Glaucoma, exfoliation

H7_GLAUCOMA_XFG

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H40.10
  • Hospital discharge: ICD-9 3651B
  • Hospital discharge: ICD-8 37512
  • Cause of death: ICD-10 H40.10
  • Cause of death: ICD-9 3651B
  • Cause of death: ICD-8 37512

2 out of 7 registries used, show all original rules.

5389

4. Check minimum number of events

None

5389

5. Include endpoints

None

5389

6. Filter based on genotype QC (FinnGen only)

4732

Control definitions (FinnGen only)

Control exclude
H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
H401
Name in latin
Glaucoma capsulare [primarium/residuale] cum syndromate exfoliationis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 50095 32712 16908
Only index persons 38107 25566 12541
Unadjusted period prevalence (%)
Whole population 0.78 0.94 0.47
Only index persons 0.79 0.94 0.48
Median age at first event (years)
Whole population 74.18 74.76 73.11
Only index persons 73.97 74.56 72.78

-FinnGen-

Key figures

All Female Male
Number of individuals 4732 2690 2042
Unadjusted period prevalence (%) 0.95 0.96 0.94
Median age at first event (years) 73.04 72.84 73.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4910
Matched controls
49092
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CS2P4
NOMESCO Finland
Optic nerve head imaging
61.9
322.7
179
30
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.1
317.1
2926
15903
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
140.4
307.7
163
12
S01ED01
ATC
timolol; ophthalmic
49.2
307.7
1439
410
H40
ICD-10 Finland
Glaucoma
58.2
307.7
372
69
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.7
307.7
1687
4917
S01EC04
ATC
brinzolamide; ophthalmic
139.1
307.7
2047
251
CHC05
NOMESCO Finland
Iridotomy
73.8
307.7
419
62
XCK00
NOMESCO Finland
Perimetry
30.0
307.7
1750
890
CHD00
NOMESCO Finland
Laser trabeculoplasty
1373.0
307.7
805
7
S01EE05
ATC
tafluprost; ophthalmic
66.1
307.7
1408
297
S01EA05
ATC
brimonidine; ophthalmic
363.1
307.7
1493
59
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.8
307.7
2312
6550
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.7
307.7
1346
2619
WX140
NOMESCO Finland
Parabulbar anesthesy
8.8
307.7
888
1198
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
307.7
580
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.9
307.7
3549
19596
S01EC54
ATC
brinzolamide, combinations; ophthalmic
220.7
307.7
733
39
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
91.1
307.7
201
23
S01ED02
ATC
betaxolol; ophthalmic
63.8
307.7
361
61
S01EA03
ATC
apraclonidine; ophthalmic
24.2
307.7
297
130
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
41.8
307.7
568
153
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
99196.6
307.7
4797
21
114
Kela drug reimbursment
Glaucoma
356.9
307.7
4299
949
S01EX03, ,
ATC
76.7
307.7
984
160
XCH05
NOMESCO Finland
Eye pressure longterm registration
117.8
307.7
278
25
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
41.2
307.7
527
143
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
4522.3
307.7
425
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
42.8
307.7
784
217
XCH00
NOMESCO Finland
Eye pressure measurement
11.2
307.7
916
985
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
3269.3
307.7
317
*
S01ED51
ATC
timolol, combinations; ophthalmic
149.2
307.7
3551
845
CHD35
NOMESCO Finland
Laser goniopuncture
+∞
307.7
327
*
S01EC01
ATC
acetazolamide; systemic
68.0
307.7
1056
197
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.8
307.7
1438
3281
XCK10
NOMESCO Finland
Photography of fundus of eye
4.3
307.7
1051
2894
H40.0
ICD-10 Finland
Glaucoma suspect
185.2
307.7
1684
138
H25.1
ICD-10 Finland
Senile nuclear cataract
3.1
307.7
3006
16462
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.4
307.7
738
1563
CS494
NOMESCO Finland
Other visual field testing
33.4
307.7
614
209
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
241.1
307.7
518
24
S01EE04
ATC
travoprost; ophthalmic
60.0
307.7
830
166
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
155.6
307.7
180
12
H40.9
ICD-10 Finland
Glaucoma, unspecified
164.2
307.7
643
45
H40.11
ICD-10 Finland
Low pressure glaucoma
97.4
307.7
336
37
S01EE01
ATC
latanoprost; ophthalmic
83.2
307.7
2738
733
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
667.9
307.7
1759
41
S01EE03
ATC
bimatoprost; ophthalmic
92.4
307.7
985
133
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2587.7
307.7
1695
10
S01EC03
ATC
dorzolamide; ophthalmic
98.5
307.7
731
87
S01EB01
ATC
pilocarpine; ophthalmic
56.2
307.7
316
60
F93
ICPC
Glaucoma
64.0
302.8
167
27
XCW10
NOMESCO Finland
Assessment of vision
11.7
264.5
276
248
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
246.5
3032
18252
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
242.7
231
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
230.0
219
*
ZXC20
NOMESCO Finland
Use of chemical agents
6.8
211.8
342
531
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.9
211.7
1340
5697
CHD99
NOMESCO Finland
Other filtering operation
1966.5
206.6
199
*
CFW99
NOMESCO Finland
Other operation on conjunctiva
841.3
166.8
163
*
S01EA02
ATC
dipivefrine; ophthalmic
338.2
164.1
165
5
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
160.3
153
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.7
152.9
219
297
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
5.1
150.5
329
679
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
13.5
147.0
139
106
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.6
142.9
964
4145
H34.8
ICD-10 Finland
Other retinal vascular occlusions
5.3
139.8
290
571
H27.1
ICD-10 Finland
Dislocation of lens
14.6
136.7
123
86
SPAT1009
SPAT
Measurement of intraocular pressure
8.1
133.0
181
231
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
128.7
123
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
12.6
128.5
126
102
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
1270.8
127.7
124
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
12.8
127.5
124
99
F38
ICPC
Eye, Other laboratory test NEC
6.9
124.0
196
296
H26.4
ICD-10 Finland
After-cataract
2.3
107.7
1041
5204
H40.1
ICD-10 Finland
Primary open-angle glaucoma
139.3
102.5
109
8
CFB00
NOMESCO Finland
Suture of conjunctiva
52.4
99.4
57
11
F43
ICPC
Eye, Other diagnostic procedure
5.9
98.2
179
312
H21.0
ICD-10 Finland
Hyphaema
17.4
96.4
79
46
H40.8
ICD-10 Finland
Other glaucoma
168.3
94.5
99
6
S01FA01
ATC
atropine; ophthalmic
11.8
90.3
92
79
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
863.4
86.9
85
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
82.1
662
3036
S01BC03
ATC
diclofenac; ophthalmic
4.2
79.3
217
534
H25.8
ICD-10 Finland
Other senile cataract
2.0
79.2
1053
5872
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
16.7
78.9
66
40
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
76.2
73
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
9.1
75.8
93
104
H27.8
ICD-10 Finland
Other specified disorders of lens
11.3
72.6
76
68
37512
ICD-8 Finland
Glaucoma, Chronicum capsulare
+∞
72.0
69
*
3708
FHL
Trabeculectomy or equivalent
708.4
71.3
70
*
CKD60
NOMESCO Finland
Anterior vitrectomy
5.9
71.2
128
220
CS444, ,
SPAT
34.9
71.1
45
13
S01BA07
ATC
fluorometholone; ophthalmic
5.5
70.3
137
254
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.5
69.9
459
1910
H18.1
ICD-10 Finland
Bullous keratopathy
15.1
69.1
61
41
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
9.4
68.4
82
89
H40.12
ICD-10 Finland
Pigmentary glaucoma
656.9
66.1
65
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
64.5
576
2744
H16.0
ICD-10 Finland
Corneal ulcer
3.3
64.4
256
811
H25.0
ICD-10 Finland
Senile incipient cataract
2.3
64.1
528
2431
ZXA05
NOMESCO Finland
Left side
1.7
63.9
1509
9979
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
62.6
60
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
9.5
62.5
74
79
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
25.5
61.5
43
17
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.6
60.9
205
584
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
59.5
57
*
CHD10
NOMESCO Finland
Trabeculectomy
+∞
58.4
56
*
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
154.4
58.0
61
*
CHC03
NOMESCO Finland
Laser iridoplasty
+∞
56.3
54
*
ZXA10
NOMESCO Finland
Bilateral
1.8
55.7
1117
7005
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
5.5
49.9
96
176
A98
ICPC
Health maint/preventive medicine
1.9
49.3
4238
37833
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
11.8
47.2
48
41
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
4.8
47.1
107
227
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
45.9
44
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
7.5
44.1
63
85
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
43.8
42
*
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
9.4
43.6
52
56
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
431.4
43.2
43
*
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.8
41.4
75
130
H44.5
ICD-10 Finland
Degenerated conditions of globe
60.6
41.2
48
8
ZXA00
NOMESCO Finland
Right side
1.5
39.5
1486
10766
H35.36
ICD-10 Finland
Macular cyst
5.1
38.1
80
159
H18.2
ICD-10 Finland
Other corneal oedema
11.2
38.0
40
36
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
370.1
37.0
37
*
S01BA04
ATC
prednisolone; ophthalmic
3.0
36.2
165
566
S01BC05
ATC
ketorolac; ophthalmic
2.2
35.7
330
1582
CKC12
NOMESCO Finland
Photocoagulation of retina
2.7
35.3
200
771
S01EX
ATC
Other antiglaucoma preparations
+∞
34.4
33
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
329.3
32.9
33
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
8.8
31.9
40
46
H01.0
ICD-10 Finland
Blepharitis
2.2
30.5
257
1187
WX002
NOMESCO Finland
Sedation and analgesia
1.5
29.5
981
6848
H54.4
ICD-10 Finland
Blindness, monocular
8.5
28.7
37
44
ZYC01
NOMESCO Finland
Remote contact by phone
2.2
28.5
254
1199
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.3
27.9
221
994
S01EX05
ATC
netarsudil; ophthalmic
+∞
27.1
26
*
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
75.6
26.8
30
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
4.8
26.1
59
125
Z94.7
ICD-10 Finland
Corneal transplant status
6.3
25.2
42
67
F99
ICPC
Eye/adnexa disease other
4.5
25.2
61
137
H16.9
ICD-10 Finland
Keratitis, unspecified
3.5
24.7
86
251
CG2T4
NOMESCO Finland
Topography assessment of cornea
4.4
24.3
60
137
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.3
24.0
92
286
H31.4
ICD-10 Finland
Choroidal detachment
37.7
23.9
30
8
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.7
23.6
468
2873
Z3231
NOMESCO Finland
Registered nurse
1.4
23.5
1280
9779
CFW10
NOMESCO Finland
Conjunctival manipulation with a needle (needling)
+∞
22.9
22
*
N02BE01
ATC
paracetamol; systemic, rectal
1.5
22.8
4150
38498
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.8
22.5
322
1797
XCD20
NOMESCO Finland
Photoangiography of eye
2.6
22.5
126
484
S01FA04
ATC
cyclopentolate; ophthalmic
3.8
22.4
68
181
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.1
22.4
215
1045
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
5.3
22.3
44
83
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
21.8
1918
15799
H57.1
ICD-10 Finland
Ocular pain
2.5
21.5
140
578
H20.8
ICD-10 Finland
Other iridocyclitis
6.8
21.2
33
49
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
21.1
2706
23528
H26.2
ICD-10 Finland
Complicated cataract
3.5
20.4
70
203
H3603, E103,
ICD-10 Finland
6.9
20.3
31
45
F29
ICPC
Eye symptom/complaint other
1.7
20.3
433
2706
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
20.8
19.9
29
14
SPAT1325
SPAT
Vaccination
1.3
19.3
1744
14352
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.4
19.1
135
579
CFD10
NOMESCO Finland
Repair of conjunctiva
26.1
19.1
26
10
SPAT1312
SPAT
General health counselling
1.4
17.9
1276
10115
ZXD20
NOMESCO Finland
Day surgery
1.5
17.7
533
3609
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
3.8
17.7
53
140
XCH00, ,
SPAT
22.8
17.7
25
11
H54.1
ICD-10 Finland
Severe visual impairment, binocular
7.8
17.4
24
31
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
1.7
17.3
349
2150
S01AD03
ATC
aciclovir; ophthalmic
2.1
17.1
168
825
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
16.7
639
4547
S01XA18
ATC
ciclosporin; ophthalmic
4.2
16.6
43
102
S18
ICPC
Laceration/cut
1.3
16.2
2105
18072
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
16.0
1614
13398
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
16.0
2492
21877
S01BA01
ATC
dexamethasone; ophthalmic
2.1
15.9
158
779
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.2
15.9
131
601
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
12.9
15.6
27
21
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
15.6
1040
8133
R42
ICD-10 Finland
Dizziness and giddiness
1.3
15.4
1274
10281
SFA20
NOMESCO Finland
Two-surface restoration
1.3
15.2
1861
15817
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
3.4
15.2
53
156
H02.4
ICD-10 Finland
Ptosis of eyelid
2.1
15.1
146
713
SPAT1263
SPAT
Sampling
1.3
14.9
1830
15545
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
15.1
14.8
24
16
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.3
14.8
112
496
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
3.4
14.6
51
150
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
14.6
1097
8722
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
10.0
13.9
27
27
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
2.7
13.9
73
273
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
13.5
13
*
CHB30
NOMESCO Finland
Goniotomy
+∞
13.5
13
*
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
+∞
13.5
13
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.7
13.4
222
1296
F28
ICPC
Limited function/disability (F)
3.4
13.4
47
139
J01DB01
ATC
cefalexin; oral
1.3
13.4
3505
32419
Z01.2
ICD-10 Finland
Dental examination
1.3
13.3
1488
12451
SPAT1301
SPAT
No procedures
1.3
13.2
1506
12631
H44.4
ICD-10 Finland
Hypotony of eye
40.2
13.1
16
*
H54.5
ICD-10 Finland
Severe visual impairment, monocular
4.1
13.0
35
86
SFA10
NOMESCO Finland
One-surface restoration
1.3
12.7
1835
15811
H27.0
ICD-10 Finland
Aphakia
4.8
12.6
28
59
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
5.5
12.6
24
44
CHC10
NOMESCO Finland
Peripheral iridectomy
32.1
12.6
16
5
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
+∞
12.5
12
*
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
24.3
12.4
17
7
CGG60
NOMESCO Finland
Reinforcement of sclera using graft
130.3
12.4
13
*
S01EB02
ATC
carbachol; ophthalmic
130.3
12.4
13
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
12.4
2176
19141
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
12.4
1347
11210
WX199
NOMESCO Finland
Other local analgesia
1.8
12.4
179
1004
SPAT1310
SPAT
Counselling related to known health issue
1.3
12.2
1307
10850
EB1VA, ,
NOMESCO Finland
1.4
12.1
506
3651
WZC00, ,
SPAT
1.4
12.1
539
3934
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.3
11.9
1163
9541
R53
ICD-10 Finland
Malaise and fatigue
1.3
11.9
1212
9997
H52.1
ICD-10 Finland
Myopia
2.5
11.8
70
279
XCH05, ,
SPAT
16.4
11.6
18
11
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
11.6
1052
8544
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.7
11.5
225
1374
WW200, ,
SPAT
1.3
11.5
1158
9528
H40.21
ICD-10 Finland
Intermittent glaucoma with closed ventricular angle
+∞
11.5
11
*
3656
FHL
Combined cataract glaucoma surgery
+∞
11.5
11
*
3702
FHL
Trabeculotomy
+∞
11.5
11
*
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
11.4
86
382
SPAT1153
SPAT
Removal of sutures
1.3
11.3
1386
11677
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
11.1
927
7444
CKC15
NOMESCO Finland
Panretinal photocoagulation
2.9
11.0
49
168
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
10.9
1407
11921
K02.1
ICD-10 Finland
Caries of dentine
1.2
10.5
1856
16249
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
3.8
10.5
31
82
SDA03
NOMESCO Finland
Periodontal treatment
1.3
10.4
1195
9979
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
32.6
10.3
13
*
H52.2
ICD-10 Finland
Astigmatism
2.6
10.3
57
220
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
10.2
1807
15814
SPAT1053
SPAT
Memory test
1.3
10.2
959
7815
J01CA04
ATC
amoxicillin; systemic
1.2
10.0
3268
30369
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
2.5
9.9
62
254
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
4.0
9.8
27
68
H10.5
ICD-10 Finland
Blepharoconjunctivitis
2.4
9.7
64
268
H3601, E103,
ICD-10 Finland
4.0
9.5
26
65
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
2.1
9.4
85
407
H53.1
ICD-10 Finland
Subjective visual disturbances
1.5
9.4
258
1713
3652B
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[KROONINEN AHDASKULMAGLAUKOOMA]
+∞
9.4
9
*
CHD30
NOMESCO Finland
Laser trabeculectomy
+∞
9.4
9
*
CHD60
NOMESCO Finland
Deep sclerectomy without implant
+∞
9.4
9
*
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
2.4
9.4
62
261
SPAT1014
SPAT
Treatment of eyes
1.9
9.3
106
553
H13
ICPC
Plugged feeling ear
1.3
9.2
940
7722
L57.0
ICD-10 Finland
Actinic keratosis
1.3
9.2
647
5064
P20
ICPC
Memory disturbance
1.3
9.2
976
8062
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
3.3
9.1
33
100
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
9.1
1444
12453
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.3
9.1
845
6867
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
9.0
878
7175
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
2.2
8.9
70
317
S01AX11
ATC
[U] ofloxacin
1.6
8.9
188
1175
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
8.8
1066
8930
SFA30
NOMESCO Finland
Three-surface restoration
1.2
8.8
1353
11628
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
8.7
776
6273
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
8.6
1487
12923
SPAT1043
SPAT
Audiometry
1.3
8.6
530
4072
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
8.6
854
6992
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
8.6
1279
10953
N06AX11
ATC
mirtazapine; oral
1.2
8.5
1411
12207
H18.8
ICD-10 Finland
Other specified disorders of cornea
3.5
8.5
28
80
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.3
8.5
710
5687
H02.1
ICD-10 Finland
Ectropion of eyelid
2.1
8.4
77
371
3719
FHL
Other measure in this category
90.2
8.4
9
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
2.0
8.4
91
468
CHC04
NOMESCO Finland
Ventricular angle laser gonoplasty
+∞
8.3
8
*
3703
FHL
Laser operation on ventricular angle under general anesthesia
+∞
8.3
8
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
8.3
8
*
G04CB01
ATC
finasteride; oral
1.3
8.2
568
4435
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.3
8.2
533
4126
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
14.5
8.2
13
9
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
7.5
8.1
18
24
QAE15
NOMESCO Finland
Excision of other superficial lesion of skin from head and neck
4.5
8.1
19
42
DFF00
NOMESCO Finland
Pure tone audiometry
1.3
8.1
472
3598
AA1AD
NOMESCO Finland
CT of head and brain
1.2
8.0
1523
13338
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
8.0
1200
10268
CJW99
NOMESCO Finland
Other operation on lens
10.0
8.0
15
15
S01BA09
ATC
clobetasone; ophthalmic
7.2
7.9
18
25
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
1.3
7.9
525
4075
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
2.4
7.9
52
219
N17
ICPC
Vertigo/dizziness
1.3
7.9
652
5214
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
4.6
7.9
18
39
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.4
7.8
308
2200
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
10.8
7.8
14
13
SPAT1097
SPAT
Recording of ECG
1.3
7.8
685
5521
SPAT1260
SPAT
Consultation of another employee
1.3
7.8
739
6012
CJF35
NOMESCO Finland
Correcting the position of the artificial lens and attaching it to the sclera
45.0
7.7
9
*
CHC00
NOMESCO Finland
Iridotomy
45.0
7.7
9
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
1.9
7.7
98
532
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
7.4
7.7
17
23
CWW99
NOMESCO Finland
Other reoperation on eye and adjacent structures
18.4
7.6
11
6
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
18.4
7.6
11
6
Z00.0
ICD-10 Finland
General medical examination
1.3
7.5
773
6348
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
2.1
7.4
67
322
R4110
NOMESCO Finland
Physiotherapy
0.8
7.4
846
10085
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
1.4
7.4
412
3119
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
1.6
7.3
171
1096
H26.02
ICD-10 Finland
Presenil cataract
1.9
7.3
81
420
3711
FHL
Cyclodiateria or cryocoagulation
+∞
7.3
7
*
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
7.3
7
*
CHB50
NOMESCO Finland
Trabeculotomy
+∞
7.3
7
*
WZC30
NOMESCO Finland
Teaching
1.3
7.3
610
4884
JAB30
NOMESCO Finland
Repair of inguinal hernia using prosthetic material
1.3
7.2
405
3068
E0000UV, ,
ATC
1.2
7.2
1662
14784
CG2S4
NOMESCO Finland
Photography of cornea
3.5
7.1
23
65
CDC00
NOMESCO Finland
Enucleation of eye
20.0
7.1
10
5
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
3.1
7.1
28
90
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
3.2
7.1
27
85
-1, ,
NOMESCO Finland
1.2
7.1
971
8221
DAX08
NOMESCO Finland
Fitting of hearing aid
1.4
7.0
318
2327
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.3
7.0
479
3734
SPAT1081
SPAT
Cardiorespiratory global assessment
1.4
7.0
273
1949
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
2.0
6.9
69
345
A44
ICPC
General and Unspecified, Preventive immunization/medic
1.4
6.9
291
2104
SPAT1304
SPAT
Counselling and guidance related to ageing
1.3
6.9
488
3821
C08CA01
ATC
amlodipine; oral
1.2
6.9
2024
18351
CJF20
NOMESCO Finland
Removal of artificial lens
7.5
6.9
15
20
XKD00
NOMESCO Finland
Uroflowmetry
1.3
6.8
707
5804
L17
ICPC
Foot/toe symptom/complaint
1.2
6.8
1247
10856
CKD40
NOMESCO Finland
Endophotocoagulation of retina
2.2
6.8
54
248
CKB00
NOMESCO Finland
Puncture and evacuation of suprachorioidal fluid
40.1
6.8
8
*
R21
ICPC
Throat symptom/complaint
1.3
6.7
471
3682
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.4
6.7
339
2526
Z01.8
ICD-10 Finland
Other specified special examinations
1.2
6.7
852
7159
H33.0
ICD-10 Finland
Retinal detachment with retinal break
1.7
6.6
111
655
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
2.3
6.6
45
193
H02
ICPC
Hearing complaint
1.2
6.6
747
6194
G04CA01
ATC
alfuzosin; oral
1.3
6.6
489
3855
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
3.6
6.6
21
59
D82
ICPC
Teeth/gum disease
1.2
6.5
1025
8788
F01
ICPC
Eye pain
1.8
6.5
86
473
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.2
6.5
873
7369
G04CA02
ATC
tamsulosin; oral
1.2
6.5
1093
9436
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.3
6.5
625
5090
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.2
6.4
848
7145
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.3
6.4
469
3687
K05.18
ICD-10 Finland
Chronic gingivitis
1.5
6.4
195
1327
L30.8
ICD-10 Finland
Other specified dermatitis
1.8
6.4
95
543
N06AX26
ATC
vortioxetine; oral
1.5
6.3
192
1308
3651D
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA PIGMENTOSUM]
+∞
6.2
6
*
37511
ICD-8 Finland
Glaucoma, Chronicum irritativum sive congestivum
+∞
6.2
6
*
3651E
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA INFANTILE SEU JUVENILE]
+∞
6.2
6
*
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
2.8
6.2
30
109
3661A
ICD-9 Finland
Cataract, Senile cataract
1.7
6.1
96
557
S01AA12
ATC
tobramycin; ophthalmic
3.3
6.1
22
67
F13
ICPC
Eye sensation abnormal
1.7
6.1
95
550
Z5132
NOMESCO Finland
Nursing associate professional
2.8
6.1
28
99
WX144
NOMESCO Finland
Subconjunctival anesthesy
2.0
6.0
65
335
H84
ICPC
Presbyacusis
1.4
6.0
248
1787
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.4
6.0
233
1662

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
4317
38705
1.95
50.50
30.4
31.8
30.50
30.37
pg
5.37
4253
38012
4317
38705
1.95
50.50
30.4
31.9
92.19
91.93
fl
3.27
4254
38011
4317
38706
1.95
50.48
30.6
31.9
238.29
241.64
e9/l
2.66
4220
37588
4317
38706
1.95
50.48
30.5
31.9
4.28
4.30
e12/l
1.70
4199
37417
4317
38707
1.95
50.46
30.9
32.4
38.84
38.75
%
0.43
4254
37999
4317
38711
1.95
50.38
30.8
32.2
129.73
129.44
g/l
0.62
4258
38045
4317
38714
1.95
50.33
30.5
32.0
6.83
7.03
e9/l
4.83
4198
37422
4279
38295
1.91
49.71
25.3
26.3
139.45
139.48
mmol/l
0.23
4198
37422
4280
38328
1.91
49.32
25.4
26.6
4.01
4.01
mmol/l
0.09
4194
37404
4302
38599
1.92
49.13
27.7
28.7
82.71
84.15
umol/l
1.82
4239
37872
4147
36894
1.80
47.18
19.7
21.3
26.42
28.38
mg/l
3.23
3578
31869
4213
37767
1.81
45.24
12.9
13.3
22.70
23.45
u/l
1.40
4044
36178
3889
34379
1.63
40.66
5.6
5.4
4.42
4.40
mmol/l
0.46
3489
30868
3979
35385
1.66
40.51
6.5
6.3
2.49
2.48
mmol/l
0.33
3569
31724
3869
34180
1.62
40.32
6.0
5.7
2.08
2.08
mu/l
0.03
3456
30687
3972
35392
1.64
39.14
5.9
5.9
6.08
6.11
mmol/l
0.81
3515
31288
3848
34060
1.60
38.58
5.5
5.3
1.50
1.47
mmol/l
4.14
3419
30327
3898
34631
1.61
38.22
7.6
7.5
40.75
40.70
mmol/mol
0.15
3501
31353
3694
32664
1.53
34.44
4.6
4.5
1.20
1.26
mmol/l
9.06
3243
28606
2020
16089
1.43
31.54
4.9
5.0
2.06
0.62
estimate
0.49
494
3811
3338
29380
1.42
27.95
4.7
4.7
14.46
15.83
mm/h
5.33
3056
26925
3555
31689
1.44
27.43
7.6
8.3
82.61
83.86
u/l
0.48
3346
29718
3273
28771
1.41
27.12
5.6
5.5
2658.21
1.63
—
5
42
2613
22223
1.38
25.72
4.8
4.8
2.51
3.22
estimate
0.10
637
4919
2615
22363
1.36
24.20
4.9
4.8
1.68
0.29
estimate
0.39
603
4614
3278
29105
1.38
23.60
6.0
6.0
3341.89
3205.27
e6/l
0.03
55
495
3239
28747
1.37
23.08
4.8
4.5
15.22
15.24
pmol/l
0.20
2858
25572
1591
12661
1.38
22.85
4.9
4.9
0.00
0.00
estimate
1.15
548
4192
2548
21921
1.34
21.54
4.8
4.8
0.00
0.00
estimate
1.34
614
4689
1386
10919
1.37
20.75
4.2
4.4
0.18
0.56
estimate
1.09
491
3629
1929
16057
1.33
19.90
4.5
4.4
0.50
0.76
—
6
41
3189
28525
1.34
19.74
24.4
26.5
13.95
14.06
%
4.00
3141
28095
3056
27169
1.33
19.72
4.9
4.9
0.44
1508.10
—
9
67
2195
18649
1.32
19.46
4.7
4.7
72.26
94.42
ng/l
0.28
1767
15061
1256
9857
1.37
18.94
5.3
5.2
1.02
1.17
kg/l
0.51
882
6760
2947
26204
1.31
18.21
4.9
5.1
6.85
6.89
mmol/l
0.52
2818
24980
1503
12213
1.33
17.80
6.7
6.3
3.77
4.67
ug/l
0.60
1333
10814
2481
21637
1.30
17.33
2.4
2.4
96.02
93.88
pmol/l
1.28
1251
11124
2646
23306
1.29
16.96
19.5
20.7
1.36
1.39
inr
1.58
2305
19706
1297
10436
1.33
16.12
1.8
1.8
21896823.10
15695952.84
pmol/l
0.19
1023
8289
1641
13686
1.30
15.61
2.4
2.5
3.01
3.07
mg/l
0.46
1414
11656
2457
21628
1.27
15.01
4.3
4.8
34.54
34.31
g/l
1.21
2272
19930
2066
17838
1.27
14.68
4.2
4.2
6.34
6.33
ph
0.18
1182
9419
2201
19227
1.26
13.92
2.5
2.4
81.16
80.92
nmol/l
0.15
1925
16640
1772
15111
1.27
13.65
1.8
1.8
20.74
20.12
nmol/l
0.85
1485
12581
1209
9833
1.30
13.50
5.6
5.2
22.31
22.37
%
0.05
669
5410
2043
17827
1.25
12.61
3.0
3.2
141.43
148.55
ug/l
0.51
1838
16077
2734
24703
1.24
12.07
6.8
7.0
1.22
1.21
mmol/l
0.58
2316
21056
1986
17475
1.23
10.79
3.9
4.0
—
—
—
0
0
1623
13991
1.24
10.67
2.6
2.6
60.72
67.65
u/l
0.59
1497
12794
2417
21777
1.22
10.16
3.1
3.3
49.95
57.21
u/l
3.18
2180
19682
2560
23198
1.22
10.15
7.9
9.0
4.23
4.41
e9/l
3.26
2217
19736
3057
28197
1.22
10.13
27.2
28.4
330.39
329.86
g/l
2.55
3031
27926
452
3318
1.40
9.77
5.1
6.1
24.37
24.62
mmol/l
0.70
430
3176
2312
20810
1.21
9.60
5.6
5.9
1.78
1.84
e9/l
0.40
2014
17738
347
2438
1.46
9.56
4.3
4.4
1.55
1.54
%
0.07
330
2312
1707
14950
1.22
9.31
2.2
2.2
189.35
214.32
u/l
0.78
1603
13985
323
2254
1.46
9.23
4.4
4.6
0.91
0.86
%
1.02
305
2136
1727
15213
1.21
8.73
4.1
4.1
8.05
9.46
mg/mmol
0.35
1075
9295
2319
21006
1.20
8.64
5.6
6.0
0.20
0.19
e9/l
0.60
1997
17755
654
5180
1.30
8.53
1.7
1.8
—
—
—
0
0
1593
13950
1.21
8.51
2.0
1.9
1.23
1.28
mmol/l
2.76
1278
11307
2262
20465
1.19
8.48
5.5
5.8
0.04
0.04
e9/l
1.57
1936
17022
1680
14807
1.20
8.35
3.4
3.4
34.38
48.09
mg/l
3.73
1078
9392
912
7557
1.25
8.24
4.4
4.8
—
—
—
0
0
1761
15631
1.20
8.02
2.4
2.4
—
—
—
0
0
1979
17757
1.19
7.97
3.3
3.5
1866.17
2011.22
ng/l
0.66
1715
15599
2245
20369
1.19
7.96
5.5
5.8
0.62
0.63
e9/l
0.76
1927
16920
217
1449
1.52
7.74
4.8
5.5
1.30
1.36
mmol/l
0.44
195
1291
1684
14935
1.19
7.65
3.5
3.3
6.60
6.58
mmol/l
0.05
1398
12207
1105
9419
1.22
7.62
3.8
3.8
—
—
—
0
0
32
107
3.00
7.60
1.1
1.1
—
—
—
0
0
160
1005
1.61
7.47
5.3
6.1
104.88
104.95
mmol/l
0.06
146
899
160
1005
1.61
7.47
5.3
6.1
11.02
11.20
mmol/l
0.31
146
898
1233
10646
1.21
7.44
1.8
1.8
1193.56
1156.76
nmol/l
0.69
912
7818
2534
23337
1.18
7.25
5.7
6.3
12.82
12.45
umol/l
0.41
2405
22115
1852
16730
1.17
6.48
3.1
3.4
2.35
2.36
mmol/l
2.93
1680
14811
2402
22144
1.17
6.47
5.9
6.3
1.21
1.21
mmol/l
1.38
2181
20147
2107
19308
1.16
5.97
5.7
6.2
25.22
25.25
%
0.04
1969
18047
2084
19100
1.16
5.85
5.8
6.2
9.24
9.18
%
0.41
1919
17624
2078
19041
1.16
5.85
5.8
6.2
0.65
0.64
%
0.16
1915
17574
869
7418
1.21
5.75
1.3
1.3
0.73
1.55
u/ml
7.78
232
1750
2058
18876
1.16
5.66
5.6
6.0
59.28
59.35
%
0.09
1948
17784
582
4775
1.25
5.64
3.1
3.2
4.48
4.96
e9/l
1.34
477
3855
2075
19047
1.15
5.64
5.7
6.1
2.93
2.77
%
2.15
1912
17591
533
4346
1.25
5.46
2.2
2.2
0.00
0.01
estimate
1.02
104
744
456
3656
1.27
5.39
3.9
4.2
0.02
0.30
%
2.13
101
1028
455
3679
1.26
5.02
3.7
4.0
0.12
0.11
%
0.09
109
1109
473
3849
1.25
4.94
3.7
4.0
0.95
0.96
%
0.02
126
1275
448
3637
1.25
4.78
3.6
3.9
0.73
0.76
%
0.07
126
1192
977
11063
0.85
4.60
3.8
4.1
84.33
83.11
%
0.82
960
10821
2089
19372
1.14
4.57
2.6
3.0
—
—
estimate
—
0
0
128
872
1.48
4.31
1.2
1.3
—
—
—
0
0
811
7074
1.18
4.14
3.8
3.6
0.79
0.87
ug/l
1.62
609
5171
201
1496
1.36
4.13
3.5
3.4
1.51
1.68
mmol/l
1.98
193
1464
482
4011
1.22
4.12
2.7
2.6
0.40
0.54
e6/l
1.02
467
3877
274
2138
1.30
4.07
1.9
2.2
0.00
0.49
estimate
0.53
77
537
40
202
1.99
4.05
1.1
1.1
—
—
—
0
0
488
4073
1.22
4.05
3.5
3.9
1.23
1.23
mmol/l
0.88
417
3439
373
4564
0.80
4.04
7.1
6.9
—
—
—
0
0
296
2337
1.28
4.02
2.2
2.2
—
—
—
0
0
61
356
1.72
3.95
1.9
1.8
191.39
200.95
pmol/l
0.26
54
334
1217
11045
1.14
3.55
2.9
2.9
5.63
5.58
e6/l
0.05
1118
10030
333
2709
1.25
3.55
2.5
2.5
—
—
—
0
0
1227
11142
1.13
3.55
3.6
3.7
0.10
0.07
0.21
60
469
348
4221
0.81
3.50
2.6
2.4
296.82
39.29
u/l
0.51
286
3524
243
1912
1.28
3.43
1.3
1.3
—
—
—
0
0
983
8838
1.14
3.29
2.4
2.6
11.44
11.45
umol/l
0.01
892
8062
573
4958
1.18
3.23
4.5
4.7
7.35
7.37
ph
0.79
380
3471
393
3297
1.21
3.14
4.7
4.9
—
—
—
0
0
510
4382
1.18
3.13
1.3
1.3
—
—
—
0
0
469
4002
1.19
3.12
2.2
1.9
141.93
163.53
ug/g
0.65
364
3092
1838
17191
1.11
3.11
13.1
12.9
0.00
0.00
e9/l
0.48
1558
13768
56
343
1.64
3.11
1.2
1.1
—
—
—
0
0
126
916
1.39
3.09
1.9
1.8
10.98
12.94
mg/l
1.36
116
832
1175
10737
1.12
3.02
2.9
3.1
2.46
2.47
mmol/l
6.28
1071
9471
191
1493
1.29
2.89
4.8
5.0
—
—
—
0
0
107
1468
0.72
2.83
3.9
3.6
1.61
1.91
index
0.30
41
752
605
5319
1.16
2.79
5.5
5.3
34.31
34.12
%
0.15
369
3248
89
625
1.43
2.70
1.0
1.0
—
—
—
0
0
1068
9766
1.12
2.69
3.1
3.2
506.76
519.68
mosm/kgh2o
1.38
945
8525
260
3156
0.81
2.68
7.2
7.4
24.38
24.33
mmol/l
0.10
252
3053
1610
15062
1.10
2.62
4.0
4.4
—
—
—
0
0
412
4779
0.85
2.60
5.9
5.9
1.34
1.41
mmol/l
0.49
403
4669
59
885
0.66
2.58
1.3
1.2
—
—
—
0
0
167
1309
1.29
2.52
3.9
3.5
7.67
7.81
mmol/l
0.24
160
1280
573
5058
1.15
2.52
5.8
6.9
120.13
118.51
g/l
1.29
556
4942
218
1767
1.24
2.49
1.3
1.3
193.62
237.76
u/ml
0.27
199
1611
175
1383
1.27
2.48
1.5
1.4
240.79
269.74
ug/g
1.26
119
847
545
4804
1.15
2.45
2.4
2.5
4.85
6.61
ug/l
3.87
446
4002
523
4599
1.15
2.43
1.4
1.4
—
—
—
0
0
263
2187
1.21
2.37
2.4
2.5
12.45
22.45
au/ml
2.08
13
134
599
5352
1.14
2.22
2.4
2.4
68.36
67.57
e9/l
0.20
480
3912
619
5546
1.13
2.20
5.4
6.4
95.61
95.08
%
1.43
589
5341
511
4523
1.14
2.18
1.3
1.3
484.56
512.09
titre
0.14
114
1082
1025
9454
1.11
2.18
1.3
1.3
—
—
—
0
0
904
8308
1.11
2.06
2.3
2.6
2.25
2.25
g/l
0.12
822
7535
142
1124
1.27
2.04
1.3
1.3
55.93
59.74
mmol/l
0.68
115
889
235
1966
1.20
2.03
1.3
1.3
57.82
55.79
au/ml
0.05
11
134
1659
15690
1.09
2.03
3.6
3.7
106.19
84.46
e6/l
0.23
1356
12111
672
6083
1.12
2.02
1.3
1.3
34.39
39.78
iu/ml
0.42
219
1845
50
335
1.50
2.00
2.0
1.6
102.61
107.98
ng/l
0.20
50
335
5
11
4.55
1.94
2.2
1.5
272.26
256.95
nmol/l
—
5
11
1804
17146
1.08
1.94
4.3
4.4
121.13
137.62
e6/l
0.31
1380
12360
1592
15056
1.08
1.93
3.8
4.0
7.40
7.40
ph
0.88
1198
10868
75
547
1.38
1.93
2.3
2.5
10.02
10.66
mmol/l
0.89
75
537
56
388
1.45
1.92
1.0
1.1
31.24
34.53
mmol/l
0.56
48
318
0
52
0.00
1.88
0.0
1.2
—
0.77
—
0
10
130
1034
1.26
1.83
1.6
1.6
—
—
—
0
0
34
526
0.64
1.82
2.1
2.1
177.95
639.13
u/ml
0.43
34
516
239
2027
1.19
1.81
2.6
2.1
12.08
11.55
nmol/l
0.32
208
1729
36
230
1.57
1.81
2.3
1.7
85.56
94.20
umol/l
0.99
36
230
542
4888
1.12
1.76
3.8
3.3
237.09
258.75
ng/l
0.45
506
4487
1178
11042
1.09
1.76
2.7
2.9
352.78
359.35
umol/l
1.28
984
9284
678
6192
1.11
1.76
5.3
6.2
1.11
1.05
mmol/l
0.15
520
5042
42
281
1.50
1.73
1.4
1.3
—
—
—
0
0
405
3594
1.14
1.71
3.9
3.4
6.13
6.09
ph
0.36
296
2636
958
8916
1.09
1.68
1.5
1.7
1.59
1.61
mg/l
0.05
774
7046
24
141
1.71
1.67
1.9
1.5
0.20
0.19
nmol/l
0.05
16
100
1289
12153
1.08
1.66
3.3
3.1
35.49
36.17
u/l
0.07
1193
11310
325
2854
1.15
1.62
7.0
8.2
16.00
15.61
%
2.13
312
2753
834
7737
1.09
1.58
2.4
2.6
20.34
20.47
%
0.11
764
7064
34
508
0.67
1.58
1.2
1.2
—
—
—
0
0
61
447
1.37
1.58
1.4
1.2
318.23
317.79
nmol/l
0.00
47
339
14
261
0.53
1.57
1.2
1.2
—
—
—
0
0
41
281
1.46
1.54
1.4
1.3
6.18
6.99
g/l
1.15
30
212
41
281
1.46
1.54
1.4
1.3
3.12
2.85
g/l
0.35
30
214
41
281
1.46
1.54
1.4
1.3
0.37
0.46
g/l
0.92
30
214
34
224
1.52
1.53
1.0
1.1
1.64
13.88
nmol/l
—
9
60
130
1062
1.23
1.50
1.2
1.2
—
—
—
0
0
41
284
1.45
1.47
1.4
1.4
—
1554.29
—
0
7
675
6230
1.10
1.44
5.4
6.3
7.41
7.42
ph
0.41
436
3451
309
2730
1.14
1.44
4.3
4.1
1.02
1.02
ratio
0.13
276
2464
451
4976
0.90
1.43
2.5
2.5
11.27
10.01
umol/l
0.39
391
4348
48
345
1.39
1.42
1.2
1.2
83.12
228.97
miu/ml
2.63
11
85
26
400
0.65
1.41
1.5
1.2
3.63
5.37
u/ml
—
8
195
150
1783
0.84
1.38
3.8
3.4
0.82
0.83
nmol/l
0.07
117
1427
1296
12306
1.07
1.37
5.9
6.5
—
—
—
0
0
410
3702
1.12
1.35
2.1
2.1
394.84
390.81
nmol/l
0.12
360
3344
48
349
1.38
1.34
1.5
1.2
100.50
104.60
pmol/l
0.19
48
349
53
393
1.35
1.32
2.2
1.3
16.54
12.33
u/l
0.91
41
317
281
3170
0.88
1.32
1.4
1.4
—
—
—
0
0
90
719
1.26
1.31
2.0
1.7
4.23
4.35
mmol/24h
0.14
77
597
91
728
1.25
1.30
2.1
2.1
32.22
32.33
pg
0.08
91
721
300
2667
1.13
1.29
3.6
3.3
24.91
25.20
mmol/l
0.78
289
2595
736
6856
1.09
1.29
2.3
2.3
1.79
1.80
%
0.10
638
5968
68
526
1.30
1.28
1.5
1.5
65.20
60.37
%
0.46
41
333
114
1374
0.83
1.24
1.5
1.8
21.16
21.35
s
0.21
96
1263
1047
9902
1.07
1.24
4.5
4.5
315.75
408.09
ng/l
0.35
921
8799
26
171
1.52
1.22
1.1
1.1
—
—
—
0
0
701
6532
1.09
1.22
2.0
2.0
—
—
—
0
0
670
6237
1.09
1.20
5.4
6.2
12.02
11.79
kpa
0.54
641
5947
670
6239
1.09
1.19
5.4
6.2
5.05
5.08
kpa
0.21
641
5953
21
133
1.58
1.17
1.1
1.2
131.10
157.10
mmol/24h
0.76
21
133
45
599
0.75
1.14
1.3
1.2
—
—
—
0
0
1127
10716
1.07
1.14
5.0
4.5
0.24
0.10
0.35
21
191
42
309
1.36
1.13
1.2
1.2
107.80
39.04
u/ml
—
5
18
431
4697
0.91
1.12
5.5
5.9
11.86
11.68
mmol/l
0.18
405
4419
8
40
2.00
1.12
1.1
1.0
—
—
—
0
0
99
1193
0.83
1.11
1.3
1.6
11900.76
16681.25
e6/l
0.85
71
806
7
31
2.26
1.10
1.1
1.1
—
—
—
0
0
7
31
2.26
1.10
1.1
1.1
—
—
—
0
0
7
31
2.26
1.10
1.1
1.1
—
—
—
0
0
240
2133
1.13
1.08
3.1
3.1
4.38
4.32
pmol/l
0.34
210
1834
356
3905
0.90
1.07
1.4
1.4
—
—
—
0
0
18
113
1.59
1.05
1.1
1.3
37.30
35.53
%
—
10
77
14
228
0.61
1.03
1.4
1.5
—
—
—
0
0
41
306
1.34
1.03
2.4
2.2
3.27
2.06
ug/l
0.85
34
258
58
731
0.79
1.01
1.1
1.1
—
—
—
0
0
336
3060
1.11
1.00
1.5
1.5
—
—
—
0
0
15
91
1.65
1.00
1.5
1.6
1.19
1.19
mmol/l
0.03
15
85
59
466
1.27
1.00
1.3
1.2
—
—
—
0
0
52
405
1.29
0.98
1.3
1.4
74.00
52.08
titre
—
5
24
64
512
1.25
0.98
3.3
4.2
59.50
57.70
u/ml
0.02
64
498
685
6441
1.07
0.98
1.4
1.5
2.57
2.70
g/l
0.64
391
3495
456
4220
1.09
0.97
3.1
3.4
90.86
94.97
ng/l
0.37
372
3470
19
284
0.67
0.97
2.7
2.2
—
—
—
0
0
33
446
0.74
0.96
1.1
1.2
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
32.11
—
0
9
18
117
1.54
0.93
1.2
1.1
1.02
1.08
ratio
1.35
12
84
17
109
1.56
0.93
1.1
1.4
—
—
—
0
0
34
454
0.75
0.93
1.2
1.1
300.86
300.70
u/ml
0.00
21
252
305
3340
0.91
0.91
1.5
1.5
—
—
—
0
0
41
530
0.77
0.89
3.6
4.2
—
—
—
0
0
21
143
1.47
0.89
2.4
2.9
26.67
29.59
umol/l
0.79
12
107
12
194
0.62
0.88
1.1
1.3
1519.84
379.29
ug/l
—
5
100
815
8573
0.94
0.88
3.3
3.3
1.18
1.31
e6/l
0.52
494
4654
83
694
1.20
0.87
2.2
2.2
33.14
26.57
mg/l
0.33
21
228
36
471
0.76
0.87
1.1
1.1
—
—
—
0
0
53
423
1.26
0.85
1.3
1.4
291.67
323.86
titre
—
6
44
118
1020
1.16
0.84
3.5
4.0
32.49
30.35
mg/l
0.23
85
738
151
1329
1.14
0.84
2.1
2.3
125.73
125.05
g/l
0.14
125
1016
25
341
0.73
0.81
1.4
1.2
—
—
—
0
0
103
885
1.17
0.80
2.2
2.0
0.94
0.89
%
0.43
75
611
0
24
0.00
0.79
0.0
1.6
—
—
—
0
0
9
147
0.61
0.78
1.2
1.8
—
—
—
0
0
60
492
1.22
0.78
1.6
1.6
0.77
0.88
g/l
0.38
45
388
211
1907
1.11
0.78
1.8
2.0
1331.54
602.00
ug/l
0.36
198
1810
19
132
1.44
0.75
1.4
1.4
19.47
23.18
%
0.38
14
112
65
540
1.21
0.75
2.9
2.6
—
—
—
0
0
46
368
1.25
0.75
3.1
3.0
16.75
28.41
mg/l
0.75
29
276
15
99
1.52
0.75
1.0
1.1
0.71
0.68
umol/24h
—
5
41
29
218
1.33
0.74
1.3
1.5
60.55
67.86
%
0.65
20
179
149
1324
1.13
0.74
1.1
1.1
—
148.44
titre
—
0
25
1404
13593
1.05
0.74
3.5
3.6
0.43
0.54
e6/l
1.29
1119
10193
16
231
0.69
0.73
3.8
3.9
—
—
—
0
0
174
1563
1.12
0.73
3.0
3.8
7.41
7.41
ph
0.34
174
1538
17
242
0.70
0.72
2.1
2.2
93.40
62.45
ug/min
—
5
56
7
39
1.80
0.72
1.0
1.2
—
—
—
0
0
44
544
0.81
0.71
1.2
1.3
—
—
—
0
0
26
194
1.34
0.71
1.6
1.4
2.17
2.84
%
—
6
43
25
186
1.35
0.69
1.0
1.2
8.98
12.98
umol/l
0.44
13
119
12
77
1.56
0.68
1.0
1.1
—
—
—
0
0
61
726
0.84
0.68
1.4
1.4
95961.06
60339.72
e6/l
0.29
32
417
16
110
1.46
0.68
1.4
1.8
0.00
0.05
estimate
0.80
16
110
36
284
1.27
0.67
1.1
1.1
—
—
—
0
0
758
7913
0.95
0.65
3.4
3.4
2.69
2.88
e6/l
0.25
437
3991
18
128
1.41
0.65
1.3
2.4
—
—
—
0
0
69
808
0.85
0.65
1.4
1.5
10551.94
2788.52
e6/l
0.39
49
565
5
29
1.72
0.64
1.4
1.0
—
—
—
0
0
285
2645
1.08
0.63
1.2
1.2
—
—
—
0
0
173
1570
1.11
0.63
1.3
1.3
—
—
—
0
0
42
513
0.82
0.62
1.0
1.0
—
—
—
0
0
263
2837
0.92
0.62
1.4
1.5
—
—
—
0
0
54
451
1.20
0.62
1.3
1.4
22.57
30.55
ng/l
0.98
54
451
17
121
1.41
0.62
1.0
1.0
—
—
—
0
0
44
534
0.82
0.62
1.2
1.1
—
—
—
0
0
20
147
1.36
0.61
1.1
1.0
1.03
1.49
u/ml
—
9
74
138
1240
1.12
0.61
12.7
13.0
—
—
—
0
0
134
1203
1.12
0.60
2.4
2.4
1.92
1.83
mg/l
0.46
113
1028
9
138
0.65
0.60
2.2
2.0
9.02
57.38
u/l
—
9
130
9
140
0.64
0.60
1.6
1.1
—
—
—
0
0
22
165
1.33
0.60
1.3
1.5
22.18
18.88
%
0.24
17
151
0
21
0.00
0.60
0.0
1.3
—
178.11
—
0
9
227
2094
1.09
0.60
2.9
2.8
—
—
—
0
0
33
411
0.80
0.59
1.3
1.2
—
—
—
0
0
108
958
1.13
0.59
1.2
1.3
3.64
5.12
u/ml
0.56
20
154
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
25
192
1.30
0.59
1.3
1.5
4.52
6.88
u/l
1.56
17
159
20
149
1.34
0.57
1.5
1.6
11.63
1731.91
u/l
—
6
54
55
647
0.85
0.57
1.4
1.5
—
—
—
0
0
12
81
1.48
0.57
1.3
1.9
1.41
1.17
ug/l
0.19
12
75
28
220
1.27
0.56
1.0
1.1
—
—
—
0
0
55
466
1.18
0.56
1.9
2.3
2.11
1.40
u/field
0.28
27
239
8
55
1.46
0.56
10.9
14.8
3.57
5.01
mmol/l
—
8
55
17
229
0.74
0.55
2.2
1.6
—
—
—
0
0
15
107
1.40
0.55
2.3
1.4
8.45
6.16
mmol/l
0.79
15
107
366
3453
1.06
0.54
3.6
3.0
126.69
126.24
g/l
0.15
349
3354
107
957
1.12
0.53
1.2
1.2
21.58
3.62
u/ml
0.48
16
96
602
5771
1.05
0.51
1.3
1.3
16.63
14.09
u/ml
0.28
228
1913
6
40
1.50
0.51
1.2
1.6
—
—
—
0
0
6
40
1.50
0.51
1.2
1.8
—
—
—
0
0
273
2557
1.07
0.51
1.2
1.3
—
—
—
0
0
16
214
0.75
0.51
3.8
4.1
—
—
—
0
0
40
333
1.20
0.50
1.5
1.3
—
—
—
0
0
591
5668
1.05
0.50
1.2
1.3
—
—
—
0
0
61
702
0.87
0.50
5.1
5.9
12.54
12.99
mg/l
0.29
54
642
76
669
1.14
0.50
5.0
7.0
7.32
7.45
mmol/l
0.14
63
550
17
127
1.34
0.49
2.2
2.0
0.63
0.62
mmol/l
0.27
17
127
30
243
1.24
0.49
1.2
1.3
1.56
1.56
g/l
0.00
30
243
250
2340
1.07
0.49
1.9
1.9
3.58
2.18
ug/l
0.45
205
1994
115
1040
1.11
0.49
1.3
1.3
—
—
—
0
0
213
1982
1.08
0.49
1.2
1.3
—
—
—
0
0
7
107
0.65
0.48
1.0
1.2
—
17.43
%
—
0
21
58
502
1.16
0.48
4.3
4.1
327.68
333.17
umol/l
0.11
50
423
79
890
0.89
0.48
1.5
1.5
—
—
—
0
0
24
190
1.26
0.47
6.9
6.2
6.49
28.24
ug/l
1.35
14
108
32
263
1.22
0.47
5.4
5.2
34.00
61.65
u/ml
—
5
85
140
1283
1.09
0.46
1.2
1.2
0.70
1.03
u/ml
0.25
14
111
55
633
0.87
0.46
1.3
1.4
—
—
—
0
0
502
4808
1.05
0.46
2.6
2.5
66.09
65.56
g/l
0.75
438
4263
24
191
1.26
0.46
1.2
1.5
4.12
2.87
%
0.27
17
159
5
83
0.60
0.45
12.0
1.2
—
—
—
0
0
34
283
1.20
0.44
2.9
2.6
—
—
—
0
0
191
1779
1.08
0.44
1.1
1.2
132.67
117.67
u/ml
0.19
61
603
11
152
0.72
0.44
1.0
1.2
—
73.67
%
—
0
21
62
704
0.88
0.44
1.4
1.5
—
—
—
0
0
22
175
1.26
0.43
1.0
1.0
0.94
0.48
u/ml
—
7
98
8
57
1.40
0.42
1.6
1.5
51.00
52.21
umol/l
—
8
57
0
15
0.00
0.41
0.0
1.1
—
0.12
—
0
6
0
16
0.00
0.41
0.0
1.2
—
1.55
—
0
11
14
105
1.33
0.41
1.4
1.5
—
0.25
—
0
25
487
4679
1.05
0.41
3.3
2.9
4.38
4.34
kpa
0.13
472
4551
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
11
79
1.39
0.40
1.2
1.6
14.18
15.03
mm/h
0.11
11
79
585
5644
1.04
0.40
3.8
3.9
28.91
25.88
ug/l
0.06
501
4679
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
17
215
0.79
0.39
1.5
1.4
0.19
1.52
u/ml
1.95
12
132
11
148
0.74
0.38
1.2
1.7
9542.83
29375.47
e6/l
—
6
78
773
7507
1.04
0.38
1.7
1.9
29.65
29.93
s
0.44
744
7281
86
947
0.91
0.38
1.1
1.1
—
—
—
0
0
5
36
1.39
0.38
2.4
1.6
11.94
8.22
mg/l
—
5
31
439
4567
0.96
0.38
1.8
2.0
0.20
0.19
g/l
0.70
396
4205
9
67
1.34
0.38
5.6
8.9
6.23
5.12
kpa
—
9
67
59
524
1.13
0.37
2.3
2.1
—
—
—
0
0
209
2215
0.94
0.37
2.0
1.9
1.34
1.39
g/l
0.12
184
1998
130
1401
0.93
0.36
1.5
1.6
3.95
7.13
iu/ml
1.82
30
329
12
157
0.76
0.35
1.1
1.2
—
—
—
0
0
12
90
1.33
0.35
1.2
1.2
—
—
—
0
0
5
80
0.62
0.35
1.0
1.1
—
—
—
0
0
9
124
0.73
0.35
1.2
1.2
—
—
—
0
0
11
145
0.76
0.34
1.2
1.2
54.26
12.65
pmol/l
—
5
51
92
844
1.09
0.33
1.7
1.8
3.14
3.35
mmol/l
1.04
68
616
57
510
1.12
0.33
1.2
1.3
277.60
268.40
pmol/l
0.08
52
411
24
285
0.84
0.32
1.1
2.6
6.95
7.00
mmol/l
0.04
15
194
44
388
1.14
0.32
1.6
1.4
26.33
28.21
%
0.12
24
245
62
686
0.90
0.32
1.5
1.6
—
—
—
0
0
21
252
0.83
0.32
1.7
1.9
488.67
494.19
min
0.12
15
170
26
220
1.18
0.31
1.1
1.1
—
—
—
0
0
21
251
0.84
0.31
1.2
1.1
—
—
—
0
0
13
164
0.79
0.30
5.2
1.2
—
—
—
0
0
7
99
0.71
0.30
1.1
1.1
—
9.93
—
0
14
26
221
1.18
0.30
1.1
1.1
—
—
—
0
0
25
212
1.18
0.30
2.3
2.3
10.92
35.82
iu/ml
—
5
38
7
55
1.27
0.30
1.0
1.4
—
—
—
0
0
115
1073
1.07
0.29
1.8
2.2
62.41
75.41
ug/min
0.25
61
589
218
2287
0.95
0.29
3.7
4.0
—
—
—
0
0
27
232
1.16
0.28
1.6
2.0
10.21
2.32
u/field
0.77
19
155
52
575
0.90
0.28
3.1
3.8
61.85
58.66
%
0.58
40
473
31
270
1.15
0.28
1.1
1.1
0.99
0.90
u/ml
0.05
13
149
27
312
0.86
0.28
1.1
1.0
380.43
308.24
ng/l
0.59
14
205
43
480
0.89
0.27
1.2
1.2
154.42
161.14
au/ml
0.13
12
140
9
120
0.75
0.27
1.2
1.5
—
—
—
0
0
272
2828
0.96
0.26
1.8
1.6
1.50
1.55
g/l
0.39
232
2420
53
481
1.10
0.26
1.2
1.3
—
—
nmol/l
—
0
0
18
214
0.84
0.26
1.2
1.1
—
—
—
0
0
22
188
1.17
0.25
1.8
1.9
0.58
0.59
e9/l
0.05
22
175
47
518
0.91
0.24
1.9
1.6
—
—
—
0
0
55
503
1.09
0.24
1.2
1.3
0.22
0.20
nmol/l
0.71
48
410
86
803
1.07
0.23
3.3
3.1
56.54
59.65
%
1.14
86
803
23
199
1.16
0.23
1.9
1.9
92.22
292.51
e6/l
0.56
23
187
28
317
0.88
0.23
1.6
1.4
—
—
—
0
0
69
743
0.93
0.23
1.4
1.3
16.80
35.71
e6/l
0.54
54
553
1297
12793
1.02
0.22
3.5
3.6
0.00
30.36
estimate
—
10
84
14
167
0.84
0.21
4.9
1.2
—
—
—
0
0
14
167
0.84
0.21
4.9
1.2
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
1.58
1.71
umol/24h
—
5
42
179
1716
1.04
0.21
2.9
2.8
693.79
386.28
mg/l
0.42
73
659
0
12
0.00
0.21
0.0
1.0
—
8.81
—
0
12
0
12
0.00
0.21
0.0
1.0
—
0.08
—
0
12
789
8026
0.98
0.20
2.5
2.8
0.83
0.81
mmol/l
2.88
723
7381
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
28
313
0.89
0.20
1.1
1.0
784.14
687.67
ng/l
0.45
14
199
676
6636
1.02
0.19
4.3
5.0
1.06
1.04
mmol/l
0.80
609
6062
34
308
1.10
0.19
1.1
1.1
—
—
—
0
0
120
1257
0.95
0.18
1.2
1.4
—
—
—
0
0
120
1256
0.95
0.18
1.2
1.4
—
16.22
—
0
32
25
223
1.12
0.18
1.3
2.0
13.97
25.27
umol/l
—
6
24
548
5585
0.98
0.18
1.4
1.4
—
—
—
0
0
285
2771
1.03
0.18
2.5
2.8
10.79
10.67
g/l
0.11
256
2528
87
917
0.95
0.17
1.8
2.1
30.24
32.00
umol/l
0.22
70
793
5
67
0.75
0.17
1.0
1.4
—
—
—
0
0
8
68
1.18
0.16
5.1
2.9
34.75
66.98
u/l
—
8
63
22
196
1.12
0.16
1.2
1.2
0.53
0.64
ratio
—
8
53
63
669
0.94
0.16
2.3
1.4
0.78
0.82
nmol/l
0.19
56
542
14
162
0.86
0.16
5.1
1.2
—
—
—
0
0
221
2276
0.97
0.16
2.5
2.4
2.78
2.98
g/l
1.97
191
1986
34
370
0.92
0.16
1.5
1.3
—
—
—
0
0
71
750
0.95
0.15
1.5
1.4
702.54
970.71
e6/l
0.31
59
593
6
77
0.78
0.15
1.0
1.3
27.17
27.93
s
—
6
77
6
78
0.77
0.15
1.3
1.4
—
—
—
0
0
73
770
0.95
0.15
1.3
1.2
3.89
3.88
mmol/l
0.04
68
715
209
2152
0.97
0.15
2.5
2.3
10.50
10.24
g/l
0.25
171
1835
16
182
0.88
0.15
1.1
1.0
—
—
—
0
0
27
296
0.91
0.14
1.2
1.5
—
—
—
0
0
239
2453
0.97
0.14
2.4
2.3
3.68
3.71
g/l
0.07
208
2164
73
693
1.05
0.14
2.3
2.9
—
—
—
0
0
540
5487
0.98
0.14
3.7
3.4
1.53
1.91
mmol/l
1.85
448
4761
84
880
0.95
0.14
3.1
3.9
1.59
1.53
%
0.06
71
758
200
2056
0.97
0.14
3.6
4.4
55.63
104.34
u/ml
1.23
191
1968
240
2460
0.97
0.14
2.4
2.3
7.21
7.56
g/l
2.76
210
2168
97
930
1.04
0.14
1.6
1.7
2.65
10.65
iu/l
0.60
27
332
283
2894
0.98
0.13
1.4
1.6
—
—
—
0
0
117
1214
0.96
0.13
2.3
2.0
3.17
3.33
ratio
0.97
96
987
11
128
0.86
0.13
6.0
1.2
—
—
—
0
0
21
232
0.90
0.13
1.1
1.1
—
—
—
0
0
178
1831
0.97
0.13
1.3
1.3
—
—
—
0
0
31
335
0.92
0.13
1.1
1.1
—
—
—
0
0
240
2457
0.98
0.13
2.4
2.3
4.18
4.20
g/l
0.18
210
2170
42
448
0.94
0.13
1.1
1.3
190054.70
153029.47
e6/l
0.08
20
292
57
540
1.06
0.12
1.4
1.3
269.59
273.85
mosm/kgh2o
0.96
44
372
46
433
1.06
0.12
1.0
1.1
13.30
634.19
iu/ml
—
7
70
35
326
1.07
0.12
1.2
1.2
7.77
8.03
mmol/l
0.25
29
261
19
210
0.90
0.12
1.1
1.0
—
—
—
0
0
67
639
1.05
0.12
2.5
2.4
—
—
—
0
0
36
336
1.07
0.12
1.9
2.1
15.77
15.72
%
0.04
36
336
50
528
0.95
0.12
2.1
2.0
—
—
—
0
0
51
538
0.95
0.12
3.3
3.4
13.06
12.01
index
0.32
18
276
41
386
1.06
0.11
4.1
3.1
—
—
—
0
0
85
882
0.96
0.11
1.3
1.2
40.14
46.53
u/l
0.27
75
758
16
177
0.90
0.10
1.0
1.1
—
13.45
—
0
40
14
156
0.90
0.10
4.9
1.2
—
—
—
0
0
36
339
1.06
0.10
1.8
1.9
7.96
8.31
mmol/l
0.24
36
339
5
45
1.11
0.09
1.0
1.7
45.24
38.94
pmol/l
—
5
35
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
19
207
0.92
0.09
1.1
1.1
—
3.38
iu/ml
—
0
8
31
330
0.94
0.09
1.8
1.8
—
—
—
0
0
14
126
1.11
0.09
1.5
1.8
—
—
—
0
0
84
867
0.97
0.08
1.3
1.2
522.35
621.89
mg/l
0.76
78
820
567
5613
1.01
0.08
3.6
3.4
5.75
5.82
kpa
0.98
551
5475
10
113
0.88
0.08
1.2
1.1
—
—
—
0
0
10
113
0.88
0.08
1.2
1.1
—
—
—
0
0
10
113
0.88
0.08
1.2
1.1
—
—
—
0
0
5
65
0.77
0.08
1.0
1.1
—
—
—
0
0
13
117
1.11
0.08
1.1
1.2
—
—
—
0
0
64
618
1.04
0.07
2.0
2.2
0.93
1.10
g/24h
0.25
35
342
12
133
0.90
0.07
2.6
2.4
—
—
—
0
0
11
98
1.12
0.07
1.8
1.4
—
—
—
0
0
12
108
1.11
0.07
1.3
1.4
101.50
499.10
nmol/24h
0.83
12
108
8
78
1.03
0.07
15.3
11.2
0.57
0.63
mmol/l
—
8
72
64
620
1.03
0.07
1.2
1.2
—
—
—
0
0
8
93
0.86
0.06
1.9
1.4
—
—
—
0
0
1107
11010
1.01
0.06
2.4
2.6
—
—
—
0
0
98
957
1.02
0.06
1.3
1.4
0.23
0.31
mg/l
1.51
39
344
1456
14497
1.01
0.06
2.4
2.6
—
—
—
0
0
192
1891
1.02
0.06
3.0
3.0
13924.21
1743.12
u/ml
0.44
166
1591
337
3334
1.01
0.06
3.4
3.8
7.41
7.42
ph
1.87
282
2765
127
1247
1.02
0.05
1.4
1.5
—
—
—
0
0
339
3421
0.99
0.05
3.4
3.8
5.14
5.16
kpa
0.16
319
3207
574
5701
1.01
0.05
3.6
3.4
7.37
7.38
ph
1.04
360
3382
102
1001
1.02
0.05
1.3
1.3
—
—
—
0
0
55
565
0.97
0.04
1.1
1.1
—
—
—
0
0
10
109
0.92
0.04
6.6
6.5
14.02
13.61
%
—
10
109
87
884
0.98
0.03
1.3
1.2
—
—
—
0
0
21
201
1.04
0.03
2.0
2.5
38.64
38.24
%
0.04
14
110
10
108
0.93
0.03
1.2
1.0
1591.30
1654.02
miu/ml
—
10
108
54
551
0.98
0.03
1.3
1.2
—
—
—
0
0
12
112
1.07
0.03
10.3
1.4
—
—
—
0
0
25
259
0.96
0.02
2.4
1.7
—
—
—
0
0
209
2105
0.99
0.02
3.3
3.0
55.63
80.93
mg/l
0.46
179
1800
32
329
0.97
0.02
1.3
1.3
7.37
7.43
ph
0.64
23
224
20
208
0.96
0.02
1.2
3.5
61.83
63.48
mg/l
0.05
12
131
92
910
1.01
0.02
1.3
1.5
30.00
30.35
g/l
0.10
82
819
62
611
1.01
0.01
2.0
1.9
90.05
88.91
%
1.20
62
603
190
1911
0.99
0.01
3.3
2.9
2.10
3.73
ratio
1.56
136
1173
13
123
1.06
0.01
1.2
1.2
0.79
0.49
ratio
—
6
71
53
522
1.02
0.01
1.3
1.3
—
—
—
0
0
53
522
1.02
0.01
1.3
1.3
—
—
—
0
0
53
522
1.02
0.01
1.3
1.3
—
—
—
0
0
53
522
1.02
0.01
1.3
1.3
—
—
—
0
0
32
313
1.02
0.01
1.2
1.2
—
—
—
0
0
36
367
0.98
0.01
1.9
2.1
729.64
645.09
ml
0.19
22
219
116
1152
1.01
0.01
1.2
1.2
—
—
—
0
0
10
106
0.94
0.01
5.4
5.9
8.53
8.54
mmol/l
—
10
106
12
126
0.95
0.00
1.5
1.9
15.71
319.46
ug/l
0.76
12
117
17
164
1.04
0.00
1.6
1.6
2.63
11.97
nmol/l
1.64
11
135
19
184
1.03
0.00
1.1
1.1
63.32
41.89
mg/l
0.61
14
155
23
224
1.03
0.00
1.0
1.0
0.35
1.26
u/ml
—
6
95
102
1026
0.99
0.00
3.4
4.4
2.59
2.87
mmol/l
0.50
69
713
14
137
1.02
0.00
1.1
1.1
314.60
298.25
ng/l
—
5
36
103
1026
1.00
0.00
3.5
4.4
5.03
5.04
kpa
0.05
103
998
12
117
1.03
0.00
1.1
1.1
—
—
—
0
0
17
173
0.98
0.00
1.4
1.1
160.94
133.78
nmol/l
0.83
17
173
210
2100
1.00
0.00
3.3
3.0
38.09
61.39
mg/l
1.73
181
1797
103
1031
1.00
0.00
3.5
4.4
8.52
8.25
kpa
0.99
103
1002
108
1078
1.00
0.00
2.5
3.1
163.87
856.91
u/ml
1.76
101
976
12
115
1.04
0.00
1.5
2.4
6.08
332.49
ug/l
0.71
12
115
24
235
1.02
0.00
1.6
1.7
38.84
39.25
g/l
0.14
24
235
116
1161
1.00
0.00
2.8
3.9
—
—
—
0
0
125
1246
1.00
0.00
1.5
1.6
59.60
29.92
u/ml
0.46
20
176
14
141
0.99
0.00
1.7
1.9
4.64
7.69
%
1.21
14
132
40
398
1.00
0.00
1.3
1.4
—
—
—
0
0
23
229
1.00
0.00
1.0
1.0
0.88
2.01
u/ml
—
7
107
14
135
1.04
0.00
1.7
1.9
24.86
31.46
%
0.75
14
135
177
1775
1.00
0.00
3.9
4.1
24.40
25.00
mmol/l
1.48
158
1558
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
3260.00
—
0
5
5
51
0.98
0.00
2.4
3.1
0.60
0.53
u/field
—
5
51
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
1.25
—
0
6
0
5
0.00
0.00
0.0
1.8
—
363.60
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
1.26
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
516.11
—
0
9
5
59
0.85
0.00
1.2
1.2
67.34
43.47
mg/l
—
5
49
5
53
0.94
-0.00
1.6
1.3
—
—
—
0
0
7
71
0.99
-0.00
1.4
2.6
0.73
0.67
ug/l
—
7
71
6
66
0.91
-0.00
1.0
1.0
18.02
16.67
umol/l
—
6
52
9
89
1.01
-0.00
1.6
1.4
164.88
152.18
pmol/l
—
9
89
9
90
1.00
-0.00
1.0
2.6
17.62
19.25
mu/l
—
9
80
6
60
1.00
-0.00
2.5
1.6
1.28
3.06
mmol/l
—
6
49
6
60
1.00
-0.00
1.2
1.2
17.57
16.53
g/l
—
6
53

Mortality – FinRegistry

Association

Association between endpoint H7_GLAUCOMA_XFG and mortality.

Females

Parameter HR [95% CI] p-value
H7_GLAUCOMA_XFG 0.876 [0.82, 0.94] < 0.001
Birth year 0.994 [0.99, 1.0] 0.178

During the follow-up period (1.1.1998 — 31.12.2019), 9065 out of 22936 females with H7_GLAUCOMA_XFG died.

Males

Parameter HR [95% CI] p-value
H7_GLAUCOMA_XFG 0.91 [0.84, 0.99] 0.032
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 4878 out of 11833 males with H7_GLAUCOMA_XFG died.

Mortality risk

Mortality risk for people of age

years, who have H7_GLAUCOMA_XFG.

N-year risk Females Males
1 0.071% 0.185%
5 0.498% 0.955%
10 1.294% 2.41%
15 2.583% 4.733%
20 4.311% 7.942%

Relationships between endpoints

Index endpoint: H7_GLAUCOMA_XFG – Glaucoma, exfoliation

GWS hits: 25

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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