Respiratory tuberculosis, not confirmed

AB1_RESP_TUBERCU_NONCONF

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A16
  • Hospital discharge: ICD-9 01[1-2]
  • Hospital discharge: ICD-8 01[1-2]
  • Hospital discharge: excluded ICD-9 01[1-2].A
  • Cause of death: ICD-10 A16
  • Cause of death: ICD-9 01[1-2]
  • Cause of death: ICD-8 01[1-2]
  • Cause of death: excluded ICD-9 01[1-2].A

2 out of 7 registries used, show all original rules.

1844

4. Check minimum number of events

None

1844

5. Include endpoints

None

1844

6. Filter based on genotype QC (FinnGen only)

1651

Control definitions (FinnGen only)

Control exclude
AB1_TUBERCULOSIS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26949 10715 15412
Only index persons 12955 6283 6672
Unadjusted period prevalence (%)
Whole population 0.39 0.31 0.43
Only index persons 0.24 0.23 0.25
Median age at first event (years)
Whole population 49.87 48.85 50.29
Only index persons 38.41 38.00 38.81

-FinnGen-

Key figures

All Female Male
Number of individuals 1651 582 1069
Unadjusted period prevalence (%) 0.39 0.21 0.49
Median age at first event (years) 40.78 33.02 45.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1704
Matched controls
17040
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
+∞
307.7
396
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
280.1
261
*
01220
ICD-8 Finland
Other respiratory tuberculosis, Pleurisy with effusion without mention of cause
+∞
217.5
204
*
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
2062.8
184.8
176
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
44.7
183.1
109
26
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
154.6
146
*
01210
ICD-8 Finland
Other respiratory tuberculosis, Tuberculosis pleurae, pleuritis exsudativa tuberculosa
+∞
132.0
125
*
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
49.7
91.2
53
11
0110K, ,
ICD-8 Finland
+∞
75.6
72
*
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
+∞
71.4
68
*
0110X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, EPÄILTY]
+∞
65.0
62
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.0
64.7
344
1327
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.3
64.6
282
970
A16.5
ICD-10 Finland
Tuberculous pleurisy, without mention of bacteriological or histological confirmation
+∞
59.7
57
*
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
12.6
56.7
56
46
A16.1
ICD-10 Finland
Tuberculosis of lung, bacteriological and histological examination not done
+∞
49.2
47
*
0110J, ,
ICD-8 Finland
+∞
45.0
43
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.4
44.5
384
1854
A16.9
ICD-10 Finland
Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
+∞
41.8
40
*
0120X
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, EPÄILTY]
+∞
38.7
37
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
37.6
36
*
0110A, ,
ICD-8 Finland
+∞
35.5
34
*
R03BB04
ATC
tiotropium bromide; inhalant
2.3
32.7
300
1470
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
32.4
31
*
01104
ICD-8 Finland
Pulmonary tuberculosis, Tuberculoma pulmonum
+∞
30.3
29
*
01106
ICD-8 Finland
Pulmonary tuberculosis, Pulmonum alia sive NUD
+∞
30.3
29
*
0119X
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, EPÄILTY]
+∞
29.2
28
*
01109
ICD-8 Finland
Pulmonary tuberculosis, Unspecified
+∞
27.2
26
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.5
25.4
173
739
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
25.4
396
2339
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
7.7
25.1
35
46
01297
ICD-8 Finland
Other respiratory tuberculosis, Suspecta
+∞
25.1
24
*
R03DA04
ATC
theophylline; systemic, rectal
2.2
21.1
188
902
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
20.9
644
4579
R03BB01
ATC
ipratropium bromide; inhalant
2.3
19.8
152
685
H02AB06
ATC
prednisolone; systemic
1.6
18.3
799
6121
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.6
18.3
60
170
01710
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum colli
+∞
17.7
17
*
1240
FHL
Bronchoscopy
3.8
17.7
55
150
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.5
17.6
110
450
51120
ICD-8 Finland
Pleurisy, Other specified forms of effusion, except tuberculous
50.5
17.0
20
*
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.0
16.8
190
996
TGC00
NOMESCO Finland
Bronchial lavation
3.3
16.7
64
201
0120B
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, HISTOLOGISESTI VARMENNETTU]
+∞
15.6
15
*
R03AC12
ATC
salmeterol; inhalant
2.3
15.5
123
561
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
15.3
278
1696
J45.8
ICD-10 Finland
Mixed asthma
3.0
15.3
67
228
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.1
15.2
155
781
R03AC02
ATC
salbutamol; inhalant
1.5
14.7
785
6181
48609
ICD-8 Finland
Pneumonia, unspecified
4.7
14.7
34
74
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.4
14.3
102
444
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
13.8
100
439
A15.6
ICD-10 Finland
Tuberculous pleurisy, confirmed bacteriologically and histologically
+∞
13.6
13
*
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
+∞
13.6
13
*
01908
ICD-8 Finland
Late effects of tuberculosis, Sequelae aliae o tuberculosis organorum respirationis
+∞
13.6
13
*
0118X
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, EPÄILTY]
+∞
13.6
13
*
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
34.3
13.5
17
5
J96.1
ICD-10 Finland
Chronic respiratory failure
2.7
13.5
72
273
48509
ICD-8 Finland
Bronchopneumonia, unspecified
5.3
13.4
27
52
M05BA04
ATC
alendronic acid; oral
1.9
13.1
175
969
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
2.7
12.9
72
279
J47
ICD-10 Finland
Bronchiectasis
3.2
12.8
50
159
48601
ICD-8 Finland
More specifically, unspecified pneumonia and the pleural irritation caused by it
11.1
12.5
23
21
01292
ICD-8 Finland
Other respiratory tuberculosis, Lymphonodorum tracheobronchialium et mediastini
+∞
12.5
12
*
A70
ICPC
Tuberculosis
130.9
12.4
13
*
13597
ICD-8 Finland
Sarcoidosis, Suspecta
6.1
12.1
21
35
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
8.7
12.0
25
29
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
4.2
11.8
31
75
0112X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, EPÄILTY]
+∞
11.5
11
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
11.5
11
*
51899
ICD-8 Finland
Bronchiectasis
12.8
11.1
19
15
J01MA14
ATC
moxifloxacin; systemic
1.8
11.0
163
933
L04AA13
ATC
[U] leflunomide
3.3
11.0
40
122
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
8.6
10.5
22
26
132
Kela drug reimbursment
Sarcoidosis
4.7
10.5
24
52
03199
ICD-8 Finland
Other diseases due to Mycobacteria, Other and unspecified
+∞
10.4
10
*
01103
ICD-8 Finland
Pulmonary tuberculosis, Bronchialis
+∞
10.4
10
*
R03BB02
ATC
oxitropium bromide; inhalant
3.6
10.3
34
97
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
4.3
10.3
26
61
J43.9
ICD-10 Finland
Emphysema, unspecified
2.8
10.1
49
177
R05CB01
ATC
acetylcysteine; inhalant, oral
2.8
10.1
48
172
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
9.9
227
1468
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
9.7
286
1962
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
55.3
9.7
11
*
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
3.1
9.5
38
123
13599
ICD-8 Finland
Sarcoidosis, Unspecified
7.2
9.5
22
31
A16.8
ICD-10 Finland
Other respiratory tuberculosis, without mention of bacteriological or histological confirmation
+∞
9.4
9
*
0110B, ,
ICD-8 Finland
+∞
9.4
9
*
Y0499
ICD-8 Finland
Investigation of respiratory system
3.3
9.3
35
109
L04AX01
ATC
azathioprine; systemic
2.5
9.3
59
245
R03BA01
ATC
beclometasone; inhalant
1.6
9.1
216
1405
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
8.9
162
986
A98
ICPC
Health maint/preventive medicine
0.7
8.6
1095
12134
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
4.4
8.6
21
48
J94.9
ICD-10 Finland
Pleural condition, unspecified
4.6
8.6
20
44
51109
ICD-8 Finland
Pleurisy, Sicca NUD
20.1
8.5
12
6
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.0
8.4
90
464
01202, ,
ICD-8 Finland
+∞
8.3
8
*
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.5
8.3
49
197
N05CD07
ATC
temazepam; oral
1.5
8.2
262
1822
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.0
8.2
35
118
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
8.2
110
611
P01BA02
ATC
hydroxychloroquine; oral
1.8
7.9
108
603
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.6
7.9
43
166
49300
ICD-8 Finland
Asthma, bronchiale
2.5
7.7
48
198
R95
ICPC
Chron obstructive pulmonary disease
2.2
7.6
65
307
A07EC01
ATC
sulfasalazine; oral, rectal
1.8
7.6
106
596
5111B
ICD-9 Finland
Pleurisy, With effusion, with mention of a bacterial cause other than tuberculosis[PLEURITIS EXSUDATIVA ALIA DEFINITA]
25.1
7.6
10
*
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
3.5
7.6
25
72
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
2.9
7.4
33
114
J46
ICD-10 Finland
Status asthmaticus
2.5
7.4
45
183
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
80.4
7.4
8
*
A02BC01
ATC
omeprazole; systemic
1.4
7.4
439
3426
H02AB07
ATC
prednisone; oral
1.5
7.3
233
1619
A16.4
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation
+∞
7.3
7
*
R03BA02
ATC
budesonide; inhalant
1.5
7.1
246
1740
J01FA06
ATC
roxithromycin; oral
1.3
7.0
571
4667
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
3.7
6.9
21
57
A02BA02
ATC
ranitidine; systemic
1.4
6.9
342
2584
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
6.9
83
446
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
40.2
6.8
8
*
Z22.30
ICD-10 Finland
Latent tuberculosis
22.6
6.7
9
*
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
12.3
6.6
11
9
R04.2
ICD-10 Finland
Haemoptysis
1.9
6.5
72
377
49109
ICD-8 Finland
Chronic bronchitis, Unspecified
5.3
6.5
18
34
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
14.4
6.4
10
7
A10BA02
ATC
metformin; oral
0.7
6.4
297
3889
L01BA01
ATC
methotrexate; systemic
2.1
6.3
54
256
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
3.9
6.3
18
47
R03AC13
ATC
formoterol; inhalant
1.8
6.3
87
490
A16.3
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation
+∞
6.3
6
*
01230
ICD-8 Finland
Other respiratory tuberculosis, Tuberculous laryngitis
+∞
6.3
6
*
01904
ICD-8 Finland
Late effects of tuberculosis, Adhaesiones pleurae
+∞
6.3
6
*
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
6.3
6
*
01105
ICD-8 Finland
Pulmonary tuberculosis, Disseminata pulmonum
+∞
6.3
6
*
0116X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA, EPÄILTY]
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
57
210
2.77
11.31
5.6
2.6
—
—
—
0
0
55
208
2.70
10.41
3.6
2.5
—
—
—
0
0
1007
11323
0.73
8.90
6.2
6.2
2.53
2.51
mmol/l
0.38
917
10235
1125
12399
0.73
8.42
37.6
29.9
7.26
7.00
e9/l
2.06
1083
12005
1125
12397
0.73
8.39
37.7
30.1
130.76
131.62
g/l
1.05
1100
12173
1125
12395
0.73
8.36
37.4
29.8
30.37
30.44
pg
0.68
1099
12169
1125
12395
0.73
8.36
37.5
29.9
4.34
4.36
e12/l
0.48
1081
12004
1125
12395
0.73
8.36
38.5
30.5
39.35
39.29
%
0.13
1099
12161
1125
12394
0.73
8.35
37.6
29.9
247.73
239.07
e9/l
3.75
1086
12053
1125
12393
0.73
8.33
37.5
29.8
91.89
91.86
fl
0.08
1099
12168
985
11036
0.75
7.88
5.4
5.4
4.44
4.39
mmol/l
0.83
896
10030
1122
12329
0.74
7.83
32.9
26.8
85.55
86.22
umol/l
0.20
1095
12107
1055
11690
0.74
7.71
21.9
18.3
—
—
—
0
0
1107
12173
0.74
7.61
30.5
24.7
4.02
4.02
mmol/l
0.04
1079
11870
1107
12163
0.74
7.48
30.2
24.5
139.50
139.59
mmol/l
0.54
1080
11875
980
10929
0.76
7.16
5.3
5.3
1.44
1.43
mmol/l
0.35
884
9834
1013
11237
0.76
7.05
5.6
5.7
6.08
6.11
mmol/l
0.25
913
10007
940
10501
0.77
6.67
4.5
4.5
1.29
1.27
mmol/l
0.42
842
9351
993
10995
0.77
6.46
7.1
7.3
40.23
40.53
mmol/mol
0.51
905
10040
1105
12048
0.76
6.27
15.6
12.9
24.92
24.94
u/l
0.00
1063
11575
248
3206
0.73
4.75
2.9
3.5
0.93
0.85
ug/l
0.34
171
2252
980
10702
0.80
4.72
5.5
5.3
1.95
2.05
mu/l
2.00
889
9611
38
178
2.16
4.68
1.7
1.5
—
—
—
0
0
38
178
2.16
4.68
1.7
1.5
—
—
—
0
0
38
178
2.16
4.68
1.7
1.5
—
—
—
0
0
38
178
2.16
4.68
1.7
1.5
—
—
—
0
0
15
35
4.31
4.63
1.1
1.3
—
—
—
0
0
1080
11636
0.80
4.40
27.1
20.1
28.71
28.34
mg/l
0.13
964
9987
467
5498
0.79
4.34
5.2
6.0
2.87
4.54
ug/l
1.30
408
4863
14
33
4.27
4.32
1.1
1.4
—
—
—
0
0
36
172
2.12
4.24
2.1
1.7
0.75
0.88
g/l
0.24
24
137
170
1236
1.42
4.24
1.8
1.6
—
—
—
0
0
245
1921
1.32
3.81
7.6
7.1
1.46
0.99
mmol/l
1.06
207
1554
245
1931
1.31
3.67
7.4
7.1
5.16
5.08
kpa
0.55
235
1844
245
1931
1.31
3.67
7.4
7.1
11.48
11.65
kpa
0.20
235
1846
243
1924
1.31
3.52
7.6
7.2
7.42
7.41
ph
0.36
143
1089
61
371
1.67
3.49
2.1
2.3
121.94
126.66
g/l
0.83
47
297
851
9243
0.84
3.13
31.4
24.9
14.10
13.96
%
2.10
843
9084
126
935
1.38
2.85
3.6
2.9
10.35
10.92
g/l
0.58
118
853
293
3487
0.81
2.82
3.3
3.6
—
—
—
0
0
137
1033
1.35
2.81
7.5
6.6
25.18
24.31
mmol/l
1.48
131
990
184
1451
1.30
2.77
1.4
1.3
552.56
455.16
titre
0.31
43
335
30
161
1.88
2.67
1.3
1.2
26.00
15.01
u/l
0.98
25
147
846
9123
0.86
2.63
34.6
26.6
330.34
330.92
g/l
1.01
836
9039
807
8729
0.86
2.60
6.6
5.4
6446.29
1670.75
e6/l
0.37
17
167
214
1736
1.27
2.59
8.2
7.4
94.61
95.09
%
0.48
205
1678
430
4886
0.84
2.53
4.2
4.1
—
0.75
—
0
20
21
102
2.07
2.47
2.9
1.3
7.84
6.95
g/l
0.51
16
76
21
102
2.07
2.47
2.9
1.3
0.50
0.45
g/l
0.22
16
75
21
102
2.07
2.47
2.9
1.3
2.54
2.77
g/l
0.28
15
76
21
103
2.05
2.42
2.7
1.3
—
—
—
0
0
17
77
2.22
2.37
1.3
1.4
2.23
0.67
u/ml
0.44
12
44
66
453
1.48
2.34
2.0
1.8
6.10
7.48
iu/ml
0.23
15
107
11
39
2.83
2.34
3.3
2.2
—
—
—
0
0
249
2081
1.23
2.33
2.5
2.1
—
—
—
0
0
404
4583
0.84
2.30
2.0
1.9
1.31
1.31
mmol/l
0.04
342
3739
33
193
1.72
2.27
1.3
1.1
—
—
—
0
0
421
4751
0.85
2.25
3.7
4.1
13.48
9.33
mg/mmol
0.57
260
3026
409
4626
0.85
2.24
3.1
3.5
61.43
48.43
mg/l
0.49
268
3035
196
1605
1.25
2.21
2.2
1.8
—
—
—
0
0
261
3065
0.82
2.18
1.3
1.3
—
—
—
0
0
8
24
3.34
2.18
5.4
4.6
—
—
—
0
0
826
8844
0.87
2.12
4.3
4.1
15.16
15.09
pmol/l
0.30
743
7882
98
742
1.34
2.02
2.1
1.8
2.13
1.89
ug/l
0.07
83
643
13
57
2.29
1.98
1.0
1.0
7.61
2.56
u/ml
—
6
24
83
615
1.37
1.97
1.5
1.3
279.96
223.79
u/ml
0.25
75
562
33
203
1.64
1.93
1.2
1.3
—
—
—
0
0
543
5953
0.87
1.92
3.3
2.9
—
—
estimate
—
0
0
183
1513
1.23
1.92
2.1
1.4
—
—
—
0
0
88
663
1.35
1.89
1.6
1.4
—
—
—
0
0
52
361
1.45
1.80
2.7
3.0
88.86
88.39
%
0.20
52
352
22
123
1.80
1.80
1.1
1.4
—
—
—
0
0
593
6437
0.88
1.78
2.4
2.3
90.30
93.24
pmol/l
0.80
324
3451
46
316
1.47
1.70
2.0
2.3
11.59
12.74
mg/l
0.37
46
291
423
4683
0.87
1.69
3.3
3.4
6.92
7.16
mmol/l
0.57
353
3890
661
7103
0.89
1.65
19.1
20.0
1.31
1.38
inr
2.33
578
6010
39
570
0.68
1.64
1.3
1.2
83.91
140.40
u/ml
1.00
12
197
9
188
0.48
1.62
1.6
1.7
—
—
—
0
0
18
98
1.85
1.62
2.8
2.9
25.36
28.09
mg/l
0.07
11
74
95
744
1.29
1.60
2.4
1.8
1.47
1.59
g/l
0.09
87
671
38
255
1.50
1.58
2.8
4.0
0.66
1.80
%
2.64
31
225
57
414
1.39
1.58
2.7
3.1
7.74
7.74
kpa
0.01
57
406
826
8746
0.89
1.58
6.0
5.0
—
2.44
—
0
15
73
552
1.34
1.58
3.1
3.2
24.95
25.03
mmol/l
0.05
73
544
757
8055
0.89
1.58
6.7
5.3
6.93
6.89
mmol/l
0.19
729
7710
18
99
1.83
1.57
4.0
2.5
15.25
15.98
%
0.54
18
99
28
176
1.60
1.55
1.1
1.4
162.00
167.44
au/ml
—
8
49
280
2461
1.16
1.53
6.2
4.8
—
—
—
0
0
5
15
3.34
1.52
4.2
2.6
0.82
0.68
ug/l
—
5
15
78
1003
0.77
1.51
2.2
2.3
10.80
12.25
nmol/l
0.79
65
883
14
73
1.93
1.44
1.6
1.8
69.21
72.42
%
0.37
14
67
5
16
3.13
1.44
13.0
13.4
4.96
5.19
mmol/l
—
5
16
26
165
1.58
1.40
3.0
3.9
60.33
58.16
%
0.19
21
146
136
1133
1.22
1.38
5.6
4.1
0.77
0.74
%
0.04
54
382
15
82
1.84
1.35
11.6
1.7
—
—
—
0
0
16
90
1.79
1.33
7.1
1.3
—
—
—
0
0
143
1207
1.20
1.28
5.6
4.2
0.92
0.93
%
0.02
60
414
15
84
1.79
1.27
1.1
1.1
—
—
—
0
0
16
92
1.75
1.25
1.2
1.1
2.06
1.29
u/ml
0.31
11
48
8
36
2.23
1.24
1.6
1.5
21.00
32.72
%
—
8
36
18
108
1.67
1.22
6.4
1.3
—
—
—
0
0
8
37
2.17
1.21
4.3
2.8
17.24
240.89
ug/l
—
8
31
45
333
1.36
1.17
1.2
1.2
—
—
—
0
0
47
351
1.35
1.16
4.2
3.9
—
—
—
0
0
0
36
0.00
1.14
0.0
1.2
—
92.82
—
0
26
272
3019
0.88
1.13
1.9
1.8
1134.08
1174.84
nmol/l
0.35
208
2243
85
1037
0.81
1.11
4.9
4.2
—
—
—
0
0
7
31
2.26
1.10
1.6
1.1
—
17.00
—
0
5
118
997
1.20
1.08
1.6
1.5
—
—
—
0
0
117
990
1.20
1.06
1.9
1.6
—
—
—
0
0
672
6357
1.09
1.06
8.4
5.9
0.04
0.04
e9/l
0.13
595
5349
18
113
1.60
1.05
6.4
1.3
—
—
—
0
0
18
113
1.60
1.05
6.6
1.3
—
—
—
0
0
7
33
2.13
1.05
1.3
1.9
—
—
—
0
0
7
33
2.13
1.05
1.3
1.4
—
—
—
0
0
684
7209
0.91
1.05
4.0
3.3
55.08
56.39
u/l
0.10
642
6604
690
6538
1.09
1.04
8.6
6.1
0.19
0.20
e9/l
0.28
623
5605
670
6341
1.09
1.04
8.4
5.9
0.64
0.62
e9/l
0.76
594
5331
266
2410
1.12
0.97
3.8
3.1
0.81
0.82
mmol/l
0.49
242
2253
23
330
0.69
0.97
1.1
1.1
—
—
—
0
0
949
9838
0.92
0.96
10.3
8.3
78.63
82.43
u/l
2.38
892
9231
0
32
0.00
0.95
0.0
1.1
—
0.73
—
0
19
60
480
1.26
0.94
1.4
1.2
—
—
—
0
0
170
1501
1.15
0.93
3.4
3.2
7.28
5.26
e9/l
0.37
143
1259
160
1409
1.15
0.91
4.1
3.3
211.79
271.25
ng/l
1.59
150
1299
41
314
1.31
0.90
1.4
1.2
—
—
—
0
0
31
414
0.74
0.87
1.6
1.8
3.16
3.43
mmol/l
0.54
19
305
20
136
1.48
0.86
1.2
1.3
140.88
234.40
miu/ml
—
8
43
131
1143
1.16
0.86
5.9
4.3
0.13
0.12
%
0.04
48
351
73
605
1.22
0.86
1.6
2.2
0.00
0.01
estimate
0.50
23
156
17
112
1.52
0.85
6.8
1.3
—
—
—
0
0
153
1353
1.14
0.84
2.1
2.1
0.20
0.20
g/l
0.08
144
1243
131
1146
1.16
0.83
6.6
4.4
0.05
0.16
%
1.00
40
328
11
65
1.70
0.82
1.2
1.0
0.64
0.75
u/ml
—
6
32
452
4803
0.92
0.81
2.4
2.4
—
—
—
0
0
158
1404
1.14
0.81
2.7
2.6
4.44
6.40
ug/l
2.27
132
1203
494
5228
0.92
0.81
5.6
4.3
129.15
126.23
e6/l
0.03
385
3891
117
1020
1.16
0.79
3.9
3.8
7.42
7.42
ph
0.02
102
863
675
6457
1.08
0.77
8.5
6.0
1.86
1.86
e9/l
0.02
608
5591
0
28
0.00
0.76
0.0
3.5
—
14.48
—
0
23
10
59
1.70
0.76
10.4
1.4
—
—
—
0
0
488
4614
1.08
0.75
5.9
4.5
—
—
—
0
0
48
387
1.25
0.75
1.3
1.2
1.53
1.09
u/ml
—
9
29
28
369
0.75
0.74
1.4
1.6
7286.19
14758.36
e6/l
0.77
16
264
412
4374
0.92
0.73
3.1
2.6
—
—
—
0
0
321
3443
0.92
0.72
4.9
3.9
0.02
0.06
estimate
0.62
107
1122
517
5438
0.93
0.71
15.8
12.4
0.00
0.00
e9/l
0.20
425
4384
406
3819
1.08
0.71
8.1
6.6
—
—
—
0
0
57
472
1.21
0.71
5.6
6.8
1.37
1.38
mmol/l
0.03
52
419
248
2284
1.10
0.70
2.8
2.6
21.97
21.64
%
0.13
238
2116
23
169
1.37
0.69
1.7
1.3
25.10
28.08
iu/l
0.16
16
137
118
1042
1.14
0.69
4.0
3.8
5.23
5.18
kpa
0.20
113
986
19
135
1.41
0.69
1.4
1.2
1.90
8.33
u/ml
—
10
60
7
42
1.67
0.68
1.1
2.0
—
—
—
0
0
534
5597
0.93
0.67
3.4
3.0
149.73
153.57
ug/l
0.11
482
5082
144
1292
1.13
0.67
2.7
2.4
38.37
36.07
u/l
0.15
115
1065
30
232
1.30
0.66
1.2
1.2
—
—
—
0
0
72
840
0.85
0.66
1.3
1.2
—
—
—
0
0
40
322
1.25
0.65
2.2
1.5
0.24
0.24
g/l
0.04
40
309
16
224
0.71
0.64
1.6
1.8
184.25
211.86
pmol/l
0.80
16
207
421
3984
1.08
0.64
4.0
3.2
33.23
37.13
u/l
0.75
394
3748
33
260
1.27
0.64
1.5
1.4
1651.78
1533.68
e6/l
0.12
23
183
263
2443
1.09
0.63
2.8
2.6
2.24
2.23
g/l
0.17
248
2242
22
164
1.35
0.62
1.2
1.3
—
—
—
0
0
28
217
1.30
0.62
1.4
1.2
—
—
—
0
0
139
1252
1.12
0.61
2.3
2.2
0.00
0.01
estimate
0.50
30
224
454
4772
0.93
0.61
4.7
3.7
74.43
98.61
e6/l
0.44
377
3774
35
434
0.80
0.61
1.1
1.1
—
155.10
—
0
10
16
113
1.42
0.61
5.4
1.3
—
—
—
0
0
93
1055
0.87
0.60
4.1
3.1
6.06
6.03
ph
0.14
79
782
0
20
0.00
0.60
0.0
1.2
—
1.87
—
0
20
45
373
1.21
0.58
1.6
1.6
15.55
25.61
u/ml
—
10
64
6
35
1.72
0.57
1.2
1.2
—
—
—
0
0
11
73
1.51
0.56
2.5
1.9
—
43.07
—
0
6
29
362
0.80
0.55
1.1
1.2
—
—
—
0
0
158
1445
1.10
0.55
6.7
6.3
11.55
11.59
mmol/l
0.02
153
1379
92
1035
0.88
0.54
1.6
1.5
—
—
—
0
0
6
38
1.58
0.54
2.0
1.4
—
—
—
0
0
9
60
1.50
0.54
1.1
1.2
187.00
367.17
u/l
—
9
54
314
3326
0.93
0.53
3.1
2.5
—
—
—
0
0
39
322
1.22
0.53
4.7
4.7
3.35
2.77
mmol/l
0.53
29
218
322
3406
0.93
0.53
5.3
4.3
86.22
82.96
%
1.54
314
3341
313
2956
1.07
0.52
5.3
4.4
214.94
320.24
ng/l
0.83
270
2563
12
83
1.45
0.51
2.0
2.7
36.50
39.23
%
—
6
50
122
1105
1.11
0.51
1.8
1.5
—
—
—
0
0
68
593
1.15
0.51
2.6
2.1
317.65
494.93
ug/l
0.77
62
560
634
6557
0.95
0.50
8.0
6.6
1.21
1.21
mmol/l
0.05
571
5992
67
586
1.15
0.49
1.4
1.3
—
—
—
0
0
18
136
1.33
0.49
1.3
1.6
22.60
33.25
ng/l
0.57
18
136
611
5902
1.05
0.49
8.8
6.1
58.60
59.07
%
0.42
585
5582
23
181
1.27
0.48
1.0
1.1
—
—
—
0
0
152
1400
1.09
0.47
10.8
7.8
—
—
—
0
0
20
155
1.29
0.46
2.7
2.6
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
13
94
1.39
0.46
1.2
1.2
—
—
—
0
0
175
1626
1.08
0.45
5.0
3.4
2.06
1.91
mmol/l
0.21
148
1369
28
228
1.23
0.45
1.6
1.4
26077.65
78797.60
e6/l
0.99
17
132
29
352
0.82
0.45
2.2
2.4
91.70
81.48
ug/min
0.05
18
209
479
4974
0.95
0.44
5.3
4.4
0.02
0.04
estimate
0.66
109
1204
23
184
1.25
0.43
2.4
2.2
0.75
1.16
g/24h
0.56
15
107
422
4050
1.06
0.43
2.5
2.3
2.88
2.98
mg/l
0.40
362
3440
220
2070
1.07
0.42
6.0
5.4
1.07
1.04
mmol/l
0.73
200
1899
8
57
1.41
0.42
1.0
1.0
—
—
—
0
0
6
95
0.63
0.42
3.0
2.5
—
—
—
0
0
276
2619
1.06
0.41
2.8
2.6
11.91
11.80
umol/l
0.10
265
2423
0
15
0.00
0.41
0.0
1.2
—
7.63
—
0
9
0
15
0.00
0.41
0.0
2.7
—
75.86
—
0
5
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
16
123
1.30
0.40
1.3
1.1
—
—
—
0
0
20
159
1.26
0.40
3.1
4.3
—
—
—
0
0
19
150
1.27
0.40
1.1
1.1
230.74
98.13
iu/ml
—
5
24
7
103
0.68
0.39
2.4
2.9
—
—
—
0
0
460
4438
1.05
0.39
8.2
5.8
—
—
—
0
0
5
36
1.39
0.38
1.2
1.2
1.09
1.07
ratio
—
5
29
427
4429
0.95
0.38
1.8
1.8
19.72
19.88
nmol/l
0.07
360
3718
9
67
1.35
0.38
1.0
1.1
—
—
—
0
0
32
376
0.85
0.37
18.8
13.7
—
—
—
0
0
5
37
1.35
0.37
1.2
1.1
—
—
—
0
0
5
37
1.35
0.37
1.2
1.1
—
—
—
0
0
5
37
1.35
0.37
1.2
1.1
—
—
—
0
0
547
5309
1.04
0.36
4.3
3.8
6.38
6.26
ph
1.57
290
2916
5
77
0.65
0.35
1.0
1.5
—
—
—
0
0
26
217
1.20
0.35
1.5
1.6
—
—
—
0
0
37
320
1.16
0.34
2.3
2.7
15.97
15.79
%
0.15
37
314
295
3080
0.95
0.34
3.3
3.1
2.46
2.46
mmol/l
0.14
262
2744
13
167
0.78
0.34
1.1
1.2
1.46
1.53
g/l
0.44
13
167
149
1397
1.07
0.33
4.2
2.9
4.16
4.40
kpa
0.88
144
1355
6
45
1.33
0.33
1.2
1.8
—
—
—
0
0
474
4889
0.96
0.33
3.5
3.5
2.34
2.35
mmol/l
0.93
427
4378
173
1632
1.07
0.33
3.7
4.0
67.59
20.95
ug/l
0.48
150
1357
182
1720
1.07
0.33
1.2
1.3
—
—
—
0
0
610
5946
1.04
0.33
9.1
6.2
9.19
9.18
%
0.03
578
5513
395
4088
0.96
0.33
4.5
3.6
0.48
0.51
e6/l
0.12
319
3134
164
1548
1.07
0.31
2.5
2.5
67.02
67.04
e9/l
0.00
125
1169
178
1685
1.06
0.31
4.9
3.5
7.37
7.38
ph
0.84
117
1022
60
662
0.90
0.30
2.1
2.1
—
—
—
0
0
7
54
1.30
0.30
1.9
4.1
51.64
51.07
%
—
7
48
616
6021
1.04
0.28
8.9
6.2
25.41
25.33
%
0.06
589
5659
163
1718
0.94
0.28
1.4
1.4
—
—
—
0
0
9
118
0.76
0.27
1.8
1.2
—
—
—
0
0
728
7143
1.03
0.27
12.0
9.2
4.41
4.33
e9/l
0.34
641
6138
265
2551
1.05
0.26
3.8
3.3
1.51
1.16
e6/l
0.76
161
1439
42
468
0.89
0.26
1.2
1.3
—
—
—
0
0
81
751
1.08
0.26
1.3
1.3
—
—
—
0
0
5
71
0.70
0.26
1.0
1.2
142.40
137.68
nmol/l
—
5
71
5
74
0.67
0.26
1.0
1.9
—
—
—
0
0
111
1177
0.94
0.24
2.5
2.6
—
—
—
0
0
9
77
1.17
0.24
1.8
1.1
—
—
—
0
0
22
254
0.86
0.23
1.2
1.4
—
—
—
0
0
14
115
1.22
0.23
7.7
2.2
7.27
8.12
mmol/l
0.70
14
115
35
313
1.12
0.23
1.2
1.2
38.00
104.00
titre
—
5
25
13
106
1.23
0.23
1.4
1.2
—
—
—
0
0
7
93
0.75
0.22
3.4
2.4
8.47
7.23
mmol/l
—
7
58
7
95
0.74
0.22
1.6
1.2
—
—
—
0
0
218
2101
1.04
0.22
1.8
1.5
3.00
2.71
g/l
0.67
132
1192
17
144
1.18
0.22
1.1
1.2
0.18
0.19
nmol/l
0.20
11
116
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.30
—
0
5
0
11
0.00
0.21
0.0
1.0
—
26.70
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
5.2
—
0.31
—
0
10
0
10
0.00
0.21
0.0
1.5
—
1.41
—
0
5
23
262
0.88
0.21
1.7
1.8
2.37
27.37
iu/l
0.54
11
99
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
15
126
1.19
0.21
1.1
1.1
—
—
—
0
0
665
6760
0.97
0.21
5.1
4.3
0.03
0.22
estimate
0.44
140
1416
0
13
0.00
0.21
0.0
1.0
—
76.31
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
17
145
1.17
0.20
2.4
2.0
3.80
1.56
u/field
—
10
75
0
14
0.00
0.20
0.0
1.6
—
7.40
—
0
8
0
14
0.00
0.20
0.0
1.0
—
0.56
—
0
6
51
551
0.92
0.19
4.8
4.0
24.88
24.97
mmol/l
0.06
45
496
25
222
1.13
0.19
1.7
1.4
—
—
—
0
0
13
109
1.19
0.18
1.3
1.4
7.41
7.39
ph
—
5
82
652
6618
0.98
0.18
5.0
4.3
0.00
0.00
estimate
0.50
134
1461
604
5944
1.03
0.18
9.1
6.2
0.66
0.65
%
0.20
574
5505
11
132
0.83
0.18
1.0
1.1
—
—
—
0
0
17
147
1.16
0.18
1.1
1.1
—
—
—
0
0
7
59
1.19
0.18
4.9
2.8
766.43
1523.47
u/ml
—
7
59
131
1366
0.96
0.18
3.6
4.6
7.37
7.36
ph
0.40
90
974
15
174
0.86
0.17
2.9
2.1
—
—
—
0
0
307
2994
1.03
0.17
5.6
4.5
1.02
1.02
kg/l
0.14
212
2044
91
864
1.06
0.17
4.7
2.5
1.21
1.15
%
0.26
91
857
108
1131
0.95
0.17
2.0
2.1
383.27
383.19
nmol/l
0.00
96
1032
5
66
0.76
0.17
1.6
2.9
—
—
—
0
0
37
401
0.92
0.16
3.6
3.7
2.14
1.56
index
0.35
21
225
47
438
1.08
0.16
2.2
1.8
20.74
21.20
s
0.30
42
407
391
3835
1.03
0.15
5.1
4.4
0.00
0.00
estimate
0.78
122
1286
663
6716
0.98
0.15
5.1
4.3
19.44
3.39
estimate
0.59
145
1504
6
80
0.75
0.15
1.0
1.2
—
4.50
—
0
18
559
5672
0.98
0.15
4.7
4.5
39.08
77.32
ng/l
1.78
440
4513
9
82
1.10
0.15
1.8
1.1
—
—
—
0
0
56
594
0.94
0.14
2.7
3.2
137.26
7167.28
u/ml
0.90
49
514
11
93
1.18
0.14
2.7
2.2
—
—
—
0
0
66
696
0.95
0.14
4.1
2.8
—
—
—
0
0
28
256
1.10
0.14
1.6
1.3
25.85
70.85
e6/l
0.56
20
192
719
7270
0.98
0.14
8.7
7.3
1.21
1.21
mmol/l
0.29
615
6203
311
3174
0.98
0.14
1.7
1.8
71008863.95
9714497.33
pmol/l
0.59
238
2553
602
5944
1.02
0.14
9.0
6.1
2.82
2.81
%
0.03
570
5512
347
3535
0.98
0.13
3.4
3.0
349.96
363.63
umol/l
1.53
295
3001
294
2997
0.98
0.12
3.6
3.2
523.06
536.81
mosm/kgh2o
0.65
261
2631
12
104
1.15
0.12
1.0
1.2
—
—
—
0
0
10
85
1.18
0.12
1.0
1.1
—
—
—
0
0
28
259
1.08
0.11
1.6
1.3
29.48
690.58
e6/l
0.87
21
202
436
4420
0.98
0.11
2.7
2.2
226.95
227.76
u/l
0.01
410
4155
122
1183
1.03
0.11
4.0
3.7
1.22
1.22
mmol/l
0.21
104
1000
20
182
1.10
0.11
1.1
1.0
—
—
—
0
0
23
250
0.92
0.11
1.3
1.7
—
—
—
0
0
509
5151
0.98
0.11
3.8
3.4
1813.81
1953.16
ng/l
0.27
449
4491
54
514
1.05
0.11
3.6
2.9
308.57
303.33
mg/l
0.02
28
206
175
1792
0.97
0.11
1.3
1.3
17.99
14.22
u/ml
0.30
74
618
25
270
0.92
0.10
1.6
2.0
0.96
0.84
%
0.67
19
197
16
144
1.11
0.10
1.1
1.2
—
—
nmol/l
—
0
0
88
850
1.04
0.10
4.7
2.5
0.60
0.63
%
0.29
88
844
23
212
1.09
0.10
1.7
1.4
—
—
—
0
0
41
388
1.06
0.10
1.4
1.6
0.30
0.35
mg/l
0.26
21
172
47
447
1.05
0.10
3.4
3.4
0.78
0.84
nmol/l
0.50
41
371
720
7142
1.01
0.09
7.4
6.5
10.81
12.44
umol/l
4.74
681
6774
13
116
1.12
0.09
1.7
1.2
—
—
—
0
0
13
116
1.12
0.09
1.4
1.2
—
—
—
0
0
230
2340
0.98
0.09
1.3
1.2
1.15
1.66
u/ml
0.70
68
582
634
6394
0.99
0.09
5.4
5.1
34.22
34.44
g/l
0.42
580
5944
25
233
1.07
0.09
1.5
1.2
35.21
62.10
u/ml
—
7
23
347
3427
1.02
0.08
3.5
2.8
6.45
4.81
e6/l
1.10
322
3136
272
2681
1.02
0.08
2.0
1.6
1.35
1.56
mg/l
0.47
215
2125
5
63
0.79
0.08
2.0
2.2
1063.80
978.12
e6/l
—
5
49
7
66
1.06
0.08
1.3
1.0
—
—
—
0
0
28
297
0.94
0.08
1.2
1.1
—
—
—
0
0
41
429
0.95
0.07
1.4
1.4
—
—
—
0
0
26
276
0.94
0.07
1.9
1.6
—
—
—
0
0
70
722
0.97
0.07
4.5
3.9
—
—
—
0
0
112
1146
0.98
0.07
1.4
1.4
—
—
—
0
0
16
147
1.09
0.07
1.1
1.2
—
—
—
0
0
420
4240
0.99
0.07
2.8
2.6
56.90
80.20
u/l
0.65
391
3894
153
1558
0.98
0.07
2.4
2.7
6.33
8.89
umol/l
2.79
129
1393
9
100
0.90
0.06
1.0
1.2
103.67
98.59
pmol/l
—
9
100
142
1395
1.02
0.06
1.3
1.3
—
—
—
0
0
14
152
0.92
0.06
1.5
2.1
—
—
—
0
0
12
109
1.10
0.06
1.0
1.1
—
—
—
0
0
12
109
1.10
0.06
1.0
1.1
—
—
—
0
0
42
405
1.04
0.05
1.4
1.5
252.94
265.87
ug/g
0.17
25
240
15
139
1.08
0.05
4.7
3.4
19.40
11.40
index
—
10
78
562
5654
0.99
0.05
2.6
2.4
80.27
79.25
nmol/l
0.35
495
4949
237
2396
0.99
0.05
4.1
3.4
2.40
1.89
e6/l
0.49
127
1274
23
242
0.95
0.05
1.0
1.1
—
—
—
0
0
464
4670
0.99
0.05
4.4
3.6
—
—
—
0
0
26
248
1.05
0.05
1.9
1.9
1.53
1.76
mmol/l
0.80
26
242
119
1172
1.02
0.04
3.7
3.7
90.31
98.08
ng/l
0.47
103
990
56
546
1.03
0.04
4.4
3.4
2.84
3.88
ratio
0.35
33
328
76
774
0.98
0.03
4.3
3.9
1.02
1.02
ratio
0.92
68
712
332
3341
0.99
0.03
3.9
3.4
0.08
0.08
0.01
13
126
38
391
0.97
0.03
1.9
1.5
—
—
—
0
0
31
320
0.97
0.03
2.0
2.8
34.38
33.49
umol/l
0.05
26
277
43
420
1.02
0.02
4.3
4.7
—
—
—
0
0
144
1427
1.01
0.02
2.9
2.8
65.90
65.98
g/l
0.04
131
1296
192
1907
1.01
0.02
1.3
1.3
60.23
37.05
iu/ml
0.49
59
592
441
4425
1.00
0.02
5.2
4.2
7.40
7.40
ph
1.07
345
3236
202
2032
0.99
0.02
2.6
2.4
1.84
1.79
%
0.34
174
1798
77
761
1.01
0.01
2.4
2.5
—
—
—
0
0
40
392
1.02
0.01
1.9
1.6
—
—
—
0
0
60
593
1.01
0.01
1.3
1.2
—
—
—
0
0
59
597
0.99
0.01
4.8
3.6
81.41
72.51
mg/l
0.06
49
512
59
597
0.99
0.01
4.8
3.6
60.58
62.15
mg/l
0.03
49
510
20
195
1.03
0.00
1.8
1.3
16.91
8.51
u/l
1.11
12
153
14
141
0.99
0.00
1.2
1.2
—
—
—
0
0
17
169
1.01
0.00
1.1
1.2
0.66
11.28
nmol/l
0.50
17
160
32
325
0.98
0.00
4.2
3.7
30.36
29.13
mg/l
0.06
23
237
123
1228
1.00
0.00
2.4
2.2
197.44
141.28
ug/g
0.76
98
969
10
98
1.02
0.00
2.4
1.7
116.82
118.14
ng/l
—
10
98
12
117
1.03
0.00
1.1
1.2
—
—
—
0
0
19
193
0.98
0.00
1.1
1.1
—
—
—
0
0
81
813
1.00
0.00
1.9
1.7
1.44
1.55
g/l
0.53
67
703
128
1275
1.00
0.00
3.3
2.6
0.63
0.54
e6/l
0.18
121
1228
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
80
1.00
-0.00
3.3
1.6
—
—
—
0
0
9
90
1.00
-0.00
2.1
2.2
3.08
1.93
ug/l
—
9
74
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
99
0.91
-0.00
1.1
1.8
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.1
—
—
—
0
0
9
91
0.99
-0.00
2.3
2.2
4.17
3.20
ug/l
—
9
86
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.6
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
16.6
—
224.14
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.5
—
0.21
—
0
8
5
54
0.93
-0.00
2.4
1.4
29.60
29.56
umol/l
—
5
49
0
5
0.00
-0.00
0.0
1.4
—
103.80
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
288.58
—
0
5

Mortality – FinRegistry

Association

Association between endpoint AB1_RESP_TUBERCU_NONCONF and mortality.

Females

Parameter HR [95% CI] p-value
AB1_RESP_TUBERCU_NONCONF 2.647 [2.24, 3.13] < 0.001
Birth year 0.993 [0.98, 1.0] 0.118

During the follow-up period (1.1.1998 — 31.12.2019), 641 out of 1245 females with AB1_RESP_TUBERCU_NONCONF died.

Males

Parameter HR [95% CI] p-value
AB1_RESP_TUBERCU_NONCONF 2.682 [2.28, 3.16] < 0.001
Birth year 0.988 [0.98, 1.0] 0.014

During the follow-up period (1.1.1998 — 31.12.2019), 1179 out of 1955 males with AB1_RESP_TUBERCU_NONCONF died.

Mortality risk

Mortality risk for people of age

years, who have AB1_RESP_TUBERCU_NONCONF.

N-year risk Females Males
1 0.247% 0.493%
5 1.684% 3.329%
10 3.933% 8.096%
15 6.764% 15.062%
20 12.124% 24.76%

Relationships between endpoints

Index endpoint: AB1_RESP_TUBERCU_NONCONF – Respiratory tuberculosis, not confirmed

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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