age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1293 |
4. Check minimum number of eventsNone |
1293 |
5. Include endpointsNone |
1293 |
6. Filter based on genotype QC (FinnGen only) |
1150 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 5
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- H35
Similar endpoints
↥List of similar endpoints to
Macular cyst
based on the number of shared cases.
Similar with more cases:
- Degeneration of macula and posterior pole
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3939 | 2208 | 1725 |
| Only index persons | 3877 | 2177 | 1700 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 72.17 | 72.28 | 72.05 |
| Only index persons | 72.18 | 72.31 | 72.02 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1150 | 635 | 515 |
| Unadjusted period prevalence (%) | 0.23 | 0.23 | 0.24 |
| Median age at first event (years) | 72.83 | 72.22 | 73.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1202
- Matched controls
- 12020
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
15.6
317.0
306
257
H35.36
ICD-10 Finland
Macular cyst
+∞
307.7
1197
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.7
307.7
429
502
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
197.3
307.7
198
12
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
419.8
307.7
395
14
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
346.3
307.7
363
15
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
24.8
307.7
584
442
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
352.9
307.7
273
10
Z96.1
ICD-10 Finland
Presence of intraocular lens
11.3
307.7
631
1068
WX140
NOMESCO Finland
Parabulbar anesthesy
47.6
307.7
405
127
CKC12
NOMESCO Finland
Photocoagulation of retina
115.1
242.7
124
12
Z01.0
ICD-10 Finland
Examination of eyes and vision
6.8
230.1
524
1232
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
69.0
195.5
107
17
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
5.8
185.8
835
3402
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
23.4
175.9
130
62
S01ED51
ATC
timolol, combinations; ophthalmic
7.1
166.6
297
533
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
294.0
154.3
154
6
H25.1
ICD-10 Finland
Senile nuclear cataract
4.6
149.8
711
2879
XCD20
NOMESCO Finland
Photoangiography of eye
72.3
149.2
81
12
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
317.5
140.6
140
5
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.9
139.2
422
1206
XCK10
NOMESCO Finland
Photography of fundus of eye
6.1
131.7
266
533
H33.0
ICD-10 Finland
Retinal detachment with retinal break
1355.2
127.5
122
*
XCH00
NOMESCO Finland
Eye pressure measurement
8.2
120.6
173
241
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
9.5
120.0
151
179
H20.1
ICD-10 Finland
Chronic iridocyclitis
33.7
118.2
76
24
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
41.9
117.2
71
18
H26.4
ICD-10 Finland
After-cataract
5.0
114.6
303
764
CJB10
NOMESCO Finland
Laser discission of secondary cataract
5.1
103.0
252
592
S01EC01
ATC
acetazolamide; systemic
12.3
98.6
101
89
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
512.5
96.9
95
*
ZXA10
NOMESCO Finland
Bilateral
3.7
94.7
410
1465
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
5.1
92.8
221
505
H35.37
ICD-10 Finland
Macular holes
958.8
92.1
89
*
S01EC04
ATC
brinzolamide; ophthalmic
6.5
90.4
161
281
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.3
89.9
640
3091
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
87.6
83
*
WX002
NOMESCO Finland
Sedation and analgesia
3.4
81.7
415
1621
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
216.9
79.3
81
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
282.0
78.5
79
*
XCW10
NOMESCO Finland
Assessment of vision
13.8
78.2
74
57
S01EA03
ATC
apraclonidine; ophthalmic
23.4
77.0
56
25
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
774.8
75.1
73
*
S01ED01
ATC
timolol; ophthalmic
6.9
72.9
119
189
XCK00
NOMESCO Finland
Perimetry
5.1
70.2
163
361
S01EC54
ATC
brinzolamide, combinations; ophthalmic
11.5
67.3
71
65
114
Kela drug reimbursment
Glaucoma
3.9
67.2
235
712
S01EA05
ATC
brimonidine; ophthalmic
7.5
65.2
97
139
H34.8
ICD-10 Finland
Other retinal vascular occlusions
225.1
62.8
64
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
62.2
717
4220
S01EE01
ATC
latanoprost; ophthalmic
4.2
60.9
181
486
H43.1
ICD-10 Finland
Vitreous haemorrhage
12.6
60.3
60
50
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
606.8
59.2
58
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
24.9
57.8
41
17
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
56.7
54
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
202.9
56.5
58
*
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
24.3
55.8
40
17
CKD60
NOMESCO Finland
Anterior vitrectomy
14.4
54.7
50
36
S01BC03
ATC
diclofenac; ophthalmic
8.5
53.8
71
88
ZXA05
NOMESCO Finland
Left side
2.6
53.7
449
2217
H26.2
ICD-10 Finland
Complicated cataract
15.9
53.1
46
30
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
52.5
50
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
50.4
48
*
ZXA00
NOMESCO Finland
Right side
2.5
48.1
464
2427
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
4.3
47.2
131
332
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
5.3
45.8
97
197
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
18.5
44.8
36
20
XCH05
NOMESCO Finland
Eye pressure longterm registration
10.8
44.0
48
46
H40.0
ICD-10 Finland
Glaucoma suspect
3.4
43.5
178
589
F38
ICPC
Eye, Other laboratory test NEC
7.6
42.3
61
84
H36.01
ICD-10 Finland
Diabetic maculopathy
116.8
42.0
45
*
H3601, E113,
ICD-10 Finland
+∞
41.9
40
*
S01EE03
ATC
bimatoprost; ophthalmic
5.7
41.3
79
146
S01EC03
ATC
dorzolamide; ophthalmic
8.4
39.9
53
66
Z3231
NOMESCO Finland
Registered nurse
2.3
38.6
432
2365
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
35.6
34
*
S01EE05
ATC
tafluprost; ophthalmic
4.2
35.2
98
248
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
4.8
34.0
80
177
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
336.0
33.0
33
*
Z2221
NOMESCO Finland
Medical doctor
2.2
33.0
397
2213
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
10.3
31.0
35
35
S01EE04
ATC
travoprost; ophthalmic
5.7
29.3
56
103
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
8.8
28.5
36
42
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
28.4
533
3454
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3.8
28.2
90
251
ZXE00
NOMESCO Finland
One hour or less
1.9
26.6
517
3370
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
26.1
25
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
25.9
147
580
A10AA01, ,
ATC
8.1
25.2
34
43
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.5
25.1
36
49
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
7.3
25.1
37
52
CHC05
NOMESCO Finland
Iridotomy
6.0
25.1
45
78
H35.9
ICD-10 Finland
Retinal disorder, unspecified
49.4
24.4
29
6
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.0
24.3
30
34
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
8.6
24.1
31
37
F29
ICPC
Eye symptom/complaint other
2.5
24.0
173
766
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.5
23.9
163
703
Z71.8
ICD-10 Finland
Other specified counselling
1.9
23.6
445
2846
A10AB01
ATC
insulin (human); parenteral
5.9
22.9
41
71
CG2T4
NOMESCO Finland
Topography assessment of cornea
8.1
22.2
30
38
A10AA02, ,
ATC
5.9
22.1
40
70
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.7
22.0
28
33
H3600, E113,
ICD-10 Finland
+∞
21.9
21
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
81.7
21.7
24
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
223.9
21.7
22
*
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
44.2
21.5
26
6
H27.1
ICD-10 Finland
Dislocation of lens
19.3
21.3
32
17
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
34.5
21.2
27
8
CS494
NOMESCO Finland
Other visual field testing
4.0
20.9
60
155
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.7
20.8
67
188
H25.8
ICD-10 Finland
Other senile cataract
2.2
20.7
200
1001
H33.5
ICD-10 Finland
Other retinal detachments
30.6
20.6
27
9
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
20.0
171
814
A98
ICPC
Health maint/preventive medicine
5.8
19.8
1179
10800
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
106.8
19.6
21
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
19.1
109
429
H26.02
ICD-10 Finland
Presenil cataract
4.2
18.9
51
126
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
17.5
18.8
29
17
H20.8
ICD-10 Finland
Other iridocyclitis
19.1
18.7
28
15
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.3
18.1
69
216
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.5
18.1
44
100
R4110
NOMESCO Finland
Physiotherapy
1.8
17.8
389
2554
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
17.6
469
3256
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.3
17.6
46
111
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
182.6
17.6
18
*
CS2P4
NOMESCO Finland
Optic nerve head imaging
6.6
17.5
28
43
A10AB04
ATC
insulin lispro; parenteral
4.6
16.9
40
89
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.3
16.8
44
106
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
64.3
16.8
19
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
16.7
16
*
H3603, E103,
ICD-10 Finland
+∞
16.7
16
*
A10AC01
ATC
insulin (human); parenteral
2.6
16.5
97
388
H36.00
ICD-10 Finland
Diabetic background retinopathy
48.2
16.1
19
*
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
5.8
15.9
29
51
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
15.9
385
2589
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
15.7
15
*
H3601, E103,
ICD-10 Finland
+∞
15.7
15
*
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
15.7
15
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
16.3
15.3
24
15
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.7
15.2
48
133
H25.0
ICD-10 Finland
Senile incipient cataract
2.4
14.5
108
482
S01BC05
ATC
ketorolac; ophthalmic
3.1
14.3
61
205
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
22.6
14.2
20
9
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
13.6
14.2
24
18
H3600, E103,
ICD-10 Finland
+∞
13.6
13
*
1LA05, ,
NOMESCO Finland
+∞
13.6
13
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
141.5
13.5
14
*
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.4
13.2
47
141
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.5
13.1
46
137
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
12.5
12
*
H16.0
ICD-10 Finland
Corneal ulcer
2.7
12.3
68
264
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
21.5
12.0
17
8
CHD00
NOMESCO Finland
Laser trabeculoplasty
4.7
11.9
27
58
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.6
11.7
315
2150
H35.4
ICD-10 Finland
Peripheral retinal degeneration
65.6
11.6
13
*
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
65.6
11.6
13
*
H3603, E113,
ICD-10 Finland
+∞
11.5
11
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
11.5
11
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
13.8
11.5
19
14
SDA03
NOMESCO Finland
Periodontal treatment
1.5
11.3
444
3301
H26.8
ICD-10 Finland
Other specified cataract
5.2
11.3
23
45
H57.1
ICD-10 Finland
Ocular pain
2.9
11.3
52
183
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
11.2
816
6921
H18.2
ICD-10 Finland
Other corneal oedema
20.2
11.1
16
8
H44.0
ICD-10 Finland
Purulent endophthalmitis
43.7
10.9
13
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
43.7
10.9
13
*
T89
ICPC
Diabetes insulin dependent
3.2
10.9
42
133
CFW99
NOMESCO Finland
Other operation on conjunctiva
15.6
10.8
17
11
A10AE05
ATC
insulin detemir; parenteral
2.5
10.8
66
269
H40
ICD-10 Finland
Glaucoma
4.7
10.5
24
52
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
10.4
10
*
A10AB05
ATC
insulin aspart; parenteral
2.2
10.4
94
455
L17
ICPC
Foot/toe symptom/complaint
1.5
10.2
393
2898
ZX198
NOMESCO Finland
Other local administration
10.1
10.0
19
19
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
4.7
10.0
23
50
CKA10
NOMESCO Finland
Biopsy of vitreous body
40.4
10.0
12
*
A10AE04
ATC
insulin glargine; parenteral
2.0
10.0
119
639
D19
ICPC
Teeth/gum symptom/complaint
1.6
9.9
334
2388
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
16.9
9.9
15
9
Z3226
NOMESCO Finland
Physiotherapist
1.6
9.7
230
1512
D06
ICPC
Abdominal pain localized other
2.0
9.6
114
610
H21.0
ICD-10 Finland
Hyphaema
11.5
9.6
17
15
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
15.2
9.5
15
10
L12
ICPC
Hand/finger symptom/complaint
1.7
9.5
210
1356
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
9.4
9
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
9.4
9
*
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
9.4
9
*
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.8
9.4
28
75
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
8.1
9.4
20
25
S01EX03, ,
ATC
3.5
9.2
31
90
CHD99
NOMESCO Finland
Other filtering operation
11.6
9.1
16
14
Z01.7
ICD-10 Finland
Laboratory examination
1.6
9.0
205
1334
CHD35
NOMESCO Finland
Laser goniopuncture
7.5
8.9
20
27
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
18.8
8.9
13
7
S29
ICPC
Skin symptom/complaint other
1.6
8.9
265
1837
H26.3
ICD-10 Finland
Drug-induced cataract
8.0
8.9
19
24
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
6.9
8.9
21
31
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.2
8.8
35
113
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
9.6
8.8
17
18
Z71.9
ICD-10 Finland
Counselling, unspecified
2.0
8.8
103
550
E10
ICD-10 Finland
Type 1 diabetes mellitus
7.2
8.7
20
28
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
8.6
473
3718
CG2S4
NOMESCO Finland
Photography of cornea
10.1
8.5
16
16
S01BA04
ATC
prednisolone; ophthalmic
3.3
8.5
32
100
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
20.2
8.5
12
6
H40.11
ICD-10 Finland
Low pressure glaucoma
2.8
8.5
41
149
CKC20
NOMESCO Finland
Cryopexy of undetached retina
90.7
8.4
9
*
G44.2
ICD-10 Finland
Tension-type headache
1.7
8.4
148
897
U02
ICPC
Urinary frequency/urgency
1.6
8.3
199
1307
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
8.3
8
*
H3601, E116,
ICD-10 Finland
+∞
8.3
8
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.2
8.3
68
317
ZXD20
NOMESCO Finland
Day surgery
1.7
8.3
149
908
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
8.3
332
2449
Z01.2
ICD-10 Finland
Dental examination
1.4
8.2
489
3888
A91
ICPC
Abnormal result investigation NOS
2.1
8.2
80
400
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
33.6
8.1
10
*
ZXC20
NOMESCO Finland
Use of chemical agents
2.8
8.0
38
137
K02.1
ICD-10 Finland
Caries of dentine
1.4
8.0
607
5037
S21
ICPC
Skin texture symptom/complaint
1.6
7.9
199
1322
F05
ICPC
Visual disturbance other
2.5
7.7
47
192
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
6.4
7.7
19
30
H04AA01
ATC
glucagon; nasal, parenteral
6.0
7.7
20
34
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
7.7
271
1944
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
18.5
7.6
11
6
H18.1
ICD-10 Finland
Bullous keratopathy
11.9
7.6
13
11
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
7.6
322
2398
EB1AA, ,
SPAT
2.0
7.5
76
385
D01
ICPC
Abdominal pain/cramps general
1.7
7.5
139
854
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
7.5
249
1764
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
7.3
587
4885
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
7.3
7
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
7.3
7
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
7.3
7
*
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
7.0
7.0
16
23
Z5132
NOMESCO Finland
Nursing associate professional
7.0
7.0
16
23
A97
ICPC
No disease
1.5
7.0
249
1788
N17
ICPC
Vertigo/dizziness
1.6
6.9
173
1148
TCG10
NOMESCO Finland
Removal of sutures from cornea
8.3
6.8
14
17
H01.0
ICD-10 Finland
Blepharitis
2.0
6.8
74
385
EB1SA, ,
SPAT
2.2
6.7
55
257
L04AB04
ATC
adalimumab; parenteral
3.3
6.7
24
73
L04AA01
ATC
[U] ciclosporin
4.0
6.6
18
45
A23
ICPC
Risk factor NOS
1.8
6.6
97
558
J01DB01
ATC
cefalexin; oral
1.4
6.5
933
8486
SFA30
NOMESCO Finland
Three-surface restoration
1.4
6.4
463
3763
F43
ICPC
Eye, Other diagnostic procedure
2.7
6.4
32
119
R05
ICD-10 Finland
Cough
1.5
6.4
244
1773
S01FA02
ATC
scopolamine; ophthalmic
5.2
6.3
18
35
C08CA01
ATC
amlodipine; oral
1.4
6.3
514
4259
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
6.3
6
*
CK2Z4
NOMESCO Finland
Ocular fundus light imaging (OCT), angiography
+∞
6.3
6
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
6.3
6
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
6.3
6
*
H3602, E103,
ICD-10 Finland
+∞
6.3
6
*
L01
ICPC
Neck symptom/complaint
1.5
6.3
179
1224
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
26.8
6.2
8
*
K02.0
ICD-10 Finland
Caries limited to enamel
1.6
6.2
173
1175
R05
ICPC
Cough
1.4
6.2
283
2124
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
12.6
6.1
10
8
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
10.1
6.0
11
11
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.0
283
2135
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1195
11037
15.20
31.92
32.3
28.7
133.44
132.94
g/l
0.56
1181
10912
1195
11037
15.20
31.92
33.0
29.0
40.02
39.74
%
1.07
1181
10904
1195
11037
15.20
31.92
32.1
28.5
6.69
6.78
e9/l
0.71
1154
10759
1195
11037
15.20
31.92
32.1
28.5
4.43
4.40
e12/l
1.00
1155
10755
1195
11036
15.22
31.92
32.2
28.5
241.17
245.01
e9/l
1.42
1160
10795
1195
11036
15.22
31.92
32.0
28.4
91.78
91.72
fl
0.18
1181
10908
379
2170
2.09
28.66
3.7
3.1
1.10
1.27
e6/l
0.31
188
1198
40
54
7.63
28.12
1.9
2.9
792.65
1112.56
u/ml
0.53
40
54
353
1994
2.09
27.49
3.7
3.3
2.50
2.32
e6/l
0.14
158
1014
127
457
2.99
26.50
2.6
1.9
39.01
39.40
u/l
0.08
115
402
1140
10036
3.63
24.29
21.4
18.7
72.66
75.14
ml/min/173m2
4.17
1059
9395
146
618
2.55
22.20
1.3
1.4
42.13
53.57
au/ml
0.25
11
43
1158
10386
4.14
22.03
7.2
6.4
2.52
2.60
mmol/l
2.22
1068
9504
1183
10787
7.12
21.71
26.0
23.0
3.98
3.99
mmol/l
1.08
1166
10574
1182
10771
6.85
21.70
25.7
22.8
140.03
139.65
mmol/l
6.04
1166
10571
1192
10950
11.65
21.46
28.5
25.3
85.99
80.08
umol/l
3.60
1183
10815
1184
10831
7.22
21.02
15.3
13.4
24.32
25.11
u/l
1.19
1153
10481
153
681
2.43
20.85
2.6
2.6
24.01
18.82
au/ml
0.39
12
50
991
8331
2.08
20.63
26.9
23.6
13.71
13.83
%
2.00
978
8214
1134
10113
3.14
20.36
5.8
5.4
1.50
1.47
mmol/l
1.26
1048
9235
1124
9985
2.94
20.17
8.1
7.1
40.76
39.76
mmol/mol
2.87
1055
9219
1137
10177
3.17
19.83
5.9
5.5
4.50
4.53
mmol/l
0.54
1057
9364
501
3464
1.77
19.63
4.0
3.5
0.40
0.43
e6/l
0.13
343
2583
605
4428
1.74
19.27
5.1
4.3
72.18
116.19
e6/l
1.16
403
3194
1098
9706
2.52
18.74
6.3
5.5
1.99
2.02
mu/l
0.24
1023
8832
438
2990
1.73
17.43
4.9
4.3
88.35
87.28
%
0.39
433
2935
707
5527
1.68
16.61
2.4
2.2
98.27
95.11
pmol/l
0.89
348
2838
1128
10196
2.73
16.57
6.3
5.7
6.18
6.02
mmol/l
3.12
1028
9235
956
8148
1.85
16.18
29.4
24.9
330.66
331.34
g/l
1.63
951
8111
542
3996
1.65
15.68
4.2
3.6
59.18
84.17
e6/l
0.38
394
3093
958
8209
1.82
15.42
5.1
4.6
13.62
13.86
mm/h
0.19
896
7617
1129
10302
2.58
14.54
20.9
18.8
25.58
26.54
mg/l
0.44
948
8699
198
1118
1.92
14.44
2.7
2.4
31.79
40.07
u/l
1.14
164
947
83
334
2.60
13.93
1.6
1.5
0.12
22.42
iu/ml
0.57
19
60
992
8683
1.82
13.68
9.2
8.8
82.87
81.26
u/l
0.31
932
8225
589
4547
1.58
13.35
2.0
2.0
1.30
1.32
mmol/l
0.21
500
3751
944
8177
1.72
13.12
4.8
4.4
15.03
15.08
pmol/l
0.26
855
7391
645
5182
1.53
11.57
2.8
2.4
79.02
80.21
nmol/l
0.47
576
4584
614
4896
1.52
11.31
11.7
12.5
0.00
0.00
e9/l
0.00
469
3988
772
6466
1.54
11.28
10.3
9.9
4.23
4.19
e9/l
0.10
638
5609
1068
9716
1.89
10.97
4.8
4.5
1.30
1.28
mmol/l
0.39
960
8785
725
6011
1.52
10.94
4.7
4.3
0.00
0.25
estimate
0.52
114
1247
749
6262
1.52
10.79
9.0
7.6
1.21
1.21
mmol/l
0.08
677
5392
339
2394
1.58
10.76
4.3
4.2
447.78
392.12
ng/l
0.13
302
2023
74
320
2.40
10.69
1.6
1.7
—
—
—
0
0
718
5963
1.51
10.57
4.6
4.3
0.00
1.23
estimate
0.50
123
1321
709
5890
1.50
10.30
4.6
4.3
0.00
0.00
estimate
0.50
116
1284
688
5685
1.49
10.23
7.8
6.8
1.21
1.21
mmol/l
0.02
646
5233
24
56
4.35
9.61
1.1
1.1
—
—
—
0
0
644
5307
1.46
9.34
2.6
2.5
—
—
—
0
0
63
279
2.33
8.67
1.5
1.2
—
—
—
0
0
143
872
1.73
7.94
1.9
1.7
—
—
—
0
0
393
3038
1.44
7.57
3.2
2.9
354.50
349.79
umol/l
0.39
342
2646
185
1226
1.60
7.44
2.1
2.2
183.21
145.27
ug/g
0.33
150
975
471
3807
1.39
6.88
1.8
1.7
21.37
20.41
nmol/l
0.67
405
3166
193
1318
1.55
6.80
3.0
2.7
8.47
8.05
umol/l
0.11
169
1173
344
2641
1.42
6.75
3.2
3.1
2.47
2.47
mmol/l
0.36
304
2375
23
69
3.38
6.57
1.3
1.2
—
—
—
0
0
576
4847
1.36
6.41
3.6
3.0
143.70
144.22
ug/l
0.02
529
4445
139
904
1.61
6.02
9.1
9.3
94.42
93.88
%
0.91
139
897
23
74
3.15
5.91
1.3
1.1
—
—
—
0
0
513
4287
1.34
5.78
4.8
4.1
18.38
7.57
mg/mmol
2.21
328
2651
779
6928
1.35
5.75
6.1
5.4
7.02
6.76
mmol/l
2.53
739
6626
295
2262
1.40
5.70
3.5
3.5
0.75
0.80
ug/l
0.46
230
1586
261
1959
1.42
5.69
1.4
1.3
19.71
37.38
iu/ml
3.47
69
630
23
76
3.07
5.66
1.3
1.1
—
—
—
0
0
23
76
3.07
5.66
1.3
1.1
—
—
—
0
0
509
4267
1.33
5.54
4.0
3.4
7.09
7.20
mmol/l
0.22
423
3587
22
72
3.09
5.51
1.3
1.1
—
—
—
0
0
466
3861
1.34
5.48
2.2
2.2
144.36
236.90
u/l
3.46
438
3656
118
757
1.62
5.41
5.0
3.7
23.82
24.43
mmol/l
1.40
118
747
23
81
2.88
5.10
1.3
1.1
—
—
—
0
0
494
4159
1.32
5.10
3.1
3.3
1314.69
1429.32
ng/l
0.29
428
3614
101
641
1.63
4.85
4.3
3.8
1.02
1.02
ratio
0.30
91
591
632
5531
1.30
4.81
5.8
5.2
35.68
34.94
g/l
2.99
598
5182
27
110
2.49
4.57
1.4
1.3
—
—
—
0
0
705
6287
1.29
4.52
6.4
7.1
11.85
11.77
umol/l
0.05
679
6035
147
1037
1.48
4.42
5.9
3.7
108.13
93.75
ng/l
0.83
132
889
15
45
3.36
4.33
1.4
1.1
—
—
—
0
0
256
2001
1.35
4.28
1.6
1.5
2.53
2.68
g/l
0.44
133
1162
23
90
2.59
4.23
1.4
1.7
25.80
25.25
u/ml
—
5
12
503
4324
1.28
4.20
4.1
3.7
2.37
2.36
mmol/l
1.40
448
3890
283
2254
1.33
4.17
1.3
1.3
1.66
1.46
u/ml
0.07
58
595
23
91
2.56
4.15
1.3
1.1
—
—
—
0
0
44
232
1.93
4.01
1.3
1.3
—
—
—
0
0
12
27
4.48
3.94
1.0
1.0
—
—
—
0
0
35
171
2.08
3.93
1.7
1.4
134.54
163.61
au/ml
0.64
11
50
54
309
1.78
3.83
1.1
1.2
—
—
—
0
0
207
1593
1.36
3.81
2.0
1.9
—
—
—
0
0
294
2385
1.31
3.77
1.6
1.8
1.28
1.36
mg/l
0.23
235
1881
169
1261
1.40
3.75
1.2
1.4
—
—
—
0
0
53
304
1.78
3.74
1.1
1.2
—
—
—
0
0
38
196
1.97
3.71
1.7
1.3
—
18.78
—
0
5
14
39
3.62
3.70
1.0
1.1
1482.50
1454.15
miu/ml
0.03
14
39
47
261
1.83
3.68
1.2
1.4
—
—
—
0
0
47
261
1.83
3.68
1.2
1.4
—
—
—
0
0
91
604
1.55
3.67
3.0
3.4
4.21
4.41
pmol/l
1.57
74
527
9
16
5.66
3.66
10.8
11.9
5.49
5.11
mmol/l
—
9
16
20
79
2.56
3.64
1.4
1.5
—
490.00
—
0
9
203
1569
1.35
3.63
4.0
4.4
238.06
250.88
u/l
0.70
196
1480
339
2819
1.28
3.58
2.9
2.8
5.54
5.34
e6/l
0.04
308
2572
81
530
1.57
3.49
2.4
2.8
2.85
3.01
g/l
0.75
72
483
444
3835
1.25
3.37
6.4
6.0
2.51
3.24
ug/l
0.95
399
3435
59
362
1.66
3.31
1.4
1.7
0.33
0.33
mg/l
0.01
26
160
216
1708
1.32
3.30
2.0
1.9
—
—
—
0
0
69
442
1.60
3.27
1.4
1.9
2.11
7.59
iu/ml
3.06
13
105
85
572
1.52
3.25
2.3
2.7
3.58
3.70
g/l
0.34
75
524
85
572
1.52
3.25
2.3
2.7
7.36
7.49
g/l
0.29
76
524
85
572
1.52
3.25
2.3
2.7
4.25
4.19
g/l
0.16
76
525
170
1304
1.35
3.19
6.2
3.6
1.07
2.02
mmol/l
3.16
151
1139
7
11
6.39
3.18
1.1
1.2
—
—
—
0
0
203
1601
1.32
3.16
7.6
7.6
0.59
1.00
mmol/l
0.85
175
1325
126
923
1.41
3.13
3.8
3.0
58.33
61.20
ml/min/173m2
0.36
49
422
94
652
1.48
3.12
1.8
1.8
1.58
1.62
g/l
0.16
85
570
204
1613
1.32
3.12
7.7
7.6
5.05
5.12
kpa
0.54
194
1551
204
1614
1.32
3.11
7.7
7.6
12.35
12.13
kpa
0.25
193
1556
109
779
1.44
3.10
2.1
2.3
12.24
13.15
nmol/l
0.52
96
694
75
498
1.54
3.06
2.3
2.9
0.69
1.42
g/l
1.05
65
429
46
270
1.73
3.05
2.4
2.3
159.20
72.89
ug/min
0.53
20
159
726
6655
1.23
3.05
3.5
3.4
52.97
54.49
u/l
0.14
676
6171
130
963
1.39
3.03
1.5
1.6
—
—
—
0
0
12
36
3.36
3.02
3.7
2.4
0.60
0.58
mmol/l
0.24
12
36
65
419
1.58
3.02
1.2
1.3
—
—
—
0
0
21
95
2.23
2.91
3.2
2.9
21.07
30.28
mg/l
0.96
15
71
231
1880
1.28
2.84
3.7
2.7
22.28
21.99
%
0.14
220
1748
244
2001
1.28
2.82
3.6
2.6
2.15
2.27
g/l
3.18
227
1844
38
217
1.78
2.79
1.2
1.2
9.49
60.05
u/ml
—
8
25
5
6
8.36
2.75
2.8
2.0
13.90
27.08
mg/l
—
5
6
64
422
1.55
2.72
2.5
2.8
0.16
0.05
g/l
0.34
56
380
419
3666
1.22
2.69
3.6
3.3
34.08
32.93
u/l
0.16
378
3446
257
2133
1.26
2.69
3.6
2.7
12.27
12.32
umol/l
0.04
244
1995
374
3237
1.23
2.67
2.4
2.3
2.73
2.89
mg/l
0.72
311
2760
269
2248
1.25
2.65
2.1
2.0
—
—
—
0
0
12
41
2.95
2.62
1.1
1.1
—
—
—
0
0
59
387
1.55
2.58
2.5
2.9
0.00
0.00
g/l
-0.00
53
367
343
2952
1.23
2.57
2.4
2.5
—
—
—
0
0
214
1750
1.27
2.53
9.3
5.6
1.06
1.02
mmol/l
1.10
199
1612
73
508
1.47
2.43
2.5
2.8
9.55
10.46
g/l
1.21
63
457
65
442
1.50
2.43
1.1
1.0
—
—
—
0
0
355
3089
1.21
2.37
4.6
4.9
22.14
21.75
%
0.21
195
1623
179
1446
1.28
2.34
7.8
7.9
95.89
95.47
%
0.59
173
1399
47
300
1.59
2.33
1.8
1.5
—
—
—
0
0
61
414
1.50
2.31
2.5
2.8
0.00
0.00
g/l
-0.00
53
368
10
35
2.87
2.21
2.2
2.6
41.55
18.67
ug/l
—
10
29
262
3056
0.82
2.20
4.5
3.8
0.00
0.28
estimate
0.59
84
1017
17
81
2.11
2.13
1.0
1.0
0.26
0.83
u/ml
0.69
12
41
47
309
1.54
2.08
1.3
1.2
43.58
16.77
u/ml
—
5
17
33
201
1.66
2.00
1.4
1.2
—
—
—
0
0
118
925
1.31
1.96
1.5
1.4
—
—
—
0
0
44
291
1.53
1.92
1.8
1.8
3.61
5.86
mg/l
0.46
29
237
84
629
1.36
1.91
2.2
2.0
3.14
3.49
ratio
1.98
69
505
120
1504
0.78
1.91
6.1
5.2
34.96
33.18
%
0.98
74
952
18
92
1.97
1.90
1.2
1.1
—
—
—
0
0
49
333
1.49
1.89
1.7
1.6
10596.05
13803.40
e6/l
0.49
38
231
221
1876
1.22
1.87
1.3
1.3
5.31
15.21
u/ml
3.20
64
662
152
1239
1.26
1.87
2.8
2.5
65.27
68.46
e9/l
0.80
103
922
30
182
1.66
1.86
1.3
1.3
46.53
29.98
iu/l
1.11
25
151
5
12
4.18
1.82
1.0
1.1
—
—
—
0
0
251
2166
1.20
1.80
3.4
3.3
0.82
0.81
mmol/l
0.16
224
2037
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
63
456
1.40
1.77
3.4
3.1
0.32
0.37
iu/ml
0.40
28
250
81
612
1.35
1.76
1.3
1.3
248.14
214.08
u/ml
0.14
74
554
5
13
3.86
1.71
1.0
1.1
—
—
—
0
0
0
47
0.00
1.70
0.0
3.2
—
4.84
—
0
47
0
47
0.00
1.70
0.0
3.2
—
10.22
—
0
47
143
1171
1.25
1.70
3.1
3.0
64.85
66.26
g/l
1.23
130
1087
24
141
1.72
1.69
1.0
1.3
0.19
0.19
nmol/l
0.10
17
115
7
25
2.81
1.65
1.0
1.0
—
—
—
0
0
5
134
0.37
1.61
6.4
2.5
—
—
—
0
0
47
329
1.45
1.60
3.7
3.4
2.22
1.88
index
0.15
23
169
13
249
0.52
1.60
4.2
3.9
19.01
26.04
mg/l
—
8
177
7
26
2.70
1.58
1.3
1.2
—
—
—
0
0
5
15
3.34
1.52
1.2
1.8
—
—
—
0
0
23
138
1.68
1.52
1.1
1.3
—
—
—
0
0
23
139
1.67
1.49
1.9
1.5
—
—
—
0
0
50
361
1.40
1.46
1.2
1.3
—
—
—
0
0
23
140
1.66
1.45
1.2
1.3
320.25
274.16
pmol/l
0.18
16
117
7
28
2.51
1.45
1.0
1.1
—
—
—
0
0
48
346
1.40
1.42
1.4
1.4
—
—
—
0
0
27
173
1.57
1.41
1.2
1.2
268.13
276.62
u/ml
0.05
15
96
9
177
0.50
1.40
1.7
1.4
—
—
—
0
0
51
373
1.38
1.40
1.5
1.5
249.23
275.52
ug/g
0.47
30
227
7
29
2.42
1.39
1.1
1.1
—
—
—
0
0
42
297
1.43
1.39
1.3
1.3
9.10
8.44
u/ml
—
9
52
64
488
1.33
1.36
1.9
2.3
189.36
1001.01
ug/l
1.23
59
463
35
240
1.47
1.36
1.2
1.5
—
—
—
0
0
23
143
1.62
1.36
4.1
3.7
55.94
58.54
%
0.22
18
124
70
544
1.30
1.31
3.0
3.4
459.27
2716.30
u/ml
0.67
57
482
84
1043
0.79
1.29
4.0
4.0
1.22
1.23
mmol/l
0.26
75
905
58
444
1.32
1.22
2.0
1.8
3.13
3.48
mmol/l
1.64
43
323
6
26
2.31
1.18
2.0
1.3
—
—
—
0
0
12
64
1.88
1.18
3.2
1.7
—
—
—
0
0
10
50
2.01
1.16
1.0
1.1
—
—
—
0
0
25
166
1.52
1.15
1.1
1.3
—
0.43
—
0
12
5
20
2.51
1.15
1.6
1.3
—
—
—
0
0
14
80
1.76
1.13
2.1
1.4
114.94
92.85
ng/l
0.42
14
80
8
41
1.96
1.09
1.3
1.0
—
—
—
0
0
47
356
1.33
1.08
1.6
1.7
—
—
—
0
0
10
52
1.93
1.06
1.1
1.8
39.36
40.25
g/l
—
10
52
50
384
1.32
1.06
1.3
1.2
3.50
1.28
u/ml
—
7
24
234
2599
0.88
1.05
1.6
1.8
485.83
18044838.16
pmol/l
1.46
183
2117
9
46
1.96
1.03
1.2
1.1
172.74
160.01
pmol/l
—
9
46
114
967
1.20
1.03
1.9
1.7
1.53
1.56
%
0.20
100
814
7
35
2.01
1.00
1.0
1.1
—
—
—
0
0
11
61
1.81
0.98
1.1
1.1
—
—
—
0
0
22
148
1.50
0.98
4.2
3.6
—
—
—
0
0
55
434
1.28
0.97
1.4
1.3
—
—
—
0
0
7
36
1.95
0.97
1.0
1.1
—
—
—
0
0
104
884
1.19
0.94
2.5
3.1
11.51
10.68
g/l
0.50
92
809
61
752
0.80
0.93
4.0
3.6
1.87
2.18
mmol/l
0.24
41
561
249
2262
1.13
0.93
1.7
1.8
986.34
1166.59
nmol/l
2.67
176
1698
74
609
1.23
0.92
1.2
1.2
122.33
126.77
u/ml
0.03
19
230
402
3756
1.11
0.90
2.9
2.7
62.41
83.19
u/l
0.47
374
3465
6
30
2.00
0.87
1.3
1.2
113.33
109.08
%
—
6
25
36
274
1.32
0.84
1.2
1.5
—
—
—
0
0
62
508
1.23
0.83
3.6
3.7
60.70
90.16
mg/l
0.41
53
441
62
508
1.23
0.83
3.6
3.7
78.67
164.02
mg/l
0.37
51
441
17
113
1.51
0.82
1.2
1.8
5.01
4.62
mg/l
0.12
17
108
77
646
1.21
0.82
1.6
1.5
—
—
—
0
0
19
130
1.47
0.81
1.5
1.4
280.73
276.56
mosm/kgh2o
0.40
11
96
8
47
1.71
0.80
1.1
1.5
—
—
—
0
0
86
731
1.19
0.80
3.4
2.6
1.01
1.16
%
1.60
86
724
9
150
0.60
0.79
2.3
2.4
1.24
0.35
mmol/l
—
9
145
30
225
1.34
0.78
1.7
1.8
41.53
42.12
nmol/l
0.06
30
213
563
5375
1.09
0.78
2.7
2.9
—
—
estimate
—
0
0
10
161
0.62
0.75
1.5
1.4
—
—
—
0
0
10
161
0.62
0.75
1.5
1.4
—
—
—
0
0
9
54
1.67
0.74
1.0
1.3
—
—
—
0
0
9
56
1.61
0.72
1.2
1.1
—
—
—
0
0
10
159
0.63
0.72
1.5
1.4
—
—
—
0
0
119
1050
1.15
0.72
2.8
2.2
405.56
381.02
nmol/l
0.41
110
962
7
40
1.75
0.71
1.0
1.1
—
—
—
0
0
13
194
0.67
0.71
1.2
1.2
—
—
—
0
0
28
212
1.33
0.70
3.7
3.7
1.18
1.86
%
0.68
22
191
29
221
1.32
0.70
1.1
1.3
—
165.33
—
0
15
84
723
1.17
0.70
3.3
2.6
0.54
0.62
%
1.59
84
718
7
41
1.71
0.70
1.0
1.1
—
—
—
0
0
17
118
1.45
0.69
1.0
1.1
1.13
0.79
u/ml
0.21
11
64
10
156
0.64
0.67
1.5
1.4
—
—
—
0
0
7
43
1.63
0.67
1.6
1.1
—
—
—
0
0
38
304
1.26
0.65
1.5
1.2
—
—
—
0
0
10
154
0.65
0.64
1.5
1.4
—
—
—
0
0
10
154
0.65
0.64
1.5
1.4
—
—
—
0
0
33
261
1.27
0.63
2.4
1.8
3.90
26.46
iu/l
0.48
14
101
8
50
1.60
0.61
4.1
1.7
—
—
—
0
0
8
50
1.60
0.61
4.1
1.7
—
—
—
0
0
8
51
1.57
0.60
4.1
1.7
—
—
—
0
0
0
22
0.00
0.59
0.0
2.2
—
8.18
—
0
13
0
22
0.00
0.59
0.0
1.2
—
218.00
—
0
13
20
149
1.35
0.58
1.5
1.7
67.60
65.34
%
0.10
15
93
7
116
0.60
0.57
1.3
1.2
13.00
13.07
u/l
—
7
104
117
1300
0.89
0.57
4.0
3.6
—
—
—
0
0
8
54
1.48
0.57
1.3
1.0
—
—
—
0
0
16
115
1.40
0.56
3.5
3.1
16.56
11.87
index
—
9
64
14
98
1.43
0.56
1.1
1.0
390.89
287.17
ng/l
—
9
58
14
98
1.43
0.56
1.1
1.0
751.78
659.42
ng/l
—
9
55
14
98
1.43
0.56
1.1
1.0
53.56
39.10
ng/l
—
9
57
5
88
0.57
0.56
1.0
1.2
99.40
94.35
%
—
5
81
23
178
1.30
0.53
1.6
1.9
182.83
214.98
pmol/l
0.89
23
164
6
39
1.54
0.53
1.0
1.4
25.17
23.32
%
—
6
25
602
5825
1.07
0.53
19.9
17.2
1.30
1.29
inr
0.05
492
4869
21
161
1.31
0.52
1.2
1.2
267.80
237.63
miu/ml
—
5
59
118
1068
1.12
0.52
2.7
2.4
0.79
0.48
e6/l
0.49
110
1021
15
110
1.37
0.49
1.2
1.7
—
—
—
0
0
21
163
1.29
0.48
1.1
1.6
—
—
—
0
0
7
46
1.52
0.48
1.1
1.1
122.43
200.17
iu/ml
—
7
46
131
1201
1.10
0.46
11.2
7.1
11.46
10.26
mmol/l
1.13
125
1150
423
4398
0.94
0.45
4.9
4.4
0.00
0.15
estimate
0.89
82
1048
13
95
1.37
0.43
2.4
1.2
116.77
100.66
pmol/l
0.72
13
95
39
331
1.18
0.43
1.7
1.6
—
—
—
0
0
49
425
1.16
0.42
1.4
1.8
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
13
96
1.36
0.41
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
14
183
0.76
0.40
1.2
1.2
1.43
1.55
g/l
0.71
14
183
24
195
1.24
0.40
1.2
1.5
—
—
—
0
0
38
325
1.17
0.39
1.8
2.4
129.10
125.94
g/l
0.31
21
258
9
66
1.37
0.38
3.9
1.6
—
—
—
0
0
9
66
1.37
0.38
3.9
1.6
—
—
—
0
0
9
66
1.37
0.38
3.9
1.6
—
—
—
0
0
9
66
1.37
0.38
3.9
1.6
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
139
1293
1.08
0.38
1.4
1.4
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
—
10.41
—
0
16
13
169
0.77
0.37
1.2
1.6
—
—
—
0
0
159
1490
1.08
0.36
4.0
4.4
11.57
15.48
ug/l
0.18
130
1242
9
70
1.29
0.36
1.2
1.5
—
—
—
0
0
9
70
1.29
0.36
1.2
1.5
—
—
—
0
0
29
342
0.84
0.36
7.2
3.2
1.34
1.60
mmol/l
1.44
29
334
12
90
1.34
0.36
1.1
1.0
—
—
—
0
0
28
236
1.19
0.35
1.2
1.5
—
—
—
0
0
52
463
1.13
0.33
3.6
3.6
2.77
3.36
ratio
0.19
26
265
63
697
0.90
0.33
8.8
3.8
50.97
46.57
%
0.73
63
684
6
46
1.31
0.33
1.0
1.1
—
—
—
0
0
44
390
1.13
0.31
1.3
1.7
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
53
1.32
0.31
1.0
1.2
—
—
—
0
0
26
221
1.18
0.30
2.1
1.7
—
—
—
0
0
8
62
1.29
0.28
1.3
1.3
—
—
—
0
0
8
62
1.29
0.28
1.3
1.3
—
—
—
0
0
271
2611
1.05
0.27
5.1
4.6
1.02
1.02
kg/l
0.14
183
1742
12
149
0.80
0.26
1.2
1.3
294.17
350.99
u/l
0.15
12
143
55
602
0.91
0.25
1.6
1.9
2.40
1.62
ug/l
0.17
50
533
13
158
0.82
0.23
2.1
6.0
6.94
7.28
mmol/l
—
8
134
21
243
0.86
0.23
1.5
1.4
71.07
671.48
e6/l
0.70
14
190
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
—
—
—
0
0
20
173
1.16
0.21
1.7
1.4
4361.90
100900.22
e6/l
—
10
89
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
8.12
—
0
14
334
3423
0.97
0.20
4.9
4.4
0.00
0.01
estimate
0.96
111
1190
21
239
0.88
0.19
1.5
1.3
67.23
78.07
e6/l
0.06
13
174
37
337
1.10
0.19
2.0
1.6
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
146
1405
1.04
0.17
8.7
7.3
—
—
—
0
0
45
485
0.93
0.17
2.8
2.8
—
—
—
0
0
5
69
0.72
0.17
1.8
1.3
36.38
33.13
u/l
—
5
58
32
294
1.09
0.14
1.3
1.5
—
—
—
0
0
25
275
0.91
0.14
1.0
1.4
—
—
—
0
0
10
118
0.85
0.14
1.0
1.2
5.20
5.96
u/ml
—
5
49
131
1266
1.04
0.14
2.3
2.2
0.21
0.20
g/l
0.74
120
1171
13
113
1.15
0.13
3.1
1.5
—
—
—
0
0
13
113
1.15
0.13
3.1
1.5
—
—
—
0
0
13
113
1.15
0.13
3.1
1.5
—
—
—
0
0
10
86
1.16
0.11
1.2
1.3
—
—
—
0
0
10
86
1.16
0.11
1.2
1.3
—
—
—
0
0
47
494
0.95
0.10
2.7
2.0
—
—
—
0
0
114
1108
1.03
0.10
2.6
3.3
186.29
213.34
ng/l
0.36
100
1030
38
359
1.06
0.10
1.7
1.6
21.86
23.48
u/ml
—
5
65
10
114
0.88
0.09
1.2
1.1
—
1.96
—
0
39
43
451
0.95
0.09
2.0
1.9
—
—
—
0
0
6
56
1.07
0.08
1.0
3.2
174.00
211.02
u/l
—
6
56
15
136
1.10
0.08
2.9
1.7
—
—
—
0
0
6
58
1.03
0.08
1.0
1.4
—
—
—
0
0
14
127
1.10
0.08
2.9
1.7
—
—
—
0
0
7
68
1.03
0.08
1.4
1.1
8.80
21.19
u/l
—
7
62
6
71
0.84
0.07
1.0
1.5
—
—
—
0
0
6
73
0.82
0.07
1.0
1.5
—
—
—
0
0
6
75
0.80
0.07
1.0
2.1
—
—
—
0
0
32
337
0.95
0.07
2.5
3.5
0.88
0.77
nmol/l
0.38
25
279
8
76
1.05
0.07
1.1
1.2
—
—
—
0
0
8
76
1.05
0.07
1.1
1.2
—
—
—
0
0
17
157
1.08
0.07
1.3
2.1
—
—
—
0
0
9
88
1.02
0.07
1.2
1.0
—
—
—
0
0
10
89
1.12
0.07
2.2
2.2
583.00
647.67
ml
—
5
63
9
101
0.89
0.06
1.1
1.6
—
—
—
0
0
478
4747
1.01
0.06
4.2
4.2
34.63
79.96
ng/l
1.55
373
3656
21
198
1.06
0.05
1.7
1.4
8773.17
6480.79
e6/l
0.10
12
133
10
108
0.93
0.03
1.1
1.3
—
—
—
0
0
19
182
1.04
0.02
1.3
2.2
—
—
—
0
0
27
278
0.97
0.02
3.0
2.9
31.05
34.80
umol/l
0.49
22
247
11
117
0.94
0.01
1.1
1.1
—
—
—
0
0
12
126
0.95
0.00
1.1
1.2
2.40
4.40
u/ml
—
5
40
13
136
0.96
0.00
1.0
1.0
—
—
—
0
0
111
1114
1.00
0.00
2.4
2.5
6.19
7.24
ug/l
0.38
89
979
12
119
1.01
0.00
1.3
1.2
—
—
—
0
0
14
137
1.02
0.00
1.4
1.5
26.43
33.52
ng/l
0.34
14
137
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
6.21
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
362.33
265.69
mg/l
—
6
52
5
53
0.94
-0.00
1.0
1.2
—
—
—
0
0
8
82
0.98
-0.00
1.1
1.5
—
—
—
0
0
8
86
0.93
-0.00
1.3
1.2
—
—
—
0
0
33
330
1.00
-0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint MACULAR_CYST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MACULAR_CYST | 0.698 [0.53, 0.92] | 0.01 |
| Birth year | 1.001 [0.99, 1.01] | 0.778 |
During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 1473 females with MACULAR_CYST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MACULAR_CYST | 0.688 [0.5, 0.94] | 0.018 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 1084 males with MACULAR_CYST died.
Mortality risk
Mortality risk for people of age
years, who have MACULAR_CYST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.079% | 0.103% |
| 5 | 0.537% | 0.804% |
| 10 | 1.258% | 1.964% |
| 15 | 2.398% | 4.017% |
| 20 | 4.339% | 6.824% |
Relationships between endpoints
↥Index endpoint: MACULAR_CYST – Macular cyst
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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