Use of antiglaucoma preparations and miotics

H7_GLAUCOMAMEDICATION

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC S01EA

1 out of 7 registries used, show all original rules.

3827

4. Check minimum number of events

Min. number of events 3
3827

5. Include endpoints

None

3827

6. Filter based on genotype QC (FinnGen only)

3363

Control definitions (FinnGen only)

Control exclude
H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31315 19313 11757
Only index persons 26241 16426 9815
Unadjusted period prevalence (%)
Whole population 0.47 0.55 0.33
Only index persons 0.52 0.60 0.37
Median age at first event (years)
Whole population 71.87 73.07 69.86
Only index persons 70.67 71.97 68.49

-FinnGen-

Key figures

All Female Male
Number of individuals 3363 1841 1522
Unadjusted period prevalence (%) 0.67 0.65 0.70
Median age at first event (years) 68.27 67.75 68.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3478
Matched controls
34780
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01ED02
ATC
betaxolol; ophthalmic
161.0
307.7
509
37
S01EE01
ATC
latanoprost; ophthalmic
157.6
307.7
2372
467
S01EE04
ATC
travoprost; ophthalmic
108.7
307.7
849
103
S01ED51
ATC
timolol, combinations; ophthalmic
408.7
307.7
3022
555
S01EC54
ATC
brinzolamide, combinations; ophthalmic
317.2
307.7
667
26
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
11.3
307.7
506
518
WX140
NOMESCO Finland
Parabulbar anesthesy
18.2
307.7
1040
796
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
1886.0
307.7
1054
8
S01EA02
ATC
dipivefrine; ophthalmic
1169.5
307.7
413
*
S01EA05
ATC
brimonidine; ophthalmic
8028.9
307.7
3146
41
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
1202.4
307.7
1188
15
ZXC20
NOMESCO Finland
Use of chemical agents
11.3
307.7
357
348
S01EC03
ATC
dorzolamide; ophthalmic
223.0
307.7
944
58
S01EX03, ,
ATC
205.6
307.7
1253
95
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.8
307.7
1020
1758
XCH00
NOMESCO Finland
Eye pressure measurement
11.7
307.7
643
661
H40.0
ICD-10 Finland
Glaucoma suspect
143.8
307.7
1048
104
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.2
307.7
2405
10536
CHD35
NOMESCO Finland
Laser goniopuncture
+∞
307.7
316
*
H40.11
ICD-10 Finland
Low pressure glaucoma
218.7
307.7
489
26
S01EC01
ATC
acetazolamide; systemic
148.0
307.7
1364
151
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
26.1
307.7
266
110
114
Kela drug reimbursment
Glaucoma
802.8
307.7
3249
604
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
24.1
307.7
245
109
CHD00
NOMESCO Finland
Laser trabeculoplasty
1836.4
307.7
600
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.6
307.7
1162
2156
XCH05
NOMESCO Finland
Eye pressure longterm registration
181.6
307.7
314
19
S01EE05
ATC
tafluprost; ophthalmic
75.9
307.7
1004
185
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.8
307.7
2512
12270
S01EB01
ATC
pilocarpine; ophthalmic
122.0
307.7
419
39
S01EA03
ATC
apraclonidine; ophthalmic
87.4
307.7
571
78
CS494
NOMESCO Finland
Other visual field testing
28.4
307.7
376
148
H40
ICD-10 Finland
Glaucoma
74.7
307.7
313
46
S01EC04
ATC
brinzolamide; ophthalmic
245.6
307.7
1838
158
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
307.7
633
*
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
4630.7
307.7
420
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.7
307.7
2529
12561
XCK00
NOMESCO Finland
Perimetry
38.2
307.7
1379
588
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
48.3
307.7
605
151
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.6
307.7
1328
3443
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
127.7
307.7
227
19
XCK10
NOMESCO Finland
Photography of fundus of eye
7.1
307.7
1028
1932
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
1469.4
307.7
1854
27
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
284.3
307.7
489
20
S01EE03
ATC
bimatoprost; ophthalmic
156.5
307.7
1051
96
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
+∞
307.7
434
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.5
307.7
1756
4180
CHC05
NOMESCO Finland
Iridotomy
101.6
307.7
356
39
H20.1
ICD-10 Finland
Chronic iridocyclitis
45.0
307.7
301
73
S01ED01
ATC
timolol; ophthalmic
113.7
307.7
1601
259
H40.9
ICD-10 Finland
Glaucoma, unspecified
287.5
307.7
635
27
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
307.7
596
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
294.0
278
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.8
269.5
544
1069
CHD99
NOMESCO Finland
Other filtering operation
2584.6
262.7
251
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.7
255.5
1070
3705
CS2P4
NOMESCO Finland
Optic nerve head imaging
75.0
254.7
137
19
F93
ICPC
Glaucoma
70.2
248.4
135
20
S01BA07
ATC
fluorometholone; ophthalmic
14.2
246.7
230
173
H25.1
ICD-10 Finland
Senile nuclear cataract
3.2
238.8
2011
10513
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.0
237.3
848
2622
H34.8
ICD-10 Finland
Other retinal vascular occlusions
9.0
228.7
293
351
S01BC03
ATC
diclofenac; ophthalmic
8.6
220.1
293
368
H26.2
ICD-10 Finland
Complicated cataract
14.8
210.2
190
135
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
207.4
197
*
CFW99
NOMESCO Finland
Other operation on conjunctiva
1014.5
197.9
192
*
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
344.4
196.7
197
6
Z3229
NOMESCO Finland
Other healthcare associate professional
4.0
190.7
634
1843
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
2048.4
190.3
183
*
H26.4
ICD-10 Finland
After-cataract
3.3
189.9
899
3294
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
7.7
184.9
270
377
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
20.2
181.7
140
72
WX142
NOMESCO Finland
Sub-tenon anesthesy
20.2
179.1
138
71
CKC12
NOMESCO Finland
Photocoagulation of retina
6.3
175.9
311
532
H21.0
ICD-10 Finland
Hyphaema
33.4
171.8
110
34
ZXA10
NOMESCO Finland
Bilateral
2.9
170.2
1076
4619
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
4.3
160.6
464
1210
H3603, E103,
ICD-10 Finland
28.5
160.5
108
39
S01BA04
ATC
prednisolone; ophthalmic
6.9
152.8
245
378
H43.1
ICD-10 Finland
Vitreous haemorrhage
7.2
149.2
230
340
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
21.2
144.7
109
53
H40.8
ICD-10 Finland
Other glaucoma
302.1
142.6
144
5
CKD40
NOMESCO Finland
Endophotocoagulation of retina
10.1
141.9
163
168
F38
ICPC
Eye, Other laboratory test NEC
9.2
141.6
175
199
ZXA05
NOMESCO Finland
Left side
2.5
139.8
1300
6658
H16.0
ICD-10 Finland
Corneal ulcer
5.2
137.5
296
606
S01BA01
ATC
dexamethasone; ophthalmic
5.4
135.7
284
567
H18.1
ICD-10 Finland
Bullous keratopathy
34.8
134.4
85
25
CKD20
NOMESCO Finland
Removal of vitreous body substitute
18.4
133.3
107
60
TCG10
NOMESCO Finland
Removal of sutures from cornea
18.6
131.7
105
58
H33.0
ICD-10 Finland
Retinal detachment with retinal break
5.9
131.4
248
450
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
1306.0
130.1
126
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
24.7
125.7
89
37
ZXA00
NOMESCO Finland
Right side
2.4
124.3
1336
7224
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
8.3
123.7
166
209
S01FA01
ATC
atropine; ophthalmic
18.8
122.2
97
53
H40.1
ICD-10 Finland
Primary open-angle glaucoma
252.8
119.7
122
5
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
15.6
113.9
99
65
S01FA04
ATC
cyclopentolate; ophthalmic
10.3
113.7
128
128
WX002
NOMESCO Finland
Sedation and analgesia
2.5
112.1
957
4633
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
110.0
105
*
Z94.7
ICD-10 Finland
Corneal transplant status
20.7
109.3
83
41
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
16.2
105.4
90
57
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
104.7
100
*
Z3231
NOMESCO Finland
Registered nurse
2.3
104.4
1221
6738
SPAT1009
SPAT
Measurement of intraocular pressure
9.1
103.1
128
146
CKD15
NOMESCO Finland
Injection of vitreous substitute
17.8
100.9
82
47
H3603, E113,
ICD-10 Finland
10.7
96.7
106
102
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
14.9
96.5
86
59
XCW10
NOMESCO Finland
Assessment of vision
8.1
96.4
131
167
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
+∞
96.3
92
*
S01BC05
ATC
ketorolac; ophthalmic
3.6
94.3
344
1043
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
93.1
89
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
27.9
93.0
63
23
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
6.9
90.1
141
211
CKC15
NOMESCO Finland
Panretinal photocoagulation
9.1
85.5
105
118
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.4
83.6
141
228
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
7.2
82.7
124
177
CHC03
NOMESCO Finland
Laser iridoplasty
+∞
82.6
79
*
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
8.0
82.2
113
146
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
21.4
81.5
61
29
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
7.1
79.8
122
178
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
796.3
79.7
78
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
7.2
78.9
118
168
3708
FHL
Trabeculectomy or equivalent
+∞
78.4
75
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
78.1
513
2160
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
31.7
76.8
50
16
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
76.3
73
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
105.0
75.2
82
8
CHD10
NOMESCO Finland
Trabeculectomy
+∞
72.1
69
*
H16.9
ICD-10 Finland
Keratitis, unspecified
6.6
71.6
117
183
H54.1
ICD-10 Finland
Severe visual impairment, binocular
28.6
71.4
48
17
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
29.8
70.8
47
16
H27.1
ICD-10 Finland
Dislocation of lens
11.7
69.0
71
62
CKC10
NOMESCO Finland
Local photocoagulation of retina
5.0
68.6
151
313
ZXE00
NOMESCO Finland
One hour or less
1.9
67.9
1436
9466
H40.12
ICD-10 Finland
Pigmentary glaucoma
343.8
67.8
68
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
12.7
67.6
66
53
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
144.9
67.2
71
5
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.9
67.1
339
1242
CG2T4
NOMESCO Finland
Topography assessment of cornea
9.0
66.2
82
93
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.7
66.0
221
630
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
11.3
64.9
68
61
H54.4
ICD-10 Finland
Blindness, monocular
19.1
62.3
49
26
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
8.3
59.9
79
97
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
59.5
57
*
F43
ICPC
Eye, Other diagnostic procedure
5.4
59.1
119
228
CFB00
NOMESCO Finland
Suture of conjunctiva
81.6
57.1
64
8
A10AA01, ,
ATC
4.7
56.9
135
298
H27.0
ICD-10 Finland
Aphakia
13.0
56.3
54
42
H3601, E103,
ICD-10 Finland
11.8
55.9
57
49
H26.02
ICD-10 Finland
Presenil cataract
4.7
55.4
130
284
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
10.5
55.3
61
59
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
4.6
54.5
132
296
H44.5
ICD-10 Finland
Degenerated conditions of globe
87.3
54.0
60
7
ZXD20
NOMESCO Finland
Day surgery
2.2
53.7
514
2533
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
10.5
53.5
59
57
A10AB01
ATC
insulin (human); parenteral
3.7
53.5
178
505
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
4.8
53.1
122
262
S01EX
ATC
Other antiglaucoma preparations
+∞
52.2
50
*
S01GX01
ATC
cromoglicic acid; ophthalmic
2.0
52.0
628
3380
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.0
51.9
149
381
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
51.7
1352
9290
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
51.2
49
*
F99
ICPC
Eye/adnexa disease other
7.9
51.1
70
90
H35.36
ICD-10 Finland
Macular cyst
7.4
50.9
74
102
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
4.8
50.8
115
244
S01AD03
ATC
aciclovir; ophthalmic
3.4
50.0
185
562
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
175.9
50.0
52
*
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
494.8
49.5
49
*
CKD60
NOMESCO Finland
Anterior vitrectomy
5.9
48.8
88
152
H18.2
ICD-10 Finland
Other corneal oedema
16.8
47.9
40
24
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
7.4
47.5
69
95
Z2221
NOMESCO Finland
Medical doctor
1.8
46.2
980
6301
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
9.9
45.4
52
53
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.6
45.4
155
447
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
5.3
45.3
91
174
S01AX11
ATC
[U] ofloxacin
2.9
45.1
217
771
H36.01
ICD-10 Finland
Diabetic maculopathy
5.3
44.7
91
176
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
64.6
44.2
51
8
CFD10
NOMESCO Finland
Repair of conjunctiva
72.3
44.1
50
7
A10AA02, ,
ATC
3.1
43.5
189
633
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.1
43.3
92
185
H57.1
ICD-10 Finland
Ocular pain
3.5
42.9
152
449
H33.4
ICD-10 Finland
Traction detachment of retina
17.7
42.9
35
20
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.0
42.4
192
659
H04AA01
ATC
glucagon; nasal, parenteral
5.3
40.9
83
160
S01EX05
ATC
netarsudil; ophthalmic
+∞
40.7
39
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
9.7
40.4
47
49
XCD20
NOMESCO Finland
Photoangiography of eye
3.8
37.7
115
307
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
10.9
37.3
40
37
H3600, E103,
ICD-10 Finland
8.3
36.0
47
57
H25.8
ICD-10 Finland
Other senile cataract
1.8
35.0
623
3765
H01.0
ICD-10 Finland
Blepharitis
2.5
34.3
220
905
H20.8
ICD-10 Finland
Other iridocyclitis
10.4
34.2
38
37
CD2S4
NOMESCO Finland
Photography of eye
8.3
34.2
45
55
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
33.9
1337
9904
T89
ICPC
Diabetes insulin dependent
3.1
33.3
146
492
A10AB04
ATC
insulin lispro; parenteral
3.4
33.1
120
360
H25.0
ICD-10 Finland
Senile incipient cataract
2.1
32.4
325
1616
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
88.4
31.8
35
*
CG2S4
NOMESCO Finland
Photography of cornea
8.6
31.4
40
47
H26.3
ICD-10 Finland
Drug-induced cataract
7.3
30.9
45
62
H52.1
ICD-10 Finland
Myopia
3.7
30.3
95
259
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.9
29.7
65
134
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
29.2
456
2638
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
29.2
28
*
H18.8
ICD-10 Finland
Other specified disorders of cornea
7.5
28.9
41
55
L04AB04
ATC
adalimumab; parenteral
4.6
28.7
69
154
A10AC01
ATC
insulin (human); parenteral
2.0
28.2
343
1828
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.6
27.2
89
250
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
7.2
27.1
40
56
127
Kela drug reimbursment
Transplant complication
5.1
26.8
56
111
H02.4
ICD-10 Finland
Ptosis of eyelid
2.8
26.8
132
475
A10AB05
ATC
insulin aspart; parenteral
2.0
26.2
309
1627
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.6
25.8
49
89
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
262.5
25.7
26
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.6
25.5
155
621
S01XA18
ATC
ciclosporin; ophthalmic
6.2
25.3
43
70
L04AX03
ATC
methotrexate; systemic
2.0
25.2
305
1620
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.6
25.2
83
234
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
9.2
24.7
30
33
H31.4
ICD-10 Finland
Choroidal detachment
43.2
24.6
30
7
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
7.4
24.2
35
48
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.0
23.9
42
71
H54.5
ICD-10 Finland
Severe visual impairment, monocular
6.5
23.4
38
59
S01FA02
ATC
scopolamine; ophthalmic
4.6
23.3
55
121
CS444, ,
SPAT
33.6
23.3
30
9
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.2
23.1
204
964
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
54.4
23.1
27
5
A10AE04
ATC
insulin glargine; parenteral
1.8
22.9
375
2193
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.6
22.9
54
119
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
2.5
22.6
140
566
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
45.3
22.4
27
6
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.2
22.2
45
87
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
22.1
383
2276
3711
FHL
Cyclodiateria or cryocoagulation
+∞
21.9
21
*
3652B
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[KROONINEN AHDASKULMAGLAUKOOMA]
+∞
21.9
21
*
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
62.9
21.9
25
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
21.6
834
6029
H44.4
ICD-10 Finland
Hypotony of eye
115.8
21.6
23
*
J01DB01
ATC
cefalexin; oral
1.5
21.0
2590
23116
Q15.0
ICD-10 Finland
Congenital glaucoma
+∞
20.8
20
*
3719
FHL
Other measure in this category
+∞
20.8
20
*
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
+∞
20.8
20
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.2
20.6
35
57
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
6.2
20.6
35
57
CGG60
NOMESCO Finland
Reinforcement of sclera using graft
211.2
20.6
21
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
20.4
1712
14236
F29
ICPC
Eye symptom/complaint other
1.8
20.4
328
1906
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
7.5
20.4
29
39
A10AE05
ATC
insulin detemir; parenteral
2.1
20.3
201
993
H53.4
ICD-10 Finland
Visual field defects
3.0
20.2
92
317
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
20.1
2008
17176
Z94.0
ICD-10 Finland
Kidney transplant status
5.0
20.0
42
84
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
6.1
19.8
34
56
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
19.8
19
*
S01EB02
ATC
carbachol; ophthalmic
+∞
19.8
19
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
5.9
19.6
35
60
L04AD02
ATC
tacrolimus; systemic
5.7
19.4
36
64
CKC70
NOMESCO Finland
Circular buckling of sclera
6.5
19.2
31
48
V03AE02
ATC
sevelamer; oral
6.5
19.2
31
48
A98
ICPC
Health maint/preventive medicine
1.6
18.9
2959
27306
37512
ICD-8 Finland
Glaucoma, Chronicum capsulare
+∞
18.8
18
*
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
+∞
18.8
18
*
L04AA06
ATC
mycophenolic acid; systemic
3.6
18.7
62
176
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
6.8
18.7
29
43
N02BE01
ATC
paracetamol; systemic, rectal
1.5
18.6
2938
27087
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
18.8
18.6
28
15
H18.6
ICD-10 Finland
Keratoconus
6.6
18.3
29
44
L04AA01
ATC
[U] ciclosporin
3.8
18.2
56
151
F28
ICPC
Limited function/disability (F)
4.8
18.2
41
87
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
2.6
18.0
106
419
Z5132
NOMESCO Finland
Nursing associate professional
5.3
18.0
36
69
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
13.7
17.7
30
22
CFW10
NOMESCO Finland
Conjunctival manipulation with a needle (needling)
+∞
17.7
17
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
6.2
17.6
30
49
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
95.6
17.6
19
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
28.9
17.4
23
8
H54.0
ICD-10 Finland
Blindness, binocular
17.0
17.4
27
16
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
24.1
17.3
24
10
C08CA01
ATC
amlodipine; oral
1.4
17.2
1486
12291
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
6.2
17.2
29
47
TK800
NOMESCO Finland
Hemodialysis
2.9
17.1
81
286
H30.2
ICD-10 Finland
Posterior cyclitis
12.6
17.1
30
24
WX144
NOMESCO Finland
Subconjunctival anesthesy
3.3
17.1
65
202
H3601, E113,
ICD-10 Finland
2.9
17.0
79
276
H3603, E107,
ICD-10 Finland
50.3
17.0
20
*
A10AD01
ATC
insulin (human); parenteral
2.6
16.9
99
390
CDC00
NOMESCO Finland
Enucleation of eye
63.6
16.7
19
*
R3120
NOMESCO Finland
Training in mobility skills
6.5
16.6
27
42
CKC60
NOMESCO Finland
Local buckling of sclera using implant
4.9
16.6
36
74
H36.00
ICD-10 Finland
Diabetic background retinopathy
3.5
16.6
57
166
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.4
16.5
115
492
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
3.8
16.3
49
130
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
1.8
16.3
235
1321
H02AB06
ATC
prednisolone; systemic
1.3
16.1
1540
12899
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
16.0
175
897
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.4
16.0
58
175
CKD50
NOMESCO Finland
Endodiathermy of retina
18.6
16.0
24
13
H34.1
ICD-10 Finland
Central retinal artery occlusion
4.3
15.9
40
93
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
4.1
15.9
43
106
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.0
15.8
69
233
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.7
15.7
298
1812
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
15.5
995
7815
H18.4
ICD-10 Finland
Corneal degeneration
5.2
15.3
31
60
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
15.2
2307
20610
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
15.2
757
5690
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
11.3
15.2
28
25
S01BA09
ATC
clobetasone; ophthalmic
17.8
15.1
23
13
H33.3
ICD-10 Finland
Retinal breaks without detachment
2.3
15.1
115
512
CWW99
NOMESCO Finland
Other reoperation on eye and adjacent structures
45.2
15.1
18
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
3.9
15.0
44
115
E0000UV, ,
ATC
1.3
14.9
1264
10362
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.1
14.9
62
204
H3603, E109,
ICD-10 Finland
56.9
14.8
17
*
J01CA04
ATC
amoxicillin; systemic
1.4
14.7
2429
21920
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
4.4
14.7
36
82
3703
FHL
Laser operation on ventricular angle under general anesthesia
+∞
14.6
14
*
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
14.6
14
*
CHB30
NOMESCO Finland
Goniotomy
+∞
14.6
14
*
NHQ40
NOMESCO Finland
Amputation of toe
2.6
14.1
80
311
S01KA02
ATC
hypromellose; ophthalmic
2.6
14.1
80
311
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
4.6
14.0
33
73
SPAT1014
SPAT
Treatment of eyes
2.5
14.0
87
354
SPAT1262
SPAT
Handing over of treatment supplies
1.4
13.8
590
4305
H17.8
ICD-10 Finland
Other corneal scars and opacities
11.4
13.8
25
22
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
11.4
13.8
25
22
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
4.1
13.7
37
91
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
12.1
13.6
24
20
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.9
13.6
29
59
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
13.5
13
*
ZXD05
NOMESCO Finland
Urgent procedure
1.4
13.5
950
7540
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.5
13.5
45
129
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.9
13.4
167
896
A02BC02
ATC
pantoprazole; systemic
1.3
13.4
2214
19825
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
13.3
723
5502
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
4.1
13.3
36
89
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.7
13.2
24
42
S01AA01
ATC
chloramphenicol; ophthalmic
1.9
13.2
164
880
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
5.5
13.1
25
46
196
Kela drug reimbursment
Paricalcitol and cinacalcet
5.9
13.0
23
39
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.8
12.9
198
1133
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
19.1
12.9
19
10
A10AE06
ATC
insulin degludec; parenteral
2.3
12.7
98
439
Z71.8
ICD-10 Finland
Other specified counselling
1.3
12.7
919
7315
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
4.1
12.6
34
84
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
5.2
12.5
25
48
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.8
12.5
179
1005
CHC00
NOMESCO Finland
Iridotomy
130.5
12.4
13
*
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
13.2
12.4
21
16
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
3.0
12.3
52
173
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
5.4
12.3
24
45
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.3
12.2
91
402
M45
ICD-10 Finland
Ankylosing spondylitis
2.8
12.2
58
206
J01AA02
ATC
doxycycline; systemic
1.3
12.2
2434
22205
XCH00, ,
SPAT
18.1
12.0
18
10
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
3.3
12.0
44
134
H27.8
ICD-10 Finland
Other specified disorders of lens
5.7
11.9
22
39
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
3.4
11.9
42
125
A11CC03
ATC
alfacalcidol; systemic
2.2
11.9
93
420
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
4.7
11.9
27
58
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.7
11.8
238
1470
L04AD01
ATC
ciclosporin; systemic
3.1
11.8
47
151
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
5.9
11.8
21
36
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
11.8
632
4792
S01GX09
ATC
olopatadine; ophthalmic
2.4
11.6
77
323
3661A
ICD-9 Finland
Cataract, Senile cataract
2.3
11.6
82
354
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
12.6
11.6
20
16
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
12.6
11.6
20
16
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
23.0
11.6
16
7
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
3.3
11.5
42
128
165
Kela drug reimbursment
Preservative-free combination of bimatoprost and timolol
+∞
11.5
11
*
CHD60
NOMESCO Finland
Deep sclerectomy without implant
+∞
11.5
11
*
3659X
ICD-9 Finland
Glaucoma, Unspecified glaucoma
+∞
11.5
11
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
2.6
11.4
64
248
H33.5
ICD-10 Finland
Other retinal detachments
3.9
11.4
33
86
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
3.8
11.2
33
87
R42
ICD-10 Finland
Dizziness and giddiness
1.3
11.2
848
6778
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
25.1
11.1
15
6
J01FF01
ATC
clindamycin; systemic
1.3
11.1
776
6127
H46
ICD-10 Finland
Optic neuritis
5.3
11.1
22
42
H3600, E113,
ICD-10 Finland
2.7
11.0
57
212
AA1AD
NOMESCO Finland
CT of head and brain
1.3
11.0
1084
8979
H16.2
ICD-10 Finland
Keratoconjunctivitis
4.8
10.9
24
50
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
3.4
10.8
38
113
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
4.3
10.8
27
63
OAB50, ,
SPAT
1.6
10.7
238
1508
ZX198
NOMESCO Finland
Other local administration
3.0
10.7
47
160
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
21.5
10.7
15
7
J05AB11
ATC
valaciclovir; oral
1.5
10.7
408
2909
Z49.0
ICD-10 Finland
Preparatory care for dialysis
3.3
10.7
40
124
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
60.2
10.6
12
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
4.1
10.6
28
68
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
2.7
10.6
56
211
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
3.9
10.6
30
77
L17
ICPC
Foot/toe symptom/complaint
1.3
10.5
911
7407
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
10.5
582
4427
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
10.5
516
3848
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
10.5
1192
10044
H221, M084,
ICD-10 Finland
+∞
10.4
10
*
3651D
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA PIGMENTOSUM]
+∞
10.4
10
*
37598
ICD-8 Finland
Glaucoma, Aliud definitum
+∞
10.4
10
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
16.1
10.3
16
10
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
12.1
10.3
18
15
A28
ICPC
Limited function/disability NOS
1.3
10.3
834
6718
H44.0
ICD-10 Finland
Purulent endophthalmitis
8.8
10.3
21
24
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.3
10.3
37
112
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
9.6
10.2
20
21
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
3.8
10.2
30
79
J05AB01
ATC
aciclovir; systemic
1.4
10.2
632
4894
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
10.2
1290
11008
CJF20
NOMESCO Finland
Removal of artificial lens
13.1
10.1
17
13
H15.1
ICD-10 Finland
Episcleritis
3.3
10.1
37
113
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
2.1
10.1
99
490
H05BX01
ATC
cinacalcet; oral
4.0
10.0
28
71
S01FA06
ATC
tropicamide; ophthalmic
10.0
10.0
19
19
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.2
10.0
38
119
H35.29
ICD-10 Finland
Other proliferative retinopathy
40.2
10.0
12
*
H33.2
ICD-10 Finland
Serous retinal detachment
5.2
9.8
20
39
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
26.1
9.8
13
5
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.3
9.8
817
6603
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
8.7
9.8
20
23
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
8.7
9.8
20
23
C03CA01
ATC
furosemide; systemic
1.3
9.7
1444
12541
R03AC02
ATC
salbutamol; inhalant
1.3
9.7
1543
13505
N0830, E102,
ICD-10 Finland
55.1
9.6
11
*
S01AA12
ATC
tobramycin; ophthalmic
4.8
9.5
21
44
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
10.0
9.5
18
18
L01BA01
ATC
methotrexate; systemic
1.9
9.4
114
607
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
2.2
9.4
74
336
3718X
ICD-9 Finland
Corneal opacity and other disorders of cornea, Other corneal disorders
30.1
9.4
12
*
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
30.1
9.4
12
*
37511
ICD-8 Finland
Glaucoma, Chronicum irritativum sive congestivum
+∞
9.4
9
*
CHB50
NOMESCO Finland
Trabeculotomy
+∞
9.4
9
*
CHF12
NOMESCO Finland
Endoscopic laser coagulation of ciliary body
+∞
9.4
9
*
3702
FHL
Trabeculotomy
+∞
9.4
9
*
R4110
NOMESCO Finland
Physiotherapy
1.3
9.4
847
6913
C08CA13
ATC
lercanidipine; oral
1.4
9.4
530
4043
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
8.7
9.3
19
22
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.7
9.3
182
1119
R53
ICD-10 Finland
Malaise and fatigue
1.3
9.2
846
6913
F27
ICPC
Fear of eye disease
3.1
9.2
37
120
H02AB04
ATC
methylprednisolone; systemic
1.4
9.2
430
3177
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.1
9.1
84
407
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
4.8
9.1
20
42
L04AB06
ATC
golimumab; parenteral
4.6
9.1
21
46
CDC40
NOMESCO Finland
Evisceration of eye with insertion of prosthesis
36.8
9.0
11
*
CBH30
NOMESCO Finland
Tarsorraphy
36.8
9.0
11
*
A10AA03, ,
ATC
2.8
9.0
44
160
F01
ICPC
Eye pain
2.2
8.9
75
350
Z97.0
ICD-10 Finland
Presence of artificial eye
24.1
8.9
12
5
TCG30
NOMESCO Finland
Imaging of anterior and posterior part of cornea
12.5
8.9
15
12
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.6
8.8
184
1149
L28
ICPC
Limited function/disability (L)
1.3
8.6
776
6318
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.7
8.6
149
886
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
11.6
8.6
15
13
WX402
NOMESCO Finland
General anaesthesia
1.3
8.5
525
4054
C10AA01
ATC
simvastatin; oral
1.2
8.5
1610
14290
0147, ,
NOMESCO Finland
27.6
8.5
11
*
H16.3
ICD-10 Finland
Interstitial and deep keratitis
27.6
8.5
11
*
C10AA05
ATC
atorvastatin; oral
1.2
8.5
1428
12515
V03AE01
ATC
polystyrene sulfonate; oral
2.4
8.5
54
224
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.7
8.5
143
845
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.4
8.4
400
2964
N20.1
ICD-10 Finland
Calculus of ureter
1.9
8.4
102
546
3651E
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA INFANTILE SEU JUVENILE]
+∞
8.3
8
*
3650B
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AHDASKULMA)]
+∞
8.3
8
*
S01EXXX, ,
ATC
+∞
8.3
8
*
CHD30
NOMESCO Finland
Laser trabeculectomy
+∞
8.3
8
*
3652A
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[AKUUTTI AHDASKULMAGLAUKOOMA]
+∞
8.3
8
*
3651C
ICD-9 Finland
Glaucoma, Open-angle glaucoma[MATALAPAINEGLAUKOOMA]
+∞
8.3
8
*
H221, M083,
ICD-10 Finland
+∞
8.3
8
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
3.2
8.2
32
102
J01MA02
ATC
ciprofloxacin; systemic
1.2
8.2
1273
11045
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
8.2
668
5365
37403
ICD-8 Finland
Cataract, Complicata
14.5
8.2
13
9
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
4.5
8.1
19
42
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.8
8.1
113
632
S01GX08
ATC
ketotifen; ophthalmic
1.9
8.0
96
511
3604
FHL
Penetration of the cornea
22.1
8.0
11
5
H20
ICD-10 Finland
Iridocyclitis
6.3
8.0
20
32
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.1
8.0
21
51
H53.1
ICD-10 Finland
Subjective visual disturbances
1.6
8.0
191
1234
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
8.0
600
4766
N18.0
ICD-10 Finland
End-stage renal disease
2.6
7.9
43
165
F94
ICPC
Blindness
13.0
7.9
13
10
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
7.9
1796
16203
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
7.8
57
251
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
7.8
881
7365
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.5
7.8
219
1467
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
3.7
7.7
24
66
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
45.1
7.7
9
*
4AA12, ,
NOMESCO Finland
15.0
7.7
12
8
T90
ICPC
Diabetes non-insulin dependent
1.3
7.7
776
6400
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.5
7.7
236
1611
H02AB07
ATC
prednisone; oral
1.4
7.7
433
3297
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
5.9
7.7
20
34
CGF10
NOMESCO Finland
Suture of laceration of cornea
7.4
7.7
17
23
H54.7
ICD-10 Finland
Unspecified visual loss
3.4
7.6
27
81
Z2446
NOMESCO Finland
Social worker
1.6
7.6
179
1151
S18
ICPC
Laceration/cut
1.2
7.6
1425
12580
3643
FHL
Vitrectomy through pars Plana
8.0
7.6
16
20
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
11.9
7.6
13
11
E10.01
ICD-10 Finland
Insulin-dependent diabetes diabetic coma with hyperglycemia
25.1
7.6
10
*
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
10.0
7.5
14
14
SPAT1325
SPAT
Vaccination
1.2
7.5
1115
9609
H52.2
ICD-10 Finland
Astigmatism
2.5
7.4
44
177
3656C
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA NEOVASCULARE]
+∞
7.3
7
*
CGG20
NOMESCO Finland
Epikeratofakia or keratofakia
+∞
7.3
7
*
H3603, H405,
ICD-10 Finland
+∞
7.3
7
*
CWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in eye and adjacent structures
+∞
7.3
7
*
H40.2
ICD-10 Finland
Primary angle-closure glaucoma
+∞
7.3
7
*
S01EB03
ATC
ecothiopate; ophthalmic
+∞
7.3
7
*
CHD20
NOMESCO Finland
Posterior sclerotomy
+∞
7.3
7
*
H40.21
ICD-10 Finland
Intermittent glaucoma with closed ventricular angle
+∞
7.3
7
*
36401
ICD-8 Finland
Iritis, Iridocyclitis glaucomatosa. Syndroma Posner-Schlossman, heterochromia iridis
+∞
7.3
7
*
L04AA17
ATC
[U] adalimumab
6.8
7.3
17
25
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
6.8
7.3
17
25
H3602, E103,
ICD-10 Finland
9.4
7.3
14
15
S01GX05
ATC
lodoxamide; ophthalmic
2.6
7.3
41
161
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
6.2
7.2
18
29
H16.1
ICD-10 Finland
Other superficial keratitis without conjunctivitis
5.8
7.2
19
33
Z3226
NOMESCO Finland
Physiotherapist
1.3
7.2
542
4302
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.2
752
6223
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
2.5
7.2
43
174
A02BC05
ATC
esomeprazole; systemic
1.2
7.1
1168
10153
H30.8
ICD-10 Finland
Other chorioretinal inflammations
30.1
7.1
9
*
H3601, E107,
ICD-10 Finland
30.1
7.1
9
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.6
7.1
153
964
JN3AD
NOMESCO Finland
Abdominal CT examination
1.4
7.1
379
2858
S01FB01
ATC
phenylephrine; ophthalmic
20.1
7.1
10
5
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
20.1
7.1
10
5
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
6.6
7.1
17
26
H16.8
ICD-10 Finland
Other keratitis
7.9
7.1
15
19
J01FA10
ATC
azithromycin; systemic
1.2
7.1
1367
12083
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
6.0
7.1
18
30
L88
ICPC
Rheumatoid/seropositive arthritis
1.7
7.0
111
646
CJD20
NOMESCO Finland
Extracapsular cataract extraction with implantation of artificial lens in posterior chamber
6.3
6.9
17
27
H10.4
ICD-10 Finland
Chronic conjunctivitis
3.0
6.9
29
97
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
1.9
6.9
86
465
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
7.5
6.9
15
20
H22.0*B00.5
ICD-10 Finland
Herpesviral iridocyclitis
13.8
6.9
11
8
S97
ICPC
Chronic ulcer skin
1.5
6.9
237
1657
D07AC01
ATC
betamethasone; topical
1.2
6.9
1031
8877
H35.8
ICD-10 Finland
Other specified retinal disorders
3.3
6.8
24
72
H15.0
ICD-10 Finland
Scleritis
6.7
6.8
16
24
R5599
NOMESCO Finland
Other rehabilitation service
1.9
6.8
84
453
H26.1
ICD-10 Finland
Traumatic cataract
4.3
6.7
17
40
137
Kela drug reimbursment
Uraemia requiring dialysis
3.1
6.7
27
88
R06AE07
ATC
cetirizine; oral
1.2
6.7
1132
9857
H35.9
ICD-10 Finland
Retinal disorder, unspecified
3.5
6.7
22
63
J45
ICD-10 Finland
Asthma
1.4
6.7
260
1859
B05DA
ATC
Isotonic solutions
3.3
6.7
24
73
CKD45
NOMESCO Finland
Endocryotherapy of retina
22.6
6.7
9
*
S01GX06
ATC
emedastine; ophthalmic
2.7
6.7
34
127
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
6.4
6.6
16
25
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.6
991
8523
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
12.3
6.6
11
9
N03AX16
ATC
[U] pregabalin
1.3
6.6
659
5421
I79.2*E10.5
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
8.7
6.5
13
15
C09CA01
ATC
losartan; oral
1.2
6.5
845
7155
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
6.8
6.5
15
22
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
2.8
6.5
31
112
N03AX12
ATC
[U] gabapentin; oral
1.3
6.4
446
3497
J02AC01
ATC
fluconazole; systemic
1.2
6.4
927
7936
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.2
6.4
51
234
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
6.4
528
4236
7143D
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[OLIGARTHRITIS JUVENILIS]
70.0
6.4
7
*
CHB65
NOMESCO Finland
Posterior synechiolysis
70.0
6.4
7
*
CKB00
NOMESCO Finland
Puncture and evacuation of suprachorioidal fluid
70.0
6.4
7
*
-1, ,
SPAT
1.8
6.4
90
506
R01AD09
ATC
mometasone; nasal
1.2
6.4
1058
9186
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.3
6.4
406
3145
H3603, E106,
ICD-10 Finland
14.3
6.4
10
7
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.6
6.4
146
936
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
6.4
478
3791
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
8.2
6.3
13
16
R30.0
ICD-10 Finland
Dysuria
1.7
6.3
113
681
NGQ20
NOMESCO Finland
Amputation of lower leg
2.9
6.3
28
97
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
11.0
6.3
11
10
3640A
ICD-9 Finland
Disorders of iris and ciliary body, Acute and subacute iridocyclitis
11.0
6.3
11
10
CHC10
NOMESCO Finland
Peripheral iridectomy
18.0
6.3
9
5
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
18.0
6.3
9
5
H3603, E117,
ICD-10 Finland
18.0
6.3
9
5
B03XA02
ATC
darbepoetin alfa; parenteral
1.9
6.3
73
387
S01EA01
ATC
epinephrine; ophthalmic
+∞
6.3
6
*
CHC04
NOMESCO Finland
Ventricular angle laser gonoplasty
+∞
6.3
6
*
S01EB51
ATC
pilocarpine, combinations; ophthalmic
+∞
6.3
6
*
JL9AE
NOMESCO Finland
Ultrasound examination of pancreas transplant
+∞
6.3
6
*
A12AA04
ATC
calcium carbonate; oral
2.2
6.2
51
237
C09CA06
ATC
candesartan; oral
1.3
6.2
668
5534
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.6
6.2
135
854
WX400
NOMESCO Finland
Inhalation anesthesy
1.8
6.2
89
503
R55
ICD-10 Finland
Syncope and collapse
1.3
6.2
403
3134
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
1.7
6.2
101
594
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.7
6.2
112
678
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
6.2
429
3367
A10AD04
ATC
insulin lispro; parenteral
3.5
6.2
20
57
CKC30
NOMESCO Finland
Cryopexy of detached retina
3.2
6.1
23
72
1LA05, ,
NOMESCO Finland
3.2
6.1
23
72
N18.8
ICD-10 Finland
Other chronic renal failure
1.8
6.1
89
506
R01AD08
ATC
fluticasone; nasal
1.3
6.1
651
5394
SPAT1263
SPAT
Sampling
1.2
6.1
1212
10706
H44.1
ICD-10 Finland
Other endophthalmitis
8.6
6.0
12
14
CJW99
NOMESCO Finland
Other operation on lens
8.6
6.0
12
14
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
6.0
957
8266
H18.3
ICD-10 Finland
Changes in corneal membranes
10.0
6.0
11
11
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2431
20698
1.58
32.06
30.0
25.1
14.00
13.97
%
0.57
2392
20398
572
3617
1.70
26.75
2.2
1.8
—
—
—
0
0
1676
13493
1.47
26.37
7.9
6.3
0.65
0.65
%
0.09
1577
12502
1671
13497
1.46
25.53
7.8
6.2
2.91
2.79
%
1.48
1571
12518
2337
20150
1.49
25.33
6.0
5.3
1.35
1.98
—
9
33
1671
13531
1.45
24.99
7.9
6.3
9.13
9.13
%
0.02
1572
12535
2995
27320
1.69
24.89
29.7
25.0
4.00
4.00
mmol/l
0.10
2925
26661
1689
13716
1.45
24.81
8.0
6.2
25.24
25.78
%
1.16
1604
12871
2992
27292
1.69
24.78
29.2
24.8
139.34
139.51
mmol/l
2.49
2926
26673
2537
22299
1.51
24.54
9.0
8.3
82.70
82.83
u/l
0.04
2404
20951
2914
26441
1.63
24.18
24.1
20.2
26.33
27.57
mg/l
1.21
2535
22592
1650
13438
1.43
23.31
7.9
6.1
59.50
58.91
%
1.15
1580
12702
1757
14498
1.43
22.95
7.6
5.9
0.04
0.04
e9/l
0.50
1497
12141
1750
14446
1.43
22.71
7.6
5.9
0.63
0.62
e9/l
1.49
1492
12075
3016
27701
1.67
22.69
31.6
27.1
86.79
82.99
umol/l
3.89
2966
27222
1782
14762
1.42
22.65
7.8
6.0
1.82
1.85
e9/l
0.20
1546
12672
1790
14899
1.42
21.80
7.7
6.1
0.20
0.19
e9/l
1.05
1540
12680
1776
14854
1.40
20.51
2.4
2.3
95.85
94.53
pmol/l
0.51
881
7727
1638
13519
1.40
20.42
2.8
2.4
79.45
80.16
nmol/l
0.44
1437
11801
2956
27168
1.59
20.39
14.9
13.0
23.55
23.99
u/l
0.49
2857
26110
3022
27924
1.63
20.34
35.9
30.4
245.05
243.26
e9/l
0.71
2936
27185
3022
27926
1.63
20.31
35.8
30.3
92.18
91.73
fl
5.77
2971
27458
1845
15547
1.40
20.30
5.0
4.6
3.27
2.42
estimate
0.09
486
3428
3022
27928
1.63
20.28
35.7
30.3
30.43
30.36
pg
1.50
2971
27460
3022
27929
1.63
20.26
35.8
30.4
4.30
4.34
e12/l
4.94
2911
27073
3022
27929
1.63
20.26
36.5
30.8
38.74
39.23
%
1.81
2971
27447
1190
9301
1.42
20.26
4.2
3.6
0.37
0.53
e6/l
2.55
910
6998
3022
27933
1.62
20.20
36.2
30.6
129.48
130.69
g/l
4.27
2972
27487
3022
27934
1.62
20.19
35.8
30.4
7.05
6.97
e9/l
0.75
2913
27073
66
186
3.60
20.11
1.2
1.1
—
—
—
0
0
2298
20180
1.41
19.36
6.5
5.8
521.86
3254.64
e6/l
3.88
35
340
894
6685
1.45
19.14
3.4
3.2
504.06
523.43
mosm/kgh2o
2.22
793
5840
1124
8771
1.42
19.03
4.2
3.5
0.00
0.00
estimate
—
9
53
1971
16896
1.38
18.97
9.0
7.1
1.21
1.21
mmol/l
0.08
1677
14471
1278
10201
1.40
18.96
5.8
4.1
7.39
7.40
ph
4.13
940
7359
29
43
6.79
18.68
5.7
3.9
—
—
—
0
0
1488
12220
1.38
18.45
16.0
12.6
0.00
0.00
e9/l
0.97
1231
9768
1450
11858
1.38
18.45
5.4
4.3
123.19
136.13
e6/l
0.21
1062
8567
1746
14727
1.37
18.27
5.5
4.9
34.37
34.53
g/l
0.56
1622
13632
2354
20849
1.40
18.20
5.1
4.5
15.54
15.02
mm/h
0.77
2182
19196
1841
15666
1.37
18.20
5.1
4.6
0.02
0.11
estimate
0.47
445
3218
1547
12805
1.37
18.18
3.6
3.2
147.82
142.99
ug/l
0.28
1395
11649
1916
16436
1.37
17.85
9.9
9.1
4.39
4.33
e9/l
0.49
1638
14038
25
33
7.62
17.82
2.4
2.4
8.45
8.37
mg/l
0.02
19
28
2692
24458
1.45
17.67
5.9
5.6
2.05
2.04
mu/l
0.14
2425
22075
1803
15342
1.36
17.56
5.0
4.6
0.00
0.00
estimate
0.80
462
3278
1777
15108
1.36
17.29
8.1
6.3
1.22
1.21
mmol/l
2.22
1636
13802
1170
9313
1.39
17.22
2.6
2.5
3.03
3.06
mg/l
0.14
1013
7967
716
5231
1.46
17.03
3.5
2.6
20.53
20.94
%
0.40
663
4813
35
69
5.11
16.93
51.1
34.0
7.38
6.76
ug/l
1.07
35
62
798
5974
1.44
16.62
3.4
2.6
11.13
11.72
umol/l
1.80
736
5484
752
5614
1.43
15.80
3.4
2.6
2.19
2.26
g/l
3.02
688
5124
2707
24770
1.42
15.79
8.5
7.3
42.17
40.42
mmol/mol
13.88
2447
22625
1833
15857
1.33
14.91
20.1
19.9
1.38
1.37
inr
0.21
1567
13407
1310
10793
1.34
14.91
4.4
3.7
129.35
71.85
e6/l
0.54
1024
8359
1251
10238
1.35
14.88
1.8
1.8
21.38
20.07
nmol/l
2.13
1061
8549
2067
18203
1.33
14.81
6.8
5.0
7.10
6.87
mmol/l
4.22
1973
17376
99
419
2.40
14.59
1.7
1.3
—
—
—
0
0
723
5431
1.42
14.53
3.8
3.4
1.94
2.74
e6/l
2.88
371
2758
33
72
4.62
14.22
1.8
1.5
—
—
—
0
0
1243
10229
1.33
14.03
5.0
4.4
—
—
—
0
0
1864
16256
1.32
13.87
5.9
6.4
12.45
12.37
umol/l
0.06
1767
15417
120
569
2.15
13.54
1.1
1.1
—
—
—
0
0
97
421
2.34
13.54
1.7
1.3
—
19.96
—
0
9
613
4523
1.43
13.51
8.6
5.2
1.08
1.04
mmol/l
2.74
565
4144
2755
25485
1.39
13.44
6.5
6.2
2.45
2.52
mmol/l
4.46
2471
23044
413
2827
1.52
13.31
5.1
3.5
105.23
94.86
ng/l
1.22
346
2344
1467
12432
1.31
13.21
4.2
4.0
6.28
6.31
ph
0.36
741
6656
2733
25288
1.38
12.99
5.9
5.7
6.30
6.08
mmol/l
9.13
2414
22526
614
4562
1.42
12.97
2.4
2.4
1.81
1.81
%
0.07
540
3985
1259
10469
1.32
12.93
5.1
4.1
15.99
8.92
mg/mmol
2.69
811
6508
2278
20542
1.32
12.73
4.6
4.5
15.15
15.15
pmol/l
0.01
2023
18369
1226
10199
1.31
12.42
4.2
3.4
76.40
47.96
mg/l
2.49
806
6571
1371
11597
1.30
12.21
4.1
3.8
—
—
—
0
0
159
868
1.87
12.12
4.0
2.5
1.81
1.73
mg/l
0.47
146
751
1245
10420
1.30
11.93
4.1
3.3
6.50
6.82
mmol/l
2.02
1032
8613
942
7587
1.33
11.90
3.3
2.9
5.57
5.57
e6/l
0.00
856
6911
2679
24832
1.34
11.66
5.6
5.3
4.35
4.44
mmol/l
4.11
2411
22500
385
2677
1.49
11.46
2.3
2.1
400.50
386.68
nmol/l
0.61
348
2438
2653
24594
1.33
11.27
5.5
5.2
1.45
1.46
mmol/l
1.09
2364
22120
1049
8638
1.31
11.18
6.8
6.5
—
—
—
0
0
22
42
5.27
11.05
1.0
1.0
—
—
—
0
0
747
5871
1.35
11.01
3.7
3.2
1.12
1.29
e6/l
0.64
398
3206
953
7771
1.31
10.85
4.3
4.1
0.77
0.45
estimate
0.18
371
2559
21
40
5.28
10.58
1.1
1.1
—
—
—
0
0
942
7711
1.30
10.34
4.8
4.1
85.13
84.18
%
0.56
924
7539
81
368
2.23
10.25
1.9
1.3
146.56
158.31
au/ml
0.39
25
107
459
3374
1.42
10.15
1.3
1.3
466.93
548.84
titre
0.56
101
792
1057
8804
1.29
10.12
3.2
3.1
28.84
35.37
u/l
5.63
995
8243
362
2557
1.46
9.92
4.4
4.5
0.41
0.15
%
0.39
99
705
957
7902
1.29
9.73
3.8
3.5
0.15
0.08
0.46
46
310
1470
12790
1.26
9.72
5.0
4.6
44.31
116.15
ng/l
1.38
1158
10098
31
88
3.55
9.49
1.2
1.2
—
—
—
0
0
48
178
2.72
9.40
1.2
1.2
—
—
—
0
0
49
185
2.67
9.28
2.3
2.4
24.83
38.42
iu/ml
—
9
31
1193
10174
1.26
9.23
2.2
1.9
1.30
1.30
mmol/l
0.06
953
8343
360
2582
1.44
9.09
4.2
4.3
0.06
0.10
%
0.70
95
769
357
2559
1.44
9.05
4.1
4.1
0.53
0.73
%
1.02
107
834
323
2283
1.46
8.82
5.4
4.7
—
—
—
0
0
580
4529
1.34
8.74
2.6
2.0
—
—
—
0
0
684
5485
1.31
8.53
3.0
2.9
0.82
0.81
mmol/l
0.39
630
5063
1353
11783
1.24
8.52
3.4
3.4
2083.41
1925.88
ng/l
0.48
1180
10322
371
2708
1.41
8.50
4.2
4.2
0.70
0.95
%
1.42
106
895
467
3551
1.36
8.37
2.6
2.5
70.74
68.20
e9/l
0.84
324
2601
222
1484
1.53
7.98
1.5
1.4
—
—
—
0
0
843
7006
1.27
7.87
1.9
1.8
1131.80
1158.03
nmol/l
0.35
628
5187
397
2971
1.38
7.84
3.3
2.4
38.93
54.20
u/l
0.43
332
2468
424
3210
1.37
7.79
2.5
2.6
66.37
65.78
g/l
0.79
372
2858
433
3313
1.35
7.43
1.5
1.5
—
—
—
0
0
640
5174
1.29
7.41
2.1
2.0
30.23
29.87
s
0.67
619
4998
1265
11058
1.23
7.39
2.3
2.3
—
—
—
0
0
157
989
1.62
7.32
3.8
3.7
2.11
2.16
index
0.03
83
507
2517
23596
1.24
7.29
4.6
4.4
1.27
1.27
mmol/l
0.08
2213
20935
1292
11340
1.22
7.21
5.2
4.7
1.36
0.46
estimate
0.30
376
2685
17
39
4.38
6.95
1.1
1.0
—
—
—
0
0
1021
8773
1.23
6.94
5.2
4.7
0.00
0.00
estimate
1.34
406
2945
419
3223
1.34
6.93
11.0
6.1
12.30
11.38
mmol/l
1.39
399
3043
19
35
5.45
6.90
2.8
3.0
17.68
7.60
mg/l
—
5
29
1180
10298
1.22
6.89
2.2
2.2
165.77
216.17
u/l
2.75
1107
9667
1295
11426
1.21
6.73
3.5
3.4
2.35
2.36
mmol/l
1.12
1171
10191
116
692
1.70
6.70
5.3
4.6
2.55
2.86
mmol/l
0.62
82
484
206
1410
1.49
6.66
2.3
2.4
11.37
10.29
g/l
1.64
175
1215
234
1646
1.45
6.58
2.5
2.5
25.07
21.75
au/ml
0.17
16
127
27
91
2.98
6.37
2.6
2.3
0.62
0.61
mmol/l
0.46
27
91
525
4216
1.29
6.35
6.8
6.4
7.41
7.42
ph
0.54
284
2366
871
7421
1.23
6.32
4.9
4.3
0.12
0.11
0.02
17
119
215
1503
1.46
6.26
2.3
2.5
2.97
2.98
g/l
0.06
186
1322
227
1608
1.44
6.17
2.2
2.4
3.95
3.72
g/l
0.89
198
1430
227
1610
1.44
6.13
2.2
2.4
4.16
4.22
g/l
0.52
198
1432
840
7154
1.23
6.09
1.8
1.8
39344719.06
10968410.14
pmol/l
0.65
671
5744
227
1612
1.44
6.09
2.2
2.4
7.67
7.52
g/l
0.62
198
1431
124
773
1.63
6.09
4.4
3.9
—
—
—
0
0
267
1955
1.40
6.03
8.4
8.4
15.59
15.61
%
0.04
254
1893
213
1499
1.45
6.00
1.3
1.3
73.49
57.79
au/ml
—
9
101
140
903
1.57
5.97
2.2
2.2
124.73
125.75
g/l
0.17
109
697
521
4220
1.28
5.87
6.8
6.4
11.74
11.86
kpa
0.21
493
4032
793
6737
1.23
5.86
4.8
4.5
286.43
450.93
ng/l
0.55
700
5876
521
4221
1.28
5.85
6.8
6.4
5.03
5.10
kpa
0.84
492
4035
146
959
1.55
5.76
1.3
1.5
258.20
273.24
ug/g
0.42
94
577
1106
9723
1.20
5.75
3.6
2.6
63.32
68.93
u/l
0.25
1014
8921
74
406
1.84
5.74
2.0
1.8
89.36
89.27
%
0.05
74
401
516
4188
1.27
5.71
6.9
6.3
0.58
1.07
mmol/l
1.90
413
3417
468
3754
1.29
5.69
7.1
6.5
95.27
95.17
%
0.12
446
3619
622
5165
1.25
5.66
3.8
3.5
0.80
0.85
ug/l
0.53
462
3654
896
7732
1.21
5.65
2.9
2.9
357.34
358.60
umol/l
0.12
742
6575
97
583
1.68
5.52
2.2
2.0
0.97
0.88
%
0.84
68
404
744
6319
1.23
5.48
1.6
1.8
1.53
1.56
mg/l
0.06
591
4962
71
391
1.83
5.46
2.4
2.2
1.39
1.15
g/24h
0.31
45
224
1761
16179
1.18
5.41
3.3
3.3
49.70
54.62
u/l
1.62
1609
14771
193
1364
1.44
5.35
2.9
3.2
39.17
64.50
mg/l
1.32
160
1174
96
583
1.67
5.27
4.2
3.1
57.70
59.23
%
0.44
96
583
193
1368
1.43
5.27
2.9
3.2
50.51
97.02
mg/l
0.62
160
1174
178
1246
1.45
5.20
3.0
3.0
2.30
4.38
ratio
1.23
103
763
832
7186
1.21
5.13
3.1
3.1
2.47
2.47
mmol/l
0.39
724
6392
68
378
1.81
5.10
1.4
1.2
326.11
293.63
u/ml
0.37
46
212
16
36
4.46
5.04
9.7
16.0
5.01
5.22
mmol/l
0.09
16
36
22
76
2.91
5.03
28.9
27.9
108.12
114.21
ug/l
0.19
17
61
348
2734
1.30
4.96
5.9
3.7
1.23
1.23
mmol/l
0.26
301
2322
425
3427
1.27
4.95
7.7
7.0
118.00
118.86
g/l
0.40
412
3357
119
775
1.55
4.93
1.3
1.3
62.02
60.74
mmol/l
0.13
97
610
1010
8907
1.19
4.93
6.3
6.1
3.86
4.46
ug/l
0.28
891
7901
376
2990
1.29
4.89
2.1
2.0
127.05
159.44
ug/g
1.44
293
2331
655
5553
1.22
4.86
5.4
4.8
—
—
—
0
0
294
2268
1.32
4.79
2.2
1.5
—
—
—
0
0
280
2150
1.33
4.71
8.4
7.6
23.90
24.37
mmol/l
1.45
271
2079
386
3100
1.28
4.65
10.6
7.0
—
—
—
0
0
339
2697
1.28
4.41
2.1
1.5
—
—
—
0
0
462
3821
1.24
4.33
5.5
3.4
5.85
5.83
kpa
0.14
444
3724
425
3483
1.25
4.32
2.8
2.5
11.64
9.47
umol/l
0.56
359
3034
648
5551
1.21
4.29
1.3
1.3
1.23
1.58
u/ml
0.46
168
1356
420
3447
1.25
4.22
3.5
3.2
4.40
5.00
e9/l
1.60
354
2852
398
3248
1.25
4.20
8.0
6.0
1.33
1.39
mmol/l
0.48
392
3178
370
3002
1.26
4.11
2.2
1.6
—
—
—
0
0
50
272
1.85
4.08
1.2
1.3
—
—
—
0
0
448
3718
1.24
4.06
5.8
3.4
1.18
1.93
mmol/l
3.91
384
3218
187
1384
1.37
4.04
1.4
1.3
—
—
—
0
0
84
531
1.60
4.02
1.4
1.2
—
—
—
0
0
392
3211
1.25
4.01
4.4
2.9
4.53
4.38
kpa
0.70
376
3122
47
253
1.87
3.98
1.2
1.5
—
1573.33
—
0
9
139
981
1.43
3.96
1.9
1.9
22.06
21.47
s
0.26
124
900
196
1473
1.35
3.86
2.2
2.1
0.00
0.62
estimate
0.50
59
404
71
446
1.60
3.53
1.4
1.2
—
—
—
0
0
294
2377
1.26
3.39
3.9
3.7
5.18
5.16
kpa
0.12
272
2232
80
523
1.54
3.37
8.3
1.4
0.80
0.83
nmol/l
0.15
63
426
455
3862
1.20
3.31
5.4
3.4
7.36
7.38
ph
4.18
293
2324
463
3939
1.20
3.29
1.2
1.3
—
—
—
0
0
150
1111
1.37
3.29
1.5
1.6
—
—
—
0
0
167
1260
1.34
3.25
2.6
3.0
24.60
24.96
mmol/l
0.50
162
1237
198
1532
1.31
3.24
3.3
3.3
4.30
4.38
pmol/l
0.33
173
1325
285
2311
1.25
3.22
3.9
3.7
7.40
7.42
ph
3.57
239
1924
562
4880
1.18
3.17
1.6
1.5
2.46
2.66
g/l
1.30
324
2770
60
373
1.62
3.15
1.5
1.3
272.86
274.42
mosm/kgh2o
0.24
49
257
21
92
2.29
3.10
1.0
1.2
—
—
—
0
0
23
105
2.20
3.09
1.3
1.2
0.61
0.50
ratio
0.39
12
61
367
3074
1.22
3.07
1.4
1.3
—
—
—
0
0
1468
13666
1.13
3.07
3.1
2.9
—
—
estimate
—
0
0
520
4500
1.18
3.05
1.3
1.3
45.19
37.16
iu/ml
0.37
148
1362
34
181
1.89
3.05
1.8
1.9
39.69
38.50
%
0.19
34
176
30
153
1.97
3.04
1.2
1.1
51.77
40.99
mg/l
0.53
25
126
59
370
1.60
3.00
1.4
1.2
298.61
284.37
pmol/l
0.12
49
304
355
2978
1.21
2.93
2.3
2.2
0.00
0.01
estimate
1.05
74
537
7
13
5.39
2.87
3.6
4.6
—
—
—
0
0
227
1822
1.26
2.83
2.6
2.5
—
—
—
0
0
105
756
1.40
2.78
1.5
1.5
0.24
0.23
g/l
0.40
100
719
21
98
2.15
2.70
1.2
1.3
136.76
161.93
mmol/24h
0.72
21
98
233
1892
1.25
2.64
1.7
1.7
1.55
1.55
g/l
0.02
200
1629
38
220
1.74
2.64
1.4
1.3
—
—
—
0
0
283
2347
1.22
2.64
4.5
2.9
123.58
126.81
g/l
1.55
268
2283
59
383
1.55
2.64
1.4
1.5
0.67
0.85
g/l
0.62
45
301
59
384
1.55
2.61
3.6
3.5
14.21
11.44
index
0.91
33
200
106
774
1.38
2.60
1.5
1.5
1.18
1.18
g/l
0.01
101
735
26
134
1.95
2.60
1.9
1.7
13.82
17.33
nmol/l
1.80
26
119
85
599
1.43
2.56
1.4
1.5
29.19
30.65
g/l
0.42
76
545
2153
20622
1.12
2.53
31.9
26.7
329.70
330.44
g/l
3.25
2132
20439
824
7477
1.13
2.53
3.7
3.6
—
—
—
0
0
29
157
1.85
2.52
2.6
2.2
41.20
87.66
ug/min
—
10
35
42
254
1.66
2.51
1.3
1.2
—
—
—
0
0
93
669
1.40
2.51
2.0
1.9
2.70
12.83
iu/l
0.57
31
255
16
69
2.32
2.48
1.1
1.5
—
—
—
0
0
58
382
1.53
2.45
1.2
1.2
222.51
233.44
miu/ml
0.04
11
138
42
256
1.65
2.45
1.1
1.1
31.10
34.82
mmol/l
0.97
37
209
113
844
1.35
2.43
1.6
1.5
—
—
—
0
0
34
196
1.74
2.42
1.9
1.6
1869.53
1747.01
ml
0.37
34
188
191
1533
1.26
2.42
4.3
4.7
0.92
0.85
%
1.42
176
1459
60
400
1.51
2.41
1.6
1.3
48.90
69.17
mu/l
0.51
51
344
60
400
1.51
2.41
1.3
1.3
0.57
5.17
nmol/l
0.51
55
379
38
227
1.68
2.39
1.3
1.3
2.86
2.83
g/l
0.04
26
171
38
227
1.68
2.39
1.3
1.3
0.35
0.45
g/l
1.10
26
170
38
227
1.68
2.39
1.3
1.3
6.45
6.87
g/l
0.35
26
170
50
321
1.57
2.38
1.4
1.4
21.29
30.98
ng/l
1.51
50
321
73
508
1.45
2.38
1.7
1.7
4.78
4.48
mmol/24h
0.38
66
425
1093
10119
1.12
2.37
2.7
2.6
—
—
—
0
0
27
146
1.86
2.37
2.3
1.9
101.15
137.83
e6/l
0.54
27
136
60
878
0.68
2.36
19.1
12.8
—
—
—
0
0
18
84
2.15
2.34
1.1
1.5
13.22
23.31
%
1.54
12
71
95
697
1.37
2.31
5.3
6.2
11.65
11.11
mmol/l
0.84
84
629
95
697
1.37
2.31
5.3
6.3
104.71
104.84
mmol/l
0.09
84
630
173
1383
1.26
2.29
1.2
1.3
199.28
229.75
u/ml
0.13
159
1272
52
341
1.53
2.27
1.5
1.5
51.08
61.13
%
0.87
26
222
134
1038
1.30
2.27
1.7
1.7
5.59
6.41
iu/ml
0.27
32
244
61
415
1.48
2.24
2.3
1.7
393.40
289.04
mu/l
0.93
55
378
26
142
1.84
2.23
2.5
1.8
394.67
533.86
e6/l
0.86
21
115
107
807
1.34
2.19
3.3
2.9
89.17
88.87
%
0.18
101
785
119
916
1.31
2.13
1.5
1.6
21.29
25.75
u/ml
0.21
19
148
443
3910
1.15
2.06
1.4
1.4
—
—
—
0
0
71
508
1.41
2.03
1.2
1.3
—
—
—
0
0
162
1306
1.25
2.03
2.1
2.1
588.20
659.90
ug/l
0.09
151
1234
47
311
1.52
2.00
1.1
1.4
—
—
—
0
0
64
451
1.43
2.00
1.4
1.6
—
—
—
0
0
29
170
1.71
2.00
1.6
1.7
—
—
—
0
0
19
97
1.96
2.00
1.0
1.0
2049.95
1538.20
miu/ml
1.20
19
97
38
241
1.58
1.95
2.5
3.1
62.14
20.94
mg/l
0.47
27
184
128
1009
1.28
1.94
4.9
5.5
1.25
1.33
mmol/l
0.60
110
903
168
1371
1.24
1.90
1.2
1.3
—
—
—
0
0
37
236
1.57
1.87
2.7
2.2
607.35
643.95
ml
0.26
23
139
8
28
2.86
1.86
1.1
1.1
—
—
—
0
0
15
72
2.09
1.86
1.8
1.3
—
—
—
0
0
473
4226
1.14
1.85
1.3
1.3
26.38
13.71
u/ml
1.64
150
1439
136
1089
1.26
1.83
1.2
1.3
—
—
—
0
0
200
1670
1.21
1.82
4.3
4.5
1.53
1.55
%
0.12
186
1592
50
343
1.46
1.82
1.4
1.3
—
—
nmol/l
—
0
0
44
295
1.50
1.79
1.3
1.2
1.86
5.93
u/ml
2.09
14
146
20
350
0.57
1.77
2.0
2.0
—
—
—
0
0
20
349
0.57
1.75
2.0
1.9
—
—
—
0
0
55
388
1.42
1.74
1.1
1.1
—
—
—
0
0
65
474
1.38
1.71
6.6
6.1
12.18
12.78
mg/l
0.44
59
436
188
1572
1.21
1.71
1.7
1.9
2.45
2.27
ug/l
0.07
154
1351
46
315
1.47
1.71
1.3
1.3
18.07
12.47
u/l
0.59
41
286
240
2055
1.18
1.68
3.0
2.8
10.80
10.74
g/l
0.07
220
1875
19
329
0.58
1.64
1.4
1.2
—
—
—
0
0
87
670
1.31
1.62
1.1
1.2
—
—
—
0
0
119
954
1.26
1.62
1.2
1.2
0.29
0.70
u/ml
0.81
15
73
35
229
1.53
1.62
1.3
1.3
—
—
—
0
0
21
352
0.59
1.61
2.0
2.0
—
—
—
0
0
50
354
1.42
1.58
1.3
1.3
0.19
0.19
nmol/l
0.07
42
287
21
350
0.60
1.58
2.0
2.0
—
—
—
0
0
35
231
1.52
1.57
2.8
2.9
18.11
31.29
mg/l
3.25
28
182
194
1643
1.19
1.56
2.2
1.8
1.40
1.41
g/l
0.01
174
1480
47
331
1.43
1.54
1.2
1.2
—
—
—
0
0
74
562
1.32
1.54
1.3
1.4
164.53
599.86
e6/l
1.19
51
445
40
273
1.47
1.53
1.8
2.0
349.91
3601.21
u/l
—
7
108
73
555
1.32
1.51
1.3
1.3
60.00
38.53
e6/l
0.14
45
415
94
740
1.28
1.50
2.9
2.3
195.72
76.45
ug/min
0.71
51
423
60
443
1.36
1.50
1.4
1.4
31.69
30.02
iu/l
0.14
49
375
9
37
2.44
1.47
1.8
1.6
55.89
46.73
umol/l
—
9
37
36
243
1.49
1.47
1.3
1.3
—
—
—
0
0
364
3255
1.13
1.44
3.4
3.3
274.72
253.10
ng/l
0.37
329
2990
24
148
1.63
1.44
1.2
1.6
66.19
68.36
%
0.13
16
120
20
328
0.61
1.43
2.0
2.1
—
—
—
0
0
13
66
1.97
1.43
6.4
5.8
8.78
8.52
mmol/l
0.14
13
66
26
164
1.59
1.43
2.7
2.0
488.33
499.71
min
0.23
18
109
355
3173
1.13
1.42
1.9
2.1
0.20
0.20
g/l
0.09
331
2923
67
873
0.76
1.41
1.3
1.4
—
—
—
0
0
825
7717
1.09
1.39
2.7
2.5
—
—
—
0
0
7
29
2.42
1.39
1.1
1.2
—
—
—
0
0
45
322
1.40
1.38
1.1
1.1
15.83
17.31
au/ml
—
6
49
61
459
1.33
1.37
24.0
5.8
7.94
7.39
mmol/l
0.50
53
388
25
158
1.59
1.37
2.1
1.9
17.72
17.70
%
0.00
25
150
300
2660
1.14
1.37
1.3
1.4
—
—
—
0
0
229
1992
1.16
1.37
1.2
1.2
—
—
—
0
0
87
691
1.27
1.33
1.1
1.1
—
—
—
0
0
17
284
0.60
1.33
1.4
1.6
883.78
920.50
mu/l
0.07
12
244
196
1689
1.17
1.32
2.3
2.2
10.70
11.99
nmol/l
1.24
170
1474
26
168
1.55
1.31
2.2
1.9
68.58
71.71
%
0.36
26
153
73
569
1.29
1.30
1.2
1.2
4.03
3.86
mmol/l
0.51
68
530
35
242
1.45
1.30
1.1
1.2
—
—
—
0
0
21
129
1.63
1.29
1.1
1.6
5.13
2.11
%
0.36
15
106
61
464
1.32
1.29
1.6
1.5
—
—
—
0
0
14
76
1.85
1.29
1.1
1.2
—
—
—
0
0
53
396
1.34
1.27
1.8
1.4
15.82
11.19
u/l
0.73
34
318
11
55
2.00
1.27
1.0
1.0
16.34
16.31
umol/l
0.01
11
44
33
227
1.46
1.26
1.8
2.2
15.13
16.07
%
1.00
33
227
14
242
0.58
1.25
2.6
2.8
—
—
—
0
0
43
314
1.37
1.20
3.2
2.3
1.92
1.50
u/field
0.15
26
159
158
1351
1.18
1.20
3.0
2.7
—
—
—
0
0
49
366
1.34
1.19
1.1
1.1
—
—
—
0
0
16
94
1.71
1.17
1.7
2.0
26.75
30.59
%
0.51
16
94
11
57
1.93
1.17
1.3
1.9
3.31
1.30
ug/l
0.74
11
51
26
381
0.68
1.16
3.3
2.1
54.72
799.11
u/ml
0.56
26
374
22
142
1.55
1.14
1.3
4.8
45.93
63.29
mg/l
1.57
15
96
111
1323
0.83
1.11
2.0
2.0
3.30
3.40
ratio
0.43
90
1065
23
151
1.53
1.11
1.0
1.1
2.24
2.37
u/ml
0.03
11
68
252
2245
1.13
1.11
5.7
6.2
24.29
24.56
mmol/l
0.47
235
2156
7
32
2.19
1.08
1.3
1.0
—
—
—
0
0
29
202
1.44
1.07
1.6
2.7
7.54
7.01
mmol/l
0.38
21
141
16
97
1.65
1.06
1.8
1.9
6.75
7.18
%
0.08
16
91
20
129
1.55
1.05
1.3
1.4
4.33
3.17
%
—
6
24
67
534
1.26
1.05
1.5
1.5
1515.75
3664.75
e6/l
0.68
51
374
30
212
1.42
1.03
2.2
2.2
—
—
—
0
0
19
288
0.66
1.03
1.4
1.2
0.60
0.63
ratio
—
8
53
145
1253
1.16
1.00
4.4
3.9
24.29
24.91
mmol/l
1.26
119
1121
86
709
1.22
1.00
1.2
1.2
5.42
3.80
u/ml
0.23
11
65
9
48
1.88
1.00
41.3
7.6
7.37
5.26
kpa
—
9
48
60
476
1.27
0.99
1.5
1.4
27068.85
56576.16
e6/l
1.16
34
275
86
711
1.21
0.98
1.2
1.2
2.52
7.68
u/ml
1.73
12
116
5
23
2.18
0.98
1.2
1.0
—
—
—
0
0
19
124
1.54
0.96
2.3
1.4
15.72
10.21
ug/l
0.26
19
106
79
948
0.83
0.90
1.7
1.8
2.96
3.37
mmol/l
2.54
53
684
6
29
2.07
0.89
1.2
1.2
—
—
—
0
0
12
71
1.69
0.88
1.1
1.5
56.00
478.23
nmol/24h
0.55
12
71
742
7044
1.07
0.86
1.4
1.3
—
—
—
0
0
23
161
1.43
0.86
1.1
1.0
2.21
1.70
u/ml
0.18
11
83
55
680
0.81
0.85
1.1
1.1
—
—
—
0
0
199
1786
1.12
0.83
1.2
1.3
—
—
—
0
0
14
89
1.58
0.81
1.6
1.6
0.00
0.07
estimate
0.80
14
89
21
147
1.43
0.80
4.1
4.2
—
—
—
0
0
15
224
0.67
0.80
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
1.43
—
0
15
20
139
1.44
0.79
4.3
4.3
—
—
—
0
0
24
173
1.39
0.78
1.3
1.2
0.58
2.41
u/ml
1.14
13
99
12
74
1.62
0.78
1.4
1.5
6.79
6.73
mmol/l
0.02
12
74
28
208
1.35
0.77
1.1
1.0
534.63
668.61
ng/l
1.55
19
131
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
16
107
1.50
0.76
1.2
1.2
—
0.10
g/l
—
0
9
14
91
1.54
0.75
10.9
6.2
25.21
24.55
mmol/l
0.35
14
80
55
450
1.23
0.74
2.7
2.2
21.25
23.96
mg/l
0.22
20
156
113
987
1.15
0.74
4.3
4.8
—
—
—
0
0
53
433
1.23
0.73
1.5
1.5
—
—
—
0
0
346
3219
1.08
0.72
2.4
2.5
7.65
6.71
ug/l
0.24
281
2714
20
142
1.41
0.72
1.1
1.0
—
—
—
0
0
13
84
1.55
0.71
2.7
2.1
—
—
—
0
0
7
40
1.75
0.71
1.6
1.1
—
—
—
0
0
20
275
0.73
0.70
2.0
2.0
—
—
—
0
0
7
42
1.67
0.68
1.9
1.1
63.13
44.56
mg/l
—
7
33
7
42
1.67
0.68
1.3
1.2
10.96
16.01
g/l
—
7
36
9
59
1.53
0.68
1.1
1.3
24.33
28.11
s
—
9
59
9
59
1.53
0.68
41.4
7.4
5.75
6.01
kpa
—
9
48
11
69
1.60
0.68
3.2
1.9
7.36
7.83
%
0.06
11
58
27
205
1.32
0.67
3.6
5.6
265.42
34.21
u/ml
—
5
63
78
669
1.17
0.66
1.6
2.4
31.13
32.35
umol/l
0.11
63
585
5
28
1.79
0.66
1.2
1.9
—
—
—
0
0
86
989
0.87
0.64
4.6
3.7
3.89
3.89
mmol/l
0.00
86
979
22
163
1.35
0.64
1.9
1.5
—
—
—
0
0
32
251
1.28
0.64
1.0
1.1
0.95
2.39
eliau/ml
—
10
76
27
207
1.31
0.63
1.1
1.0
278.10
310.66
ng/l
0.39
20
135
13
188
0.69
0.62
1.0
1.3
—
—
—
0
0
33
262
1.26
0.61
1.4
1.4
44.81
29.39
%
0.92
15
166
26
334
0.78
0.60
1.5
1.2
1.52
1.54
g/l
0.19
26
334
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
132
1188
1.12
0.58
3.3
3.0
294.30
328.95
mg/l
0.18
57
461
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
6
35
1.72
0.57
1.2
1.8
—
—
—
0
0
59
503
1.18
0.56
1.1
1.4
—
17.80
—
0
9
154
1402
1.10
0.56
1.2
1.2
83.10
126.12
u/ml
1.33
41
485
17
124
1.37
0.55
1.3
1.2
—
—
—
0
0
11
74
1.49
0.53
1.5
1.1
—
—
—
0
0
9
63
1.43
0.52
1.4
1.5
—
—
—
0
0
173
1596
1.09
0.49
2.2
2.2
—
—
—
0
0
93
832
1.12
0.48
1.1
1.2
—
—
—
0
0
11
155
0.71
0.48
1.0
1.1
—
—
—
0
0
27
218
1.24
0.46
2.4
2.5
—
—
—
0
0
12
165
0.73
0.46
1.3
1.5
—
—
—
0
0
266
2508
1.07
0.44
3.8
3.2
6.14
6.09
ph
0.45
181
1802
44
376
1.17
0.44
2.9
4.4
340.91
340.04
umol/l
0.01
35
322
29
238
1.22
0.44
1.2
1.3
7.38
7.42
ph
0.42
23
163
9
128
0.70
0.43
1.1
1.5
—
—
—
0
0
23
184
1.25
0.43
1.0
1.1
0.63
1.28
u/ml
0.59
11
98
9
130
0.69
0.43
1.1
1.6
—
—
—
0
0
197
1842
1.07
0.42
3.8
4.0
1.02
1.02
ratio
1.27
172
1667
90
813
1.11
0.41
1.6
1.6
8349.88
16854.15
e6/l
3.04
65
557
21
167
1.26
0.41
1.0
1.0
—
—
—
0
0
8
58
1.38
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
44
379
1.16
0.41
2.9
2.6
—
—
—
0
0
712
6903
1.04
0.41
5.5
4.9
1.02
1.02
kg/l
2.23
503
4681
70
624
1.12
0.41
1.4
1.2
29.28
42.98
u/l
0.66
55
539
110
1006
1.10
0.40
3.9
3.4
1.49
1.69
mmol/l
1.68
105
984
22
177
1.24
0.40
1.4
1.1
—
—
—
0
0
193
1809
1.07
0.40
4.8
3.3
24.47
25.21
mmol/l
1.62
182
1760
7
103
0.68
0.39
1.1
1.3
140.43
138.33
mmol/l
—
7
81
7
106
0.66
0.39
2.3
1.3
33.86
29.38
umol/l
—
7
98
34
288
1.18
0.39
1.3
1.2
414.78
320.35
nmol/l
1.95
27
225
12
159
0.75
0.38
2.7
2.4
47.17
39.36
%
—
6
89
13
170
0.76
0.38
1.5
1.6
81.38
89.27
umol/l
0.51
13
170
95
867
1.10
0.37
4.1
3.5
8.16
7.79
mmol/l
0.30
90
847
13
98
1.33
0.37
3.0
2.9
26.38
29.74
umol/l
—
8
69
9
70
1.29
0.36
2.8
1.8
27.11
29.05
%
—
9
62
53
469
1.13
0.36
2.7
2.7
—
—
—
0
0
40
348
1.15
0.34
2.0
2.2
—
—
—
0
0
22
265
0.83
0.34
1.2
1.2
—
—
—
0
0
40
349
1.15
0.33
3.8
4.5
—
—
—
0
0
24
200
1.20
0.33
2.4
2.2
2.11
1.81
ug/l
0.42
19
169
170
1600
1.07
0.33
4.3
3.9
—
—
—
0
0
6
87
0.69
0.33
1.0
1.0
—
4.15
—
0
11
6
90
0.67
0.32
2.7
1.5
—
—
—
0
0
42
369
1.14
0.32
1.1
1.1
42.50
71.93
iu/ml
—
8
66
20
164
1.22
0.32
2.0
1.9
2.79
2.79
u/field
0.00
14
111
25
211
1.19
0.31
1.9
1.6
113.08
102.19
ng/l
0.30
25
211
290
2780
1.05
0.30
3.0
2.5
0.38
0.57
e6/l
0.87
278
2681
13
164
0.79
0.30
2.4
2.5
—
—
—
0
0
7
100
0.70
0.30
3.4
1.7
—
—
—
0
0
10
75
1.33
0.30
1.0
1.3
1.64
1.35
mmol/l
—
5
49
11
84
1.31
0.30
1.1
1.0
—
—
—
0
0
11
84
1.31
0.30
1.1
1.0
—
—
—
0
0
11
84
1.31
0.30
1.1
1.0
—
—
—
0
0
7
57
1.23
0.29
1.3
1.1
—
—
—
0
0
67
612
1.10
0.28
1.6
1.5
—
—
—
0
0
11
85
1.30
0.28
1.2
1.3
43.00
31.26
%
—
5
62
129
1223
1.06
0.23
1.3
1.4
—
—
—
0
0
15
125
1.20
0.22
1.2
1.3
—
—
—
0
0
25
219
1.14
0.22
2.3
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.11
—
0
6
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.03
—
0
7
123
1291
0.95
0.20
2.7
3.0
1592.47
2178.35
u/ml
0.18
108
1092
22
193
1.14
0.19
1.4
1.1
—
—
—
0
0
381
3719
1.03
0.18
5.3
5.2
33.57
33.89
%
0.21
234
2331
15
128
1.17
0.18
1.0
1.1
148.13
138.28
nmol/l
0.40
15
128
7
60
1.17
0.17
2.0
1.4
—
—
—
0
0
27
244
1.11
0.16
4.7
3.2
—
—
—
0
0
16
139
1.15
0.16
1.1
1.0
0.02
0.42
u/ml
—
6
51
76
720
1.06
0.16
1.2
1.3
—
—
—
0
0
31
339
0.91
0.16
3.6
4.4
29.33
58.45
u/ml
1.77
31
333
6
77
0.78
0.15
3.8
2.4
3.50
445.08
ug/l
—
6
77
78
821
0.95
0.15
1.3
1.5
0.29
0.31
mg/l
0.08
27
333
344
3366
1.02
0.15
5.6
4.7
7.37
7.36
ph
0.18
230
2378
26
236
1.10
0.14
1.0
1.1
—
—
—
0
0
7
89
0.79
0.14
1.3
2.1
18.29
107.73
ug/l
—
7
81
33
304
1.09
0.14
1.3
1.2
198604.22
161951.23
e6/l
0.07
18
200
24
264
0.91
0.14
1.5
1.4
—
58.10
—
0
21
38
353
1.08
0.14
2.0
2.0
—
—
—
0
0
26
237
1.10
0.14
1.0
1.1
—
—
—
0
0
17
151
1.13
0.13
1.1
1.1
—
—
—
0
0
28
257
1.09
0.13
1.1
1.1
0.60
1.50
u/ml
1.06
13
139
36
386
0.93
0.12
1.3
1.3
—
—
—
0
0
24
259
0.93
0.10
1.2
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
—
—
0
0
110
1131
0.97
0.09
3.6
3.4
0.76
0.83
nmol/l
1.71
93
898
66
685
0.96
0.09
1.2
1.2
80.00
104.04
titre
—
8
52
16
175
0.91
0.08
1.0
1.1
2.50
9.49
nmol/l
—
7
45
16
146
1.10
0.08
5.7
6.8
15.96
150.46
ug/l
0.54
11
86
69
714
0.97
0.08
2.2
3.3
307.23
1089.85
u/ml
1.11
63
645
41
391
1.05
0.08
2.1
2.6
9.46
10.71
mmol/l
1.98
41
386
33
314
1.05
0.07
1.1
1.2
—
—
—
0
0
144
1413
1.02
0.07
3.2
4.0
195.18
90.77
u/ml
0.49
136
1362
8
90
0.89
0.06
1.3
1.4
192.36
154.46
pmol/l
—
8
90
31
297
1.04
0.05
1.7
1.8
—
—
—
0
0
20
210
0.95
0.03
1.1
1.0
0.41
2.04
u/ml
—
8
90
26
270
0.96
0.03
1.3
1.2
—
—
—
0
0
43
421
1.02
0.02
1.1
1.2
—
—
—
0
0
71
720
0.99
0.02
3.8
3.8
30.37
28.07
mg/l
0.27
57
529
379
3805
1.00
0.02
3.7
3.9
19.16
27.01
ug/l
0.36
314
3156
39
382
1.02
0.01
1.5
1.4
—
—
—
0
0
39
382
1.02
0.01
1.5
1.4
—
—
—
0
0
39
382
1.02
0.01
1.5
1.4
—
—
—
0
0
39
382
1.02
0.01
1.5
1.4
—
—
—
0
0
20
206
0.97
0.00
1.1
1.5
—
—
—
0
0
22
214
1.03
0.00
1.1
1.0
3.52
3.58
u/ml
0.01
13
104
34
346
0.98
0.00
1.1
1.1
—
—
—
0
0
62
614
1.01
0.00
1.2
1.2
—
—
—
0
0
13
129
1.01
0.00
1.1
1.3
1.47
315.68
ug/l
—
6
65
22
221
1.00
0.00
1.0
1.1
—
—
—
0
0
45
449
1.00
0.00
1.9
2.5
—
—
—
0
0
15
146
1.03
0.00
1.4
1.6
38.20
38.92
g/l
0.15
15
146
25
246
1.02
0.00
1.8
1.9
7.77
8.30
mmol/l
0.43
25
246
25
254
0.98
0.00
1.6
1.2
92.44
107.85
pmol/l
0.72
25
254
57
567
1.01
0.00
1.6
1.7
—
—
—
0
0
7
70
1.00
0.00
1.0
1.7
5.57
13.29
mm/h
—
7
70
6
67
0.90
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
239.36
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3260.00
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
11
110
1.00
-0.00
5.5
4.1
59.05
53.66
%
0.25
11
104
0
5
0.00
-0.00
0.0
1.0
—
0.29
—
0
5
9
93
0.97
-0.00
2.0
1.3
2.22
1.91
umol/l
—
9
81
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
177.40
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
4.39
—
0
9
8
89
0.90
-0.00
1.4
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
1.77
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
351.00
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
9
95
0.95
-0.00
1.4
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
89
0.90
-0.00
4.1
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_GLAUCOMAMEDICATION and mortality.

Females

Parameter HR [95% CI] p-value
H7_GLAUCOMAMEDICATION 0.897 [0.84, 0.96] 0.002
Birth year 0.99 [0.98, 1.0] 0.019

During the follow-up period (1.1.1998 — 31.12.2019), 5847 out of 15112 females with H7_GLAUCOMAMEDICATION died.

Males

Parameter HR [95% CI] p-value
H7_GLAUCOMAMEDICATION 0.969 [0.89, 1.06] 0.483
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 3519 out of 9395 males with H7_GLAUCOMAMEDICATION died.

Mortality risk

Mortality risk for people of age

years, who have H7_GLAUCOMAMEDICATION.

N-year risk Females Males
1 0.089% 0.153%
5 0.487% 1.08%
10 1.161% 2.555%
15 2.208% 5.031%
20 3.784% 8.639%

Relationships between endpoints

Index endpoint: H7_GLAUCOMAMEDICATION – Use of antiglaucoma preparations and miotics

GWS hits: 13

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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