Traction detachment of retina

H7_RETINALDETACHTRACTION

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H33.4
  • Cause of death: ICD-10 H33.4

2 out of 7 registries used, show all original rules.

363

4. Check minimum number of events

None

363

5. Include endpoints

None

363

6. Filter based on genotype QC (FinnGen only)

313

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H33
Name in latin
Ablatio retinae e tractione

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2013 939 1062
Only index persons 1790 849 941
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.03 0.03 0.04
Median age at first event (years)
Whole population 59.71 61.10 58.39
Only index persons 58.66 59.96 57.48

-FinnGen-

Key figures

All Female Male
Number of individuals 313 141 172
Unadjusted period prevalence (%) 0.07 0.05 0.08
Median age at first event (years) 54.46 52.40 56.15

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
324
Matched controls
3240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
307.7
322
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
153.9
247.6
124
13
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
138.3
217.6
110
12
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
87.4
210.7
114
20
A10AB01
ATC
insulin (human); parenteral
49.6
196.8
122
39
H33.0
ICD-10 Finland
Retinal detachment with retinal break
+∞
196.5
168
*
A10AA02, ,
ATC
51.1
189.8
116
35
WX140
NOMESCO Finland
Parabulbar anesthesy
61.2
189.4
110
27
A10AA01, ,
ATC
59.3
180.1
105
26
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
33.7
160.7
112
50
A10AC01
ATC
insulin (human); parenteral
20.4
151.2
141
118
T89
ICPC
Diabetes insulin dependent
30.0
145.2
105
51
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
553.5
142.9
132
*
S01ED51
ATC
timolol, combinations; ophthalmic
19.6
138.9
129
106
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
132.7
118
*
A10AE04
ATC
insulin glargine; parenteral
15.7
131.4
147
163
A10AB04
ATC
insulin lispro; parenteral
38.1
130.9
85
30
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
48.6
129.6
78
21
CKC12
NOMESCO Finland
Photocoagulation of retina
625.6
127.3
118
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
18.8
127.0
118
96
A10AB05
ATC
insulin aspart; parenteral
16.7
126.9
130
125
H04AA01
ATC
glucagon; nasal, parenteral
48.5
124.7
75
20
H3603, E103,
ICD-10 Finland
+∞
122.9
110
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
22.7
112.5
90
54
XCK10
NOMESCO Finland
Photography of fundus of eye
14.8
106.4
113
113
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
12.8
104.5
252
697
A10AE05
ATC
insulin detemir; parenteral
18.0
103.5
94
72
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
1314.1
101.9
94
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
199.6
98.4
98
7
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
98.0
89
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
10.9
96.1
136
201
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
+∞
95.7
87
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
13.7
93.5
102
105
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
87.6
80
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
968.2
80.0
75
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
951.4
78.8
74
*
A10AD01
ATC
insulin (human); parenteral
32.7
75.3
50
18
S01ED01
ATC
timolol; ophthalmic
19.5
73.8
61
38
S01EC01
ATC
acetazolamide; systemic
25.2
72.4
53
25
Z01.0
ICD-10 Finland
Examination of eyes and vision
7.7
71.9
143
301
103
Kela drug reimbursment
Diabetes, insulin-treated
7.1
70.0
190
540
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
22.1
69.8
54
29
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
7.1
68.9
200
603
A10AE06
ATC
insulin degludec; parenteral
16.8
68.3
61
44
215
Kela drug reimbursment
Diabetes, non-insulin-treated
6.9
67.7
174
467
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
+∞
67.0
62
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
29.8
64.5
44
17
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
62.6
58
*
H26.4
ICD-10 Finland
After-cataract
9.1
60.5
87
126
S01EA05
ATC
brimonidine; ophthalmic
20.2
58.7
47
27
H3603, E113,
ICD-10 Finland
+∞
57.0
53
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
22.8
55.6
42
21
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
168.5
54.8
56
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
23.9
54.1
40
19
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
23.2
52.1
39
19
CKC15
NOMESCO Finland
Panretinal photocoagulation
585.4
52.0
50
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
20.6
50.7
40
22
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
80.6
48.8
54
8
CJB10
NOMESCO Finland
Laser discission of secondary cataract
8.5
48.7
71
103
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
273.8
47.3
47
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
267.0
46.3
46
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
45.9
43
*
H36.01
ICD-10 Finland
Diabetic maculopathy
503.5
45.4
44
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
178.0
45.1
46
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
9.1
44.0
59
77
S01BC05
ATC
ketorolac; ophthalmic
10.8
43.0
50
54
A11CC03
ATC
alfacalcidol; systemic
15.8
42.3
38
27
H26.2
ICD-10 Finland
Complicated cataract
104.2
42.0
45
5
H3601, E103,
ICD-10 Finland
+∞
41.6
39
*
SPAT1262
SPAT
Handing over of treatment supplies
5.2
40.8
110
290
H33.3
ICD-10 Finland
Retinal breaks without detachment
+∞
40.5
38
*
XCH00
NOMESCO Finland
Eye pressure measurement
9.9
38.9
48
56
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
38.3
36
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
80.0
38.0
42
6
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
214.4
37.6
38
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
110.5
36.6
39
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
10.1
35.0
42
47
S01EE01
ATC
latanoprost; ophthalmic
7.5
34.9
55
86
H3600, E103,
ICD-10 Finland
+∞
32.9
31
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
+∞
30.7
29
*
H26.02
ICD-10 Finland
Presenil cataract
11.3
29.4
32
31
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
88.6
29.3
32
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
113.9
29.2
31
*
114
Kela drug reimbursment
Glaucoma
5.6
28.7
61
128
S01EA03
ATC
apraclonidine; ophthalmic
58.9
27.7
32
6
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
+∞
27.5
26
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
105.8
27.1
29
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
26.4
25
*
ZXA05
NOMESCO Finland
Left side
3.6
26.0
119
446
A10AA03, ,
ATC
39.2
25.7
32
9
ZXA00
NOMESCO Finland
Right side
3.5
25.6
128
507
Z94.0
ICD-10 Finland
Kidney transplant status
63.4
25.4
29
5
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
97.9
25.1
27
*
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
61.0
24.4
28
5
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
135.0
23.9
25
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
29.9
22.7
30
11
S01EC04
ATC
brinzolamide; ophthalmic
7.5
22.5
34
50
H25.1
ICD-10 Finland
Senile nuclear cataract
3.3
22.4
124
517
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.1
22.2
175
892
127
Kela drug reimbursment
Transplant complication
28.8
21.7
29
11
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
28.8
21.7
29
11
C03CA01
ATC
furosemide; systemic
3.1
21.5
138
624
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.5
21.4
37
63
WX002
NOMESCO Finland
Sedation and analgesia
3.5
21.4
92
327
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
64.5
21.2
24
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.2
21.1
65
183
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
40.2
21.1
26
7
H3603, E106,
ICD-10 Finland
+∞
21.1
20
*
TK800
NOMESCO Finland
Hemodialysis
18.9
20.5
31
18
H3601, E113,
ICD-10 Finland
+∞
20.0
19
*
H33.5
ICD-10 Finland
Other retinal detachments
78.2
19.9
22
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
33.7
19.6
25
8
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
7.0
19.6
31
48
L04AA06
ATC
mycophenolic acid; systemic
18.6
19.1
29
17
S01BA01
ATC
dexamethasone; ophthalmic
7.6
19.0
28
40
H3603, E107,
ICD-10 Finland
+∞
18.9
18
*
C02AC05
ATC
moxonidine; oral
6.3
18.8
33
57
NHQ40
NOMESCO Finland
Amputation of toe
16.6
18.3
29
19
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
55.9
18.2
21
*
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
+∞
17.9
17
*
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
17.9
17
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
39.2
17.8
22
6
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.3
17.8
38
79
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
190.0
17.7
18
*
N18.0
ICD-10 Finland
End-stage renal disease
44.8
17.5
21
5
T90
ICPC
Diabetes non-insulin dependent
2.9
17.4
109
477
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
16.8
16
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
95.1
16.7
18
*
L04AD02
ATC
tacrolimus; systemic
42.5
16.5
20
5
Z49.1
ICD-10 Finland
Extracorporeal dialysis
22.4
16.2
23
11
B03XA02
ATC
darbepoetin alfa; parenteral
15.6
16.1
26
18
C10AA05
ATC
atorvastatin; oral
2.6
15.7
162
904
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
167.8
15.6
16
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.9
15.6
50
144
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.8
15.4
37
85
A12AA04
ATC
calcium carbonate; oral
18.9
15.4
23
13
S01BC03
ATC
diclofenac; ophthalmic
18.9
15.4
23
13
177
Kela drug reimbursment
Insulin glargine 300 U / ml
13.4
15.2
26
21
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
6.9
15.1
24
37
205
Kela drug reimbursment
Chronic hypertension
2.7
14.8
109
513
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
84.0
14.7
16
*
H3602, E103,
ICD-10 Finland
+∞
14.7
14
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
+∞
14.7
14
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
23.6
14.4
20
9
S01EE05
ATC
tafluprost; ophthalmic
6.1
14.4
26
46
C09AA02
ATC
enalapril; systemic
2.8
14.3
89
383
I10
ICD-10 Finland
Essential (primary) hypertension
2.6
14.1
220
1462
S01FA04
ATC
cyclopentolate; ophthalmic
15.6
13.8
22
15
C10AX09
ATC
ezetimibe; oral
2.9
13.7
76
307
H34.8
ICD-10 Finland
Other retinal vascular occlusions
78.5
13.7
15
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
5.6
13.7
27
52
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
35.7
13.6
17
5
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
35.7
13.6
17
5
H35.4
ICD-10 Finland
Peripheral retinal degeneration
+∞
13.6
13
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
+∞
13.6
13
*
V03AE02
ATC
sevelamer; oral
145.9
13.6
14
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
145.9
13.6
14
*
XCK00
NOMESCO Finland
Perimetry
4.6
13.5
34
81
OAB50, ,
SPAT
3.9
13.5
42
118
H25.8
ICD-10 Finland
Other senile cataract
3.5
13.1
49
156
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.1
13.0
62
230
H20.1
ICD-10 Finland
Chronic iridocyclitis
52.2
13.0
15
*
C08CA01
ATC
amlodipine; oral
2.4
12.9
146
831
S01EE03
ATC
bimatoprost; ophthalmic
13.0
12.8
22
18
L84
ICD-10 Finland
Corns and callosities
5.8
12.8
24
44
S01EX03, ,
ATC
15.1
12.4
20
14
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
39.2
12.3
15
*
V03AE01
ATC
polystyrene sulfonate; oral
19.0
12.2
18
10
Z49.0
ICD-10 Finland
Preparatory care for dialysis
22.3
12.1
17
8
C10AA01
ATC
simvastatin; oral
2.3
12.0
150
883
ZXD05
NOMESCO Finland
Urgent procedure
2.4
12.0
121
650
Z3229
NOMESCO Finland
Other healthcare associate professional
3.6
11.8
42
129
S01EC03
ATC
dorzolamide; ophthalmic
17.2
11.8
18
11
S01EC54
ATC
brinzolamide, combinations; ophthalmic
17.2
11.8
18
11
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
11.5
11
*
H3600, E113,
ICD-10 Finland
+∞
11.5
11
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
124.2
11.5
12
*
H40.0
ICD-10 Finland
Glaucoma suspect
3.7
11.4
39
117
J01FF01
ATC
clindamycin; systemic
2.4
11.3
109
572
B05DB
ATC
Hypertonic solutions
44.9
11.0
13
*
137
Kela drug reimbursment
Uraemia requiring dialysis
29.1
10.8
14
5
H54.4
ICD-10 Finland
Blindness, monocular
62.1
10.7
12
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
62.1
10.7
12
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.7
10.6
35
102
XCD10
NOMESCO Finland
Electrophysiological examination of eye
8.7
10.5
22
27
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
113.5
10.5
11
*
H54.0
ICD-10 Finland
Blindness, binocular
+∞
10.5
10
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
10.5
10
*
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
9.3
10.4
21
24
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
10.4
97
499
B05DA
ATC
Isotonic solutions
33.7
10.4
13
*
ZXA10
NOMESCO Finland
Bilateral
2.6
10.4
70
310
H25.0
ICD-10 Finland
Senile incipient cataract
4.0
10.3
30
80
N18.8
ICD-10 Finland
Other chronic renal failure
9.6
10.2
20
22
A46
ICD-10 Finland
Erysipelas
2.6
10.0
64
276
H16.0
ICD-10 Finland
Corneal ulcer
3.9
10.0
30
82
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
11.1
9.9
18
17
ZX198
NOMESCO Finland
Other local administration
20.8
9.9
14
7
S97
ICPC
Chronic ulcer skin
3.5
9.6
35
109
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
15.7
9.6
15
10
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
31.0
9.5
12
*
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
102.9
9.5
10
*
A10AD04
ATC
insulin lispro; parenteral
102.9
9.5
10
*
3643
FHL
Vitrectomy through pars Plana
102.9
9.5
10
*
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
+∞
9.4
9
*
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
14.2
9.3
15
11
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
5.0
9.2
20
42
H04.10
ICD-10 Finland
Dry eye syndrome
2.8
9.1
48
187
196
Kela drug reimbursment
Paricalcitol and cinacalcet
37.8
9.1
11
*
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
8.3
9.0
19
24
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.4
8.7
32
100
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
8.7
127
772
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
51.4
8.7
10
*
C07AB07
ATC
bisoprolol; oral
2.0
8.6
168
1132
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
92.4
8.5
9
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
13.2
8.4
14
11
H53.1
ICD-10 Finland
Subjective visual disturbances
3.3
8.4
33
108
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
8.4
37
130
H35.37
ICD-10 Finland
Macular holes
+∞
8.4
8
*
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
8.4
8
*
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
8.4
8
*
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
8.4
8
*
H3603, E109,
ICD-10 Finland
+∞
8.4
8
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
8.4
8
*
H35.29
ICD-10 Finland
Other proliferative retinopathy
+∞
8.4
8
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
8.3
53
227
A28
ICPC
Limited function/disability NOS
2.3
8.2
69
336
M65.3
ICD-10 Finland
Trigger finger
3.8
8.2
25
69
H27.0
ICD-10 Finland
Aphakia
34.3
8.1
10
*
Z49.2
ICD-10 Finland
Other dialysis
34.3
8.1
10
*
H43.8
ICD-10 Finland
Other disorders of vitreous body
3.1
8.0
35
122
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
8.0
53
232
L17
ICPC
Foot/toe symptom/complaint
2.0
7.8
110
657
E16.0
ICD-10 Finland
Drug-induced hypoglycaemia without coma
46.1
7.7
9
*
TK820
NOMESCO Finland
Peritoneal dialysis
46.1
7.7
9
*
S01BA04
ATC
prednisolone; ophthalmic
7.0
7.7
18
27
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
7.7
82
440
L28
ICPC
Limited function/disability (L)
2.2
7.7
73
374
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.1
7.5
81
436
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
81.9
7.4
8
*
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
7.1
7.4
17
25
H3603, E108,
ICD-10 Finland
+∞
7.3
7
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
30.8
7.2
9
*
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
30.8
7.2
9
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
20.6
7.2
10
5
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
7.1
45
192
XCW10
NOMESCO Finland
Assessment of vision
10.4
7.1
13
13
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
7.0
22
62
J01MA02
ATC
ciprofloxacin; systemic
1.9
7.0
130
847
A10BB12
ATC
glimepiride; oral
3.1
6.9
30
104
C09BA02
ATC
enalapril and diuretics; systemic
2.9
6.8
34
128
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
40.9
6.8
8
*
25008
ICD-8 Finland
Diabetes mellitus, Complicatio alia definita
40.9
6.8
8
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
17.1
6.8
10
6
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.5
6.7
45
197
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
23.1
6.7
9
*
V03AE03
ATC
lanthanum carbonate; oral
23.1
6.7
9
*
3025
Kela drug reimbursment
Calcium carbonate
23.1
6.7
9
*
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.1
6.7
17
29
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
6.4
6.6
16
26
C03DA01
ATC
spironolactone; oral
2.4
6.5
48
220
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
71.2
6.4
7
*
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
4.2
6.4
17
42
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
6.8
6.4
15
23
SPAT1229
SPAT
Assessment of need for aid
2.9
6.3
30
110
CA1ME
NOMESCO Finland
Ultrasound oculometry
18.5
6.3
9
5
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
18.5
6.3
9
5
G63.2
ICD-10 Finland
Diabetic polyneuropathy
18.5
6.3
9
5
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
7.3
6.3
14
20
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
+∞
6.3
6
*
CKD45
NOMESCO Finland
Endocryotherapy of retina
+∞
6.3
6
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
6.3
6
*
H3603, E116,
ICD-10 Finland
+∞
6.3
6
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
6.3
6
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
6.3
6
*
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
6.3
6
*
M14.6
ICD-10 Finland
Neuropathic arthropathy
+∞
6.3
6
*
H57.1
ICD-10 Finland
Ocular pain
3.4
6.3
22
67
XCD20
NOMESCO Finland
Photoangiography of eye
27.2
6.3
8
*
H21.0
ICD-10 Finland
Hyphaema
27.2
6.3
8
*
S01EE04
ATC
travoprost; ophthalmic
6.9
6.1
14
21
A10AB06
ATC
insulin glulisine; parenteral
10.3
6.1
11
11
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
4.0
6.1
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
185
836
3.83
31.49
10.0
4.0
32.94
8.93
mg/mmol
3.20
159
551
178
816
3.62
28.99
8.9
3.3
196.31
56.90
mg/l
3.55
149
541
181
900
3.29
24.71
8.9
3.1
6.16
8.14
mmol/l
10.80
168
775
66
188
4.15
21.12
11.6
3.6
217.89
89.32
ng/l
3.95
58
162
90
360
3.08
16.81
23.1
5.8
1.20
1.02
mmol/l
3.92
85
334
79
310
3.05
15.12
2.8
1.7
—
—
—
0
0
31
62
5.42
15.11
3.9
2.0
575.40
74.54
ug/min
1.20
21
33
96
426
2.78
14.62
7.3
2.5
2.01
2.29
g/l
5.37
91
389
69
264
3.05
13.71
13.9
4.0
0.63
2.11
mmol/l
3.47
63
229
62
237
3.00
12.26
20.7
10.7
—
—
—
0
0
67
274
2.82
11.69
13.8
4.1
7.36
7.39
ph
4.67
46
163
24
52
4.90
10.66
2.7
1.2
158.56
169.87
au/ml
—
9
12
89
437
2.43
10.63
3.7
1.9
—
—
—
0
0
72
322
2.59
10.47
5.5
3.0
2.14
1.86
%
0.59
67
291
49
184
2.96
9.92
6.6
3.2
7.40
7.41
ph
1.19
44
152
24
57
4.47
9.55
2.7
1.3
—
—
—
0
0
49
189
2.88
9.44
7.2
3.2
5.16
5.10
kpa
0.21
49
183
8
0
+∞
8.37
1.9
0.0
2.31
—
mg/l
—
8
0
38
136
3.03
8.34
3.2
2.1
1.66
1.50
g/l
0.47
38
121
23
59
4.12
8.30
1.9
1.2
207.61
252.40
u/ml
0.33
18
30
13
9
14.98
8.27
2.7
1.4
118.92
72.39
ng/l
—
13
9
117
702
2.04
8.24
2.9
2.1
3.15
2.99
mg/l
0.25
105
611
216
1619
2.00
7.86
14.2
5.2
9.08
6.62
mmol/l
18.24
209
1531
55
249
2.46
7.68
5.3
3.0
65.58
68.65
e9/l
0.32
41
182
110
662
2.00
7.57
1.6
1.3
2.51
1.48
u/ml
0.31
36
180
18
28
6.74
7.52
1.3
1.2
—
—
—
0
0
22
59
3.93
7.49
19.2
1.5
0.70
0.93
nmol/l
1.11
16
51
17
38
4.67
7.26
1.4
1.2
—
—
—
0
0
121
767
1.92
7.07
7.7
4.4
—
—
—
0
0
129
842
1.88
6.85
2.9
2.1
194.19
206.81
u/l
0.10
123
803
16
27
6.18
6.39
2.4
2.6
3.34
0.92
g/24h
—
8
19
9
5
18.45
6.30
7.8
6.2
5.49
4.80
mmol/l
—
9
5
164
1180
1.79
6.17
3.8
2.5
70.00
75.29
nmol/l
1.65
150
1066
26
92
2.99
5.82
1.8
1.3
—
—
—
0
0
71
398
2.00
5.81
14.3
8.2
103.49
104.09
mmol/l
0.50
71
398
22
71
3.25
5.73
5.6
2.8
8.20
8.08
kpa
0.10
22
71
109
709
1.81
5.65
5.0
2.9
375.60
350.30
umol/l
1.58
92
632
169
1251
1.73
5.56
15.2
13.5
1.22
1.25
inr
0.33
139
1038
62
337
2.04
5.50
11.0
8.7
7.40
7.41
ph
0.40
33
200
32
131
2.60
5.48
6.9
3.1
—
—
—
0
0
163
1198
1.73
5.48
22.5
6.6
1.20
1.21
mmol/l
0.71
153
1113
132
916
1.74
5.44
7.2
6.2
—
—
—
0
0
14
25
5.80
5.43
4.6
3.6
2266.29
1056.92
mg
0.93
14
25
61
332
2.03
5.39
11.1
8.8
-0.46
1.00
mmol/l
1.57
50
275
177
1337
1.71
5.33
26.6
7.3
1.20
1.21
mmol/l
0.53
160
1165
119
807
1.75
5.29
1.9
1.7
19.17
20.62
nmol/l
0.58
104
689
14
26
5.58
5.28
4.0
1.7
9.16
10.63
%
0.64
14
26
115
775
1.75
5.21
3.6
3.1
—
—
—
0
0
162
1200
1.70
5.21
2.4
2.1
109.22
96.71
pmol/l
2.31
101
648
159
1172
1.70
5.20
12.1
4.8
33.31
35.93
g/l
6.80
151
1112
168
1271
1.67
4.88
6.0
3.1
173.09
129.96
ug/l
1.23
159
1190
27
111
2.56
4.60
2.8
2.3
301.94
311.42
ug/l
0.03
27
106
116
811
1.67
4.47
3.4
3.3
3429.57
1302.74
ng/l
2.29
106
676
169
1300
1.63
4.45
6.8
6.6
59.60
57.87
%
0.97
164
1246
123
879
1.64
4.33
8.4
2.6
55.54
66.91
u/l
0.81
114
825
11
20
5.65
4.32
4.7
2.7
—
—
—
0
0
166
1286
1.60
4.15
6.9
6.7
0.59
0.65
%
0.76
161
1208
8
10
8.17
4.08
2.9
1.6
0.62
0.61
mmol/l
—
8
10
84
551
1.71
4.06
1.7
1.8
198551150.17
24632025.38
pmol/l
0.41
69
475
23
94
2.56
3.98
7.4
4.2
1148.65
205.79
mg/l
1.44
17
42
165
1289
1.57
3.90
6.8
6.6
3.07
2.81
%
0.81
159
1219
89
600
1.67
3.87
1.5
1.4
2.56
2.61
g/l
0.08
46
357
165
1292
1.56
3.84
6.9
6.8
8.65
8.76
%
0.20
159
1226
167
1314
1.56
3.78
6.8
6.7
26.12
27.21
%
0.61
161
1257
59
358
1.79
3.72
3.2
1.6
—
—
—
0
0
42
229
1.96
3.68
1.2
1.2
—
—
—
0
0
58
356
1.77
3.52
1.5
1.4
—
—
—
0
0
42
233
1.92
3.50
15.6
3.8
7.38
7.35
ph
0.61
34
165
174
1397
1.53
3.50
6.4
6.6
0.64
0.58
e9/l
1.78
144
1205
31
154
2.12
3.49
11.6
3.2
0.58
0.64
%
0.57
31
154
206
1722
1.54
3.39
8.3
4.6
35.63
3062.91
e6/l
—
8
22
174
1404
1.52
3.37
6.4
6.6
0.04
0.04
e9/l
0.04
145
1213
276
2477
1.77
3.34
16.0
6.0
52.66
38.89
mmol/mol
29.41
261
2340
10
286
0.33
3.27
1.2
1.4
—
—
—
0
0
118
883
1.53
3.23
8.8
3.2
18.33
117.03
e6/l
0.74
97
671
87
609
1.59
3.19
7.3
2.7
4.86
4.90
e6/l
0.02
81
557
59
374
1.71
3.19
1.2
1.3
—
—
—
0
0
67
443
1.65
3.09
1.8
1.7
1525.45
1206.90
nmol/l
1.62
54
336
178
1460
1.49
3.08
8.2
6.7
10.15
11.85
umol/l
2.22
169
1397
110
819
1.52
3.05
16.0
4.2
7.39
7.39
ph
0.25
92
581
235
2046
1.54
3.01
14.4
8.3
91.61
78.05
u/l
2.56
227
1943
30
157
2.00
2.96
12.4
3.2
1.39
1.30
%
0.19
30
157
176
1451
1.47
2.90
7.2
7.0
0.21
0.19
e9/l
0.55
148
1277
43
256
1.78
2.89
2.5
2.3
0.19
0.22
g/l
0.97
38
235
105
784
1.50
2.85
6.0
3.8
0.00
0.01
estimate
0.74
28
281
173
1427
1.46
2.81
6.6
6.7
1.97
1.93
e9/l
0.10
145
1270
41
243
1.79
2.80
3.0
4.7
0.50
0.51
%
0.01
14
79
23
112
2.13
2.74
1.4
1.5
—
18.56
—
0
5
16
67
2.46
2.67
2.6
1.1
—
—
—
0
0
14
55
2.62
2.65
6.0
3.3
—
—
—
0
0
40
240
1.76
2.63
3.0
5.0
0.08
0.11
%
0.12
12
70
42
256
1.74
2.62
2.9
4.9
0.46
0.73
%
0.57
13
87
11
36
3.13
2.59
1.6
2.9
7.83
107.31
u/ml
0.47
11
36
171
1422
1.43
2.58
5.6
3.6
0.00
0.00
estimate
-0.00
31
305
115
890
1.45
2.56
5.4
3.4
2.34
2.35
mmol/l
0.44
106
814
13
50
2.67
2.56
7.8
2.7
13.84
7.74
pmol/l
1.38
13
50
84
616
1.49
2.45
5.6
3.9
1.02
1.02
kg/l
0.03
52
402
20
97
2.13
2.43
9.2
3.4
24.03
25.02
mmol/l
0.71
20
91
41
254
1.70
2.42
2.5
5.2
0.00
0.17
%
—
10
72
18
84
2.21
2.39
1.4
2.6
1.55
3.45
ratio
—
8
46
19
91
2.16
2.38
1.5
2.7
55.80
29.38
mg/l
1.40
14
78
19
91
2.16
2.38
1.5
2.7
86.49
123.87
mg/l
0.24
14
78
127
1014
1.42
2.35
9.8
3.8
144.47
79.75
e6/l
0.61
99
706
171
1439
1.40
2.33
5.6
3.7
0.00
5.27
estimate
0.50
33
308
31
179
1.81
2.32
1.6
2.2
—
—
—
0
0
171
1447
1.38
2.21
5.6
3.7
0.00
1.06
estimate
0.50
27
287
19
94
2.08
2.21
1.3
1.4
—
—
—
0
0
114
902
1.41
2.20
4.9
2.4
—
—
—
0
0
135
1100
1.39
2.19
2.9
1.9
1.22
1.39
mmol/l
2.33
114
941
184
1580
1.38
2.15
10.1
10.4
4.70
4.11
e9/l
2.33
158
1381
264
2415
1.50
2.15
7.0
5.2
2.03
1.89
mu/l
1.26
247
2235
61
430
1.52
2.14
6.9
2.9
3.59
2.36
e6/l
0.47
36
199
6
15
4.05
2.05
1.0
3.1
25.35
15.73
mu/l
—
6
15
8
27
3.01
1.95
1.4
1.0
—
—
—
0
0
0
52
0.00
1.90
0.0
1.1
—
—
—
0
0
22
122
1.86
1.89
1.2
1.2
—
—
—
0
0
8
28
2.90
1.87
1.3
2.1
—
—
—
0
0
97
765
1.38
1.87
7.3
3.1
0.34
0.31
e6/l
0.12
74
551
8
29
2.80
1.80
1.1
1.6
—
—
—
0
0
145
1225
1.33
1.77
16.8
11.8
0.00
0.00
e9/l
0.12
112
1001
6
18
3.38
1.75
1.2
1.0
—
—
—
0
0
269
2498
1.45
1.75
6.8
4.1
1.34
1.29
mmol/l
0.47
253
2326
128
1064
1.34
1.74
5.5
3.8
616.87
40.11
ng/l
0.53
98
744
28
172
1.69
1.74
6.9
4.1
—
—
—
0
0
8
30
2.71
1.73
1.9
1.6
92.63
89.23
%
—
8
30
8
31
2.62
1.67
1.3
1.4
—
—
—
0
0
7
26
2.73
1.59
1.1
1.3
—
—
—
0
0
5
15
3.37
1.53
4.8
2.2
—
—
—
0
0
0
45
0.00
1.51
0.0
1.2
—
—
—
0
0
64
488
1.39
1.50
3.2
1.6
—
—
—
0
0
80
641
1.33
1.37
5.3
3.5
—
0.29
—
0
7
147
1279
1.27
1.35
4.6
2.8
—
—
estimate
—
0
0
67
528
1.34
1.28
4.8
3.0
494.69
547.51
mosm/kgh2o
0.89
59
467
27
180
1.55
1.25
1.4
1.3
185.89
152.64
u/ml
—
9
71
93
1106
0.78
1.25
5.9
3.0
—
—
—
0
0
217
1992
1.27
1.22
5.3
4.3
14.92
14.73
pmol/l
0.50
201
1841
6
26
2.33
1.19
1.5
1.5
—
—
—
0
0
30
208
1.49
1.18
7.1
3.8
1.21
1.22
mmol/l
0.46
30
188
131
1139
1.25
1.17
5.6
3.4
6.13
6.20
ph
0.30
66
633
76
618
1.30
1.17
1.7
1.9
1.24
1.36
mg/l
0.12
57
487
34
243
1.45
1.15
2.5
2.2
0.00
0.06
estimate
—
5
54
7
32
2.21
1.08
1.6
3.9
—
—
—
0
0
22
322
0.66
1.08
1.5
1.7
—
—
—
0
0
65
524
1.30
1.07
4.8
3.8
92.07
269.42
ng/l
1.23
54
398
33
239
1.42
1.06
2.2
1.5
—
—
—
0
0
274
2608
1.33
1.05
8.3
4.8
1.40
1.43
mmol/l
0.50
257
2444
15
91
1.68
1.02
2.6
2.6
—
—
—
0
0
275
2622
1.32
1.02
8.1
4.9
4.15
4.61
mmol/l
11.80
257
2470
7
35
2.02
1.00
2.9
1.6
30.14
32.54
pg
—
7
35
15
93
1.64
0.95
1.5
1.6
—
6.16
—
0
14
16
101
1.61
0.95
2.3
2.4
157.67
6194.55
u/l
—
6
41
278
2661
1.31
0.94
8.9
5.5
2.25
2.72
mmol/l
16.85
263
2495
9
52
1.75
0.93
1.4
1.3
53.78
59.70
mmol/l
—
9
46
48
380
1.31
0.91
1.3
1.4
1152.00
533.95
titre
—
5
86
5
102
0.48
0.91
1.8
2.1
216.20
219.18
pmol/l
—
5
97
12
71
1.72
0.90
1.2
1.4
13.53
10.73
mg/l
0.28
12
66
17
111
1.56
0.89
3.9
1.8
—
—
—
0
0
31
230
1.38
0.89
1.6
1.4
—
—
—
0
0
6
30
2.02
0.87
1.2
1.2
—
—
—
0
0
20
138
1.48
0.84
2.8
2.2
—
—
—
0
0
36
278
1.33
0.82
9.4
2.6
28.77
32.69
u/l
0.47
31
233
23
313
0.71
0.80
1.4
1.5
—
—
—
0
0
68
573
1.24
0.79
3.3
2.0
—
—
—
0
0
120
1071
1.19
0.78
5.7
3.6
0.00
0.02
estimate
0.78
26
257
202
1890
1.18
0.74
3.8
3.2
55.22
47.49
u/l
0.47
189
1787
7
38
1.86
0.74
1.6
1.4
—
—
—
0
0
7
38
1.86
0.74
1.6
1.4
—
—
—
0
0
7
38
1.86
0.74
1.6
1.4
—
—
—
0
0
7
38
1.86
0.74
1.6
1.4
—
—
—
0
0
42
338
1.28
0.72
2.3
2.5
5.97
8.54
umol/l
1.26
36
295
274
2639
1.25
0.72
34.7
15.9
24.07
24.26
mg/l
0.03
242
2175
7
118
0.58
0.69
1.0
1.8
—
—
—
0
0
5
27
1.86
0.68
1.2
1.2
0.02
1.45
promille
—
5
20
5
27
1.86
0.68
1.0
1.4
91.40
38.81
ng/l
—
5
27
5
94
0.52
0.67
8.4
13.4
—
—
—
0
0
8
130
0.61
0.65
1.1
2.0
44.00
38.46
nmol/l
—
8
125
6
101
0.59
0.63
1.0
1.1
—
—
—
0
0
10
63
1.61
0.62
1.4
3.1
2.60
1.95
index
—
5
37
0
20
0.00
0.60
0.0
1.2
—
183.00
—
0
20
10
64
1.58
0.59
1.4
1.3
—
—
—
0
0
11
161
0.67
0.58
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
28
221
1.29
0.57
4.0
2.4
6.16
6.12
ph
0.06
19
151
41
343
1.22
0.53
2.5
3.1
4.82
5.10
e9/l
0.13
31
303
90
810
1.15
0.52
1.5
1.5
—
—
—
0
0
11
75
1.48
0.51
1.6
1.3
120.64
164.13
e6/l
0.14
11
56
7
106
0.65
0.49
1.9
1.1
0.87
0.92
g/l
—
7
106
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
10
70
1.44
0.42
1.3
1.2
4.60
3.63
mmol/l
—
10
64
87
794
1.13
0.41
11.2
6.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.7
—
—
—
0
0
7
103
0.67
0.40
1.9
1.1
1.49
1.48
g/l
—
7
103
11
80
1.39
0.39
1.7
1.8
—
—
—
0
0
10
135
0.73
0.37
1.4
1.5
—
—
—
0
0
11
146
0.74
0.37
1.5
1.5
—
—
—
0
0
11
145
0.75
0.35
1.4
1.5
—
—
—
0
0
11
145
0.75
0.35
1.4
1.5
—
—
—
0
0
11
145
0.75
0.35
1.4
1.5
—
—
—
0
0
112
1047
1.11
0.35
1.9
2.1
—
—
—
0
0
12
155
0.77
0.34
1.1
1.3
—
—
—
0
0
10
74
1.36
0.32
1.4
1.2
11.40
16.40
e6/l
—
10
53
7
97
0.72
0.31
1.0
1.2
—
—
—
0
0
24
279
0.85
0.28
1.3
1.5
—
—
—
0
0
10
128
0.77
0.27
1.1
1.4
27.53
19.18
iu/l
—
10
109
10
77
1.31
0.26
1.1
1.2
—
—
—
0
0
5
75
0.66
0.26
2.8
4.6
—
—
—
0
0
85
798
1.09
0.25
5.4
3.2
0.00
0.10
estimate
0.50
26
243
14
116
1.22
0.22
2.9
2.4
1.74
4.89
iu/ml
—
5
31
18
154
1.18
0.21
1.4
1.6
0.31
0.32
mg/l
—
6
69
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
5.0
—
47.10
—
0
10
0
12
0.00
0.21
0.0
1.0
—
0.22
—
0
6
0
13
0.00
0.21
0.0
1.1
—
0.21
—
0
8
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
0.00
—
0
13
10
80
1.26
0.20
1.4
1.3
566.10
464.92
mg/l
—
10
75
6
48
1.25
0.20
1.3
1.3
20.97
13.09
u/l
—
6
42
9
112
0.80
0.20
1.3
1.5
—
—
—
0
0
6
49
1.23
0.20
1.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.2
1.3
—
—
—
0
0
36
329
1.11
0.18
1.8
1.8
—
—
—
0
0
7
60
1.17
0.18
1.6
1.3
—
—
—
0
0
5
70
0.71
0.17
1.6
1.7
—
—
—
0
0
249
2527
0.94
0.16
6.8
4.9
7.96
5.93
mmol/l
14.70
229
2348
8
96
0.83
0.14
1.4
1.8
—
—
—
0
0
51
484
1.06
0.12
1.1
1.3
13.14
29.45
iu/ml
2.64
11
145
99
1020
0.96
0.11
5.2
4.9
1.95
1.94
ug/l
0.01
90
918
277
2746
1.06
0.11
27.3
13.9
—
—
—
0
0
282
2797
1.06
0.10
20.0
11.7
24.48
27.03
u/l
2.69
276
2733
58
603
0.95
0.09
2.9
3.0
0.69
0.74
ug/l
0.24
41
359
15
165
0.90
0.09
1.5
1.2
—
—
—
0
0
63
652
0.96
0.08
5.5
5.5
—
—
—
0
0
291
2894
1.05
0.07
48.2
24.1
255.99
246.72
e9/l
1.69
285
2845
33
346
0.95
0.07
1.4
1.3
—
—
—
0
0
35
365
0.95
0.06
1.1
2.6
252.13
134.55
ug/g
0.25
27
296
291
2897
1.04
0.05
48.3
24.1
7.20
6.79
e9/l
2.11
285
2844
291
2897
1.04
0.05
48.2
24.0
4.33
4.52
e12/l
6.57
285
2843
44
450
0.97
0.02
1.2
1.3
5.37
8.98
u/ml
0.36
12
180
21
209
1.01
0.00
8.0
3.7
—
—
—
0
0
32
317
1.01
0.00
1.3
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
0.65
—
0
8
0
7
0.00
-0.00
0.0
1.4
—
17.29
—
0
7
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
17.17
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
0.44
—
0
5
0
9
0.00
-0.00
0.0
5.3
—
8.89
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
60.80
—
0
5
0
6
0.00
-0.00
0.0
2.7
—
2.33
—
0
6
0
9
0.00
-0.00
0.0
2.7
—
37.11
—
0
9
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.6
—
8.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
6
64
0.94
-0.00
3.0
2.8
58.83
58.26
%
—
6
64
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
77.50
—
0
6
0
6
0.00
-0.00
0.0
3.0
—
49.50
—
0
6

Mortality – FinRegistry

Association

Association between endpoint H7_RETINALDETACHTRACTION and mortality.

Females

Parameter HR [95% CI] p-value
H7_RETINALDETACHTRACTION 1.481 [1.22, 1.8] < 0.001
Birth year 0.996 [0.99, 1.0] 0.324

During the follow-up period (1.1.1998 — 31.12.2019), 260 out of 846 females with H7_RETINALDETACHTRACTION died.

Males

Parameter HR [95% CI] p-value
H7_RETINALDETACHTRACTION 1.619 [1.36, 1.92] < 0.001
Birth year 0.99 [0.98, 1.0] 0.038

During the follow-up period (1.1.1998 — 31.12.2019), 306 out of 960 males with H7_RETINALDETACHTRACTION died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETINALDETACHTRACTION.

N-year risk Females Males
1 0.144% 0.386%
5 0.809% 1.958%
10 2.047% 5.02%
15 4.393% 9.748%
20 7.447% 17.063%

Relationships between endpoints

Index endpoint: H7_RETINALDETACHTRACTION – Traction detachment of retina

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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