No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
417 |
4. Check minimum number of eventsNone |
417 |
5. Include endpointsNone |
417 |
6. Filter based on genotype QC (FinnGen only) |
380 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Coarctation of the aorta
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of heart and great arteries
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 380 | 156 | 224 |
| Unadjusted period prevalence (%) | 0.08 | 0.06 | 0.10 |
| Median age at first event (years) | 8.63 | 6.39 | 10.19 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 394
- Matched controls
- 3936
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
307.7
347
*
Q23.11
ICD-10 Finland
Bicuspid aortic valve
108.4
251.2
131
18
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
+∞
154.6
138
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
22.6
128.2
102
60
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
10.6
126.9
245
528
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
10.6
122.3
194
331
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
63.4
114.0
64
12
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
13.3
107.8
119
124
201
Kela drug reimbursment
Chronic cardiac insufficiency
19.0
107.6
92
62
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
16.0
106.0
101
83
I35.0
ICD-10 Finland
Aortic (valve) stenosis
21.2
103.4
83
49
B01AA03
ATC
warfarin; systemic
9.8
94.3
136
201
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
90.1
83
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
51.9
85.7
50
11
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
39.7
83.4
52
15
61
HP
Catheterization and pressure measurement of the left side of the heart
45.4
79.8
48
12
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
24.1
78.2
58
28
XF402
NOMESCO Finland
ECG with work load test
9.0
69.0
99
142
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
8.0
61.7
98
157
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
12.6
61.7
65
61
XFE00
NOMESCO Finland
Epicardial ultrasonography
19.8
61.1
49
28
Q25.0
ICD-10 Finland
Patent ductus arteriosus
30.4
60.9
41
15
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
17.5
56.3
48
31
XF600
NOMESCO Finland
Bloodpressure measurement
6.7
51.6
96
180
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.8
48.4
87
157
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
14.4
47.6
45
35
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.0
46.0
132
363
FM2CE, ,
NOMESCO Finland
9.2
46.0
60
75
C01AA05
ATC
digoxin; systemic
10.9
45.7
52
54
XF400
NOMESCO Finland
ECG with 12 standard connections
4.7
43.9
136
396
C03DA01
ATC
spironolactone; oral
6.3
43.7
85
165
C03CA01
ATC
furosemide; systemic
4.6
40.7
128
375
XF404
NOMESCO Finland
Ambulatory ECG
6.0
38.4
77
153
Q21.10
ICD-10 Finland
Persistent ostium secundum
12.6
37.4
38
33
205
Kela drug reimbursment
Chronic hypertension
4.5
37.2
113
320
WX872
NOMESCO Finland
Intensive care
8.9
37.0
49
62
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.7
35.6
237
1142
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
131.5
34.3
36
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
42.4
34.1
42
11
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
4.2
32.7
111
339
31
HP
Congenital heart failure surgery
78.7
32.4
36
5
Q25.40
ICD-10 Finland
Aortic hypoplasia
350.4
32.3
32
*
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
58.0
31.9
37
7
ZXE20
NOMESCO Finland
More than three and less than five hours
4.3
31.5
97
275
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
76.4
31.4
35
5
TPH07
NOMESCO Finland
Cathetrisation of artery
4.6
30.4
85
223
5513
FHL
Coarctation resection, plastic or bypass
+∞
29.5
28
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.2
29.5
55
101
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
+∞
27.4
26
*
Q25.3
ICD-10 Finland
Stenosis of aorta
138.7
24.9
26
*
C07AB07
ATC
bisoprolol; oral
2.9
23.6
184
912
ZXD10
NOMESCO Finland
Scheduled procedure
2.9
23.3
186
932
FDJ42
NOMESCO Finland
Percutaneous transluminal angioplasty of thoracic aorta in coarctation
+∞
23.1
22
*
FDJ00
NOMESCO Finland
End to end reconstruction of aorta for coarctation
+∞
23.1
22
*
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
69.3
23.1
26
*
62
HP
Catheterization and pressure measurement of the right side of the heart
88.7
22.9
25
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
48.0
22.6
27
6
C07AB02
ATC
metoprolol; systemic
3.8
22.6
81
252
I50.9
ICD-10 Finland
Heart failure, unspecified
4.7
21.6
54
128
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
6.5
21.6
37
62
K83
ICPC
Heart valve disease NOS
53.1
21.4
25
5
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
19.6
20.8
31
17
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
50.9
20.4
24
5
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
25.0
20.2
28
12
PD5AD
NOMESCO Finland
CT of aorta
8.6
19.8
26
32
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
19.4
146
697
TFP20
NOMESCO Finland
Cardiodefibrillation
5.1
18.9
42
90
81
HP
Angiography of the heart and coronary arteries
6.8
18.6
30
47
Z2221
NOMESCO Finland
Medical doctor
2.6
18.0
146
718
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
8.0
18.0
25
33
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.4
17.6
71
237
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
94.0
16.7
18
*
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
29.0
16.7
22
8
PD5BD
NOMESCO Finland
Extensive CT of aorta
21.2
16.6
24
12
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
177.0
16.6
17
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
31.5
16.3
21
7
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
35.0
15.9
20
6
WX882
NOMESCO Finland
High dependency care
4.1
15.9
46
122
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
+∞
15.7
15
*
C09AA02
ATC
enalapril; systemic
3.2
15.6
69
243
XF640, ,
NOMESCO Finland
12.5
15.3
27
23
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.1
15.1
27
47
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
22.1
14.8
21
10
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
83.2
14.7
16
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
13.7
155
867
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
+∞
13.6
13
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
29.5
13.1
17
6
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
51.8
12.9
15
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
12.9
12.8
22
18
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
33.2
12.7
16
5
FCC45
NOMESCO Finland
Percutaneous insertion of stent into descending aorta
+∞
12.6
12
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
12.2
112
568
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.2
12.2
33
83
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.4
11.9
24
27
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
66.9
11.7
13
*
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
66.9
11.7
13
*
C01BD01
ATC
amiodarone; systemic
9.7
11.6
23
25
74673
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae aortae
+∞
11.5
11
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
36.1
11.3
14
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
10.5
11.1
21
21
AN1
HP
Coronary angiography
3.7
11.1
37
108
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
4.9
11.1
25
54
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
61.6
10.7
12
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
61.6
10.7
12
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
10.5
10.6
20
20
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
4.7
10.6
25
56
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
112.8
10.5
11
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
10.5
10
*
7463A
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[STENOSIS VALVULAE AORTAE CONGENITA]
+∞
10.5
10
*
FMD40
NOMESCO Finland
Replacement of aortic root using pulmonary autograft and reimplantation of coronary arteries (Ross)
+∞
10.5
10
*
ZXD05
NOMESCO Finland
Urgent procedure
2.1
10.3
126
714
I44.2
ICD-10 Finland
Atrioventricular block, complete
9.5
10.1
20
22
B01AB05
ATC
enoxaparin; parenteral
2.2
10.1
103
542
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
41.1
10.0
12
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
26.8
9.9
13
5
WX892
NOMESCO Finland
Monitored bed care
3.1
9.8
43
150
G04BE03
ATC
sildenafil; oral
11.8
9.6
17
15
AB1
HP
AVR mechanical
102.3
9.5
10
*
AP3
HP
Catheterization of the right and left side of the heart
102.3
9.5
10
*
Q20.1
ICD-10 Finland
Double outlet right ventricle
102.3
9.5
10
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
102.3
9.5
10
*
Q20.48
ICD-10 Finland
Single ventricle
30.8
9.4
12
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
+∞
9.4
9
*
FC1BC
NOMESCO Finland
Extensive angiography of thoracal aortta
+∞
9.4
9
*
Z3231
NOMESCO Finland
Registered nurse
2.0
9.3
140
850
ZXE00
NOMESCO Finland
One hour or less
1.9
9.2
168
1089
WX704
NOMESCO Finland
Intubation
3.1
9.1
40
139
Q21.19
ICD-10 Finland
Atrial septal defect NOS
37.6
9.1
11
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
37.6
9.1
11
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.4
9.0
33
103
Q21.0
ICD-10 Finland
Ventricular septal defect
24.7
9.0
12
5
C08CA01
ATC
amlodipine; oral
2.0
8.9
116
667
WX402
NOMESCO Finland
General anaesthesia
2.0
8.9
118
684
RS224, ,
NOMESCO Finland
9.8
8.9
17
18
C07AA07
ATC
sotalol; systemic
7.5
8.8
20
28
C09AA05
ATC
ramipril; oral
2.3
8.8
76
371
C07AG02
ATC
carvedilol; oral
4.3
8.8
23
56
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
14.4
8.7
14
10
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
16.7
8.6
13
8
ZX120
NOMESCO Finland
Intravenous
2.8
8.5
45
174
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
91.9
8.4
9
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
91.9
8.4
9
*
21
HP
Aortic Valve Replacement (AVR)
91.9
8.4
9
*
R4110
NOMESCO Finland
Physiotherapy
2.0
8.4
126
760
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.4
8.4
60
270
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
8.4
8
*
5609
FHL
Other measure in this category
+∞
8.4
8
*
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
+∞
8.4
8
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
8.4
8
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
9.7
8.3
16
17
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
8.2
91
491
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
7.9
237
2903
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
7.9
76
388
602
Kela drug reimbursment
Children's severe malnutrition
4.3
7.8
20
48
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
45.9
7.7
9
*
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
25.5
7.6
10
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.1
7.5
32
110
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
7.4
125
779
Q25.9
ICD-10 Finland
Congenital malformation of great arteries, unspecified
+∞
7.3
7
*
FMA20
NOMESCO Finland
Plastic repair of aortic valve for stenosis
+∞
7.3
7
*
Q23.20
ICD-10 Finland
Congenital mitral stenosis
+∞
7.3
7
*
74659
ICD-8 Finland
Congenital anomalies of heart, Maleformatio valvulae mitralis
+∞
7.3
7
*
J01CA04
ATC
amoxicillin; systemic
2.4
7.3
350
3021
K78
ICPC
Atrial fibrillation/flutter
3.7
7.2
23
65
I50.0
ICD-10 Finland
Congestive heart failure
4.1
7.2
20
51
207
Kela drug reimbursment
Chronic arrhythmias
2.6
7.1
42
172
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
4.2
6.9
18
44
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
6.9
164
1131
UGC02
NOMESCO Finland
Rigid bronchoscopy
11.2
6.8
12
11
ZXX09
NOMESCO Finland
Extent of procedure, more than 8 units
40.7
6.8
8
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
17.0
6.8
10
6
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
22.9
6.7
9
*
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
12.5
6.6
11
9
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.8
6.5
20
55
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
70.9
6.4
7
*
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
70.9
6.4
7
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
8.4
6.4
13
16
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.7
6.3
34
133
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
18.4
6.3
9
5
Q20.00
ICD-10 Finland
Common arterial trunk
+∞
6.3
6
*
FDH10
NOMESCO Finland
Reconstruction of interrupted or hypoplastic aortic arch using patch
+∞
6.3
6
*
FDJ30
NOMESCO Finland
Reconstruction of aorta for coarctation using tube graft
+∞
6.3
6
*
FDH96
NOMESCO Finland
Other operation for interrupted or hypoplastic aortic arch
+∞
6.3
6
*
G25.1
ICD-10 Finland
Drug-induced tremor
+∞
6.3
6
*
1CX08, ,
NOMESCO Finland
+∞
6.3
6
*
74729
ICD-8 Finland
Other congenital anomalies of circulatory system, Maleformationes aortae aliae
+∞
6.3
6
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.3
6.1
23
73
I15.8
ICD-10 Finland
Other secondary hypertension
12.8
6.1
10
8
XQ903
NOMESCO Finland
Production of other scan or drawing
12.8
6.1
10
8
C07AB03
ATC
atenolol; systemic
3.7
6.1
19
53
I50.1
ICD-10 Finland
Left ventricular failure
4.0
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
257
703
8.63
101.96
8.0
3.9
1239.86
897.68
ng/l
0.80
241
591
122
177
9.53
85.25
4.9
3.5
166.62
172.93
ng/l
0.05
108
162
248
1198
3.88
37.85
45.0
10.1
1.66
1.18
inr
18.84
220
984
78
188
4.92
31.04
2.4
2.2
15.42
9.88
ug/l
1.33
73
175
103
370
3.41
23.14
9.9
12.7
7.14
6.55
mmol/l
0.37
103
357
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
42
80
5.75
21.55
34.2
8.5
0.39
0.33
iu/ml
0.47
25
47
123
542
2.84
18.98
7.3
3.8
1850.93
703.75
ng/l
1.88
106
373
158
798
2.63
18.58
3.5
2.8
—
—
—
0
0
29
45
6.87
18.15
5.2
5.1
77.31
102.20
%
3.37
29
45
114
495
2.83
17.97
2.7
2.9
2.52
2.42
g/l
1.37
108
466
106
451
2.84
17.29
2.8
3.0
22.34
24.04
%
0.68
100
430
118
533
2.73
17.15
2.8
2.9
14.84
14.33
umol/l
0.29
111
505
59
208
3.16
13.24
21.7
6.8
87.39
93.65
%
1.05
59
208
218
1443
2.14
12.26
4.0
3.1
—
—
estimate
—
0
0
52
180
3.17
12.00
34.9
14.4
16.01
16.29
%
0.29
52
173
75
320
2.66
11.83
28.5
11.5
14.31
13.22
kpa
0.83
75
310
75
320
2.66
11.83
28.5
11.5
5.14
5.24
kpa
0.46
75
308
72
313
2.59
10.89
29.4
11.8
0.78
0.47
mmol/l
0.29
66
267
151
910
2.07
10.47
11.0
6.0
78.36
89.90
%
5.71
151
901
18
15
12.50
10.44
5.2
4.9
5.16
4.91
kpa
0.56
18
15
18
15
12.50
10.44
5.2
4.9
6.38
5.97
kpa
1.06
18
15
64
270
2.63
10.26
24.0
12.1
118.50
124.37
g/l
1.41
64
263
87
438
2.26
9.44
14.4
10.0
106.20
104.76
mmol/l
1.95
87
438
46
174
2.86
9.06
4.8
6.7
189.46
170.48
%
0.91
46
174
69
327
2.34
8.58
28.4
13.2
1.19
1.33
mmol/l
0.91
69
320
256
1935
1.92
8.53
13.7
6.8
6.57
6.48
mmol/l
0.12
247
1827
136
850
1.91
8.10
2.6
2.9
2.78
2.70
mg/l
0.19
125
751
13
10
13.38
7.92
3.7
1.7
100.38
93.40
g/l
—
13
10
221
1617
1.83
7.90
10.0
7.9
18.49
15.15
umol/l
0.99
210
1548
150
999
1.81
7.13
4.0
3.2
34.13
34.49
ng/l
0.01
97
618
181
1302
1.72
6.41
8.9
6.9
36.36
37.01
g/l
0.70
176
1250
41
179
2.44
6.08
6.1
9.3
1.30
1.37
%
0.16
41
179
25
85
3.07
5.94
2.0
1.6
—
—
—
0
0
40
175
2.43
5.91
6.2
9.5
0.71
0.60
%
1.37
40
175
127
851
1.72
5.67
3.2
2.3
426.94
314.32
u/l
0.49
122
820
12
16
7.69
5.67
1.8
3.7
—
—
—
0
0
31
125
2.60
5.42
4.3
5.1
24.97
24.70
mmol/l
0.22
31
119
29
113
2.69
5.42
1.6
1.9
1.31
1.31
g/l
0.00
19
102
212
1654
1.61
5.07
3.7
3.6
94.10
100.36
ug/l
0.27
203
1580
321
2791
1.80
4.94
16.4
12.4
90.73
90.83
ml/min/173m2
0.03
299
2466
83
513
1.78
4.84
6.9
9.1
1.27
1.35
mmol/l
0.09
71
430
33
146
2.37
4.77
17.9
10.6
23.68
24.76
mmol/l
0.75
33
138
254
2094
1.60
4.62
13.2
12.1
4.06
3.83
e9/l
0.84
226
1785
20
70
2.95
4.55
1.9
1.5
—
—
—
0
0
44
229
2.04
4.30
2.8
2.7
71.38
72.29
ml/min/173m2
0.05
21
96
78
492
1.73
4.21
2.0
2.0
—
—
—
0
0
376
3494
2.64
4.21
24.9
16.2
72.89
71.96
umol/l
0.30
376
3461
91
606
1.65
4.00
13.7
9.5
1.21
1.18
mmol/l
0.24
91
575
6
5
12.14
3.77
7.5
11.4
12.28
10.30
%
—
6
5
17
61
2.86
3.73
2.8
4.2
—
—
—
0
0
199
1610
1.47
3.55
13.4
10.3
1.19
1.22
mmol/l
4.77
183
1446
76
498
1.65
3.54
24.4
14.3
25.11
24.78
mmol/l
0.57
76
498
25
113
2.29
3.49
10.5
9.2
1.50
1.64
%
0.48
25
103
66
421
1.68
3.40
11.6
8.8
1.90
1.01
mmol/l
3.10
58
321
55
339
1.72
3.21
12.2
9.7
9.58
9.48
kpa
0.16
55
332
270
2346
1.48
3.17
8.5
8.1
91.93
91.28
u/l
0.05
260
2246
68
446
1.63
3.15
12.1
8.6
5.05
5.07
kpa
0.10
68
436
23
106
2.24
3.08
6.6
2.3
628.40
312.42
ug/l
0.66
23
100
61
394
1.65
3.00
1.8
1.9
—
—
—
0
0
58
386
1.59
2.54
1.9
1.9
—
—
—
0
0
55
362
1.60
2.52
11.6
8.5
25.11
24.30
mmol/l
2.31
55
355
17
77
2.26
2.40
1.2
1.4
—
—
—
0
0
17
77
2.26
2.40
1.2
1.4
—
—
—
0
0
65
451
1.53
2.38
5.9
5.0
10.95
7.34
umol/l
0.82
59
408
17
78
2.23
2.34
2.1
1.9
—
—
—
0
0
8
24
3.38
2.19
3.4
2.6
107.00
106.29
mmol/l
—
8
24
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
8
24
3.38
2.19
1.4
2.1
176.62
130.50
%
—
8
24
356
3355
1.62
2.15
20.8
14.2
30.03
22.15
mg/l
3.89
307
2633
68
487
1.48
2.14
1.7
1.6
477.28
26835309.09
pmol/l
0.50
58
436
94
718
1.40
2.10
6.6
3.1
2.28
1.26
mg/l
1.27
65
550
17
82
2.12
2.09
2.1
2.1
—
—
—
0
0
5
10
5.04
2.07
1.0
1.3
—
—
—
0
0
17
83
2.09
2.03
1.2
2.0
—
—
—
0
0
60
433
1.45
1.83
7.6
9.1
23.85
23.71
mmol/l
0.18
60
433
14
67
2.13
1.77
3.0
3.9
266.33
180.25
e6/l
—
9
44
8
30
2.70
1.73
1.1
1.1
—
—
—
0
0
7
24
2.95
1.73
3.7
2.6
1.19
1.19
mmol/l
—
7
24
5
13
3.88
1.72
2.2
1.2
370.40
1105.85
u/l
—
5
13
20
111
1.84
1.71
1.4
1.5
—
—
—
0
0
22
126
1.79
1.71
1.8
2.0
—
—
—
0
0
13
62
2.13
1.67
4.4
4.5
5.72
9.07
pmol/l
0.96
13
62
13
62
2.13
1.67
1.5
1.8
—
—
—
0
0
6
19
3.19
1.66
2.3
1.2
—
—
—
0
0
8
31
2.61
1.66
4.8
2.8
1.00
0.81
index
—
8
31
11
49
2.28
1.64
18.2
15.9
104.27
104.93
mmol/l
0.22
11
42
18
98
1.87
1.64
1.2
1.1
—
—
—
0
0
115
950
1.30
1.51
4.2
2.9
62.26
60.15
u/l
0.18
106
895
6
21
2.88
1.51
5.0
6.5
—
—
—
0
0
38
261
1.50
1.50
3.3
3.2
—
—
—
0
0
56
737
0.72
1.49
3.1
3.8
21.91
21.62
%
0.04
25
282
12
59
2.06
1.44
6.1
2.4
1.14
1.31
ratio
—
6
31
32
214
1.54
1.43
1.7
1.7
—
—
—
0
0
14
76
1.87
1.31
1.3
1.8
—
—
—
0
0
33
227
1.49
1.31
4.7
4.9
14.61
25.12
ug/l
0.20
24
184
37
261
1.46
1.30
9.9
6.5
—
—
—
0
0
20
122
1.67
1.29
1.8
1.9
—
—
—
0
0
12
62
1.96
1.28
3.8
3.6
4.88
4.93
kpa
0.17
12
62
107
896
1.26
1.25
3.8
3.6
0.00
0.02
estimate
0.88
35
326
316
2983
1.29
1.24
4.8
4.6
4.37
4.59
mmol/l
4.14
305
2855
5
19
2.65
1.22
2.4
4.4
397.40
773.16
mg
—
5
19
5
19
2.65
1.22
1.4
1.3
—
—
—
0
0
5
19
2.65
1.22
1.2
1.1
—
—
—
0
0
27
183
1.51
1.16
2.0
2.5
8793.85
3901.39
u/l
0.31
13
61
8
39
2.07
1.15
1.1
1.2
—
—
—
0
0
8
39
2.07
1.15
1.1
1.2
—
—
—
0
0
8
39
2.07
1.15
1.1
1.2
—
—
—
0
0
0
35
0.00
1.15
0.0
3.3
—
2.53
—
0
28
23
151
1.55
1.14
1.6
1.3
—
—
—
0
0
40
296
1.39
1.11
2.9
2.2
—
—
—
0
0
5
21
2.40
1.09
5.8
10.0
1.98
1.83
mg/l
—
5
16
21
310
0.66
1.06
1.8
1.7
3.59
3.59
mmol/l
0.01
14
209
44
338
1.34
0.99
2.9
2.3
—
—
—
0
0
0
29
0.00
0.98
0.0
2.8
—
—
—
0
0
9
50
1.82
0.97
1.4
2.1
—
—
—
0
0
30
218
1.41
0.94
2.0
3.3
0.45
0.11
e6/l
1.04
30
206
191
1741
1.19
0.93
3.5
3.6
0.00
0.00
estimate
-0.00
38
318
12
71
1.71
0.89
1.6
1.6
—
—
—
0
0
8
43
1.88
0.87
1.1
1.2
—
—
—
0
0
6
113
0.52
0.84
1.2
1.6
85.58
56.97
ug/l
—
6
99
8
46
1.75
0.83
1.1
1.2
—
—
—
0
0
46
568
0.78
0.81
2.3
2.7
1.22
0.69
ug/l
0.54
25
305
310
2966
1.21
0.80
4.7
4.5
1.36
1.40
mmol/l
1.21
301
2819
313
2998
1.21
0.79
5.3
5.0
2.61
2.76
mmol/l
2.67
303
2855
21
148
1.44
0.79
1.2
1.4
—
—
—
0
0
42
521
0.78
0.77
1.3
1.3
15.74
5.98
u/ml
0.33
14
196
7
38
1.86
0.74
1.1
1.2
—
—
—
0
0
7
38
1.86
0.74
3.9
1.8
10.71
10.66
mmol/l
—
7
38
6
106
0.56
0.73
1.2
1.5
—
—
—
0
0
5
26
1.93
0.71
1.0
1.7
—
—
—
0
0
21
152
1.40
0.70
2.0
1.9
278.55
172.36
u/ml
0.56
11
72
41
330
1.27
0.69
1.4
1.6
1167.17
1220.57
nmol/l
0.15
36
253
187
1732
1.15
0.69
3.7
3.6
30.15
0.00
estimate
0.49
40
340
9
59
1.54
0.68
1.7
1.7
—
—
—
0
0
5
91
0.54
0.68
1.0
1.2
—
1.92
—
0
9
185
1714
1.15
0.67
3.6
3.6
0.00
0.00
estimate
0.50
38
347
133
1457
0.87
0.66
3.3
3.2
78.39
71.48
nmol/l
2.14
124
1359
10
63
1.60
0.62
1.5
1.9
—
—
—
0
0
33
409
0.79
0.62
1.7
1.9
3.60
3.67
ratio
0.10
23
309
84
947
0.86
0.61
3.4
4.3
1.65
1.97
ug/l
0.36
77
859
85
749
1.17
0.60
3.4
3.7
355.53
336.31
umol/l
1.01
79
681
0
21
0.00
0.60
0.0
1.2
—
0.36
—
0
21
109
980
1.15
0.60
3.3
3.7
0.33
0.27
e6/l
0.26
89
692
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
23
175
1.33
0.59
1.4
1.6
—
—
—
0
0
264
2521
1.14
0.58
4.2
4.2
15.24
14.58
pmol/l
3.56
249
2361
8
54
1.49
0.57
2.4
1.6
—
—
—
0
0
90
801
1.16
0.57
3.5
3.3
1.02
1.02
kg/l
0.37
63
508
138
1269
1.13
0.54
3.6
3.2
0.00
0.02
estimate
0.88
34
294
22
169
1.32
0.54
1.8
1.6
—
—
—
0
0
16
213
0.74
0.51
1.3
1.3
—
—
—
0
0
13
92
1.43
0.51
1.8
2.4
—
—
—
0
0
245
2339
1.12
0.50
4.9
4.0
49.44
43.87
u/l
0.62
235
2259
14
101
1.40
0.50
1.3
1.4
226.62
307.35
ug/g
—
8
55
7
45
1.56
0.49
2.4
1.6
12.71
13.02
%
—
7
45
7
47
1.50
0.47
1.3
1.3
—
—
—
0
0
36
426
0.83
0.46
3.4
2.6
346.47
358.44
nmol/l
0.16
36
406
23
286
0.79
0.46
1.0
1.1
—
—
—
0
0
5
83
0.60
0.46
2.2
1.1
—
62.41
—
0
22
100
1089
0.89
0.44
1.4
1.7
1.12
2.28
u/ml
0.98
26
253
5
31
1.62
0.43
1.0
1.2
—
—
—
0
0
5
31
1.62
0.43
1.6
4.3
1.86
3.11
nmol/l
—
5
31
292
2830
1.12
0.42
4.3
3.9
1.30
1.28
mmol/l
0.13
282
2672
0
15
0.00
0.41
0.0
1.2
—
89.14
—
0
15
0
15
0.00
0.41
0.0
1.2
—
28.18
—
0
15
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
2.1
—
15.57
—
0
11
308
2998
1.12
0.39
5.0
4.9
1.89
1.88
mu/l
0.04
293
2824
0
19
0.00
0.39
0.0
4.5
—
78.62
—
0
19
0
19
0.00
0.39
0.0
3.1
—
152.12
—
0
19
18
142
1.28
0.39
2.5
1.8
—
—
—
0
0
29
243
1.21
0.38
1.3
1.6
—
—
—
0
0
353
3469
1.16
0.36
14.2
11.4
30.25
28.32
u/l
0.67
345
3404
5
78
0.64
0.36
1.0
1.3
—
—
—
0
0
5
78
0.64
0.36
1.2
1.6
—
—
—
0
0
77
837
0.90
0.33
4.0
4.3
4.59
29.76
mg/mmol
0.68
50
560
17
137
1.25
0.32
2.6
1.9
73.50
117.16
au/ml
—
7
55
7
53
1.33
0.31
1.3
1.4
—
—
—
0
0
99
1057
0.91
0.30
1.7
1.9
—
—
—
0
0
11
84
1.32
0.30
4.6
2.6
—
—
—
0
0
18
148
1.23
0.29
1.1
1.1
1.39
1.48
g/l
1.26
18
148
79
731
1.10
0.29
1.6
1.5
19.33
20.45
nmol/l
0.39
74
629
13
161
0.80
0.28
1.3
1.3
—
—
—
0
0
9
117
0.76
0.28
1.7
1.5
—
0.05
—
0
18
12
149
0.80
0.26
1.2
1.3
199.50
257.01
miu/ml
—
6
71
5
71
0.70
0.26
1.0
1.0
6.38
7.43
kpa
—
5
61
126
1323
0.93
0.26
2.0
2.0
1.48
1.39
mmol/l
0.60
110
1161
18
151
1.20
0.25
1.1
1.2
0.83
0.91
g/l
1.26
18
151
24
275
0.86
0.24
1.6
1.3
98.92
138.60
u/ml
—
8
98
9
77
1.17
0.24
8.6
1.9
2.80
2.90
g/l
—
9
72
6
81
0.74
0.24
1.0
1.4
—
—
—
0
0
11
136
0.80
0.23
1.6
1.8
174.18
241.04
pmol/l
1.63
11
129
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
14
167
0.83
0.22
1.5
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
361.00
—
0
6
0
12
0.00
0.21
0.0
4.6
—
24.25
—
0
12
0
12
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
15
176
0.85
0.20
1.5
1.8
39.40
37.75
nmol/l
0.09
15
171
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
11
90
1.23
0.19
2.0
1.4
—
—
—
0
0
5
70
0.71
0.17
1.0
1.0
3.10
3.12
kpa
—
5
60
245
2401
1.05
0.16
4.9
4.5
10.40
9.00
mm/h
0.75
230
2275
8
69
1.16
0.16
1.8
1.5
46.53
49.93
ug/l
—
8
69
8
71
1.13
0.16
9.5
1.9
10.60
10.15
g/l
—
8
65
8
73
1.10
0.16
9.5
2.2
1.44
1.14
g/l
—
8
67
10
83
1.21
0.15
1.3
1.5
—
—
—
0
0
9
81
1.11
0.15
8.6
1.9
4.24
4.35
g/l
—
9
76
9
81
1.11
0.15
8.6
1.9
7.06
7.15
g/l
—
9
76
9
81
1.11
0.15
8.6
1.9
3.04
3.57
g/l
—
9
76
274
2774
0.96
0.13
5.5
5.5
36.98
38.37
mmol/mol
2.63
261
2654
289
2851
1.05
0.13
4.5
4.2
5.72
5.80
mmol/l
0.68
274
2669
266
2694
0.96
0.13
3.5
3.6
—
—
—
0
0
58
609
0.94
0.13
2.4
2.1
—
—
—
0
0
54
568
0.94
0.12
1.3
1.3
19.00
26.13
iu/ml
0.66
11
154
111
1144
0.96
0.12
2.1
1.9
92.82
95.15
pmol/l
0.22
75
597
15
167
0.89
0.11
1.0
1.2
0.19
2.44
u/ml
—
10
119
20
216
0.92
0.09
2.1
1.7
0.29
0.30
mg/l
—
10
101
6
55
1.09
0.09
1.8
1.2
—
—
—
0
0
6
58
1.03
0.08
1.8
1.1
—
—
—
0
0
7
64
1.09
0.08
10.7
1.9
0.00
0.00
g/l
—
7
57
97
945
1.03
0.08
3.0
2.9
0.00
0.01
estimate
0.74
33
274
8
93
0.86
0.07
1.3
1.3
—
—
—
0
0
59
608
0.96
0.06
2.5
3.8
1.65
1.65
e6/l
0.00
33
293
37
384
0.96
0.05
1.4
1.5
—
—
—
0
0
11
100
1.10
0.05
1.4
1.7
22.32
23.22
ng/l
0.06
11
100
15
142
1.06
0.02
1.5
1.4
—
—
—
0
0
11
116
0.95
0.01
1.3
1.1
—
—
—
0
0
11
115
0.95
0.00
1.3
1.1
—
—
—
0
0
66
658
1.00
0.00
2.4
2.3
—
—
—
0
0
64
641
1.00
0.00
2.6
3.5
0.81
0.69
e6/l
0.22
36
324
19
191
0.99
0.00
1.2
1.2
0.20
2.72
u/ml
2.84
13
131
10
95
1.05
0.00
1.6
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
11.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
7.1
4.6
321.86
386.09
umol/l
—
7
66
7
79
0.88
-0.00
1.1
1.5
—
—
—
0
0
5
58
0.86
-0.00
1.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
84
0.95
-0.00
1.8
1.7
—
—
—
0
0
9
90
1.00
-0.00
1.3
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_COARCTATION_OF_THE_AORTA – Coarctation of the aorta
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).