Respiratory tuberculosis, confirmed, including avohilmo

AB1_RESP_TUBERCU_CONF_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A15
  • Hospital discharge: ICD-10 A15
  • Hospital discharge: ICD-9 01[1-2].A
  • Cause of death: ICD-10 A15
  • Cause of death: ICD-9 01[1-2].A

3 out of 7 registries used, show all original rules.

854

4. Check minimum number of events

None

854

5. Include endpoints

None

854

6. Filter based on genotype QC (FinnGen only)

721

Control definitions (FinnGen only)

Control exclude
AB1_TUBERCULOSIS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 721 236 485
Unadjusted period prevalence (%) 0.18 0.08 0.22
Median age at first event (years) 63.52 56.86 66.76

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
766
Matched controls
7660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
307.7
308
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
240.7
218
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
92.6
171.4
90
11
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.8
131.1
271
574
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.4
129.0
230
419
0110A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, BAKTER.VARMA]
+∞
78.5
74
*
A70
ICPC
Tuberculosis
791.5
74.5
72
*
A15.2
ICD-10 Finland
Tuberculosis of lung, confirmed histologically
+∞
72.0
68
*
A15.6
ICD-10 Finland
Tuberculous pleurisy, confirmed bacteriologically and histologically
+∞
58.1
55
*
A15.9
ICD-10 Finland
Respiratory tuberculosis unspecified, confirmed bacteriologically and histologically
+∞
55.9
53
*
A15.3
ICD-10 Finland
Tuberculosis of lung, confirmed by unspecified means
+∞
48.4
46
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
44.0
377
1944
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.3
43.9
210
783
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
63.9
41.7
48
8
A16.0
ICD-10 Finland
Tuberculosis of lung, bacteriologically and histologically negative
396.3
38.4
38
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
5.1
37.1
83
178
A15.7
ICD-10 Finland
Primary respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
34.6
33
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.1
32.4
161
604
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.2
32.2
92
240
R03BB04
ATC
tiotropium bromide; inhalant
3.1
32.1
166
637
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.8
31.6
76
173
TGC00
NOMESCO Finland
Bronchial lavation
5.8
29.4
55
100
0112A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung with cavitation[TUBERCULOSIS PULMONUM CAVERNOSA, BAKTERIOL.VARMA]
+∞
29.4
28
*
J01MA14
ATC
moxifloxacin; systemic
3.4
29.2
119
395
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.6
27.8
100
306
GD1AD
NOMESCO Finland
Thorax CT examination
3.8
26.1
85
243
1240
FHL
Bronchoscopy
6.5
24.7
41
66
R04.2
ICD-10 Finland
Haemoptysis
4.4
24.1
64
157
A16.2
ICD-10 Finland
Tuberculosis of lung, without mention of bacteriological or histological confirmation
+∞
24.1
23
*
A15.8
ICD-10 Finland
Other respiratory tuberculosis, confirmed bacteriologically and histologically
+∞
24.1
23
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
7.1
23.5
36
53
J47
ICD-10 Finland
Bronchiectasis
6.3
23.5
40
66
A15.4
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, confirmed bacteriologically and histologically
+∞
22.0
21
*
H02AB06
ATC
prednisolone; systemic
2.1
21.5
404
2678
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.0
21.3
47
99
J96.1
ICD-10 Finland
Chronic respiratory failure
4.3
18.4
48
116
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
18.4
406
2795
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.2
18.2
194
1026
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.6
18.0
63
188
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
17.2
178
928
R03DA04
ATC
theophylline; systemic, rectal
2.7
17.0
96
380
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.5
16.8
61
187
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
14.7
16.4
27
19
R03AC12
ATC
salmeterol; inhalant
3.2
16.4
70
237
0119A
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, BAKTERIOLOG. VARMA]
+∞
15.7
15
*
R05
ICD-10 Finland
Cough
2.2
15.5
162
845
R03AC02
ATC
salbutamol; inhalant
1.8
14.6
395
2829
H02AB07
ATC
prednisone; oral
2.2
14.5
139
699
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.7
14.4
84
337
XG410
NOMESCO Finland
Flow-volume spirometry
3.4
14.1
51
156
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.7
13.9
76
295
A16.1
ICD-10 Finland
Tuberculosis of lung, bacteriological and histological examination not done
+∞
13.6
13
*
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
+∞
13.6
13
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
5.6
13.1
25
46
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
12.7
116
571
R03BB01
ATC
ipratropium bromide; inhalant
2.6
12.5
75
305
J01MA12
ATC
levofloxacin; systemic
1.9
12.5
175
1010
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
12.3
232
1472
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
3.2
11.9
49
162
SPAT1254
SPAT
Administration of medicine
2.0
11.8
136
732
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
11.6
157
892
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
11.6
353
2559
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
11.5
11
*
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.3
11.3
90
418
R99
ICPC
Respiratory disease other
4.5
10.8
26
59
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.5
10.7
37
110
0310A
ICD-9 Finland
Diseases due to other mycobacteria, Pulmonary
+∞
10.4
10
*
J45.1
ICD-10 Finland
Nonallergic asthma
2.5
10.2
64
266
R50.9
ICD-10 Finland
Fever, unspecified
2.0
10.1
128
709
M05BA04
ATC
alendronic acid; oral
2.3
10.1
78
357
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
9.9
146
852
N05BA02
ATC
chlordiazepoxide; systemic
3.9
9.8
29
77
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.9
9.8
29
77
L04AX01
ATC
azathioprine; systemic
3.5
9.8
34
101
J01FA06
ATC
roxithromycin; oral
1.6
9.7
295
2111
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.7
225
1500
A31.9
ICD-10 Finland
Mycobacterial infection, unspecified
55.7
9.7
11
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
4.4
9.6
24
56
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
9.5
60
251
0110X
ICD-9 Finland
Pulmonary tuberculosis, Tuberculosis of lung, infiltrative[TUBERCULOSIS PULMONUM INFILTRATIVA, EPÄILTY]
+∞
9.4
9
*
0120A
ICD-9 Finland
Other respiratory tuberculosis, Tuberculous pleurisy[TUBERCULOSIS PLEURAE, BAKTERIOLOGISESTI VARMA]
+∞
9.4
9
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
9.3
128
730
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.5
9.1
22
50
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
9.1
156
952
R03AC03
ATC
terbutaline; inhalant
2.0
9.1
98
513
Z20.1
ICD-10 Finland
Contact with and exposure to tuberculosis
12.7
8.9
15
12
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.9
176
1120
F10.25
ICD-10 Finland
Alcohol dependence continuous use
4.6
8.6
20
44
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.6
8.4
28
81
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
91.0
8.4
9
*
0118A
ICD-9 Finland
Pulmonary tuberculosis, Other specified pulmonary tuberculosis[TUBERCULOSIS PULMONUM ALIA, BAKTERIOLOG.VARMA]
+∞
8.3
8
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
8.3
8
*
0119X
ICD-9 Finland
Pulmonary tuberculosis, unspecified[TUBERCULOSIS PULMONUM NUD, EPÄILTY]
+∞
8.3
8
*
A16.5
ICD-10 Finland
Tuberculous pleurisy, without mention of bacteriological or histological confirmation
+∞
8.3
8
*
A15.5
ICD-10 Finland
Tuberculosis of larynx, trachea and bronchus, confirmed bacteriologically and histologically
+∞
8.3
8
*
J46
ICD-10 Finland
Status asthmaticus
3.6
8.0
26
74
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
4.5
7.9
19
43
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
4.5
7.9
19
43
J01AA02
ATC
doxycycline; systemic
1.6
7.9
551
4704
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
3.6
7.9
26
75
R03BA01
ATC
beclometasone; inhalant
1.9
7.8
109
622
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
45.4
7.7
9
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.2
7.6
20
49
J45.8
ICD-10 Finland
Mixed asthma
3.3
7.5
28
88
JN4AD
NOMESCO Finland
Body CT examination
1.9
7.4
92
505
L04AA13
ATC
[U] leflunomide
4.2
7.3
19
46
A19.1
ICD-10 Finland
Acute miliary tuberculosis of multiple sites
+∞
7.3
7
*
A16.9
ICD-10 Finland
Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
+∞
7.3
7
*
A15
ICD-10 Finland
Respiratory tuberculosis, bacteriologically and histologically confirmed
+∞
7.3
7
*
A18.0
ICD-10 Finland
Tuberculosis of bones and joints
+∞
7.3
7
*
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
4.4
7.2
18
42
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
6.1
7.1
18
30
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.5
7.0
42
171
R03BB02
ATC
oxitropium bromide; inhalant
4.3
7.0
18
43
L88
ICPC
Rheumatoid/seropositive arthritis
2.9
7.0
31
108
N05CD07
ATC
temazepam; oral
1.8
7.0
122
746
A02BC02
ATC
pantoprazole; systemic
1.5
6.8
474
3972
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.7
6.8
35
132
XW000
NOMESCO Finland
Bone marrow biopsy
2.6
6.8
39
156
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.4
6.8
44
187
WNF00
NOMESCO Finland
Infection source and contact determination
10.1
6.5
12
12
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
6.3
6.5
16
26
A31.89
ICD-10 Finland
Other mycobacterial infections
70.4
6.4
7
*
R81
ICPC
Pneumonia
2.7
6.4
34
131
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
5.6
6.3
17
31
V03AA01, ,
ATC
3.9
6.3
18
47
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
6.3
6
*
0116A
ICD-9 Finland
Pulmonary tuberculosis, Tuberculous pneumonia [any form][TUBERCULOSIS PULMONUM CUM PNEUMONIA,BAKTER.VARMA]
+∞
6.3
6
*
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
6.3
6
*
A18.3
ICD-10 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands
+∞
6.3
6
*
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.1
6.2
25
82
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
26.9
6.2
8
*
R03AC13
ATC
formoterol; inhalant
2.3
6.2
45
201
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
6.2
129
826
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.5
6.1
36
146
L01BA01
ATC
methotrexate; systemic
2.9
6.1
28
100
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
6.0
178
1242

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
202
746
3.32
42.77
1.9
1.8
—
—
—
0
0
64
97
7.11
40.96
8.0
2.7
—
—
—
0
0
70
203
3.69
20.94
1.4
1.3
—
—
—
0
0
313
1921
2.06
20.23
13.4
5.9
—
—
—
0
0
148
696
2.40
18.38
1.9
1.4
—
—
—
0
0
387
2678
1.90
16.71
13.0
6.2
9.35
9.15
%
0.53
367
2510
386
2677
1.89
16.47
12.9
6.0
2.83
2.84
%
0.03
367
2503
385
2672
1.89
16.35
12.6
6.1
58.44
58.69
%
0.13
368
2545
385
2673
1.89
16.33
13.0
6.1
0.64
0.64
%
0.09
367
2501
407
2879
1.88
16.25
12.5
5.9
0.65
0.61
e9/l
2.03
352
2450
408
2892
1.88
16.15
12.6
5.9
0.04
0.04
e9/l
0.22
356
2470
33
65
5.26
16.12
1.5
1.3
15.55
13.77
u/l
0.53
33
60
39
90
4.51
15.85
4.8
2.8
—
—
—
0
0
387
2721
1.85
15.49
13.0
6.2
25.76
25.74
%
0.01
370
2579
409
2928
1.85
15.43
12.7
6.0
2.17
1.82
e9/l
0.52
361
2578
413
2970
1.85
15.31
13.4
6.1
0.19
0.20
e9/l
0.29
363
2577
34
77
4.57
14.14
1.6
1.5
—
—
—
0
0
34
77
4.57
14.14
1.6
1.5
—
—
—
0
0
34
77
4.57
14.14
1.6
1.5
—
—
—
0
0
34
77
4.57
14.14
1.6
1.5
—
—
—
0
0
182
1029
2.01
13.91
4.7
3.3
0.80
0.82
mmol/l
1.72
175
972
163
936
1.94
11.73
2.6
2.0
—
—
—
0
0
288
1971
1.74
11.67
6.9
4.5
—
—
—
0
0
423
3228
1.69
11.37
16.6
9.3
4.42
4.30
e9/l
0.47
377
2805
415
3151
1.69
11.37
12.0
6.6
10.11
12.30
umol/l
5.32
407
3008
41
138
3.08
9.71
1.4
2.1
13.20
13.27
mg/l
0.01
32
123
122
681
1.94
9.41
1.4
1.3
453.33
442.06
titre
0.04
30
155
17
16
10.84
9.32
2.5
2.8
—
—
—
0
0
34
105
3.34
9.27
1.6
1.6
—
—
—
0
0
146
876
1.82
8.99
7.1
5.7
1.06
1.03
mmol/l
0.37
137
800
101
548
1.97
8.43
1.9
1.6
—
—
—
0
0
31
97
3.29
8.29
1.6
1.3
—
—
—
0
0
112
638
1.88
8.09
1.9
1.6
—
—
—
0
0
102
574
1.90
7.63
1.9
2.8
66.40
66.10
g/l
0.14
90
525
104
597
1.86
7.32
2.5
2.3
0.19
0.20
g/l
0.85
99
548
30
101
3.05
7.15
1.5
1.2
2010.47
1460.60
e6/l
0.66
19
65
161
1056
1.66
7.12
3.4
2.6
2.15
2.24
g/l
1.16
150
972
113
675
1.79
6.98
2.8
4.5
21.12
26.53
ug/l
0.13
97
576
27
87
3.18
6.92
1.2
1.7
0.92
0.87
g/l
0.07
20
74
169
1130
1.64
6.91
3.5
2.6
10.63
12.38
umol/l
2.96
159
1046
233
1684
1.55
6.85
9.9
6.3
—
—
—
0
0
151
988
1.66
6.71
3.5
2.6
20.06
22.37
%
1.38
142
919
236
1718
1.54
6.69
3.0
2.3
2.83
3.03
mg/l
0.66
207
1481
352
2790
1.48
6.61
8.8
6.5
1.20
1.21
mmol/l
1.00
326
2553
13
16
8.24
6.35
1.5
1.5
—
—
—
0
0
62
314
2.06
6.27
1.8
1.3
112.98
352.89
u/ml
1.75
56
289
15
24
6.35
6.18
1.9
2.1
1287.67
876.04
u/ml
0.39
15
24
17
32
5.41
6.18
1.4
1.7
802.00
471.52
e6/l
0.67
12
27
114
707
1.72
6.17
2.2
1.8
—
—
—
0
0
345
2751
1.46
6.14
6.5
5.2
33.45
34.89
g/l
4.27
319
2566
25
83
3.08
6.12
1.6
1.2
—
—
—
0
0
86
498
1.82
5.88
1.5
1.4
—
—
—
0
0
67
358
1.96
5.85
1.8
1.5
—
—
—
0
0
26
91
2.92
5.83
1.6
1.2
30071.71
24274.22
e6/l
0.09
14
51
17
46
3.76
5.67
1.4
1.2
—
—
—
0
0
65
352
1.93
5.47
1.6
1.9
1.58
1.54
g/l
0.12
59
316
110
698
1.67
5.46
4.5
3.6
5.81
5.81
kpa
0.02
105
678
106
667
1.68
5.43
3.8
3.1
4.20
5.76
e9/l
1.01
79
570
376
3098
1.42
5.36
9.6
7.3
1.21
1.21
mmol/l
0.44
333
2642
75
429
1.83
5.34
4.3
4.9
—
—
—
0
0
122
801
1.62
5.29
8.8
7.4
1.16
1.01
mmol/l
0.16
107
646
123
810
1.62
5.27
8.8
7.4
5.07
5.10
kpa
0.12
117
776
123
811
1.62
5.24
8.8
7.3
11.43
11.63
kpa
0.11
118
778
17
49
3.53
5.20
1.4
1.3
—
—
—
0
0
106
675
1.66
5.18
4.7
3.6
2.04
2.03
mmol/l
0.00
91
567
29
115
2.58
5.18
1.5
1.3
59.13
57.30
mmol/l
0.08
23
97
26
99
2.68
5.03
1.3
1.4
—
—
—
0
0
243
1872
1.44
4.95
3.9
3.1
33.11
35.70
u/l
0.48
231
1771
92
574
1.69
4.86
11.0
8.3
—
—
—
0
0
497
4352
1.40
4.71
15.6
8.4
82.25
81.75
u/l
0.06
484
4094
27
109
2.53
4.67
1.4
1.2
—
—
—
0
0
125
852
1.56
4.62
2.9
2.5
1.81
1.79
%
0.09
111
765
101
655
1.62
4.60
2.9
2.7
66.26
67.34
e9/l
0.11
72
495
107
707
1.60
4.51
4.5
3.6
7.38
7.38
ph
0.05
62
444
12
24
5.06
4.33
1.2
1.2
—
—
—
0
0
117
800
1.55
4.26
9.1
7.5
7.42
7.41
ph
0.30
70
472
16
51
3.18
4.23
1.5
1.2
—
—
—
0
0
70
424
1.72
4.14
10.5
8.6
24.27
24.42
mmol/l
0.14
70
412
39
196
2.04
4.10
2.7
2.1
2.83
8.26
iu/ml
1.72
12
49
302
2478
1.36
4.07
21.5
12.3
0.00
0.00
e9/l
0.98
237
2015
127
898
1.50
3.95
1.4
1.3
56.78
33.30
iu/ml
0.44
38
282
143
1040
1.46
3.86
1.5
1.4
2.69
2.62
g/l
0.14
95
619
237
1894
1.36
3.72
3.1
2.5
62.37
61.50
u/l
0.07
224
1767
33
162
2.08
3.71
2.5
1.5
0.23
0.23
g/l
0.14
33
157
91
608
1.56
3.67
8.0
7.0
11.01
11.17
mmol/l
0.07
86
578
54
315
1.77
3.66
5.0
3.9
—
—
—
0
0
77
497
1.61
3.59
6.8
4.4
0.45
0.61
%
0.50
37
165
264
2155
1.34
3.58
4.2
3.3
2649.35
1959.93
ng/l
1.21
237
1858
164
1244
1.41
3.51
2.2
1.7
1.23
1.50
mg/l
0.79
129
992
235
1892
1.35
3.48
5.8
4.3
7.40
7.40
ph
0.12
180
1369
25
113
2.25
3.45
1.3
1.3
4.26
3.81
mmol/l
0.58
25
104
104
726
1.50
3.44
1.4
1.2
—
—
—
0
0
72
467
1.60
3.31
1.8
2.5
—
—
—
0
0
165
1265
1.39
3.30
5.3
4.2
843.96
330.55
ng/l
0.88
140
1079
239
1943
1.33
3.29
3.8
2.6
—
—
—
0
0
17
66
2.61
3.23
1.1
1.1
—
—
—
0
0
76
503
1.57
3.21
1.7
1.5
—
—
—
0
0
45
260
1.78
3.18
1.2
1.3
—
—
—
0
0
135
1767
0.71
3.16
3.1
3.4
—
—
—
0
0
52
315
1.70
3.12
2.5
2.6
35.60
16.62
au/ml
—
5
22
158
1218
1.37
3.05
2.0
1.8
1098.89
1146.64
nmol/l
0.28
118
918
74
493
1.55
3.05
7.4
4.5
0.00
0.15
%
3.72
33
151
98
695
1.47
3.01
2.9
2.9
4.95
8.76
umol/l
4.69
85
625
14
51
2.78
3.00
1.6
1.1
—
—
—
0
0
284
2391
1.30
2.99
4.0
3.8
6.34
6.23
ph
0.90
151
1367
15
57
2.66
2.98
1.9
1.9
—
—
—
0
0
77
521
1.53
2.96
7.1
4.4
0.54
0.86
%
1.33
36
180
31
163
1.94
2.94
2.5
2.1
118.68
127.78
g/l
1.01
19
129
19
83
2.32
2.86
1.3
1.4
155.90
160.54
au/ml
—
10
23
13
47
2.80
2.82
2.5
2.6
—
19.90
—
0
7
21
97
2.20
2.79
1.3
1.4
—
—
—
0
0
19
86
2.24
2.65
1.1
1.0
—
—
—
0
0
11
35
3.17
2.65
1.0
1.1
—
—
—
0
0
351
3069
1.27
2.65
18.7
18.0
1.28
1.35
inr
1.51
310
2597
255
2145
1.28
2.64
2.5
2.3
—
—
—
0
0
112
835
1.40
2.64
1.4
1.3
15.08
12.89
u/ml
0.10
34
321
15
61
2.49
2.63
6.7
3.5
—
—
—
0
0
12
41
2.96
2.63
1.4
1.1
—
—
—
0
0
10
30
3.36
2.61
1.0
1.0
—
—
—
0
0
250
2102
1.28
2.59
3.4
3.5
2.34
2.35
mmol/l
0.88
215
1887
38
223
1.74
2.59
1.8
1.7
0.33
0.34
mg/l
0.04
21
100
27
142
1.93
2.58
1.3
1.2
—
—
—
0
0
296
2542
1.27
2.58
4.2
3.0
183.42
154.44
ug/l
0.74
276
2347
12
44
2.75
2.55
1.4
1.2
—
—
—
0
0
12
44
2.75
2.55
1.3
1.3
—
—
—
0
0
230
1922
1.28
2.49
2.5
2.1
264.31
293.65
u/l
0.14
217
1816
15
63
2.41
2.47
3.1
2.4
—
—
—
0
0
36
211
1.74
2.47
1.4
3.7
2.51
3.18
ratio
0.31
23
123
190
1554
1.30
2.42
3.6
2.9
363.76
364.32
umol/l
0.02
164
1345
78
554
1.45
2.41
5.2
4.2
7.37
7.35
ph
0.40
61
397
47
299
1.61
2.39
2.0
1.8
—
—
—
0
0
23
119
1.96
2.32
2.4
1.7
—
—
—
0
0
76
541
1.45
2.32
2.3
2.0
397.16
386.31
nmol/l
0.23
68
502
38
233
1.66
2.24
1.4
3.9
49.04
83.40
mg/l
0.71
32
198
38
233
1.66
2.24
1.4
3.9
32.90
51.00
mg/l
0.79
33
198
133
1048
1.33
2.22
4.3
3.4
1.55
1.55
e6/l
0.00
75
559
11
41
2.71
2.21
1.4
1.4
—
—
—
0
0
71
504
1.45
2.21
8.0
4.8
0.00
0.15
%
1.56
29
144
177
1451
1.29
2.21
3.6
2.5
—
—
—
0
0
268
2312
1.24
2.17
5.7
4.3
84.55
134.21
e6/l
0.55
202
1722
165
1344
1.29
2.16
4.4
4.1
—
0.25
—
0
20
7
19
3.71
2.15
2.3
3.7
74.36
52.24
%
—
7
19
11
42
2.64
2.15
1.6
1.5
—
—
—
0
0
28
160
1.78
2.12
1.3
1.2
—
—
—
0
0
27
153
1.79
2.10
5.9
3.8
—
—
—
0
0
464
5012
0.81
2.09
5.3
5.1
1.48
1.42
mmol/l
2.28
427
4568
139
1112
1.31
2.08
4.1
3.3
1.16
1.09
e6/l
0.06
84
626
75
545
1.42
2.07
3.8
3.3
251.32
246.47
ng/l
0.03
66
499
17
324
0.51
2.03
1.3
1.4
—
—
—
0
0
11
44
2.52
2.02
1.5
1.5
—
—
—
0
0
43
281
1.56
1.99
2.4
2.4
0.00
3.05
estimate
0.49
12
82
20
105
1.93
1.97
2.6
1.9
—
—
—
0
0
535
5679
0.81
1.95
49.0
28.1
252.17
239.72
e9/l
3.28
526
5553
5
11
4.57
1.94
1.0
1.0
—
—
—
0
0
5
11
4.57
1.94
1.0
1.1
—
—
—
0
0
536
5683
0.81
1.89
49.0
28.1
7.50
6.95
e9/l
2.36
527
5535
14
65
2.18
1.89
1.3
1.2
—
—
—
0
0
21
114
1.87
1.89
1.4
1.3
23.56
17.91
e6/l
0.13
16
86
536
5681
0.81
1.87
48.9
28.0
4.30
4.42
e12/l
4.70
525
5533
536
5681
0.81
1.87
49.9
28.6
38.87
39.75
%
3.31
531
5591
6
17
3.55
1.84
1.0
2.1
—
—
—
0
0
393
3574
1.20
1.81
7.5
5.2
6.62
6.81
mmol/l
1.12
376
3406
483
5164
0.82
1.79
5.9
6.0
2.46
2.56
mmol/l
1.66
445
4708
282
2492
1.21
1.74
2.7
2.4
78.09
77.28
nmol/l
0.16
255
2212
8
30
2.68
1.72
5.6
4.0
114.63
137.87
nmol/l
—
8
30
472
5049
0.83
1.72
5.3
5.2
4.37
4.43
mmol/l
0.63
435
4633
5
13
3.86
1.71
1.0
1.2
—
—
—
0
0
23
133
1.75
1.71
2.5
1.9
—
—
—
0
0
23
133
1.75
1.71
2.5
1.9
—
—
—
0
0
222
2540
0.82
1.68
5.1
5.8
6.21
5.02
ug/l
0.12
198
2244
10
41
2.46
1.64
1.5
1.1
1.39
1.16
promille
—
10
32
12
56
2.16
1.61
1.6
1.2
—
—
—
0
0
19
107
1.80
1.56
1.5
1.3
73.36
244.68
miu/ml
—
9
44
5
15
3.35
1.52
2.0
1.5
31.80
32.00
%
—
5
15
376
3442
1.18
1.51
5.6
3.4
59.64
53.62
u/l
0.56
358
3218
6
21
2.87
1.51
1.0
1.0
—
—
—
0
0
6
21
2.87
1.51
1.0
1.2
28.17
22.45
%
—
6
11
41
285
1.46
1.48
1.2
1.2
121.26
133.23
u/ml
0.06
16
105
22
132
1.69
1.47
2.6
1.9
—
—
—
0
0
156
1321
1.23
1.46
3.5
3.2
533.79
542.20
mosm/kgh2o
0.21
143
1155
5
16
3.14
1.44
1.0
3.2
3.40
5.31
ug/l
—
5
16
22
133
1.67
1.44
2.5
1.6
—
—
—
0
0
293
2637
1.18
1.43
3.9
2.9
—
—
estimate
—
0
0
21
126
1.69
1.41
2.6
1.9
—
—
—
0
0
280
2514
1.18
1.40
5.4
4.2
40.62
43.69
ng/l
0.24
210
1947
208
1822
1.19
1.38
4.6
3.6
0.59
0.49
e6/l
0.27
166
1394
9
41
2.21
1.37
3.2
2.7
—
—
—
0
0
6
23
2.62
1.37
21.8
16.7
726.17
926.61
nmol/l
—
6
23
452
4809
0.85
1.36
4.5
4.4
1.20
1.27
mmol/l
1.52
410
4338
35
241
1.47
1.35
1.9
2.5
10.87
10.98
g/l
0.05
25
211
13
68
1.93
1.34
1.2
1.2
2.63
7.10
u/ml
—
8
29
534
5603
0.85
1.34
42.2
24.9
86.34
85.51
umol/l
0.12
529
5510
11
54
2.05
1.33
1.5
1.2
—
—
—
0
0
327
2983
1.17
1.33
4.7
4.2
0.00
0.00
estimate
-0.00
55
669
9
44
2.06
1.27
1.0
1.1
—
—
—
0
0
237
2114
1.18
1.26
4.9
3.7
35.71
109.93
e6/l
1.60
197
1667
72
567
1.30
1.26
3.5
2.5
34.17
34.98
u/l
0.08
65
469
172
1968
0.84
1.26
3.7
3.5
77.85
56.83
mg/l
0.43
116
1330
331
3033
1.16
1.25
4.8
4.3
0.00
0.47
estimate
0.51
54
644
25
163
1.55
1.24
1.6
1.4
331.39
287.18
ug/g
0.40
17
94
178
2028
0.84
1.24
4.4
4.2
12.25
9.69
mg/mmol
0.33
114
1323
43
314
1.39
1.23
1.3
1.2
—
—
—
0
0
32
221
1.47
1.23
4.0
3.2
368.21
272.19
mg/l
0.32
14
88
513
5386
0.86
1.22
26.9
16.7
—
—
—
0
0
11
56
1.98
1.22
1.3
1.3
—
—
—
0
0
10
49
2.05
1.22
2.1
2.1
—
—
—
0
0
213
1893
1.17
1.18
2.1
1.8
19.25
20.07
nmol/l
0.38
186
1602
16
94
1.72
1.18
1.1
1.1
—
—
—
0
0
61
476
1.31
1.16
4.5
4.0
98.13
91.21
ng/l
0.20
51
416
26
175
1.50
1.14
4.3
8.4
1.76
1.47
mmol/l
0.16
21
155
327
3010
1.15
1.14
4.8
4.3
0.00
2.37
estimate
0.50
59
687
17
104
1.65
1.10
1.3
1.2
338.90
274.35
u/ml
—
10
51
474
4988
0.87
1.10
6.6
6.9
40.10
40.11
mmol/mol
0.01
439
4606
14
81
1.74
1.09
1.2
1.1
—
—
—
0
0
138
1191
1.19
1.08
8.0
4.8
—
—
—
0
0
11
59
1.88
1.07
4.5
3.3
7.45
6.35
nmol/l
0.10
11
59
128
1472
0.84
0.99
3.4
3.3
0.72
0.83
ug/l
1.04
85
998
23
156
1.49
0.99
4.2
2.5
87.13
88.59
%
0.52
23
150
71
578
1.25
0.99
2.8
2.3
264.09
148.34
ug/g
0.87
56
464
36
479
0.74
0.99
5.7
4.0
—
—
—
0
0
482
5050
0.88
0.99
5.6
5.4
5.94
6.07
mmol/l
1.13
443
4552
9
49
1.85
0.99
1.2
1.2
—
—
—
0
0
23
157
1.48
0.97
1.1
1.6
—
—
—
0
0
407
3839
1.13
0.92
6.6
5.1
5653.73
2389.19
e6/l
0.25
11
74
6
28
2.15
0.91
1.7
2.0
41.87
40.25
g/l
—
6
28
6
28
2.15
0.91
1.5
1.3
—
—
—
0
0
19
277
0.68
0.90
1.7
1.8
2.65
3.49
mmol/l
3.09
11
209
8
43
1.87
0.87
1.5
1.3
—
—
—
0
0
6
30
2.01
0.87
1.0
1.1
—
9.10
—
0
8
169
1512
1.15
0.86
3.6
2.8
3.96
4.66
e6/l
0.55
156
1384
21
145
1.46
0.85
8.8
4.4
3.79
2.54
mmol/l
0.80
14
95
16
104
1.55
0.85
4.8
3.1
4.40
4.52
e9/l
0.08
16
104
8
45
1.79
0.84
1.0
1.9
—
—
—
0
0
37
284
1.32
0.83
1.3
1.2
—
—
—
0
0
66
547
1.23
0.81
2.3
2.3
0.00
0.00
estimate
-0.00
11
102
531
5498
0.89
0.79
21.9
12.5
24.20
25.73
u/l
1.58
523
5314
0
26
0.00
0.78
0.0
3.3
—
—
—
0
0
10
59
1.70
0.76
1.1
1.3
29.37
28.71
ng/l
—
10
59
21
150
1.41
0.74
1.8
1.6
8150.00
14478.52
e6/l
0.79
16
111
9
55
1.64
0.73
1.1
1.1
—
—
—
0
0
5
25
2.01
0.72
1.6
1.8
38.00
54.46
ug/l
—
5
25
14
92
1.53
0.72
4.0
3.1
—
—
—
0
0
9
56
1.61
0.72
1.9
1.7
9.20
10.48
%
—
9
56
10
60
1.68
0.72
1.1
1.2
—
—
—
0
0
68
574
1.20
0.72
2.6
2.6
6.57
6.90
ug/l
0.07
52
501
86
743
1.18
0.71
1.4
1.4
—
—
—
0
0
38
303
1.27
0.68
3.9
3.0
—
—
—
0
0
7
43
1.63
0.67
1.0
1.2
76.14
95.35
pmol/l
—
7
43
292
2743
1.10
0.66
2.7
2.3
87.13
93.78
pmol/l
1.87
179
1480
531
5475
0.90
0.65
38.6
23.0
4.00
4.01
mmol/l
0.36
524
5348
146
1321
1.13
0.65
1.7
1.8
470.02
5258743.48
pmol/l
0.50
122
1084
5
29
1.73
0.64
1.2
1.0
—
—
—
0
0
8
49
1.64
0.62
1.3
1.4
—
—
—
0
0
15
105
1.44
0.60
1.5
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
3.3
—
—
—
0
0
532
5473
0.91
0.58
38.3
22.8
138.86
139.61
mmol/l
6.86
526
5353
6
35
1.72
0.57
1.3
1.1
236.33
247.31
mg/l
—
6
29
188
2024
0.91
0.56
3.7
3.4
6.66
7.59
mmol/l
2.44
161
1693
11
74
1.49
0.53
3.0
1.9
85.44
89.73
%
0.67
11
74
9
135
0.66
0.52
1.1
1.1
—
—
—
0
0
40
477
0.83
0.52
3.8
3.1
6.25
6.08
ph
0.59
28
347
468
4828
0.92
0.51
5.6
5.0
1.85
1.99
mu/l
1.87
424
4362
19
144
1.33
0.51
3.6
4.0
33.06
32.03
mg/l
0.03
11
107
9
65
1.39
0.50
1.8
1.0
—
—
—
0
0
9
65
1.39
0.50
1.8
1.0
—
—
—
0
0
6
41
1.47
0.50
1.3
1.9
79.67
106.11
ng/l
—
6
41
6
41
1.47
0.50
2.0
1.5
84.00
64.68
%
—
6
28
18
136
1.33
0.49
5.2
3.1
58.41
60.19
%
0.29
18
136
7
109
0.64
0.48
1.0
1.1
1.61
1.54
g/l
—
7
109
8
117
0.68
0.46
1.1
1.2
0.79
0.89
g/l
—
8
117
141
1303
1.10
0.45
3.6
3.2
2.46
2.46
mmol/l
0.16
122
1163
42
491
0.85
0.45
1.7
1.6
—
—
—
0
0
23
183
1.26
0.45
4.3
2.5
7.23
7.84
kpa
1.33
23
178
21
166
1.27
0.43
1.3
1.2
—
—
—
0
0
199
2112
0.92
0.43
5.8
4.0
—
0.75
—
0
8
11
78
1.42
0.43
1.1
1.3
—
—
—
0
0
70
624
1.13
0.42
1.4
1.3
—
—
—
0
0
17
217
0.78
0.42
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
2.2
1.5
9.40
1.25
%
—
5
27
0
16
0.00
0.41
0.0
1.2
—
7.64
—
0
16
144
1340
1.09
0.41
4.8
4.4
1.02
1.02
kg/l
0.38
97
918
0
17
0.00
0.40
0.0
5.9
—
49.71
—
0
12
22
177
1.25
0.40
4.3
3.6
2.72
1.85
index
0.19
14
99
12
158
0.76
0.37
1.6
1.7
—
—
—
0
0
24
198
1.22
0.36
4.2
2.9
1.46
1.71
mg/l
0.97
24
174
121
1124
1.09
0.36
1.4
1.3
3.95
1.43
u/ml
0.44
23
281
11
146
0.75
0.36
1.0
1.1
—
—
—
0
0
198
2084
0.93
0.35
2.1
2.0
1.22
1.32
mmol/l
1.29
176
1717
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
43
377
1.15
0.34
1.2
1.2
—
—
—
0
0
16
127
1.27
0.33
1.4
1.6
736.13
284.06
mu/l
0.75
16
118
384
3951
0.94
0.33
4.6
4.0
15.16
14.96
pmol/l
0.80
347
3543
11
83
1.33
0.32
5.7
4.6
351.09
338.84
umol/l
0.15
11
73
14
174
0.80
0.30
1.3
1.9
48.79
42.10
nmol/l
0.51
14
166
12
95
1.27
0.26
1.7
1.9
32.50
33.02
pg
0.19
12
95
12
148
0.81
0.24
1.2
1.2
—
—
—
0
0
24
208
1.16
0.24
2.7
2.8
153.94
62.08
u/ml
0.44
24
200
5
42
1.19
0.21
1.0
1.0
211.20
279.33
ng/l
—
5
27
0
12
0.00
0.21
0.0
1.1
—
0.82
—
0
5
5
43
1.16
0.21
1.6
2.0
—
—
—
0
0
157
1634
0.95
0.21
4.5
3.7
0.00
0.07
estimate
0.86
48
519
13
108
1.21
0.20
4.2
3.5
11.73
10.04
pmol/l
0.16
13
108
5
67
0.74
0.17
1.0
2.3
—
—
—
0
0
140
1449
0.96
0.15
1.3
1.4
—
—
—
0
0
33
304
1.09
0.14
2.2
2.5
—
—
—
0
0
528
5325
0.97
0.11
36.6
19.0
28.92
27.53
mg/l
0.47
485
4520
14
153
0.91
0.07
1.5
2.5
130.50
99.92
ug/min
—
6
93
15
163
0.92
0.07
15.9
12.1
—
—
—
0
0
26
272
0.95
0.04
1.8
2.0
—
—
—
0
0
18
170
1.06
0.04
1.7
1.5
11.36
13.30
u/ml
—
5
25
10
109
0.92
0.04
1.2
1.3
—
—
—
0
0
230
2282
1.01
0.03
4.7
4.3
0.04
0.05
estimate
0.04
46
558
191
1925
0.99
0.03
4.1
3.5
—
—
—
0
0
35
359
0.97
0.02
1.1
1.4
—
—
—
0
0
18
185
0.97
0.00
3.3
4.9
—
—
—
0
0
13
134
0.97
0.00
1.2
1.9
170.08
221.57
pmol/l
1.15
13
125
17
168
1.01
0.00
4.4
3.3
7.51
7.49
mmol/l
0.01
17
163
172
1716
1.00
0.00
5.2
4.3
0.00
0.01
estimate
0.78
52
593
0
9
0.00
0.00
0.0
3.7
—
—
—
0
0
5
53
0.94
0.00
8.2
2.8
8.10
7.83
mmol/l
—
5
53
0
7
0.00
-0.00
0.0
1.7
—
72.29
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
57
0.88
-0.00
1.4
2.6
1574.60
1152.64
mg
—
5
57
5
52
0.96
-0.00
7.2
2.9
13.58
16.04
%
—
5
52
0
7
0.00
-0.00
0.0
1.3
—
0.41
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
71
0.99
-0.00
1.6
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
0.59
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
1.90
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
46.74
—
0
8
0
8
0.00
-0.00
0.0
3.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_RESP_TUBERCU_CONF_WIDE – Respiratory tuberculosis, confirmed, including avohilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).