This is a non-core endpoint: only basic statistics are computed.
Defect, injury or illness of lumbar spine
Z21_DEFECT_INJURY_ILLNE_LUMBAR_SPINE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
147 |
4. Check minimum number of eventsNone |
147 |
5. Include endpointsNone |
147 |
6. Filter based on genotype QC (FinnGen only) |
129 |
Control definitions (FinnGen only)
- Control exclude
- Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Z[AB]
Similar endpoints
↥List of similar endpoints to
Defect, injury or illness of lumbar spine
based on the number of shared cases.
Similar with more cases:
- Additional codes for the location of defect, injury or illness
- Factors influencing health status and contact with health services
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 129 | 86 | 43 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | 44.19 | 41.50 | 49.57 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 135
- Matched controls
- 1350
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZA8.4
ICD-10 Finland
Fault, injury or disease in the lumbar spine
+∞
192.9
135
*
Z20.9
ICD-10 Finland
Contact with and exposure to unspecified communicable disease
54.1
92.5
57
18
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
15.4
58.5
72
93
Z25.1
ICD-10 Finland
Need for immunization against influenza
21.8
45.2
37
23
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
12.5
36.3
42
47
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
7.5
25.3
46
87
Z29.8
ICD-10 Finland
Other specified prophylactic measures
22.6
22.8
33
19
M54.5
ICD-10 Finland
Low back pain
6.1
22.5
96
388
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
15.0
16.2
27
22
ZXA05
NOMESCO Finland
Left side
4.3
13.7
47
149
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
21.8
13.4
19
10
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.9
11.7
30
75
ZXA00
NOMESCO Finland
Right side
3.7
11.3
49
180
M03BC01
ATC
orphenadrine (citrate); systemic
3.5
11.1
58
240
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.1
10.6
35
106
M54.4
ICD-10 Finland
Lumbago with sciatica
3.5
9.9
44
163
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.1
9.8
32
96
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.7
8.9
23
57
R39.1
ICD-10 Finland
Other difficulties with micturition
15.4
8.9
14
10
N03AX16
ATC
[U] pregabalin
3.3
8.7
41
156
Z71.8
ICD-10 Finland
Other specified counselling
2.9
8.4
70
367
IHA10
NOMESCO Finland
Structured mapping of problematic alcohol use
+∞
8.4
8
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.5
7.9
32
110
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.4
7.9
33
116
Z20.8
ICD-10 Finland
Contact with and exposure to other communicable diseases
3.9
7.9
26
78
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
4.4
7.8
21
54
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
7.5
43
182
N02AX02
ATC
tramadol; systemic, rectal
2.7
7.5
69
375
M79.6
ICD-10 Finland
Pain in limb
2.7
7.5
78
451
R07.0
ICD-10 Finland
Pain in throat
4.3
7.1
20
53
R4110, ,
SPAT
3.4
7.0
29
101
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
42.2
6.8
8
*
Z00.0
ICD-10 Finland
General medical examination
3.0
6.8
37
152
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
13.2
6.7
11
9
M01AB05
ATC
diclofenac; systemic, rectal
2.9
6.5
104
724
M03BX02
ATC
tizanidine; oral
2.9
6.4
103
716
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
6.2
63
352
R5110, ,
SPAT
4.4
6.1
16
40
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
58
163
5.49
20.63
3.8
2.6
6.43
4.10
e6/l
0.76
52
75
21
42
5.74
10.43
2.6
1.3
—
—
—
0
0
18
16
12.78
10.42
1.6
1.3
6.38
7.35
mmol/l
0.85
18
16
15
21
7.89
6.92
1.7
2.0
—
—
—
0
0
6
0
+∞
6.29
1.0
0.0
8.08
—
mmol/l
—
6
0
59
342
2.29
5.13
4.0
3.4
0.00
0.00
estimate
-0.00
26
123
50
271
2.34
5.08
3.1
3.3
1.02
1.02
kg/l
2.27
43
166
61
365
2.22
4.86
3.6
2.7
0.00
0.00
estimate
—
10
105
20
84
2.62
3.42
3.5
2.0
618.07
8898.75
u/l
1.00
15
30
49
303
1.97
3.34
3.5
2.6
0.21
0.50
e6/l
1.07
41
219
41
242
2.00
3.16
2.8
2.2
11.82
10.36
e6/l
0.12
36
218
68
477
1.86
3.11
3.6
3.1
0.00
0.01
estimate
—
9
111
55
361
1.88
3.10
3.6
2.9
17.75
19.15
ng/l
0.13
28
211
64
449
1.81
2.86
2.1
1.8
98.70
98.05
pmol/l
0.05
45
231
83
634
1.80
2.76
4.1
3.5
0.00
0.00
estimate
-0.00
24
125
129
1173
3.24
2.65
22.6
12.4
22.18
20.95
mg/l
0.17
116
939
47
309
1.80
2.55
1.8
1.6
—
—
—
0
0
81
625
1.74
2.50
4.1
3.4
0.00
0.00
estimate
-0.00
27
130
8
23
3.63
2.31
1.4
1.2
—
—
—
0
0
6
13
4.77
2.29
1.8
1.7
7.20
8.60
mmol/l
—
6
13
80
631
1.66
2.14
3.9
3.5
0.00
0.00
estimate
-0.00
27
129
101
851
1.74
2.06
8.6
7.6
73.14
75.61
u/l
0.30
101
803
0
51
0.00
1.93
0.0
1.5
—
50.54
—
0
51
36
238
1.70
1.86
2.0
2.6
627.66
749.63
ng/l
0.11
29
186
8
31
2.68
1.69
1.4
1.6
19.40
24.96
u/l
—
8
26
125
1151
2.16
1.56
19.7
12.5
139.50
139.77
mmol/l
0.95
125
1127
125
1152
2.15
1.54
19.5
12.6
3.92
3.93
mmol/l
0.13
125
1123
7
27
2.68
1.53
1.4
1.4
—
—
—
0
0
27
178
1.65
1.40
3.6
2.9
9.79
319.46
ng/l
0.96
14
115
10
48
2.17
1.31
5.1
6.9
25.26
23.88
mmol/l
—
10
48
8
38
2.17
1.20
3.0
3.3
54.66
44.10
%
—
8
38
13
72
1.89
1.20
1.9
1.6
—
—
—
0
0
0
36
0.00
1.16
0.0
1.4
—
—
—
0
0
129
1227
2.15
1.12
22.8
14.5
71.29
72.24
umol/l
0.26
129
1211
34
250
1.48
1.11
1.5
1.3
29.34
21.72
iu/ml
—
10
76
9
48
1.94
1.03
1.4
1.9
—
—
—
0
0
99
891
1.42
0.98
2.9
2.9
32.21
40.32
u/l
1.48
99
855
33
252
1.41
0.88
1.8
1.7
1.25
0.97
mg/l
0.12
23
193
5
23
2.22
0.77
1.2
1.0
0.00
0.00
g/l
—
5
23
30
231
1.38
0.77
1.4
1.3
74.52
9.55
u/ml
0.48
21
94
6
107
0.54
0.76
5.0
4.7
—
—
—
0
0
14
92
1.58
0.76
7.1
6.9
5.26
5.13
kpa
0.24
14
87
14
92
1.58
0.76
7.2
6.9
13.34
13.00
kpa
0.06
14
87
5
25
2.04
0.73
1.2
1.4
0.00
1.36
g/l
—
5
25
7
41
1.75
0.71
1.3
1.4
—
—
—
0
0
23
172
1.41
0.69
2.2
2.5
0.80
0.82
mmol/l
0.56
23
164
22
165
1.40
0.66
1.6
1.7
369.93
430.27
pmol/l
0.75
15
147
16
113
1.47
0.64
6.0
5.9
105.19
104.51
mmol/l
0.24
16
113
8
49
1.67
0.63
4.5
1.7
47.25
38.88
u/l
—
8
44
18
240
0.71
0.62
1.8
2.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
3.33
—
0
6
99
921
1.28
0.58
3.1
3.6
—
—
—
0
0
75
680
1.23
0.54
12.2
10.1
4.89
3.94
e9/l
1.68
70
601
47
408
1.23
0.50
3.0
2.9
27.15
28.33
u/l
0.20
47
389
10
142
0.68
0.49
3.4
2.4
17.35
24.37
%
—
10
132
7
48
1.48
0.47
10.3
8.4
22.90
25.24
mmol/l
—
7
43
11
152
0.70
0.47
2.0
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
3.89
—
0
16
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
11
80
1.41
0.40
2.5
2.9
6.14
5.64
kpa
0.74
11
80
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
6
42
1.45
0.36
1.0
1.3
32.83
35.05
nmol/l
—
6
42
6
46
1.32
0.33
1.7
2.4
1.07
1.42
%
—
6
46
7
54
1.31
0.31
2.1
1.4
—
—
—
0
0
11
85
1.32
0.29
1.0
1.0
—
—
—
0
0
15
122
1.26
0.28
1.2
1.3
545.03
158.42
u/ml
—
6
44
5
74
0.66
0.26
2.0
1.4
—
—
—
0
0
17
142
1.23
0.26
2.8
2.5
0.55
0.71
ug/l
0.62
11
84
31
277
1.15
0.24
1.9
1.5
—
—
—
0
0
29
260
1.15
0.21
2.1
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
11.40
—
0
10
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
3.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
50
1.21
0.20
1.3
1.7
0.26
0.23
g/l
—
6
50
53
562
0.91
0.18
2.6
2.5
—
—
estimate
—
0
0
7
60
1.18
0.18
2.3
1.5
—
—
—
0
0
7
86
0.80
0.15
3.4
3.0
—
—
—
0
0
10
118
0.84
0.15
2.4
1.8
350.30
400.65
nmol/l
—
10
110
32
300
1.09
0.11
5.6
3.7
4.31
10.30
mg/mmol
0.86
25
181
15
166
0.89
0.10
2.3
2.4
13.27
14.73
umol/l
0.24
15
153
5
43
1.17
0.10
2.4
2.5
—
—
—
0
0
5
43
1.17
0.10
2.0
2.3
—
—
—
0
0
25
268
0.92
0.10
2.0
2.0
—
—
—
0
0
17
186
0.90
0.10
3.7
3.8
18.07
21.93
%
—
7
80
6
53
1.14
0.09
2.7
1.8
—
—
—
0
0
6
57
1.06
0.08
6.8
5.4
23.82
24.76
mmol/l
—
6
57
10
112
0.88
0.07
1.4
1.6
—
—
—
0
0
9
85
1.06
0.07
1.6
1.4
22.83
24.80
iu/l
—
9
74
9
85
1.06
0.07
1.4
3.5
4.32
4.57
pmol/l
—
9
75
17
182
0.92
0.06
4.0
2.5
1.06
1.08
e6/l
0.01
11
94
16
168
0.95
0.02
1.9
1.9
—
—
—
0
0
16
153
1.05
0.01
2.4
2.4
2.52
2.45
g/l
0.23
16
139
11
116
0.94
0.01
1.7
1.6
—
—
—
0
0
36
358
1.01
0.00
1.4
1.3
0.62
1.51
u/ml
1.19
17
97
43
432
0.99
0.00
4.6
4.2
35.67
36.87
g/l
0.80
43
412
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
10.34
—
0
5
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
59.13
—
0
8
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
88.80
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
12.33
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
58.50
—
0
6
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
50
1.00
-0.00
2.4
2.2
24.74
24.67
mmol/l
—
5
50
0
5
0.00
-0.00
0.0
1.0
—
1922.60
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
10.80
—
0
5
6
60
1.00
-0.00
1.2
1.1
1.44
1.58
g/l
—
6
60
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
0.93
0.86
g/l
—
6
61
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.27
—
0
5
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: Z21_DEFECT_INJURY_ILLNE_LUMBAR_SPINE – Defect, injury or illness of lumbar spine
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).