No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
956 |
4. Check minimum number of eventsNone |
956 |
5. Include endpointsNone |
956 |
6. Filter based on genotype QC (FinnGen only) |
850 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H04
- Name in latin
- Epiphora
Similar endpoints
↥List of similar endpoints to
Epiphora
based on the number of shared cases.
Similar with more cases:
- Disorders of lacrimal system
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5034 | 3324 | 1700 |
| Only index persons | 4691 | 3161 | 1530 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.05 |
| Only index persons | 0.10 | 0.12 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 58.49 | 57.92 | 59.66 |
| Only index persons | 58.69 | 58.09 | 59.95 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 850 | 606 | 244 |
| Unadjusted period prevalence (%) | 0.19 | 0.22 | 0.11 |
| Median age at first event (years) | 62.30 | 61.03 | 65.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 883
- Matched controls
- 8830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H04.2
ICD-10 Finland
Epiphora
4503599627370496.0
307.7
877
6
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
598.6
307.7
357
10
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
1979.5
299.8
274
*
H04.10
ICD-10 Finland
Dry eye syndrome
10.3
184.4
240
308
H02.3
ICD-10 Finland
Blepharochalasis
48.8
163.5
96
22
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
1712.3
151.6
143
*
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
799.8
142.1
136
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
4.3
101.2
511
2132
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.3
92.2
600
2929
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
840.6
79.7
77
*
H02.4
ICD-10 Finland
Ptosis of eyelid
39.0
77.7
48
13
S01GX01
ATC
cromoglicic acid; ophthalmic
3.8
72.4
301
1052
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
572.2
55.2
54
*
H02.1
ICD-10 Finland
Ectropion of eyelid
140.8
50.4
53
*
H01.0
ICD-10 Finland
Blepharitis
5.2
46.0
101
213
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
393.7
38.3
38
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
382.8
37.3
37
*
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
35.7
34
*
ZXA10
NOMESCO Finland
Bilateral
2.8
35.6
234
1019
F29
ICPC
Eye symptom/complaint other
3.3
34.6
147
500
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.8
32.7
110
321
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
160.4
29.8
31
*
F03
ICPC
Eye discharge
3.6
28.9
101
302
WX002
NOMESCO Finland
Sedation and analgesia
2.5
28.9
225
1054
R01AD09
ATC
mometasone; nasal
2.2
28.4
458
2912
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
27.2
26
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
27.2
26
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
10.3
24.8
28
28
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.6
24.5
87
262
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
31.0
22.9
30
10
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
5.8
22.4
42
76
WX110
NOMESCO Finland
Infiltration anesthesia
2.2
21.7
665
5158
L17
ICPC
Foot/toe symptom/complaint
2.0
21.7
333
2024
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
214.9
20.7
21
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
20.0
251
1409
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
19.9
194
987
R01AD58
ATC
fluticasone, combinations; nasal
2.1
19.5
243
1360
S18
ICPC
Laceration/cut
1.9
19.4
465
3252
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
19.1
423
2880
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
18.9
298
1809
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.0
18.5
88
316
E0000UV, ,
ATC
1.9
18.4
402
2714
A02BC05
ATC
esomeprazole; systemic
1.9
18.0
397
2684
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
17.8
350
2278
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
17.8
287
1750
CCD30
NOMESCO Finland
Reconstruction of lacrimal canaliculus
183.5
17.6
18
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
17.4
301
1876
M03BX02
ATC
tizanidine; oral
1.9
16.8
569
4356
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
16.1
291
1831
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
15.7
15
*
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
15.7
15
*
R01AD08
ATC
fluticasone; nasal
1.9
15.3
270
1683
R06AX27
ATC
desloratadine; oral
1.9
15.2
262
1620
J02AC01
ATC
fluconazole; systemic
1.8
15.2
379
2622
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.4
15.0
110
491
ZXA00
NOMESCO Finland
Right side
1.9
15.0
261
1618
J01DB01
ATC
cefalexin; oral
2.1
14.7
739
6275
R13
ICD-10 Finland
Dysphagia
2.7
14.6
83
328
L03
ICPC
Low back symptom/complaint
1.8
14.5
290
1873
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.7
14.4
490
3683
H00.1
ICD-10 Finland
Chalazion
4.6
14.3
34
76
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.3
14.3
122
582
H57.1
ICD-10 Finland
Ocular pain
3.7
14.2
46
130
L08
ICPC
Shoulder symptom/complaint
1.9
14.1
235
1433
M19.9
ICD-10 Finland
Arthrosis, unspecified
3.1
14.0
61
208
SPAT1153
SPAT
Removal of sutures
1.8
13.9
306
2027
S01GX08
ATC
ketotifen; ophthalmic
3.3
13.9
54
172
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
4.0
13.9
40
104
UDM02
NOMESCO Finland
Sinoscopy
4.5
13.9
34
78
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
13.9
255
1601
J01AA02
ATC
doxycycline; systemic
1.9
13.9
704
5917
R01AD12
ATC
fluticasone furoate; nasal
1.8
13.7
282
1830
N03AX16
ATC
[U] pregabalin
1.9
13.6
229
1399
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
13.3
391
2801
H10.5
ICD-10 Finland
Blepharoconjunctivitis
5.2
13.2
27
53
CBB30
NOMESCO Finland
Excision of lesion of eyelid
4.0
13.2
38
99
M79.6
ICD-10 Finland
Pain in limb
1.7
13.1
421
3086
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
13.0
86
366
H10
ICD-10 Finland
Conjunctivitis
2.6
13.0
75
299
S01GX09
ATC
olopatadine; ophthalmic
4.0
12.9
37
96
M48.0
ICD-10 Finland
Spinal stenosis
2.1
12.9
142
748
UJF32
NOMESCO Finland
Coloscopy
1.8
12.8
254
1627
M01AH05
ATC
etoricoxib; oral
1.7
12.7
556
4409
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
12.6
372
2658
CCD40
NOMESCO Finland
Percutaneous dacryocystorhinostomy
+∞
12.5
12
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.4
12.2
84
364
R06AE07
ATC
cetirizine; oral
1.7
12.1
395
2887
R03DC03
ATC
montelukast; oral
1.9
12.1
165
936
J31.0
ICD-10 Finland
Chronic rhinitis
2.4
12.1
89
398
ZXA05
NOMESCO Finland
Left side
1.8
12.1
232
1468
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.0
12.0
154
855
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
12.0
212
1307
F01
ICPC
Eye pain
3.7
12.0
38
106
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.6
11.9
71
287
ZXE00
NOMESCO Finland
One hour or less
1.7
11.8
344
2437
N02BE01
ATC
paracetamol; systemic, rectal
2.3
11.8
807
7231
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
14.9
11.8
19
13
J01CA04
ATC
amoxicillin; systemic
1.9
11.7
715
6144
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
11.7
190
1142
SAA02
NOMESCO Finland
Basic examination of mouth
1.7
11.6
578
4687
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.1
11.5
124
647
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
11.5
11
*
H02.2
ICD-10 Finland
Lagophthalmos
+∞
11.5
11
*
CCC99
NOMESCO Finland
Other operation on lacrimal passages
+∞
11.5
11
*
M54.5
ICD-10 Finland
Low back pain
1.7
11.5
334
2363
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.0
11.4
136
736
SPAT1260
SPAT
Consultation of another employee
1.9
11.4
171
1000
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
11.3
234
1508
R53
ICD-10 Finland
Malaise and fatigue
1.7
11.2
239
1554
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
11.1
75
322
H10.4
ICD-10 Finland
Chronic conjunctivitis
10.2
11.0
21
21
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.2
11.0
45
148
L01
ICPC
Neck symptom/complaint
1.9
11.0
159
919
Z01.2
ICD-10 Finland
Dental examination
1.6
10.9
408
3062
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
10.9
148
837
M25.5
ICD-10 Finland
Pain in joint
1.7
10.9
306
2139
SPAT1301
SPAT
No procedures
1.7
10.9
291
2008
H02AB07
ATC
prednisone; oral
2.0
10.9
135
741
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
10.7
212
1346
H04.0
ICD-10 Finland
Dacryoadenitis
60.7
10.6
12
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
10.6
153
882
R07.0
ICD-10 Finland
Pain in throat
2.5
10.6
65
267
H26.4
ICD-10 Finland
After-cataract
2.1
10.5
110
567
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
10.4
10
*
CBN50
NOMESCO Finland
Excision of tarsus and skin
+∞
10.4
10
*
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
+∞
10.4
10
*
H02AB06
ATC
prednisolone; systemic
1.6
10.4
421
3210
N02AX02
ATC
tramadol; systemic, rectal
1.6
10.3
380
2832
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
10.2
450
3494
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
10.2
102
517
D07AC01
ATC
betamethasone; topical
1.6
10.0
318
2281
WX720
NOMESCO Finland
Own respiration
2.6
10.0
57
226
J01EA01
ATC
trimethoprim; systemic
1.7
9.8
252
1712
S01XA18
ATC
ciclosporin; ophthalmic
26.3
9.8
13
5
E000001, ,
ATC
1.8
9.8
174
1069
N03AX12
ATC
[U] gabapentin; oral
1.8
9.7
155
922
S01AX11
ATC
[U] ofloxacin
3.3
9.7
37
117
R06.0
ICD-10 Finland
Dyspnoea
1.6
9.7
255
1744
R05
ICPC
Cough
1.7
9.6
235
1575
A02BC01
ATC
omeprazole; systemic
1.7
9.6
248
1688
A02BC02
ATC
pantoprazole; systemic
1.6
9.6
612
5148
J01FA10
ATC
azithromycin; systemic
1.6
9.5
487
3891
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.0
9.5
41
140
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
9.4
431
3352
A02BC03
ATC
lansoprazole; oral
1.6
9.4
265
1840
CBF99
NOMESCO Finland
Other operation for ectropion
+∞
9.4
9
*
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
9.4
9
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
9.3
327
2393
J01MA02
ATC
ciprofloxacin; systemic
1.6
9.3
335
2466
R21
ICPC
Throat symptom/complaint
1.7
9.3
175
1093
N05CF01
ATC
zopiclone; oral
1.6
9.3
297
2128
A02BA02
ATC
ranitidine; systemic
1.7
9.2
179
1126
TQW40, ,
SPAT
2.0
9.2
102
537
S29
ICPC
Skin symptom/complaint other
1.7
9.2
188
1201
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
9.2
266
1860
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
9.1
612
5174
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
9.1
133
769
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
8.9
168
1047
R03BA08
ATC
ciclesonide; inhalant
2.1
8.9
86
430
M01AB05
ATC
diclofenac; systemic, rectal
1.6
8.9
566
4712
R03AC02
ATC
salbutamol; inhalant
1.5
8.9
480
3856
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.8
163
1010
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.1
8.8
84
418
R06AX26
ATC
fexofenadine; oral
2.3
8.8
67
304
L13
ICPC
Hip symptom/complaint
1.7
8.8
197
1288
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
8.8
77
371
N02BF01
ATC
gabapentin; oral
1.9
8.7
109
599
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.5
8.7
476
3828
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.1
8.6
87
442
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.5
353
2670
G04BD12
ATC
mirabegron; oral
1.8
8.4
124
719
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.8
8.3
40
145
R20.2
ICD-10 Finland
Paraesthesia of skin
2.2
8.3
68
318
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
8.3
202
1347
R05
ICD-10 Finland
Cough
1.7
8.3
199
1323
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
8.2
386
2994
N39.3
ICD-10 Finland
Stress incontinence
2.0
8.1
84
431
L12
ICPC
Hand/finger symptom/complaint
1.7
8.0
161
1020
A97
ICPC
No disease
1.7
8.0
187
1233
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
8.0
330
2484
H02AB04
ATC
methylprednisolone; systemic
1.8
8.0
129
768
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
8.0
183
1201
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.9
263
1887
G44.2
ICD-10 Finland
Tension-type headache
1.8
7.9
125
739
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.9
211
1439
S21
ICPC
Skin texture symptom/complaint
1.7
7.9
143
881
M54.6
ICD-10 Finland
Pain in thoracic spine
2.1
7.9
71
346
R4110, ,
SPAT
1.8
7.8
139
850
R51.80
ICD-10 Finland
Headache
1.8
7.8
136
828
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.6
7.7
257
1844
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.7
7.6
136
834
H02.8
ICD-10 Finland
Other specified disorders of eyelid
25.2
7.6
10
*
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
7.6
141
874
KMAK, ,
NOMESCO Finland
1.5
7.6
409
3246
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
7.5
99
552
SFA20
NOMESCO Finland
Two-surface restoration
1.5
7.5
486
3993
M79.1
ICD-10 Finland
Myalgia
1.7
7.5
133
813
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
7.5
112
651
F16
ICPC
Eyelid symptom/complaint
2.4
7.5
49
208
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.8
7.5
36
131
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
7.5
103
584
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.1
7.5
67
326
N06AX11
ATC
mirtazapine; oral
1.5
7.4
302
2258
WX704
NOMESCO Finland
Intubation
2.0
7.4
76
389
F13
ICPC
Eye sensation abnormal
2.9
7.4
33
115
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
7.3
315
2381
L15
ICPC
Knee symptom/complaint
1.6
7.3
242
1729
R01AD01
ATC
beclometasone; nasal
1.7
7.3
135
834
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
7.3
170
1117
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.6
7.3
237
1686
CBN40
NOMESCO Finland
Excision of tarsus
+∞
7.3
7
*
3752A
ICD-9 Finland
Disorders of lachrymal system, Epiphora
+∞
7.3
7
*
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
7.3
118
703
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
7.3
42
168
M02AA07
ATC
piroxicam; topical
1.5
7.3
314
2377
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
7.2
258
1874
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.6
7.2
235
1674
A04
ICPC
Weakness/tiredness general
1.7
7.1
139
872
M79.7
ICD-10 Finland
Fibromyalgia
2.7
7.1
38
146
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
7.1
259
1889
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.6
7.1
40
158
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
7.1
98
556
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.1
129
795
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
7.1
90
497
M01AH01
ATC
celecoxib; oral
1.6
7.0
163
1071
G51.0
ICD-10 Finland
Bell palsy
3.4
7.0
25
76
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
7.0
376
2968
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.8
6.9
34
125
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
6.9
192
1318
R03BB04
ATC
tiotropium bromide; inhalant
1.9
6.9
88
487
D07AC13
ATC
mometasone; topical
1.5
6.8
244
1770
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.8
545
4627
N05CF02
ATC
zolpidem; oral
1.6
6.8
155
1013
U05
ICPC
Urination problems other
2.2
6.8
54
250
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
6.8
123
756
ZXD20
NOMESCO Finland
Day surgery
1.8
6.8
111
663
WX725
NOMESCO Finland
Noninvasive ventilation
2.2
6.8
56
264
R09.1
ICD-10 Finland
Pleurisy
3.6
6.7
22
63
R96
ICPC
Asthma
1.8
6.7
96
550
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.7
182
1242
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
6.7
94
536
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
6.7
238
1725
L16
ICPC
Ankle symptom/complaint
1.8
6.7
111
666
SPAT1053
SPAT
Memory test
1.7
6.7
124
768
J01FF01
ATC
clindamycin; systemic
1.5
6.6
227
1630
R03AC03
ATC
terbutaline; inhalant
1.7
6.6
115
698
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.2
6.6
26
84
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
6.6
80
434
SPAT1263
SPAT
Sampling
1.5
6.6
356
2802
G03DC05
ATC
[U] tibolone
2.2
6.6
53
247
C10AA07
ATC
rosuvastatin; oral
1.5
6.6
294
2231
R03BA02
ATC
budesonide; inhalant
1.6
6.5
158
1047
B35.1
ICD-10 Finland
Tinea unguium
2.1
6.5
61
302
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
5.4
6.5
18
34
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
6.5
266
1984
G50.1
ICD-10 Finland
Atypical facial pain
3.3
6.4
23
70
R51
ICD-10 Finland
Headache
2.3
6.4
49
223
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
6.4
100
588
M19
ICD-10 Finland
Other arthrosis
2.9
6.4
29
102
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.8
6.4
94
543
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
6.4
88
498
S16
ICPC
Bruise/contusion
2.8
6.4
32
119
R04.0
ICD-10 Finland
Epistaxis
2.0
6.4
70
367
N03AE01
ATC
clonazepam; systemic
2.2
6.4
53
250
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
6.4
161
1078
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.9
6.4
77
418
A03FA02
ATC
cisapride; oral, rectal
2.0
6.3
69
361
SFA10
NOMESCO Finland
One-surface restoration
1.4
6.3
454
3757
R02
ICPC
Shortness of breath/dyspnoea
1.7
6.3
126
795
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.5
6.3
39
162
CBB00
NOMESCO Finland
Excision of chalazion
18.2
6.3
9
5
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.3
124
781
CC1CB
NOMESCO Finland
Dacryocystography
+∞
6.3
6
*
J46
ICD-10 Finland
Status asthmaticus
2.9
6.3
28
98
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.7
6.2
19
52
J01FA06
ATC
roxithromycin; oral
1.4
6.2
335
2629
N17
ICPC
Vertigo/dizziness
1.7
6.2
125
791
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.2
256
1909
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.2
102
611
D09
ICPC
Nausea
2.3
6.2
44
195
R52.9
ICD-10 Finland
Pain, unspecified
1.8
6.1
92
535
F02
ICPC
Red eye
2.4
6.1
40
170
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
6.1
98
581
L84
ICPC
Back syndrome without radiat pain
2.2
6.1
51
241
R07
ICPC
Sneezing/nasal congestion
2.1
6.1
55
268
A07AA09
ATC
vancomycin; oral
4.2
6.1
16
39
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
552
4284
1.77
14.54
4.5
4.1
0.11
0.02
estimate
0.79
94
892
705
5905
1.96
14.35
5.8
4.4
13.11
13.09
mm/h
0.01
671
5489
546
4244
1.75
14.10
4.5
4.1
0.03
1.99
estimate
0.49
100
944
484
3682
1.70
13.10
2.4
2.2
100.38
96.62
pmol/l
0.95
236
1886
241
1514
1.81
12.95
1.4
1.3
25.19
31.81
iu/ml
0.47
84
476
552
4371
1.70
12.67
3.1
2.8
—
—
—
0
0
533
4196
1.68
12.36
4.4
4.1
0.00
0.00
estimate
0.50
96
915
478
3659
1.67
12.34
4.9
4.8
35.98
35.43
g/l
1.41
442
3442
719
6183
1.88
11.86
5.6
4.6
14.90
14.90
pmol/l
0.01
669
5652
806
7219
2.34
11.82
7.0
5.6
2.00
1.94
mu/l
0.24
759
6640
830
7551
2.65
11.39
21.0
16.1
22.10
23.96
mg/l
0.91
716
6205
570
4617
1.66
11.38
11.5
9.4
3.90
4.09
e9/l
1.33
498
4024
483
3754
1.63
11.36
3.4
3.0
124.05
117.32
ug/l
0.30
449
3466
490
3830
1.63
11.20
6.6
6.3
1.21
1.21
mmol/l
0.07
461
3521
221
1410
1.76
11.04
1.4
1.3
10.53
12.76
u/ml
0.18
81
525
712
6152
1.81
10.93
10.1
8.2
79.18
79.87
u/l
0.07
692
5812
530
4244
1.62
10.81
7.6
7.1
1.22
1.22
mmol/l
0.54
467
3644
337
2515
1.55
8.67
1.9
1.7
21.57
20.84
nmol/l
0.37
287
2079
342
2565
1.54
8.58
3.1
2.5
59.35
60.97
u/l
0.17
315
2367
96
514
1.97
8.25
1.2
1.2
204.99
229.51
u/ml
0.13
86
470
524
4332
1.52
8.16
7.5
6.5
11.12
11.11
umol/l
0.00
497
4135
562
4718
1.53
8.11
4.9
4.9
6.58
6.71
mmol/l
0.76
532
4468
341
2580
1.52
8.10
2.7
2.1
187.48
203.90
u/l
0.19
327
2452
590
5017
1.53
7.92
3.9
3.3
47.22
48.90
u/l
0.21
549
4668
154
968
1.72
7.89
2.1
2.2
113.88
125.33
ug/g
0.23
114
759
206
1397
1.62
7.88
2.2
1.9
—
—
—
0
0
464
3768
1.49
7.69
2.7
2.5
79.54
78.88
nmol/l
0.19
410
3355
221
1546
1.57
7.36
4.9
4.0
241.27
390.60
ng/l
0.66
183
1226
255
1843
1.54
7.35
1.4
1.3
0.83
1.60
u/ml
1.56
60
493
157
1035
1.63
6.65
2.2
1.8
—
—
—
0
0
269
2004
1.49
6.60
3.0
2.7
337.48
337.68
umol/l
0.01
235
1760
460
3800
1.44
6.56
15.3
14.5
1.25
1.25
inr
0.01
396
3140
86
487
1.85
6.25
2.7
2.5
10.59
20.06
au/ml
1.54
12
45
98
582
1.77
6.10
1.7
1.6
—
—
—
0
0
175
1210
1.56
6.03
2.2
2.5
22.72
21.67
%
0.47
166
1125
186
1304
1.54
6.02
2.2
2.5
2.34
2.33
g/l
0.08
175
1202
815
7630
1.88
6.02
6.9
6.0
2.70
2.69
mmol/l
0.11
757
7012
78
437
1.86
5.87
1.4
1.3
82.37
45.26
au/ml
—
7
35
60
309
2.01
5.78
2.2
2.3
10.42
10.66
g/l
0.13
53
276
146
978
1.59
5.76
2.3
1.8
—
—
—
0
0
122
782
1.65
5.75
2.1
2.1
388.27
385.42
nmol/l
0.06
117
728
284
2191
1.44
5.67
2.5
2.2
2.80
2.96
mg/l
0.54
240
1869
196
1409
1.50
5.61
2.3
2.5
12.77
12.51
umol/l
0.19
186
1305
390
3187
1.40
5.60
4.5
4.1
0.05
0.03
estimate
0.13
80
756
60
314
1.98
5.54
1.2
1.2
0.19
1.45
u/ml
—
7
20
856
8185
2.50
5.53
32.5
24.8
91.62
91.31
fl
1.34
850
8099
780
7243
1.66
5.52
7.2
6.6
38.68
39.49
mmol/mol
2.44
728
6740
802
7504
1.75
5.49
5.9
5.2
4.65
4.66
mmol/l
0.03
749
6927
856
8187
2.49
5.49
32.9
25.4
39.74
39.80
%
0.13
850
8095
856
8187
2.49
5.49
32.6
24.9
4.39
4.42
e12/l
1.30
842
8003
366
2970
1.40
5.43
3.1
3.6
2.35
2.36
mmol/l
0.69
324
2670
856
8190
2.48
5.43
32.8
25.1
132.52
133.03
g/l
0.52
850
8102
796
7440
1.71
5.37
6.4
5.3
5.87
5.96
mmol/l
1.38
732
6753
200
1457
1.48
5.34
1.7
1.7
1077.53
1209.05
nmol/l
1.28
143
1079
855
8184
2.41
5.27
32.7
24.9
248.53
253.38
e9/l
1.52
843
8030
192
1392
1.48
5.25
3.9
3.1
0.83
0.82
mmol/l
0.67
182
1316
827
7830
1.89
5.12
24.7
19.5
3.96
3.97
mmol/l
0.20
816
7665
839
7983
2.02
5.09
16.4
12.3
25.68
24.57
u/l
0.99
819
7740
61
331
1.91
5.08
2.3
2.4
3.01
2.99
g/l
0.05
54
300
796
7463
1.68
5.01
5.8
5.1
1.49
1.51
mmol/l
0.57
742
6831
233
1769
1.43
4.98
1.8
1.7
0.86
1.34
mg/l
4.07
182
1397
843
8042
2.07
4.96
27.6
21.5
76.98
75.73
umol/l
0.44
837
7939
825
7819
1.84
4.89
24.5
19.3
139.61
139.67
mmol/l
0.31
815
7669
98
622
1.65
4.80
1.7
1.4
—
—
—
0
0
45
224
2.06
4.79
1.3
1.4
—
—
—
0
0
188
1381
1.46
4.77
3.0
2.9
0.91
1.23
e6/l
0.90
100
709
50
260
1.98
4.73
2.5
2.2
0.00
0.00
g/l
-0.00
45
223
63
357
1.82
4.61
2.3
2.4
7.40
7.46
g/l
0.09
56
326
444
3783
1.35
4.61
3.1
2.7
—
—
estimate
—
0
0
283
2251
1.38
4.56
4.2
3.6
0.02
0.01
estimate
0.25
83
731
41
201
2.09
4.55
1.4
1.3
—
—
—
0
0
235
1814
1.40
4.52
1.8
1.7
469.12
32686300.29
pmol/l
1.96
190
1493
169
1234
1.46
4.41
1.8
1.5
—
—
—
0
0
253
1985
1.38
4.40
4.6
3.9
91.66
90.37
%
0.32
247
1940
62
356
1.80
4.36
2.3
2.4
3.65
3.72
g/l
0.17
56
326
110
736
1.56
4.35
2.7
2.3
49.63
38.03
u/l
0.32
92
623
377
3153
1.34
4.35
4.2
3.8
23.17
65.71
ng/l
1.43
267
2330
64
372
1.78
4.32
1.1
1.0
—
—
—
0
0
62
357
1.79
4.32
2.3
2.4
4.08
4.30
g/l
1.53
56
326
63
365
1.78
4.30
1.7
1.8
1.47
1.53
g/l
0.17
56
326
48
256
1.93
4.25
2.0
1.5
—
—
—
0
0
209
1597
1.40
4.24
1.6
1.5
2.35
2.49
g/l
0.51
128
946
55
308
1.84
4.20
2.4
2.5
0.79
1.65
g/l
0.58
48
264
181
1351
1.43
4.18
1.5
1.5
—
—
—
0
0
325
2670
1.34
4.18
3.7
3.2
33.01
31.76
u/l
0.21
307
2523
686
6300
1.40
4.12
26.5
20.2
13.70
13.70
%
0.00
679
6226
27
116
2.37
4.12
1.1
1.1
0.72
2.47
u/ml
—
9
63
53
296
1.84
4.09
1.5
1.6
0.22
0.36
mg/l
1.54
23
129
130
915
1.49
4.07
3.0
2.7
9.03
7.57
umol/l
0.27
113
800
23
93
2.51
3.99
1.3
1.6
50.55
61.67
%
0.60
11
64
106
719
1.54
3.95
2.9
3.1
66.27
66.99
g/l
0.46
98
656
281
2275
1.34
3.94
3.4
3.2
0.50
0.42
e6/l
0.19
202
1682
344
2872
1.32
3.90
3.0
3.4
6.54
7.09
mmol/l
1.71
286
2422
15
49
3.10
3.82
1.1
1.3
—
—
—
0
0
15
49
3.10
3.82
1.1
1.3
—
—
—
0
0
44
238
1.89
3.76
1.7
1.3
—
—
—
0
0
218
1715
1.36
3.65
2.6
3.0
2.46
2.46
mmol/l
0.22
190
1541
78
503
1.60
3.62
1.8
1.7
—
—
—
0
0
13
35
3.75
3.60
1.2
1.1
—
—
—
0
0
132
955
1.45
3.60
4.6
4.3
254.72
248.14
u/l
0.13
127
902
23
100
2.33
3.45
1.3
1.3
—
—
—
0
0
759
7154
1.43
3.42
4.8
4.4
1.29
1.27
mmol/l
0.24
700
6483
167
1278
1.38
3.31
3.1
3.0
2.91
3.15
e6/l
0.10
80
607
34
177
1.96
3.28
1.5
1.5
—
—
—
0
0
101
710
1.48
3.20
3.1
3.6
97.19
84.64
ng/l
0.59
89
617
111
800
1.44
3.09
1.9
2.2
0.20
0.21
g/l
0.72
100
748
314
2655
1.28
3.08
3.6
3.3
17.16
57.00
e6/l
4.15
233
2047
232
1886
1.31
3.06
4.4
4.3
1.02
1.02
kg/l
0.47
168
1261
48
288
1.70
2.98
4.6
4.2
32.36
72.25
mg/l
1.22
42
251
48
288
1.70
2.98
4.6
4.2
135.07
60.60
mg/l
0.31
42
253
159
1233
1.35
2.89
2.0
1.9
29.56
29.22
s
0.37
152
1198
37
209
1.80
2.83
1.5
1.6
19572.52
13980.69
e6/l
0.13
29
152
126
948
1.38
2.77
5.7
8.0
11.87
12.24
kpa
0.36
120
913
126
949
1.38
2.75
5.6
7.9
1.32
0.97
mmol/l
0.46
105
790
303
2581
1.26
2.73
3.0
3.2
1078.23
1335.68
ng/l
0.72
258
2205
377
3295
1.25
2.72
2.2
1.9
1.38
1.33
mmol/l
0.57
311
2728
55
351
1.60
2.72
2.8
1.9
—
—
—
0
0
40
235
1.74
2.69
1.7
1.5
—
—
—
0
0
43
258
1.70
2.69
1.3
1.3
—
—
—
0
0
11
35
3.17
2.65
1.0
1.3
—
—
—
0
0
11
35
3.17
2.65
1.0
1.3
—
—
—
0
0
17
74
2.32
2.59
1.3
1.4
—
—
—
0
0
40
238
1.71
2.59
1.5
1.5
0.01
0.08
iu/ml
0.67
12
39
42
254
1.69
2.56
3.1
2.7
—
—
—
0
0
323
2790
1.25
2.55
3.8
4.2
9.08
8.03
mg/mmol
0.15
177
1702
43
263
1.67
2.52
4.8
3.9
1.13
4.18
ratio
1.45
25
152
126
963
1.36
2.52
7.0
6.9
—
—
—
0
0
44
271
1.66
2.51
1.6
1.4
243.80
291.13
ug/g
0.82
26
164
46
288
1.63
2.47
2.7
1.7
—
—
—
0
0
80
568
1.45
2.45
2.8
1.9
—
—
—
0
0
284
2434
1.25
2.38
4.5
4.1
0.00
0.00
estimate
0.75
95
865
11
40
2.77
2.28
1.9
1.1
—
—
—
0
0
8
23
3.50
2.27
1.1
1.2
—
—
—
0
0
20
100
2.02
2.22
1.2
1.2
0.15
0.19
nmol/l
1.47
14
78
26
143
1.84
2.21
1.5
1.4
—
—
—
0
0
26
143
1.84
2.21
1.5
1.4
—
—
—
0
0
51
339
1.54
2.17
1.5
1.9
10.88
9.94
iu/ml
0.07
11
78
84
619
1.39
2.12
2.9
2.0
—
—
—
0
0
141
1130
1.29
2.05
6.7
6.7
104.30
104.07
mmol/l
0.28
141
1130
12
50
2.42
2.03
1.1
1.1
—
—
—
0
0
10
38
2.65
2.01
1.6
3.6
436.00
1109.03
u/ml
—
10
38
53
363
1.49
1.98
1.4
1.3
—
—
—
0
0
17
84
2.04
1.96
1.1
1.4
4586.78
223871.20
e6/l
—
9
55
12
51
2.37
1.95
1.1
1.2
—
—
—
0
0
20
106
1.91
1.92
2.4
2.4
11.53
28.53
mg/l
—
6
42
43
285
1.53
1.88
1.7
1.6
29.60
12.66
u/ml
—
9
48
102
795
1.32
1.82
1.9
1.7
1.52
1.49
%
0.15
77
687
41
271
1.54
1.82
1.5
1.5
—
—
—
0
0
56
397
1.44
1.78
2.6
2.3
12.09
12.60
nmol/l
0.16
50
355
764
7360
1.28
1.76
20.4
15.9
78.62
78.62
ml/min/173m2
0.00
724
6831
9
36
2.52
1.74
1.0
1.5
—
—
—
0
0
108
855
1.30
1.73
3.1
3.4
5.90
5.78
kpa
0.58
108
828
13
61
2.15
1.72
3.5
2.3
13.13
13.17
%
0.06
13
61
11
48
2.31
1.71
2.3
2.5
—
—
—
0
0
33
212
1.58
1.67
1.2
1.1
—
—
—
0
0
20
112
1.80
1.65
3.3
1.8
31.80
32.22
pg
0.12
20
112
192
1636
1.22
1.65
6.3
5.8
2.39
2.86
ug/l
0.46
176
1446
103
816
1.30
1.65
3.1
3.4
1.96
1.82
mmol/l
0.14
93
698
15
76
1.99
1.65
1.6
1.2
—
—
—
0
0
34
221
1.56
1.64
2.7
3.1
1.56
1.92
index
0.12
16
116
33
213
1.57
1.64
1.2
1.1
—
—
—
0
0
16
84
1.92
1.60
1.1
1.1
—
—
—
0
0
24
144
1.69
1.59
2.1
1.7
43.29
43.43
nmol/l
0.01
24
134
7
26
2.71
1.58
2.4
1.2
—
—
—
0
0
30
192
1.58
1.56
2.4
1.5
—
—
—
0
0
37
249
1.51
1.55
1.2
1.2
—
37.72
—
0
17
46
324
1.44
1.54
1.6
1.4
26.59
28.24
iu/l
0.12
41
278
214
1858
1.20
1.52
2.8
2.7
5.74
6.73
e6/l
0.49
194
1715
154
1298
1.23
1.48
5.0
4.7
20.01
21.54
%
0.71
79
668
5
16
3.14
1.44
1.0
1.5
—
—
—
0
0
20
118
1.71
1.42
1.2
1.3
—
0.68
nmol/l
—
0
8
9
40
2.26
1.40
2.7
2.2
—
—
—
0
0
72
558
1.32
1.38
1.2
1.2
105.46
148.90
u/ml
0.67
26
214
6
23
2.62
1.37
1.5
1.1
844.55
187.00
iu/ml
—
6
23
27
175
1.56
1.35
2.3
1.5
—
—
—
0
0
11
54
2.05
1.33
1.4
1.7
70.32
110.83
ng/l
1.16
11
54
0
40
0.00
1.33
0.0
1.4
—
—
—
0
0
31
210
1.49
1.29
1.3
1.4
—
—
—
0
0
30
205
1.48
1.21
2.3
1.7
3.17
30.08
iu/l
0.49
14
86
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
26
2.32
1.19
1.5
1.7
152.67
133.73
%
—
6
26
13
72
1.82
1.15
2.4
1.4
—
—
—
0
0
0
35
0.00
1.15
0.0
4.6
—
42.40
—
0
5
17
103
1.66
1.13
1.2
1.3
342.06
294.00
pmol/l
0.24
17
91
133
1137
1.20
1.13
5.4
5.1
1.07
1.04
mmol/l
0.39
126
1040
13
74
1.77
1.07
1.3
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
35
254
1.39
1.06
2.9
2.8
0.35
0.37
iu/ml
0.19
20
141
111
940
1.21
1.05
3.4
3.3
0.72
0.79
ug/l
0.43
76
635
23
154
1.51
1.04
2.0
1.5
—
—
—
0
0
20
130
1.55
1.03
2.1
1.5
—
—
—
0
0
7
34
2.07
1.03
1.0
1.3
—
—
—
0
0
9
47
1.92
1.02
1.1
1.0
—
—
—
0
0
9
48
1.88
1.00
1.1
1.1
—
—
—
0
0
7
35
2.01
1.00
1.3
1.3
424.06
104.71
nmol/l
—
7
26
22
148
1.50
0.98
1.5
1.4
—
—
—
0
0
14
222
0.62
0.96
1.4
1.8
—
—
—
0
0
30
217
1.40
0.94
1.6
2.8
12.95
12.72
mg/l
0.08
30
203
11
62
1.78
0.94
1.3
1.1
—
—
—
0
0
22
150
1.48
0.93
1.1
1.2
37.88
21.06
u/l
0.38
16
128
29
209
1.40
0.93
2.9
2.2
118.13
128.69
g/l
1.15
23
172
6
28
2.15
0.91
1.2
1.2
—
88.17
—
0
6
17
110
1.56
0.91
1.2
1.1
—
—
—
0
0
54
432
1.27
0.88
1.5
1.5
—
—
—
0
0
10
57
1.76
0.84
1.3
1.1
—
—
—
0
0
10
57
1.76
0.84
1.3
1.1
—
—
—
0
0
6
111
0.54
0.83
1.3
1.0
—
—
—
0
0
29
214
1.37
0.83
1.2
1.3
314.39
239.74
miu/ml
—
8
98
28
206
1.37
0.82
2.5
1.5
—
—
—
0
0
16
105
1.53
0.82
2.0
1.3
—
—
—
0
0
16
105
1.53
0.82
2.0
1.3
—
—
—
0
0
8
47
1.71
0.81
1.0
1.1
—
—
—
0
0
24
173
1.40
0.79
2.1
1.4
—
—
—
0
0
16
106
1.52
0.79
2.0
1.3
—
—
—
0
0
6
33
1.82
0.79
2.3
1.3
13.33
8.94
mm/h
—
6
33
27
200
1.36
0.77
1.4
1.3
—
—
—
0
0
10
59
1.70
0.76
1.3
1.1
—
—
—
0
0
10
59
1.70
0.76
1.3
1.1
—
—
—
0
0
24
175
1.38
0.75
1.3
1.2
9.39
19.30
e6/l
0.49
18
134
220
2018
1.12
0.75
2.5
2.3
—
—
—
0
0
16
108
1.49
0.74
2.0
1.3
—
—
—
0
0
99
862
1.17
0.73
3.4
3.2
—
—
—
0
0
5
25
2.01
0.72
1.2
1.7
—
—
—
0
0
5
25
2.01
0.72
1.2
1.7
—
—
—
0
0
24
177
1.37
0.71
1.3
1.3
2.63
197.83
e6/l
2.23
19
138
5
26
1.93
0.70
1.4
1.7
—
—
—
0
0
78
668
1.18
0.70
2.7
2.3
8.20
8.15
ug/l
0.01
65
590
80
688
1.18
0.69
4.2
3.8
1.22
1.23
mmol/l
0.28
70
578
16
110
1.46
0.68
2.0
1.3
—
—
—
0
0
16
110
1.46
0.68
2.0
1.3
—
—
—
0
0
18
127
1.43
0.68
1.2
1.4
157.98
157.13
au/ml
—
5
35
15
103
1.46
0.65
1.3
1.4
25.14
28.84
u/l
—
10
84
23
174
1.33
0.60
2.7
3.7
0.70
0.83
nmol/l
0.89
15
142
8
52
1.54
0.59
1.0
1.2
—
—
—
0
0
11
72
1.53
0.59
4.3
4.8
10.27
52.14
u/ml
—
6
24
16
115
1.40
0.57
1.2
1.1
—
20.50
—
0
6
6
37
1.63
0.55
1.0
1.4
—
—
—
0
0
101
904
1.13
0.54
3.8
4.4
9.12
21.52
ug/l
0.72
82
742
11
74
1.49
0.53
3.6
2.6
10.40
10.95
index
—
5
40
18
134
1.35
0.53
1.1
1.3
287.80
241.58
u/ml
—
10
75
6
39
1.54
0.53
1.5
2.6
113.17
98.10
%
—
6
39
78
687
1.15
0.53
1.8
2.0
3.35
3.36
ratio
0.04
58
548
51
436
1.18
0.50
3.3
3.6
48.34
48.00
%
0.03
51
427
11
76
1.45
0.48
1.0
1.1
114.27
109.41
pmol/l
0.11
11
76
37
314
1.19
0.41
1.6
1.9
—
—
—
0
0
43
370
1.17
0.41
1.9
1.9
0.52
1.40
ug/l
2.01
38
329
5
33
1.52
0.41
1.2
1.6
—
—
—
0
0
5
33
1.52
0.41
1.8
1.2
160.42
151.58
pmol/l
—
5
33
5
33
1.52
0.41
1.2
1.6
—
—
—
0
0
5
33
1.52
0.41
1.2
1.6
—
—
—
0
0
5
33
1.52
0.41
1.2
1.6
—
—
—
0
0
11
79
1.40
0.41
2.0
1.6
—
—
—
0
0
7
105
0.66
0.39
1.3
1.1
1.28
1.49
g/l
—
7
100
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
12
89
1.35
0.38
1.9
1.6
—
—
—
0
0
60
535
1.13
0.37
7.8
9.8
1.30
1.31
%
0.06
60
530
9
69
1.31
0.37
1.4
1.2
—
—
—
0
0
6
42
1.43
0.35
1.2
1.4
—
—
—
0
0
6
42
1.43
0.35
1.2
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
10
73
1.37
0.34
1.0
1.1
—
—
—
0
0
13
101
1.29
0.32
2.2
1.5
—
—
—
0
0
7
52
1.35
0.31
1.0
1.2
64.00
88.43
u/l
—
7
47
7
52
1.35
0.31
1.0
1.2
20.00
33.38
u/l
—
7
47
12
93
1.29
0.30
1.4
2.1
88.83
89.81
%
0.29
12
93
58
526
1.11
0.29
2.4
2.9
134.62
126.93
g/l
2.86
58
509
8
64
1.25
0.27
1.0
1.0
—
—
—
0
0
9
76
1.19
0.24
1.0
1.2
—
—
—
0
0
12
96
1.25
0.24
1.3
1.1
7.70
2.08
eliau/ml
—
5
37
10
78
1.29
0.24
1.8
1.4
—
—
—
0
0
53
485
1.10
0.24
4.9
3.7
1.42
1.95
mmol/l
0.44
42
381
6
85
0.70
0.24
1.2
1.3
57.67
60.09
u/l
—
6
76
5
38
1.32
0.23
1.0
1.1
1560.40
1566.84
miu/ml
—
5
38
111
1050
1.07
0.23
5.9
5.1
32.45
33.13
%
0.24
69
667
5
40
1.25
0.22
3.0
2.6
1.40
0.77
index
—
5
40
7
94
0.74
0.22
1.3
1.8
—
—
—
0
0
5
42
1.19
0.21
1.2
1.5
35.40
31.58
umol/l
—
5
36
27
304
0.88
0.21
1.9
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
0.55
—
0
11
0
11
0.00
0.21
0.0
1.1
—
1.19
—
0
11
0
10
0.00
0.21
0.0
5.9
—
9.89
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
69
644
1.08
0.21
2.3
2.8
68.62
65.25
ml/min/173m2
0.30
29
279
0
13
0.00
0.21
0.0
1.2
—
31.13
—
0
8
6
53
1.13
0.18
1.0
1.6
—
417.14
—
0
7
55
513
1.08
0.18
1.7
1.8
3.56
3.47
mmol/l
0.25
38
371
17
148
1.15
0.17
1.4
1.5
—
—
—
0
0
19
214
0.89
0.16
1.4
1.2
—
—
—
0
0
6
77
0.78
0.15
1.5
1.2
1.38
1.57
nmol/l
—
6
69
22
197
1.12
0.15
1.6
2.1
720.49
5090.09
u/l
—
7
77
9
80
1.13
0.15
1.0
1.1
—
—
—
0
0
14
122
1.15
0.13
1.4
1.5
—
—
—
0
0
9
109
0.82
0.13
1.2
1.6
—
—
—
0
0
14
123
1.14
0.12
1.4
1.5
1.62
1.20
ratio
—
7
74
14
123
1.14
0.12
1.4
1.5
0.95
1.07
ratio
—
6
74
14
123
1.14
0.12
1.4
1.5
1.22
0.97
ratio
—
6
74
30
279
1.08
0.11
4.8
3.6
1.55
1.33
mmol/l
0.60
30
274
10
86
1.16
0.11
1.0
1.1
—
—
—
0
0
20
218
0.92
0.10
1.3
1.6
892.76
938.70
mu/l
0.11
15
184
12
106
1.13
0.10
1.8
1.5
—
—
—
0
0
10
87
1.15
0.09
5.9
3.4
—
—
—
0
0
5
48
1.04
0.09
1.2
1.5
5.00
7.35
u/l
—
5
37
6
54
1.11
0.09
2.2
3.7
75.67
129.87
nmol/l
—
6
54
5
60
0.83
0.08
1.0
1.4
—
—
—
0
0
7
64
1.09
0.08
1.4
1.5
—
—
—
0
0
7
64
1.09
0.08
1.4
1.5
—
—
—
0
0
7
64
1.09
0.08
1.4
1.5
—
—
—
0
0
31
293
1.06
0.08
1.6
1.7
—
—
—
0
0
6
74
0.81
0.07
1.2
1.6
72.32
47.77
ug/l
—
6
74
13
143
0.91
0.07
1.1
1.3
—
—
—
0
0
9
86
1.05
0.07
1.1
1.2
—
—
—
0
0
12
109
1.10
0.06
1.2
1.2
3.71
1.66
u/ml
—
7
32
69
705
0.98
0.04
2.4
2.4
0.28
0.50
e6/l
0.75
69
674
23
239
0.96
0.02
1.9
1.5
99.07
324.94
pmol/l
2.00
23
234
12
127
0.94
0.01
1.5
1.6
44.51
55.93
ug/l
—
7
108
15
143
1.05
0.01
1.9
1.6
—
—
—
0
0
20
207
0.97
0.01
1.0
1.1
1.52
1.60
g/l
0.98
20
207
21
216
0.97
0.00
1.0
1.2
1.12
0.90
g/l
2.39
21
216
11
106
1.04
0.00
1.3
1.1
—
—
—
0
0
11
112
0.98
0.00
1.2
1.1
4.40
7.42
u/ml
—
5
45
12
118
1.02
0.00
1.9
1.7
—
—
—
0
0
10
103
0.97
0.00
1.3
1.4
0.23
0.36
nmol/l
—
5
82
34
343
0.99
0.00
2.4
3.3
135.52
1268.62
u/ml
1.45
29
296
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
5
55
0.91
0.00
1.0
1.5
—
—
—
0
0
8
79
1.01
-0.00
2.1
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
13.80
—
0
5
0
9
0.00
-0.00
0.0
8.3
—
5.21
—
0
9
6
69
0.87
-0.00
1.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
5.97
—
0
6
5
50
1.00
-0.00
1.0
1.5
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.1
277.00
292.65
mg/l
—
6
51
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.7
9.29
11.66
umol/l
—
5
44
5
51
0.98
-0.00
1.0
1.5
—
24.00
—
0
5
5
54
0.93
-0.00
1.8
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_EPIPHORA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EPIPHORA | 0.846 [0.73, 0.98] | 0.023 |
| Birth year | 0.995 [0.99, 1.0] | 0.288 |
During the follow-up period (1.1.1998 — 31.12.2019), 339 out of 2954 females with H7_EPIPHORA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EPIPHORA | 0.996 [0.84, 1.18] | 0.961 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 302 out of 1479 males with H7_EPIPHORA died.
Mortality risk
Mortality risk for people of age
years, who have H7_EPIPHORA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | 0.193% |
| 5 | 0.536% | 1.29% |
| 10 | 1.339% | 3.071% |
| 15 | 2.565% | 5.718% |
| 20 | 4.456% | 9.408% |
Relationships between endpoints
↥Index endpoint: H7_EPIPHORA – Epiphora
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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