No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
191 |
4. Check minimum number of eventsNone |
191 |
5. Include endpointsNone |
191 |
6. Filter based on genotype QC (FinnGen only) |
177 |
Control definitions (FinnGen only)
- Control exclude
- Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q3[8-9]|Q4[0-5]
- Name in latin
- Malformationes congenitae oesophagi
Similar endpoints
↥List of similar endpoints to
Congenital malformations of oesophagus
based on the number of shared cases.
Similar with more cases:
- Other congenital malformations of the digestive system
- Other congenital malformations of the digestive system, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1406 | 640 | 758 |
| Only index persons | 1057 | 489 | 568 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 21.73 | 34.07 | 10.71 |
| Only index persons | 35.77 | 49.40 | 24.03 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 177 | 78 | 99 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 61.11 | 57.92 | 63.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 181
- Matched controls
- 1810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q39.6
ICD-10 Finland
Diverticulum of oesophagus
+∞
105.9
91
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
12.2
62.1
130
313
K22.5
ICD-10 Finland
Diverticulum of oesophagus, acquired
131.6
39.6
41
*
R13
ICD-10 Finland
Dysphagia
10.0
39.2
53
72
Q39.11
ICD-10 Finland
Atresia of oesophagus with broncho-oesophageal fistula
+∞
36.7
34
*
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
66.7
29.3
33
6
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
77.1
29.0
32
5
UGC02
NOMESCO Finland
Rigid bronchoscopy
114.4
27.5
29
*
Q39.0
ICD-10 Finland
Atresia of oesophagus without fistula
+∞
22.3
21
*
Q39.10
ICD-10 Finland
Atresia of oesophagus with broncho-oesophageal fistula
+∞
21.3
20
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
5.9
18.8
39
81
UJD02
NOMESCO Finland
Gastroscopy
8.4
17.9
25
34
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.0
17.5
35
70
75020
ICD-8 Finland
Other congenital anomalies of upper alimentary tract, Atresia oesophagi
+∞
15.9
15
*
UJC12
NOMESCO Finland
Flexible oesophagoscopy
49.7
15.4
18
*
Q39.19
ICD-10 Finland
Atresia of oesophagus with tracheo/broncho-oesophageal fistula
+∞
14.8
14
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
14.7
74
298
ZXD10
NOMESCO Finland
Scheduled procedure
3.3
14.4
95
450
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
37.3
13.8
17
5
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
4.8
13.8
35
86
Q39.9
ICD-10 Finland
Congenital malformation of oesophagus, unspecified
+∞
13.7
13
*
JCA60
NOMESCO Finland
Transcervical excision of diverticulum of oesophagus
150.8
13.6
14
*
Q39.88
ICD-10 Finland
Other congenital malformations of oesophagus
+∞
12.6
12
*
Q39.3
ICD-10 Finland
Congenital stenosis and stricture of oesophagus
+∞
12.6
12
*
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
29.0
12.3
16
6
A02BC05
ATC
esomeprazole; systemic
3.0
11.7
86
422
A03FA02
ATC
cisapride; oral, rectal
5.0
11.6
27
61
7503C
ICD-9 Finland
Other congenital anomalies of upper alimentary tract, Tracheooesophageal fistula, oesophageal atresia and stenosis[RUOKATORVIATRESIA ALAFISTELEINEEN]
+∞
11.6
11
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
5.0
11.1
26
59
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
46.3
11.1
13
*
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
116.5
10.5
11
*
JCE31
NOMESCO Finland
Treatment esophageal atresia
+∞
10.5
10
*
WX402
NOMESCO Finland
General anaesthesia
2.9
9.8
62
276
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
9.4
103
602
ZXE00
NOMESCO Finland
One hour or less
2.6
9.3
90
495
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
9.1
73
366
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.4
9.0
18
21
UJC02
NOMESCO Finland
Rigid oesophagoscopy
25.5
9.0
12
5
Z2221
NOMESCO Finland
Medical doctor
2.7
8.9
66
317
A02BC01
ATC
omeprazole; systemic
2.7
8.7
63
299
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.8
8.6
54
237
K22.2
ICD-10 Finland
Oesophageal obstruction
21.3
8.6
12
6
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
8.6
78
413
XG413
NOMESCO Finland
Spirometry with oscillometry
13.7
8.5
14
11
1323
FHL
Esophagoscopy and dilatation
94.3
8.5
9
*
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
+∞
8.4
8
*
7503A
ICD-9 Finland
Other congenital anomalies of upper alimentary tract, Tracheooesophageal fistula, oesophageal atresia and stenosis[RUOKATORVIATRESIA ILMAN FISTELIÄ]
+∞
8.4
8
*
T18.1
ICD-10 Finland
Foreign body in oesophagus
18.2
8.2
12
7
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
18.2
8.2
12
7
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.2
8.1
23
61
R4110
NOMESCO Finland
Physiotherapy
2.6
7.9
65
326
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
7.8
49
214
TJD20
NOMESCO Finland
Change of gastrostomy tube
19.4
7.7
11
6
J45.1
ICD-10 Finland
Nonallergic asthma
3.5
7.6
28
89
ZXD20
NOMESCO Finland
Day surgery
3.3
7.4
30
102
Q39.80
ICD-10 Finland
Duplication of oesophagus
+∞
7.3
7
*
1304
FHL
Esophagogastroduodenoscopy and other therapeutic procedure
+∞
7.3
7
*
K22.8
ICD-10 Finland
Other specified diseases of oesophagus
+∞
7.3
7
*
1310
FHL
Esophagogastroscopy
+∞
7.3
7
*
ZXD05
NOMESCO Finland
Urgent procedure
2.4
7.2
70
376
Z3226
NOMESCO Finland
Physiotherapist
2.6
7.2
50
230
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.6
7.2
50
230
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
7.0
30
105
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.0
6.9
20
54
R03DC03
ATC
montelukast; oral
2.8
6.8
40
168
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
41.7
6.8
8
*
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
23.5
6.7
9
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.2
6.7
28
97
JDB00
NOMESCO Finland
Gastrostomy
72.3
6.5
7
*
JBC00
NOMESCO Finland
Gastro-oesophageal antireflux operation
72.3
6.5
7
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.7
6.3
40
174
Q87.26
ICD-10 Finland
VATER association
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
92
603
2.07
5.44
2.4
2.0
93.36
96.72
pmol/l
0.31
48
311
65
384
2.08
5.00
4.2
2.7
—
—
—
0
0
108
781
1.95
4.54
8.1
9.6
1.21
1.21
mmol/l
0.40
97
688
30
133
2.51
4.53
1.6
1.4
—
—
—
0
0
119
899
1.94
4.29
7.6
11.4
4.52
4.17
e9/l
0.50
98
782
96
686
1.85
4.01
4.3
3.2
—
—
estimate
—
0
0
48
278
1.99
3.78
4.5
3.6
296.80
500.44
ng/l
0.41
40
216
64
411
1.86
3.69
1.7
1.6
20.98
20.80
nmol/l
0.03
53
347
14
47
3.14
3.49
4.3
3.4
2.71
3.34
index
—
7
30
70
470
1.80
3.46
2.9
3.4
0.24
0.38
e6/l
0.69
53
338
117
917
1.78
3.35
7.6
6.7
6.29
6.80
mmol/l
2.34
111
874
55
356
1.78
3.02
2.6
3.5
341.21
350.64
umol/l
0.32
48
316
62
421
1.72
2.86
2.7
2.5
2.74
2.85
mg/l
0.13
56
373
102
792
1.66
2.82
7.1
7.4
13.74
13.03
umol/l
0.16
97
759
95
730
1.63
2.69
8.9
9.0
1.21
1.21
mmol/l
0.06
90
682
64
465
1.58
2.18
3.1
3.5
684.52
1593.43
ng/l
4.04
59
390
77
584
1.55
2.18
3.2
3.8
—
—
—
0
0
43
286
1.66
2.09
2.5
2.9
2.47
2.47
mmol/l
0.08
38
252
41
270
1.67
2.06
2.8
3.1
1.49
2.57
e6/l
0.51
21
133
83
650
1.51
1.99
2.5
2.7
76.70
75.40
nmol/l
0.13
76
588
8
28
2.94
1.88
1.3
1.3
—
—
—
0
0
141
1246
1.60
1.84
23.7
16.6
82.49
81.61
ml/min/173m2
0.20
134
1140
6
20
3.07
1.59
2.5
2.6
1.33
0.75
index
—
6
20
157
1439
1.69
1.59
25.5
17.6
26.64
25.02
mg/l
0.31
143
1173
13
64
2.11
1.58
1.5
2.0
31.77
39.48
u/l
0.96
13
56
41
292
1.52
1.49
2.3
3.0
0.52
0.84
e6/l
0.73
21
153
9
38
2.44
1.48
2.0
1.2
—
—
—
0
0
5
16
3.18
1.45
1.4
1.3
—
—
—
0
0
37
260
1.53
1.42
2.0
1.9
—
—
—
0
0
11
53
2.15
1.41
1.9
2.9
—
—
—
0
0
110
949
1.41
1.41
3.5
3.8
49.57
50.68
u/l
0.05
104
905
29
193
1.60
1.40
2.0
1.9
—
—
—
0
0
38
271
1.51
1.37
1.8
2.9
29.24
29.64
s
0.23
38
264
29
195
1.58
1.35
2.1
1.8
—
—
—
0
0
11
55
2.06
1.30
2.5
3.2
1215.55
633.41
u/ml
0.18
11
46
8
36
2.28
1.26
1.3
1.3
—
—
—
0
0
8
36
2.28
1.26
1.3
1.3
—
—
—
0
0
5
19
2.68
1.22
1.6
1.2
—
—
—
0
0
57
450
1.39
1.20
2.5
2.2
192.49
241.04
u/l
0.29
57
436
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
7
31
2.31
1.11
1.3
1.5
—
—
—
0
0
9
161
0.54
1.03
1.0
1.9
—
—
—
0
0
165
1566
1.61
1.01
34.0
26.0
4.43
4.51
e12/l
1.00
160
1533
165
1566
1.61
1.01
34.1
26.1
254.70
249.81
e9/l
0.41
160
1538
25
175
1.50
0.99
8.3
6.6
1.24
1.54
mmol/l
0.18
18
130
41
316
1.38
0.99
2.0
2.4
1.24
1.60
mg/l
0.47
31
267
8
42
1.95
0.90
1.0
1.6
—
—
—
0
0
8
44
1.86
0.87
1.8
2.6
29.15
179.04
mg/l
—
8
37
8
44
1.86
0.87
1.8
2.6
25.04
33.71
mg/l
—
8
37
8
45
1.81
0.85
1.4
1.4
—
—
—
0
0
20
139
1.49
0.83
3.0
3.4
0.09
0.17
e6/l
0.73
20
134
106
953
1.27
0.83
3.5
3.3
—
—
—
0
0
29
218
1.39
0.82
1.3
1.3
162.91
7.43
u/ml
0.51
11
87
15
100
1.55
0.75
2.1
6.4
1.23
1.23
%
0.01
15
100
32
251
1.33
0.70
1.5
1.3
42.37
25.81
iu/ml
0.27
11
75
37
453
0.77
0.69
2.6
4.3
0.00
0.00
estimate
—
10
154
14
94
1.53
0.69
1.4
1.7
—
—
—
0
0
5
28
1.81
0.66
3.6
3.1
304.80
191.30
e6/l
—
5
20
10
153
0.63
0.66
4.6
8.1
—
—
—
0
0
12
176
0.66
0.66
1.1
2.1
—
—
—
0
0
5
29
1.74
0.64
1.4
11.2
—
4176.67
—
0
6
156
1491
1.34
0.63
13.4
12.1
24.47
26.41
u/l
0.66
151
1458
31
247
1.31
0.62
1.5
1.7
914.81
1260.83
nmol/l
1.83
22
198
5
30
1.69
0.62
1.0
1.4
—
—
—
0
0
14
97
1.48
0.61
2.1
6.5
0.64
0.62
%
0.03
14
97
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
12
81
1.52
0.58
3.3
14.1
0.98
1.28
mg/l
1.71
12
75
117
1089
1.21
0.56
5.5
4.4
13.04
11.52
mm/h
0.60
110
1023
9
59
1.55
0.56
1.0
1.3
—
—
—
0
0
20
152
1.36
0.55
3.6
8.1
22.87
23.78
mmol/l
0.69
20
152
9
62
1.47
0.54
1.3
1.5
—
—
—
0
0
9
62
1.47
0.54
1.3
1.6
—
—
—
0
0
51
584
0.82
0.53
3.8
4.2
0.22
0.00
estimate
—
9
140
7
49
1.45
0.46
1.7
2.2
—
—
—
0
0
7
49
1.45
0.46
1.0
1.3
—
—
—
0
0
7
51
1.39
0.44
1.0
1.3
—
2.61
—
0
9
35
297
1.22
0.44
2.9
3.2
0.80
0.77
ug/l
0.06
26
199
5
33
1.53
0.41
1.2
1.3
—
—
—
0
0
33
281
1.21
0.40
1.6
1.9
467.65
465.35
pmol/l
0.01
26
237
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
5
36
1.40
0.38
1.4
1.3
—
—
—
0
0
24
199
1.24
0.37
2.7
6.8
4.90
4.79
kpa
0.12
24
193
130
1245
1.16
0.35
3.9
4.3
1.13
1.26
mmol/l
2.28
121
1150
6
46
1.31
0.33
1.2
1.7
—
—
—
0
0
6
46
1.31
0.33
1.3
1.5
0.00
0.00
g/l
—
6
41
41
459
0.86
0.32
3.5
4.2
3.70
10.60
mg/mmol
2.90
31
310
7
99
0.70
0.31
1.0
1.1
—
—
—
0
0
7
52
1.36
0.31
1.1
1.6
—
—
—
0
0
15
121
1.26
0.29
2.1
1.8
—
—
—
0
0
22
187
1.20
0.28
2.7
4.1
7.50
10.39
umol/l
0.39
22
161
5
41
1.23
0.22
1.2
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
3.7
—
—
—
0
0
0
11
0.00
0.21
0.0
3.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
1009.20
—
0
10
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
32.00
—
0
6
0
12
0.00
0.21
0.0
1.0
—
662.00
—
0
7
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
218.08
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
84
800
1.09
0.21
3.3
4.1
137.09
0.00
estimate
0.47
11
166
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
11
90
1.24
0.19
2.9
1.4
—
—
—
0
0
6
51
1.18
0.19
1.8
2.0
—
—
—
0
0
13
152
0.84
0.17
1.2
1.3
—
—
—
0
0
5
67
0.74
0.17
3.4
5.8
75.20
89.24
%
—
5
67
55
523
1.07
0.13
6.2
5.6
2.65
2.04
ug/l
0.50
50
464
125
1277
0.93
0.13
5.8
6.5
37.33
39.58
mmol/mol
3.86
119
1205
82
794
1.06
0.11
3.2
4.1
0.00
0.00
estimate
—
10
169
5
44
1.14
0.10
2.0
1.4
—
121.26
—
0
16
43
410
1.06
0.09
3.7
3.8
0.22
0.00
estimate
—
9
136
5
47
1.07
0.09
1.2
1.2
—
—
—
0
0
5
48
1.04
0.09
1.2
1.2
—
—
—
0
0
130
1319
0.95
0.08
4.8
5.0
4.32
4.46
mmol/l
1.03
121
1232
24
225
1.08
0.08
3.3
7.0
5.49
5.77
kpa
1.29
24
218
6
73
0.82
0.08
2.2
1.3
—
—
—
0
0
135
1334
1.05
0.06
5.6
5.6
2.50
2.62
mmol/l
1.08
125
1245
17
182
0.93
0.06
1.8
2.5
397.00
385.04
nmol/l
0.08
17
170
82
804
1.04
0.06
3.4
4.2
0.00
0.03
estimate
—
10
152
113
1116
1.03
0.05
3.7
4.1
14.87
14.81
pmol/l
0.08
108
1023
130
1313
0.96
0.04
4.9
5.1
1.90
1.95
mu/l
0.15
123
1212
18
170
1.07
0.04
2.4
1.6
1.50
1.52
%
0.06
18
144
130
1311
0.97
0.03
4.7
4.8
1.42
1.41
mmol/l
0.15
121
1217
128
1288
0.98
0.01
5.0
5.0
5.78
5.96
mmol/l
1.50
118
1193
36
354
1.02
0.00
3.8
4.3
1.02
1.02
kg/l
0.00
24
230
41
414
0.99
0.00
5.3
4.7
23.02
21.82
%
0.22
22
213
31
309
1.00
0.00
1.5
1.9
—
—
—
0
0
55
551
1.00
0.00
2.1
2.1
1.29
1.32
mmol/l
0.16
48
469
58
577
1.01
0.00
4.8
4.1
27.44
47.53
ng/l
1.27
38
435
16
158
1.01
0.00
4.1
3.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
5.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
7.23
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.7
—
23.65
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
170.14
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
26.67
—
0
6
6
65
0.92
-0.00
1.0
1.5
0.30
0.24
g/l
—
6
65
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
0.03
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.8
—
103.78
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
0.31
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.21
—
0
7
6
65
0.92
-0.00
1.0
1.5
1.48
1.18
g/l
—
6
65
0
7
0.00
-0.00
0.0
1.3
—
67.00
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_OESOPHAGUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_OESOPHAGUS | 1.319 [0.99, 1.76] | 0.062 |
| Birth year | 0.992 [0.98, 1.0] | 0.098 |
During the follow-up period (1.1.1998 — 31.12.2019), 92 out of 492 females with Q17_CONGEN_MALFO_OESOPHAGUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_OESOPHAGUS | 1.592 [1.12, 2.26] | 0.009 |
| Birth year | 0.988 [0.98, 1.0] | 0.033 |
During the follow-up period (1.1.1998 — 31.12.2019), 92 out of 579 males with Q17_CONGEN_MALFO_OESOPHAGUS died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_OESOPHAGUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.147% | 0.364% |
| 5 | 0.706% | 2.122% |
| 10 | 1.784% | 5.113% |
| 15 | 3.469% | 8.932% |
| 20 | 6.047% | 14.384% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_OESOPHAGUS – Congenital malformations of oesophagus
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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