Small cell lung cancer, including Hilmo

C3_SCLC_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • HLP_C3_SCLC
1236

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C34
  • Hospital discharge: ICD-9 162
  • Hospital discharge: ICD-8 162
  • Cause of death: ICD-10 C34
  • Cause of death: ICD-9 162
  • Cause of death: ICD-8 162
  • Cancer registry: Topography ICD-O-3 C34
  • Cancer registry: Morphology ICD-O-3 8041
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

1236

4. Check minimum number of events

None

1236

5. Include endpoints

1236

6. Filter based on genotype QC (FinnGen only)

1098

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE
Control conditions
not HLP_C3_SCLC

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1098 270 828
Unadjusted period prevalence (%) 0.31 0.10 0.38
Median age at first event (years) 70.91 69.07 71.51

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1134
Matched controls
11340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
58.1
307.7
278
63
A04AA01
ATC
ondansetron; systemic, rectal
49.0
307.7
293
80
C34.16
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary microcellular carcinoma
+∞
307.7
337
*
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
+∞
307.7
697
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
16.8
307.7
456
437
130
Kela drug reimbursment
Malignant tumour
+∞
307.7
647
*
H02AB02
ATC
dexamethasone; systemic
161.5
307.7
489
53
A03FA01
ATC
metoclopramide; systemic, rectal
19.1
307.7
604
638
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
12.0
307.7
459
606
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
307.7
310
*
L01CB01
ATC
etoposide; systemic
+∞
307.7
314
*
Z51.5
ICD-10 Finland
Palliative care
14.3
303.2
314
296
C34.86
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary microcellular carcinoma
+∞
287.0
263
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2786.4
253.9
236
*
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
+∞
248.3
229
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
2576.2
238.1
222
*
8041/3-C34.1
ICD-O-3
Small cell carcinoma, NOS, of upper lobe, lung
+∞
217.9
202
*
C34.36
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung microcellular carcinoma
+∞
210.1
195
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
191.2
178
*
XX3DW
NOMESCO Finland
Time consuming IT work
12.5
188.0
200
191
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
169.1
158
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
27.6
159.1
110
44
N02AA05
ATC
oxycodone; systemic
5.5
158.2
415
1071
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
1757.0
158.2
150
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
154.8
145
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
391.2
141.2
139
*
A04AA02
ATC
granisetron; systemic, transdermal
743.7
136.7
132
*
8041/3-C34.3
ICD-O-3
Small cell carcinoma, NOS, of lower lobe, lung
+∞
135.2
127
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
134.1
126
*
WF002
NOMESCO Finland
Radical radiotherapy
250.8
132.0
133
6
C34.96
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary microcellular carcinoma
+∞
130.8
123
*
L03AA13
ATC
pegfilgrastim; parenteral
667.8
123.8
120
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
123.2
116
*
JN4AD
NOMESCO Finland
Body CT examination
7.1
121.5
203
336
JN4BD
NOMESCO Finland
Extensive body CT
8.2
112.8
161
223
C34.06
ICD-10 Finland
Malignant tumor of the main bronchial microcellular carcinoma
+∞
110.2
104
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
9.4
97.5
122
143
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
998.7
95.4
92
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
986.9
94.3
91
*
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
94.1
89
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
51.5
93.4
54
11
C34.0
ICD-10 Finland
Malignant neoplasm: Main bronchus
+∞
93.0
88
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
93.0
88
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
93.0
88
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
89.8
85
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
17.5
79.4
66
40
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
75.9
72
*
C34.80
ICD-10 Finland
Malignant overall tumor of bronchus and lung without histology
+∞
70.6
67
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
12.1
70.4
72
63
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
+∞
66.3
63
*
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
104.9
63.6
69
7
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
+∞
62.0
59
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
61.0
58
*
8041/3-C34.0
ICD-O-3
Small cell carcinoma, NOS, of main bronchus
+∞
61.0
58
*
TGD00
NOMESCO Finland
Needle biopsy of lung
214.7
59.7
61
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
18.1
57.8
47
27
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
57.8
55
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
158.2
57.5
60
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
149.9
54.4
57
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.9
53.6
333
1419
R84
ICPC
Malignant neoplasm bronchus/lung
284.1
53.6
54
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
53.6
51
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
542.3
52.9
52
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
14.3
52.2
48
35
C34.2
ICD-10 Finland
Malignant neoplasm: Middle lobe, bronchus or lung
+∞
51.4
49
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.5
51.1
105
208
N02AA01
ATC
morphine; systemic, rectal
8.5
50.8
67
83
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
266.9
50.5
51
*
C34.26
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung microcellular carcinoma
+∞
50.4
48
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
96.3
50.3
55
6
WW500
NOMESCO Finland
Blood transfusion
8.1
50.2
69
90
C61
ICD-10 Finland
Malignant neoplasm of prostate
177.8
49.3
51
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.8
49.2
339
1517
GD1AD
NOMESCO Finland
Thorax CT examination
4.8
48.7
116
261
L03AA02
ATC
filgrastim; parenteral
250.3
47.4
48
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
47.2
45
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
130.6
47.2
50
*
8041/3-C34.2
ICD-O-3
Small cell carcinoma, NOS, of middle lobe, lung
+∞
46.2
44
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
45.1
43
*
A06AH03
ATC
naloxegol; oral
18.6
44.8
36
20
A98
ICPC
Health maint/preventive medicine
0.4
42.6
529
7616
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
38.8
37
*
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
+∞
37.7
36
*
1623B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Upper lobe, bronchus or lung[NEOPL MAL LOB SUPER PULMONIS,CA MICROCELLURE]
+∞
37.7
36
*
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
63.8
37.4
43
7
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
379.3
37.2
37
*
N07BA03
ATC
varenicline; oral
5.5
35.5
70
133
JN4CD
NOMESCO Finland
Very extensive body CT
9.1
34.7
43
49
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
34.6
33
*
A04AD12
ATC
aprepitant; systemic
+∞
32.4
31
*
WW200, ,
SPAT
0.2
31.9
47
2044
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
169.8
31.9
33
*
L01XX17
ATC
[U] topotecan
+∞
31.4
30
*
116
Kela drug reimbursment
Prostate cancer
+∞
31.4
30
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
31.4
30
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
29.3
28
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
28.2
27
*
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
5.6
28.1
54
100
C34.89
ICD-10 Finland
Malignant overall tumor of the bronchus and lung other or unspecified histology
+∞
27.2
26
*
Z51.0
ICD-10 Finland
Radiotherapy session
277.4
26.8
27
*
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
74.5
25.9
29
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.8
25.1
80
223
L01CE01
ATC
topotecan; systemic
+∞
25.1
24
*
H02AB06
ATC
prednisolone; systemic
1.9
24.7
551
3754
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
+∞
24.0
23
*
1625B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Lower lobe, bronchus or lung[NEOPL MAL LOBI INFERIORIS PULMONIS,CA MICROCELLURE]
+∞
24.0
23
*
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
+∞
24.0
23
*
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
127.7
23.7
25
*
WZC30
NOMESCO Finland
Teaching
2.6
23.5
152
640
115
Kela drug reimbursment
Breast cancer
+∞
23.0
22
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
23.0
22
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
23.0
22
*
R03BB04
ATC
tiotropium bromide; inhalant
2.3
22.9
212
1049
N40
ICD-10 Finland
Hyperplasia of prostate
0.4
22.6
145
2979
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.6
22.6
43
79
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.2
21.6
40
1552
A79
ICPC
Malignancy NOS
117.3
21.6
23
*
N06DA02
ATC
donepezil; oral
0.1
21.1
7
718
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.4
21.1
164
751
Z72.0
ICD-10 Finland
Tobacco use
5.5
21.0
41
77
C79.3
ICD-10 Finland
Secondary malignant neoplasm of brain and cerebral meninges
+∞
20.9
20
*
C34.09
ICD-10 Finland
Malignant tumor of the main bronchus other or unspecified histology
+∞
20.9
20
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
20.9
20
*
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
19.8
19
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
19.8
19
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
203.4
19.6
20
*
I10
ICD-10 Finland
Essential (primary) hypertension
0.6
19.6
448
6115
D38.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Respiratory organ, unspecified
35.0
18.9
24
7
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
18.8
18
*
N06DX01
ATC
memantine; oral
0.1
18.7
11
974
ZX120
NOMESCO Finland
Intravenous
2.7
18.7
103
399
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.1
18.6
83
286
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
6.1
18.3
32
54
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
53.4
18.0
21
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
53.4
18.0
21
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
53.4
18.0
21
*
L02AE02
ATC
leuprorelin; implant, parenteral
67.7
17.8
20
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
17.8
17
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
17.6
82
290
EB4VA, ,
NOMESCO Finland
0.1
17.3
6
599
C34.20
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung without histology
+∞
16.7
16
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
28.0
16.5
22
8
SFA20
NOMESCO Finland
Two-surface restoration
0.5
16.4
203
3382
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
16.4
441
3070
R04.2
ICD-10 Finland
Haemoptysis
3.1
16.3
70
236
P20
ICPC
Memory disturbance
0.3
16.3
48
1448
G04CA02
ATC
tamsulosin; oral
0.5
16.1
188
3196
SAA02
NOMESCO Finland
Basic examination of mouth
0.5
16.0
247
3855
WF090
NOMESCO Finland
Profylactic radiotherapy
+∞
15.7
15
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
15.7
15
*
TQW40, ,
SPAT
0.1
14.9
*
461
1628B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Other parts of bronchus or lung[NEOPL MAL PULMONIS LOCO MULTIPLICI,CA MICROCELLURE]
+∞
14.6
14
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
14.6
14
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
14.6
14
*
C34.15
ICD-10 Finland
Malignant tumor of the anterior, bronchial or lung other non-microcellular carcinoma
+∞
14.6
14
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.9
14.5
32
67
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
15.6
14.4
23
15
C10AA05
ATC
atorvastatin; oral
0.6
14.2
256
3863
M79.6
ICD-10 Finland
Pain in limb
0.5
14.1
162
2791
J01MA12
ATC
levofloxacin; systemic
1.8
14.0
227
1356
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
16.0
14.0
22
14
1240
FHL
Bronchoscopy
4.4
13.9
35
82
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
5.1
13.9
29
58
OAB44, ,
SPAT
0.1
13.8
5
480
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
20.3
13.8
20
10
SAA01
NOMESCO Finland
Simple examination of mouth
0.6
13.8
314
4463
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.2
13.7
13
805
SFA10
NOMESCO Finland
One-surface restoration
0.5
13.7
201
3220
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
13.7
494
3662
SFA30
NOMESCO Finland
Three-surface restoration
0.5
13.6
141
2518
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
13.6
13
*
L02BB03
ATC
bicalutamide; oral
+∞
13.6
13
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
13.6
13
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
13.6
13
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
141.6
13.5
14
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
141.6
13.5
14
*
M25.5
ICD-10 Finland
Pain in joint
0.4
13.5
80
1754
H25.1
ICD-10 Finland
Senile nuclear cataract
0.5
13.3
186
3028
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.4
13.1
94
1918
J01MA14
ATC
moxifloxacin; systemic
2.2
13.1
114
545
C10AA07
ATC
rosuvastatin; oral
0.5
13.1
133
2394
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
0.5
13.0
175
2885
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.6
12.9
238
3594
I87.1
ICD-10 Finland
Compression of vein
50.6
12.9
15
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
12.5
12
*
C34.82
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary adenocarcinoma
+∞
12.5
12
*
C34.35
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other non-microcellular carcinoma
+∞
12.5
12
*
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
20.3
12.5
18
9
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.1
12.5
26
52
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
12.4
87
378
G04CA52
ATC
tamsulosin and dutasteride; systemic
0.3
12.2
42
1180
N03AX14
ATC
levetiracetam; systemic
3.5
12.2
42
124
GEA00
NOMESCO Finland
Mediastinoscopy
18.3
12.1
18
10
EB1VA, ,
NOMESCO Finland
0.2
12.0
20
845
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
0.4
11.9
87
1769
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
11.9
152
2560
M01AH05
ATC
etoricoxib; oral
0.6
11.8
270
3880
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.0
11.7
53
185
L02BG04
ATC
letrozole; oral
65.6
11.6
13
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
11.5
11
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
11.5
11
*
C34.29
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung other or unspecified histology
+∞
11.5
11
*
C34
ICD-10 Finland
Malignant neoplasm of bronchus and lung
+∞
11.5
11
*
A04AA03
ATC
tropisetron; systemic
+∞
11.5
11
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
11.5
11
*
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
0.5
11.4
139
2381
N02BE01
ATC
paracetamol; systemic, rectal
0.6
11.3
638
7545
JN6AD
NOMESCO Finland
CT of torso and neck
11.3
11.1
20
18
ZX050
NOMESCO Finland
Stereotactic radiotherapy
43.8
10.9
13
*
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.0
10.9
116
599
G04CB02
ATC
dutasteride; oral
0.3
10.8
25
871
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.4
10.8
65
1429
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
10.8
72
1519
L17
ICPC
Foot/toe symptom/complaint
0.5
10.8
109
1984
G04CB01
ATC
finasteride; oral
0.5
10.7
82
1644
R4110, ,
SPAT
0.2
10.7
20
787
R85
ICPC
Malignant neopl respiratory other
60.6
10.6
12
*
L08
ICPC
Shoulder symptom/complaint
0.4
10.6
61
1364
D19
ICPC
Teeth/gum symptom/complaint
0.4
10.6
70
1482
Z01.2
ICD-10 Finland
Dental examination
0.5
10.5
146
2414
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
10.4
10
*
C34.81
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary epidermoid carcinoma
+∞
10.4
10
*
GEA20
NOMESCO Finland
Mediastinoscopy with excision of lesion
+∞
10.4
10
*
1622B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Main bronchus[NEOPL MAL BRONCH PRINCIP,CA MICROCELLURE]
+∞
10.4
10
*
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
10.4
10
*
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
+∞
10.4
10
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
10.4
10
*
C80.90
ICD-10 Finland
Malignant tumor without specified localization without histology
+∞
10.4
10
*
SDA02
NOMESCO Finland
Periodontal treatment, brief
0.5
10.4
101
1866
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.7
10.3
32
88
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
10.7
10.3
19
18
K02.1
ICD-10 Finland
Caries of dentine
0.6
10.3
237
3431
WZC00, ,
SPAT
0.3
10.2
22
797
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
0.3
10.1
38
1027
L15
ICPC
Knee symptom/complaint
0.5
10.0
73
1494
H02
ICPC
Hearing complaint
0.4
9.9
49
1171
SDA03
NOMESCO Finland
Periodontal treatment
0.5
9.9
119
2056
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
0.6
9.9
213
3140
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
0.6
9.8
224
3259
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.7
9.8
18
17
OAB42, ,
SPAT
0.2
9.8
18
716
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
9.8
64
1363
SDA01
NOMESCO Finland
Periodontal treatment, very brief
0.4
9.7
65
1374
K03.64
ICD-10 Finland
Dental calculus supragingival
0.4
9.7
67
1399
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.1
9.6
40
133
J01FA06
ATC
roxithromycin; oral
1.5
9.5
388
2896
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
100.9
9.4
10
*
GCA32
NOMESCO Finland
Endoscopic insertion of stent into bronch
100.9
9.4
10
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
100.9
9.4
10
*
WPB10
NOMESCO Finland
Making a convalescent care decision
17.7
9.4
14
8
WF099
NOMESCO Finland
Other radiotherapy
30.3
9.4
12
*
YX9AW, ,
NOMESCO Finland
+∞
9.4
9
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
9.4
9
*
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
+∞
9.4
9
*
1624B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Middle lobe, bronchus or lung[NEOPL MAL LOBI MEDII PULMONIS,CA MICROCELLURE]
+∞
9.4
9
*
C79.39
ICD-10 Finland
Secondary malignant tumor of the meninges, ventricle or other part of the brain
+∞
9.4
9
*
C34.91
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary epidermoid carcinoma
+∞
9.4
9
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
9.4
9
*
TGA30
NOMESCO Finland
Thoracocentesis
7.0
9.3
22
32
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
0.1
9.3
5
362
HA1AA
NOMESCO Finland
X-ray mammography
3.5
9.2
31
90
L12
ICPC
Hand/finger symptom/complaint
0.3
9.2
34
928
G30.8
ICD-10 Finland
Other Alzheimer disease
0.1
9.1
*
312
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.2
9.0
14
621
HAB40
NOMESCO Finland
Wedge excision of mammary gland
15.7
9.0
14
9
Z71.8
ICD-10 Finland
Other specified counselling
0.5
9.0
104
1824
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
18.8
8.9
13
7
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.7
8.9
49
190
SPAT1312
SPAT
General health counselling
0.5
8.9
110
1892
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.6
8.9
229
3256
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.9
8.9
21
31
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
8.8
27
74
N05CF01
ATC
zopiclone; oral
1.5
8.7
365
2727
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
4.2
8.7
23
56
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.7
417
3202
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
0.3
8.7
24
760
M17.1
ICD-10 Finland
Other primary gonarthrosis
0.5
8.6
83
1547
C10AX09
ATC
ezetimibe; oral
0.4
8.6
59
1237
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
16.4
8.6
13
8
GDC00
NOMESCO Finland
Lobectomy of lung
90.7
8.4
9
*
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
90.7
8.4
9
*
GD004
NOMESCO Finland
Palliative radiotherapy of trachea, bronchi and lungs
+∞
8.3
8
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
8.3
8
*
1623X
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Upper lobe, bronchus or lung[NEOPL MAL LOB SUPER PULMONIS,EI HIST/SYTOL DG]
+∞
8.3
8
*
C79.7
ICD-10 Finland
Secondary malignant neoplasm of adrenal gland
+∞
8.3
8
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
+∞
8.3
8
*
D82
ICPC
Teeth/gum disease
0.5
8.3
111
1872
Z01.7
ICD-10 Finland
Laboratory examination
0.4
8.3
35
897
B01AF02
ATC
apixaban; oral
0.4
8.3
51
1115
B02AA02
ATC
tranexamic acid; systemic
1.9
8.3
103
562
SPAT1053
SPAT
Memory test
0.5
8.2
70
1358
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
0.4
8.1
44
1011
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
3.7
8.0
25
69
G04BD12
ATC
mirabegron; oral
0.3
8.0
27
771
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
8.0
60
270
SPAT1325
SPAT
Vaccination
0.6
8.0
169
2527
M05BX04
ATC
denosumab; parenteral
2.5
7.9
50
208
S18
ICPC
Laceration/cut
0.6
7.8
232
3221
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.6
7.8
152
2323
GD2AT
NOMESCO Finland
Cytology of the lungs with ultrasound guidance
45.3
7.7
9
*
XX1AD
NOMESCO Finland
Other CT-examination
45.3
7.7
9
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
0.6
7.7
227
3158
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
0.4
7.7
36
884
N05AX08
ATC
risperidone; systemic
0.4
7.7
32
828
2391A
ICD-9 Finland
Neoplasm of unspecified nature, Respiratory system
7.5
7.7
17
23
H13
ICPC
Plugged feeling ear
0.5
7.7
83
1493
L13
ICPC
Hip symptom/complaint
0.5
7.6
63
1238
L28
ICPC
Limited function/disability (L)
0.5
7.6
94
1623
A97
ICPC
No disease
0.5
7.6
61
1210
A07AA02
ATC
nystatin; oral
2.2
7.6
61
283
WZC30, ,
SPAT
0.2
7.5
12
521
G04CA01
ATC
alfuzosin; oral
0.5
7.5
68
1294
SPAT1256
SPAT
Intramuscular and subcutaneous injection
0.6
7.5
204
2887
HAC20
NOMESCO Finland
Total mastectomy
80.6
7.4
8
*
J01DB01
ATC
cefalexin; oral
0.7
7.4
552
6486
H91.1
ICD-10 Finland
Presbycusis
0.3
7.4
18
608
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
7.4
136
836
N17
ICPC
Vertigo/dizziness
0.4
7.3
33
823
1629X
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Bronchus and lung, unspecified[NEOPL MAL PULMONIS LOCO ALIO/NUD,EI HIST/SYTOL DG]
+∞
7.3
7
*
5826
FHL
Lobectomy or bilobectomy
+∞
7.3
7
*
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
+∞
7.3
7
*
C38.3
ICD-10 Finland
Malignant neoplasm: Mediastinum, part unspecified
+∞
7.3
7
*
C34.14
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary macrocellular anaplastic carcinoma
+∞
7.3
7
*
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
+∞
7.3
7
*
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
7.3
7
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
7.3
7
*
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
+∞
7.3
7
*
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
+∞
7.3
7
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
15.9
7.2
11
7
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
4.3
7.2
18
42
TGC00
NOMESCO Finland
Bronchial lavation
2.9
7.2
32
111
N06DA03
ATC
rivastigmine; oral, transdermal
0.2
7.2
11
491
L82
ICD-10 Finland
Seborrhoeic keratosis
0.5
7.2
50
1045
P70
ICPC
Dementia
0.1
7.2
*
235
SCA01
NOMESCO Finland
Preventive oral health care, short
0.5
7.1
71
1313
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.6
7.1
133
2058
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.7
7.1
224
3082
I50.0
ICD-10 Finland
Congestive heart failure
0.5
7.1
51
1054
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
0.2
7.0
11
484
C09AA05
ATC
ramipril; oral
0.6
7.0
182
2608
F01.9
ICD-10 Finland
Vascular dementia, unspecified
0.0
6.9
*
205
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.9
74
383
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
13.9
6.9
11
8
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
13.9
6.9
11
8
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.6
6.9
100
1653
R42
ICD-10 Finland
Dizziness and giddiness
0.6
6.8
116
1841
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
9.4
6.8
13
14
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
0.3
6.8
22
639
C09CA01
ATC
losartan; oral
0.6
6.8
134
2046
KMAK, ,
NOMESCO Finland
0.7
6.7
201
2804
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.5
6.7
39
157
A69.2
ICD-10 Finland
Lyme disease
0.2
6.6
6
306
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
0.4
6.6
35
814
A02BA02
ATC
ranitidine; systemic
1.5
6.6
229
1637
D01BA02
ATC
terbinafine; oral
0.6
6.6
112
1776
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
8.8
6.6
13
15
M01AX05
ATC
glucosamine; oral
0.6
6.6
85
1452
C08CA01
ATC
amlodipine; oral
0.7
6.5
264
3474
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.6
6.5
123
1902
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
0.5
6.5
78
1363
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
6.2
6.5
16
26
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
0.6
6.5
132
2004
K85
ICPC
Elevated blood pressure
0.5
6.5
65
1199
I50.9
ICD-10 Finland
Heart failure, unspecified
0.6
6.4
130
1979
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.5
6.4
45
940
K05.31
ICD-10 Finland
Periodontitis pronounced
1.7
6.4
106
631
UGC02
NOMESCO Finland
Rigid bronchoscopy
70.2
6.4
7
*
L02BA01
ATC
tamoxifen; oral
70.2
6.4
7
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
0.2
6.4
9
358
C09CA06
ATC
candesartan; oral
0.6
6.4
93
1537
K80
ICPC
Cardiac arrhythmia NOS
0.3
6.3
15
512
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
0.3
6.3
21
600
C38.4
ICD-10 Finland
Malignant neoplasm: Pleura
+∞
6.3
6
*
1850A
ICD-9 Finland
Malignant neoplasm of prostate[NEOPLASMA MALIGNUM PROSTATAE]
+∞
6.3
6
*
8041/3-C34.8
ICD-O-3
Small cell carcinoma, NOS, of overlapping lesion of lung
+∞
6.3
6
*
C34.01
ICD-10 Finland
Malignant tumor of the main bronchial epidermoid carcinoma
+∞
6.3
6
*
C34.34
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or hunga macrocellular anaplastic carcinoma
+∞
6.3
6
*
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
+∞
6.3
6
*
C79.0
ICD-10 Finland
Secondary malignant neoplasm of kidney and renal pelvis
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
+∞
6.3
6
*
C34.21
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung epidermoid carcinoma
+∞
6.3
6
*
OAA41
NOMESCO Finland
Health check based on individual needs
+∞
6.3
6
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
6.3
6
*
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
6.3
6
*
1629B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Bronchus and lung, unspecified[NEOPL MAL PULMONIS LOCO ALIO/NUD,CA MICROCELLURE]
+∞
6.3
6
*
ZYC01, ,
SPAT
0.3
6.2
15
510
XG410
NOMESCO Finland
Flow-volume spirometry
2.3
6.2
47
213
A06AC01
ATC
ispaghula (psylla seeds); oral
0.6
6.2
126
1917
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
0.4
6.2
26
668
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
6.1
89
1474
U02
ICPC
Urinary frequency/urgency
0.4
6.1
35
789
SPAT1043
SPAT
Audiometry
0.4
6.1
29
706

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
291
183
21.05
307.65
1.3
1.2
—
—
—
0
0
264
416
7.97
167.77
2.1
1.4
32.34
2.91
ug/l
2.54
242
316
103
70
16.08
117.43
1.3
1.3
—
—
—
0
0
93
112
8.96
72.45
1.5
2.7
—
—
—
0
0
323
1263
3.18
61.67
4.3
2.3
0.77
0.83
mmol/l
11.94
313
1153
78
2928
0.21
44.94
1.7
2.0
1.60
1.29
mmol/l
1.09
65
2394
453
6971
0.42
44.10
6.3
7.4
41.81
40.89
mmol/mol
1.14
395
6401
487
7159
0.44
39.48
4.5
6.5
2.53
2.48
mmol/l
0.63
425
6529
462
6921
0.44
39.20
4.2
5.5
1.32
1.41
mmol/l
4.50
402
6281
469
6981
0.44
39.02
4.1
5.6
4.36
4.34
mmol/l
0.21
412
6393
447
6685
0.45
35.91
4.3
4.9
1.84
2.06
mu/l
2.65
391
5990
494
7115
0.46
35.64
4.7
5.7
6.37
6.14
mmol/l
2.48
427
6373
32
25
13.14
33.26
1.3
1.6
—
—
—
0
0
456
6646
0.48
31.91
3.8
4.7
1.44
1.27
mmol/l
4.47
396
5967
580
7744
0.49
30.63
40.6
25.0
124.92
134.25
g/l
40.05
572
7577
580
7742
0.49
30.56
40.7
25.3
37.63
39.97
%
26.10
571
7570
580
7742
0.49
30.56
40.1
24.7
30.72
30.55
pg
1.45
572
7577
580
7742
0.49
30.56
40.3
24.8
4.13
4.42
e12/l
32.08
561
7457
580
7741
0.49
30.53
40.4
24.9
255.29
234.94
e9/l
7.66
564
7492
580
7741
0.49
30.53
40.2
24.8
92.58
91.92
fl
2.64
572
7574
581
7745
0.49
30.36
40.3
24.9
7.94
6.95
e9/l
16.01
562
7462
581
7702
0.50
28.92
36.5
22.5
77.45
86.82
umol/l
7.47
570
7539
351
5416
0.49
26.43
3.6
3.9
15.48
15.08
pmol/l
1.62
302
4813
67
159
4.42
26.14
1.5
1.3
75.62
59.24
mmol/l
2.09
61
126
581
7612
0.51
26.06
32.6
21.3
4.02
4.03
mmol/l
0.27
569
7390
220
3990
0.44
25.92
1.9
2.3
88.10
92.87
pmol/l
0.78
124
2139
581
7603
0.52
25.78
32.8
21.2
137.10
139.76
mmol/l
35.30
570
7395
38
55
7.11
25.14
1.8
3.0
—
—
—
0
0
573
7502
0.52
24.92
17.8
10.6
28.05
25.09
u/l
2.06
561
7139
546
7251
0.52
24.80
24.4
15.6
—
—
—
0
0
223
3950
0.46
24.10
4.1
4.3
1.88
2.29
ug/l
1.87
193
3498
49
97
5.23
23.71
1.5
1.4
—
—
—
0
0
37
60
6.34
22.01
1.4
1.2
12.41
14.73
u/l
1.21
37
55
400
5723
0.53
21.64
36.0
22.0
331.25
331.75
g/l
0.50
393
5673
181
3358
0.45
21.47
1.8
2.3
71.11
78.15
nmol/l
2.91
157
2907
51
117
4.52
20.75
1.3
1.4
3545.11
1277.98
e6/l
1.36
45
82
376
2373
1.87
20.42
4.8
5.2
—
—
—
0
0
36
63
5.87
19.86
1.2
1.2
11.06
10.00
u/l
0.23
36
55
132
2655
0.43
18.79
1.6
1.8
17.36
19.55
nmol/l
0.97
120
2212
536
3837
1.75
18.67
9.6
3.8
10.84
12.69
umol/l
2.28
526
3604
45
104
4.46
18.15
1.3
1.4
24801.06
35473.98
e6/l
0.21
36
57
36
69
5.36
18.05
1.2
1.6
258.30
271.87
mosm/kgh2o
1.70
27
47
45
105
4.42
17.94
1.2
1.4
—
—
—
0
0
326
2039
1.84
17.79
2.2
1.7
—
—
—
0
0
385
2537
1.78
17.64
4.4
4.2
—
—
—
0
0
106
2250
0.42
16.98
2.6
3.0
0.79
0.77
ug/l
0.09
73
1584
175
3043
0.50
16.10
3.1
3.4
6.96
7.47
mmol/l
1.02
137
2542
24
13
18.83
16.04
1.0
1.0
—
—
—
0
0
529
3905
1.66
15.48
14.0
5.8
4.79
4.53
e9/l
1.38
482
3314
420
5638
0.59
15.31
35.4
20.4
14.74
13.81
%
28.22
415
5522
108
2198
0.44
15.31
3.4
3.8
—
—
—
0
0
198
3268
0.52
15.28
2.7
3.0
281.54
144.15
ug/l
5.50
182
2969
178
3009
0.52
14.70
3.0
3.5
74.19
49.80
mg/l
0.66
122
1982
185
3086
0.52
14.63
4.0
4.2
21.57
8.80
mg/mmol
1.01
117
1975
581
7168
0.61
14.53
29.7
16.9
32.38
27.74
mg/l
3.02
561
5979
271
3947
0.59
12.77
3.7
4.0
0.00
0.00
estimate
-0.00
81
829
277
4007
0.59
12.68
3.7
4.0
0.00
2.07
estimate
0.50
83
845
119
596
2.11
12.12
2.7
3.7
1.17
0.84
%
0.79
87
135
25
29
8.79
12.04
1.1
1.2
100.94
1.97
ug/l
—
20
10
283
4032
0.60
11.97
3.7
4.0
0.00
0.03
estimate
2.07
81
785
36
100
3.69
11.40
1.4
1.5
—
—
—
0
0
447
3339
1.56
11.38
5.7
5.5
8.86
9.15
%
1.07
441
3066
24
49
4.98
11.24
1.8
1.5
58.08
22.76
ng/l
1.38
24
49
34
93
3.74
11.01
1.4
1.8
73.93
29.04
u/ml
1.13
27
82
338
2383
1.60
10.97
5.1
3.2
7.40
7.40
ph
1.11
261
1735
438
3336
1.51
9.81
5.7
5.4
1.72
2.99
%
40.09
432
3064
220
3169
0.62
9.06
3.2
3.5
6.18
6.27
ph
0.62
126
1769
412
5200
0.67
9.02
4.0
4.5
—
2.94
—
0
7
107
574
1.95
9.01
2.7
3.5
0.82
0.67
%
0.33
79
135
106
578
1.92
8.51
2.7
3.7
0.23
0.05
%
0.87
75
119
209
3008
0.63
8.45
4.0
4.0
0.00
0.02
estimate
1.87
72
678
154
2344
0.60
7.79
2.5
2.3
3.27
2.85
mg/l
1.64
137
1980
85
444
1.99
7.74
4.8
3.6
—
—
—
0
0
114
1871
0.57
7.71
4.2
4.2
1.02
1.02
kg/l
0.40
90
1226
40
152
2.69
7.61
1.8
1.9
122.17
47.70
u/ml
0.37
35
116
45
182
2.53
7.57
4.0
4.6
2.82
2.57
mmol/l
0.26
34
116
457
3644
1.43
7.54
5.1
5.3
0.70
0.63
e9/l
4.50
407
3068
458
3661
1.42
7.42
5.1
5.3
0.04
0.04
e9/l
0.02
410
3086
112
653
1.79
7.29
4.5
3.6
5.37
5.16
kpa
1.50
106
616
461
3703
1.41
7.21
5.3
5.4
1.77
1.76
e9/l
0.02
415
3203
108
628
1.80
7.09
2.5
1.7
514.17
371.69
nmol/l
3.26
103
569
109
638
1.78
7.00
4.6
3.6
7.43
7.41
ph
1.50
99
530
464
3766
1.39
6.69
5.3
5.4
0.15
0.21
e9/l
12.40
414
3221
437
3518
1.39
6.59
6.0
3.7
32.03
34.86
g/l
17.76
413
3206
333
2582
1.41
6.17
5.6
2.0
2.37
2.34
mmol/l
3.15
311
2233
456
3728
1.37
6.14
7.2
5.4
1.21
1.20
mmol/l
0.52
445
3352
101
603
1.74
6.08
2.8
3.8
0.07
0.02
%
0.76
71
114
123
1869
0.62
6.01
1.7
1.8
1084.76
1138.03
nmol/l
0.28
97
1414
131
1955
0.63
5.91
1.7
1.8
434.10
24567449.76
pmol/l
1.46
109
1559
496
4132
1.36
5.84
7.5
5.7
1.21
1.21
mmol/l
0.59
426
3507
65
1131
0.55
5.32
1.3
1.3
23.86
11.78
u/ml
0.57
21
394
43
201
2.18
5.31
3.8
4.1
—
—
—
0
0
6
265
0.22
5.26
1.2
1.1
—
121.00
—
0
6
30
120
2.54
5.24
1.8
2.4
—
—
—
0
0
72
1184
0.58
4.80
1.3
1.3
121.17
39.65
iu/ml
1.17
25
353
219
1650
1.41
4.65
5.5
2.1
2.54
2.45
mmol/l
16.70
201
1442
14
401
0.34
4.26
2.0
2.0
—
—
—
0
0
92
1375
0.64
4.11
1.1
1.3
0.82
1.55
u/ml
1.63
18
366
14
35
4.04
4.10
3.6
3.3
0.86
1.06
index
0.55
14
35
176
2320
0.71
4.06
3.7
4.0
0.00
0.00
estimate
0.50
65
735
258
3198
0.75
3.97
2.8
3.3
1640.27
1889.61
ng/l
0.24
237
2782
224
2827
0.74
3.89
2.3
2.3
273.85
263.82
u/l
0.04
208
2640
90
600
1.54
3.58
4.0
4.3
—
—
—
0
0
154
2018
0.73
3.38
3.7
3.6
0.00
0.01
estimate
1.15
64
630
69
1044
0.64
3.27
1.4
1.2
—
—
—
0
0
35
184
1.93
3.27
2.0
2.5
33.03
33.63
umol/l
0.07
29
166
478
4195
1.24
3.16
12.4
19.9
1.23
1.41
inr
10.04
400
3539
40
681
0.57
3.08
1.5
1.5
—
—
—
0
0
105
747
1.45
3.08
2.0
1.6
65.25
66.35
g/l
0.86
95
664
205
1631
1.31
3.02
2.4
2.8
530.25
538.16
mosm/kgh2o
0.21
176
1422
167
2116
0.75
2.90
2.8
2.6
340.79
368.37
umol/l
1.77
145
1771
15
58
2.61
2.88
1.0
1.1
—
—
—
0
0
379
4336
0.81
2.80
5.1
3.1
103.83
51.53
u/l
5.06
351
3937
22
107
2.08
2.58
2.1
2.0
88.80
89.72
%
0.34
22
107
456
5093
0.82
2.58
4.2
4.7
35.33
3660.86
e6/l
—
9
109
21
405
0.51
2.50
1.2
1.4
—
60.99
—
0
26
208
2512
0.79
2.46
2.8
3.3
—
—
—
0
0
40
634
0.62
2.38
2.5
2.9
6.19
6.05
ph
0.40
32
466
87
1177
0.72
2.33
1.1
1.3
3.07
2.84
g/l
0.35
49
671
105
788
1.37
2.31
4.3
3.5
7.36
7.36
ph
0.10
98
516
12
274
0.43
2.30
10.2
11.4
—
—
—
0
0
23
418
0.54
2.29
2.5
2.4
—
—
—
0
0
9
213
0.42
2.20
1.0
1.1
—
—
—
0
0
7
19
3.70
2.15
1.6
1.5
1689.71
58.47
nmol/24h
—
7
19
31
509
0.60
2.15
1.7
2.2
11.41
15.28
nmol/l
2.59
24
453
0
57
0.00
2.05
0.0
1.2
—
—
—
0
0
5
148
0.33
2.00
2.0
1.8
183.80
209.28
pmol/l
—
5
139
5
11
4.56
1.94
1.0
1.0
—
—
—
0
0
143
1157
1.27
1.88
1.7
2.0
—
—
—
0
0
116
1452
0.78
1.84
2.1
2.5
11.29
12.15
umol/l
0.61
109
1320
5
12
4.18
1.82
1.0
1.2
34.00
18.00
u/l
—
5
6
20
108
1.87
1.82
3.4
2.6
5.40
4.73
e9/l
0.45
20
108
78
584
1.36
1.79
1.7
1.6
—
—
—
0
0
8
29
2.77
1.79
1.7
2.3
—
—
—
0
0
11
233
0.47
1.79
2.5
4.3
—
—
—
0
0
71
944
0.74
1.75
2.4
2.5
4.00
6.88
ug/l
3.18
60
815
135
1096
1.26
1.74
5.6
6.4
7.42
7.41
ph
0.22
87
648
108
1346
0.78
1.67
2.1
2.5
2.18
2.23
g/l
0.37
97
1222
6
19
3.17
1.66
4.0
1.9
0.59
0.61
mmol/l
—
6
19
10
209
0.47
1.59
1.4
1.3
—
—
—
0
0
134
1100
1.25
1.58
5.6
6.4
1.73
1.11
mmol/l
0.78
107
887
19
320
0.59
1.52
1.4
1.2
112.63
97.79
u/ml
—
6
118
70
905
0.76
1.45
1.2
1.3
378.95
559.45
titre
1.04
19
220
5
16
3.13
1.44
2.4
1.1
—
—
—
0
0
133
1106
1.23
1.41
5.6
6.4
10.22
11.10
kpa
1.57
122
1060
133
1106
1.23
1.41
5.6
6.4
5.10
5.07
kpa
0.09
122
1060
12
223
0.53
1.37
3.4
3.1
7.46
7.76
mmol/l
0.15
12
214
15
82
1.84
1.36
1.5
1.4
—
—
—
0
0
15
82
1.84
1.36
1.5
1.4
—
—
—
0
0
15
82
1.84
1.36
1.5
1.4
—
—
—
0
0
15
82
1.84
1.36
1.5
1.4
—
—
—
0
0
164
1399
1.20
1.36
4.0
4.1
—
—
—
0
0
0
37
0.00
1.34
0.0
1.4
—
5.33
—
0
6
74
578
1.30
1.33
4.1
3.9
—
—
—
0
0
11
54
2.05
1.33
1.3
1.2
—
—
—
0
0
0
40
0.00
1.32
0.0
1.4
—
156.60
—
0
40
326
3586
0.87
1.30
4.0
4.5
26.84
143.41
ng/l
1.61
285
2857
21
130
1.63
1.27
4.6
2.5
58.81
60.26
%
0.12
21
130
15
254
0.59
1.26
3.3
3.1
1.40
1.72
mmol/l
1.29
15
245
20
315
0.63
1.26
3.8
1.8
—
—
—
0
0
38
270
1.42
1.25
5.4
5.1
1.34
1.40
mmol/l
0.20
28
240
53
693
0.75
1.22
1.3
1.3
—
—
—
0
0
32
221
1.46
1.22
4.3
3.6
6.57
1.55
index
1.43
23
114
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
14
237
0.59
1.19
1.6
1.4
—
—
—
0
0
5
20
2.51
1.15
1.6
2.3
—
—
—
0
0
105
1244
0.83
1.07
2.3
2.6
20.94
21.91
%
0.30
98
1135
29
406
0.71
1.05
1.0
1.2
755.67
298.14
u/ml
0.48
24
375
129
1107
1.19
1.03
4.0
4.5
1.07
1.02
mmol/l
0.61
121
992
20
298
0.67
1.02
1.6
1.5
50.01
36.42
mg/l
0.57
14
250
20
298
0.67
1.02
1.5
1.5
59.38
52.82
mg/l
0.18
15
249
270
2962
0.88
1.01
3.5
3.9
35.14
129.60
e6/l
6.17
211
2168
95
795
1.21
1.00
3.3
2.2
12.50
8.49
umol/l
0.91
80
700
49
625
0.77
0.98
3.1
3.8
98.44
95.98
ng/l
0.05
42
527
0
30
0.00
0.97
0.0
1.1
—
1.51
—
0
15
0
31
0.00
0.96
0.0
1.2
—
28.20
—
0
26
0
31
0.00
0.96
0.0
1.2
—
138.65
—
0
26
234
2115
1.13
0.95
11.3
4.6
—
—
—
0
0
0
32
0.00
0.95
0.0
1.4
—
135.30
—
0
23
18
269
0.66
0.94
1.6
1.4
1.43
1.37
ratio
0.17
11
158
6
28
2.15
0.91
1.3
1.1
—
—
—
0
0
6
29
2.07
0.89
1.0
1.3
26.93
35.84
u/l
—
6
18
99
1154
0.84
0.87
2.7
2.0
2.05
1.74
%
1.75
90
1014
16
240
0.66
0.86
1.0
1.3
—
—
—
0
0
60
488
1.24
0.85
1.2
1.1
—
—
—
0
0
161
1804
0.87
0.84
3.6
4.5
166.73
431.65
ng/l
2.37
137
1568
6
111
0.54
0.83
3.0
2.5
1.21
1.18
mmol/l
—
6
111
6
113
0.53
0.83
1.0
1.2
—
—
—
0
0
6
114
0.52
0.83
3.0
2.5
4.13
4.09
mmol/l
—
6
114
6
114
0.52
0.83
3.0
2.5
104.67
105.56
mmol/l
—
6
114
73
870
0.83
0.82
2.8
2.0
80.00
65.74
e9/l
1.60
48
663
0
24
0.00
0.79
0.0
1.1
—
96.20
—
0
24
0
25
0.00
0.79
0.0
1.1
—
1797.80
—
0
25
77
650
1.20
0.78
2.3
2.2
38.84
34.66
u/l
0.25
67
513
0
27
0.00
0.77
0.0
1.3
—
23.00
—
0
18
0
28
0.00
0.76
0.0
1.1
—
3.11
—
0
12
0
28
0.00
0.76
0.0
1.1
—
20.83
—
0
6
36
459
0.78
0.76
1.1
1.3
—
—
—
0
0
36
458
0.78
0.75
1.1
1.2
—
—
—
0
0
502
4783
1.09
0.73
6.3
4.8
6.85
6.91
mmol/l
0.30
487
4554
26
345
0.75
0.73
1.5
1.3
—
—
—
0
0
247
2278
1.11
0.72
5.2
2.5
45.52
34.99
u/l
0.71
232
2122
247
2284
1.10
0.69
2.4
2.2
—
—
—
0
0
5
28
1.79
0.66
1.8
2.6
455.80
1214.75
u/ml
—
5
28
32
250
1.29
0.66
2.4
2.3
116.82
131.50
g/l
0.99
17
202
5
29
1.73
0.64
1.6
2.4
49.88
45.12
%
—
5
29
62
526
1.19
0.63
1.3
1.4
—
—
—
0
0
89
781
1.15
0.60
5.7
5.5
11.12
11.89
mmol/l
0.29
80
731
0
20
0.00
0.60
0.0
7.5
—
5.26
—
0
20
23
176
1.31
0.56
1.2
1.2
—
—
—
0
0
5
86
0.58
0.56
1.2
1.3
186.20
340.52
nmol/l
—
5
75
57
490
1.17
0.52
7.8
8.7
15.60
15.78
%
0.20
50
478
16
214
0.74
0.51
1.1
1.3
16.80
4.15
u/ml
—
6
32
22
281
0.78
0.51
1.0
1.2
—
—
—
0
0
22
280
0.78
0.50
2.2
2.5
522.54
344.18
mg/l
0.34
13
92
31
252
1.24
0.50
2.7
2.2
352.04
85.82
ug/min
1.09
16
141
22
172
1.28
0.48
1.1
1.2
—
—
—
0
0
108
979
1.11
0.47
3.0
3.2
5.77
5.84
kpa
0.25
103
943
12
85
1.42
0.47
1.3
1.2
—
—
—
0
0
56
642
0.87
0.46
1.6
1.5
—
—
—
0
0
179
1914
0.92
0.43
2.7
2.5
7.21
4.62
e6/l
1.69
169
1734
10
70
1.43
0.41
1.2
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
4.01
—
0
6
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
28
336
0.83
0.40
3.7
3.9
1.80
1.48
mmol/l
0.60
28
327
0
18
0.00
0.40
0.0
1.2
—
1.68
—
0
13
22
270
0.81
0.39
1.8
3.3
0.77
0.82
nmol/l
0.25
15
211
78
863
0.90
0.39
2.5
3.3
201.18
286.52
ng/l
1.13
71
807
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.8
2.1
58.00
54.32
umol/l
—
5
30
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
84
762
1.11
0.38
6.0
7.1
—
—
—
0
0
105
965
1.10
0.38
3.0
3.2
1.93
1.88
mmol/l
0.04
86
817
5
37
1.35
0.37
2.6
3.4
—
—
—
0
0
15
191
0.78
0.37
1.1
1.1
—
795.71
—
0
7
82
898
0.91
0.35
1.9
1.8
—
—
—
0
0
166
1760
0.93
0.34
1.3
1.3
—
—
—
0
0
15
188
0.80
0.33
3.3
3.7
31.31
28.63
mg/l
—
10
139
17
137
1.24
0.32
1.5
2.1
3.20
41.24
iu/l
—
7
63
69
629
1.10
0.31
1.3
1.5
—
—
—
0
0
11
84
1.31
0.30
1.2
1.2
1.18
1.50
nmol/l
0.78
11
76
35
308
1.14
0.28
5.3
3.4
4.26
4.36
pmol/l
0.16
30
262
30
343
0.87
0.27
1.2
1.6
—
26.90
—
0
7
49
443
1.11
0.26
1.6
2.2
10.40
11.07
g/l
0.44
41
407
5
75
0.67
0.26
3.8
3.2
39.92
43.77
mg/l
—
5
57
16
192
0.83
0.25
1.2
1.2
569.06
554.91
mg/l
0.05
16
181
9
73
1.23
0.25
1.2
1.1
—
—
—
0
0
81
869
0.93
0.25
1.5
1.4
—
—
—
0
0
235
2266
1.05
0.24
2.8
3.2
0.77
0.43
e6/l
1.28
181
1699
17
143
1.19
0.23
1.2
1.1
—
—
—
0
0
7
94
0.74
0.22
1.7
1.2
—
—
nmol/l
—
0
0
562
5715
0.97
0.21
13.8
5.5
105.03
78.26
u/l
11.34
554
5264
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
6.91
—
0
7
8
104
0.77
0.21
1.1
1.2
—
—
—
0
0
5
43
1.16
0.21
2.6
3.3
—
—
—
0
0
316
3244
0.96
0.21
2.6
2.5
—
—
estimate
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
42.54
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
254
2465
1.04
0.20
2.7
2.3
64.33
61.84
u/l
0.18
227
2251
6
49
1.23
0.20
1.2
1.1
—
—
—
0
0
6
51
1.18
0.19
3.3
1.8
87.33
95.82
umol/l
—
6
51
7
58
1.21
0.18
1.0
1.3
—
—
—
0
0
180
1739
1.04
0.18
2.2
2.1
—
—
—
0
0
105
1002
1.05
0.17
3.0
3.2
7.39
7.38
ph
0.26
54
592
264
2709
0.97
0.17
3.0
3.3
55.29
106.81
e6/l
0.79
208
2112
8
71
1.13
0.16
1.5
1.5
16.14
16.52
%
—
8
71
6
78
0.77
0.15
3.2
1.2
—
—
—
0
0
6
80
0.75
0.15
1.5
1.5
8.00
7.81
mmol/l
—
6
80
9
81
1.11
0.15
1.8
1.3
—
—
—
0
0
27
246
1.10
0.14
1.9
1.6
25.00
22.80
u/ml
—
5
44
8
98
0.82
0.13
1.0
1.0
—
—
—
0
0
134
1383
0.96
0.13
2.5
3.1
0.88
1.07
e6/l
0.42
61
777
9
106
0.85
0.13
1.4
1.2
0.51
17.68
nmol/l
—
9
100
86
827
1.04
0.12
3.0
2.7
4.20
4.40
kpa
0.48
81
789
10
116
0.86
0.12
1.0
1.2
—
—
—
0
0
312
3172
0.98
0.11
15.6
10.7
0.00
0.00
e9/l
2.15
241
2566
32
298
1.08
0.11
1.2
1.3
—
—
—
0
0
48
506
0.95
0.11
1.4
1.4
—
—
—
0
0
131
1279
1.03
0.09
2.5
3.2
2.95
1.75
e6/l
0.47
59
667
6
56
1.07
0.08
1.2
1.1
—
—
—
0
0
6
58
1.03
0.08
1.5
1.2
68.22
30.03
iu/l
—
6
47
5
63
0.79
0.08
1.0
1.4
—
—
—
0
0
8
75
1.07
0.07
1.4
1.2
—
—
—
0
0
8
76
1.05
0.07
1.3
1.8
309.63
279.43
mu/l
—
8
68
18
194
0.93
0.07
1.2
1.1
—
—
—
0
0
28
295
0.95
0.06
1.1
1.2
—
—
—
0
0
11
99
1.11
0.06
1.0
1.4
102.80
259.80
pmol/l
—
5
84
9
103
0.87
0.06
1.0
1.0
—
—
—
0
0
10
111
0.90
0.06
1.0
1.1
36.80
111.50
iu/ml
—
5
14
65
632
1.03
0.06
6.2
6.3
25.45
24.48
mmol/l
0.77
59
611
35
364
0.96
0.05
1.2
1.3
0.86
1.22
g/l
2.01
30
336
14
132
1.06
0.02
1.1
1.1
—
—
—
0
0
11
116
0.95
0.00
2.4
2.8
—
—
—
0
0
154
1542
1.00
0.00
1.5
1.6
2.17
1.40
mg/l
0.67
129
1206
20
195
1.03
0.00
1.4
1.4
302.67
307.82
ug/g
0.04
12
125
10
95
1.05
0.00
1.5
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
54
0.93
0.00
1.2
1.1
2.04
2.53
mmol/l
—
5
48
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
3.00
—
0
9
9
99
0.91
-0.00
1.3
1.8
11.49
10.16
%
—
9
99
0
5
0.00
-0.00
0.0
1.8
—
371.56
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
-0.00
1.0
1.1
—
—
—
0
0
5
52
0.96
-0.00
2.4
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
100.57
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
2.07
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
345.00
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
201.80
—
0
5
0
5
0.00
-0.00
0.0
28.8
—
0.24
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_SCLC_WIDE – Small cell lung cancer, including Hilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).