Benign neoplasm: Eye, unspecified

CD2_EYE_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D31.9&
  • Hospital discharge: ICD-9 224[8-9]|2240
  • Hospital discharge: ICD-8 22409|22402
  • Cause of death: ICD-10 D31.9&
  • Cause of death: ICD-9 224[8-9]|2240
  • Cause of death: ICD-8 22409|22402

2 out of 7 registries used, show all original rules.

177

4. Check minimum number of events

None

177

5. Include endpoints

None

177

6. Filter based on genotype QC (FinnGen only)

163

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum oculi non specificatum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 163 107 56
Unadjusted period prevalence (%) 0.03 0.04 0.03
Median age at first event (years) 57.26 55.50 60.62

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
165
Matched controls
1650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D31.9
ICD-10 Finland
Benign neoplasm: Eye, unspecified
+∞
172.7
134
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
13.2
14.4
25
22
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.4
13.8
25
45
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
128.6
11.6
12
*
2240A
ICD-9 Finland
Benign neoplasm of eye, Eyeball, except conjunctiva, cornea, retina and choroid
+∞
10.5
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
10.0
51
203
CD2S4
NOMESCO Finland
Photography of eye
58.5
9.8
11
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
29.3
8.6
11
*
2248X
ICD-9 Finland
Benign neoplasm of eye, Other specified parts of eye
+∞
8.4
8
*
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
7.3
7
*
CBA10
NOMESCO Finland
Biopsy of eyelid
21.1
7.2
10
5
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
12.8
7.2
12
10
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
6.0
6.2
16
29

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
39
212
2.10
3.68
1.4
1.4
1191.11
535.86
titre
—
9
58
22
107
2.22
2.72
2.6
1.9
1.27
1.65
g/l
0.29
22
98
8
19
4.37
2.71
1.9
2.0
—
—
—
0
0
69
492
1.69
2.70
11.7
6.4
—
—
—
0
0
22
109
2.18
2.61
1.4
1.5
—
—
—
0
0
24
126
2.06
2.46
5.4
2.9
11.02
10.27
g/l
0.28
24
117
7
17
4.25
2.38
1.3
1.3
—
—
—
0
0
6
13
4.74
2.29
1.3
2.2
39.92
31.34
%
—
6
13
86
671
1.59
2.24
16.6
12.9
0.00
0.00
e9/l
0.52
73
550
6
14
4.40
2.17
2.2
1.1
—
—
—
0
0
8
27
3.06
1.96
1.5
1.2
—
—
—
0
0
87
696
1.53
1.94
9.5
6.5
2.91
2.72
%
0.32
82
647
7
22
3.28
1.90
2.0
2.5
30.86
31.91
pg
—
7
22
32
203
1.72
1.86
1.5
1.5
—
—
—
0
0
28
171
1.77
1.86
2.0
1.6
—
—
—
0
0
9
35
2.66
1.83
1.9
1.6
—
—
—
0
0
34
221
1.68
1.81
1.9
1.7
—
—
—
0
0
8
29
2.85
1.81
1.3
1.2
—
—
—
0
0
96
797
1.49
1.71
9.9
7.3
1.21
1.22
mmol/l
0.20
84
696
63
481
1.50
1.70
1.8
1.7
19.84
20.84
nmol/l
0.19
53
393
93
771
1.47
1.65
8.8
6.5
1.70
1.86
e9/l
0.99
83
683
5
14
3.65
1.62
1.0
1.3
—
—
—
0
0
6
20
3.07
1.59
1.0
1.1
—
—
—
0
0
21
125
1.78
1.52
2.4
1.7
—
—
—
0
0
127
1130
1.54
1.52
4.2
4.6
14.93
14.97
pmol/l
0.05
116
1024
91
760
1.44
1.50
8.8
6.5
0.04
0.04
e9/l
0.15
78
653
11
52
2.20
1.48
1.3
1.4
1.14
1.12
g/l
0.08
11
52
75
606
1.44
1.47
4.2
4.3
58.57
131.09
ng/l
0.35
42
441
9
39
2.38
1.45
1.8
1.5
—
—
—
0
0
5
16
3.19
1.45
1.2
1.1
—
—
—
0
0
6
22
2.79
1.45
2.2
1.6
11.05
171.59
u/ml
—
6
22
100
856
1.43
1.40
16.4
10.7
3.45
4.05
e9/l
2.59
89
749
90
759
1.41
1.36
8.8
6.5
0.56
0.58
e9/l
0.34
77
655
9
43
2.15
1.32
1.0
1.4
—
—
—
0
0
5
18
2.83
1.29
2.0
1.8
92.00
90.27
%
—
5
18
92
784
1.39
1.28
11.0
6.8
0.19
0.18
e9/l
0.16
81
685
35
250
1.51
1.27
2.4
1.8
—
—
—
0
0
44
330
1.45
1.26
1.9
1.5
2.15
2.52
g/l
0.33
31
200
6
25
2.45
1.25
4.7
6.4
106.00
104.56
mmol/l
—
6
25
6
25
2.45
1.25
4.7
6.4
14.17
10.40
mmol/l
—
6
25
39
288
1.46
1.21
4.6
3.9
85.44
124.58
ng/l
0.29
30
224
8
38
2.16
1.20
1.0
1.4
—
—
—
0
0
27
185
1.55
1.18
3.5
3.4
1.84
1.81
%
0.05
22
168
11
58
1.96
1.15
1.1
1.1
—
—
—
0
0
22
145
1.60
1.13
1.7
1.4
—
—
—
0
0
15
89
1.75
1.12
1.4
1.3
—
—
—
0
0
9
46
2.01
1.05
1.0
1.4
—
—
—
0
0
41
314
1.41
1.04
3.5
3.2
545.84
514.23
mosm/kgh2o
0.41
36
282
5
22
2.31
1.04
1.0
1.0
—
—
—
0
0
5
22
2.31
1.04
1.2
1.2
—
—
—
0
0
5
22
2.31
1.04
1.0
1.0
—
—
—
0
0
9
47
1.97
1.04
1.0
1.4
—
—
—
0
0
9
47
1.97
1.04
1.0
1.4
—
—
—
0
0
9
47
1.97
1.04
1.0
1.4
—
—
—
0
0
34
252
1.44
1.03
2.6
3.2
2.00
2.75
e6/l
0.27
15
123
9
48
1.92
1.02
1.7
1.1
—
—
—
0
0
7
35
2.04
1.01
4.0
2.7
—
—
—
0
0
93
817
1.32
0.96
4.4
4.1
0.00
0.00
estimate
-0.00
25
179
6
28
2.18
0.92
3.0
1.2
—
—
—
0
0
20
137
1.52
0.89
2.7
3.3
77.75
73.65
e9/l
0.17
15
105
8
136
0.57
0.88
1.0
2.8
0.18
0.21
e6/l
—
8
129
93
825
1.29
0.86
4.4
4.1
59.19
8.83
estimate
0.39
26
184
93
828
1.28
0.82
4.4
4.2
0.00
0.00
estimate
-0.00
25
164
10
58
1.77
0.81
1.3
1.1
—
—
—
0
0
0
26
0.00
0.79
0.0
2.0
—
—
—
0
0
11
68
1.66
0.73
1.5
1.3
—
—
—
0
0
15
102
1.52
0.70
3.8
5.8
450.87
313.81
ng/l
0.31
15
90
145
1382
1.41
0.69
5.0
5.3
5.92
5.96
mmol/l
0.12
131
1271
5
27
1.88
0.69
1.2
1.4
—
—
—
0
0
5
27
1.88
0.69
1.2
1.5
—
—
—
0
0
56
478
1.26
0.67
14.0
7.4
—
—
—
0
0
25
191
1.36
0.66
2.8
2.1
93.68
118.92
ug/g
0.32
20
156
24
183
1.36
0.64
2.9
3.5
3.71
5.60
e9/l
0.77
19
159
26
201
1.35
0.64
1.1
1.2
—
—
—
0
0
8
49
1.66
0.63
1.8
1.5
—
—
—
0
0
67
588
1.23
0.63
2.7
2.2
—
—
—
0
0
0
20
0.00
0.61
0.0
3.8
—
3.26
—
0
20
17
123
1.43
0.61
5.0
5.2
0.00
0.23
%
—
7
31
0
21
0.00
0.60
0.0
2.0
—
—
—
0
0
6
35
1.74
0.58
2.8
1.9
—
—
—
0
0
6
36
1.69
0.57
1.0
2.7
11.83
9.54
pmol/l
—
6
36
73
652
1.21
0.57
4.0
3.7
6.12
6.20
ph
0.25
42
351
41
345
1.25
0.55
2.8
2.2
1.33
1.10
mg/l
0.32
33
276
60
530
1.21
0.51
3.3
3.1
6.12
7.45
mmol/l
1.99
52
447
140
1342
1.29
0.50
6.7
6.6
39.32
39.46
mmol/mol
0.06
129
1261
16
122
1.34
0.44
4.8
5.3
0.33
0.59
%
—
6
34
43
373
1.21
0.44
7.6
4.4
89.56
91.59
%
0.22
43
368
18
141
1.31
0.42
3.6
4.5
7.38
7.37
ph
0.33
12
94
17
132
1.32
0.42
5.0
5.0
0.86
1.00
%
—
7
40
43
375
1.20
0.42
3.3
3.9
—
0.00
—
0
6
57
632
0.85
0.41
2.1
1.9
1.32
1.36
mmol/l
0.14
45
520
0
16
0.00
0.41
0.0
1.1
—
0.21
—
0
6
0
16
0.00
0.41
0.0
1.1
—
1.66
—
0
8
76
698
1.16
0.40
11.3
13.0
1.14
1.24
inr
1.18
66
575
5
35
1.44
0.39
1.0
1.2
1.07
0.84
g/l
—
5
35
15
116
1.32
0.38
3.7
2.8
—
—
—
0
0
37
321
1.20
0.38
1.9
1.8
390.21
43173893.29
pmol/l
0.50
29
271
139
1344
1.22
0.36
5.7
5.6
1.79
1.95
mu/l
0.97
131
1232
6
43
1.41
0.35
1.0
1.2
—
—
—
0
0
16
127
1.29
0.35
1.2
1.2
—
—
—
0
0
74
685
1.15
0.34
2.5
2.1
95.43
95.68
pmol/l
0.01
45
352
16
128
1.28
0.33
5.3
3.7
—
—
—
0
0
58
529
1.15
0.33
3.6
3.5
—
—
—
0
0
32
281
1.17
0.29
2.0
1.7
1003.84
1159.98
nmol/l
0.28
20
218
9
73
1.25
0.26
6.7
8.7
—
—
—
0
0
40
364
1.13
0.23
1.3
1.2
3.56
1.54
u/ml
0.30
11
100
7
91
0.76
0.23
6.1
2.5
1.07
1.26
%
—
7
91
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
7
94
0.73
0.23
9.6
6.0
24.14
24.07
mmol/l
—
7
94
54
502
1.11
0.22
3.4
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
3.38
—
0
5
0
14
0.00
0.20
0.0
1.0
—
0.19
—
0
8
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
135
1319
1.13
0.20
4.5
4.4
1.31
1.30
mmol/l
0.07
121
1207
141
1381
1.14
0.20
5.3
5.4
4.72
4.60
mmol/l
0.67
131
1282
49
456
1.11
0.20
4.8
3.6
0.00
0.00
estimate
-0.00
17
145
18
156
1.17
0.19
1.3
1.7
—
—
—
0
0
155
1529
1.23
0.18
34.9
25.9
243.38
250.31
e9/l
0.67
155
1504
18
157
1.16
0.18
11.1
3.9
1.89
1.86
mmol/l
0.01
13
134
7
59
1.19
0.18
1.6
1.4
12.79
30.04
iu/l
—
7
49
152
1498
1.19
0.17
28.0
22.1
82.98
76.65
umol/l
1.17
152
1480
15
129
1.18
0.17
5.4
5.9
0.00
0.06
%
—
5
31
8
69
1.17
0.17
1.0
2.2
—
—
—
0
0
25
226
1.13
0.16
3.5
3.3
0.80
0.75
ug/l
0.09
18
152
75
718
1.08
0.16
9.7
6.3
1.21
1.22
mmol/l
0.28
70
662
155
1531
1.20
0.16
34.7
25.9
4.37
4.43
e12/l
0.59
155
1498
155
1531
1.20
0.16
34.7
25.8
30.28
30.34
pg
0.15
155
1517
155
1531
1.20
0.16
34.7
25.8
91.20
91.34
fl
0.13
155
1517
155
1531
1.20
0.16
35.2
26.1
38.99
40.03
%
1.34
155
1517
155
1531
1.20
0.16
34.7
25.9
6.45
6.65
e9/l
0.70
155
1499
11
129
0.84
0.15
1.5
1.6
—
—
—
0
0
15
131
1.16
0.15
13.8
6.7
—
—
—
0
0
7
90
0.77
0.15
6.0
2.5
0.64
0.63
%
—
7
90
53
502
1.08
0.14
3.8
3.1
—
—
—
0
0
155
1532
1.19
0.14
35.3
26.0
130.88
133.45
g/l
1.34
155
1516
54
514
1.08
0.13
4.4
3.9
2.53
9.02
mg/mmol
3.24
36
324
52
495
1.07
0.12
5.8
4.3
7.41
7.40
ph
0.83
35
349
144
1420
1.11
0.12
22.5
17.1
18.75
23.66
mg/l
1.13
118
1186
48
456
1.07
0.12
3.4
3.1
0.22
0.45
e6/l
0.73
30
333
143
1410
1.11
0.12
6.3
6.1
2.77
2.66
mmol/l
0.75
131
1303
44
462
0.94
0.11
4.2
4.1
0.00
0.00
estimate
-0.00
22
164
5
46
1.09
0.09
10.2
6.0
—
—
—
0
0
73
709
1.05
0.09
3.2
2.8
—
—
estimate
—
0
0
35
332
1.07
0.09
5.3
5.5
—
—
—
0
0
55
530
1.06
0.09
3.1
3.3
19.84
183.25
e6/l
0.73
36
404
5
60
0.83
0.08
1.2
2.9
—
—
—
0
0
7
68
1.03
0.08
1.7
3.4
14.14
2969.22
u/ml
—
7
59
52
502
1.05
0.08
3.6
3.2
16.65
54.72
mg/l
3.06
33
333
43
413
1.06
0.07
1.8
1.4
—
—
—
0
0
34
356
0.94
0.07
4.2
4.2
1.01
1.02
kg/l
1.80
24
229
9
83
1.09
0.07
4.8
3.9
—
—
—
0
0
45
434
1.05
0.07
5.7
4.2
—
—
—
0
0
16
172
0.92
0.06
1.6
1.9
—
—
—
0
0
144
1452
0.94
0.05
20.9
15.2
—
—
—
0
0
16
149
1.08
0.05
5.2
5.8
118.44
119.84
g/l
0.12
16
149
139
1378
1.06
0.05
5.3
5.2
1.51
1.48
mmol/l
0.27
126
1269
63
619
1.03
0.03
4.7
4.1
0.00
0.00
estimate
-0.00
19
148
20
191
1.05
0.03
1.2
1.3
—
—
—
0
0
40
410
0.97
0.03
3.4
3.1
346.71
341.27
umol/l
0.10
34
358
10
93
1.08
0.02
1.3
1.4
61.70
351.37
u/ml
—
10
84
13
136
0.95
0.00
1.4
1.5
—
—
—
0
0
18
174
1.04
0.00
7.2
5.6
7.38
7.42
ph
1.00
11
110
17
174
0.97
0.00
7.4
5.6
0.35
0.67
mmol/l
0.12
12
146
23
231
0.99
0.00
2.2
2.1
—
—
—
0
0
27
269
1.00
0.00
1.4
1.3
40.85
8.66
u/ml
—
8
96
30
299
1.00
0.00
1.4
1.3
16.86
28.61
iu/ml
1.01
14
96
12
117
1.03
0.00
1.1
1.5
—
—
—
0
0
18
177
1.02
0.00
1.3
1.3
—
—
—
0
0
60
603
0.99
0.00
4.3
4.0
6.86
66.86
e6/l
3.26
39
421
10
95
1.06
0.00
16.3
3.5
23.80
24.19
mmol/l
—
10
95
0
8
0.00
0.00
0.0
1.1
—
159.33
—
0
8
0
8
0.00
0.00
0.0
6.5
—
0.63
—
0
8
7
71
0.99
-0.00
1.4
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
4.91
—
0
5
5
50
1.00
-0.00
1.8
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
36
360
1.00
-0.00
2.5
2.7
4.88
5.12
e6/l
0.05
29
337
0
6
0.00
-0.00
0.0
1.0
—
120.67
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
183.10
—
0
5
5
50
1.00
-0.00
1.2
1.1
—
106.00
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
92
0.98
-0.00
1.4
1.2
—
—
—
0
0
7
78
0.89
-0.00
1.6
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
1.20
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
0.00
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
0.59
—
0
7
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_EYE_NOS – Benign neoplasm: Eye, unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).