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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

ICD 8 haemorrhage (epidural, subarachnoid, subduralis)

ST19_ICD8HEM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-8 852
  • Cause of death: ICD-8 852

2 out of 7 registries used, show all original rules.

153

4. Check minimum number of events

None

153

5. Include endpoints

None

153

6. Filter based on genotype QC (FinnGen only)

137

Control definitions (FinnGen only)

Control exclude
ST19_INTRACRATRAUMA

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 137 26 111
Unadjusted period prevalence (%) 0.04 0.01 0.05
Median age at first event (years) 29.64 24.32 30.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
140
Matched controls
1400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
85200
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), Without mention of open intracranial wound
+∞
154.1
118
*
85290
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), Late effect
+∞
19.2
18
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
109.1
18.0
19
*
85100
ICD-8 Finland
Cerebral laceration and contusion, Without mention of open intracranial wound
+∞
15.9
15
*
85210
ICD-8 Finland
Subarachnoid, subdural and extradural haemorrhage, following injury (without mention of cerebral laceration or contusion), With open intracranial wound
+∞
13.8
13
*
E8879
ICD-8 Finland
Other and unspecified fall
35.5
10.5
13
*
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
10.7
9.6
18
19
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
9.5
9
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
9.5
9
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
7.5
9.1
21
32
S06.0
ICD-10 Finland
Concussion
15.4
8.9
14
10
9070A
ICD-9 Finland
Late effects of injuries to the nervous system, Late effect of intracranial injury without mention of skull fracture
95.6
8.5
9
*
E8190
ICD-8 Finland
Motor vehicle traffic accident of unspecified nature, Driver of motor vehicle other than motorcycle
16.9
7.4
11
7
W19
ICD-10 Finland
Unspecified fall
4.3
7.3
20
52
80000
ICD-8 Finland
Fracture of vault of skull, Closed
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
55
723
0.61
2.16
6.7
5.3
2.90
1.93
ug/l
0.79
49
639
71
874
0.62
2.06
21.4
21.9
14.08
13.81
%
0.70
71
865
29
435
0.58
1.85
3.3
3.1
0.79
0.72
ug/l
0.17
21
267
0
49
0.00
1.72
0.0
1.5
—
—
—
0
0
83
965
0.66
1.60
4.3
4.6
1.92
1.99
mu/l
0.24
75
864
91
1033
0.66
1.48
6.7
7.1
40.56
40.30
mmol/mol
0.09
80
973
64
771
0.69
1.37
3.2
3.7
14.70
14.87
pmol/l
0.21
55
688
97
1070
0.70
1.12
5.5
6.3
2.64
2.56
mmol/l
0.37
89
988
0
31
0.00
0.97
0.0
2.4
—
126.22
—
0
23
43
339
1.39
0.96
1.8
1.7
18.81
20.56
nmol/l
0.41
37
288
10
55
1.88
0.95
1.0
1.2
—
—
—
0
0
16
103
1.62
0.92
3.8
8.9
—
—
—
0
0
93
1017
0.75
0.84
4.2
4.5
1.35
1.30
mmol/l
0.34
82
926
96
1045
0.74
0.84
4.7
5.4
1.34
1.37
mmol/l
0.28
86
957
101
1090
0.74
0.82
16.4
15.7
—
—
—
0
0
0
24
0.00
0.80
0.0
4.0
—
37.03
—
0
18
18
124
1.52
0.80
2.3
3.8
7.37
7.38
ph
0.52
11
67
24
318
0.70
0.80
2.0
3.0
—
0.25
—
0
8
49
580
0.76
0.78
6.9
6.2
0.04
0.04
e9/l
0.08
44
487
8
132
0.58
0.78
1.5
1.3
—
—
—
0
0
49
579
0.76
0.77
6.8
6.2
0.57
0.61
e9/l
0.51
43
487
108
1151
0.73
0.77
27.3
26.5
7.15
6.85
e9/l
0.71
108
1121
33
412
0.74
0.76
2.7
3.3
—
—
—
0
0
5
24
2.12
0.75
1.2
1.1
—
—
—
0
0
97
1048
0.76
0.74
4.9
5.5
4.45
4.40
mmol/l
0.21
87
972
10
60
1.72
0.74
5.5
4.4
36.85
36.87
°c
—
10
60
7
116
0.58
0.71
1.4
1.8
—
—
—
0
0
13
86
1.56
0.69
8.3
7.7
24.90
24.27
mmol/l
0.23
13
81
18
243
0.70
0.66
1.6
1.6
0.81
1.45
mg/l
0.93
13
188
6
102
0.57
0.65
1.2
1.4
—
—
—
0
0
12
79
1.57
0.65
3.9
3.5
—
—
—
0
0
8
51
1.60
0.61
2.1
2.2
—
—
—
0
0
99
1058
0.78
0.61
19.3
17.6
34.38
26.35
mg/l
1.22
86
890
49
566
0.79
0.61
4.6
4.0
0.00
0.00
estimate
—
10
115
56
637
0.80
0.61
8.2
11.1
5.25
4.24
e9/l
1.41
50
543
33
399
0.77
0.59
6.2
5.6
—
—
—
0
0
8
54
1.51
0.58
1.1
1.3
—
—
—
0
0
50
572
0.80
0.56
4.8
4.0
0.00
0.00
estimate
—
10
117
6
37
1.65
0.56
1.2
1.1
—
—
—
0
0
51
582
0.81
0.56
4.8
4.0
0.00
0.04
estimate
—
9
108
10
67
1.53
0.51
1.6
3.6
24.02
23.91
mmol/l
—
10
67
34
285
1.25
0.49
1.3
1.3
—
—
—
0
0
39
446
0.83
0.42
1.7
2.0
1.55
1.35
mmol/l
0.75
31
366
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
3.9
—
—
—
0
0
7
104
0.66
0.41
1.6
1.5
—
—
—
0
0
38
434
0.83
0.40
4.7
4.0
0.00
0.00
estimate
—
8
100
19
152
1.29
0.39
5.6
8.0
1.83
1.08
mmol/l
0.40
14
125
8
112
0.70
0.39
2.4
3.0
63.90
66.07
g/l
—
8
102
28
328
0.82
0.38
3.6
3.5
0.00
0.00
estimate
—
8
91
56
508
1.17
0.36
2.7
2.8
—
—
estimate
—
0
0
17
136
1.28
0.35
6.1
8.7
95.72
94.97
%
0.23
17
131
19
156
1.25
0.33
5.9
7.8
5.50
5.02
kpa
1.12
19
147
19
156
1.25
0.33
5.9
7.8
13.30
11.53
kpa
0.62
19
149
19
156
1.25
0.33
5.9
7.8
7.40
7.42
ph
0.74
11
88
99
1035
0.85
0.33
5.0
5.6
6.25
6.13
mmol/l
0.31
88
955
7
56
1.26
0.30
2.4
3.5
24.34
24.14
mmol/l
—
7
50
21
177
1.22
0.29
5.1
7.4
104.86
104.32
mmol/l
0.25
21
177
13
161
0.79
0.29
4.3
6.1
0.94
1.03
mmol/l
0.54
13
154
65
694
0.88
0.27
5.1
4.4
—
4629.46
—
0
13
41
451
0.87
0.27
4.0
3.6
6.25
6.16
ph
0.20
26
253
9
72
1.27
0.26
1.2
2.5
0.66
0.64
%
—
9
72
9
72
1.27
0.26
1.2
2.6
1.13
1.44
%
—
9
72
41
372
1.14
0.26
3.8
4.6
—
—
—
0
0
10
126
0.78
0.25
1.2
1.6
—
—
—
0
0
10
78
1.30
0.25
1.9
3.3
123.00
131.60
g/l
—
10
72
7
94
0.73
0.23
1.9
1.5
—
—
—
0
0
40
435
0.89
0.22
3.6
3.9
11.93
10.64
mg/mmol
0.06
30
291
18
208
0.85
0.22
1.1
1.4
2.61
2.84
g/l
0.19
11
124
5
42
1.20
0.21
16.4
13.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
3.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
21
239
0.86
0.21
3.8
3.0
581.56
567.73
mosm/kgh2o
0.11
16
207
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
91.89
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
5.1
—
77.31
—
0
13
17
146
1.19
0.20
1.2
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
19
216
0.86
0.19
1.1
1.3
0.90
1.63
u/ml
—
5
53
11
91
1.23
0.18
1.5
1.5
—
—
—
0
0
16
140
1.16
0.16
1.2
1.4
—
—
—
0
0
59
561
1.09
0.16
5.4
7.6
1.20
1.20
mmol/l
0.14
49
489
18
202
0.88
0.15
1.5
1.6
1713.57
1212.99
nmol/l
0.60
13
153
54
513
1.09
0.14
5.5
6.7
1.19
1.20
mmol/l
0.30
48
471
57
595
0.93
0.12
15.1
15.6
1.31
1.30
inr
0.03
48
486
10
115
0.86
0.11
6.2
7.2
10.49
10.92
mmol/l
—
10
108
23
248
0.91
0.10
4.7
3.8
—
0.00
—
0
5
40
420
0.93
0.10
3.0
3.4
52.11
66.93
mg/l
0.24
30
289
5
46
1.09
0.09
1.6
2.7
1.82
2.97
ratio
—
5
24
25
233
1.09
0.09
5.2
4.4
1.02
1.02
kg/l
1.15
19
150
5
48
1.04
0.09
4.2
7.5
1.08
0.95
%
—
5
40
44
422
1.06
0.08
1.9
2.1
—
—
—
0
0
32
337
0.93
0.08
4.1
4.4
7.40
7.39
ph
0.56
21
233
10
88
1.15
0.08
4.9
4.8
—
—
—
0
0
29
306
0.93
0.08
6.0
4.2
0.00
0.00
estimate
—
10
106
7
68
1.03
0.08
5.7
9.8
26.23
24.44
mmol/l
—
7
68
7
68
1.03
0.08
1.7
2.8
—
—
—
0
0
9
84
1.08
0.07
6.7
4.4
—
—
—
0
0
52
504
1.05
0.07
2.0
2.1
85.45
93.16
pmol/l
0.65
32
275
49
478
1.04
0.04
3.3
4.2
38.38
51.78
ng/l
0.40
36
365
19
180
1.06
0.04
1.3
2.0
—
—
—
0
0
38
370
1.04
0.03
2.4
2.5
—
—
—
0
0
42
430
0.97
0.03
3.3
3.2
7.95
8.18
mmol/l
0.15
37
365
13
122
1.07
0.03
1.6
1.7
—
—
—
0
0
15
146
1.03
0.00
1.5
1.3
—
—
—
0
0
32
319
1.00
0.00
3.7
6.2
—
—
—
0
0
23
233
0.98
0.00
5.5
5.8
—
—
—
0
0
29
295
0.98
0.00
3.6
3.2
—
—
—
0
0
15
148
1.02
0.00
1.5
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
4.2
7.0
2.90
1.54
%
—
5
45
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
96
0.93
-0.00
2.7
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
17.40
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.8
—
927.78
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
32.84
—
0
9
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
15.3
—
1306.78
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
1.58
—
0
6
0
8
0.00
-0.00
0.0
10.0
—
15.60
—
0
8
0
5
0.00
-0.00
0.0
2.8
—
0.32
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
11.3
—
8.81
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_ICD8HEM – ICD 8 haemorrhage (epidural, subarachnoid, subduralis)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).