
2.74
3.15
2.0
2.0
—
—
—
0
0
34
179
1.92
3.15
3.0
3.4
10.64
11.62
index
0.39
22
90
91
624
1.48
3.13
3.6
3.4
30.77
44.46
mg/l
1.15
79
541
55
336
1.66
3.12
4.4
3.6
24.19
27.00
mg/l
0.24
43
233
49
291
1.70
3.09
1.2
1.3
27.43
26.27
u/l
0.04
43
247
6
8
7.52
3.05
1.3
2.5
—
—
—
0
0
35
189
1.87
3.02
1.1
1.2
—
—
—
0
0
20
87
2.31
3.01
1.8
1.6
—
—
—
0
0
138
1030
1.37
2.99
4.7
3.9
7.42
7.42
ph
0.02
114
863
60
382
1.59
2.91
5.9
4.6
—
—
—
0
0
65
422
1.56
2.90
1.8
2.0
5.02
4.22
iu/l
0.18
20
163
39
222
1.77
2.86
1.5
1.4
62.21
75.29
mu/l
0.11
34
199
29
150
1.95
2.85
2.4
2.3
—
—
—
0
0
91
638
1.45
2.83
2.4
2.3
410.91
822.01
ug/l
0.61
86
600
37
210
1.78
2.75
1.4
1.4
334.29
309.99
pmol/l
0.15
31
181
16
66
2.44
2.71
1.1
1.0
1.07
1.05
ratio
0.40
16
54
62
407
1.54
2.66
1.3
1.2
—
—
—
0
0
80
555
1.46
2.64
3.2
3.3
1.22
3.15
ratio
2.13
49
315
16
67
2.40
2.63
1.1
1.1
—
—
—
0
0
32
177
1.82
2.60
5.5
4.2
7.48
7.01
mmol/l
0.23
25
149
488
4297
1.18
2.58
1.4
1.4
—
—
—
0
0
56
365
1.55
2.50
1.1
1.1
4.37
5.21
eliau/ml
—
7
35
108
800
1.37
2.49
2.3
2.2
0.00
1.05
estimate
0.51
41
241
90
647
1.41
2.48
2.0
1.7
5.84
7.75
iu/ml
0.26
24
155
54
350
1.56
2.47
4.5
3.1
55.41
58.94
%
1.68
54
350
8
21
3.82
2.46
1.4
1.3
75.00
60.19
ug/l
—
8
21
23
116
1.99
2.46
1.6
1.5
13.81
12.95
umol/l
0.32
23
108
25
131
1.92
2.41
3.2
2.2
4.83
1.77
u/field
0.44
12
71
90
652
1.40
2.38
2.5
2.6
10.17
10.40
g/l
0.21
78
574
169
1346
1.28
2.37
4.9
3.5
1.23
1.23
mmol/l
0.13
146
1131
55
362
1.53
2.37
1.2
1.3
176.35
225.92
miu/ml
0.64
29
151
25
132
1.91
2.36
1.2
1.1
—
—
—
0
0
23
118
1.96
2.35
1.2
1.1
—
—
—
0
0
43
268
1.62
2.33
1.9
2.1
9549.30
4631.79
u/l
0.24
11
107
36
215
1.69
2.29
1.3
1.2
2.88
5.35
u/ml
0.95
17
97
136
1058
1.31
2.28
2.5
2.5
17.25
22.84
au/ml
0.64
17
98
32
185
1.74
2.28
2.5
2.3
0.99
1.10
g/24h
0.13
20
107
125
963
1.32
2.25
1.3
1.3
42.65
52.46
au/ml
0.36
12
79
1595
15461
1.20
2.23
6.7
6.0
2.55
2.68
mmol/l
7.27
1488
14232
81
585
1.40
2.20
3.3
3.4
279.92
320.91
mg/l
0.20
36
239
48
312
1.55
2.20
1.3
1.3
10.93
10.37
u/l
0.11
38
247
50
330
1.53
2.15
1.5
1.2
71.38
46.52
u/ml
—
8
35
9
30
3.01
2.14
2.0
3.1
287.56
4.80
ug/l
—
9
30
11
42
2.63
2.14
1.8
1.4
—
—
—
0
0
11
42
2.63
2.14
1.1
1.3
—
0.87
%
—
0
8
10
36
2.79
2.13
1.1
1.0
15.03
16.99
umol/l
—
10
28
51
339
1.52
2.13
4.6
2.7
10.43
8.94
pmol/l
0.37
51
339
180
1466
1.25
2.12
1.5
1.4
—
—
—
0
0
1567
15184
1.19
2.10
5.8
5.2
4.44
4.64
mmol/l
11.41
1469
14017
1557
15079
1.18
2.10
5.7
5.1
1.43
1.51
mmol/l
10.79
1449
13841
27
153
1.78
2.08
1.1
1.2
—
—
—
0
0
108
827
1.32
2.05
2.0
2.1
—
—
—
0
0
13
56
2.33
2.05
2.1
1.2
28.15
31.05
umol/l
0.49
13
49
27
154
1.76
2.04
1.0
1.2
—
—
—
0
0
15
70
2.15
1.98
1.9
2.6
1959.33
1868.31
ml
0.11
15
59
79
580
1.38
1.98
1.2
1.3
30.52
30.73
iu/l
0.02
65
493
27
156
1.74
1.96
1.1
1.1
0.30
3.18
u/ml
—
9
66
38
241
1.59
1.96
1.4
1.1
3.64
2.10
u/ml
0.19
22
117
15
71
2.12
1.92
2.6
1.9
1.10
2.86
u/field
—
10
54
86
649
1.34
1.83
1.1
1.1
—
—
—
0
0
14
66
2.13
1.82
1.0
1.1
0.35
1.18
u/ml
—
5
25
25
145
1.73
1.81
2.5
1.8
—
—
—
0
0
30
184
1.64
1.79
1.2
1.1
—
—
—
0
0
27
161
1.69
1.78
1.3
1.2
—
—
—
0
0
57
404
1.42
1.77
3.4
2.3
122.95
128.76
g/l
1.42
43
309
34
216
1.58
1.77
1.6
1.4
—
—
—
0
0
34
216
1.58
1.77
1.6
1.4
—
—
—
0
0
34
216
1.58
1.77
1.6
1.4
—
—
—
0
0
34
216
1.58
1.77
1.6
1.4
—
—
—
0
0
14
67
2.10
1.76
1.6
1.3
141.49
145.53
pmol/l
0.04
14
67
15
74
2.04
1.75
1.1
2.6
940.13
876.86
u/ml
0.08
15
74
126
1014
1.26
1.69
1.3
1.2
126.40
143.25
u/ml
0.22
44
372
8
31
2.59
1.66
2.1
1.5
—
—
—
0
0
5
14
3.58
1.61
1.8
3.3
0.40
0.64
u/field
—
5
14
8
32
2.51
1.59
1.4
1.4
—
—
—
0
0
18
99
1.83
1.57
1.7
1.3
—
—
—
0
0
43
298
1.45
1.54
1.8
2.1
5.47
5.32
mmol/24h
0.09
35
259
287
2524
1.16
1.54
3.4
3.4
0.72
0.78
ug/l
0.71
189
1658
29
185
1.58
1.51
1.0
1.1
2.03
1.96
eliau/ml
0.02
12
74
11
51
2.16
1.50
2.0
1.2
2.29
2.03
umol/l
0.53
11
41
24
147
1.64
1.47
1.8
1.3
—
—
—
0
0
31
203
1.54
1.46
1.2
1.1
0.21
1.45
u/ml
1.16
11
77
5
16
3.13
1.44
1.0
1.0
—
—
—
0
0
61
457
1.35
1.42
1.1
1.1
—
—
—
0
0
16
88
1.83
1.41
2.3
2.8
15.98
16.08
%
0.04
16
88
25
157
1.60
1.40
3.8
3.7
—
—
—
0
0
82
1036
0.78
1.39
1.3
1.4
—
—
—
0
0
27
174
1.56
1.37
1.4
1.6
67.47
61.87
%
0.24
15
109
9
41
2.20
1.37
1.2
1.7
57.56
782.07
nmol/24h
—
9
41
17
97
1.76
1.35
2.9
2.2
4.91
2.79
ug/l
0.51
17
90
26
168
1.56
1.31
1.7
1.4
52.82
28.63
ng/l
0.33
26
168
52
386
1.36
1.30
1.4
1.3
458.44
564.99
mg/l
1.99
52
370
31
209
1.49
1.30
1.2
1.1
3.61
4.22
u/ml
0.12
16
97
44
319
1.39
1.27
2.4
2.4
110.03
74.30
ug/min
0.29
29
190
23
146
1.58
1.26
1.0
1.1
0.09
0.35
u/ml
—
6
50
14
77
1.82
1.25
1.4
1.2
0.72
0.51
ratio
—
8
44
15
85
1.77
1.23
1.7
2.1
241.13
218.70
e6/l
0.17
15
77
13
71
1.84
1.19
1.2
1.3
—
0.43
g/l
—
0
5
6
26
2.31
1.18
1.2
1.0
—
—
—
0
0
26
175
1.49
1.13
1.3
1.4
0.16
0.33
nmol/l
2.15
16
133
30
209
1.44
1.10
2.1
1.7
—
—
—
0
0
29
202
1.44
1.07
1.1
1.3
—
—
—
0
0
25
169
1.49
1.07
1.1
1.1
0.86
2.06
u/ml
—
8
82
34
245
1.39
1.06
3.3
2.9
—
—
—
0
0
14
82
1.71
1.05
3.2
1.8
39.69
39.84
g/l
0.03
14
82
15
90
1.67
1.04
2.7
2.6
7.39
8.55
mmol/l
0.69
15
90
42
315
1.34
1.03
1.2
1.2
—
—
—
0
0
11
60
1.84
1.03
1.2
1.0
1236.00
1570.57
miu/ml
0.81
11
60
119
1013
1.19
1.01
2.5
2.3
12.71
12.85
nmol/l
0.06
106
911
21
139
1.52
1.00
1.4
1.4
18.84
31.89
%
0.83
12
86
19
123
1.55
0.99
2.4
2.6
42.94
30.73
mg/l
0.43
12
88
27
189
1.43
0.99
1.0
1.1
2.88
1.73
u/ml
—
9
94
136
1176
1.17
0.97
1.5
1.4
—
—
—
0
0
24
165
1.46
0.97
1.8
2.0
—
—
—
0
0
12
69
1.74
0.96
1.1
1.2
—
76.27
%
—
0
11
15
93
1.62
0.94
5.1
7.4
10.16
35.24
ug/l
—
10
54
44
339
1.31
0.92
1.4
1.3
144.97
370.47
e6/l
0.70
37
265
47
368
1.28
0.89
1.4
1.4
55.15
59.69
mmol/l
0.40
40
298
25
177
1.42
0.88
1.2
1.3
30.97
30.52
u/l
0.02
20
142
53
423
1.26
0.86
1.6
1.7
10281.48
14745.54
e6/l
0.59
33
292
30
222
1.36
0.84
1.1
1.1
99.00
2657.95
iu/ml
—
5
48
85
718
1.19
0.82
4.9
4.0
—
—
—
0
0
8
46
1.74
0.82
1.6
1.3
27.25
28.21
s
—
8
46
43
337
1.28
0.82
1.4
1.3
18.25
54.20
e6/l
0.63
32
253
33
251
1.32
0.78
2.5
1.8
—
—
—
0
0
14
90
1.56
0.78
2.2
1.6
87.00
80.68
umol/l
0.31
14
90
17
115
1.48
0.77
1.3
1.3
2.27
2.12
mmol/l
0.29
17
110
0
28
0.00
0.76
0.0
1.0
—
46.87
—
0
28
109
951
1.16
0.74
3.8
3.8
48.63
81.45
u/ml
0.66
104
910
9
56
1.61
0.72
4.1
1.7
39.89
29.66
%
—
9
56
42
335
1.26
0.72
2.0
1.6
—
—
—
0
0
10
60
1.67
0.72
1.8
1.3
11.20
9.73
mm/h
—
10
60
5
27
1.85
0.68
1.2
1.0
—
—
—
0
0
43
348
1.24
0.66
2.0
1.9
38.51
41.47
nmol/l
0.47
43
335
5
28
1.79
0.66
1.0
1.2
—
—
—
0
0
20
145
1.38
0.66
1.1
1.1
—
—
—
0
0
55
459
1.20
0.64
1.1
1.1
—
—
—
0
0
66
563
1.18
0.62
5.4
4.1
24.45
25.01
mmol/l
0.99
60
518
51
425
1.21
0.61
3.1
3.5
0.82
0.81
nmol/l
0.02
43
344
5
30
1.67
0.61
3.6
8.3
6.70
5.36
kpa
—
5
30
8
50
1.60
0.61
1.4
1.8
14.55
15.29
pmol/l
—
8
40
8
51
1.57
0.60
2.1
2.3
0.00
0.06
estimate
—
8
51
25
193
1.30
0.57
1.2
1.3
275.47
273.94
mosm/kgh2o
0.08
15
143
11
73
1.51
0.56
5.4
3.6
—
—
—
0
0
17
124
1.37
0.55
1.5
1.3
13.82
13.75
u/l
0.01
17
119
6
37
1.62
0.55
1.3
1.1
—
—
—
0
0
44
367
1.20
0.54
2.0
1.6
—
—
—
0
0
14
99
1.42
0.54
1.4
1.3
7.42
7.41
ph
—
8
67
44
368
1.20
0.53
2.0
1.6
—
—
—
0
0
33
268
1.24
0.52
2.1
1.5
—
—
—
0
0
10
66
1.52
0.52
5.7
3.8
—
—
—
0
0
44
369
1.20
0.52
2.0
1.6
—
—
—
0
0
25
197
1.27
0.51
1.6
1.6
—
—
—
0
0
44
370
1.19
0.51
2.0
1.6
—
—
—
0
0
16
118
1.36
0.50
3.1
1.9
37.41
38.81
%
0.14
16
118
16
118
1.36
0.50
1.2
1.1
—
—
—
0
0
22
171
1.29
0.50
1.0
1.2
—
—
—
0
0
17
127
1.34
0.49
1.2
1.1
—
—
—
0
0
7
46
1.52
0.48
1.9
1.2
3.66
2.71
mmol/l
—
7
40
24
190
1.27
0.48
2.0
2.2
0.73
0.88
mmol/l
0.09
24
183
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
3.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
4.86
—
0
16
5
35
1.43
0.39
1.0
1.3
—
—
—
0
0
10
71
1.41
0.39
2.8
2.4
506.80
501.77
min
—
10
47
0
19
0.00
0.39
0.0
2.9
—
0.69
—
0
19
12
159
0.75
0.38
1.4
1.4
—
—
—
0
0
27
224
1.21
0.38
1.1
1.1
—
—
—
0
0
27
224
1.21
0.38
1.1
1.1
—
—
—
0
0
25
206
1.22
0.38
1.8
1.7
—
—
—
0
0
50
440
1.14
0.37
1.5
1.2
0.87
0.90
g/l
0.58
50
440
21
171
1.23
0.35
1.6
2.4
—
—
—
0
0
22
181
1.22
0.34
1.5
1.7
—
2512.00
—
0
5
19
154
1.24
0.34
2.7
2.3
—
—
—
0
0
177
1670
1.07
0.33
5.9
4.4
7.36
7.35
ph
0.09
126
1163
12
154
0.78
0.32
1.1
1.1
—
—
—
0
0
10
75
1.34
0.30
1.1
1.8
—
—
—
0
0
7
55
1.27
0.30
1.3
1.9
—
—
—
0
0
13
163
0.80
0.29
1.4
1.6
—
—
—
0
0
23
194
1.19
0.29
1.4
1.3
—
—
—
0
0
25
213
1.18
0.29
1.6
1.3
21395.33
90716.70
e6/l
1.16
15
119
20
167
1.20
0.28
1.3
1.3
375263.64
100301.39
e6/l
0.49
11
115
22
186
1.18
0.28
2.5
2.9
—
—
—
0
0
19
159
1.20
0.26
1.0
1.3
7.19
7.41
mmol/l
0.12
19
135
19
160
1.19
0.25
1.5
1.3
—
—
—
0
0
22
189
1.17
0.24
1.5
1.3
6.58
6.46
mmol/l
0.09
22
180
16
134
1.20
0.23
1.6
1.2
8.81
11.81
u/l
0.72
16
126
7
92
0.76
0.22
1.3
1.2
—
—
—
0
0
7
94
0.74
0.22
1.0
1.1
—
12.92
—
0
26
5
42
1.19
0.21
4.4
1.8
1.12
1.42
ug/l
—
5
37
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
3.9
—
12.33
—
0
12
11
89
1.24
0.21
1.4
1.6
6.90
9.60
ug/l
0.62
11
77
14
117
1.20
0.20
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.08
—
0
14
0
14
0.00
0.20
0.0
1.0
—
20.17
—
0
6
0
14
0.00
0.20
0.0
5.8
—
0.19
—
0
14
6
49
1.23
0.20
1.5
2.5
—
—
—
0
0
28
250
1.12
0.19
2.0
2.0
0.88
0.87
%
0.05
21
173
12
99
1.21
0.19
3.4
1.6
15.78
18.35
nmol/l
0.59
12
90
6
52
1.15
0.19
1.3
1.2
69.63
51.67
%
—
6
44
7
61
1.15
0.17
1.1
1.1
—
—
—
0
0
7
63
1.11
0.17
11.0
11.4
0.65
0.63
mmol/l
—
7
58
23
205
1.12
0.17
1.8
1.4
—
—
—
0
0
14
120
1.17
0.16
2.1
1.6
125.14
106.32
ng/l
0.23
14
120
198
2041
0.97
0.16
5.5
5.1
34.00
33.39
%
0.32
138
1288
15
130
1.16
0.15
1.3
1.3
0.17
1.28
u/ml
—
8
69
22
197
1.12
0.15
1.3
1.2
—
—
—
0
0
26
237
1.10
0.14
1.5
1.3
1880.22
1634.25
e6/l
0.21
18
165
10
84
1.19
0.14
1.6
1.5
—
—
—
0
0
27
247
1.09
0.13
1.1
1.1
—
21.71
—
0
60
130
1344
0.96
0.13
2.3
2.1
3.38
3.46
ratio
0.31
99
1063
19
210
0.90
0.12
1.0
1.2
—
—
—
0
0
26
239
1.09
0.12
2.2
2.7
—
—
—
0
0
40
423
0.94
0.10
1.3
1.2
1.56
1.57
g/l
0.10
40
423
103
998
1.03
0.10
2.0
1.8
3.35
3.50
mmol/l
0.71
75
708
31
290
1.07
0.10
1.3
1.2
—
—
—
0
0
5
45
1.11
0.09
1.2
1.2
—
—
—
0
0
22
236
0.93
0.08
5.9
5.1
337.64
349.01
umol/l
0.17
22
209
7
66
1.06
0.08
1.4
1.2
128.71
161.18
mmol/24h
—
7
66
11
98
1.12
0.07
1.8
2.8
32.50
39.75
%
—
6
49
10
89
1.12
0.07
2.6
2.7
—
—
—
0
0
98
958
1.02
0.06
1.7
1.6
—
—
—
0
0
22
207
1.06
0.06
1.3
1.8
—
—
—
0
0
47
486
0.97
0.05
1.3
1.3
—
—
—
0
0
549
5459
1.01
0.04
3.9
3.2
—
—
—
0
0
40
388
1.03
0.04
1.2
1.1
0.69
0.66
ratio
—
6
55
11
119
0.92
0.04
1.0
1.0
795.00
693.74
ng/l
—
5
81
15
157
0.96
0.01
1.0
1.1
—
—
—
0
0
10
99
1.01
0.00
1.1
1.1
—
—
—
0
0
20
199
1.01
0.00
1.6
1.4
—
—
—
0
0
53
529
1.00
0.00
12.5
11.2
—
—
—
0
0
15
146
1.03
0.00
1.1
1.1
92.00
108.54
pmol/l
1.02
15
146
64
638
1.00
0.00
1.7
1.8
—
—
—
0
0
5
49
1.02
0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
16.00
—
0
9
0
9
0.00
0.00
0.0
1.7
—
329.67
—
0
9
0
5
0.00
-0.00
0.0
4.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
7.39
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
-0.00
1.5
1.3
136.13
138.77
nmol/l
—
8
80
0
7
0.00
-0.00
0.0
1.7
—
468.17
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.3
39.16
37.75
g/l
—
5
30
0
7
0.00
-0.00
0.0
1.1
—
90.29
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
217.33
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
9
92
0.98
-0.00
1.7
1.4
1.16
1.24
nmol/l
—
9
65
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_GALLBLAOTH and mortality.

Females

Parameter HR [95% CI] p-value
K11_GALLBLAOTH 1.493 [1.32, 1.69] < 0.001
Birth year 0.991 [0.98, 1.0] 0.034

During the follow-up period (1.1.1998 — 31.12.2019), 860 out of 3457 females with K11_GALLBLAOTH died.

Males

Parameter HR [95% CI] p-value
K11_GALLBLAOTH 1.511 [1.32, 1.74] < 0.001
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 816 out of 2490 males with K11_GALLBLAOTH died.

Mortality risk

Mortality risk for people of age

years, who have K11_GALLBLAOTH.

N-year risk Females Males
1 0.177% 0.305%
5 0.953% 1.729%
10 1.97% 4.354%
15 3.672% 8.803%
20 6.419% 14.59%

Relationships between endpoints

Index endpoint: K11_GALLBLAOTH – Other diseases of gallbladder

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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