No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
176 |
4. Check minimum number of eventsNone |
176 |
5. Include endpointsNone |
176 |
6. Filter based on genotype QC (FinnGen only) |
150 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Juvenile cataract
based on the number of shared cases.
Similar with more cases:
- Other cataract
- Disorders of lens
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 150 | 91 | 59 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 42.57 | 40.16 | 46.28 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 158
- Matched controls
- 1580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H26.01
ICD-10 Finland
Infantile, juvenile and presenile cataract
+∞
226.3
158
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
41.6
120.7
128
147
H26.02
ICD-10 Finland
Presenil cataract
64.4
95.3
55
13
Z96.1
ICD-10 Finland
Presence of intraocular lens
26.6
94.3
81
60
H26.4
ICD-10 Finland
After-cataract
29.2
90.6
71
43
CJB10
NOMESCO Finland
Laser discission of secondary cataract
25.3
66.6
52
30
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
7.0
34.2
92
261
H26.2
ICD-10 Finland
Complicated cataract
35.8
21.4
27
9
H25.1
ICD-10 Finland
Senile nuclear cataract
5.8
20.3
46
105
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.3
15.6
53
166
WX100
NOMESCO Finland
Conjunctival surface anesthesia
5.9
14.5
29
58
ZXA05
NOMESCO Finland
Left side
4.0
14.4
56
192
ZXA00
NOMESCO Finland
Right side
3.9
14.4
58
204
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.6
10.9
29
74
A10AB05
ATC
insulin aspart; parenteral
4.7
9.9
25
61
H33.0
ICD-10 Finland
Retinal detachment with retinal break
11.1
9.3
17
17
Q12.0
ICD-10 Finland
Congenital cataract
39.1
9.1
11
*
S01ED51
ATC
timolol, combinations; ophthalmic
5.3
8.8
19
40
A10AE04
ATC
insulin glargine; parenteral
4.1
8.5
26
73
S01EE01
ATC
latanoprost; ophthalmic
7.5
7.5
17
25
H26.1
ICD-10 Finland
Traumatic cataract
83.9
7.5
8
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
+∞
7.3
7
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
16.8
7.3
11
7
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.9
7.3
23
66
S01BC05
ATC
ketorolac; ophthalmic
10.8
7.2
13
13
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.5
7.0
70
386
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.6
6.9
17
40
A10AE05
ATC
insulin detemir; parenteral
4.6
6.9
17
40
TPH07
NOMESCO Finland
Cathetrisation of artery
3.7
6.7
23
70
WX140
NOMESCO Finland
Parabulbar anesthesy
8.0
6.6
14
19
H52.1
ICD-10 Finland
Myopia
5.7
6.6
18
35
H40.0
ICD-10 Finland
Glaucoma suspect
4.4
6.5
17
42
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.8
6.4
17
32
A10AB01
ATC
insulin (human); parenteral
5.8
6.4
17
32
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
6.2
65
362
T89
ICPC
Diabetes insulin dependent
4.3
6.1
16
40
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
29
120
2.74
5.08
7.1
14.7
13.06
13.08
kpa
0.01
29
114
29
120
2.74
5.08
7.1
14.7
5.20
5.16
kpa
0.11
29
113
29
121
2.71
5.00
6.3
14.7
0.07
1.10
mmol/l
0.95
24
98
24
97
2.74
4.38
35.9
14.6
24.15
24.97
mmol/l
0.49
24
97
75
501
1.95
4.06
3.3
3.2
30.07
28.21
u/l
0.28
69
478
101
760
1.91
3.68
10.0
5.9
7.12
6.48
mmol/l
1.21
96
710
83
600
1.81
3.31
3.8
2.8
71.37
72.69
nmol/l
0.15
78
559
10
25
4.20
3.14
1.9
1.4
16.23
33.79
u/l
—
10
20
17
70
2.60
2.99
7.0
21.3
94.94
94.08
%
0.31
17
70
17
70
2.60
2.99
6.9
21.1
0.59
0.69
%
0.41
17
70
58
391
1.76
2.83
1.8
1.4
0.76
1.25
u/ml
0.60
17
116
17
73
2.49
2.76
7.0
20.4
1.21
1.56
%
0.71
17
73
51
337
1.76
2.64
1.6
1.6
23.88
20.38
nmol/l
0.57
45
294
74
544
1.68
2.60
2.0
1.9
89.17
95.42
pmol/l
0.66
44
291
39
239
1.84
2.58
3.2
3.3
144.59
226.35
ng/l
0.32
27
155
13
51
2.69
2.51
1.3
1.3
—
—
—
0
0
12
46
2.74
2.42
6.5
5.2
1.98
1.56
%
0.73
12
41
48
321
1.71
2.36
2.2
2.4
3.33
2.62
mg/l
1.40
42
285
90
711
1.62
2.28
6.4
7.2
10.65
11.05
umol/l
0.20
84
680
20
102
2.10
2.22
1.5
1.2
368.43
435.08
u/ml
0.07
20
94
8
24
3.45
2.21
2.6
1.6
—
—
—
0
0
77
594
1.58
2.10
2.7
1.9
1.37
1.47
mmol/l
0.57
68
520
140
1256
2.01
2.08
7.2
5.5
40.53
38.37
mmol/mol
1.22
130
1205
10
39
2.67
1.98
1.1
1.4
—
—
—
0
0
8
27
3.06
1.96
1.8
1.9
—
—
—
0
0
8
27
3.06
1.96
1.3
1.2
—
—
—
0
0
26
155
1.81
1.87
4.0
2.4
409.12
367.10
nmol/l
0.46
26
147
147
1353
2.24
1.86
5.6
4.7
1.43
1.45
mmol/l
0.12
137
1278
147
1354
2.23
1.84
5.7
4.7
4.57
4.72
mmol/l
1.06
140
1287
9
35
2.66
1.83
2.0
1.5
—
—
—
0
0
7
23
3.14
1.82
5.9
2.7
15.59
16.27
%
—
7
23
9
36
2.59
1.77
2.1
2.1
—
—
—
0
0
8
31
2.66
1.68
11.3
5.8
—
1222.00
—
0
5
16
84
2.01
1.66
21.0
4.6
1.72
1.09
mmol/l
0.45
11
62
5
14
3.65
1.63
1.0
1.1
—
—
—
0
0
22
132
1.77
1.56
22.1
5.7
2.81
1.66
mmol/l
1.07
17
115
6
21
2.93
1.52
1.3
1.2
—
—
—
0
0
9
37
2.52
1.50
3.8
2.1
122.44
128.83
g/l
—
9
29
147
1371
2.04
1.48
6.2
5.2
2.68
2.81
mmol/l
1.09
138
1299
9
38
2.45
1.48
1.2
1.1
—
1.06
—
0
7
18
104
1.82
1.44
3.3
2.8
58.67
72.53
ml/min/173m2
—
6
43
54
415
1.46
1.39
5.2
2.8
51.18
56.19
u/l
0.82
49
389
26
170
1.63
1.37
17.2
10.9
104.12
104.59
mmol/l
0.20
26
170
9
43
2.16
1.32
1.9
1.4
—
—
—
0
0
15
84
1.87
1.32
2.6
1.7
—
—
—
0
0
43
319
1.48
1.31
2.6
2.3
—
—
—
0
0
75
619
1.40
1.28
3.4
2.8
—
—
estimate
—
0
0
8
36
2.29
1.26
1.8
1.2
—
—
—
0
0
20
126
1.67
1.21
1.3
1.3
98.34
139.81
u/ml
—
8
49
49
379
1.42
1.20
7.7
4.0
8.34
11.74
mg/mmol
0.33
38
233
23
151
1.61
1.20
1.7
2.3
—
—
—
0
0
15
87
1.80
1.20
1.0
1.1
—
—
—
0
0
0
35
0.00
1.16
0.0
1.5
—
56.77
—
0
35
8
41
2.00
1.10
1.9
1.3
—
—
—
0
0
11
59
1.93
1.10
36.1
8.0
1.46
1.33
mg/l
0.25
11
54
138
1286
1.58
1.09
4.5
4.0
1.25
1.31
mmol/l
0.52
127
1211
29
208
1.48
1.04
5.9
2.8
1.42
3.23
e6/l
0.89
15
100
7
34
2.11
1.04
13.6
1.2
1.24
0.89
nmol/l
—
7
29
139
1301
1.57
1.03
18.1
12.7
89.89
89.31
ml/min/173m2
0.11
129
1173
10
54
1.91
0.99
31.6
4.3
9.22
9.22
kpa
—
10
54
5
23
2.21
0.98
1.0
1.1
—
—
—
0
0
0
32
0.00
0.96
0.0
1.2
—
8.12
—
0
27
6
27
2.27
0.94
17.3
4.0
9.42
10.56
pmol/l
—
6
27
54
441
1.34
0.94
9.3
3.3
—
—
—
0
0
6
28
2.19
0.92
1.3
1.1
—
—
—
0
0
6
29
2.11
0.90
3.2
1.4
—
—
—
0
0
45
360
1.35
0.89
9.3
3.0
0.22
0.48
e6/l
1.15
34
260
6
30
2.04
0.88
1.7
1.2
—
—
—
0
0
23
164
1.47
0.86
2.1
1.5
—
—
—
0
0
14
211
0.63
0.86
3.9
2.5
2.24
0.67
ug/l
—
9
112
6
32
1.91
0.82
1.8
1.5
—
—
—
0
0
24
321
0.70
0.82
1.5
1.3
18.82
24.52
iu/ml
—
6
92
8
48
1.70
0.80
5.0
3.1
23.81
23.97
mmol/l
—
8
48
6
33
1.85
0.80
1.2
1.2
—
1.17
—
0
12
13
83
1.62
0.77
1.6
2.4
17.11
6.77
ug/l
0.30
13
74
5
26
1.95
0.71
2.4
1.3
—
—
—
0
0
92
831
1.26
0.69
14.2
11.1
3.99
3.97
e9/l
0.04
80
728
5
27
1.88
0.69
1.0
1.2
—
—
—
0
0
5
27
1.88
0.69
1.0
1.2
—
—
—
0
0
5
27
1.88
0.69
1.6
1.2
—
—
—
0
0
13
86
1.56
0.68
35.8
6.2
24.28
24.55
mmol/l
0.09
13
86
5
29
1.75
0.64
1.4
1.3
—
—
—
0
0
21
157
1.39
0.63
2.2
1.5
—
—
—
0
0
29
230
1.32
0.61
5.2
2.6
0.36
0.93
e6/l
1.92
15
122
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
17
124
1.42
0.58
1.8
2.1
—
—
—
0
0
15
107
1.44
0.58
4.3
3.4
—
—
—
0
0
32
388
0.78
0.57
2.0
1.7
—
—
—
0
0
16
116
1.42
0.57
29.4
5.3
5.38
4.67
kpa
0.45
16
116
68
756
0.82
0.55
7.8
3.4
63.79
0.00
estimate
0.48
19
149
27
216
1.30
0.54
2.4
1.6
—
—
—
0
0
6
39
1.56
0.53
1.2
1.7
1125.33
470.95
mg/l
—
6
39
11
77
1.46
0.47
1.9
2.5
183.82
42.53
u/ml
0.57
11
72
109
1028
1.19
0.43
11.3
8.6
80.70
77.82
u/l
0.41
103
976
77
706
1.18
0.43
4.1
3.1
135.11
101.31
ug/l
0.80
70
673
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
8.01
—
0
15
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
8
60
1.35
0.41
1.9
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
14
106
1.35
0.40
1.2
1.3
—
—
—
0
0
8
61
1.33
0.40
2.9
1.5
—
—
—
0
0
30
254
1.22
0.39
2.2
2.1
—
—
—
0
0
69
750
0.86
0.39
7.6
3.4
0.00
0.00
estimate
-0.00
18
147
5
36
1.40
0.38
1.8
1.0
—
15.11
—
0
19
10
72
1.42
0.38
28.2
4.1
0.65
0.63
%
—
10
72
6
42
1.45
0.36
1.8
1.9
—
—
—
0
0
10
73
1.39
0.35
1.0
1.1
1.41
1.54
g/l
—
10
73
133
1286
1.22
0.35
6.7
5.2
1.88
1.81
mu/l
0.38
124
1207
31
268
1.19
0.33
1.7
1.6
—
—
—
0
0
7
52
1.36
0.31
1.3
1.2
—
47.17
—
0
6
7
52
1.36
0.31
1.4
1.3
—
—
—
0
0
71
761
0.88
0.31
7.3
3.5
0.00
0.00
estimate
-0.00
17
138
10
75
1.36
0.31
1.0
1.1
0.84
0.88
g/l
—
10
75
7
55
1.29
0.30
4.7
1.6
0.26
0.22
g/l
—
7
55
8
62
1.31
0.28
2.0
1.7
—
—
—
0
0
8
66
1.22
0.27
1.9
1.4
—
—
—
0
0
26
296
0.85
0.26
1.4
1.3
1.82
6.19
u/ml
1.04
11
121
5
42
1.20
0.21
1.4
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
210.75
—
0
11
0
10
0.00
0.21
0.0
11.7
—
36.20
—
0
5
0
10
0.00
0.21
0.0
1.0
—
2039.80
—
0
10
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
5.5
—
96.05
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
15
128
1.19
0.19
5.8
5.6
—
—
—
0
0
19
166
1.16
0.19
1.9
1.6
1133.50
1179.81
nmol/l
0.06
14
129
112
1087
1.10
0.19
5.8
4.4
14.50
14.54
pmol/l
0.07
103
1016
134
1313
1.14
0.18
5.0
4.3
6.17
5.79
mmol/l
1.23
125
1231
11
91
1.22
0.18
12.6
4.2
1.22
1.22
mmol/l
0.03
11
84
7
61
1.15
0.18
1.6
1.6
—
—
—
0
0
26
285
0.90
0.16
4.3
3.7
25.26
22.37
%
—
8
108
30
276
1.11
0.15
2.5
2.2
—
—
—
0
0
35
328
1.09
0.12
1.6
2.2
1.19
0.94
mg/l
0.29
26
257
54
563
0.94
0.11
7.3
3.2
0.00
0.01
estimate
0.50
13
120
6
55
1.09
0.09
1.7
4.3
197.50
186.25
%
—
6
55
6
57
1.05
0.08
1.8
4.7
93.50
99.54
%
—
6
57
38
396
0.95
0.07
8.6
3.5
0.00
0.01
estimate
0.50
16
135
34
327
1.05
0.05
6.5
3.4
1.02
1.02
kg/l
0.08
28
205
41
421
0.96
0.03
6.2
2.9
0.00
0.00
estimate
-0.00
12
111
139
1384
1.04
0.00
24.3
14.0
25.22
21.06
mg/l
0.63
117
1109
108
1083
0.99
0.00
3.6
3.6
—
—
—
0
0
46
455
1.02
0.00
4.2
3.0
16.32
25.03
ng/l
1.01
24
271
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
70.80
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
83
0.96
-0.00
1.0
1.3
—
—
—
0
0
5
57
0.87
-0.00
2.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
15.25
—
0
8
0
7
0.00
-0.00
0.0
2.6
—
4.73
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
0.25
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
6
66
0.91
-0.00
3.5
2.4
42.83
41.90
u/l
—
6
60
0
5
0.00
-0.00
0.0
1.4
—
55.40
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
18.40
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
-0.00
5.2
4.0
52.70
52.25
%
—
6
64
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
202.67
—
0
6
0
7
0.00
-0.00
0.0
2.6
—
10.64
—
0
7
5
58
0.86
-0.00
1.2
1.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: H7_JUVENILE_CATARACT – Juvenile cataract
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).