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Respiratory tuberculosis, bacteriologically and histologically confirmed

TBC_RESP_HISTOBACT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A15
  • Hospital discharge: ICD-9 011.[A|B]|012.[A|B]
  • Cause of death: ICD-10 A15
  • Cause of death: ICD-9 011.[A|B]|012.[A|B]

2 out of 7 registries used, show all original rules.

867

4. Check minimum number of events

None

867

5. Include endpoints

None

867

6. Filter based on genotype QC (FinnGen only)

735

Control definitions (FinnGen only)

Control exclude
TBC_RESP

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
A15-A19
Name in latin
Tuberculosis respiratoria bacteriologice et histologice confirmata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 735 242 493
Unadjusted period prevalence (%) 0.18 0.09 0.23
Median age at first event (years) 62.62 56.14 65.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
779
Matched controls
7790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
307.7
304
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
240.4
218
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
66.9
161.3
89
15
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.7
130.9
272
578
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.2
126.6
230
426
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
+∞
78.5
74
*
A70
ICPC
Tuberculosis
778.0
73.4
71
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
69.9
66
*
A15.6
ICD-10 Finland
Tuberculous pleurisy, confirmed bacteriologically and histologically
+∞
58.0
55
*
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
531.1
51.0
50
*
A15.3
ICD-10 Finland
Tuberculosis of lung, confirmed by unspecified means
451.8
43.6
43
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.3
43.2
213
807
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
63.8
41.7
48
8
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
41.0
377
1993
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
396.0
38.4
38
*
A15.7
ICD-10 Finland
Primary respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
33.6
32
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.7
33.3
81
186
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.8
33.2
79
178
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.2
33.1
94
244
R03BB04
ATC
tiotropium bromide; inhalant
3.1
32.6
168
643
1240
FHL
Bronchoscopy
7.5
32.5
48
68
TGC00
NOMESCO Finland
Bronchial lavation
5.9
30.1
56
101
0112A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, BAKTERIOL.VARMA]
+∞
29.4
28
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.9
29.1
160
632
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.6
28.1
102
314
J01MA14
ATC
moxifloxacin; systemic
3.2
27.0
118
408
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
25.0
84
245
A15.8
ICD-10 Finland
Other respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
24.1
23
*
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
+∞
24.1
23
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
7.2
23.9
36
52
R04.2
ICD-10 Finland
Haemoptysis
4.2
23.1
64
162
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.1
21.8
47
97
J47
ICD-10 Finland
Bronchiectasis
5.9
20.9
38
67
H02AB06
ATC
prednisolone; systemic
2.0
20.8
410
2748
A15.4
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, confirmed bacteriologically and histologically
+∞
19.9
19
*
J96.1
ICD-10 Finland
Chronic respiratory failure
4.3
18.4
48
116
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.2
18.4
197
1044
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.4
17.2
63
194
R03DA04
ATC
theophylline; systemic, rectal
2.7
16.6
98
396
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.4
16.5
62
194
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
16.5
405
2847
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
15.9
176
939
0119A
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, BAKTERIOLOG. VARMA]
+∞
15.7
15
*
0120B
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, HISTOLOGISESTI VARMENNETTU]
+∞
15.7
15
*
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
14.1
15.6
26
19
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.7
15.4
87
344
R03AC12
ATC
salmeterol; inhalant
3.0
15.0
70
249
R03AC02
ATC
salbutamol; inhalant
1.8
14.5
401
2882
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
14.4
77
296
R05
ICD-10 Finland
Cough
2.1
14.1
160
859
H02AB07
ATC
prednisone; oral
2.2
13.9
141
724
A16.1
ICD-10 Finland
Tuberculosis of lung, bacteriological and histological examination not done
+∞
13.6
13
*
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
+∞
13.6
13
*
XG410
NOMESCO Finland
Flow-volume spirometry
3.4
13.4
50
156
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
3.2
12.2
50
165
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
11.8
233
1495
R03BB01
ATC
ipratropium bromide; inhalant
2.5
11.7
74
309
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.3
11.7
92
425
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
5.0
11.3
24
49
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.5
11.2
38
111
SPAT1254
SPAT
Administration of medicine
2.0
11.1
137
753
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
11.1
158
913
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
4.7
11.0
25
54
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
10.9
357
2620
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
10.9
65
264
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
10.8
113
585
J01MA12
ATC
levofloxacin; systemic
1.8
10.5
172
1038
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
+∞
10.4
10
*
0110X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, EPÄILTY]
+∞
10.4
10
*
R99
ICPC
Respiratory disease other
4.4
10.4
26
61
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
9.8
148
870
M05BA04
ATC
alendronic acid; oral
2.2
9.4
78
368
A16.5
ICD-10 Finland
Tuberculous pleurisy, without mention of bacteriological or histological confirmation
+∞
9.4
9
*
0120A
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, BAKTERIOLOGISESTI VARMA]
+∞
9.4
9
*
N05BA02
ATC
chlordiazepoxide; systemic
3.6
9.3
30
85
J01FA06
ATC
roxithromycin; oral
1.6
9.2
298
2155
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.7
9.2
29
81
R50.9
ICD-10 Finland
Fever, unspecified
1.9
9.0
127
729
L04AX01
ATC
azathioprine; systemic
3.2
8.9
34
108
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.4
8.8
60
260
A31.9
ICD-10 Finland
Mycobacterial infection, unspecified
50.6
8.7
10
*
R03AC03
ATC
terbutaline; inhalant
2.0
8.7
98
521
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
8.6
156
967
R06.0
ICD-10 Finland
Dyspnoea
1.6
8.5
223
1527
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
8.5
128
750
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
91.0
8.4
9
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.6
8.4
49
197
0119X
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, EPÄILTY]
+∞
8.3
8
*
0118A
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, BAKTERIOLOG.VARMA]
+∞
8.3
8
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
8.3
8
*
A16.9
ICD-10 Finland
Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
+∞
8.3
8
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.2
8.3
22
54
Z20.1
ICD-10 Finland
Contact with and exposure to tuberculosis
11.9
8.1
14
12
J01AA02
ATC
doxycycline; systemic
1.6
8.0
560
4781
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
3.5
8.0
27
79
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.4
8.0
28
84
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.0
174
1132
F10.25
ICD-10 Finland
Alcohol dependence continuous use
4.3
8.0
20
47
R03BA01
ATC
beclometasone; inhalant
1.9
7.8
111
638
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.3
7.8
20
48
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
45.4
7.7
9
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
4.4
7.7
19
44
JN4AD
NOMESCO Finland
Body CT examination
1.9
7.6
93
508
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
25.3
7.6
10
*
L04AA13
ATC
[U] leflunomide
4.2
7.6
20
49
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.5
7.4
44
179
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
4.2
7.3
19
46
0120X
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, EPÄILTY]
+∞
7.3
7
*
A15.5
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, confirmed bacteriologically and histologically
+∞
7.3
7
*
A15
ICD-10 Finland
Respiratory tuberculosis, bacteriologically and histologically confirmed
+∞
7.3
7
*
J46
ICD-10 Finland
Status asthmaticus
3.5
7.3
25
74
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
4.3
7.0
18
43
J45.8
ICD-10 Finland
Mixed asthma
3.1
6.9
28
92
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
7.6
6.9
15
20
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
7.6
6.9
15
20
L88
ICPC
Rheumatoid/seropositive arthritis
2.9
6.9
32
114
L01BA01
ATC
methotrexate; systemic
3.0
6.9
30
103
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
4.2
6.8
18
44
N05CD07
ATC
temazepam; oral
1.7
6.8
125
774
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
5.7
6.8
18
32
R03AC13
ATC
formoterol; inhalant
2.4
6.7
47
206
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
4.2
6.6
17
41
WNF00
NOMESCO Finland
Infection source and contact determination
10.1
6.5
12
12
XW000
NOMESCO Finland
Bone marrow biopsy
2.5
6.5
39
159
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
6.3
6.5
16
26
A31.89
ICD-10 Finland
Other mycobacterial infections
70.4
6.4
7
*
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
7.5
6.4
14
19
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.6
6.4
37
149
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
+∞
6.3
6
*
A18.3
ICD-10 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands
+∞
6.3
6
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
6.3
6
*
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
6.3
6
*
0116A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA,BAKTER.VARMA]
+∞
6.3
6
*
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
26.9
6.2
8
*
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
5.4
6.2
17
32
R03BB02
ATC
oxitropium bromide; inhalant
3.8
6.1
18
48

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
64
99
6.95
40.17
8.0
2.6
—
—
—
0
0
198
750
3.20
39.84
1.9
1.8
—
—
—
0
0
70
203
3.69
20.93
1.4
1.3
—
—
—
0
0
311
1960
1.98
18.09
13.3
5.8
—
—
—
0
0
149
708
2.37
18.03
1.9
1.4
—
—
—
0
0
32
66
5.01
14.85
1.4
1.3
15.63
13.80
u/l
0.53
32
61
385
2726
1.82
14.71
12.9
6.1
9.38
9.11
%
0.79
366
2551
384
2726
1.81
14.47
12.8
6.0
2.82
2.83
%
0.01
366
2547
383
2721
1.80
14.36
12.9
6.1
0.65
0.64
%
0.11
366
2542
38
94
4.20
14.14
3.6
2.7
—
—
—
0
0
381
2715
1.79
14.03
12.4
6.0
58.45
58.74
%
0.15
365
2583
403
2924
1.78
13.91
12.4
5.9
0.65
0.61
e9/l
2.12
350
2489
404
2937
1.78
13.82
12.4
5.9
0.04
0.04
e9/l
0.10
354
2510
384
2770
1.76
13.33
12.7
6.1
25.78
25.73
%
0.03
368
2622
182
1043
1.97
13.29
4.7
3.3
0.80
0.82
mmol/l
1.65
175
983
410
3018
1.76
13.22
13.2
6.1
0.19
0.20
e9/l
0.40
362
2620
405
2975
1.75
13.11
12.5
6.0
2.15
1.85
e9/l
0.42
359
2619
33
82
4.16
12.22
1.6
1.5
—
—
—
0
0
33
82
4.16
12.22
1.6
1.5
—
—
—
0
0
33
82
4.16
12.22
1.6
1.5
—
—
—
0
0
33
82
4.16
12.22
1.6
1.5
—
—
—
0
0
162
941
1.91
11.19
2.5
2.0
—
—
—
0
0
284
2000
1.66
9.94
6.9
4.5
—
—
—
0
0
421
3272
1.62
9.90
16.4
9.3
4.42
4.29
e9/l
0.51
377
2847
17
14
12.38
9.88
2.5
2.9
—
—
—
0
0
124
690
1.95
9.65
1.4
1.4
454.19
440.00
titre
0.05
31
155
411
3211
1.59
9.19
12.0
6.6
9.98
12.26
umol/l
5.79
403
3058
40
144
2.87
8.45
1.4
2.1
13.15
13.19
mg/l
0.01
31
129
144
889
1.76
7.98
6.9
5.6
1.06
1.03
mmol/l
0.38
135
808
33
110
3.09
7.97
1.6
1.5
—
—
—
0
0
98
545
1.91
7.59
1.8
1.6
—
—
—
0
0
110
638
1.84
7.48
1.9
1.6
—
—
—
0
0
30
101
3.05
7.15
1.6
1.3
—
—
—
0
0
162
1067
1.65
7.02
3.4
2.6
2.16
2.23
g/l
0.96
151
980
113
683
1.77
6.69
2.8
4.5
21.12
26.22
ug/l
0.12
97
584
152
998
1.65
6.65
3.5
2.6
20.27
22.37
%
1.21
143
926
100
584
1.82
6.64
1.8
2.7
66.44
66.01
g/l
0.21
88
533
103
608
1.80
6.60
2.4
2.3
0.19
0.20
g/l
0.97
98
556
64
322
2.08
6.58
1.7
1.3
110.34
347.45
u/ml
1.80
58
298
169
1143
1.61
6.55
3.5
2.6
10.77
12.32
umol/l
2.43
159
1055
28
99
2.90
6.16
1.3
1.4
—
—
—
0
0
17
33
5.24
6.04
1.4
1.7
802.00
467.50
e6/l
0.68
12
28
29
106
2.80
6.01
1.5
1.3
2077.39
1421.14
e6/l
0.83
18
70
110
684
1.71
5.88
3.7
3.1
4.24
5.73
e9/l
0.99
83
584
234
1743
1.49
5.79
3.0
2.3
2.83
3.06
mg/l
0.75
205
1496
87
509
1.80
5.74
1.6
1.4
—
—
—
0
0
124
804
1.64
5.65
8.7
7.4
1.13
1.01
mmol/l
0.13
109
650
12
16
7.60
5.65
1.5
1.5
—
—
—
0
0
230
1716
1.48
5.62
9.8
6.3
—
—
—
0
0
25
88
2.90
5.56
1.2
1.7
0.95
0.86
g/l
0.11
18
76
14
24
5.92
5.55
1.9
2.1
1354.00
861.92
u/ml
0.46
14
24
351
2844
1.43
5.51
8.8
6.5
1.20
1.21
mmol/l
1.28
325
2591
17
47
3.68
5.50
1.4
1.2
—
—
—
0
0
65
353
1.92
5.42
1.7
1.5
—
—
—
0
0
344
2785
1.42
5.39
6.4
5.1
33.54
34.88
g/l
3.65
316
2594
124
815
1.62
5.35
8.7
7.3
5.06
5.10
kpa
0.18
118
777
124
816
1.62
5.32
8.7
7.3
11.50
11.59
kpa
0.04
119
782
75
431
1.82
5.26
4.3
4.9
—
—
—
0
0
24
86
2.85
5.18
1.6
1.2
—
—
—
0
0
30
121
2.54
5.18
1.5
1.3
58.75
57.71
mmol/l
0.04
24
100
112
731
1.62
4.96
2.2
1.7
—
—
—
0
0
25
96
2.66
4.77
1.6
1.2
32008.00
36364.54
e6/l
0.05
13
54
63
354
1.85
4.76
1.6
1.9
1.58
1.54
g/l
0.12
58
316
26
104
2.55
4.59
1.4
1.2
—
—
—
0
0
119
804
1.57
4.56
8.9
7.4
7.42
7.41
ph
0.25
73
471
17
54
3.20
4.51
1.5
1.2
—
—
—
0
0
106
705
1.58
4.34
4.5
3.5
5.79
5.81
kpa
0.08
101
686
12
24
5.06
4.33
1.2
1.2
—
—
—
0
0
89
573
1.62
4.17
11.2
8.3
—
—
—
0
0
100
663
1.58
4.15
2.9
2.6
66.23
67.82
e9/l
0.18
72
500
102
681
1.57
4.11
4.8
3.6
1.94
2.07
mmol/l
0.13
87
573
129
908
1.50
4.10
1.4
1.3
54.85
34.18
iu/ml
0.40
40
287
40
204
2.01
4.04
2.7
2.1
3.00
8.32
iu/ml
1.69
11
51
372
3154
1.34
4.00
9.7
7.2
1.20
1.21
mmol/l
0.84
329
2681
80
508
1.64
3.97
6.6
4.4
0.42
0.60
%
0.59
39
173
21
83
2.57
3.82
1.2
1.4
155.90
158.75
au/ml
—
10
22
69
426
1.68
3.81
10.6
8.5
24.23
24.40
mmol/l
0.17
69
414
122
864
1.49
3.76
2.9
2.5
1.81
1.81
%
0.03
108
777
15
50
3.04
3.70
1.5
1.2
—
—
—
0
0
238
1903
1.36
3.70
3.8
3.1
33.22
35.60
u/l
0.42
224
1798
495
4413
1.33
3.62
15.4
8.4
82.23
81.73
u/l
0.06
480
4147
103
714
1.51
3.52
4.6
3.6
7.38
7.38
ph
0.01
61
449
91
614
1.55
3.52
7.9
7.0
11.00
11.31
mmol/l
0.14
86
582
33
167
2.02
3.44
2.4
2.1
117.40
128.13
g/l
1.29
20
133
77
503
1.59
3.42
7.0
4.6
0.00
0.14
%
3.93
36
161
17
64
2.69
3.41
6.1
3.7
—
—
—
0
0
54
322
1.73
3.40
5.0
3.9
—
—
—
0
0
32
161
2.03
3.39
2.5
1.5
0.23
0.23
g/l
0.16
32
156
25
114
2.23
3.38
1.3
1.3
4.26
3.80
mmol/l
0.59
25
105
80
531
1.56
3.33
6.8
4.5
0.58
0.86
%
1.06
39
190
46
264
1.79
3.31
1.2
1.3
—
—
—
0
0
299
2512
1.31
3.23
21.4
12.4
0.00
0.00
e9/l
0.95
235
2045
17
66
2.61
3.23
1.1
1.1
—
—
—
0
0
53
320
1.70
3.21
2.5
2.6
35.60
14.99
au/ml
—
5
21
72
472
1.58
3.17
1.8
2.5
—
—
—
0
0
164
1267
1.37
3.12
2.2
1.7
1.24
1.47
mg/l
0.67
130
1012
15
57
2.66
2.98
1.9
1.9
—
—
—
0
0
235
1929
1.31
2.96
3.0
2.5
61.10
61.31
u/l
0.02
222
1797
140
1806
0.73
2.96
3.2
3.4
—
—
—
0
0
115
848
1.42
2.87
1.4
1.3
14.35
12.93
u/ml
0.07
36
321
234
1929
1.30
2.85
5.8
4.2
7.40
7.40
ph
0.28
180
1396
13
47
2.80
2.82
2.5
2.6
—
19.90
—
0
7
138
1053
1.38
2.82
1.5
1.4
2.73
2.62
g/l
0.24
91
628
261
2185
1.29
2.82
4.3
3.3
2618.53
1995.59
ng/l
1.03
235
1883
158
1233
1.35
2.81
2.0
1.8
1103.30
1148.11
nmol/l
0.26
118
926
163
1280
1.35
2.78
5.3
4.3
796.82
329.52
ng/l
0.76
138
1094
75
512
1.51
2.78
1.7
1.5
—
—
—
0
0
11
34
3.27
2.73
1.0
1.1
—
—
—
0
0
283
2405
1.28
2.70
4.0
3.8
6.36
6.23
ph
1.04
153
1375
10
29
3.48
2.70
1.0
1.0
—
—
—
0
0
101
739
1.42
2.64
1.4
1.2
—
—
—
0
0
38
222
1.75
2.62
1.8
1.6
0.33
0.34
mg/l
0.06
21
96
21
100
2.13
2.61
1.3
1.3
—
—
—
0
0
19
87
2.21
2.59
1.1
1.0
—
—
—
0
0
236
1970
1.28
2.57
3.8
2.6
—
—
—
0
0
79
555
1.47
2.56
2.2
2.0
402.91
385.78
nmol/l
0.40
70
515
12
44
2.75
2.55
1.3
1.3
—
—
—
0
0
15
62
2.45
2.55
3.1
2.3
—
—
—
0
0
538
5767
0.78
2.51
48.3
28.1
253.87
239.57
e9/l
3.97
528
5633
539
5771
0.79
2.44
48.3
28.1
7.48
6.97
e9/l
2.08
529
5614
539
5771
0.79
2.44
48.5
28.3
128.93
133.38
g/l
8.47
534
5679
539
5769
0.79
2.42
48.0
28.0
30.31
30.45
pg
0.86
534
5679
539
5769
0.79
2.42
49.1
28.6
38.99
39.77
%
2.85
533
5674
539
5769
0.79
2.42
48.1
28.1
4.31
4.42
e12/l
4.60
527
5612
539
5767
0.79
2.40
48.0
28.0
91.81
91.66
fl
0.27
534
5679
73
513
1.47
2.38
7.7
4.8
0.00
0.15
%
1.67
31
152
8
22
3.66
2.37
2.1
4.1
72.00
47.16
%
—
8
22
353
3117
1.24
2.34
18.7
18.1
1.28
1.35
inr
1.66
312
2631
255
2171
1.26
2.34
2.5
2.3
—
—
—
0
0
469
5086
0.80
2.28
5.4
5.1
1.48
1.42
mmol/l
2.34
430
4626
219
2578
0.79
2.27
4.9
5.7
6.24
4.93
ug/l
0.13
195
2282
26
142
1.86
2.25
1.3
1.2
—
—
—
0
0
23
121
1.93
2.23
2.4
1.7
—
—
—
0
0
230
1945
1.26
2.22
2.5
2.1
265.63
291.27
u/l
0.12
217
1836
11
41
2.71
2.21
1.5
1.1
—
—
—
0
0
11
41
2.71
2.21
1.4
1.4
—
—
—
0
0
28
158
1.80
2.20
5.7
4.1
—
—
—
0
0
78
567
1.42
2.14
5.2
4.3
7.37
7.35
ph
0.40
61
400
44
284
1.58
2.13
2.3
2.4
0.00
3.01
estimate
0.49
13
83
13
55
2.39
2.13
1.7
1.1
—
—
—
0
0
249
2134
1.25
2.12
3.4
3.5
2.34
2.35
mmol/l
0.79
213
1919
94
707
1.37
2.12
3.0
2.8
4.90
8.73
umol/l
4.81
82
636
11
43
2.58
2.08
1.6
1.5
—
—
—
0
0
35
215
1.66
2.07
1.4
3.5
2.56
2.98
ratio
0.18
22
125
20
103
1.97
2.07
2.6
1.9
—
—
—
0
0
487
5237
0.81
2.06
6.0
6.0
2.46
2.56
mmol/l
1.96
447
4766
45
296
1.55
2.02
2.0
1.7
—
—
—
0
0
177
1466
1.27
2.02
3.6
2.5
—
—
—
0
0
11
44
2.52
2.02
1.5
1.5
—
—
—
0
0
11
44
2.52
2.02
1.5
1.2
—
—
—
0
0
13
57
2.30
1.98
1.5
1.2
—
—
—
0
0
476
5122
0.82
1.98
5.3
5.2
4.38
4.44
mmol/l
0.67
436
4694
5
11
4.57
1.94
1.0
1.0
—
—
—
0
0
5
11
4.57
1.94
1.0
1.1
—
—
—
0
0
37
236
1.60
1.91
1.4
3.7
49.83
82.29
mg/l
0.66
31
200
37
236
1.60
1.91
1.4
3.7
33.38
51.22
mg/l
0.79
32
201
536
5691
0.81
1.90
41.7
24.9
86.23
85.43
umol/l
0.11
530
5594
14
65
2.17
1.89
1.3
1.2
—
—
—
0
0
21
114
1.87
1.88
1.4
1.3
23.56
18.12
e6/l
0.13
16
85
163
1350
1.26
1.86
4.4
4.1
—
0.23
—
0
22
293
2585
1.21
1.85
4.2
3.0
186.97
153.42
ug/l
0.90
273
2382
6
17
3.55
1.84
1.0
2.1
—
—
—
0
0
23
131
1.78
1.79
2.5
1.8
—
—
—
0
0
23
131
1.78
1.79
2.5
1.8
—
—
—
0
0
73
545
1.37
1.75
3.9
3.4
258.00
248.51
ng/l
0.06
64
500
188
1596
1.23
1.72
3.5
2.9
363.42
364.09
umol/l
0.02
163
1379
19
326
0.57
1.63
1.3
1.4
—
—
—
0
0
10
42
2.40
1.62
1.5
1.1
1.39
1.21
promille
—
10
33
8
32
2.52
1.60
5.6
3.8
114.63
133.72
nmol/l
—
8
32
19
106
1.81
1.60
1.5
1.3
73.36
257.65
miu/ml
—
9
42
285
2541
1.19
1.56
5.3
4.2
40.04
43.71
ng/l
0.31
215
1969
22
130
1.71
1.54
2.6
1.9
—
—
—
0
0
457
4884
0.84
1.53
4.5
4.4
1.20
1.28
mmol/l
1.45
413
4400
394
3617
1.18
1.53
7.5
5.1
6.63
6.81
mmol/l
1.00
377
3449
5
15
3.35
1.52
2.0
1.5
31.80
32.00
%
—
5
15
22
131
1.70
1.51
2.5
1.6
—
—
—
0
0
21
124
1.71
1.48
2.6
1.8
—
—
—
0
0
518
5470
0.84
1.47
26.7
16.7
—
—
—
0
0
382
3506
1.18
1.47
5.6
3.3
59.15
53.88
u/l
0.48
363
3264
5
16
3.14
1.44
1.0
3.2
3.40
5.31
ug/l
—
5
16
6
22
2.74
1.43
1.0
1.2
28.17
21.58
%
—
6
12
262
2334
1.18
1.43
5.7
4.3
86.98
134.68
e6/l
0.52
197
1741
484
5135
0.85
1.43
5.6
5.4
5.93
6.07
mmol/l
1.31
444
4626
126
1504
0.81
1.42
3.4
3.3
0.73
0.83
ug/l
0.84
83
1020
172
1988
0.83
1.41
3.7
3.5
76.89
56.16
mg/l
0.43
118
1329
13
67
1.96
1.39
1.2
1.2
2.63
7.29
u/ml
—
8
28
5
122
0.41
1.38
1.0
1.7
—
—
—
0
0
282
2537
1.17
1.36
2.7
2.4
78.29
77.54
nmol/l
0.14
253
2249
133
1121
1.22
1.31
4.2
3.3
1.19
1.10
e6/l
0.09
80
632
6
24
2.51
1.30
21.8
16.6
726.17
948.83
nmol/l
—
6
24
10
48
2.10
1.28
2.1
2.1
—
—
—
0
0
328
3001
1.16
1.26
4.6
4.2
0.00
0.00
estimate
-0.00
57
677
28
187
1.52
1.25
1.1
1.2
0.28
2.19
u/ml
—
5
13
25
163
1.55
1.24
4.0
2.5
86.75
88.32
%
0.55
25
157
25
163
1.55
1.24
1.2
1.2
—
—
—
0
0
9
45
2.01
1.23
3.2
2.6
—
—
—
0
0
35
246
1.44
1.23
1.9
2.5
10.87
10.95
g/l
0.04
25
215
180
2048
0.84
1.23
4.4
4.1
12.24
9.64
mg/mmol
0.35
116
1318
479
5059
0.86
1.22
6.6
6.9
40.05
40.11
mmol/mol
0.04
443
4666
11
56
1.98
1.22
1.3
1.3
—
—
—
0
0
125
1058
1.22
1.19
4.4
3.4
1.65
1.59
e6/l
0.05
70
567
16
94
1.72
1.18
1.1
1.1
—
—
—
0
0
534
5584
0.86
1.15
21.6
12.5
24.30
25.72
u/l
1.42
525
5390
27
183
1.49
1.14
4.2
8.2
1.72
1.49
mmol/l
0.13
22
162
332
3058
1.15
1.14
4.8
4.3
0.00
0.47
estimate
0.51
56
653
532
5562
0.86
1.13
38.3
23.0
4.00
4.01
mmol/l
0.25
524
5426
17
104
1.65
1.10
4.6
3.1
4.51
4.54
e9/l
0.02
17
104
5
21
2.39
1.09
1.0
1.0
—
—
—
0
0
292
2675
1.15
1.07
3.9
3.0
—
—
estimate
—
0
0
533
5561
0.87
1.05
37.9
22.7
138.86
139.61
mmol/l
6.97
526
5434
22
146
1.52
1.04
8.5
4.8
3.79
2.59
mmol/l
0.76
14
96
328
3034
1.14
1.03
4.8
4.3
0.00
2.34
estimate
0.50
61
695
138
1202
1.18
0.98
8.0
4.9
—
—
—
0
0
9
50
1.81
0.97
1.2
1.2
—
—
—
0
0
191
1710
1.15
0.96
4.7
3.5
—
0.00
estimate
—
0
13
11
62
1.79
0.94
4.5
3.3
7.45
6.09
nmol/l
0.13
11
62
30
218
1.39
0.92
3.8
3.2
389.62
276.62
mg/l
0.36
13
85
10
55
1.83
0.92
1.5
1.2
—
—
—
0
0
13
78
1.68
0.92
1.2
1.1
—
—
—
0
0
60
484
1.26
0.92
4.5
4.0
98.70
91.60
ng/l
0.21
50
421
6
28
2.15
0.91
1.5
1.3
—
—
—
0
0
468
4903
0.89
0.90
5.6
5.1
1.85
1.99
mu/l
1.88
423
4428
24
168
1.44
0.90
1.7
1.4
315.48
287.91
ug/g
0.22
16
97
39
298
1.32
0.89
1.2
1.2
129.28
131.95
u/ml
0.01
15
111
67
550
1.24
0.89
2.3
2.3
0.00
0.00
estimate
-0.00
12
103
8
43
1.87
0.87
1.5
1.3
—
—
—
0
0
6
30
2.01
0.87
1.0
1.1
—
9.10
—
0
8
151
1339
1.16
0.87
3.5
3.2
535.08
541.34
mosm/kgh2o
0.15
137
1172
8
44
1.83
0.86
1.0
1.0
—
—
—
0
0
16
104
1.55
0.85
1.3
1.2
355.11
260.94
u/ml
—
9
52
38
487
0.77
0.83
5.4
4.0
—
—
—
0
0
8
46
1.75
0.82
1.0
1.2
—
—
—
0
0
41
320
1.30
0.82
1.3
1.2
—
—
—
0
0
14
89
1.58
0.81
4.0
2.9
—
—
—
0
0
192
2110
0.88
0.81
2.1
2.0
1.22
1.32
mmol/l
1.11
169
1738
211
1925
1.13
0.81
2.1
1.8
19.60
20.20
nmol/l
0.24
182
1628
150
1339
1.15
0.79
1.7
1.8
483.94
5210678.04
pmol/l
0.50
125
1094
0
24
0.00
0.79
0.0
3.6
—
—
—
0
0
22
157
1.41
0.77
1.1
1.7
—
—
—
0
0
201
1835
1.13
0.76
4.7
3.6
0.66
0.49
e6/l
0.47
161
1408
0
28
0.00
0.76
0.0
3.5
—
—
—
0
0
382
4018
0.90
0.73
4.6
4.0
15.20
14.97
pmol/l
0.98
346
3602
5
25
2.01
0.72
1.6
1.8
38.00
54.46
ug/l
—
5
25
9
56
1.61
0.72
1.1
1.1
—
—
—
0
0
68
574
1.20
0.72
2.6
2.6
6.58
6.97
ug/l
0.08
52
499
9
57
1.59
0.71
1.1
1.2
—
—
—
0
0
9
58
1.56
0.70
1.9
1.7
9.20
10.41
%
—
9
58
10
61
1.65
0.68
1.1
1.3
29.37
28.49
ng/l
—
10
61
230
2130
1.11
0.68
4.9
3.7
36.79
117.36
e6/l
1.81
190
1683
149
1345
1.13
0.68
4.7
4.4
1.02
1.02
kg/l
0.41
102
929
21
283
0.73
0.67
1.7
1.8
2.75
3.50
mmol/l
3.14
13
214
5
28
1.79
0.66
1.8
2.0
41.38
40.25
g/l
—
5
28
188
2043
0.89
0.66
3.7
3.4
6.59
7.54
mmol/l
2.51
159
1703
67
571
1.19
0.65
3.5
2.5
34.36
35.05
u/l
0.06
61
470
7
44
1.60
0.65
1.0
1.9
—
—
—
0
0
7
44
1.60
0.65
1.0
1.3
76.14
95.86
pmol/l
—
7
44
167
1526
1.12
0.63
3.7
2.8
4.51
4.63
e6/l
0.06
154
1396
19
138
1.39
0.63
4.9
3.1
59.28
60.33
%
0.15
19
138
8
49
1.64
0.62
1.3
1.4
—
—
—
0
0
25
191
1.32
0.61
4.0
2.6
7.20
7.78
kpa
1.30
25
186
5
30
1.67
0.61
1.2
1.0
—
—
—
0
0
21
156
1.36
0.61
1.8
1.6
8150.00
14160.20
e6/l
0.75
16
114
9
140
0.64
0.61
1.1
1.1
—
—
—
0
0
26
202
1.30
0.58
4.0
2.8
1.50
1.71
mg/l
0.75
26
178
35
283
1.25
0.57
1.3
1.2
—
—
—
0
0
86
758
1.15
0.57
1.4
1.4
—
—
—
0
0
12
81
1.49
0.57
1.1
1.2
—
—
—
0
0
6
36
1.67
0.56
1.3
1.1
236.33
252.23
mg/l
—
6
30
201
2158
0.91
0.56
5.9
3.9
—
0.78
—
0
9
15
108
1.40
0.53
1.5
1.4
—
—
—
0
0
19
144
1.33
0.51
3.4
4.0
33.07
31.23
mg/l
—
10
106
67
586
1.16
0.51
2.4
2.3
275.29
141.74
ug/g
0.97
52
471
7
107
0.65
0.49
1.0
1.1
1.61
1.54
g/l
—
7
107
11
76
1.45
0.48
3.0
1.9
85.44
89.71
%
0.67
11
76
36
302
1.20
0.45
4.0
3.0
—
—
—
0
0
26
211
1.24
0.44
2.7
2.8
143.29
61.44
u/ml
0.41
26
203
41
478
0.85
0.43
3.5
3.1
6.23
6.07
ph
0.53
28
346
528
5405
0.93
0.42
36.1
19.0
28.85
27.35
mg/l
0.52
482
4579
402
3887
1.07
0.42
6.6
5.1
5189.75
2358.45
e6/l
0.23
12
75
17
217
0.78
0.42
1.1
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
7.59
—
0
16
0
17
0.00
0.40
0.0
5.9
—
49.71
—
0
12
5
34
1.47
0.40
2.2
1.5
9.40
1.20
%
—
5
28
43
495
0.86
0.40
1.7
1.6
—
—
—
0
0
14
181
0.77
0.38
1.3
1.9
48.00
42.61
nmol/l
0.38
14
173
8
115
0.69
0.37
1.1
1.2
0.79
0.88
g/l
—
8
115
5
77
0.65
0.36
1.2
1.4
—
0.54
—
0
5
6
42
1.43
0.35
1.3
1.9
79.67
104.63
ng/l
—
6
42
6
42
1.43
0.35
2.0
1.5
84.00
65.48
%
—
6
29
141
1322
1.08
0.34
3.5
3.2
2.46
2.46
mmol/l
0.12
122
1179
289
2785
1.06
0.32
2.7
2.3
87.12
93.77
pmol/l
1.86
178
1506
12
154
0.78
0.32
1.2
1.2
—
—
—
0
0
16
129
1.25
0.30
1.4
1.6
736.13
280.76
mu/l
0.76
16
120
13
161
0.80
0.27
1.5
1.7
—
—
—
0
0
12
149
0.80
0.26
1.0
1.1
—
—
—
0
0
140
1473
0.94
0.26
1.3
1.4
—
—
—
0
0
11
87
1.27
0.24
5.7
4.9
351.09
339.47
umol/l
0.14
11
77
21
181
1.16
0.22
4.3
3.6
2.93
1.76
index
0.25
13
104
19
163
1.17
0.21
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
5.9
—
7.02
—
0
11
0
12
0.00
0.21
0.0
1.1
—
0.82
—
0
5
5
43
1.16
0.21
1.0
1.0
211.20
280.46
ng/l
—
5
28
6
53
1.13
0.18
7.0
2.9
7.82
7.83
mmol/l
—
6
53
119
1141
1.05
0.17
1.4
1.3
3.87
1.42
u/ml
0.45
24
285
159
1645
0.96
0.17
4.4
3.7
0.00
0.07
estimate
0.86
49
522
5
66
0.76
0.17
1.2
1.4
—
—
nmol/l
—
0
0
67
633
1.06
0.16
1.3
1.3
—
—
—
0
0
25
276
0.90
0.15
1.8
2.0
—
—
—
0
0
12
140
0.85
0.15
1.2
1.9
171.17
224.96
pmol/l
1.08
12
131
41
381
1.08
0.15
1.2
1.2
—
—
—
0
0
33
355
0.93
0.13
1.1
1.4
—
—
—
0
0
190
1945
0.97
0.12
4.1
3.5
—
—
—
0
0
177
1728
1.03
0.12
5.1
4.3
0.00
0.01
estimate
0.78
54
599
13
114
1.14
0.12
4.2
3.4
11.48
9.82
pmol/l
0.16
13
114
234
2295
1.03
0.12
4.6
4.3
0.04
0.05
estimate
0.04
47
567
15
168
0.89
0.11
15.9
12.1
—
—
—
0
0
5
45
1.11
0.10
1.6
2.0
—
—
—
0
0
11
97
1.14
0.09
1.6
1.9
32.45
33.04
pg
0.20
11
97
17
185
0.92
0.08
3.4
4.9
—
—
—
0
0
5
65
0.77
0.08
1.0
2.2
—
—
—
0
0
7
67
1.05
0.08
1.7
1.0
—
—
—
0
0
7
67
1.05
0.08
1.7
1.0
—
—
—
0
0
14
153
0.91
0.07
1.5
2.5
130.50
99.21
ug/min
—
6
94
32
305
1.05
0.06
2.3
2.5
—
—
—
0
0
11
113
0.97
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
3.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
71.00
—
0
8
5
52
0.96
0.00
7.2
2.9
13.58
15.93
%
—
5
52
0
8
0.00
0.00
0.0
1.1
—
46.74
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.27
—
0
5
5
56
0.89
-0.00
1.4
2.5
1574.60
1045.58
mg
—
5
56
0
6
0.00
-0.00
0.0
1.3
—
1.90
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.43
—
0
6
0
9
0.00
-0.00
0.0
3.7
—
—
—
0
0
7
72
0.97
-0.00
1.6
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
0.59
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: TBC_RESP_HISTOBACT – Respiratory tuberculosis, bacteriologically and histologically confirmed

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).