Respiratory tuberculosis

TBC_RESP

pulmonary tuberculosis: A bacterial infection that affects the lungs and is caused by Mycobacterium tuberculosis. Most patients with tuberculosis do not have symptoms (latent tuberculosis) and are not contagious. When signs and symptoms occur (active tuberculosis), patients become contagious. The signs and symptoms include chronic cough with blood-tinged sputum, night sweats, fever, fatigue, and weight loss.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2561

6. Filter based on genotype QC (FinnGen only)

2253

Control definitions (FinnGen only)

Control exclude
IBD_TUBERCULOSIS

Extra metadata

First used in FinnGen datafreeze
DF2

Similar endpoints

List of similar endpoints to Respiratory tuberculosis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 34910 13713 20113
Only index persons 17505 8163 9342
Unadjusted period prevalence (%)
Whole population 0.51 0.39 0.56
Only index persons 0.33 0.30 0.36
Median age at first event (years)
Whole population 53.02 52.55 53.15
Only index persons 42.73 41.60 43.72

-FinnGen-

Key figures

All Female Male
Number of individuals 2253 784 1469
Unadjusted period prevalence (%) 0.54 0.28 0.67
Median age at first event (years) 45.86 37.63 50.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2344
Matched controls
23440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
+∞
307.7
396
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
307.7
304
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
47.8
301.8
177
40
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
277.8
261
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
231.1
218
*
01220
ICD-8 Finland
Other respiratory tuberculosis, Pleurisy with effusion without mention of cause
+∞
216.0
204
*
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
2001.9
183.7
176
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.0
163.5
573
1752
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.5
163.3
473
1257
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
153.9
146
*
01210
ICD-8 Finland
Other respiratory tuberculosis, Tuberculosis pleurae, pleuritis exsudativa tuberculosa
+∞
131.5
125
*
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
36.8
86.6
54
15
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
21.9
86.1
64
30
A70
ICPC
Tuberculosis
284.2
81.1
82
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
79.4
561
2494
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
+∞
78.6
75
*
0110K, ,
ICD-8 Finland
+∞
75.4
72
*
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
+∞
73.3
70
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
69.1
66
*
0110X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, EPÄILTY]
+∞
64.9
62
*
A16.5
ICD-10 Finland
Tuberculous pleurisy, without mention of bacteriological or histological confirmation
+∞
59.6
57
*
R03BB04
ATC
tiotropium bromide; inhalant
2.5
57.6
438
1988
A15.6
ICD-10 Finland
Tuberculous pleurisy, confirmed bacteriologically and histologically
+∞
57.5
55
*
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
10.4
54.8
61
60
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
508.6
50.6
50
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
50.6
963
6197
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.8
48.8
259
979
A16.1
ICD-10 Finland
Tuberculosis of lung, bacteriological and histological examination not done
477.2
47.5
47
*
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
12.7
46.1
45
36
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.3
45.0
179
572
0110J, ,
ICD-8 Finland
+∞
44.9
43
*
A15.3
ICD-10 Finland
Tuberculosis of lung, confirmed by unspecified means
+∞
44.9
43
*
TGC00
NOMESCO Finland
Bronchial lavation
4.3
42.5
111
265
A16.9
ICD-10 Finland
Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
+∞
41.8
40
*
0120X
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, EPÄILTY]
+∞
38.6
37
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
37.6
559
3251
1240
FHL
Bronchoscopy
4.5
36.8
90
204
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.0
35.9
165
574
0110A, ,
ICD-8 Finland
+∞
35.5
34
*
R03DA04
ATC
theophylline; systemic, rectal
2.4
34.5
271
1231
A15.7
ICD-10 Finland
Primary respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
33.4
32
*
H02AB06
ATC
prednisolone; systemic
1.7
32.3
1131
8373
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
30.8
364
1941
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
7.7
30.6
43
57
J01MA14
ATC
moxifloxacin; systemic
2.2
30.3
267
1271
01106
ICD-8 Finland
Pulmonary tuberculosis, Pulmonum alia sive NUD
+∞
30.3
29
*
01104
ICD-8 Finland
Pulmonary tuberculosis, Tuberculoma pulmonum
+∞
30.3
29
*
R03BB01
ATC
ipratropium bromide; inhalant
2.4
29.3
214
940
0119X
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, EPÄILTY]
+∞
29.2
28
*
0112A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, BAKTERIOL.VARMA]
+∞
29.2
28
*
J47
ICD-10 Finland
Bronchiectasis
3.9
28.5
85
224
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.3
28.0
228
1049
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.1
27.4
270
1343
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
27.2
162
646
01109
ICD-8 Finland
Pulmonary tuberculosis, Unspecified
+∞
27.1
26
*
R03AC12
ATC
salmeterol; inhalant
2.5
26.8
182
772
J96.1
ICD-10 Finland
Chronic respiratory failure
3.1
26.4
113
377
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.6
26.0
154
612
R03AC02
ATC
salbutamol; inhalant
1.6
25.5
1116
8549
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.7
25.5
83
233
01297
ICD-8 Finland
Other respiratory tuberculosis, Suspecta
+∞
25.0
24
*
A15.8
ICD-10 Finland
Other respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
24.0
23
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
22.8
387
2312
R04.2
ICD-10 Finland
Haemoptysis
2.6
22.6
130
509
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
34.1
21.1
27
8
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
20.5
166
760
A15.4
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, confirmed bacteriologically and histologically
+∞
19.8
19
*
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
2.7
18.5
100
380
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.0
18.4
81
275
01710
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum colli
+∞
17.7
17
*
M05BA04
ATC
alendronic acid; oral
1.9
17.4
232
1279
H02AB07
ATC
prednisone; oral
1.7
16.6
346
2176
48609
ICD-8 Finland
Pneumonia, unspecified
4.1
16.6
45
111
48601
ICD-8 Finland
More specifically, unspecified pneumonia and the pleural irritation caused by it
6.7
16.6
26
39
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
16.4
409
2693
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
5.2
16.3
33
64
J45.8
ICD-10 Finland
Mixed asthma
2.7
16.1
87
331
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
60.4
15.8
18
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.2
15.7
134
627
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
15.7
166
845
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
15.6
15
*
0119A
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, BAKTERIOLOG. VARMA]
+∞
15.6
15
*
0120B
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, HISTOLOGISESTI VARMENNETTU]
+∞
15.6
15
*
R03BA01
ATC
beclometasone; inhalant
1.7
15.6
310
1925
51120
ICD-8 Finland
Pleurisy, Other specified forms of effusion, except tuberculous
22.2
15.5
22
10
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.3
15.4
119
535
R05CB01
ATC
acetylcysteine; inhalant, oral
3.0
15.4
68
232
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
3.4
14.4
52
157
J43.9
ICD-10 Finland
Emphysema, unspecified
2.9
14.3
68
242
L04AX01
ATC
azathioprine; systemic
2.5
14.2
86
346
J01FA06
ATC
roxithromycin; oral
1.4
14.0
817
6399
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.3
13.8
52
161
0118X
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, EPÄILTY]
+∞
13.6
13
*
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.8
13.5
69
255
L04AA13
ATC
[U] leflunomide
3.1
13.0
53
173
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
12.8
1055
8727
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.8
12.6
61
219
13599
ICD-8 Finland
Sarcoidosis, Unspecified
6.0
12.6
22
37
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
70.3
12.6
14
*
01292
ICD-8 Finland
Other respiratory tuberculosis, Lymphonodorum tracheobronchialium et mediastini
+∞
12.5
12
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.1
12.4
125
625
R03BB02
ATC
oxitropium bromide; inhalant
3.2
12.3
48
152
J01MA12
ATC
levofloxacin; systemic
1.5
12.2
448
3200
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
12.1
406
2845
R03AC13
ATC
formoterol; inhalant
2.0
12.1
130
666
Z20.1
ICD-10 Finland
Contact with and exposure to tuberculosis
9.3
12.0
24
26
P01BA02
ATC
hydroxychloroquine; oral
1.9
11.8
149
807
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
3.0
11.7
52
178
48509
ICD-8 Finland
Bronchopneumonia, unspecified
4.1
11.6
31
76
0112X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, EPÄILTY]
+∞
11.5
11
*
J46
ICD-10 Finland
Status asthmaticus
2.6
11.3
66
262
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
2.8
11.3
57
210
N05CD07
ATC
temazepam; oral
1.5
11.1
353
2444
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
2.7
11.1
57
212
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
11.0
919
7562
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
10.8
165
948
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
10.7
219
1366
01908
ICD-8 Finland
Late effects of tuberculosis, Sequelae aliae o tuberculosis organorum respirationis
21.6
10.7
15
7
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
3.5
10.6
35
100
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.2
10.5
84
384
L01BA01
ATC
methotrexate; systemic
2.3
10.5
78
346
XG410
NOMESCO Finland
Flow-volume spirometry
2.1
10.5
96
464
03199
ICD-8 Finland
Other diseases due to Mycobacteria, Other and unspecified
+∞
10.4
10
*
01103
ICD-8 Finland
Pulmonary tuberculosis, Bronchialis
+∞
10.4
10
*
A18.0
ICD-10 Finland
Tuberculosis of bones and joints
+∞
10.4
10
*
A31.9
ICD-10 Finland
Mycobacterial infection, unspecified
18.9
10.3
15
8
A98
ICPC
Health maint/preventive medicine
0.7
10.3
1531
16823
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
3.1
10.2
42
138
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
3.8
10.0
30
80
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
3.8
10.0
30
80
R03BA02
ATC
budesonide; inhalant
1.5
10.0
342
2400
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
4.1
10.0
27
67
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.9
9.9
131
720
A07EC01
ATC
sulfasalazine; oral, rectal
1.8
9.7
147
843
J01AA02
ATC
doxycycline; systemic
1.3
9.7
1613
14562
A02BA02
ATC
ranitidine; systemic
1.4
9.7
463
3465
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
4.3
9.6
24
56
R95
ICPC
Chron obstructive pulmonary disease
2.1
9.6
86
413
R03AC03
ATC
terbutaline; inhalant
1.6
9.5
258
1723
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
2.8
9.5
47
172
5111B
ICD-9 Finland
Pleurisy, With effusion, with mention of a bacterial cause other than tuberculosis[PLEURITIS EXSUDATIVA ALIA DEFINITA]
30.1
9.4
12
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
9.4
9
*
0110B, ,
ICD-8 Finland
+∞
9.4
9
*
0120A
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, BAKTERIOLOGISESTI VARMA]
+∞
9.4
9
*
A16.8
ICD-10 Finland
Other respiratory tuberculosis, without mention of bacteriological or histological confirmation
+∞
9.4
9
*
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
3.5
9.3
31
89
132
Kela drug reimbursment
Sarcoidosis
4.1
9.2
25
62
N05BA02
ATC
chlordiazepoxide; systemic
2.5
9.1
57
234
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
9.1
399
2936
R99
ICPC
Respiratory disease other
2.7
8.9
45
166
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
3.4
8.9
31
92
51899
ICD-8 Finland
Bronchiectasis
8.0
8.8
19
24
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
3.2
8.7
34
109
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
16.3
8.5
13
8
D86.0
ICD-10 Finland
Sarcoidosis of lung
3.4
8.5
29
85
Z22.30
ICD-10 Finland
Latent tuberculosis
27.6
8.5
11
*
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
4.9
8.4
18
37
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.4
598
4765
01202, ,
ICD-8 Finland
+∞
8.3
8
*
0118A
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, BAKTERIOLOG.VARMA]
+∞
8.3
8
*
J94.9
ICD-10 Finland
Pleural condition, unspecified
4.0
8.3
23
58
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
8.2
60
266
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
8.1
341
2488
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.1
897
7589
13597
ICD-8 Finland
Sarcoidosis, Suspecta
4.1
8.0
21
51
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
2.2
7.8
64
297
Y0499
ICD-8 Finland
Investigation of respiratory system
2.7
7.8
39
144
51109
ICD-8 Finland
Pleurisy, Sicca NUD
15.1
7.7
12
8
A10BA02
ATC
metformin; oral
0.7
7.6
408
5261
L88
ICPC
Rheumatoid/seropositive arthritis
2.1
7.6
72
354
I10
ICD-10 Finland
Essential (primary) hypertension
0.8
7.6
1126
12674
49300
ICD-8 Finland
Asthma, bronchiale
2.2
7.6
58
262
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
2.9
7.5
33
113
A02BC01
ATC
omeprazole; systemic
1.3
7.5
582
4679
R05
ICD-10 Finland
Cough
1.4
7.5
368
2758
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.0
7.5
78
397
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
2.1
7.4
67
323
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
13.4
7.4
12
9
Z2446
NOMESCO Finland
Social worker
1.7
7.4
125
743
F10.20
ICD-10 Finland
Alcohol dependence currently independent
2.7
7.3
38
143
A16.4
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation
+∞
7.3
7
*
A15.5
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, confirmed bacteriologically and histologically
+∞
7.3
7
*
A15
ICD-10 Finland
Respiratory tuberculosis, bacteriologically and histologically confirmed
+∞
7.3
7
*
A18.8
ICD-10 Finland
Tuberculosis of other specified organs
+∞
7.3
7
*
49109
ICD-8 Finland
Chronic bronchitis, Unspecified
4.2
7.3
19
46
7863A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Haemoptysis
3.8
7.3
21
55
H02AB04
ATC
methylprednisolone; systemic
1.4
7.2
281
2019
A31.89
ICD-10 Finland
Other mycobacterial infections
30.1
7.1
9
*
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
2.7
7.1
37
140
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
7.1
218
3095
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
3.0
7.0
29
96
R50.9
ICD-10 Finland
Fever, unspecified
1.4
7.0
311
2289
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
2.2
6.9
55
253
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
2.4
6.9
45
190
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
6.8
133
822
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.5
6.8
39
155
Y3419
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Inactive pulmonary tuberculosis, which is known to have been inactive
40.2
6.8
8
*
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
2.7
6.7
35
132
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
2.4
6.5
41
170
R03AK08
ATC
formoterol and beclometasone; inhalant
1.9
6.4
73
384
J94.8
ICD-10 Finland
Other specified pleural conditions
2.3
6.4
47
209
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.0
6.4
62
309
A02BA03
ATC
famotidine; systemic
1.8
6.3
98
568
J86.9
ICD-10 Finland
Pyothorax without fistula
2.8
6.3
29
103
A18.3
ICD-10 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands
+∞
6.3
6
*
A16.3
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation
+∞
6.3
6
*
0116X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA, EPÄILTY]
+∞
6.3
6
*
M49.0*A18.0
ICD-10 Finland
Tuberculosis of spine
+∞
6.3
6
*
01230
ICD-8 Finland
Other respiratory tuberculosis, Tuberculous laryngitis
+∞
6.3
6
*
01105
ICD-8 Finland
Pulmonary tuberculosis, Disseminata pulmonum
+∞
6.3
6
*
A19.1
ICD-10 Finland
Acute miliary tuberculosis of multiple sites
+∞
6.3
6
*
0116A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA,BAKTER.VARMA]
+∞
6.3
6
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.2
603
4983
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
2.8
6.2
29
104
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.9
6.1
72
383
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
2.1
6.1
53
253
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
3.1
6.0
24
78
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
2.5
6.0
36
146

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
107
288
3.85
34.86
6.7
2.5
—
—
—
0
0
345
1891
1.97
26.80
1.9
1.6
—
—
—
0
0
89
284
3.22
22.40
3.7
2.4
—
—
—
0
0
70
237
3.01
16.01
1.6
1.5
—
—
—
0
0
70
237
3.01
16.01
1.6
1.5
—
—
—
0
0
70
237
3.01
16.01
1.6
1.5
—
—
—
0
0
70
237
3.01
16.01
1.6
1.5
—
—
—
0
0
23
37
6.27
13.74
1.3
1.5
—
—
—
0
0
310
2054
1.59
11.91
2.0
1.4
—
—
—
0
0
24
48
5.04
11.47
1.1
1.3
—
—
—
0
0
57
211
2.74
11.17
1.4
1.3
27.22
14.55
u/l
2.59
51
194
24
52
4.65
10.47
2.9
2.2
—
—
—
0
0
1409
15686
0.74
10.46
6.1
6.1
2.51
2.52
mmol/l
0.14
1286
14244
387
2796
1.46
9.80
2.5
2.1
—
—
—
0
0
1575
17189
0.74
9.64
41.0
29.5
7.34
6.98
e9/l
3.79
1526
16656
1574
17179
0.75
9.64
41.0
29.5
249.47
239.97
e9/l
5.59
1528
16718
1575
17186
0.75
9.61
41.1
29.7
130.14
132.01
g/l
4.83
1546
16892
1377
15310
0.76
9.59
5.3
5.3
4.42
4.40
mmol/l
0.27
1257
13971
1575
17183
0.75
9.57
41.9
30.0
39.24
39.40
%
0.57
1544
16873
1575
17183
0.75
9.57
40.8
29.4
30.35
30.45
pg
1.35
1545
16884
1575
17183
0.75
9.57
40.9
29.5
4.33
4.37
e12/l
2.16
1522
16652
1575
17180
0.75
9.53
40.8
29.4
91.86
91.81
fl
0.14
1545
16882
1365
15160
0.76
9.18
5.3
5.2
1.45
1.42
mmol/l
1.47
1238
13702
119
659
1.85
8.84
1.4
1.2
—
—
—
0
0
355
2575
1.45
8.75
8.1
7.0
1.33
0.98
mmol/l
0.93
303
2085
356
2588
1.44
8.66
8.0
7.1
5.11
5.07
kpa
0.30
340
2471
356
2588
1.44
8.66
8.0
7.1
11.47
11.65
kpa
0.21
341
2473
57
243
2.38
8.45
1.8
1.7
0.87
0.87
g/l
0.01
39
195
200
1296
1.59
8.40
3.1
2.9
10.47
10.88
g/l
0.53
190
1183
1570
17044
0.76
8.40
35.6
26.2
86.12
85.84
umol/l
0.08
1539
16736
288
2025
1.48
8.32
1.4
1.3
548.92
484.36
titre
0.26
65
459
1315
14573
0.78
8.02
4.5
4.4
1.27
1.27
mmol/l
0.10
1180
13033
1412
15506
0.78
7.98
5.6
5.6
6.03
6.09
mmol/l
0.92
1277
13853
1485
16194
0.77
7.87
23.6
18.0
—
—
—
0
0
349
2575
1.42
7.79
8.2
7.1
7.42
7.42
ph
0.20
208
1454
1015
8803
1.27
7.28
9.7
5.9
0.04
0.04
e9/l
0.14
891
7435
1012
8779
1.27
7.22
9.7
5.9
0.64
0.62
e9/l
1.52
886
7410
1553
16776
0.78
7.15
33.0
24.2
4.01
4.01
mmol/l
0.03
1519
16356
28
91
3.10
7.01
1.5
2.1
754.43
555.39
e6/l
0.43
23
74
161
1036
1.59
6.99
2.0
1.9
1.37
1.51
g/l
0.20
151
937
81
430
1.92
6.92
1.8
2.1
11.87
13.64
mg/l
0.61
72
396
1554
16759
0.78
6.86
32.7
24.0
139.31
139.59
mmol/l
3.72
1522
16363
1037
9062
1.26
6.83
10.2
6.1
0.19
0.20
e9/l
0.19
923
7779
1389
15166
0.79
6.75
6.9
7.1
40.16
40.41
mmol/mol
0.46
1270
13883
76
401
1.93
6.62
1.5
1.5
36.63
30.68
g/l
3.25
71
363
725
6106
1.27
6.42
10.2
5.9
—
—
—
0
0
1551
16686
0.79
6.39
17.5
12.8
24.86
25.14
u/l
0.09
1501
16055
35
136
2.60
6.37
1.6
1.9
1388.83
1100.08
e6/l
0.52
30
121
57
277
2.08
6.26
1.5
1.4
5.78
6.44
mmol/l
0.96
52
263
57
278
2.08
6.20
1.3
1.2
—
—
—
0
0
1019
8956
1.24
6.17
9.8
6.0
1.99
1.85
e9/l
0.43
908
7764
645
7633
0.79
6.17
5.1
5.9
4.10
4.33
ug/l
0.06
565
6753
346
4446
0.74
6.16
3.1
3.5
0.87
0.84
ug/l
0.11
237
3104
419
3300
1.33
6.15
4.3
3.1
0.81
0.82
mmol/l
1.15
390
3079
309
2323
1.38
6.14
8.8
7.3
94.81
95.11
%
0.37
296
2241
294
2200
1.38
6.00
2.2
1.8
—
—
—
0
0
147
968
1.55
5.81
1.7
1.4
—
—
—
0
0
401
4997
0.76
5.69
3.2
3.5
—
—
—
0
0
28
103
2.74
5.69
1.6
1.3
1.53
0.61
u/ml
0.43
21
59
134
873
1.57
5.57
1.6
1.3
217.14
242.83
u/ml
0.15
121
805
932
8183
1.23
5.50
10.0
6.1
58.60
58.92
%
0.32
892
7760
57
292
1.98
5.47
1.6
1.6
—
—
—
0
0
934
8214
1.23
5.40
10.4
6.3
9.23
9.16
%
0.25
886
7639
279
2118
1.36
5.21
9.4
7.9
119.63
119.70
g/l
0.02
271
2072
1367
14783
0.82
5.19
5.5
5.2
1.92
2.03
mu/l
2.91
1239
13329
730
6288
1.23
5.07
6.3
4.5
—
—
—
0
0
194
1392
1.43
5.06
7.9
6.9
24.90
24.41
mmol/l
0.85
184
1335
201
1455
1.42
4.99
1.9
1.6
—
—
—
0
0
926
8205
1.21
4.81
10.4
6.2
0.66
0.65
%
0.19
881
7626
55
292
1.90
4.80
1.2
1.3
—
—
—
0
0
939
8334
1.21
4.79
10.2
6.2
25.53
25.59
%
0.05
898
7853
925
8205
1.21
4.73
10.3
6.2
2.82
2.79
%
0.15
877
7630
98
620
1.61
4.66
2.1
1.8
4.94
7.00
iu/ml
0.61
25
148
86
533
1.64
4.45
2.2
2.3
120.27
127.35
g/l
1.86
63
423
61
351
1.76
4.16
1.5
1.4
1820.27
4133.43
e6/l
0.46
40
250
218
1651
1.35
4.15
1.8
1.5
—
—
—
0
0
22
85
2.60
4.14
1.6
1.8
—
—
—
0
0
1522
16155
0.83
4.09
30.0
19.9
29.07
28.28
mg/l
0.40
1370
13792
32
148
2.18
4.09
2.3
1.3
—
—
—
0
0
32
148
2.18
4.09
2.3
1.3
7.54
6.90
g/l
0.43
25
109
32
148
2.18
4.09
2.3
1.3
0.50
0.43
g/l
0.46
24
109
32
148
2.18
4.09
2.3
1.3
2.61
2.82
g/l
0.28
23
110
141
999
1.44
3.99
2.1
1.9
2.52
2.17
ug/l
0.11
123
864
21
81
2.61
3.97
2.9
2.7
1158.14
1369.19
u/ml
0.19
21
81
53
297
1.80
3.97
1.6
1.5
—
—
—
0
0
51
283
1.82
3.94
7.4
6.3
13.55
12.56
mg/l
0.69
44
264
1075
9803
1.18
3.76
9.0
6.4
10.61
12.54
umol/l
8.70
1030
9308
25
109
2.31
3.69
1.8
2.6
37.70
38.72
%
—
10
61
1084
9903
1.18
3.68
13.6
9.2
4.44
4.35
e9/l
0.51
957
8510
60
358
1.69
3.65
3.4
3.9
1.12
1.81
%
1.16
53
313
598
5195
1.20
3.63
8.5
6.5
—
—
—
0
0
403
3365
1.24
3.63
3.0
2.6
2.21
2.24
g/l
0.44
377
3077
378
3144
1.24
3.52
3.1
2.6
21.35
21.69
%
0.18
359
2902
24
105
2.30
3.52
6.2
2.0
—
—
—
0
0
262
2088
1.29
3.50
3.4
3.2
6.32
5.08
e9/l
0.33
212
1762
342
2828
1.25
3.36
6.6
5.4
1.07
1.03
mmol/l
1.45
313
2591
1184
12735
0.86
3.36
36.7
25.9
330.12
331.18
g/l
3.36
1172
12608
240
1902
1.29
3.36
2.2
2.1
0.19
0.20
g/l
0.50
226
1753
181
1382
1.34
3.31
1.6
1.5
—
—
—
0
0
45
256
1.77
3.26
1.2
1.3
157.35
164.23
au/ml
0.17
17
72
52
313
1.68
3.11
1.6
1.4
29583.59
70297.65
e6/l
0.91
29
183
270
2198
1.26
3.05
3.3
3.9
52.08
20.05
ug/l
0.52
233
1844
33
175
1.90
3.00
4.9
1.7
—
—
—
0
0
421
3600
1.21
2.99
3.1
2.6
11.47
11.96
umol/l
0.77
401
3318
159
1211
1.34
2.98
9.6
9.7
15.72
15.70
%
0.02
152
1169
1202
12832
0.87
2.85
34.3
24.3
14.18
13.93
%
6.61
1193
12615
241
1954
1.26
2.83
9.7
6.6
1.36
1.40
mmol/l
0.29
235
1910
199
1577
1.29
2.82
6.0
4.1
0.66
0.73
%
0.16
87
526
622
5531
1.17
2.80
2.7
2.4
2.88
2.97
mg/l
0.47
537
4713
621
5522
1.17
2.79
4.0
3.1
33.64
35.96
u/l
0.55
585
5195
103
1411
0.72
2.78
2.0
2.3
11.81
12.39
nmol/l
0.28
87
1238
5
6
8.35
2.75
2.8
1.2
—
—
—
0
0
11
34
3.25
2.72
5.5
4.3
—
—
—
0
0
67
446
1.52
2.69
2.1
1.5
0.23
0.23
g/l
0.01
67
426
1140
12172
0.88
2.60
4.4
4.1
15.16
15.07
pmol/l
0.55
1027
10880
554
6217
0.86
2.58
3.3
3.4
67.54
47.93
mg/l
0.98
368
4080
572
6401
0.86
2.56
3.9
4.1
13.24
9.09
mg/mmol
0.80
358
4067
28
150
1.88
2.51
8.1
2.6
—
—
—
0
0
595
6617
0.86
2.43
4.7
4.1
—
0.72
—
0
25
230
1891
1.24
2.42
11.3
7.6
—
—
—
0
0
38
227
1.69
2.40
4.5
1.7
—
—
—
0
0
176
1406
1.27
2.37
4.3
3.8
7.41
7.42
ph
0.09
158
1181
72
501
1.45
2.36
3.2
3.1
88.26
88.57
%
0.15
72
487
8
22
3.65
2.36
9.9
14.5
5.41
5.20
mmol/l
—
8
22
24
125
1.93
2.35
1.3
1.1
250.00
146.00
titre
—
6
20
564
6283
0.87
2.35
2.0
1.9
1.29
1.31
mmol/l
0.31
485
5162
38
229
1.67
2.33
4.5
1.6
—
—
—
0
0
274
2304
1.21
2.33
4.9
3.4
5.84
5.83
kpa
0.03
266
2231
70
487
1.45
2.31
4.2
4.1
—
—
—
0
0
36
215
1.68
2.29
4.6
1.7
—
—
—
0
0
239
1987
1.23
2.27
7.4
6.4
11.53
11.39
mmol/l
0.10
229
1891
46
294
1.58
2.25
1.7
1.4
—
—
—
0
0
454
4003
1.17
2.25
5.3
4.3
433.42
319.45
ng/l
0.41
387
3457
205
1679
1.24
2.25
6.1
4.2
0.79
0.91
%
0.33
92
574
37
226
1.65
2.18
4.6
1.7
—
—
—
0
0
419
3681
1.17
2.17
2.1
1.7
1.32
1.53
mg/l
0.73
330
2895
64
444
1.45
2.16
1.3
1.2
—
—
—
0
0
265
2242
1.21
2.13
5.1
3.4
2.00
1.87
mmol/l
0.21
224
1898
385
4380
0.86
2.11
1.3
1.3
—
—
—
0
0
227
1898
1.22
2.06
4.1
3.2
226.89
272.65
ng/l
1.11
209
1754
177
1444
1.24
2.03
4.4
3.8
5.20
5.17
kpa
0.16
171
1369
8
26
3.08
2.01
1.1
1.0
—
—
—
0
0
73
528
1.39
1.99
1.6
1.7
0.33
0.32
mg/l
0.12
38
241
232
1954
1.21
1.97
2.5
2.7
66.20
65.89
g/l
0.23
208
1774
251
2131
1.20
1.96
2.7
2.5
67.12
67.72
e9/l
0.11
187
1601
337
2937
1.17
1.94
1.7
1.5
2.89
2.71
g/l
0.55
211
1731
37
234
1.59
1.93
4.0
3.7
57.03
58.18
%
0.11
32
204
42
274
1.54
1.92
7.0
7.9
7.31
7.50
mmol/l
0.15
36
232
15
71
2.12
1.92
1.4
1.2
—
—
—
0
0
24
135
1.79
1.91
3.7
2.7
27.29
28.75
mg/l
0.05
14
102
17
85
2.01
1.90
1.0
1.0
—
—
—
0
0
357
3134
1.16
1.88
2.4
2.0
29.93
29.89
s
0.05
352
3044
13
265
0.49
1.87
1.4
1.8
—
—
—
0
0
19
100
1.91
1.85
1.0
1.0
—
—
—
0
0
13
59
2.21
1.84
1.5
1.4
—
—
—
0
0
13
59
2.21
1.84
1.4
1.4
1.27
1.29
mm
—
8
41
136
1092
1.26
1.82
3.8
3.3
24.58
25.10
mmol/l
0.88
131
1056
77
572
1.36
1.81
3.2
3.2
7.60
7.76
kpa
0.46
77
559
28
169
1.66
1.77
1.6
1.2
—
—
—
0
0
190
1588
1.21
1.76
6.3
4.2
0.08
0.12
%
0.59
77
486
29
177
1.65
1.76
1.1
1.3
—
—
—
0
0
101
786
1.30
1.74
3.4
3.2
24.97
24.91
mmol/l
0.05
101
774
46
314
1.47
1.74
1.4
1.3
—
—
—
0
0
35
225
1.56
1.73
3.9
1.5
—
—
—
0
0
22
125
1.77
1.72
1.0
1.2
—
—
—
0
0
268
2319
1.18
1.70
4.9
3.4
7.37
7.38
ph
0.52
171
1390
62
450
1.39
1.69
1.2
1.2
—
—
—
0
0
183
1531
1.21
1.69
1.5
1.4
—
—
—
0
0
114
1424
0.79
1.69
5.2
4.3
—
—
—
0
0
33
211
1.57
1.68
4.8
4.4
—
—
—
0
0
582
6342
0.89
1.66
3.4
3.4
6.91
7.25
mmol/l
1.22
487
5270
23
134
1.72
1.66
1.2
1.2
—
—
—
0
0
30
188
1.60
1.66
1.4
1.2
2.24
6.92
u/ml
1.16
17
84
13
62
2.10
1.65
1.6
1.5
—
—
—
0
0
302
2647
1.16
1.64
1.4
1.3
61.56
36.69
iu/ml
0.75
91
853
57
411
1.40
1.63
1.5
1.3
59.46
60.55
mmol/l
0.08
48
324
224
1920
1.18
1.60
4.0
2.9
4.43
4.40
kpa
0.08
215
1855
37
246
1.51
1.60
1.1
1.1
—
—
—
0
0
107
850
1.27
1.59
1.9
2.2
0.00
1.09
estimate
0.50
32
230
8
32
2.51
1.59
1.0
1.2
—
—
—
0
0
50
354
1.42
1.59
1.2
1.2
—
—
—
0
0
19
106
1.80
1.58
1.5
1.1
—
—
—
0
0
81
621
1.32
1.58
3.2
1.9
20.15
21.05
s
1.19
74
570
59
431
1.38
1.57
1.7
2.7
28.38
33.82
umol/l
0.81
52
378
22
130
1.70
1.53
4.9
2.3
14.92
16.05
%
1.10
22
130
82
634
1.30
1.52
5.1
6.5
1.49
1.41
mmol/l
0.14
72
562
393
3530
1.14
1.52
6.7
4.7
—
—
—
0
0
7
27
2.60
1.51
1.6
1.4
72.29
53.78
umol/l
—
7
27
11
51
2.16
1.50
3.5
2.5
17.79
178.06
ug/l
0.48
11
43
32
210
1.53
1.48
1.1
1.1
—
—
—
0
0
59
436
1.36
1.48
4.6
7.7
103.64
105.43
mmol/l
1.74
53
393
59
436
1.36
1.48
4.6
7.7
11.66
11.46
mmol/l
0.12
53
393
71
540
1.32
1.48
1.2
1.2
1.23
0.91
u/ml
0.18
12
37
786
7361
1.10
1.44
4.2
3.8
6.38
6.26
ph
1.82
417
4072
5
16
3.13
1.44
1.0
1.0
—
—
—
0
0
14
73
1.92
1.43
2.1
4.1
63.00
54.03
%
0.80
14
67
15
81
1.86
1.40
1.2
1.3
7.71
104.66
ug/l
—
8
35
186
1591
1.18
1.39
7.1
4.4
0.03
0.15
%
1.86
66
447
36
247
1.46
1.38
1.1
1.0
—
—
—
0
0
926
8758
1.09
1.36
5.8
5.1
33.99
34.51
g/l
1.84
850
8126
220
1914
1.16
1.35
2.7
2.6
5.08
6.73
ug/l
1.64
180
1644
41
290
1.42
1.35
1.5
1.3
23.87
25.85
iu/l
0.15
33
242
0
38
0.00
1.34
0.0
1.1
—
0.71
—
0
21
8
34
2.36
1.29
1.0
1.0
—
—
—
0
0
381
3455
1.12
1.27
3.8
3.2
1.42
1.26
e6/l
0.26
229
1922
36
252
1.44
1.26
1.3
1.3
101.21
209.87
miu/ml
1.92
15
94
48
641
0.74
1.24
1.6
1.8
3.02
3.44
mmol/l
1.67
29
465
11
56
1.97
1.22
1.9
1.7
25.64
32.59
%
0.60
11
56
19
116
1.64
1.21
1.5
1.1
—
—
—
0
0
134
1130
1.20
1.21
1.8
1.7
1.49
1.55
g/l
0.30
116
966
6
26
2.31
1.18
1.3
1.2
—
—
—
0
0
6
26
2.31
1.18
3.0
1.0
—
—
—
0
0
639
5977
1.09
1.18
5.5
4.2
7.40
7.40
ph
0.72
497
4350
308
2774
1.13
1.17
2.7
2.4
1.84
1.80
%
0.37
268
2445
10
50
2.00
1.16
1.5
1.7
—
—
—
0
0
201
1761
1.15
1.15
2.8
2.4
37.23
36.11
u/l
0.09
169
1464
13
72
1.81
1.15
1.5
1.2
0.50
0.47
ratio
—
7
42
97
797
1.23
1.15
2.5
2.2
334.66
480.41
ug/l
0.79
91
751
16
95
1.69
1.13
1.1
1.1
—
3.40
—
0
5
110
917
1.21
1.13
4.6
5.5
0.89
0.87
%
0.22
103
868
98
809
1.22
1.11
1.3
1.2
—
—
—
0
0
625
5855
1.09
1.11
2.9
2.6
58.51
74.83
u/l
0.62
585
5388
277
2488
1.13
1.11
1.3
1.3
15.35
13.49
u/ml
0.18
104
887
1147
11922
0.93
1.10
6.6
5.3
6362.11
2018.24
e6/l
0.50
27
219
7
31
2.26
1.10
1.0
1.1
—
—
—
0
0
25
168
1.49
1.09
1.4
1.2
—
—
—
0
0
195
1717
1.15
1.06
2.2
2.1
0.00
0.01
estimate
0.50
37
318
263
2364
1.13
1.05
1.3
1.3
—
—
—
0
0
194
2188
0.88
1.00
5.0
5.1
32.33
33.21
%
0.43
116
1381
835
8760
0.93
1.00
2.4
2.3
89.45
93.05
pmol/l
1.44
470
4742
20
131
1.53
0.99
2.5
2.2
—
—
—
0
0
237
2127
1.13
0.98
2.6
2.7
5.83
9.63
umol/l
7.18
202
1903
1031
9898
1.07
0.98
9.3
7.3
1.21
1.21
mmol/l
0.13
893
8450
34
249
1.37
0.97
2.2
2.2
0.87
1.12
g/24h
0.36
22
143
117
1002
1.18
0.93
4.5
5.2
1.71
1.59
%
0.60
110
948
498
4660
1.09
0.92
5.7
4.2
86.64
83.46
%
2.19
487
4562
929
8904
1.07
0.91
8.6
6.6
1.20
1.21
mmol/l
0.50
846
8133
116
998
1.17
0.89
4.5
3.8
—
—
—
0
0
46
359
1.29
0.88
1.5
1.3
26.94
52.73
e6/l
0.43
33
270
8
42
1.91
0.88
2.4
1.4
—
—
—
0
0
27
194
1.40
0.88
1.2
1.5
25.65
31.70
ng/l
0.39
27
194
18
119
1.52
0.88
1.6
1.5
1094.36
1049.72
mu/l
0.07
13
96
448
4791
0.92
0.87
4.7
3.9
0.01
0.05
estimate
1.00
146
1551
29
212
1.37
0.86
1.2
1.2
—
—
—
0
0
32
238
1.35
0.86
1.2
1.3
—
—
—
0
0
22
153
1.44
0.85
1.4
1.4
7.44
7.40
ph
0.30
13
112
56
451
1.25
0.85
5.3
5.1
3.36
2.69
mmol/l
0.81
41
311
117
1012
1.16
0.85
2.5
2.5
27.97
17.75
au/ml
—
7
80
39
501
0.77
0.83
1.1
1.2
—
—
—
0
0
34
257
1.33
0.83
1.3
1.2
293.92
273.93
u/ml
0.11
24
135
46
363
1.27
0.83
1.6
1.4
25.81
591.98
e6/l
1.13
36
287
39
500
0.78
0.82
1.1
1.1
—
—
—
0
0
8
46
1.74
0.82
1.1
1.2
—
—
—
0
0
136
1195
1.15
0.81
4.3
2.5
1.26
1.16
%
0.74
136
1187
727
6936
1.07
0.80
4.0
3.4
2150.40
1930.46
ng/l
0.55
645
6029
95
813
1.18
0.80
1.3
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
0.53
—
0
9
105
907
1.17
0.79
1.3
1.3
75.40
58.65
au/ml
—
5
70
8
48
1.67
0.78
1.9
1.4
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
6.58
—
0
14
88
750
1.18
0.78
4.8
4.0
24.77
24.89
mmol/l
0.11
79
674
794
8277
0.94
0.77
3.6
2.9
—
—
estimate
—
0
0
174
1561
1.12
0.76
2.1
2.2
388.39
383.05
nmol/l
0.13
156
1422
6
34
1.77
0.76
23.2
7.3
7.20
5.15
kpa
—
6
34
11
67
1.64
0.75
1.0
1.1
—
—
—
0
0
56
679
0.82
0.75
1.4
1.4
—
—
—
0
0
34
262
1.30
0.74
1.4
2.4
35.88
170.66
u/ml
0.42
34
257
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
127
1437
0.88
0.74
3.8
3.0
6.09
6.04
ph
0.26
101
1042
8
132
0.60
0.73
3.3
2.5
—
—
—
0
0
6
107
0.56
0.72
1.7
1.4
0.65
1.12
nmol/l
—
6
74
54
443
1.22
0.72
1.2
1.2
50.00
93.25
titre
—
7
40
22
159
1.39
0.72
1.4
1.2
—
—
—
0
0
128
1442
0.88
0.70
1.5
1.5
—
—
—
0
0
27
203
1.33
0.70
1.3
1.3
—
—
—
0
0
133
1181
1.13
0.70
4.3
2.5
0.61
0.62
%
0.14
133
1174
55
454
1.22
0.70
3.1
2.7
15.13
16.00
%
1.33
55
445
77
657
1.18
0.69
1.9
1.5
—
—
—
0
0
5
28
1.79
0.66
4.2
2.8
0.82
0.66
ug/l
—
5
28
24
181
1.33
0.63
1.5
1.2
57.98
87.21
u/ml
—
6
8
436
4130
1.07
0.61
5.4
4.5
1.02
1.02
kg/l
0.05
298
2794
32
401
0.80
0.61
1.4
1.7
—
—
—
0
0
633
6067
1.06
0.61
2.6
2.2
232.94
245.03
u/l
0.14
595
5709
0
21
0.00
0.60
0.0
1.6
—
8.04
—
0
12
0
21
0.00
0.60
0.0
2.4
—
62.16
—
0
8
36
444
0.81
0.60
1.2
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
1.84
—
0
22
39
476
0.82
0.59
2.1
2.3
109.85
101.30
ug/min
0.05
22
282
345
3246
1.07
0.59
4.1
3.3
2.22
1.90
e6/l
0.37
186
1700
487
4636
1.06
0.59
3.5
2.8
5.79
4.84
e6/l
0.75
451
4234
63
539
1.17
0.58
1.5
1.5
266.14
267.25
ug/g
0.01
39
330
25
320
0.78
0.57
1.5
1.8
186.24
210.41
pmol/l
0.80
25
301
15
107
1.40
0.55
1.0
1.0
7.04
2.06
u/ml
—
7
52
1285
12576
1.05
0.54
6.9
4.5
17.14
14.50
mm/h
5.51
1200
11600
89
787
1.14
0.54
2.7
3.2
4689.45
5478.51
u/ml
0.05
78
683
22
169
1.30
0.53
1.4
1.2
—
—
—
0
0
6
39
1.54
0.53
23.2
7.2
5.78
6.08
kpa
—
6
34
509
4874
1.06
0.51
3.5
3.0
355.31
362.27
umol/l
0.65
437
4189
20
259
0.77
0.51
1.1
1.2
1.51
1.53
g/l
0.07
20
259
84
744
1.13
0.51
3.4
3.4
2.45
3.37
ratio
0.46
51
448
483
4624
1.06
0.49
3.7
3.4
0.08
0.07
0.03
13
172
47
399
1.18
0.49
2.2
1.5
—
—
—
0
0
14
190
0.74
0.49
1.5
1.3
668898.75
98306.58
e6/l
—
8
132
60
521
1.16
0.48
1.6
1.6
14.25
23.06
u/ml
0.76
13
95
117
1062
1.11
0.48
1.3
1.3
—
—
—
0
0
80
710
1.13
0.48
3.8
3.0
334.27
388.97
mg/l
0.19
41
296
7
47
1.49
0.47
1.4
2.9
3.43
727.02
ug/l
—
7
47
28
343
0.81
0.47
1.2
1.3
—
—
—
0
0
199
1855
1.08
0.46
1.3
1.3
—
—
—
0
0
7
49
1.43
0.46
2.3
1.9
—
—
—
0
0
5
83
0.60
0.45
1.6
3.0
—
—
—
0
0
172
1596
1.08
0.45
4.0
3.6
94.51
96.84
ng/l
0.12
147
1343
21
165
1.28
0.45
1.2
1.1
1.89
1.82
u/ml
0.02
12
86
183
1707
1.08
0.43
2.4
2.3
220.92
150.04
ug/g
1.10
145
1344
46
532
0.86
0.42
17.8
12.8
—
—
—
0
0
8
56
1.43
0.42
2.5
1.6
—
—
—
0
0
16
122
1.31
0.42
2.0
1.9
102.89
122.09
ng/l
0.52
16
122
0
16
0.00
0.41
0.0
1.1
—
0.18
—
0
9
792
7710
1.04
0.41
5.0
4.6
39.78
74.10
ng/l
2.13
618
6089
0
17
0.00
0.40
0.0
8.1
—
0.39
—
0
17
5
34
1.47
0.40
1.0
1.3
33.00
27.50
s
—
5
34
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
56.22
—
0
18
33
389
0.85
0.39
1.0
1.1
—
—
—
0
0
32
271
1.18
0.37
1.4
1.8
3.73
4.64
mmol/24h
0.97
27
233
16
125
1.28
0.37
1.0
1.1
—
—
—
0
0
21
171
1.23
0.35
1.4
1.3
—
—
—
0
0
89
814
1.10
0.35
3.7
3.6
65.85
82.77
mg/l
0.17
74
696
89
814
1.10
0.35
3.7
3.6
56.42
58.39
mg/l
0.05
74
694
72
791
0.91
0.32
1.2
1.3
—
—
—
0
0
673
6901
0.97
0.32
5.1
4.4
0.01
0.05
estimate
1.01
145
1665
19
230
0.82
0.31
2.5
2.2
—
—
—
0
0
765
7480
1.03
0.31
17.9
12.5
0.00
0.00
e9/l
0.01
616
6043
48
428
1.12
0.30
1.5
1.2
4.66
2.71
u/ml
—
7
37
91
842
1.08
0.29
2.2
2.5
10.51
10.50
g/l
0.01
78
739
76
827
0.92
0.29
1.2
1.2
109.11
124.15
u/ml
0.13
27
296
49
440
1.12
0.28
3.3
3.3
2286.72
950.70
u/ml
0.40
43
409
679
6642
1.03
0.27
3.5
3.4
2.34
2.35
mmol/l
0.99
603
5933
1087
11031
0.97
0.27
7.1
5.3
6.85
6.88
mmol/l
0.19
1044
10545
12
150
0.80
0.27
1.8
2.3
396.50
630.90
ml
—
6
91
22
187
1.18
0.26
1.1
1.1
—
—
—
0
0
786
7711
1.03
0.26
3.7
3.1
157.02
151.37
ug/l
0.22
716
7038
5
75
0.67
0.25
1.6
3.1
—
—
—
0
0
39
349
1.12
0.25
2.4
1.9
1.54
1.71
mmol/l
0.75
39
338
108
1147
0.94
0.24
1.2
1.2
—
—
—
0
0
81
868
0.93
0.23
2.0
2.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.0
—
0.28
—
0
8
926
9123
1.02
0.23
4.9
4.3
0.00
0.00
estimate
0.50
177
2022
26
228
1.14
0.22
1.1
1.1
192.45
75.95
iu/ml
—
6
35
11
88
1.25
0.22
1.2
1.0
—
—
—
0
0
419
4085
1.03
0.22
3.5
3.1
524.74
539.38
mosm/kgh2o
0.87
375
3586
0
10
0.00
0.21
0.0
5.0
—
—
—
0
0
8
101
0.79
0.21
1.0
1.2
130.63
135.40
nmol/l
—
8
101
29
258
1.13
0.21
1.1
1.1
—
—
—
0
0
43
392
1.10
0.21
1.2
1.2
40.08
38.53
u/l
0.04
36
341
1366
13530
1.02
0.21
12.0
8.3
80.10
82.45
u/l
0.97
1298
12723
5
43
1.16
0.21
1.2
1.5
—
—
—
0
0
64
595
1.08
0.21
3.3
3.4
0.79
0.84
nmol/l
0.64
55
491
0
13
0.00
0.21
0.0
1.4
—
1.46
—
0
6
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
937
9246
1.02
0.20
5.0
4.3
14.84
3.30
estimate
0.55
190
2078
942
9296
1.02
0.20
5.0
4.3
0.02
0.17
estimate
0.45
182
1952
791
7791
1.02
0.20
2.6
2.4
79.33
78.93
nmol/l
0.14
698
6834
6
50
1.20
0.19
1.2
1.1
—
—
—
0
0
6
50
1.20
0.19
1.2
1.1
—
—
—
0
0
6
50
1.20
0.19
1.2
1.1
—
—
—
0
0
6
51
1.18
0.19
2.5
1.5
1.72
1.76
umol/l
—
6
42
102
1074
0.95
0.19
4.1
3.8
1.02
1.02
ratio
0.96
92
982
19
165
1.15
0.19
1.7
1.4
—
—
—
0
0
569
5588
1.02
0.18
4.4
3.5
0.53
0.50
e6/l
0.16
457
4254
997
10086
0.98
0.18
4.5
3.3
57.11
55.44
u/l
0.18
942
9264
15
128
1.17
0.18
2.9
3.0
—
—
—
0
0
197
1904
1.04
0.18
4.2
4.5
7.37
7.36
ph
0.42
142
1347
241
2339
1.03
0.18
1.4
1.4
—
—
—
0
0
7
61
1.15
0.17
1.1
1.3
—
0.07
g/l
—
0
7
34
310
1.10
0.17
1.5
1.2
32.04
61.16
u/ml
—
9
27
537
5281
1.02
0.16
5.1
4.4
0.00
0.00
estimate
0.78
163
1783
8
72
1.11
0.16
1.4
1.1
—
—
—
0
0
8
73
1.10
0.15
1.4
1.3
—
—
—
0
0
6
78
0.77
0.15
1.0
1.1
—
—
—
0
0
7
88
0.79
0.14
3.6
1.8
12.00
17.11
nmol/l
—
7
78
331
3242
1.02
0.14
1.3
1.3
1.95
1.49
u/ml
0.24
84
834
615
6066
1.02
0.14
3.4
2.6
—
—
—
0
0
16
141
1.14
0.14
1.0
1.3
—
—
—
0
0
17
151
1.13
0.13
8.4
2.1
7.54
8.17
mmol/l
0.47
17
151
20
180
1.11
0.13
1.2
1.2
—
—
nmol/l
—
0
0
9
106
0.85
0.13
1.1
1.5
—
—
—
0
0
57
541
1.05
0.12
1.6
1.5
—
—
—
0
0
961
9690
0.99
0.12
19.3
19.6
1.31
1.38
inr
3.45
841
8172
15
134
1.12
0.11
1.0
1.1
92.87
101.44
pmol/l
0.34
15
134
19
173
1.10
0.10
1.3
1.1
—
—
—
0
0
19
173
1.10
0.10
1.3
1.1
—
—
—
0
0
5
44
1.14
0.10
1.4
1.5
7.53
7.36
mmol/l
—
5
44
466
4605
1.01
0.09
3.3
2.5
—
—
—
0
0
5
48
1.04
0.09
2.0
1.9
0.00
0.06
estimate
—
5
48
623
6285
0.99
0.08
4.2
3.6
—
—
—
0
0
16
146
1.10
0.08
1.1
1.6
—
—
—
0
0
46
440
1.05
0.08
4.1
3.9
32.61
29.76
mg/l
0.17
31
324
7
67
1.04
0.08
1.1
1.1
1.07
1.08
ratio
—
7
54
6
72
0.83
0.07
2.2
1.4
32.17
28.92
umol/l
—
6
65
56
581
0.96
0.07
4.1
4.7
—
—
—
0
0
667
6620
1.01
0.07
2.4
2.3
—
—
—
0
0
8
75
1.07
0.07
1.0
1.1
—
10.74
—
0
16
7
81
0.86
0.07
1.6
1.7
40.26
39.43
g/l
—
7
81
599
5945
1.01
0.07
1.9
1.8
19.58
19.74
nmol/l
0.09
511
4997
28
265
1.06
0.07
1.3
1.5
126.75
316.71
pmol/l
1.77
28
260
15
138
1.09
0.06
1.1
1.0
960.70
655.37
ng/l
—
10
82
20
213
0.94
0.06
1.7
1.5
66.67
64.22
%
0.11
15
138
96
939
1.02
0.06
3.7
2.7
—
—
—
0
0
10
110
0.91
0.05
1.3
1.8
—
—
—
0
0
19
179
1.06
0.05
1.1
1.2
—
—
—
0
0
411
4139
0.99
0.04
3.5
3.0
2.46
2.46
mmol/l
0.05
363
3676
718
7148
1.01
0.04
5.5
4.3
117.85
122.77
e6/l
0.06
552
5279
30
289
1.04
0.04
1.6
1.3
12.80
9.53
u/l
0.54
20
229
21
220
0.95
0.03
2.6
2.5
—
—
—
0
0
55
562
0.98
0.03
4.0
3.7
2.60
1.62
index
0.52
32
306
431
4290
1.01
0.03
1.7
1.8
49706346.96
8580908.69
pmol/l
0.56
340
3473
36
370
0.97
0.03
1.5
1.8
2.29
20.90
iu/l
0.58
13
140
38
370
1.03
0.03
1.9
2.1
0.91
0.87
%
0.26
31
268
408
4099
0.99
0.02
1.9
1.8
1133.44
1163.12
nmol/l
0.30
309
3066
13
122
1.07
0.02
2.2
2.2
4.08
3.07
ug/l
0.41
13
114
175
1736
1.01
0.02
3.3
2.6
0.55
0.52
e6/l
0.05
166
1669
103
1040
0.99
0.02
2.4
2.5
—
—
—
0
0
14
133
1.05
0.01
1.2
1.1
0.46
1.95
u/ml
—
5
53
162
1612
1.01
0.01
4.4
3.9
1.22
1.22
mmol/l
0.30
143
1377
652
6529
1.00
0.01
4.7
3.7
62.32
93.18
e6/l
0.89
539
5126
13
124
1.05
0.00
1.2
1.0
0.64
1.33
u/ml
—
6
65
13
125
1.04
0.00
1.5
1.3
—
—
—
0
0
14
135
1.04
0.00
1.2
1.1
4.09
4.57
u/ml
—
5
66
11
106
1.04
0.00
2.6
1.6
—
—
—
0
0
19
186
1.02
0.00
1.1
1.2
0.18
0.19
nmol/l
0.71
12
146
22
224
0.98
0.00
1.3
1.3
21.34
63.06
mu/l
1.84
17
196
49
488
1.00
0.00
1.6
1.6
7718.09
16787.74
e6/l
1.84
32
353
20
203
0.99
0.00
4.0
3.6
18.36
10.97
index
1.08
14
111
20
197
1.02
0.00
1.6
2.1
—
—
—
0
0
20
203
0.99
0.00
2.3
2.0
3.45
1.65
u/field
0.46
11
113
7
75
0.93
0.00
2.6
1.4
6.86
9.30
ug/l
—
7
65
5
59
0.85
0.00
1.2
1.1
1101.60
1518.90
miu/ml
—
5
59
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
-0.00
1.3
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
0.41
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
2.80
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
402.00
—
0
5
6
67
0.90
-0.00
1.2
1.2
83.93
229.27
iu/ml
—
6
67
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
320.39
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.5
26.18
27.06
g/l
—
5
41
0
6
0.00
-0.00
0.0
1.2
—
190.67
—
0
6
6
62
0.97
-0.00
3.2
2.4
0.60
0.61
mmol/l
—
6
62
0
5
0.00
-0.00
0.0
1.0
—
0.05
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.2
1.3
139.17
167.12
mmol/24h
—
6
63
0
5
0.00
-0.00
0.0
1.0
—
33.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint TBC_RESP and mortality.

Females

Parameter HR [95% CI] p-value
TBC_RESP 2.077 [1.85, 2.33] < 0.001
Birth year 0.996 [0.99, 1.0] 0.314

During the follow-up period (1.1.1998 — 31.12.2019), 1483 out of 2958 females with TBC_RESP died.

Males

Parameter HR [95% CI] p-value
TBC_RESP 2.815 [2.49, 3.19] < 0.001
Birth year 0.987 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 2702 out of 4601 males with TBC_RESP died.

Mortality risk

Mortality risk for people of age

years, who have TBC_RESP.

N-year risk Females Males
1 0.237% 0.513%
5 1.239% 3.228%
10 3.108% 7.591%
15 5.846% 14.501%
20 10.563% 23.591%

Relationships between endpoints

Index endpoint: TBC_RESP – Respiratory tuberculosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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