ILD-related respiratory insufficiency

ILD_INSUFFICIENCY

respiratory failure: The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. [NCIT:C26872]

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • ILD_ENDPOINTS
7638

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

1425

6. Filter based on genotype QC (FinnGen only)

1254

Control definitions (FinnGen only)

Control conditions
not ILD_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5976 2346 3557
Only index persons 4503 1795 2708
Unadjusted period prevalence (%)
Whole population 0.09 0.07 0.10
Only index persons 0.09 0.07 0.10
Median age at first event (years)
Whole population 74.06 75.07 73.40
Only index persons 74.56 75.67 73.83

-FinnGen-

Key figures

All Female Male
Number of individuals 1254 440 814
Unadjusted period prevalence (%) 0.30 0.16 0.37
Median age at first event (years) 72.30 70.75 73.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1292
Matched controls
12920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XG410
NOMESCO Finland
Flow-volume spirometry
17.0
307.7
321
246
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
31.4
307.7
563
310
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
9181.8
307.7
808
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
6045.0
307.7
714
*
TGC00
NOMESCO Finland
Bronchial lavation
30.8
307.7
319
136
WX725
NOMESCO Finland
Noninvasive ventilation
15.4
307.7
413
382
J96.1
ICD-10 Finland
Chronic respiratory failure
73.4
307.7
594
148
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
14.1
307.7
367
354
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
23.0
307.7
276
151
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
+∞
307.7
369
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
15.5
307.7
594
672
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
25.2
307.7
312
161
WX722
NOMESCO Finland
PEEP
12.5
305.6
343
362
GD1AD
NOMESCO Finland
Thorax CT examination
10.2
285.8
382
509
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
7.8
268.5
501
974
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
56.9
234.5
133
26
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
8.3
231.5
369
597
H02AB06
ATC
prednisolone; systemic
8.6
226.7
1080
4815
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.9
216.1
841
3100
L04AA06
ATC
mycophenolic acid; systemic
22.2
195.3
148
75
XG466
NOMESCO Finland
Sleep oxymetry
12.5
187.2
197
184
R06.0
ICD-10 Finland
Dyspnoea
5.1
186.1
760
2823
284
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
186.0
174
*
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
21.3
183.1
141
74
356
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
181.7
170
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.0
175.6
586
1839
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
60.9
171.8
96
17
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
59.6
167.5
94
17
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
46.0
165.4
98
23
WX892
NOMESCO Finland
Monitored bed care
6.1
152.0
316
653
C03CA01
ATC
furosemide; systemic
4.6
150.1
877
4068
L04AX01
ATC
azathioprine; systemic
10.2
148.7
179
201
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
7.3
146.8
243
399
R03BB04
ATC
tiotropium bromide; inhalant
5.0
141.7
389
1021
WX721
NOMESCO Finland
Oxygen concentrator therapy
73.3
140.3
76
11
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.2
138.2
1032
5596
R5140
NOMESCO Finland
Monitoring the use of the aid
5.1
137.1
361
913
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.9
125.0
340
878
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.2
124.2
310
745
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
60.7
123.4
69
12
R03AC02
ATC
salbutamol; inhalant
4.2
121.4
938
5005
L04AX05
ATC
pirfenidone; oral
+∞
120.8
114
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.1
119.3
446
1461
I50.9
ICD-10 Finland
Heart failure, unspecified
3.7
107.8
492
1830
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
18.3
99.7
81
47
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
99.0
528
2150
J01MA14
ATC
moxifloxacin; systemic
4.5
96.7
282
758
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
11.6
92.3
98
91
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.8
90.9
351
1151
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
88.8
344
1129
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
87.7
337
1099
127
Kela drug reimbursment
Transplant complication
13.8
86.8
82
63
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
33.7
85.7
55
17
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.2
85.5
195
427
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.8
85.3
331
1085
J96.0
ICD-10 Finland
Acute respiratory failure
11.0
81.5
89
86
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.0
79.8
553
2561
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.0
79.2
666
3423
R28
ICPC
Limited function/disability (R)
10.4
79.2
90
92
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.2
78.6
144
257
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
21.3
78.0
59
29
L01EX09
ATC
nintedanib; oral
+∞
75.8
72
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.6
74.7
196
480
L01XE31
ATC
[U] nintedanib
+∞
73.7
70
*
Z94.2
ICD-10 Finland
Lung transplant status
261.4
73.2
74
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
748.9
72.9
71
*
J43.9
ICD-10 Finland
Emphysema, unspecified
8.3
71.4
97
125
G47.3
ICD-10 Finland
Sleep apnoea
3.0
70.2
448
1957
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
8.1
67.8
94
124
R99
ICPC
Respiratory disease other
8.5
67.6
90
113
WX704
NOMESCO Finland
Intubation
4.1
66.0
202
554
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.5
66.0
178
444
I50.0
ICD-10 Finland
Congestive heart failure
3.5
64.8
259
853
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
+∞
64.1
61
*
R02
ICPC
Shortness of breath/dyspnoea
3.1
61.6
318
1222
L04AD01
ATC
ciclosporin; systemic
10.1
61.5
71
74
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
5.3
59.5
127
260
WX720
NOMESCO Finland
Own respiration
4.8
58.9
144
331
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
58.7
432
2004
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.0
57.9
312
1225
ZX108
NOMESCO Finland
Inhalation
15.4
55.6
49
33
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
17.9
55.1
45
26
A02BC02
ATC
pantoprazole; systemic
3.0
54.7
1032
7411
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.5
53.6
754
4689
J84.0
ICD-10 Finland
Alveolar and parietoalveolar conditions
+∞
53.5
51
*
N02AA01
ATC
morphine; systemic, rectal
6.3
53.4
93
157
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
52.8
458
2284
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
6.1
52.7
95
166
WX872
NOMESCO Finland
Intensive care
4.0
52.2
160
437
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
51.1
409
1957
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.7
50.5
361
1633
P01BA02
ATC
hydroxychloroquine; oral
3.8
50.0
167
484
RK320, ,
NOMESCO Finland
12.3
49.9
50
42
L04AD02
ATC
tacrolimus; systemic
13.5
49.6
47
36
R03AK08
ATC
formoterol and beclometasone; inhalant
5.1
49.2
109
230
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.4
48.4
509
2749
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
108.3
48.1
52
5
R04.2
ICD-10 Finland
Haemoptysis
4.7
48.1
118
271
J01MA12
ATC
levofloxacin; systemic
2.5
47.6
392
1892
GX1K5
NOMESCO Finland
Diffusion capacity
17.8
46.4
38
22
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.6
46.3
92
176
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.9
45.9
146
408
M05BA04
ATC
alendronic acid; oral
3.2
45.5
203
707
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.1
45.3
133
351
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.3
45.2
124
311
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.2
44.5
127
328
J47
ICD-10 Finland
Bronchiectasis
6.2
42.8
75
127
WX882
NOMESCO Finland
High dependency care
5.1
42.0
92
192
Z51.5
ICD-10 Finland
Palliative care
2.8
40.5
244
1001
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.4
40.4
347
1690
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
40.2
513
2955
GX2D5
NOMESCO Finland
Sleep oximetry
16.6
40.2
34
21
XJC10
NOMESCO Finland
Oesophageal pH monitoring
15.8
39.2
34
22
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
10.6
38.8
43
42
C03DA01
ATC
spironolactone; oral
2.6
38.6
282
1271
J96.9
ICD-10 Finland
Respiratory failure, unspecified
10.3
38.2
43
43
L04AA13
ATC
[U] leflunomide
6.2
37.9
66
111
R4110
NOMESCO Finland
Physiotherapy
2.2
37.7
463
2612
RK110, ,
NOMESCO Finland
10.8
37.7
41
39
XG460
NOMESCO Finland
Short time oxymetry
6.3
37.3
64
106
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
37.2
266
1185
WX726
NOMESCO Finland
High-flow oxygen therapy
72.1
37.2
42
6
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.3
37.1
100
247
A07AA02
ATC
nystatin; oral
3.5
37.0
138
428
SPAT1262
SPAT
Handing over of treatment supplies
2.3
36.5
339
1700
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.2
36.2
161
557
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.2
36.0
99
248
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.5
35.9
134
416
R03BA08
ATC
ciclesonide; inhalant
3.2
35.6
156
534
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
5.6
35.5
69
129
R03AK07
ATC
formoterol and budesonide; inhalant
2.4
35.3
303
1466
L01BA01
ATC
methotrexate; systemic
4.8
35.2
83
184
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.1
34.4
506
3038
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
3.6
34.4
121
361
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
5.1
34.3
74
152
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.6
34.3
67
126
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
33.9
317
1588
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.7
33.8
207
852
C07AB07
ATC
bisoprolol; oral
2.1
33.8
837
6057
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
7.3
33.7
50
71
ZX120
NOMESCO Finland
Intravenous
2.8
33.5
189
745
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.9
32.9
102
279
N02AX02
ATC
tramadol; systemic, rectal
2.0
32.7
665
4464
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.2
32.3
140
476
Z2446
NOMESCO Finland
Social worker
3.3
31.9
128
415
XX4BW, ,
NOMESCO Finland
89.9
31.9
35
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.1
31.4
141
489
5150X
ICD-9 Finland
Postinflammatory pulmonary fibrosis[FIBROSIS PULMONUM E CAUSA IGNOTA]
+∞
31.4
30
*
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
4.8
31.4
72
156
B01AA03
ATC
warfarin; systemic
2.1
31.3
420
2419
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
9.7
30.7
36
38
H02AB07
ATC
prednisone; oral
2.4
30.7
244
1134
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.1
30.4
139
487
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
59.9
30.2
35
6
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
42.2
30.0
37
9
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
29.6
247
1171
J01AA02
ATC
doxycycline; systemic
2.3
29.5
1040
8357
R03BA05
ATC
fluticasone; inhalant
2.3
29.0
268
1327
WW200
NOMESCO Finland
Immunization
5.0
28.8
63
131
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
28.6
171
692
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.1
28.4
128
444
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
27.7
137
501
R05
ICD-10 Finland
Cough
2.1
27.3
318
1723
GD2SN
NOMESCO Finland
Lung ventilation SPECT
8.9
27.3
34
39
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
27.2
118
400
Z3226
NOMESCO Finland
Physiotherapist
2.2
27.1
299
1586
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
27.0
396
2333
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
26.9
300
1597
WX702
NOMESCO Finland
Supraglottic ventilation device
3.3
26.9
105
334
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
6.9
26.9
42
63
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.2
26.2
107
350
D86.0
ICD-10 Finland
Sarcoidosis of lung
7.6
26.0
37
50
J01FA06
ATC
roxithromycin; oral
1.9
25.7
542
3592
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
25.6
181
793
JN4AD
NOMESCO Finland
Body CT examination
2.3
25.6
232
1135
GX1D5
NOMESCO Finland
Flow volume spirometry
30.7
25.1
33
11
C01DA14
ATC
isosorbide mononitrate; oral
2.0
25.0
355
2059
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.7
25.0
81
228
SPAT1263
SPAT
Sampling
1.8
24.4
579
3963
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
8.0
24.3
33
42
GD1UN
NOMESCO Finland
Lung circulation SPECT
9.2
23.9
29
32
R81
ICPC
Pneumonia
3.4
23.6
87
267
L04AA01
ATC
[U] ciclosporin
7.0
23.4
36
53
WX730
NOMESCO Finland
Conventional respirator
5.4
23.4
46
87
I27.0
ICD-10 Finland
Primary pulmonary hypertension
26.4
22.7
31
12
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.0
22.7
66
172
L04AX03
ATC
methotrexate; systemic
2.6
22.6
146
612
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.1
22.2
99
341
A28
ICPC
Limited function/disability NOS
1.9
22.1
365
2215
A07EC01
ATC
sulfasalazine; oral, rectal
2.7
21.9
124
486
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.1
21.7
46
93
R03BA01
ATC
beclometasone; inhalant
2.2
21.6
211
1060
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.7
21.3
125
499
XX9XE
NOMESCO Finland
Other ultrasound examination
9.1
21.2
26
29
L88
ICPC
Rheumatoid/seropositive arthritis
3.6
21.2
72
209
A10AC01
ATC
insulin (human); parenteral
2.5
21.1
141
600
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
8.6
21.1
27
32
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.4
20.9
78
241
J01FF01
ATC
clindamycin; systemic
1.8
20.8
387
2433
A02BC01
ATC
omeprazole; systemic
1.8
20.4
402
2568
Z3231
NOMESCO Finland
Registered nurse
1.8
20.4
401
2561
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
20.4
200
1005
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.7
20.1
65
183
XF622
NOMESCO Finland
Measurement of minute volume of heart
23.8
20.0
28
12
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.1
19.8
42
85
N03AX16
ATC
[U] pregabalin
1.9
19.6
335
2044
C02KX04
ATC
macitentan; oral
106.7
19.6
21
*
J01FA10
ATC
azithromycin; systemic
1.7
19.6
616
4484
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.5
19.6
38
71
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.4
19.6
141
621
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.0
19.1
41
84
A02BC05
ATC
esomeprazole; systemic
1.7
19.0
537
3788
R03BB01
ATC
ipratropium bromide; inhalant
2.9
18.9
94
344
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.8
18.9
384
2467
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.4
18.9
141
631
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
18.7
102
392
A10AB05
ATC
insulin aspart; parenteral
2.4
18.6
140
628
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
39.0
18.6
23
6
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.2
18.5
49
119
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
18.5
578
4182
GX2C5
NOMESCO Finland
Short-lasting oximetry
13.8
18.3
31
23
Z2221
NOMESCO Finland
Medical doctor
1.8
18.3
364
2321
R95
ICPC
Chron obstructive pulmonary disease
3.1
18.2
80
273
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
33.4
18.0
23
7
J01CA04
ATC
amoxicillin; systemic
1.8
17.9
998
8402
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
17.9
147
685
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
27.1
17.8
24
9
N02AA05
ATC
oxycodone; systemic
1.8
17.8
344
2171
R50.9
ICD-10 Finland
Fever, unspecified
2.0
17.8
240
1351
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
17.8
170
843
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
67.6
17.8
20
*
J94.1
ICD-10 Finland
Fibrothorax
+∞
17.7
17
*
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
6.2
17.7
30
49
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.8
17.7
89
328
J67.9
ICD-10 Finland
Hypersensitivity pneumonitis due to unspecified organic dust
96.4
17.6
19
*
J12.8
ICD-10 Finland
Other viral pneumonia
6.6
17.5
28
43
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
3.9
17.3
52
139
M04AA01
ATC
allopurinol; systemic
1.9
17.2
263
1542
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.9
17.1
82
294
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
31.9
17.1
22
7
A01AB09
ATC
miconazole; local oral
2.3
17.0
136
626
R03DA04
ATC
theophylline; systemic, rectal
2.5
17.0
109
454
R03BA02
ATC
budesonide; inhalant
1.9
17.0
236
1340
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
16.9
211
1155
JN4BD
NOMESCO Finland
Extensive body CT
2.1
16.9
183
952
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.3
16.9
64
200
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
6.3
16.8
28
45
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
16.8
260
1530
XF600
NOMESCO Finland
Bloodpressure measurement
2.4
16.7
117
508
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
16.6
414
2800
5AB14, ,
NOMESCO Finland
172.1
16.5
17
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
16.4
502
3578
J43.8
ICD-10 Finland
Other emphysema
12.3
16.4
29
24
C09AA05
ATC
ramipril; oral
1.7
16.2
430
2951
R03AC13
ATC
formoterol; inhalant
2.7
16.0
89
345
A02BC03
ATC
lansoprazole; oral
1.7
16.0
407
2761
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.0
16.0
34
69
XF402
NOMESCO Finland
ECG with work load test
2.0
15.9
185
987
D07AC01
ATC
betamethasone; topical
1.7
15.8
481
3415
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.7
15.8
90
354
48499
ICD-8 Finland
Acute interstitial pneumonia
+∞
15.7
15
*
R04.0
ICD-10 Finland
Epistaxis
2.2
15.6
147
723
AN1
HP
Coronary angiography
1.9
15.5
224
1285
SPAT1255
SPAT
Intravenous administration of medicine
2.3
15.4
122
559
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
15.0
15.4
25
17
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.3
15.3
57
176
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.2
15.3
135
647
J45.8
ICD-10 Finland
Mixed asthma
3.4
15.2
56
172
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
5.7
15.1
28
50
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
15.1
67
230
WX740
NOMESCO Finland
Nitrogen oxide therapy
45.6
15.1
18
*
E66.8
ICD-10 Finland
Other obesity
3.2
15.0
61
199
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
3.4
14.9
53
159
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.9
14.8
198
1106
RS123, ,
NOMESCO Finland
57.4
14.8
17
*
J99.0*M05.1
ICD-10 Finland
Rheumatoid lung disease
57.4
14.8
17
*
M05BA07
ATC
risedronic acid; oral
3.2
14.7
60
196
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
14.7
417
2900
H02AB04
ATC
methylprednisolone; systemic
1.9
14.6
199
1118
M05.1
ICD-10 Finland
Rheumatoid lung disease
81.0
14.6
16
*
M34.0
ICD-10 Finland
Progressive systemic sclerosis
81.0
14.6
16
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
14.5
156
807
R03AC03
ATC
terbutaline; inhalant
2.0
14.4
171
916
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.2
14.4
56
178
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
4.4
14.4
36
84
WZA10
NOMESCO Finland
Extensive medical or dental certificate
5.6
14.3
27
49
M01CB01
ATC
sodium aurothiomalate; parenteral
4.9
14.3
31
64
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
14.3
139
692
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
14.2
86
348
GDA10
NOMESCO Finland
Biopsy of lung
22.5
14.2
20
9
R05
ICPC
Cough
1.7
14.2
316
2059
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
14.2
130
633
R06.2
ICD-10 Finland
Wheezing
2.8
14.1
72
267
D07AB02
ATC
hydrocortisone butyrate; topical
1.7
14.1
372
2534
J43.2
ICD-10 Finland
Centrilobular emphysema
14.6
14.1
23
16
XG405
NOMESCO Finland
Education on PEF monitoring
4.9
14.1
31
65
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
3.7
14.0
45
126
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.7
14.0
77
297
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
14.0
140
705
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.1
13.9
24
40
R06AE07
ATC
cetirizine; oral
1.6
13.8
472
3421
3AC01, ,
NOMESCO Finland
5.8
13.7
25
44
G04BE03
ATC
sildenafil; oral
3.8
13.7
42
114
WZC30
NOMESCO Finland
Teaching
1.8
13.6
240
1461
M34.8
ICD-10 Finland
Other forms of systemic sclerosis
76.0
13.6
15
*
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
5.5
13.6
26
48
3A006, ,
NOMESCO Finland
+∞
13.6
13
*
WX402
NOMESCO Finland
General anaesthesia
1.7
13.3
275
1751
R4190
NOMESCO Finland
Nutritional therapy
2.9
13.2
62
220
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
13.2
212
1255
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
13.1
99
444
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
12.3
13.1
23
19
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
13.0
131
661
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
12.9
457
3330
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.6
12.9
42
119
SPAT1097
SPAT
Recording of ECG
1.8
12.8
227
1383
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
12.7
191
1106
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
5.5
12.6
24
44
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
12.6
138
718
TK800
NOMESCO Finland
Hemodialysis
3.4
12.5
45
136
M34.1
ICD-10 Finland
CR(E)ST syndrome
17.5
12.5
19
11
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.5
12.5
79
327
J80
ICD-10 Finland
Adult respiratory distress syndrome
13.3
12.4
21
16
ZXD05
NOMESCO Finland
Urgent procedure
1.6
12.4
391
2768
R03DC03
ATC
montelukast; oral
1.9
12.4
184
1062
C10AA03
ATC
pravastatin; oral
2.0
12.3
133
689
XA421
NOMESCO Finland
Nocturnal polygraphy
14.5
12.3
20
14
J46
ICD-10 Finland
Status asthmaticus
3.3
12.3
45
138
WPA13
NOMESCO Finland
Palliative consultation
9.8
12.3
24
25
WX400
NOMESCO Finland
Inhalation anesthesy
2.9
12.1
56
197
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.6
12.0
40
115
UJF32
NOMESCO Finland
Coloscopy
1.6
12.0
374
2638
N03AX12
ATC
[U] gabapentin; oral
1.8
11.9
221
1361
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
4.6
11.9
28
62
R2110
NOMESCO Finland
Giving the first information
2.4
11.9
79
335
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.5
11.9
41
121
J15.8
ICD-10 Finland
Other bacterial pneumonia
5.6
11.7
22
40
2AX04, ,
NOMESCO Finland
65.6
11.6
13
*
R03AC18
ATC
indacaterol; inhalant
5.1
11.5
24
48
J42
ICD-10 Finland
Unspecified chronic bronchitis
4.4
11.5
28
64
J84
ICD-10 Finland
Other interstitial pulmonary diseases
+∞
11.5
11
*
I50
ICD-10 Finland
Heart failure
2.5
11.5
70
285
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
3.9
11.4
33
86
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.6
11.4
340
2369
E0000UV, ,
ATC
1.5
11.3
489
3697
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.4
11.3
75
318
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
35.4
11.3
14
*
R03AC12
ATC
salmeterol; inhalant
2.4
11.2
79
344
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
3.9
11.1
32
83
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
3.8
11.1
33
88
ZXE00
NOMESCO Finland
One hour or less
1.5
11.1
480
3628
XQ848
NOMESCO Finland
Dermatological photography
2.8
11.0
55
202
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.5
11.0
38
112
N05CF01
ATC
zopiclone; oral
1.5
11.0
434
3214
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.8
11.0
161
924
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
10.8
241
1559
C08CA02
ATC
felodipine; oral
1.8
10.8
164
951
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
10.7
52
188
F1246, ,
NOMESCO Finland
21.7
10.7
15
7
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
10.7
106
532
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.5
10.6
67
277
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.0
10.6
123
653
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
11.3
10.6
19
17
C08CA05
ATC
nifedipine; systemic
2.1
10.6
105
527
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.0
10.5
126
676
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
3.8
10.5
31
82
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.8
10.4
52
191
J99.1*M35.0
ICD-10 Finland
Respiratory disorders in sicca syndrome [Sjögren]
110.9
10.4
11
*
ZX197, ,
NOMESCO Finland
+∞
10.4
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
10.4
203
1266
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.5
10.4
65
268
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.4
10.3
68
287
L04AB01
ATC
etanercept; parenteral
5.2
10.3
21
41
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
5.2
10.3
21
41
WX723
NOMESCO Finland
CPAP therapy
2.6
10.3
59
233
RS220, ,
NOMESCO Finland
4.5
10.3
25
57
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
10.3
534
4171
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.2
10.2
27
66
RK250, ,
NOMESCO Finland
8.0
10.1
22
28
R01AD08
ATC
fluticasone; nasal
1.6
10.1
294
2028
ZX120, ,
SPAT
4.0
10.1
28
71
XF404
NOMESCO Finland
Ambulatory ECG
1.9
10.0
137
768
A02BA02
ATC
ranitidine; systemic
1.6
10.0
274
1863
A06AD11
ATC
lactulose; oral
1.6
10.0
242
1598
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.1
10.0
99
497
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
10.0
306
2137
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.9
9.9
120
646
RS221, ,
NOMESCO Finland
4.2
9.9
26
63
A02BA03
ATC
famotidine; systemic
2.4
9.9
67
287
J98.6
ICD-10 Finland
Disorders of diaphragm
12.3
9.9
17
14
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
9.8
814
6931
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
9.8
228
1488
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.3
9.8
73
326
N06DX01
ATC
memantine; oral
0.3
9.8
33
945
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
9.7
118
636
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
9.7
421
3162
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
9.7
121
2084
N06AA09
ATC
amitriptyline; systemic
1.9
9.7
125
688
XX4AW, ,
NOMESCO Finland
55.4
9.7
11
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.5
9.6
33
97
R94.2
ICD-10 Finland
Abnormal results of pulmonary function studies
7.9
9.6
21
27
R29
ICPC
Respiratory symptom/complaint other
2.1
9.6
91
449
J01DB01
ATC
cefalexin; oral
1.5
9.5
988
8773
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.8
9.5
47
172
B01AB05
ATC
enoxaparin; parenteral
1.5
9.5
425
3209
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.1
9.5
87
423
R01AD09
ATC
mometasone; nasal
1.5
9.5
460
3529
J05AB01
ATC
aciclovir; systemic
1.6
9.5
256
1732
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.6
9.5
53
207
B01AB04
ATC
dalteparin; parenteral
2.3
9.5
75
344
E66.00
ICD-10 Finland
Metabolic syndrome
2.2
9.5
78
364
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
9.4
430
3259
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
2.5
9.4
61
256
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.3
9.4
20
734
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.4
379
2804
J01DA09
ATC
[U] cefadroxil
1.5
9.3
302
2130
T90
ICPC
Diabetes non-insulin dependent
1.5
9.3
361
2646
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.4
9.3
64
276
SPAT1325
SPAT
Vaccination
1.5
9.3
463
3569
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.8
9.3
156
932
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.9
9.3
27
71
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.7
9.3
50
192
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
3.2
9.2
36
115
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
7.3
9.2
21
29
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.5
9.2
31
90
J01FA09
ATC
clarithromycin; systemic
1.5
9.1
326
2347
J98.1
ICD-10 Finland
Pulmonary collapse
5.1
9.1
19
38
F2680, ,
NOMESCO Finland
15.7
9.0
14
9
Z57.2
ICD-10 Finland
Occupational exposure to dust
9.1
9.0
18
20
J01FA15
ATC
telithromycin; oral
1.9
9.0
109
587
ZXA10
NOMESCO Finland
Bilateral
1.6
9.0
258
1769
1CX01, ,
NOMESCO Finland
18.7
8.9
13
7
RK310, ,
NOMESCO Finland
18.7
8.9
13
7
E000001, ,
ATC
1.6
8.9
221
1464
WX002
NOMESCO Finland
Sedation and analgesia
1.6
8.9
266
1841
R03BB06
ATC
glycopyrronium bromide; inhalant
8.0
8.9
19
24
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.2
8.8
73
341
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.9
8.8
39
135
I25.2
ICD-10 Finland
Old myocardial infarction
1.8
8.7
133
771
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
8.7
88
445
J02AC03
ATC
voriconazole; systemic
11.7
8.6
15
13
UJF92
NOMESCO Finland
Capsular endoscopy
3.1
8.6
34
110
M10.9
ICD-10 Finland
Gout, unspecified
1.8
8.5
130
754
A46
ICD-10 Finland
Erysipelas
1.6
8.5
225
1514
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
8.5
71
334
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
3.9
8.4
24
62
WX727
NOMESCO Finland
Estimation of exercise oxygen therapy
90.6
8.4
9
*
AK3
HP
BLTX (both lung transplants)
+∞
8.3
8
*
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
8.3
8
*
GD1FQ
NOMESCO Finland
Lung ventilation SPECT with low dose CT
+∞
8.3
8
*
J99.1*M34.8
ICD-10 Finland
Respiratory disorders in systemic: sclerosis
+∞
8.3
8
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
8.3
204
1346
M81.4
ICD-10 Finland
Drug-induced osteoporosis
10.8
8.3
15
14
B01AF02
ATC
apixaban; oral
1.6
8.3
231
1572
R21
NOMESCO Finland
Counselling and guidance in rehabilitation
4.1
8.3
22
54
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
7.1
8.3
19
27
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.1
8.3
76
371
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
3.2
8.2
31
97
N02BE01
ATC
paracetamol; systemic, rectal
1.6
8.2
1114
10256
11
HP
Coronary artery bypass surgery
2.5
8.2
52
216
A41.9
ICD-10 Finland
Sepsis, unspecified
2.3
8.2
64
292
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
8.2
226
1534
J93.8
ICD-10 Finland
Other pneumothorax
7.6
8.2
18
24
L01AA01
ATC
cyclophosphamide; systemic
7.6
8.2
18
24
S97
ICPC
Chronic ulcer skin
1.8
8.2
114
644
C01AA05
ATC
digoxin; systemic
1.7
8.1
150
919
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.0
8.1
85
435
TFP20
NOMESCO Finland
Cardiodefibrillation
1.8
8.1
123
712
SPAT1260
SPAT
Consultation of another employee
1.6
8.1
222
1504
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
17.3
8.1
12
7
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.5
8.1
49
200
XG467
NOMESCO Finland
Nocturnal CO2 monitoring
22.2
8.0
11
5
XW000
NOMESCO Finland
Bone marrow biopsy
2.2
8.0
70
335
J92.9
ICD-10 Finland
Pleural plaque without asbestos
3.5
8.0
27
79
A07AA09
ATC
vancomycin; oral
3.4
8.0
28
84
R03BB07
ATC
umeclidinium bromide; inhalant
4.3
8.0
20
47
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.7
7.9
141
855
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.5
7.9
50
208
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.7
7.8
42
161
H03AA01
ATC
levothyroxine sodium; systemic
1.5
7.8
251
1760
H05AA02
ATC
teriparatide; parenteral
8.5
7.8
16
19
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
2.8
7.8
37
133
R03BB05
ATC
aclidinium bromide; inhalant
9.5
7.8
15
16
81
HP
Angiography of the heart and coronary arteries
1.8
7.7
119
692
SPAT1254
SPAT
Administration of medicine
1.6
7.7
208
1402
D07AC13
ATC
mometasone; topical
1.5
7.7
328
2435
C10AA01
ATC
simvastatin; oral
1.4
7.7
647
5416
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
15.1
7.7
12
8
I20.00
ICD-10 Finland
Unstable angina
2.3
7.7
58
261
N19
ICD-10 Finland
Unspecified kidney failure
2.1
7.7
71
347
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.3
7.7
59
268
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.0
7.7
32
107
R01AD58
ATC
fluticasone, combinations; nasal
1.6
7.6
201
1348
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
7.6
179
1168
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.0
7.6
81
418
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
25.2
7.6
10
*
A03
ICPC
Fever
1.7
7.6
161
1025
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
3.2
7.6
29
92
R60.0
ICD-10 Finland
Localized oedema
1.6
7.6
182
1195
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
6.2
7.6
19
31
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
7.5
209
1419
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
7.5
136
829
P70
ICPC
Dementia
0.1
7.5
*
242
H02AB09
ATC
hydrocortisone; systemic
2.9
7.5
35
125
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
3.9
7.4
21
54
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
4.4
7.4
18
41
XX1AW
NOMESCO Finland
Written report from X-ray examination without contrast peformed elsewhere
7.7
7.4
16
21
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.4
229
1593
1CX08, ,
NOMESCO Finland
8.4
7.3
15
18
J93.9
ICD-10 Finland
Pneumothorax, unspecified
8.4
7.3
15
18
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.2
7.3
58
267
RK290, ,
NOMESCO Finland
10.9
7.3
13
12
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
7.3
7
*
J17.1*B25.0
ICD-10 Finland
Cytomegaloviral pneumonitis
+∞
7.3
7
*
J99.0
ICD-10 Finland
Rheumatoid lung disease
+∞
7.3
7
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
2.7
7.3
37
138
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
7.3
103
585
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
7.2
44
180
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
3.7
7.2
22
60
N06DA03
ATC
rivastigmine; oral, transdermal
0.2
7.2
10
476
318
Kela drug reimbursment
Teriparatide
7.4
7.2
16
22
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
4.0
7.2
20
51
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.7
7.2
131
801
J01GB01
ATC
tobramycin; inhalant, parenteral
30.2
7.2
9
*
GX1P5
NOMESCO Finland
Nocturnal CO2 monitoring
20.1
7.1
10
5
J02AC01
ATC
fluconazole; systemic
1.4
7.1
344
2611
RS230, ,
NOMESCO Finland
6.6
7.1
17
26
WPA11
NOMESCO Finland
Developing a plan for palliative care
8.0
7.1
15
19
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
7.1
99
559
L04AB04
ATC
adalimumab; parenteral
3.8
7.1
21
56
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
12.1
7.1
12
10
R03DX07
ATC
roflumilast; oral
12.1
7.1
12
10
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.3
7.1
52
232
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
3.0
7.0
30
102
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
1.9
7.0
89
489
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.2
6.9
56
260
SPAT1310
SPAT
Counselling related to known health issue
1.4
6.9
367
2835
UJD02
NOMESCO Finland
Gastroscopy
2.0
6.9
72
370
G04BE08
ATC
tadalafil; oral
8.3
6.8
14
17
TGW99
NOMESCO Finland
Other minor procedure in thoracic surgery
11.0
6.8
12
11
WYA20, ,
SPAT
4.3
6.8
17
40
GD1FN
NOMESCO Finland
Lung ventilation isotope imaging
40.3
6.8
8
*
1240
FHL
Bronchoscopy
3.3
6.7
24
73
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.7
392
3073
J98.2
ICD-10 Finland
Interstitial emphysema
22.6
6.7
9
*
NG1DA
NOMESCO Finland
X-ray of knees
2.8
6.7
32
116
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.6
135
849
N06AX11
ATC
mirtazapine; oral
1.4
6.6
388
3040
ZXA00
NOMESCO Finland
Right side
1.4
6.6
351
2704
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.4
6.6
45
194
WNF00
NOMESCO Finland
Infection source and contact determination
7.8
6.6
14
18
I50.1
ICD-10 Finland
Left ventricular failure
1.9
6.6
88
490
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
12.3
6.6
11
9
R03AK11
ATC
formoterol and fluticasone; inhalant
2.6
6.6
36
140
-1, ,
NOMESCO Finland
1.4
6.6
316
2393
RK120, ,
NOMESCO Finland
8.7
6.6
13
15
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.9
6.6
79
426
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
6.5
203
1412
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
0.2
6.5
9
362
J01DA01
ATC
[U] cefalexin
1.3
6.5
716
6194
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
5.7
6.5
17
30
SPAT1060
SPAT
Administration of oxygen
5.7
6.5
17
30
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.8
6.5
99
576
B01AC04
ATC
clopidogrel; oral
1.4
6.4
275
2037
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
70.2
6.4
7
*
WPB11
NOMESCO Finland
Palliative sedation
70.2
6.4
7
*
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
7.4
6.4
14
19
Z31.5
ICD-10 Finland
Genetic counselling
2.4
6.4
41
172
J67.0
ICD-10 Finland
Farmer lung
14.4
6.4
10
7
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
14.4
6.4
10
7
XPX04
NOMESCO Finland
Angioscopy
14.4
6.4
10
7
J98.4
ICD-10 Finland
Other disorders of lung
14.4
6.4
10
7
WW200, ,
SPAT
0.7
6.4
202
2805
SBA00
NOMESCO Finland
Microbiological examinations
2.7
6.3
33
125
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.3
478
3897
R03AC19
ATC
olodaterol
8.2
6.3
13
16
TNG10
NOMESCO Finland
Puncture of knee
3.6
6.3
20
56
B01AB10
ATC
tinzaparin; parenteral
1.6
6.3
141
908
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
6.3
205
1438
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
6.0
6.3
16
27
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
6.3
106
634
WX213
NOMESCO Finland
Lower leg blockade
3.9
6.3
18
47
6BA02, ,
NOMESCO Finland
18.1
6.3
9
5
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.7
6.3
109
658
J43.1
ICD-10 Finland
Panlobular emphysema
+∞
6.3
6
*
XV5WT, ,
NOMESCO Finland
+∞
6.3
6
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
6.2
194
1348
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.8
6.2
30
109
JD1FN
NOMESCO Finland
Scintigraphy of gastric function
26.8
6.2
8
*
C02KX01
ATC
bosentan; oral
26.8
6.2
8
*
M05BX04
ATC
denosumab; parenteral
1.8
6.2
93
537
3A064, ,
NOMESCO Finland
7.1
6.2
14
20
R03AL11
ATC
formoterol, glycopyrronium bromide and budesonide; inhalant
3.7
6.2
19
52
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
6.3
6.2
15
24
C08CA01
ATC
amlodipine; oral
1.3
6.2
545
4547
1XC02, ,
NOMESCO Finland
5.4
6.2
17
32
SPAT1104
SPAT
Monitoring of emergency patient
1.8
6.2
89
509
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
3.3
6.2
22
67
I20.91
ICD-10 Finland
Angina pectoris, unspecified
2.8
6.1
30
110
M35.1
ICD-10 Finland
Other overlap syndromes
7.7
6.1
13
17
J34.2
ICD-10 Finland
Deviated nasal septum
2.0
6.1
66
343
I26
ICD-10 Finland
Pulmonary embolism
4.1
6.1
16
39
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.5
6.1
172
1171
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
8.6
6.1
12
14
RF220, ,
NOMESCO Finland
3.1
6.1
24
78
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.1
6.1
24
78
I20.09
ICD-10 Finland
Unstable angina
1.8
6.1
97
572
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.0
331
2559
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
6.0
76
416
OAB36
NOMESCO Finland
Guidance and counselling related to exercise
6.7
6.0
14
21
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
6.7
6.0
14
21
L04AA24
ATC
abatacept; parenteral
10.1
6.0
11
11
XQ855, ,
SPAT
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
665
1708
6.96
269.34
12.5
7.9
5.14
5.06
kpa
0.95
642
1645
664
1704
6.96
269.14
12.5
7.9
7.43
7.42
ph
3.18
503
960
664
1709
6.94
268.14
12.5
7.9
9.54
11.83
kpa
36.63
640
1647
657
1701
6.82
262.79
12.3
7.9
2.11
0.86
mmol/l
10.20
574
1383
230
174
15.86
250.38
3.2
2.5
—
—
—
0
0
526
1268
6.31
221.75
1.6
1.3
489.36
492.93
titre
0.02
171
294
322
476
8.68
217.81
1.7
1.3
5.10
10.03
iu/ml
—
6
8
204
163
14.67
214.32
3.3
1.3
—
—
—
0
0
204
163
14.67
214.32
3.3
1.3
—
—
—
0
0
204
163
14.67
214.32
3.3
1.3
—
—
—
0
0
204
163
14.67
214.32
3.3
1.3
—
—
—
0
0
556
1545
5.56
196.55
13.1
8.1
92.75
95.29
%
13.99
531
1497
260
408
7.73
164.61
1.5
1.2
—
—
—
0
0
881
4008
4.77
157.30
15.5
5.9
—
—
—
0
0
364
858
5.51
151.39
4.7
3.0
10.26
11.00
g/l
1.53
349
783
463
1420
4.52
138.00
15.3
8.6
124.02
120.23
g/l
2.92
449
1389
354
893
5.08
134.68
13.5
9.9
25.26
24.20
mmol/l
5.27
345
878
371
978
4.92
133.70
9.7
4.2
5.39
5.14
kpa
4.74
361
934
366
955
4.95
133.56
9.6
4.2
7.42
7.41
ph
2.74
327
800
989
5355
4.61
128.33
16.7
6.2
0.55
0.65
%
8.43
977
5005
989
5356
4.61
128.27
16.8
6.3
8.89
9.22
%
3.02
976
5012
988
5352
4.60
127.95
16.6
6.2
2.42
2.84
%
9.79
976
5001
347
907
4.86
125.70
11.3
6.7
25.34
24.33
mmol/l
4.04
334
866
297
683
5.35
125.36
2.3
1.9
1.09
1.47
g/l
2.01
273
616
992
5438
4.55
125.07
16.6
6.2
22.20
25.78
%
20.70
979
5144
976
5322
4.41
123.12
15.8
6.1
63.20
58.67
%
24.85
969
5073
821
4015
3.87
120.93
7.5
4.6
—
—
—
0
0
395
1219
4.23
114.20
6.1
3.1
254.20
239.35
ng/l
0.24
374
1127
83
38
23.27
113.42
1.1
1.1
—
—
—
0
0
1002
5742
4.32
113.31
15.5
5.9
0.71
0.62
e9/l
20.00
948
4834
1002
5765
4.29
112.07
15.5
5.9
0.04
0.04
e9/l
1.71
949
4857
194
331
6.72
111.88
1.3
1.2
0.30
0.57
u/ml
—
7
26
315
833
4.68
111.40
19.0
10.6
15.82
15.80
%
0.04
299
803
205
378
6.26
109.31
2.5
1.6
10.72
7.10
iu/ml
0.57
43
93
1003
5852
4.19
107.98
15.7
6.0
1.87
1.85
e9/l
0.10
960
5064
145
188
8.56
106.86
3.2
2.5
—
—
—
0
0
1008
5933
4.18
106.32
16.9
6.1
0.20
0.20
e9/l
0.10
966
5098
205
399
5.92
103.10
11.1
6.7
1.41
1.38
mmol/l
0.11
185
347
186
331
6.40
102.60
3.6
2.2
132.15
128.45
g/l
0.73
98
273
411
1413
3.80
100.37
3.3
1.5
—
—
—
0
0
392
1310
3.86
99.75
15.0
7.0
11.53
11.23
mmol/l
0.30
377
1258
453
1673
3.63
99.08
1.4
1.3
56.96
34.89
iu/ml
1.19
173
514
244
578
4.97
98.06
1.6
1.3
225.89
231.92
u/ml
0.04
225
534
221
502
5.10
93.13
6.7
3.1
26.23
24.78
mmol/l
4.32
216
494
164
283
6.49
93.02
10.6
7.7
104.25
105.34
mmol/l
1.74
150
256
164
283
6.49
93.02
10.6
7.7
11.45
11.31
mmol/l
0.18
150
256
307
909
4.12
92.14
3.5
1.4
—
—
—
0
0
256
679
4.45
88.85
3.0
1.8
2.06
2.48
ug/l
0.14
229
600
138
213
7.13
86.97
1.4
1.2
18.02
2.56
u/ml
0.50
12
11
254
686
4.36
85.92
9.7
4.4
—
—
—
0
0
148
252
6.50
84.87
1.4
1.2
16.23
2.19
u/ml
0.53
22
23
247
660
4.39
84.66
9.0
5.2
1.83
1.55
%
5.59
233
624
100
109
9.86
84.07
1.6
1.2
—
—
—
0
0
458
1870
3.25
82.98
3.5
2.1
—
—
—
0
0
101
115
9.44
82.15
1.4
1.3
—
—
—
0
0
146
254
6.35
81.89
1.4
1.2
13.29
3.25
u/ml
0.83
30
34
232
609
4.42
81.21
9.5
5.4
0.89
0.87
%
0.31
219
576
56
22
26.56
80.76
4.0
4.5
—
—
—
0
0
125
188
7.25
80.56
1.5
1.3
—
—
—
0
0
148
266
6.15
80.28
1.4
1.2
10.28
19.55
u/ml
—
5
8
404
1558
3.32
80.13
1.3
1.3
60.03
12.86
u/ml
1.14
89
547
58
26
23.31
79.61
3.3
1.0
—
—
—
0
0
98
112
9.39
79.45
1.3
1.2
—
—
—
0
0
794
4494
2.99
78.79
6.1
3.4
2246.62
1721.54
ng/l
2.00
753
3946
1000
6443
3.44
78.64
19.6
9.5
5.33
4.35
e9/l
27.01
955
5539
84
84
10.63
75.04
3.2
2.5
16.76
15.96
%
0.90
84
84
63
40
16.51
73.91
48.1
25.9
173.00
109.84
ug/l
4.88
49
31
111
162
7.40
73.40
1.5
1.4
169.44
157.54
au/ml
0.39
34
47
977
6385
3.17
71.25
14.8
6.7
11.90
12.58
umol/l
1.15
962
6106
673
3631
2.78
70.61
7.3
3.2
32.97
36.19
u/l
0.48
658
3416
151
314
5.31
69.77
9.9
4.0
—
—
—
0
0
325
1202
3.28
67.81
1.7
1.6
—
—
—
0
0
428
1868
2.93
66.66
10.6
5.9
1.09
1.04
mmol/l
2.90
405
1721
476
2206
2.83
66.15
10.2
3.1
0.81
0.82
mmol/l
0.45
453
2076
505
2418
2.79
65.85
3.0
1.7
1.65
1.56
mg/l
0.14
442
1904
79
89
9.39
64.60
1.2
1.2
2.42
2.88
g/l
1.04
47
67
79
89
9.39
64.60
1.2
1.2
8.88
7.46
g/l
0.64
44
66
79
89
9.39
64.60
1.2
1.2
0.42
0.41
g/l
0.03
47
66
78
90
9.16
62.61
2.1
2.0
911.64
1243.33
e6/l
1.34
73
79
522
2599
2.69
62.31
7.5
4.4
365.77
363.44
ng/l
0.01
477
2269
78
91
9.06
62.07
1.2
1.2
—
—
—
0
0
897
5842
2.75
61.07
15.8
7.1
1.19
1.21
mmol/l
6.98
867
5376
99
156
6.79
60.84
1.3
1.6
0.74
0.93
g/l
0.50
63
123
45
22
21.16
59.44
1.0
1.1
—
—
—
0
0
47
26
18.72
58.80
3.1
1.3
—
—
—
0
0
137
303
4.94
58.70
2.4
1.4
0.23
0.23
g/l
0.15
130
292
72
82
9.24
58.34
1.1
1.2
—
—
—
0
0
190
544
3.92
58.20
10.6
4.6
25.66
24.86
mmol/l
3.08
183
500
73
85
9.04
58.15
2.3
2.4
29.76
33.80
iu/ml
—
9
13
933
6303
2.73
57.12
24.7
19.7
1.40
1.36
inr
1.53
841
5319
85
123
7.33
56.45
1.4
1.2
3.25
5.29
u/ml
0.54
56
56
44
23
19.77
56.44
1.0
1.0
—
—
—
0
0
63
65
10.14
54.88
2.0
2.1
396.22
644.17
e6/l
0.95
55
53
941
6472
2.67
53.95
18.6
7.7
1.20
1.21
mmol/l
4.85
849
5564
62
65
9.97
53.38
2.3
2.3
176.35
232.19
e6/l
0.81
57
57
99
180
5.87
52.67
5.3
3.1
5.24
4.63
e9/l
1.38
99
180
125
281
4.82
52.40
2.0
2.2
11.98
12.49
mg/l
0.23
116
255
120
276
4.69
48.86
13.5
5.0
3.64
2.70
mmol/l
2.81
107
193
68
90
7.92
48.75
2.4
2.2
—
—
—
0
0
436
2192
2.49
48.68
3.7
2.7
2.27
2.24
g/l
0.59
412
2028
92
169
5.78
48.37
1.3
1.2
368.11
286.42
u/ml
0.66
56
85
415
2051
2.51
47.96
3.7
2.7
19.56
21.95
%
2.48
402
1914
62
78
8.30
46.35
1.1
1.1
—
—
—
0
0
448
2333
2.41
45.78
3.8
2.7
10.74
12.13
umol/l
4.37
433
2179
37
21
18.11
45.61
1.1
1.2
27.32
28.00
s
0.23
37
21
58
69
8.75
45.34
1.6
1.2
0.62
2.57
u/ml
0.82
44
41
296
1284
2.69
44.40
2.2
2.2
0.20
0.20
g/l
0.25
278
1199
266
1095
2.80
44.16
7.9
4.2
0.98
0.85
%
0.55
169
383
105
235
4.77
44.13
5.6
3.0
61.55
59.92
%
0.58
105
235
146
420
3.79
44.01
4.4
2.1
21.43
21.41
s
0.01
134
386
389
1930
2.45
43.99
2.2
1.6
2.80
2.72
g/l
0.31
303
1093
255
1031
2.84
43.77
7.6
4.1
0.68
0.71
%
0.12
164
359
260
1063
2.81
43.69
1.7
1.5
—
—
—
0
0
253
1045
2.77
41.53
2.2
2.3
332.67
384.77
nmol/l
2.80
243
962
35
22
16.32
41.01
1.1
1.1
—
—
—
0
0
35
22
16.32
41.01
1.1
1.1
—
—
—
0
0
35
22
16.32
41.01
1.1
1.1
—
—
—
0
0
627
3894
2.19
40.81
7.6
4.3
7.40
7.40
ph
3.93
523
2834
235
944
2.82
40.62
1.7
1.5
—
—
—
0
0
68
110
6.47
40.60
1.3
1.2
61.85
101.05
u/ml
—
6
6
321
1511
2.50
40.25
5.8
3.7
7.38
7.38
ph
0.06
207
901
824
5724
2.21
39.98
10.7
5.2
32.63
34.69
g/l
20.32
787
5344
42
38
11.39
39.92
2.0
2.2
—
—
—
0
0
99
232
4.54
39.26
1.3
1.2
—
—
—
0
0
172
605
3.13
37.60
1.5
1.4
—
—
—
0
0
54
74
7.57
37.51
2.7
2.8
37.02
37.48
%
0.05
43
40
460
2602
2.19
37.10
4.8
3.1
522.63
541.75
mosm/kgh2o
1.55
433
2292
291
1383
2.43
35.24
3.0
2.9
8.29
8.59
umol/l
0.14
269
1241
35
32
11.21
32.98
1.3
1.5
—
—
—
0
0
944
7229
2.14
31.59
14.9
5.6
7.02
6.87
mmol/l
1.48
915
6934
587
3814
1.99
31.22
3.9
2.7
60.64
82.00
u/l
0.51
566
3529
1031
8192
2.28
31.10
13.5
4.4
20.26
14.07
mm/h
21.30
1017
7579
517
3222
2.01
30.91
7.7
3.0
389.26
361.85
umol/l
5.95
470
2771
296
1500
2.26
30.44
5.9
3.6
6.17
5.82
kpa
4.29
276
1460
290
1461
2.27
30.23
5.9
3.6
2.94
1.84
mmol/l
4.17
247
1236
68
147
4.83
29.70
1.0
1.1
1.62
1.57
g/l
0.33
60
134
256
1262
2.28
27.90
19.6
9.0
—
—
—
0
0
371
2115
2.06
27.89
4.0
2.1
30.25
29.83
s
0.64
357
2058
222
1032
2.39
27.70
8.5
4.3
0.04
0.11
%
1.87
124
324
272
1390
2.21
27.10
4.7
3.4
4.99
4.71
e9/l
0.50
249
1169
526
3416
1.91
26.90
12.1
6.5
—
—
—
0
0
32
35
9.35
26.57
1.1
1.1
5.00
14.00
u/ml
—
7
5
222
1051
2.34
26.50
8.5
4.5
0.25
0.12
%
0.28
123
311
1066
8777
2.23
26.43
20.7
8.6
81.50
81.60
u/l
0.02
1056
8312
33
38
8.89
26.36
1.2
1.2
1.04
1.09
ratio
1.31
28
31
33
39
8.66
25.84
1.3
1.3
—
—
—
0
0
74
191
4.05
25.79
1.5
1.1
57.89
46.64
u/ml
0.18
12
14
691
4989
1.83
24.48
7.2
4.5
44.88
89.38
ng/l
1.65
588
3979
470
3019
1.88
24.27
4.9
2.8
3.76
4.53
e6/l
1.51
446
2776
959
7686
1.96
24.23
8.6
5.1
134.88
1416.51
e6/l
2.23
14
137
251
1311
2.14
23.36
18.4
7.8
1.35
1.43
mmol/l
0.62
245
1287
567
3941
1.78
22.05
5.1
2.3
127.86
243.13
u/l
5.01
539
3723
80
248
3.37
21.33
1.5
1.2
—
—
—
0
0
60
157
3.96
20.53
1.2
1.2
187.57
230.55
miu/ml
—
5
51
595
4260
1.74
20.35
6.7
3.7
48.34
107.11
e6/l
1.48
516
3356
236
1267
2.06
20.18
2.5
2.9
65.10
66.06
g/l
0.93
223
1151
553
3900
1.73
19.81
4.4
3.5
—
—
—
0
0
362
2257
1.84
19.80
11.6
4.7
—
—
—
0
0
514
3563
1.74
19.51
3.1
2.4
3.45
2.96
mg/l
2.98
473
3067
43
90
4.91
19.51
1.2
1.1
130.00
183.85
titre
—
9
13
30
18
17.04
19.22
1.1
1.1
—
—
—
0
0
307
1845
1.87
18.74
4.2
2.5
2.09
1.81
%
3.89
282
1651
36
67
5.50
18.61
1.3
1.1
—
—
—
0
0
201
1050
2.08
18.40
2.3
2.7
—
—
—
0
0
628
4661
1.68
18.07
8.2
4.3
86.01
120.29
e6/l
0.44
527
3452
37
73
5.19
17.95
1.3
1.1
—
—
—
0
0
518
3674
1.68
17.59
6.6
3.6
0.41
0.49
e6/l
0.53
440
2796
94
361
2.73
17.26
6.0
3.6
2.83
1.83
index
1.08
66
192
91
344
2.77
17.22
1.6
1.6
—
—
—
0
0
253
1468
1.90
17.06
2.7
1.8
—
—
—
0
0
660
5009
1.65
17.06
3.8
2.4
74.90
78.88
nmol/l
3.46
617
4397
23
33
7.08
15.29
1.9
1.6
35.39
32.30
%
0.31
23
33
148
745
2.11
14.81
2.5
1.8
1.63
1.54
g/l
0.50
131
649
241
1438
1.83
14.70
3.5
2.6
76.07
68.25
e9/l
2.37
177
1081
27
25
11.01
14.52
4.8
7.8
5.55
5.22
kpa
0.29
27
25
76
291
2.71
14.04
1.2
1.2
130.83
84.81
titre
0.40
12
27
66
244
2.80
13.04
5.4
4.2
2.19
1.54
%
0.40
61
218
181
1025
1.89
12.93
5.2
3.9
108.38
98.94
ng/l
0.58
162
875
167
936
1.90
12.29
6.2
3.1
123.56
126.97
g/l
1.06
152
911
21
17
12.54
12.13
6.4
2.5
1.90
2.21
%
0.20
21
17
38
105
3.70
12.10
1.5
1.2
—
—
—
0
0
319
2165
1.63
11.97
5.7
3.4
1.97
1.65
e6/l
0.34
207
1145
555
4284
1.52
11.77
6.1
3.5
2.33
2.35
mmol/l
1.47
504
3842
622
4931
1.50
11.52
28.3
12.4
0.00
0.00
e9/l
0.23
534
3985
47
156
3.09
11.27
7.1
4.8
—
—
—
0
0
627
4999
1.49
11.18
4.4
3.1
195.79
153.12
ug/l
2.80
597
4588
110
553
2.08
11.01
2.9
3.9
65.42
61.84
mg/l
0.10
87
482
109
553
2.06
10.65
2.9
3.9
64.82
95.53
mg/l
0.49
85
484
783
6567
1.49
10.61
6.4
3.3
75.51
56.46
u/l
4.72
752
6066
19
17
11.32
10.56
4.8
10.1
10.84
10.58
%
0.17
19
17
18
15
12.15
10.35
1.1
1.2
—
—
—
0
0
414
3069
1.51
10.30
6.1
3.8
0.00
0.05
estimate
1.25
155
1004
356
2558
1.54
10.23
2.0
1.8
1126.23
1170.40
nmol/l
0.35
291
1935
100
500
2.08
10.16
2.6
3.8
1.69
3.88
ratio
1.32
57
312
36
109
3.37
10.04
1.1
1.2
—
—
—
0
0
78
355
2.27
10.02
2.5
3.0
2.02
1.78
mg/l
1.47
73
314
199
1250
1.70
9.92
4.1
3.0
4.48
4.45
kpa
0.08
184
1215
34
100
3.46
9.91
1.4
1.7
—
—
—
0
0
78
357
2.26
9.89
3.5
3.6
0.79
0.82
nmol/l
0.18
64
290
82
384
2.21
9.84
1.5
1.5
—
—
—
0
0
127
700
1.90
9.80
7.1
3.2
26.39
25.18
mmol/l
2.05
114
674
48
179
2.75
9.39
1.3
1.4
6.95
6.47
mmol/l
0.38
43
173
44
157
2.87
9.34
1.1
1.1
—
—
—
0
0
19
40
4.81
8.60
1.2
1.3
35.58
24.38
%
0.53
12
29
230
3266
0.64
8.48
3.4
3.6
—
—
—
0
0
16
18
8.98
8.05
1.4
1.1
106.30
177.47
ng/l
—
10
12
57
253
2.31
7.81
1.4
1.5
31.73
31.33
g/l
0.08
47
229
160
1010
1.67
7.77
5.8
4.1
1.21
1.22
mmol/l
1.68
155
874
230
1597
1.54
7.49
1.4
1.3
—
—
—
0
0
43
172
2.55
7.39
1.5
1.9
4.09
4.41
mmol/24h
0.27
38
150
30
99
3.08
7.34
2.0
2.2
8.64
7.92
mmol/l
0.44
30
99
649
5468
1.38
7.29
4.6
3.0
—
—
estimate
—
0
0
36
136
2.69
6.94
1.8
1.5
60.63
63.96
%
0.20
24
88
535
4396
1.37
6.90
4.8
4.3
14.95
8.78
mg/mmol
1.45
385
2836
36
137
2.67
6.84
1.3
1.1
—
—
—
0
0
44
188
2.39
6.61
1.5
1.4
—
—
—
0
0
22
64
3.48
6.58
1.9
2.4
2015.91
1446.55
u/ml
0.21
22
64
35
135
2.64
6.50
1.2
1.3
11.67
13.27
u/l
0.28
30
122
10
7
14.38
6.40
1.1
1.0
—
—
—
0
0
17
31
5.54
6.31
1.5
1.8
—
—
—
0
0
525
4345
1.35
6.30
4.1
3.5
7.14
7.43
mmol/l
0.95
449
3616
246
3277
0.69
6.21
2.5
3.6
0.69
0.79
ug/l
0.75
160
2334
49
226
2.21
6.19
1.4
1.4
8977.86
5427.58
e6/l
0.18
36
156
41
178
2.35
5.97
1.1
1.1
—
—
—
0
0
141
921
1.60
5.97
7.3
4.1
—
—
—
0
0
10
9
11.19
5.80
1.9
2.0
—
—
—
0
0
873
7858
1.34
5.63
8.3
4.8
—
0.43
—
0
21
513
4285
1.33
5.60
4.2
3.5
82.52
49.25
mg/l
2.11
384
2852
687
5983
1.32
5.55
6.2
4.1
0.00
0.00
estimate
-0.00
183
1298
698
6094
1.32
5.53
6.4
4.2
0.02
0.25
estimate
0.47
178
1236
82
474
1.78
5.50
3.0
3.2
308.86
260.96
mg/l
0.29
42
194
68
372
1.87
5.44
1.5
1.5
245.67
270.16
ug/g
0.41
40
236
52
260
2.04
5.39
1.7
1.6
—
—
—
0
0
15
30
5.05
5.26
2.5
3.2
2.89
944.46
ug/l
0.49
15
30
51
256
2.03
5.24
1.2
1.3
69.59
46.19
u/l
0.23
44
220
14
26
5.43
5.23
1.3
1.1
—
—
—
0
0
18
54
3.37
5.17
1.2
1.1
1.00
2.87
u/ml
—
7
23
39
177
2.24
5.17
1.1
1.1
—
—
—
0
0
89
537
1.71
5.15
1.2
1.3
—
—
—
0
0
106
671
1.63
5.12
2.5
2.5
—
—
—
0
0
18
55
3.30
5.03
1.7
1.5
1.00
3.45
u/field
1.56
13
38
178
1269
1.47
5.03
2.8
2.5
15.59
6.91
ug/l
4.23
162
1116
691
6070
1.30
5.03
6.3
4.2
0.00
3.84
estimate
1.08
185
1327
40
188
2.16
4.89
1.4
1.4
—
—
—
0
0
345
2768
1.34
4.84
1.9
1.8
54333823.22
18290429.05
pmol/l
0.44
300
2269
9
10
9.05
4.78
1.0
1.1
—
—
—
0
0
13
25
5.24
4.77
1.4
1.2
—
—
—
0
0
15
34
4.45
4.75
1.1
1.1
1.89
1.41
mmol/l
—
8
23
160
1130
1.47
4.75
3.2
2.5
37.14
40.00
u/l
0.25
145
934
115
758
1.57
4.71
1.2
1.2
—
—
—
0
0
7
5
14.06
4.58
1.1
1.0
0.08
0.08
—
7
5
1100
10376
1.40
4.50
54.9
19.9
26.14
28.44
mg/l
2.07
1069
8867
557
4807
1.28
4.47
4.8
3.7
6.15
6.26
ph
1.63
301
2642
85
529
1.65
4.41
2.4
3.6
4.09
4.32
pmol/l
1.21
73
464
294
2334
1.34
4.39
5.4
3.2
0.84
1.04
e6/l
0.75
187
1321
13
28
4.68
4.37
1.2
2.6
19.48
333.99
ug/l
0.48
13
22
21
79
2.69
4.17
2.9
2.6
7.38
7.34
mmol/l
0.02
16
47
7
7
10.05
4.01
3.4
3.1
111.71
101.00
g/l
—
7
7
22
87
2.56
3.98
1.3
1.2
86.77
99.09
pmol/l
0.75
22
87
10
19
5.30
3.83
2.0
1.6
—
—
—
0
0
34
168
2.05
3.72
1.1
1.1
—
—
—
0
0
31
148
2.12
3.71
2.1
2.7
10.40
10.46
%
0.03
31
148
59
351
1.71
3.67
1.7
1.6
10439.79
17001.96
e6/l
1.11
47
240
21
85
2.49
3.64
1.0
1.1
1.40
4.32
u/ml
—
10
45
16
56
2.88
3.63
1.2
1.1
2.60
1.47
u/ml
—
6
25
951
10091
0.78
3.61
5.9
5.5
4.23
4.37
mmol/l
3.77
867
9231
145
1060
1.41
3.60
1.4
1.4
—
—
—
0
0
15
52
2.91
3.47
1.1
1.1
0.59
0.88
u/ml
—
5
17
263
2121
1.30
3.45
1.3
1.2
1.12
1.55
u/ml
0.72
54
528
944
10003
0.79
3.36
5.7
5.4
1.34
1.41
mmol/l
5.88
852
9072
18
411
0.43
3.33
1.6
1.4
—
—
—
0
0
37
197
1.90
3.32
1.5
1.4
352712.72
91082.33
e6/l
0.83
25
114
49
287
1.74
3.25
1.4
1.3
63.91
62.60
mmol/l
0.08
43
230
79
527
1.53
3.14
1.4
1.3
—
—
—
0
0
32
166
1.95
3.11
2.4
2.5
0.87
1.49
g/24h
0.85
22
94
188
1471
1.33
3.07
3.8
4.2
14.42
22.96
ug/l
0.37
168
1229
7
12
5.86
3.02
1.7
1.3
—
—
—
0
0
7
12
5.86
3.02
1.7
1.3
—
—
—
0
0
7
12
5.86
3.02
1.7
1.3
—
—
—
0
0
22
100
2.22
3.00
1.2
1.1
0.88
2.21
u/ml
0.67
11
56
73
484
1.54
3.00
1.2
1.2
75.51
150.50
u/ml
2.02
21
176
5
5
10.03
2.98
1.0
1.6
—
—
—
0
0
981
10313
0.80
2.96
6.3
6.4
2.38
2.50
mmol/l
4.72
887
9389
8
17
4.73
2.92
2.8
1.5
47.50
40.29
umol/l
—
8
17
14
52
2.71
2.89
1.0
1.1
10.52
7.80
iu/ml
—
5
10
19
83
2.31
2.85
1.1
1.1
0.82
1.14
u/ml
—
7
36
17
71
2.41
2.80
1.1
1.1
3.85
1.39
u/ml
—
8
38
8
18
4.47
2.79
16.6
10.2
5.34
5.38
mmol/l
—
8
18
12
39
3.10
2.77
1.9
1.9
0.64
0.60
mmol/l
0.88
12
39
34
189
1.82
2.72
1.5
1.6
—
—
—
0
0
16
66
2.44
2.71
1.3
1.4
55.73
65.64
%
0.36
11
50
40
235
1.72
2.67
2.8
2.1
1.09
0.89
%
0.90
33
175
30
162
1.87
2.63
1.2
1.3
—
—
—
0
0
15
61
2.48
2.62
1.1
1.0
—
—
—
0
0
12
41
2.94
2.62
1.9
1.5
—
—
—
0
0
39
229
1.72
2.62
1.9
1.8
21.33
30.52
iu/l
0.11
21
87
16
344
0.46
2.59
9.1
12.8
—
—
—
0
0
22
107
2.07
2.58
1.8
2.0
1.55
1.56
u/field
0.00
11
54
5
7
7.17
2.55
1.0
1.4
—
—
—
0
0
6
11
5.47
2.54
1.0
1.1
14.98
36.21
iu/ml
—
6
11
11
37
2.99
2.49
10.7
2.8
14.27
13.45
%
0.62
11
37
12
45
2.68
2.45
1.1
1.4
—
0.06
g/l
—
0
5
13
51
2.56
2.44
1.1
1.3
—
—
—
0
0
18
85
2.13
2.29
3.1
3.0
—
—
—
0
0
155
1238
1.29
2.20
6.3
4.8
7.39
7.36
ph
5.48
133
884
496
4470
1.18
2.15
6.2
4.2
0.00
0.04
estimate
3.80
159
1070
631
5799
1.17
2.15
2.5
2.3
92.31
93.41
pmol/l
0.24
357
3166
9
30
3.01
2.15
2.3
1.5
—
—
—
0
0
20
102
1.98
2.11
2.0
1.4
32.06
28.88
%
0.13
11
64
5
10
5.01
2.07
1.6
1.2
—
—
—
0
0
5
10
5.01
2.07
1.6
1.1
—
—
—
0
0
918
9614
0.84
2.02
5.1
4.6
1.42
1.27
mmol/l
10.26
826
8630
447
4017
1.17
1.98
2.0
1.8
18.74
19.96
nmol/l
0.95
405
3393
141
1132
1.28
1.94
2.0
2.3
211.93
159.39
ug/g
0.81
111
892
6
16
3.76
1.93
1.2
1.0
—
—
—
0
0
389
4331
0.85
1.85
2.2
2.0
1.47
1.29
mmol/l
5.05
343
3560
22
122
1.82
1.85
2.1
1.3
0.19
0.20
nmol/l
0.03
16
98
15
73
2.07
1.81
1.1
1.0
—
—
—
0
0
22
124
1.79
1.76
2.0
1.3
—
—
nmol/l
—
0
0
11
231
0.47
1.75
1.3
1.6
—
—
—
0
0
22
125
1.77
1.72
3.0
2.1
—
—
—
0
0
26
157
1.67
1.66
1.2
1.2
—
—
—
0
0
10
41
2.45
1.64
1.0
1.2
—
—
—
0
0
5
14
3.58
1.61
1.2
1.3
60.20
63.86
ug/l
—
5
14
982
10170
0.86
1.58
6.4
5.8
6.09
6.11
mmol/l
0.20
900
9146
51
366
1.41
1.53
1.6
1.6
0.42
0.32
mg/l
0.43
26
173
6
21
2.87
1.50
1.3
1.1
—
—
—
0
0
56
411
1.38
1.48
8.1
3.7
4.05
3.97
mmol/l
0.63
56
405
302
2688
1.16
1.47
6.0
4.4
1.02
1.02
kg/l
0.61
245
1830
25
389
0.64
1.45
1.2
1.2
—
—
—
0
0
76
588
1.31
1.44
2.7
2.2
0.00
1.61
estimate
0.50
19
156
7
151
0.46
1.44
1.0
1.2
1.68
1.53
g/l
—
7
151
9
39
2.32
1.43
1.4
1.4
2.32
1.62
umol/l
—
9
32
70
540
1.31
1.36
3.7
3.3
70.55
2884.22
u/ml
0.89
65
465
30
199
1.52
1.35
1.4
1.3
12.24
8.61
u/l
0.90
25
149
23
356
0.64
1.33
3.8
5.0
—
—
—
0
0
8
34
2.36
1.29
1.9
2.0
—
—
—
0
0
521
5575
0.89
1.27
4.6
6.2
2.04
3.42
ug/l
2.71
458
4990
825
7896
1.12
1.24
4.7
4.1
15.05
15.08
pmol/l
0.10
772
7078
1076
10477
1.16
1.23
43.9
18.0
—
—
—
0
0
17
101
1.69
1.20
1.5
1.2
—
—
—
0
0
17
101
1.69
1.20
1.5
1.2
—
—
—
0
0
11
57
1.94
1.17
1.1
1.7
5.95
20.01
umol/l
—
6
40
24
158
1.53
1.15
2.0
2.5
—
—
—
0
0
12
65
1.85
1.13
2.0
1.8
—
—
—
0
0
13
74
1.76
1.07
1.5
1.6
—
—
—
0
0
241
2677
0.88
1.07
3.1
3.1
2.50
2.46
mmol/l
5.48
199
2399
12
69
1.75
0.96
1.5
1.4
—
—
—
0
0
21
305
0.68
0.95
1.0
1.1
—
—
—
0
0
12
196
0.61
0.92
1.3
1.7
—
—
—
0
0
13
205
0.63
0.87
1.6
1.4
—
—
—
0
0
6
30
2.00
0.87
1.5
1.4
—
0.44
—
0
5
22
153
1.45
0.86
2.8
2.5
—
—
—
0
0
8
44
1.82
0.86
1.8
1.2
148.88
184.65
mmol/24h
—
8
44
24
332
0.72
0.85
1.1
1.1
—
—
—
0
0
56
686
0.81
0.82
1.1
1.3
—
—
—
0
0
92
786
1.18
0.80
4.1
2.8
0.59
0.62
%
0.56
92
780
1105
10852
1.13
0.79
60.5
24.5
138.89
139.62
mmol/l
14.39
1094
10652
7
122
0.57
0.78
1.0
1.3
—
—
—
0
0
30
226
1.34
0.76
1.2
1.4
1.25
0.88
nmol/l
1.12
24
186
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
1105
10865
1.12
0.72
61.1
24.7
4.05
4.01
mmol/l
4.19
1094
10649
18
126
1.43
0.70
1.8
1.3
9514.00
126330.25
e6/l
1.24
12
81
7
41
1.71
0.70
1.3
1.0
991.86
1494.51
miu/ml
—
7
41
308
2892
1.09
0.61
1.5
1.3
—
—
—
0
0
144
1584
0.90
0.58
1.4
1.4
—
—
—
0
0
8
54
1.48
0.57
1.6
1.3
25.38
30.20
umol/l
—
8
48
418
3984
1.07
0.56
4.2
2.7
—
—
—
0
0
8
55
1.46
0.56
3.4
1.7
38.14
39.34
g/l
—
8
55
367
3485
1.07
0.55
6.5
4.2
0.00
0.00
estimate
0.78
165
1156
322
3046
1.08
0.53
3.7
2.6
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
572.83
183.09
iu/ml
—
6
40
8
120
0.66
0.45
1.1
1.3
—
—
—
0
0
7
50
1.40
0.45
1.4
1.3
10.54
22.87
umol/l
—
7
44
7
51
1.37
0.44
4.1
3.0
—
—
—
0
0
14
104
1.35
0.43
1.2
1.2
33.54
33.95
mmol/l
0.04
14
96
38
322
1.19
0.43
1.9
2.4
157.26
112.38
ug/min
0.23
25
196
18
140
1.29
0.42
1.6
1.5
22.53
34.27
ng/l
0.71
18
140
35
296
1.19
0.40
1.2
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
138
1279
1.09
0.40
1.2
1.3
—
—
—
0
0
452
4365
1.05
0.40
2.6
2.3
—
—
—
0
0
67
598
1.13
0.39
1.9
2.0
—
—
—
0
0
1095
10830
1.07
0.39
28.5
13.2
24.53
25.23
u/l
0.88
1085
10476
9
67
1.35
0.38
1.0
1.1
127.67
135.26
nmol/l
—
9
67
6
87
0.69
0.33
1.0
1.1
—
—
—
0
0
14
110
1.28
0.31
1.2
1.1
—
—
—
0
0
114
1062
1.08
0.31
3.2
2.3
11.68
12.76
nmol/l
0.83
99
936
14
111
1.26
0.30
1.3
1.2
—
—
—
0
0
970
9589
1.05
0.28
6.1
5.2
2.04
2.04
mu/l
0.01
909
8684
8
65
1.23
0.27
3.4
1.6
92.00
94.48
umol/l
—
8
65
43
385
1.12
0.27
2.8
3.4
47.97
111.32
u/ml
1.09
43
370
51
462
1.11
0.26
1.5
1.4
—
—
—
0
0
15
123
1.22
0.25
1.1
1.1
—
—
—
0
0
14
115
1.22
0.23
1.4
1.3
—
—
—
0
0
14
115
1.22
0.23
1.5
1.4
—
—
—
0
0
14
115
1.22
0.23
1.4
1.3
—
—
—
0
0
14
115
1.22
0.23
1.4
1.4
—
—
—
0
0
25
219
1.14
0.22
1.0
1.1
—
—
—
0
0
292
2836
1.04
0.21
5.1
3.9
—
0.14
—
0
35
28
314
0.89
0.21
6.0
3.4
7.22
7.58
mmol/l
0.53
28
305
0
13
0.00
0.21
0.0
1.7
—
7.53
—
0
8
0
14
0.00
0.20
0.0
1.1
—
0.02
—
0
14
17
146
1.17
0.19
1.0
1.1
1.50
98.55
iu/ml
—
6
24
6
53
1.13
0.18
1.2
1.4
25.17
24.79
%
—
6
47
991
9986
0.97
0.18
8.7
7.4
42.44
40.47
mmol/mol
5.39
935
9200
7
58
1.21
0.18
4.1
2.8
—
—
—
0
0
7
61
1.15
0.17
1.0
1.8
12.74
16.24
nmol/l
—
7
53
95
904
1.05
0.17
5.0
2.9
6.20
6.05
ph
0.93
71
647
22
247
0.89
0.17
1.2
1.3
6.12
45.82
e6/l
0.92
17
187
1106
11001
1.04
0.16
61.8
26.7
95.15
85.63
umol/l
6.44
1094
10861
43
399
1.08
0.16
1.0
1.1
—
85.09
titre
—
0
11
27
297
0.91
0.15
1.9
1.8
42.48
43.22
nmol/l
0.08
27
277
9
80
1.13
0.15
1.7
1.5
—
—
—
0
0
9
83
1.08
0.14
1.0
1.1
1.89
2.09
mmol/l
—
9
76
7
88
0.79
0.14
3.3
2.7
—
—
—
0
0
33
304
1.09
0.14
2.7
3.4
65.39
1318.21
u/ml
0.86
28
282
112
1158
0.96
0.12
2.8
2.2
0.00
0.01
estimate
0.50
26
212
10
86
1.16
0.11
1.3
1.3
—
—
—
0
0
5
46
1.09
0.09
1.2
2.3
—
—
—
0
0
68
658
1.04
0.07
2.5
2.8
—
—
—
0
0
1105
11076
0.98
0.06
69.1
30.0
8.43
6.94
e9/l
37.90
1088
10785
24
227
1.06
0.06
1.2
1.3
—
—
—
0
0
1105
11075
0.98
0.05
69.6
30.2
130.27
132.93
g/l
6.05
1098
10928
1105
11074
0.99
0.05
69.0
30.0
4.34
4.40
e12/l
2.95
1088
10782
1105
11074
0.99
0.05
72.2
30.6
39.71
39.70
%
0.01
1097
10920
1105
11074
0.99
0.05
68.7
29.9
30.40
30.49
pg
0.74
1097
10926
1105
11073
0.99
0.05
68.8
29.9
92.70
91.82
fl
6.55
1097
10927
1105
11072
0.99
0.05
69.1
30.0
241.84
237.83
e9/l
1.12
1090
10825
10
93
1.08
0.02
1.8
1.4
—
—
—
0
0
10
107
0.93
0.02
1.1
1.3
—
—
—
0
0
36
368
0.98
0.01
5.4
3.3
1.56
1.58
mmol/l
0.05
36
358
815
8156
1.00
0.00
62.4
26.4
327.83
331.54
g/l
21.35
809
8108
10
102
0.98
0.00
1.0
1.2
290.70
347.45
nmol/l
—
10
81
11
111
0.99
0.00
1.5
1.4
—
—
—
0
0
26
263
0.99
0.00
9.4
3.8
30.29
30.99
mg/l
0.03
18
184
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
235.21
—
0
8
6
59
1.02
0.00
1.3
1.4
—
—
—
0
0
7
79
0.89
-0.00
1.4
1.8
131.86
113.99
ng/l
—
7
79
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.05
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
181.80
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
22.30
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
4.63
—
0
6

Mortality – FinRegistry

Association

Association between endpoint ILD_INSUFFICIENCY and mortality.

Females

Parameter HR [95% CI] p-value
ILD_INSUFFICIENCY 8.21 [6.16, 10.94] < 0.001
Birth year 0.996 [0.99, 1.0] 0.326

During the follow-up period (1.1.1998 — 31.12.2019), 1133 out of 1651 females with ILD_INSUFFICIENCY died.

Males

Parameter HR [95% CI] p-value
ILD_INSUFFICIENCY 7.529 [5.54, 10.23] < 0.001
Birth year 0.988 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 1687 out of 2465 males with ILD_INSUFFICIENCY died.

Mortality risk

Mortality risk for people of age

years, who have ILD_INSUFFICIENCY.

N-year risk Females Males
1 0.882% 1.479%
5 5.567% 7.869%
10 12.156% 19.449%
15 22.803% 33.892%
20 37.258% 52.12%

Relationships between endpoints

Index endpoint: ILD_INSUFFICIENCY – ILD-related respiratory insufficiency

GWS hits: 9

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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