Endometriosis in cutaneous scar

N14_ENDOMETRIOSIS_SKIN_SCAR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N80.6
  • Hospital discharge: ICD-9 6176
  • Cause of death: ICD-10 N80.6
  • Cause of death: ICD-9 6176

2 out of 7 registries used, show all original rules.

145

4. Check minimum number of events

None

145

5. Include endpoints

None

145

6. Filter based on genotype QC (FinnGen only)

133

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N80
Name in latin
Endometriosis cicatricis cutaneae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 700 700 -
Only index persons 683 683 -
Unadjusted period prevalence (%)
Whole population 0.02 0.02 -
Only index persons 0.03 0.03 -
Median age at first event (years)
Whole population - 36.97 -
Only index persons - 36.92 -

-FinnGen-

Key figures

All Female Male
Number of individuals 133 133 -
Unadjusted period prevalence (%) 0.05 0.05 -
Median age at first event (years) 36.96 36.96 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
137
Matched controls
1370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N80.6
ICD-10 Finland
Endometriosis in cutaneous scar
+∞
163.0
122
*
N80.9
ICD-10 Finland
Endometriosis, unspecified
489.8
38.0
36
*
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
30.3
28
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
6.5
26.6
68
181
TLC00
NOMESCO Finland
Insertion of intrauterine device
11.7
26.3
30
32
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
5.8
23.8
82
279
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
+∞
23.6
22
*
N80.0
ICD-10 Finland
Endometriosis of uterus
+∞
22.5
21
*
JAA10
NOMESCO Finland
Excision of lesion of abdominal wall
+∞
21.4
20
*
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
21.4
20
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
6.1
20.0
44
99
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
8.5
19.9
29
42
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
7.9
19.3
30
47
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
5.7
18.6
44
105
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
7.3
17.8
30
51
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
4.6
17.5
66
230
6176A
ICD-9 Finland
Endometriosis in scar of skin
+∞
17.0
16
*
N80.1
ICD-10 Finland
Endometriosis of ovary
102.9
17.0
18
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
19.1
15.9
24
15
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
+∞
15.9
15
*
N97.9
ICD-10 Finland
Female infertility, unspecified
43.7
15.8
19
5
N81.6
ICD-10 Finland
Rectocele
51.4
15.5
18
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
6.1
15.1
30
60
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
11.2
13.7
26
28
LCA06
NOMESCO Finland
Biopsy of endometrium
12.0
13.7
25
25
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
5.1
13.5
34
84
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
4.5
12.3
36
100
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
51.6
12.1
14
*
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
+∞
11.6
11
*
N84.0
ICD-10 Finland
Polyp of corpus uteri
130.5
11.6
12
*
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
130.5
11.6
12
*
N81.1
ICD-10 Finland
Cystocele
47.5
11.1
13
*
N80
ICD-10 Finland
Endometriosis
65.2
10.8
12
*
JAH01
NOMESCO Finland
Laparoscopy
10.9
10.7
20
21
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
118.7
10.6
11
*
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
+∞
10.5
10
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.2
10.5
70
334
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
5.7
10.4
21
42
B02AA02
ATC
tranexamic acid; systemic
4.3
10.2
31
88
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
22.0
10.0
14
7
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
59.3
9.8
11
*
N97.8
ICD-10 Finland
Female infertility of other origin
107.1
9.5
10
*
TLC02
NOMESCO Finland
Simple extraction of IUD
8.1
9.5
21
30
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
8.5
9.3
20
27
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.0
9.2
19
24
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
10.6
9.1
17
18
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.4
8.6
18
37
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
95.7
8.5
9
*
N80.5
ICD-10 Finland
Endometriosis of intestine
+∞
8.4
8
*
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
+∞
8.4
8
*
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
+∞
8.4
8
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
8.4
68
351
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
23.7
8.2
11
5
ULC02
NOMESCO Finland
Hysteroscopy
12.9
7.8
13
11
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
26.7
7.7
10
*
JN3AD
NOMESCO Finland
Abdominal CT examination
4.2
7.4
21
56
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
+∞
7.4
7
*
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
+∞
7.4
7
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
7.3
53
255
R2110
NOMESCO Finland
Giving the first information
4.7
7.0
17
40
N02BE01
ATC
paracetamol; systemic, rectal
4.7
6.9
128
1031
WX320
NOMESCO Finland
Spinalanesthesy
2.8
6.7
41
179
G03GA06
ATC
follitropin beta; parenteral
10.8
6.7
12
12
G03DC03
ATC
lynestrenol; oral
10.8
6.7
12
12
ZXD10
NOMESCO Finland
Scheduled procedure
2.6
6.5
55
282
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
6.9
6.4
15
24
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
19.1
6.4
9
5
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
3.3
6.3
26
90
N97.0
ICD-10 Finland
Female infertility associated with anovulation
+∞
6.3
6
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
7.3
6.2
14
21
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
6.1
36
153

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
39
115
4.34
12.37
1.4
1.3
—
—
—
0
0
78
417
3.02
9.25
2.1
1.8
—
—
—
0
0
19
52
4.08
6.46
2.6
3.8
26.21
60.82
u/ml
0.39
19
52
86
546
2.54
6.45
2.7
2.4
—
—
estimate
—
0
0
58
335
2.27
5.05
2.4
1.9
—
—
—
0
0
12
20
6.46
5.04
1.8
1.3
41.17
87.10
pmol/l
0.82
12
20
63
382
2.20
4.83
4.9
4.4
37.01
37.18
g/l
0.12
58
369
24
98
2.76
4.34
1.4
1.4
41.12
24.92
iu/l
0.75
19
83
101
762
2.24
4.19
5.4
3.7
—
—
—
0
0
58
356
2.09
4.18
5.6
7.4
0.98
1.08
inr
3.92
51
289
65
417
2.06
4.15
2.1
1.9
94.91
95.55
pmol/l
0.04
37
235
25
110
2.56
3.90
1.4
1.4
—
—
—
0
0
49
298
2.00
3.51
2.1
2.2
—
—
—
0
0
28
139
2.27
3.36
2.9
2.4
14.19
14.29
umol/l
0.02
28
129
131
1175
3.62
3.28
15.8
10.3
19.59
18.06
mg/l
0.25
117
901
22
100
2.43
3.20
3.2
6.6
105.18
105.16
mmol/l
0.01
22
100
43
262
1.93
3.01
2.2
1.7
0.68
0.87
mg/l
0.48
35
197
61
421
1.81
2.87
4.5
2.9
0.21
0.02
estimate
0.57
19
89
30
167
2.02
2.69
3.7
2.2
6.06
9.03
e6/l
0.69
30
150
75
562
1.74
2.58
4.7
3.1
0.00
0.00
estimate
-0.00
22
105
47
308
1.80
2.57
4.5
2.5
0.00
0.01
estimate
0.49
18
86
50
341
1.73
2.36
1.5
1.3
0.59
1.51
u/ml
0.87
18
107
63
460
1.68
2.31
3.7
2.8
6.33
6.33
ph
0.00
36
250
75
575
1.67
2.28
4.8
3.1
0.63
0.00
estimate
0.48
24
107
5
9
5.72
2.23
1.4
1.1
—
—
nmol/l
—
0
0
74
571
1.64
2.15
4.9
3.2
0.00
0.00
estimate
-0.00
20
101
5
10
5.14
2.09
2.0
1.1
0.40
0.54
nmol/l
—
5
10
5
10
5.14
2.09
2.0
1.1
—
—
—
0
0
75
584
1.63
2.08
4.3
4.1
6.34
6.46
mmol/l
0.17
67
525
11
44
2.63
2.07
5.3
1.6
1.14
1.18
g/l
0.17
11
39
14
64
2.32
2.02
2.7
3.0
—
—
—
0
0
11
45
2.57
1.98
1.6
1.3
—
—
—
0
0
21
115
1.98
1.96
1.1
1.1
—
—
—
0
0
120
1069
1.99
1.91
4.1
3.3
1.25
1.17
mmol/l
0.32
114
1010
9
34
2.76
1.90
1.0
1.1
—
—
—
0
0
43
300
1.63
1.81
1.6
1.3
2.09
2.13
g/l
0.06
31
201
7
24
3.02
1.74
1.7
1.1
—
—
—
0
0
48
352
1.56
1.62
4.4
3.1
53.35
76.30
e6/l
0.24
37
212
43
308
1.58
1.61
3.8
3.0
7.59
7.35
mmol/l
0.12
38
264
42
300
1.58
1.59
5.2
3.1
0.00
0.00
estimate
-0.00
22
105
5
15
3.42
1.53
10.6
2.3
11.34
5.40
pmol/l
—
5
15
5
15
3.42
1.53
1.0
1.5
—
—
—
0
0
21
126
1.79
1.51
1.4
1.9
28.12
29.18
s
0.34
21
121
66
527
1.49
1.47
3.1
2.6
—
—
—
0
0
14
74
1.99
1.45
1.0
1.2
—
—
—
0
0
21
128
1.76
1.43
1.2
1.2
—
—
—
0
0
41
301
1.52
1.36
2.0
2.8
11.69
28.53
ng/l
1.01
15
148
30
205
1.59
1.35
3.5
3.2
—
—
—
0
0
63
507
1.45
1.32
5.7
5.9
11.98
9.14
umol/l
1.04
56
483
71
586
1.44
1.29
8.1
6.0
1.83
2.05
e9/l
1.00
62
517
22
141
1.67
1.27
3.2
2.8
0.82
0.82
mmol/l
0.00
22
135
8
36
2.30
1.26
3.8
2.3
0.90
1.11
%
—
8
36
8
36
2.30
1.26
3.8
2.3
0.69
0.59
%
—
8
36
19
121
1.66
1.13
1.1
1.3
218.84
126.69
u/ml
—
9
56
68
567
1.40
1.12
8.3
6.2
0.04
0.04
e9/l
0.38
60
491
5
21
2.43
1.10
1.4
1.1
—
—
—
0
0
62
511
1.39
1.08
9.1
6.3
0.60
0.68
%
0.62
57
480
5
108
0.44
1.06
4.6
1.7
—
—
—
0
0
70
591
1.38
1.05
8.4
6.9
0.16
0.17
e9/l
0.32
63
518
5
22
2.32
1.04
1.6
1.6
—
—
—
0
0
5
22
2.32
1.04
1.2
1.2
—
—
—
0
0
19
124
1.62
1.03
1.6
1.7
12949.14
5140.86
u/l
—
8
49
32
236
1.46
1.02
4.2
2.7
0.13
0.32
e6/l
0.91
27
161
17
108
1.66
1.02
1.8
1.3
—
—
—
0
0
34
254
1.45
1.02
3.4
3.1
1.02
1.02
kg/l
0.21
20
163
16
100
1.68
1.02
1.4
1.4
—
—
—
0
0
14
85
1.72
0.98
1.1
1.2
—
—
—
0
0
67
566
1.36
0.98
8.4
6.1
0.50
0.52
e9/l
0.56
59
491
75
647
1.35
0.95
10.7
9.9
4.07
3.98
e9/l
0.14
65
558
6
27
2.28
0.94
1.0
5.7
36.95
37.00
°c
—
6
27
62
522
1.34
0.91
15.6
8.2
0.00
0.00
e9/l
0.62
50
419
10
56
1.85
0.90
3.7
2.6
4.22
4.51
kpa
—
10
56
39
306
1.38
0.89
1.5
1.8
—
—
—
0
0
37
288
1.39
0.89
4.2
4.3
—
—
—
0
0
6
30
2.04
0.88
1.0
1.1
—
—
—
0
0
6
30
2.04
0.88
1.0
1.1
—
—
—
0
0
131
1257
1.96
0.87
14.7
9.3
—
—
—
0
0
10
58
1.78
0.82
1.1
1.1
1.63
1.57
g/l
—
10
58
50
414
1.33
0.81
1.8
2.0
—
—
—
0
0
35
277
1.35
0.76
3.8
3.2
51.45
59.13
mg/l
0.07
25
172
11
68
1.67
0.74
3.5
3.7
1.02
2.51
mmol/l
0.70
11
59
9
56
1.65
0.74
1.6
1.2
—
—
—
0
0
5
25
2.04
0.73
1.0
1.2
—
—
—
0
0
18
127
1.48
0.72
1.3
1.7
—
—
—
0
0
44
363
1.31
0.72
1.8
1.7
—
—
—
0
0
13
85
1.58
0.72
5.6
2.8
—
—
—
0
0
5
26
1.96
0.71
1.0
1.2
—
—
—
0
0
10
61
1.69
0.70
1.1
1.2
0.91
0.89
g/l
—
10
61
10
61
1.69
0.70
1.0
1.1
—
—
—
0
0
10
62
1.66
0.67
2.1
1.5
0.03
0.13
e6/l
—
10
57
26
201
1.36
0.65
3.1
2.1
—
—
—
0
0
34
275
1.31
0.64
3.6
3.0
—
—
—
0
0
26
202
1.35
0.63
1.4
1.7
951.34
1010.94
mu/l
0.17
21
166
16
114
1.46
0.62
2.7
2.2
331.56
379.50
nmol/l
0.58
16
107
8
53
1.54
0.59
1.6
1.7
—
3.11
—
0
12
8
54
1.51
0.58
3.3
8.8
0.99
0.60
%
—
8
54
8
54
1.51
0.58
1.5
1.2
—
—
—
0
0
6
37
1.65
0.56
1.3
1.4
—
—
—
0
0
9
63
1.46
0.53
1.6
1.2
—
—
—
0
0
28
227
1.29
0.52
1.7
1.5
—
—
—
0
0
12
166
0.70
0.51
1.3
1.2
—
—
—
0
0
33
277
1.25
0.47
4.7
3.9
9.89
11.49
mg/mmol
0.07
23
168
24
194
1.29
0.46
1.7
1.4
304.00
600.00
titre
—
5
48
8
55
1.48
0.44
3.3
8.8
1.33
1.18
%
—
8
55
8
55
1.48
0.44
3.3
8.8
91.50
94.81
%
—
8
55
5
32
1.58
0.42
4.0
1.8
—
—
—
0
0
12
88
1.40
0.41
3.8
7.4
7.43
7.40
ph
—
7
42
48
427
1.19
0.39
1.8
1.7
—
—
—
0
0
13
98
1.36
0.39
1.1
1.4
—
—
—
0
0
39
341
1.20
0.38
9.6
6.5
—
—
—
0
0
9
71
1.29
0.37
5.3
7.9
—
—
—
0
0
9
71
1.29
0.37
1.3
1.2
—
—
—
0
0
6
43
1.41
0.35
1.2
1.9
—
—
—
0
0
7
96
0.71
0.32
1.7
1.6
—
—
—
0
0
110
1059
1.20
0.31
18.3
13.9
13.28
13.40
%
0.70
110
1044
7
55
1.29
0.30
6.0
7.3
23.24
24.88
mmol/l
—
7
55
5
37
1.36
0.24
2.0
2.4
—
—
—
0
0
7
94
0.73
0.23
1.7
1.6
—
—
—
0
0
5
41
1.23
0.22
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
8.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
1730.40
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
3173.60
—
0
5
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
31
280
1.14
0.21
4.7
3.4
7.39
7.40
ph
0.77
21
193
12
99
1.23
0.20
4.3
1.9
10.73
10.61
g/l
0.04
12
94
8
71
1.13
0.16
1.6
1.2
—
—
—
0
0
8
71
1.13
0.16
1.6
1.2
—
—
—
0
0
15
130
1.17
0.16
1.5
1.3
—
—
—
0
0
8
72
1.12
0.16
1.6
1.2
—
—
—
0
0
9
79
1.15
0.15
1.6
1.4
—
—
—
0
0
30
321
0.92
0.12
6.8
6.7
—
—
—
0
0
21
226
0.92
0.09
1.6
1.3
1.57
7.90
u/ml
—
8
91
8
78
1.03
0.07
2.1
1.7
—
—
—
0
0
18
168
1.08
0.06
1.8
1.6
—
—
—
0
0
17
171
0.99
0.00
2.2
3.1
37.11
787.15
ng/l
—
9
91
26
261
1.00
0.00
1.6
1.3
12.28
28.15
iu/ml
—
9
71
0
8
0.00
0.00
0.0
1.4
—
273.88
—
0
8
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
4.3
—
10.98
—
0
8
0
5
0.00
-0.00
0.0
2.6
—
2.10
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
6.26
—
0
6
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
85.67
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
10.67
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
90.88
—
0
5
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
50.62
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
0.47
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_ENDOMETRIOSIS_SKIN_SCAR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_ENDOMETRIOSIS_SKIN_SCAR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_ENDOMETRIOSIS_SKIN_SCAR – Endometriosis in cutaneous scar

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data