Vascular dementia (subcortical)

VD_SC

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F01.2
  • Cause of death: ICD-10 F01.2

2 out of 7 registries used, show all original rules.

1645

4. Check minimum number of events

None

1645

5. Include endpoints

None

1645

6. Filter based on genotype QC (FinnGen only)

1456

Control definitions (FinnGen only)

Control exclude
F5_DEMENTIA, G6_ALZHEIMER, G6_AD_STRICT

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F01
Name in latin
Dementia vascularis subcorticalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1456 643 813
Unadjusted period prevalence (%) 0.31 0.23 0.37
Median age at first event (years) 81.57 82.84 80.56

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1491
Matched controls
14910
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N06DA02
ATC
donepezil; oral
102.1
307.7
315
39
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
1177.5
307.7
359
*
N06DX01
ATC
memantine; oral
154.5
307.7
510
50
F01.2
ICD-10 Finland
Subcortical vascular dementia
795.6
307.7
519
10
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
859.6
307.7
799
20
G30.1
ICD-10 Finland
Alzheimer disease with late onset
137.4
307.7
372
36
F01.9
ICD-10 Finland
Vascular dementia, unspecified
127.9
307.7
237
22
P20
ICPC
Memory disturbance
8.5
307.7
735
1523
N06DA03
ATC
rivastigmine; oral, transdermal
147.0
307.7
256
21
N05AX08
ATC
risperidone; systemic
13.5
307.7
431
436
F03
ICD-10 Finland
Unspecified dementia
30.1
307.7
277
112
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
10.4
307.7
565
823
P70
ICPC
Dementia
24.2
235.4
172
80
G30.8
ICD-10 Finland
Other Alzheimer disease
113.2
224.7
115
11
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
88.6
203.1
107
13
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
54.4
194.5
111
22
N06DA04
ATC
galantamine; oral
252.4
176.5
178
8
A28
ICPC
Limited function/disability NOS
4.3
171.7
768
2935
N05AH04
ATC
quetiapine; oral
5.7
167.6
377
835
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
229.1
123.8
126
6
R41.3
ICD-10 Finland
Other amnesia
8.3
120.4
167
222
F01.24
ICD-10 Finland
Subcortical vascular dementia other additional symptoms of mixed type
626.1
118.9
116
*
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
116.2
110
*
SPAT1053
SPAT
Memory test
3.6
112.3
512
1883
R53
ICD-10 Finland
Malaise and fatigue
3.4
112.0
640
2710
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.0
91.6
793
4139
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
9.6
85.5
103
114
R41.0
ICD-10 Finland
Disorientation, unspecified
6.0
82.3
154
280
F01.23
ICD-10 Finland
Subcortical vascular dementia other additional symptoms, mainly depression
732.3
71.7
70
*
F05.1
ICD-10 Finland
Delirium superimposed on dementia
98.7
68.6
75
8
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.3
68.2
311
1107
N05AH03
ATC
olanzapine; systemic
6.6
66.6
111
179
AA1AD
NOMESCO Finland
CT of head and brain
2.5
65.4
699
3867
F05.9
ICD-10 Finland
Delirium, unspecified
6.1
61.8
111
193
F01.21
ICD-10 Finland
Subcortical vascular dementia without additional symptoms, mainly paranoidism
+∞
60.8
58
*
N06AX26
ATC
vortioxetine; oral
5.4
59.6
122
240
F01.22
ICD-10 Finland
Subcortical vascular dementia with additional symptoms, mainly hallucinations
579.5
57.0
56
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
56.5
571
3032
F06.7
ICD-10 Finland
Mild cognitive disorder
5.0
55.3
125
268
N03AG01
ATC
valproic acid; systemic, rectal
5.3
53.1
112
226
N06AX11
ATC
mirtazapine; oral
2.4
53.1
578
3153
L28
ICPC
Limited function/disability (L)
2.4
52.4
518
2705
N05BA04
ATC
oxazepam; oral
2.4
48.8
482
2503
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
46.2
429
2161
A04
ICPC
Weakness/tiredness general
2.5
46.2
376
1785
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
45.5
281
1165
S01.0
ICD-10 Finland
Open wound of scalp
3.1
43.2
203
724
SPAT1216
SPAT
Assessment of functional ability
2.3
42.8
407
2061
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.8
41.3
240
961
N02AA05
ATC
oxycodone; systemic
2.2
41.3
469
2552
XA800
NOMESCO Finland
Neuropsychological investigation
6.6
40.3
66
104
N06AB10
ATC
escitalopram; oral
2.7
39.2
241
992
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
37.3
384
1996
N02BE01
ATC
paracetamol; systemic, rectal
2.8
37.0
1318
10909
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.6
36.6
239
1012
TAB00
NOMESCO Finland
Lumbar puncture
5.3
36.3
75
148
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.3
35.1
337
1696
AXX01
NOMESCO Finland
Memory assessment
13.5
34.9
33
25
I95.1
ICD-10 Finland
Orthostatic hypotension
3.1
33.8
149
510
WYA20
NOMESCO Finland
Home visit
5.1
33.8
73
150
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
33.5
32
*
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
42.1
33.2
41
10
N30.0
ICD-10 Finland
Acute cystitis
2.2
32.1
331
1709
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.6
32.0
205
857
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.1
31.3
139
477
S06.0
ICD-10 Finland
Concussion
2.6
31.3
207
879
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.0
31.1
148
529
F01
ICD-10 Finland
Vascular dementia
31.6
30.5
40
13
A29
ICPC
General symptom/complaint other
2.2
30.0
291
1463
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.0
29.8
138
485
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
29.6
631
4194
F21, ,
ICPC
6.6
29.1
47
73
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
28.9
1146
9250
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.4
28.6
232
1079
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
6.3
28.5
48
78
R42
ICD-10 Finland
Dizziness and giddiness
1.9
28.1
481
2967
S72.0
ICD-10 Finland
Fracture of neck of femur
2.8
27.8
151
579
G30
ICD-10 Finland
Alzheimer disease
102.0
27.7
30
*
SPAT1254
SPAT
Administration of medicine
2.1
26.9
330
1810
N06AB06
ATC
sertraline; oral
2.9
26.4
128
461
R55
ICD-10 Finland
Syncope and collapse
2.1
25.5
271
1404
R1250
NOMESCO Finland
Evaluation of functional capability
5.1
24.7
53
108
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
254.2
24.7
25
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.4
24.4
192
878
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
23.7
316
1776
A06AD11
ATC
lactulose; oral
1.9
23.5
388
2342
Z02.7
ICD-10 Finland
Issue of medical certificate
2.6
23.4
150
624
W19
ICD-10 Finland
Unspecified fall
2.3
23.0
200
954
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
23.0
133
526
N27
ICPC
Fear of neurological disease other
4.8
22.5
51
109
U04
ICPC
Incontinence urine
2.5
22.1
155
673
J01DB01
ATC
cefalexin; oral
1.8
22.0
1110
9174
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
81.4
21.7
24
*
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
223.1
21.6
22
*
F01.0
ICD-10 Finland
Vascular dementia of acute onset
223.1
21.6
22
*
A98
ICPC
Health maint/preventive medicine
1.9
21.2
1212
10333
N06AB04
ATC
citalopram; systemic
1.9
21.2
306
1761
R4110
NOMESCO Finland
Physiotherapy
1.8
21.1
448
2907
G04BD12
ATC
mirabegron; oral
2.0
20.8
246
1320
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
20.3
332
1988
SPAT1301
SPAT
No procedures
1.7
20.2
520
3552
AA1AD, ,
SPAT
7.1
20.0
30
43
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
19.8
296
1720
G30.0
ICD-10 Finland
Alzheimer disease with early onset
202.6
19.6
20
*
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.8
19.6
99
365
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.7
19.5
36
64
OAB76
NOMESCO Finland
General guidance on nutrition and food
46.7
19.2
23
5
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.9
19.2
95
346
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.7
18.9
61
171
A01
ICPC
Pain general/multiple sites
2.1
18.8
186
932
OAB41
NOMESCO Finland
Guidance and counselling related to ageing
17.4
18.7
29
17
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.3
18.7
49
118
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
18.6
101
386
OAB48
NOMESCO Finland
Lifestyle advice and guidance
44.6
18.3
22
5
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
18.1
252
1426
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
17.7
131
581
R44.3
ICD-10 Finland
Hallucinations, unspecified
7.5
17.4
25
34
Z2445
NOMESCO Finland
Psychologist
5.1
17.2
36
72
N30.9
ICD-10 Finland
Cystitis, unspecified
2.3
16.7
140
656
R44.1
ICD-10 Finland
Visual hallucinations
7.4
16.6
24
33
C10AA01
ATC
simvastatin; oral
1.6
16.5
836
6654
P99
ICPC
Psychological disorders other
5.3
16.3
33
64
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.7
16.3
87
330
Z75.5
ICD-10 Finland
Holiday relief care
5.1
16.2
34
68
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
+∞
15.6
15
*
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
86.0
15.6
17
*
N05AD01
ATC
haloperidol; systemic
3.0
15.5
69
237
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.0
15.3
67
228
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
7.1
15.3
23
33
R5110, ,
SPAT
2.0
15.2
178
948
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
3.9
14.8
43
112
WYA20, ,
SPAT
5.5
14.5
28
52
130
Kela drug reimbursment
Malignant tumour
0.3
14.5
36
1211
S70.0
ICD-10 Finland
Contusion of hip
2.5
14.5
93
387
P29
ICPC
Psychological sympt/compl other
3.3
14.3
54
168
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.0
14.3
173
931
AXX01, ,
SPAT
2.6
14.2
83
330
ZXA05
NOMESCO Finland
Left side
1.6
14.1
440
3099
N05AX12
ATC
aripiprazole; systemic
6.1
13.9
24
40
F22.0
ICD-10 Finland
Delusional disorder
5.1
13.9
29
58
N17
ICPC
Vertigo/dizziness
1.8
13.7
244
1483
C08CA01
ATC
amlodipine; oral
1.5
13.7
713
5617
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
13.7
226
1344
N06AX21
ATC
duloxetine; oral
2.1
13.6
142
724
F0019, G301,
ICD-10 Finland
+∞
13.6
13
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
13.5
716
5657
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.0
13.5
59
201
Z71.8
ICD-10 Finland
Other specified counselling
1.6
13.3
403
2815
Z3226
NOMESCO Finland
Physiotherapist
1.7
13.1
291
1880
SPAT1360
SPAT
Extensive global examination
2.2
13.1
118
569
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.5
13.0
85
357
SPAT1304
SPAT
Counselling and guidance related to ageing
1.8
12.8
196
1138
Z2221
NOMESCO Finland
Medical doctor
1.6
12.7
392
2742
F01.8
ICD-10 Finland
Other vascular dementia
131.1
12.5
13
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.1
12.4
114
553
SPAT1101
SPAT
Orthostatic test
2.2
12.4
110
527
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
12.3
787
6415
EBA00
NOMESCO Finland
Extraction of tooth
1.6
12.2
400
2833
SPAT1229
SPAT
Assessment of need for aid
1.9
12.1
164
916
ZXD35
NOMESCO Finland
Usual procedure
2.7
11.9
64
244
R32
ICD-10 Finland
Unspecified urinary incontinence
2.7
11.8
64
245
R33
ICD-10 Finland
Retention of urine
1.8
11.7
195
1160
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.7
11.7
36
98
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
11.7
709
5695
N05BA06
ATC
lorazepam; systemic, sublingual
2.2
11.6
98
460
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
11.5
392
2796
F009, G309,
ICD-10 Finland
+∞
11.5
11
*
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
11.5
11
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.9
11.4
33
86
S01
ICD-10 Finland
Open wound of head
4.3
11.3
29
69
C07AB07
ATC
bisoprolol; oral
1.5
11.3
908
7678
WX212
NOMESCO Finland
Femoral plexus blockade
2.6
11.3
63
245
G04CA02
ATC
tamsulosin; oral
1.5
11.2
476
3555
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.3
11.1
42
131
SPAT1139
SPAT
Nutrition survey
2.5
11.1
68
277
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.6
11.0
293
1974
E86
ICD-10 Finland
Volume depletion
2.6
10.9
64
255
B01AC04
ATC
clopidogrel; oral
1.5
10.9
359
2538
ZXA00
NOMESCO Finland
Right side
1.5
10.9
443
3277
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.2
10.9
91
426
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.8
619
4893
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
15.6
10.8
17
11
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
10.8
52
187
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
8.9
10.8
22
25
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
10.8
357
2527
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
10.7
293
1985
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.5
10.7
67
276
A10AB05
ATC
insulin aspart; parenteral
1.9
10.7
129
693
J01CA08
ATC
pivmecillinam; oral
1.5
10.6
533
4109
Y94.0
ICD-10 Finland
Accident at home
3.0
10.5
46
157
F01.1
ICD-10 Finland
Multi-infarct dementia
+∞
10.4
10
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.4
10.4
68
286
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
10.4
234
1511
F00
ICD-10 Finland
Dementia in Alzheimer disease
32.8
10.3
13
*
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
10.3
115
601
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.8
10.2
148
843
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.4
10.2
71
307
M79.6
ICD-10 Finland
Pain in limb
1.5
10.2
527
4078
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
8.0
10.1
22
28
U13
ICPC
Bladder symptom/complaint other
2.6
10.1
60
241
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.7
10.0
31
85
XQ855, ,
SPAT
4.1
10.0
27
67
C09AA05
ATC
ramipril; oral
1.5
9.9
498
3824
A10BH05
ATC
linagliptin; oral
1.9
9.9
119
637
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.7
9.8
202
1272
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
9.8
233
1522
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.6
9.8
57
227
A27
ICPC
Fear of other disease NOS
2.1
9.7
88
425
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.1
9.7
5
376
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
4.2
9.7
25
60
K08.3
ICD-10 Finland
Retained dental root
1.9
9.6
116
622
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.3
9.6
36
112
G04CB01
ATC
finasteride; oral
1.6
9.6
259
1746
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.1
9.6
20
40
A10AE04
ATC
insulin glargine; parenteral
1.8
9.5
161
960
SPAT1234
SPAT
Support of social functional capacity
2.0
9.5
107
561
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
9.5
181
1117
C10AA05
ATC
atorvastatin; oral
1.4
9.5
671
5472
SPAT1336
SPAT
Request for examination
2.3
9.4
71
318
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.4
458
3489
F01.39
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without information on additional symptoms
100.7
9.4
10
*
F01.34
ICD-10 Finland
Mixed cortical and subcortical vascular dementia are other mixed symptoms of mixed type
100.7
9.4
10
*
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
9.4
147
2392
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
5.2
9.4
19
37
U05
ICPC
Urination problems other
2.0
9.4
106
557
IGY02
NOMESCO Finland
Psychiatric monitoring contact
4.5
9.3
22
49
J01CA04
ATC
amoxicillin; systemic
1.4
9.2
999
8753
G72.8
ICD-10 Finland
Other specified myopathies
2.9
9.2
42
147
Z3231
NOMESCO Finland
Registered nurse
1.5
9.1
409
3066
E0000UV, ,
ATC
1.4
9.1
517
4050
WX110, ,
SPAT
2.5
9.0
58
242
L17
ICPC
Foot/toe symptom/complaint
1.5
9.0
401
3000
Z51.5
ICD-10 Finland
Palliative care
1.6
8.9
206
1338
N06AX16
ATC
venlafaxine; oral
1.9
8.8
111
605
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
3.5
8.8
30
88
C03CA01
ATC
furosemide; systemic
1.4
8.7
788
6664
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
8.5
398
3001
P03
ICPC
Feeling depressed
2.3
8.5
61
268
S22.3
ICD-10 Finland
Fracture of rib
1.9
8.5
111
612
F01.80
ICD-10 Finland
Other specified vascular dementia without additional symptoms
27.7
8.5
11
*
Z01.9
ICD-10 Finland
Special examination, unspecified
2.1
8.5
83
414
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.5
8.4
51
207
F0014, G301,
ICD-10 Finland
90.6
8.4
9
*
N28
ICPC
Limited function/disability (N)
3.2
8.4
33
106
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.5
8.4
53
220
KMAK, ,
NOMESCO Finland
1.4
8.4
473
3689
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.9
8.4
18
37
A99
ICPC
Disease/condition unspecnature/site
1.7
8.4
155
949
W06
ICD-10 Finland
Fall involving bed
3.8
8.4
25
67
SPAT1255
SPAT
Intravenous administration of medicine
1.9
8.4
112
623
N30
ICD-10 Finland
Cystitis
1.9
8.3
108
594
F01.89
ICD-10 Finland
Other specified vascular dementia without information on additional symptoms
+∞
8.3
8
*
F01.84
ICD-10 Finland
Other specified vascular dementia other mixed symptoms of mixed type
+∞
8.3
8
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
8.3
345
2541
EBA00, ,
SPAT
2.9
8.3
38
134
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
8.3
59
259
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.2
8.1
6
352
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
8.1
224
1514
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
3.4
8.1
28
83
S32.8
ICD-10 Finland
Fracture of other and unspecified parts of lumbar spine and pelvis
3.3
8.1
30
93
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.1
211
1408
K02.1
ICD-10 Finland
Caries of dentine
1.4
8.1
527
4208
A02BC02
ATC
pantoprazole; systemic
1.4
8.0
939
8229
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
8.0
127
743
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
8.0
118
676
P76
ICPC
Depressive disorder
2.7
8.0
42
159
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
8.0
355
2648
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
3.3
8.0
29
89
R54
ICD-10 Finland
Senility
4.3
7.9
20
47
ZXE00
NOMESCO Finland
One hour or less
1.4
7.9
518
4138
G20
ICD-10 Finland
Parkinson disease
2.3
7.8
59
265
S01.8
ICD-10 Finland
Open wound of other parts of head
3.2
7.8
30
95
E000001, ,
ATC
1.5
7.8
243
1686
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
7.8
432
3349
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.4
7.8
51
215
K43
ICPC
Cardiovascular, Other diagnostic procedure
3.1
7.8
32
106
Z2446
NOMESCO Finland
Social worker
1.9
7.8
93
499
U02
ICPC
Urinary frequency/urgency
1.6
7.7
211
1422
S20.2
ICD-10 Finland
Contusion of thorax
2.1
7.7
76
380
SPAT1252
SPAT
Overall medication plan or its review
1.8
7.7
127
752
EBA30
NOMESCO Finland
Extraction of root of tooth
2.0
7.7
87
457
L14
ICPC
Leg/thigh symptom/complaint
1.8
7.7
125
737
E53.8
ICD-10 Finland
Deficiency of other specified B group vitamins
4.4
7.7
19
44
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
7.7
374
2834
T89
ICPC
Diabetes insulin dependent
2.7
7.7
41
157
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
7.6
44
175
D07AA02
ATC
hydrocortisone; topical
1.6
7.6
168
1076
N03AF02
ATC
oxcarbazepine; oral
2.7
7.6
40
152
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
25.1
7.6
10
*
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
2.2
7.5
58
264
A10BA02
ATC
metformin; oral
1.4
7.5
468
3702
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
6.0
7.4
19
32
T90
ICPC
Diabetes non-insulin dependent
1.4
7.4
367
2789
D09
ICPC
Nausea
2.3
7.3
53
234
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.1
7.3
67
327
R06AE07
ATC
cetirizine; oral
1.4
7.3
450
3549
G04BD07
ATC
tolterodine; oral
1.8
7.3
106
606
I95.2
ICD-10 Finland
Hypotension due to drugs
3.7
7.2
22
60
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.2
600
4958
A60
ICPC
General and Unspecified, Result test/procedure
2.0
7.2
73
370
M54.5
ICD-10 Finland
Low back pain
1.4
7.1
406
3155
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
7.1
429
3365
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
20.1
7.1
10
5
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.0
7.1
71
357
D12
ICPC
Constipation
2.0
7.1
72
364
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.3
7.1
26
80
SPAT1262
SPAT
Handing over of treatment supplies
1.5
7.0
258
1851
S23.4
ICD-10 Finland
Sprain and strain of ribs and sternum
3.4
7.0
24
71
A08
ICPC
Swelling
1.8
7.0
113
667
ICB01, ,
SPAT
7.6
6.9
15
20
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
13.8
6.9
11
8
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.2
6.9
53
241
N03AX09
ATC
lamotrigine; oral
3.0
6.9
30
103
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
6.8
490
3948
G04BD08
ATC
solifenacin; oral
1.7
6.8
119
717
H3600, E113,
ICD-10 Finland
2.9
6.8
31
109
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.5
6.8
198
1353
A13
ICPC
Concern/fear medical treatment
2.5
6.8
40
161
C09CA01
ATC
losartan; oral
1.4
6.8
405
3169
H04AA01
ATC
glucagon; nasal, parenteral
4.3
6.8
17
40
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.2
6.8
53
243
H02AB02
ATC
dexamethasone; systemic
0.5
6.7
50
1029
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.0
6.7
73
379
ZXD20
NOMESCO Finland
Day surgery
1.6
6.7
160
1045
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.5
6.7
189
1283
SPAT1240
SPAT
Therapeutic discussion
2.0
6.7
68
345
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
6.7
636
5345
S20
ICPC
Corn/callosity
2.6
6.6
38
151
R11
ICD-10 Finland
Nausea and vomiting
1.6
6.6
137
865
XF600, ,
SPAT
2.1
6.6
62
306
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.4
6.6
23
69
G21.8
ICD-10 Finland
Other secondary parkinsonism
10.1
6.5
12
12
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
2.1
6.5
58
280
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
6.5
329
2502
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.8
6.5
97
559
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
6.5
148
956
N06AX12
ATC
bupropion; oral
2.7
6.4
32
119
K91
ICPC
Cerebrovascular disease
2.8
6.3
30
108
XQ858, ,
SPAT
5.2
6.3
18
35
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.0
6.3
64
325
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
9.3
6.3
12
13
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.2
6.3
52
244
IHZ08
NOMESCO Finland
Provision of support and information for patient’s relatives
18.1
6.3
9
5
F0011, G301,
ICD-10 Finland
+∞
6.3
6
*
F00, F03,
ICD-10 Finland
+∞
6.3
6
*
B01AB05
ATC
enoxaparin; parenteral
1.3
6.2
445
3574
D21
ICPC
Swallowing problem
2.8
6.2
30
109
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
7.1
6.2
14
20
Z02.8
ICD-10 Finland
Other examinations for administrative purposes
6.3
6.2
15
24
R51.80
ICD-10 Finland
Headache
1.6
6.1
147
962
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.0
6.1
25
83
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.1
427
3419
SPAT1307
SPAT
Psychosocial counselling and guidance
2.6
6.1
33
128
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
6.1
530
4382
GD1QA, ,
SPAT
10.1
6.0
11
11
J01EA01
ATC
trimethoprim; systemic
1.4
6.0
400
3175
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.7
6.0
113
695
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
6.0
290
2185

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
989
5961
2.96
84.86
3.0
2.4
90.57
94.37
pmol/l
1.98
608
3113
765
4214
2.67
75.06
2.1
1.8
18.17
19.95
nmol/l
2.60
722
3534
580
2844
2.70
71.13
1.9
1.8
1061.70
1201.54
nmol/l
3.40
464
2110
573
2900
2.58
64.61
3.0
3.2
2.47
2.48
mmol/l
0.38
511
2535
831
5037
2.47
62.85
2.5
2.4
77.44
81.84
nmol/l
4.45
767
4354
56
43
13.49
59.05
1.1
1.0
647.83
815.58
ng/l
1.18
41
26
55
43
13.24
57.37
1.1
1.0
346.91
245.85
ng/l
1.70
44
27
794
4853
2.36
56.99
4.9
3.9
—
—
—
0
0
741
4469
2.31
53.93
2.7
3.5
2.35
2.35
mmol/l
0.26
681
3965
914
6040
2.33
53.20
4.6
5.0
34.15
33.73
g/l
1.51
858
5575
1122
8122
2.54
52.77
8.0
6.0
5265.72
2657.56
e6/l
0.37
32
146
994
6839
2.36
52.13
7.1
7.4
1.22
1.21
mmol/l
2.95
890
5830
67
85
8.21
49.70
3.6
3.4
310.32
321.92
umol/l
0.25
60
75
1064
7641
2.37
48.91
37.0
30.8
329.10
329.55
g/l
0.78
1054
7555
690
4188
2.21
47.68
3.7
4.3
7.40
7.40
ph
2.45
507
3052
722
4484
2.18
46.82
4.5
4.5
—
—
—
0
0
679
4152
2.17
45.41
2.5
2.2
305.06
223.36
u/l
0.99
646
3900
528
2922
2.25
45.37
5.4
4.9
165.62
275.79
ng/l
1.29
484
2674
880
6133
2.06
39.54
5.9
6.6
1.21
1.21
mmol/l
1.96
835
5613
1177
9227
2.31
37.97
5.9
5.5
2.05
2.13
mu/l
0.91
1116
8220
1008
7444
2.09
37.89
5.7
5.2
7.13
6.94
mmol/l
1.29
971
7128
513
3004
2.08
36.55
4.5
3.9
0.16
0.10
0.15
19
155
1250
10137
2.44
35.87
28.5
22.8
29.88
30.01
mg/l
0.05
1168
8870
738
4950
1.97
35.56
5.9
4.5
213.92
148.45
e6/l
0.35
531
3697
415
2304
2.11
33.62
4.3
3.5
2.17
2.04
e6/l
0.13
206
1237
688
4581
1.93
33.12
4.8
3.9
92.30
88.24
e6/l
0.05
531
3616
1000
7622
1.95
31.06
4.1
4.2
15.27
15.36
pmol/l
0.49
941
6733
710
4874
1.87
30.24
5.1
4.2
6.30
6.34
ph
0.38
363
2607
1262
10514
2.30
30.01
35.3
28.8
139.27
139.23
mmol/l
0.18
1247
10278
1262
10519
2.30
29.89
35.6
29.0
4.00
4.03
mmol/l
3.75
1246
10272
839
6105
1.86
29.34
5.9
4.8
0.00
3.08
estimate
1.08
143
1470
840
6129
1.85
28.96
6.0
4.8
0.08
0.01
estimate
0.87
132
1382
603
3974
1.87
28.82
4.5
3.8
0.72
0.56
e6/l
0.63
451
3063
1262
10565
2.27
28.81
39.9
34.1
92.25
92.12
fl
0.46
1244
10366
1262
10565
2.27
28.81
40.0
34.2
4.20
4.27
e12/l
5.29
1225
10222
1262
10565
2.27
28.81
39.9
34.1
30.43
30.40
pg
0.16
1245
10366
1262
10565
2.27
28.81
40.0
34.2
236.63
234.76
e9/l
0.45
1231
10269
1262
10565
2.27
28.81
40.7
34.7
37.91
38.38
%
2.19
1246
10362
1262
10566
2.27
28.78
40.2
34.5
126.08
128.40
g/l
6.50
1249
10383
1261
10555
2.26
28.77
36.7
31.2
87.64
89.94
umol/l
1.15
1243
10361
1262
10569
2.26
28.71
40.0
34.2
7.44
7.16
e9/l
2.11
1229
10221
420
2481
1.96
27.85
4.3
3.4
1.21
1.39
e6/l
0.33
214
1415
1100
8808
1.95
27.61
7.0
8.4
81.10
85.69
u/l
1.77
1059
8265
609
4082
1.83
27.14
2.6
2.5
2.78
3.13
mg/l
2.01
542
3506
818
6017
1.80
26.49
5.9
4.8
0.01
0.00
estimate
0.43
141
1408
1225
10348
2.03
24.04
12.5
13.5
21.12
23.19
u/l
3.70
1193
9921
63
152
4.28
23.96
1.2
1.2
4.19
3.83
mmol/l
1.23
58
140
58
134
4.46
23.31
1.2
1.2
—
—
—
0
0
987
7830
1.77
23.15
35.8
28.7
14.22
14.22
%
0.02
978
7703
895
6917
1.74
22.92
22.9
23.6
1.45
1.44
inr
0.03
774
5908
62
155
4.13
22.51
1.5
1.3
195.66
171.73
e6/l
0.06
47
122
61
151
4.17
22.44
1.4
1.3
2.80
68.91
e6/l
0.96
44
114
66
176
3.88
21.95
1.3
1.3
582.02
636.11
mg/l
0.36
61
169
780
5891
1.68
20.96
3.2
3.2
52.34
59.92
u/l
1.34
726
5316
274
1555
1.93
19.66
4.0
3.5
292.96
310.14
ng/l
0.22
262
1432
1171
10037
1.78
18.06
23.9
20.8
—
—
—
0
0
288
1704
1.86
18.05
3.5
3.6
1.77
1.91
mmol/l
0.26
253
1430
832
6554
1.61
17.62
6.3
8.7
4.85
4.46
e9/l
3.52
677
5600
434
2950
1.66
16.53
3.6
3.3
546.31
517.92
mosm/kgh2o
2.19
381
2582
290
1765
1.80
16.44
3.6
3.6
5.81
5.82
kpa
0.09
281
1712
397
2649
1.68
16.18
6.3
5.1
1.05
1.02
kg/l
0.50
292
1833
288
1760
1.79
16.07
3.6
3.6
7.38
7.38
ph
0.65
181
1090
1126
9692
1.66
15.41
5.5
6.1
6.31
6.18
mmol/l
2.00
1054
8554
93
377
2.56
15.27
1.6
2.4
55.84
56.91
%
0.16
86
360
468
3295
1.61
15.26
3.3
2.9
5.90
5.01
e6/l
0.93
427
3000
249
1480
1.82
15.18
3.1
3.0
4.23
4.39
kpa
0.88
240
1433
823
6611
1.55
14.92
4.6
6.3
12.38
13.21
umol/l
0.77
792
6289
658
5086
1.53
13.88
3.4
3.3
123.22
154.65
ug/l
4.45
621
4604
230
1372
1.80
13.77
5.8
7.4
—
—
—
0
0
1101
9526
1.60
13.68
7.9
7.9
42.55
41.16
mmol/mol
3.64
1043
8642
700
5506
1.51
13.46
5.2
6.0
23.52
24.23
%
0.81
660
5166
1111
9691
1.57
12.74
5.8
6.4
2.25
2.37
mmol/l
5.62
1053
8630
729
5826
1.49
12.71
4.9
5.5
0.04
0.04
e9/l
0.16
589
4861
725
5801
1.49
12.48
4.9
5.5
0.67
0.64
e9/l
1.71
586
4825
389
2729
1.58
12.45
2.4
2.7
10.23
11.16
umol/l
2.12
360
2521
681
5384
1.49
12.43
5.0
5.8
60.71
60.09
%
0.64
652
5108
370
2574
1.58
12.25
2.3
2.7
2.20
2.21
g/l
0.21
343
2356
739
5960
1.48
12.08
5.1
5.7
0.21
0.20
e9/l
1.45
603
5050
733
5917
1.47
11.84
5.0
5.7
1.85
1.79
e9/l
0.28
592
5059
683
5447
1.47
11.69
5.0
5.9
9.02
9.28
%
1.44
646
5063
682
5438
1.47
11.68
5.0
5.9
0.59
0.61
%
0.58
645
5061
166
943
1.86
11.58
3.0
3.5
24.17
24.15
mmol/l
0.02
161
927
436
3185
1.52
11.48
4.0
4.3
76.92
79.42
%
1.29
425
3114
64
249
2.64
11.46
2.0
2.1
29.43
34.13
umol/l
0.62
51
218
93
430
2.24
11.44
3.9
5.4
1.25
1.35
mmol/l
0.62
88
384
680
5440
1.46
11.33
5.0
5.8
2.82
2.76
%
0.29
641
5053
406
2932
1.53
11.24
1.9
1.8
442.33
8326668.65
pmol/l
1.06
357
2342
27
62
4.42
11.00
1.4
1.2
—
—
—
0
0
328
2275
1.57
10.84
1.7
1.9
29.64
30.15
s
0.68
321
2201
153
879
1.83
10.28
2.4
2.6
1.05
1.11
%
0.50
153
874
507
3895
1.46
10.14
2.4
2.5
56.12
62.22
u/l
1.48
477
3572
150
865
1.82
9.95
2.4
2.6
0.61
0.63
%
0.30
150
860
62
259
2.45
9.63
1.2
1.2
—
—
—
0
0
451
3416
1.46
9.62
5.8
6.6
—
—
—
0
0
445
3374
1.45
9.40
3.0
3.0
30.94
36.53
u/l
2.69
418
3144
522
4087
1.43
9.23
4.4
5.5
—
—
—
0
0
106
564
1.95
9.03
1.8
2.1
1060.56
669.34
ug/l
0.34
97
534
190
1213
1.65
8.75
3.2
3.8
89.42
105.51
ng/l
2.31
163
1007
333
2415
1.49
8.74
2.4
2.8
19.34
20.47
%
1.04
310
2229
556
4448
1.40
8.53
6.7
5.0
0.20
0.94
estimate
0.64
97
1154
269
1882
1.52
8.36
5.4
6.3
1.49
1.04
mmol/l
1.02
221
1508
269
1889
1.52
8.21
5.5
6.3
7.42
7.41
ph
0.74
160
1059
1051
9405
1.40
7.79
4.7
5.4
4.10
4.24
mmol/l
4.66
979
8426
208
1397
1.57
7.75
2.3
2.6
10.67
10.72
umol/l
0.01
177
1218
292
2111
1.48
7.70
2.1
2.4
1.79
1.81
%
0.17
259
1875
540
4358
1.37
7.65
5.2
6.6
2.56
5.81
ug/l
2.51
492
3837
315
2325
1.45
7.44
2.1
2.8
0.81
0.82
mmol/l
0.32
284
2152
265
1892
1.49
7.42
5.5
6.3
4.96
5.09
kpa
1.32
253
1799
265
1893
1.49
7.39
5.5
6.3
10.87
11.53
kpa
1.36
253
1802
1038
9304
1.38
7.36
4.5
5.3
1.41
1.43
mmol/l
1.01
965
8230
179
1183
1.58
7.13
2.9
2.5
35.14
37.58
u/l
0.21
151
978
392
3031
1.40
7.10
6.3
4.4
0.07
0.07
estimate
0.03
94
1075
641
5379
1.34
6.83
5.2
5.0
41.27
70.30
ng/l
1.70
510
4494
22
63
3.53
6.72
3.1
1.6
1.50
2.54
u/field
0.46
16
39
25
78
3.24
6.71
1.3
1.1
—
—
—
0
0
109
654
1.72
6.35
2.2
2.2
—
—
—
0
0
152
997
1.58
6.26
4.9
5.9
24.74
24.35
mmol/l
0.59
147
954
33
130
2.57
5.89
1.6
1.4
10.56
9.66
%
0.52
33
130
642
5467
1.31
5.88
3.3
3.7
2079.09
2356.04
ng/l
0.86
573
4878
57
1068
0.52
5.82
1.3
1.4
—
—
—
0
0
229
1676
1.43
5.56
5.9
6.5
94.57
95.13
%
0.40
220
1612
321
2489
1.37
5.56
1.7
1.6
1.43
1.68
mg/l
0.90
278
1973
11
13
8.51
5.56
5.9
1.6
0.36
0.69
u/field
0.53
11
13
200
1430
1.46
5.50
2.6
2.6
4.60
5.93
ug/l
1.26
169
1226
499
4156
1.30
5.24
2.4
2.8
—
—
—
0
0
207
1541
1.40
4.55
1.8
1.8
—
—
—
0
0
975
8942
1.26
4.30
4.1
4.5
1.24
1.23
mmol/l
0.21
887
7803
29
126
2.33
4.28
1.2
1.1
30.58
34.68
mmol/l
0.52
23
109
629
5501
1.25
4.20
2.7
3.1
—
—
estimate
—
0
0
14
41
3.44
4.19
1.2
1.1
36.44
48.43
mg/l
0.51
14
32
61
353
1.76
4.12
1.3
1.3
61.96
59.10
mmol/l
0.28
52
283
69
420
1.67
3.91
4.0
3.7
1.90
1.64
index
0.12
37
221
12
30
4.02
3.59
2.5
2.9
27.57
27.71
umol/l
—
7
23
67
416
1.64
3.55
5.0
3.7
8.02
7.95
mmol/l
0.07
67
407
16
57
2.83
3.53
1.1
1.0
127.19
133.62
nmol/l
0.24
16
57
134
972
1.42
3.45
5.3
3.4
6.14
6.08
ph
0.35
101
728
140
1032
1.39
3.29
1.8
2.0
392.08
402.75
nmol/l
0.27
132
927
197
2495
0.76
3.27
4.4
3.9
—
—
—
0
0
123
892
1.41
3.18
1.6
1.7
1.53
1.54
g/l
0.03
106
779
13
40
3.27
3.14
1.2
1.1
281.08
281.30
mg/l
0.00
13
33
555
4907
1.21
3.08
11.1
13.5
0.00
0.00
e9/l
0.85
402
3952
36
199
1.83
2.91
1.1
1.2
—
—
—
0
0
380
4386
0.82
2.80
2.1
2.5
—
—
—
0
0
169
1318
1.32
2.79
1.6
2.0
0.19
0.19
g/l
0.64
156
1196
21
97
2.18
2.77
1.5
1.2
—
—
—
0
0
404
3498
1.21
2.73
6.3
4.8
0.00
0.00
estimate
0.78
111
1225
94
671
1.43
2.69
1.2
1.2
—
—
—
0
0
41
243
1.71
2.65
1.6
1.5
0.17
0.29
mg/l
1.22
17
91
21
99
2.14
2.65
1.7
1.6
104.19
107.71
ng/l
0.09
21
99
13
49
2.67
2.62
1.4
1.4
87.38
80.03
umol/l
—
8
33
203
1639
1.28
2.59
2.4
2.4
72.05
67.01
e9/l
0.80
150
1224
7
16
4.39
2.47
2.0
1.1
—
—
—
0
0
71
490
1.47
2.45
5.0
3.5
1.55
1.73
mmol/l
1.24
71
479
16
70
2.30
2.41
2.3
1.8
109.94
99.54
umol/l
0.25
16
70
69
477
1.47
2.37
7.4
4.9
—
—
—
0
0
6
13
4.63
2.27
2.2
1.2
—
—
—
0
0
244
2048
1.23
2.23
4.5
5.2
1.03
1.05
mmol/l
0.55
222
1894
89
656
1.38
2.17
3.3
2.3
10.28
10.73
g/l
0.44
79
568
27
153
1.78
2.08
2.4
2.2
1.95
1.64
u/field
0.17
20
70
70
500
1.42
2.06
2.7
2.8
4.27
4.27
pmol/l
0.01
60
435
7
20
3.51
2.05
2.0
1.2
—
—
—
0
0
7
20
3.51
2.05
2.0
1.2
—
—
—
0
0
7
20
3.51
2.05
2.0
1.2
—
—
—
0
0
7
20
3.51
2.05
2.0
1.2
—
—
—
0
0
360
3163
1.18
2.02
2.4
2.6
—
—
—
0
0
57
394
1.46
2.00
1.6
2.3
124.43
123.95
g/l
0.06
49
298
7
21
3.34
1.96
2.0
1.1
—
—
—
0
0
6
16
3.76
1.93
1.3
1.4
—
—
—
0
0
106
824
1.31
1.86
6.6
4.2
1.02
1.02
ratio
0.80
96
749
123
977
1.28
1.84
7.1
7.7
24.50
24.36
mmol/l
0.17
117
940
26
152
1.72
1.84
1.2
1.3
271.35
269.88
mosm/kgh2o
0.10
17
115
103
800
1.31
1.82
2.7
2.6
—
—
—
0
0
230
1961
1.20
1.81
2.1
2.0
—
—
—
0
0
28
168
1.68
1.81
1.7
2.1
0.77
1.39
g/24h
—
10
95
179
1491
1.23
1.78
4.6
5.9
10.85
12.64
mmol/l
2.59
167
1414
31
193
1.62
1.75
1.3
1.2
0.79
0.82
nmol/l
0.07
25
158
75
561
1.35
1.72
2.3
3.3
25.48
25.26
mmol/l
0.19
75
553
42
283
1.50
1.70
1.1
1.2
—
—
—
0
0
35
525
0.66
1.67
4.2
4.2
24.91
24.86
mmol/l
0.04
30
476
7
164
0.42
1.66
1.4
1.4
82.43
409.02
pmol/l
—
7
159
35
229
1.54
1.63
1.7
1.3
—
—
—
0
0
111
888
1.27
1.60
1.4
1.4
—
—
—
0
0
54
390
1.40
1.55
1.4
1.5
—
—
—
0
0
52
712
0.72
1.54
3.7
3.9
—
—
—
0
0
11
218
0.50
1.51
2.5
2.8
—
—
—
0
0
32
210
1.54
1.49
1.6
1.6
3.34
3.63
iu/l
—
8
82
41
574
0.71
1.40
1.2
1.2
—
—
—
0
0
0
40
0.00
1.32
0.0
1.2
—
9.15
—
0
34
42
300
1.41
1.32
4.5
4.0
31.06
32.35
mg/l
0.07
31
228
7
147
0.47
1.32
1.1
1.8
65.86
48.24
nmol/l
—
7
137
15
83
1.82
1.31
2.5
2.5
—
—
—
0
0
76
598
1.29
1.29
3.1
3.1
1.45
6.90
ratio
2.02
49
354
13
229
0.56
1.26
1.0
1.4
—
—
—
0
0
121
1443
0.82
1.25
1.2
1.3
9.90
15.30
u/ml
0.31
27
459
5
116
0.43
1.25
1.2
1.8
—
—
—
0
0
91
1115
0.80
1.23
2.9
4.1
0.00
0.11
%
6.54
27
350
170
1469
1.18
1.20
2.8
2.6
65.67
65.49
g/l
0.11
150
1317
141
1200
1.19
1.18
2.9
2.4
—
—
—
0
0
24
157
1.54
1.17
2.8
3.6
15.64
12.28
index
0.44
14
76
217
1917
1.15
1.16
1.3
1.2
3.48
1.45
u/ml
0.54
41
453
6
130
0.46
1.16
1.2
1.1
—
—
—
0
0
8
156
0.51
1.13
2.4
2.8
—
—
—
0
0
12
208
0.57
1.12
1.2
1.7
20.85
19.32
ug/l
0.11
12
202
80
648
1.25
1.10
3.1
3.2
64.79
74.92
mg/l
0.14
73
552
90
1088
0.82
1.09
2.8
4.0
0.62
0.68
%
0.14
29
364
7
32
2.19
1.08
1.1
1.4
—
—
—
0
0
80
650
1.24
1.08
3.2
3.2
48.95
154.65
mg/l
0.68
73
550
16
97
1.66
1.07
2.3
3.2
—
—
—
0
0
144
1662
0.85
1.06
2.8
3.9
8.66
26.37
ug/l
1.46
126
1416
134
1551
0.85
1.02
1.3
1.4
—
—
—
0
0
23
155
1.49
1.01
1.4
1.8
—
—
—
0
0
343
3722
0.90
0.99
1.7
1.9
1.28
1.24
mmol/l
0.52
320
3005
9
159
0.56
0.98
1.1
1.3
—
—
—
0
0
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
7
36
1.95
0.97
1.9
1.4
—
—
—
0
0
99
1166
0.84
0.94
2.8
4.1
0.69
0.89
%
0.46
35
400
63
775
0.80
0.93
1.7
1.6
—
—
—
0
0
281
2570
1.12
0.90
1.2
1.3
—
—
—
0
0
135
1180
1.16
0.87
3.0
3.9
1.24
1.22
mmol/l
2.19
122
1017
10
57
1.76
0.83
1.3
1.1
8.90
9.77
mmol/l
—
10
52
13
202
0.64
0.83
5.8
3.0
4.70
4.86
e9/l
0.09
13
202
16
236
0.67
0.80
5.0
3.2
60.48
61.90
%
0.13
16
236
9
150
0.60
0.79
2.6
4.5
—
—
—
0
0
0
26
0.00
0.78
0.0
1.4
—
76.48
—
0
21
7
125
0.56
0.77
1.0
1.2
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
159.18
—
0
27
6
34
1.77
0.76
1.3
1.2
422.50
205.89
iu/ml
—
6
34
0
28
0.00
0.76
0.0
1.3
—
0.76
—
0
10
14
91
1.54
0.75
1.3
1.5
—
—
—
0
0
136
1529
0.88
0.74
1.2
1.3
—
—
—
0
0
47
379
1.25
0.73
2.0
3.1
88.81
88.11
%
0.40
47
367
70
589
1.20
0.73
4.2
3.3
0.79
0.84
nmol/l
0.55
55
479
16
108
1.49
0.73
1.1
1.5
21.54
37.63
ng/l
0.71
16
108
55
453
1.22
0.72
1.3
1.2
—
—
—
0
0
42
336
1.26
0.71
1.7
1.5
20926.34
18186.78
e6/l
0.11
29
233
68
802
0.84
0.70
1.4
1.5
—
—
—
0
0
18
127
1.42
0.68
1.6
1.2
303.17
334.82
nmol/l
0.17
12
99
141
1569
0.89
0.67
1.2
1.3
26.11
39.12
iu/ml
0.91
40
491
96
1093
0.87
0.65
2.6
4.4
0.07
0.20
%
0.91
27
311
5
29
1.73
0.64
1.0
1.8
15.24
16.19
pmol/l
—
5
22
104
1175
0.88
0.63
1.3
1.3
—
—
—
0
0
76
655
1.17
0.63
2.6
2.9
—
—
—
0
0
114
1015
1.13
0.61
7.9
8.0
92.00
93.97
%
1.10
114
1009
31
244
1.28
0.61
1.1
1.1
195.00
81.76
titre
—
6
17
24
311
0.77
0.60
1.1
1.2
—
—
—
0
0
82
716
1.15
0.59
1.4
1.5
—
—
—
0
0
7
114
0.61
0.58
1.1
1.2
—
—
—
0
0
41
337
1.22
0.57
15.5
14.6
—
—
—
0
0
5
86
0.58
0.56
1.0
1.1
—
—
—
0
0
133
1206
1.11
0.54
2.4
2.2
0.00
0.00
estimate
-0.00
33
232
13
91
1.43
0.53
2.5
2.2
3.19
3.10
ug/l
0.03
13
85
19
249
0.76
0.53
1.6
1.5
—
—
—
0
0
51
434
1.18
0.52
2.0
3.2
7.70
7.63
kpa
0.12
51
426
23
180
1.28
0.49
1.3
1.2
—
—
—
0
0
31
253
1.23
0.48
1.1
1.2
—
741.67
—
0
6
7
47
1.49
0.47
1.9
1.5
—
—
—
0
0
468
4498
1.06
0.46
3.9
4.2
10.00
10.88
mg/mmol
0.19
334
2892
16
120
1.34
0.46
1.3
1.2
—
—
nmol/l
—
0
0
21
165
1.28
0.45
1.4
2.0
—
—
—
0
0
20
253
0.79
0.44
1.5
1.6
—
—
—
0
0
43
500
0.86
0.43
1.2
1.3
—
—
—
0
0
17
218
0.78
0.42
1.2
1.1
—
—
—
0
0
23
283
0.81
0.41
1.3
1.4
—
—
—
0
0
20
250
0.80
0.41
1.6
1.4
—
—
—
0
0
5
33
1.52
0.41
1.0
1.2
158.40
143.91
mmol/24h
—
5
33
26
213
1.22
0.41
1.2
1.3
—
10.20
—
0
5
19
150
1.27
0.40
1.0
1.2
—
—
—
0
0
7
105
0.67
0.39
1.6
1.8
16.66
15.64
%
—
7
105
184
1727
1.07
0.39
1.5
1.5
3.22
2.74
g/l
1.16
104
960
82
742
1.11
0.38
3.5
4.1
36.94
36.89
°c
0.87
82
733
92
1008
0.91
0.38
1.8
1.9
223.75
167.70
ug/g
0.75
76
776
139
1295
1.08
0.36
2.9
3.0
4.37
5.07
e9/l
1.28
122
1062
5
77
0.65
0.35
1.0
1.2
—
—
—
0
0
88
959
0.91
0.34
5.6
4.8
—
—
—
0
0
6
47
1.28
0.32
1.5
1.6
70.67
118.35
ug/l
—
6
42
52
580
0.89
0.31
1.6
2.1
0.00
0.00
estimate
-0.00
15
156
41
464
0.88
0.31
1.6
1.2
273.40
264.77
u/ml
0.02
36
422
94
1015
0.92
0.31
3.0
3.9
7.42
7.41
ph
0.23
84
858
7
53
1.32
0.31
1.1
1.0
—
—
—
0
0
7
53
1.32
0.31
1.1
1.0
—
—
—
0
0
23
269
0.85
0.27
1.4
1.4
103950.36
81075.00
e6/l
0.14
11
157
138
1303
1.07
0.27
3.9
4.8
7.33
7.36
ph
0.61
119
939
86
798
1.08
0.27
1.7
2.8
11.69
11.10
g/l
0.42
79
717
16
131
1.22
0.27
1.3
1.5
564.00
303.64
titre
—
5
11
26
299
0.87
0.26
1.5
1.4
1051.86
1509.18
e6/l
0.67
14
214
134
1269
1.06
0.25
1.4
1.5
—
—
—
0
0
19
223
0.85
0.24
1.3
1.1
—
—
—
0
0
6
82
0.73
0.24
1.0
1.1
—
—
—
0
0
41
370
1.11
0.23
2.2
4.2
—
—
—
0
0
424
4345
0.97
0.23
3.4
3.4
55.88
53.50
mg/l
0.08
312
2891
339
3294
1.04
0.23
2.8
3.2
372.13
376.38
umol/l
0.29
302
2756
19
162
1.18
0.23
1.0
1.1
—
—
—
0
0
16
134
1.20
0.23
1.0
1.1
—
—
—
0
0
262
2536
1.04
0.22
3.2
3.7
0.72
0.92
ug/l
3.12
212
1853
0
11
0.00
0.21
0.0
1.0
—
0.05
—
0
11
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
110.77
—
0
13
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
33
365
0.90
0.20
1.4
1.4
1.77
7.89
iu/ml
—
9
85
10
120
0.83
0.16
1.0
1.1
1.55
1.66
g/l
—
10
107
14
120
1.17
0.16
1.2
1.2
0.19
0.21
nmol/l
—
9
93
29
318
0.91
0.16
1.7
2.4
340.44
77.28
ug/min
0.42
14
184
15
130
1.16
0.15
1.1
1.1
—
—
—
0
0
9
81
1.11
0.15
2.3
1.4
—
—
—
0
0
116
1203
0.96
0.13
1.2
1.3
428.80
494.14
titre
0.25
25
297
8
99
0.81
0.13
2.9
2.6
34.88
33.22
mg/l
—
8
77
9
109
0.82
0.13
2.0
1.4
—
—
—
0
0
17
152
1.12
0.12
1.2
1.4
—
—
—
0
0
17
152
1.12
0.12
1.2
1.4
—
—
—
0
0
17
152
1.12
0.12
1.2
1.4
—
—
—
0
0
17
152
1.12
0.12
1.2
1.4
—
—
—
0
0
10
86
1.16
0.11
1.4
1.2
0.33
0.52
g/l
—
5
71
10
86
1.16
0.11
1.4
1.2
6.01
7.87
g/l
—
5
70
60
626
0.96
0.10
1.2
1.3
—
—
—
0
0
15
166
0.90
0.09
1.3
1.1
—
—
—
0
0
10
87
1.15
0.09
1.4
1.2
—
—
—
0
0
38
360
1.06
0.09
1.6
2.6
1.70
1.92
mg/l
0.88
30
304
13
144
0.90
0.08
1.5
2.1
509.77
775.35
mg
0.45
13
144
5
63
0.79
0.08
1.8
1.3
—
—
—
0
0
6
73
0.82
0.07
1.0
1.0
—
—
—
0
0
49
509
0.96
0.07
1.8
2.7
492.25
437.56
mg/l
0.07
16
207
36
376
0.96
0.06
1.5
1.5
225.48
251.80
ug/g
0.37
21
241
49
505
0.97
0.05
1.3
1.3
—
—
—
0
0
14
130
1.08
0.04
1.0
1.1
—
—
—
0
0
437
4343
1.01
0.04
3.3
3.4
6.53
6.50
mmol/l
0.05
393
3550
34
328
1.04
0.04
2.9
5.0
1.96
2.94
mmol/l
2.40
25
225
65
637
1.02
0.03
1.5
1.9
1.52
1.47
g/l
0.05
58
564
13
139
0.93
0.03
1.2
1.2
—
—
—
0
0
14
149
0.94
0.03
1.1
1.1
—
—
—
0
0
14
132
1.06
0.02
1.3
1.1
335.33
358.96
u/ml
—
9
70
21
218
0.96
0.02
3.4
2.3
—
—
—
0
0
12
127
0.94
0.01
1.3
1.2
179964.29
204470.55
e6/l
—
7
80
217
2176
1.00
0.00
4.4
4.8
—
—
—
0
0
15
148
1.01
0.00
1.6
1.2
—
—
—
0
0
15
152
0.99
0.00
1.8
2.3
0.91
1.01
mmol/l
0.05
15
147
39
391
1.00
0.00
1.1
1.1
34.64
115.97
u/ml
2.57
12
126
80
801
1.00
0.00
1.3
1.5
—
—
—
0
0
57
575
0.99
0.00
2.0
3.0
47.09
8653.18
u/ml
1.09
46
493
75
745
1.01
0.00
1.6
1.8
0.99
2.18
ug/l
1.13
66
649
103
1035
0.99
0.00
3.0
3.9
5.24
5.20
kpa
0.19
98
985
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
2.06
—
0
5
0
5
0.00
0.00
0.0
4.2
—
—
—
0
0
7
70
1.00
-0.00
1.4
1.9
956.14
922.52
e6/l
—
7
65
0
7
0.00
-0.00
0.0
4.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
58
0.86
-0.00
1.6
2.0
—
—
—
0
0
11
110
1.00
-0.00
1.5
1.7
7.72
8.12
mmol/l
0.22
11
110
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
-0.00
1.4
2.3
690.20
590.73
ml
—
5
64
11
110
1.00
-0.00
1.5
1.2
—
—
—
0
0
7
77
0.91
-0.00
1.3
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
66
0.91
-0.00
1.5
1.4
1.81
3.27
mmol/l
—
6
61
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: VD_SC – Vascular dementia (subcortical)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).