bronchitis: An acute or chronic inflammatory process affecting the bronchi. [database_cross_reference: NCIT:C2911]
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1705 |
4. Check minimum number of eventsNone |
1705 |
5. Include endpointsNone |
1705 |
6. Filter based on genotype QC (FinnGen only) |
1541 |
Control definitions (FinnGen only)
- Control exclude
- J10_LOWCHRON
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J40-J47
- Name in latin
- Bronchitis chronica non specificata
Similar endpoints
↥List of similar endpoints to
Unspecified chronic bronchitis
based on the number of shared cases.
Similar with more cases:
- Chronic lower respiratory diseases
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
- Diseases of the respiratory system
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18442 | 6735 | 11129 |
| Only index persons | 8641 | 4155 | 4486 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.28 | 0.19 | 0.31 |
| Only index persons | 0.16 | 0.15 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 61.97 | 59.69 | 63.16 |
| Only index persons | 54.81 | 54.34 | 55.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1541 | 573 | 968 |
| Unadjusted period prevalence (%) | 0.35 | 0.20 | 0.44 |
| Median age at first event (years) | 57.50 | 54.30 | 59.40 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1587
- Matched controls
- 15866
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R03BB01
ATC
ipratropium bromide; inhalant
19.5
321.1
263
160
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
87.4
307.7
528
90
R03DA04
ATC
theophylline; systemic, rectal
19.1
307.7
315
203
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
147.0
307.7
227
18
R03BB04
ATC
tiotropium bromide; inhalant
30.6
307.7
449
202
J45.1
ICD-10 Finland
Nonallergic asthma
130.7
307.7
185
16
R03AC12
ATC
salmeterol; inhalant
65.6
307.7
201
35
J42
ICD-10 Finland
Unspecified chronic bronchitis
2658.9
307.7
1088
13
J45.0
ICD-10 Finland
Predominantly allergic asthma
87.5
307.7
172
22
J45.9
ICD-10 Finland
Asthma, unspecified
41.7
307.7
506
176
R03AK03
ATC
[U] fenoterol and ipratropium bromide
17.9
307.7
344
242
49109
ICD-8 Finland
Chronic bronchitis, Unspecified
+∞
307.7
342
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
307.7
608
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
14.9
307.7
426
381
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
118.5
307.7
233
23
R03AC02
ATC
salbutamol; inhalant
7.0
306.3
1111
3987
R03BA01
ATC
beclometasone; inhalant
10.2
285.8
365
452
R03BA02
ATC
budesonide; inhalant
8.7
279.7
418
627
R03BA05
ATC
fluticasone; inhalant
8.1
274.7
441
717
R03DC03
ATC
montelukast; oral
9.2
254.4
352
479
UGC12
NOMESCO Finland
Flexible bronchoscopy
8.7
251.2
364
523
R03AK07
ATC
formoterol and budesonide; inhalant
6.3
213.2
439
906
H02AB06
ATC
prednisolone; systemic
4.8
207.8
999
4121
R03AC13
ATC
formoterol; inhalant
28.1
202.9
139
54
4919X
ICD-9 Finland
Chronic bronchitis, Unspecified chronic bronchitis
+∞
199.2
187
*
R96
ICPC
Asthma
14.6
192.4
180
138
J45
ICD-10 Finland
Asthma
14.9
184.3
170
127
R03AC03
ATC
terbutaline; inhalant
6.6
155.3
282
506
R03AK08
ATC
formoterol and beclometasone; inhalant
27.6
154.5
106
41
J47
ICD-10 Finland
Bronchiectasis
795.1
149.7
145
*
R03BA08
ATC
ciclesonide; inhalant
9.6
148.1
184
214
R95
ICPC
Chron obstructive pulmonary disease
30.2
141.4
94
33
H02AB04
ATC
methylprednisolone; systemic
4.7
127.5
351
904
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
178.2
126.4
131
8
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
4.0
124.7
466
1504
J96.1
ICD-10 Finland
Chronic respiratory failure
17.7
114.9
95
57
J01MA14
ATC
moxifloxacin; systemic
5.3
113.5
259
568
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
16.1
107.5
93
61
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
+∞
106.5
101
*
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
165.4
103.6
108
7
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
8.2
101.9
141
186
J45.8
ICD-10 Finland
Mixed asthma
524.9
100.7
99
*
R05
ICD-10 Finland
Cough
3.5
97.4
442
1594
R04.2
ICD-10 Finland
Haemoptysis
7.4
94.0
142
207
XG474
NOMESCO Finland
Exhalation nntrogen oxide
20.0
91.5
71
37
49300
ICD-8 Finland
Asthma, bronchiale
+∞
90.5
86
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.8
87.1
144
231
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
87.1
673
3257
H02AB07
ATC
prednisone; oral
3.8
86.5
311
957
R03BB02
ATC
oxitropium bromide; inhalant
28.1
84.0
57
21
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
21.8
81.7
61
29
J01FA06
ATC
roxithromycin; oral
2.7
81.7
723
3723
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
48.4
80.3
47
10
R06.0
ICD-10 Finland
Dyspnoea
2.9
80.3
538
2396
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
9.4
77.6
95
107
R06.2
ICD-10 Finland
Wheezing
7.6
76.9
112
156
R03AK11
ATC
formoterol and fluticasone; inhalant
21.1
75.2
57
28
J46
ICD-10 Finland
Status asthmaticus
258.5
73.0
74
*
J01AA02
ATC
doxycycline; systemic
3.1
72.5
1284
9121
J41.0
ICD-10 Finland
Simple chronic bronchitis
41.1
72.4
44
11
J01FA09
ATC
clarithromycin; systemic
2.8
71.9
510
2319
49099
ICD-8 Finland
Bronchitis, unspecified
+∞
67.2
64
*
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
19.2
65.9
52
28
XG410
NOMESCO Finland
Flow-volume spirometry
7.4
65.7
98
140
R03DC01
ATC
zafirlukast; oral
24.2
65.6
47
20
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
+∞
65.0
62
*
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
+∞
64.0
61
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.5
62.3
245
790
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
8.0
56.4
78
102
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
7.8
55.0
78
105
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
102.1
54.2
59
6
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
+∞
53.4
51
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.0
51.1
259
967
R03DA05
ATC
aminophylline; systemic, rectal
15.6
50.4
44
29
R02
ICPC
Shortness of breath/dyspnoea
3.0
49.5
247
913
J01MA12
ATC
levofloxacin; systemic
2.5
49.3
382
1771
R05CB01
ATC
acetylcysteine; inhalant, oral
8.6
48.6
63
76
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
48.5
761
4740
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
171.9
48.1
50
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
7.7
47.3
67
90
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.4
46.4
95
186
J01FA10
ATC
azithromycin; systemic
2.1
45.2
767
4882
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.1
44.9
128
329
R03BC03
ATC
nedocromil; inhalant
4.1
44.4
129
336
TGC00
NOMESCO Finland
Bronchial lavation
6.7
44.1
71
110
R01AD08
ATC
fluticasone; nasal
2.3
41.4
399
2021
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.9
40.9
129
356
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
40.1
132
375
49101
ICD-8 Finland
Chronic bronchitis, Nonpurulenta (simplex)
+∞
39.7
38
*
J01FA15
ATC
telithromycin; oral
3.2
38.0
161
538
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.1
36.3
456
2549
48609
ICD-8 Finland
Pneumonia, unspecified
7.9
36.3
50
65
R01AD09
ATC
mometasone; nasal
2.0
35.3
588
3631
51899
ICD-8 Finland
Bronchiectasis
+∞
34.5
33
*
J01DA01
ATC
[U] cefalexin
1.9
33.7
976
7202
G47.3
ICD-10 Finland
Sleep apnoea
2.2
33.3
343
1767
SPAT1059
SPAT
Spirometry at the office
4.5
33.2
82
188
J20
ICD-10 Finland
Acute bronchitis
2.9
32.8
167
619
R29
ICPC
Respiratory symptom/complaint other
3.4
31.6
117
359
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
+∞
31.3
30
*
J43.9
ICD-10 Finland
Emphysema, unspecified
47.3
30.7
37
8
R05DA20
ATC
opium alkaloids and derivatives - combinations
2.0
30.3
389
2171
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.5
30.2
106
314
A01AB09
ATC
miconazole; local oral
2.8
29.8
161
615
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
29.6
742
5153
R05
ICPC
Cough
2.1
29.3
345
1862
XQ800
NOMESCO Finland
Prick test
3.8
29.2
93
258
C03CA01
ATC
furosemide; systemic
1.8
29.0
659
4431
A02BC01
ATC
omeprazole; systemic
1.9
29.0
467
2814
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.7
28.9
68
150
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.5
28.8
102
304
R05CB02
ATC
bromhexine; systemic
5.6
28.8
55
101
R03DA54
ATC
theophylline, combinations excl. psycholeptics; systemic
6.5
27.9
46
73
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
27.4
580
3802
A02BA02
ATC
ranitidine; systemic
2.0
27.2
363
2046
N02AX02
ATC
tramadol; systemic, rectal
1.8
27.1
673
4623
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
26.9
523
3334
J37.0
ICD-10 Finland
Chronic laryngitis
4.4
26.6
67
156
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
6.6
26.5
43
67
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.6
26.3
64
145
XG480
NOMESCO Finland
Histamine provocation of respiratroy tract
10.5
26.3
29
28
48509
ICD-8 Finland
Bronchopneumonia, unspecified
8.2
24.8
33
41
R03AC04
ATC
fenoterol; inhalant
253.9
24.7
25
*
1240
FHL
Bronchoscopy
5.5
24.6
48
90
A02BC05
ATC
esomeprazole; systemic
1.8
24.4
588
3971
R03CC02
ATC
salbutamol; systemic
4.5
24.4
60
137
R05FB02
ATC
cough suppressants and expectorants; systemic
1.8
24.1
590
4000
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.0
24.0
52
107
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.9
23.8
71
188
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.0
23.5
108
377
GX1E5, ,
SPAT
9.8
23.3
27
28
49102
ICD-8 Finland
Chronic bronchitis, Purulenta
+∞
23.0
22
*
XG460
NOMESCO Finland
Short time oxymetry
5.4
22.8
45
85
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
4.6
22.8
55
124
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
22.7
282
1539
J32.4
ICD-10 Finland
Chronic pansinusitis
9.5
22.7
27
29
SPAT1058
SPAT
PEF monitoring instruction
3.0
22.3
100
344
GD1AA, ,
SPAT
2.2
22.3
205
998
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
+∞
21.9
21
*
J98.0
ICD-10 Finland
Diseases of bronchus, not elsewhere classified
29.5
21.9
29
10
R78
ICPC
Acute bronchitis/bronchiolitis
5.8
21.7
40
71
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.4
21.7
156
684
A07AA02
ATC
nystatin; oral
2.9
21.2
103
371
Y0499
ICD-8 Finland
Investigation of respiratory system
5.9
21.1
38
66
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
+∞
20.9
20
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.5
20.6
72
213
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
17.2
20.5
32
19
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
20.5
182
873
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
5.2
20.3
42
83
UDC00
NOMESCO Finland
Ear microscopy
2.6
20.2
124
504
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
7.4
20.0
29
40
R06AE07
ATC
cetirizine; oral
1.7
19.8
526
3603
4910A
ICD-9 Finland
Chronic bronchitis, Simple chronic bronchitis
+∞
19.8
19
*
4900A
ICD-9 Finland
Bronchitis, not specified as acute or chronic[BRONCHITIS NUD]
+∞
19.8
19
*
J02AC01
ATC
fluconazole; systemic
1.7
19.6
454
2996
R03AK
ATC
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
202.4
19.6
20
*
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
6.1
19.5
34
57
A02BC03
ATC
lansoprazole; oral
1.7
19.4
442
2904
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
8.4
19.3
25
30
R01AD11
ATC
triamcinolone; nasal
2.5
19.1
123
511
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
6.3
19.0
32
52
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
18.9
446
2954
J31.0
ICD-10 Finland
Chronic rhinitis
2.6
18.8
115
466
R03AC18
ATC
indacaterol; inhalant
70.7
18.7
21
*
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.5
18.7
118
486
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
18.6
425
2789
R28
ICPC
Limited function/disability (R)
6.3
18.5
31
50
R81
ICPC
Pneumonia
3.3
18.4
69
213
A01AB04
ATC
amphotericin B; local oral
2.8
18.2
92
339
J01DC02
ATC
cefuroxime; systemic
3.0
18.0
82
285
XG405
NOMESCO Finland
Education on PEF monitoring
13.9
17.8
30
22
A02BC02
ATC
pantoprazole; systemic
1.6
17.8
966
7820
R03BB07
ATC
umeclidinium bromide; inhalant
37.1
17.6
22
6
XG466
NOMESCO Finland
Sleep oxymetry
4.2
17.6
47
115
R05FA02
ATC
opium derivatives and expectorants; systemic
1.6
17.2
555
3963
WZC30
NOMESCO Finland
Teaching
1.9
17.2
231
1289
SPAT1263
SPAT
Sampling
1.6
17.1
561
4024
R01AD12
ATC
fluticasone furoate; nasal
1.8
17.0
325
2022
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
17.0
110
459
R04
ICPC
Breathing problem other
3.3
16.9
64
199
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
+∞
16.7
16
*
J01FA01
ATC
erythromycin; systemic
2.1
16.7
167
838
C01AA05
ATC
digoxin; systemic
1.9
16.6
221
1228
J01DA06
ATC
[U] cefuroxime
2.0
16.6
207
1125
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
13.5
16.5
28
21
J01DA09
ATC
[U] cefadroxil
1.7
16.4
368
2393
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
16.3
310
1925
R01AD58
ATC
fluticasone, combinations; nasal
1.9
16.2
249
1450
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
15.9
312
1951
3472A
ICD-9 Finland
Cataplexy and narcolepsy[OBSTRUKTIIVINEN UNIAPNEA]
4.7
15.9
37
81
N05CF01
ATC
zopiclone; oral
1.6
15.7
523
3747
N05CD07
ATC
temazepam; oral
1.8
15.6
246
1441
R03CC03
ATC
terbutaline; systemic
6.1
15.6
27
45
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.2
15.3
62
201
N03AX12
ATC
[U] gabapentin; oral
1.9
15.1
221
1264
R74
ICPC
Upper respiratory infection acute
1.7
15.1
333
2149
N03AX16
ATC
[U] pregabalin
1.7
14.9
308
1953
N06AX21
ATC
duloxetine; oral
2.1
14.6
153
781
N05BA01
ATC
diazepam; systemic, rectal
1.9
14.5
199
1115
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
5.4
14.2
28
53
R06AX13
ATC
loratadine; oral
2.0
14.2
162
852
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
14.1
107
479
R51.80
ICD-10 Finland
Headache
1.9
14.1
189
1050
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
6.5
14.1
23
36
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
14.6
14.1
23
16
A02BA03
ATC
famotidine; systemic
2.6
13.9
81
321
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
24.0
13.8
19
8
P01AB01
ATC
metronidazole; oral, rectal
1.5
13.6
503
3666
4911A
ICD-9 Finland
Chronic bronchitis, Mucopurulent chronic bronchitis
+∞
13.6
13
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
13.6
593
4480
J01FF01
ATC
clindamycin; systemic
1.6
13.5
360
2430
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
13.3
349
2345
R06AX27
ATC
desloratadine; oral
1.7
13.2
284
1814
Z72.0
ICD-10 Finland
Tobacco use
4.0
13.2
37
94
M03BC51
ATC
orphenadrine, combinations; systemic
1.6
13.0
328
2182
J01CA04
ATC
amoxicillin; systemic
1.5
12.9
1072
9186
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
19.2
12.9
19
10
N05BA04
ATC
oxazepam; oral
1.6
12.9
379
2616
R09.3
ICD-10 Finland
Abnormal sputum
4.9
12.9
28
58
UJF32
NOMESCO Finland
Coloscopy
1.6
12.8
374
2580
E66.00
ICD-10 Finland
Metabolic syndrome
2.5
12.7
78
318
N06AA12
ATC
doxepin; systemic
2.4
12.6
89
387
R01AD05
ATC
budesonide; nasal
2.3
12.6
92
406
49302
ICD-8 Finland
Asthma, Rhinitis allergica cum asthmate bronchiali
+∞
12.5
12
*
49309
ICD-8 Finland
Asthma, Unspecified
+∞
12.5
12
*
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
+∞
12.5
12
*
A03CA02
ATC
clidinium and psycholeptics; oral
2.2
12.5
103
478
C07AB07
ATC
bisoprolol; oral
1.5
12.4
761
6119
M54.5
ICD-10 Finland
Low back pain
1.5
12.4
443
3191
L03
ICPC
Low back symptom/complaint
1.6
12.4
350
2390
N06AA09
ATC
amitriptyline; systemic
2.0
12.3
141
742
ZY010
NOMESCO Finland
Hospital outpatient
2.8
12.3
63
234
C08DA01
ATC
verapamil; systemic
2.4
12.1
82
349
R05DA01
ATC
ethylmorphine; oral
2.1
12.1
115
565
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
12.0
427
3069
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.1
11.9
50
166
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.9
11.9
55
193
R05CB03
ATC
carbocisteine; oral
3.3
11.8
45
141
A02BA04
ATC
nizatidine; systemic
2.0
11.8
137
725
Q32.21
ICD-10 Finland
Secondary congenital bronchomalacia
65.4
11.6
13
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.9
11.5
139
746
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.6
11.4
64
249
SPAT1257
SPAT
Teaching of medicine inhalation technique
3.5
11.4
39
114
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.0
11.4
50
171
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.9
11.3
52
182
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
11.2
482
3596
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
4.1
11.2
30
74
R03AL04
ATC
indacaterol and glycopyrronium bromide; inhalant
25.2
11.1
15
6
N06AB04
ATC
citalopram; systemic
1.6
11.1
284
1892
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.0
11.0
48
163
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
11.0
244
1566
R52.2
ICD-10 Finland
Other chronic pain
2.8
11.0
55
202
R06.5
ICD-10 Finland
Mouth breathing
2.1
10.9
111
560
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
10.8
379
2707
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
12.0
10.8
19
16
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.5
10.7
36
104
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
5.6
10.7
20
36
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
21.6
10.7
15
7
A06AD11
ATC
lactulose; oral
1.6
10.6
290
1961
R13
ICD-10 Finland
Dysphagia
2.1
10.6
107
539
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
8.6
10.5
22
26
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.2
10.5
91
431
WX780
NOMESCO Finland
Remote monitoring CPAP
2.6
10.5
61
242
R10.0
ICD-10 Finland
Acute abdomen
2.9
10.5
50
179
J43.8
ICD-10 Finland
Other emphysema
+∞
10.4
10
*
R01AD01
ATC
beclometasone; nasal
1.8
10.4
175
1041
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
3.0
10.3
45
153
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
3.2
10.3
40
127
R03AL11
ATC
formoterol, glycopyrronium bromide and budesonide; inhalant
18.9
10.3
15
8
ZXE00
NOMESCO Finland
One hour or less
1.4
10.1
510
3912
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.0
536
4154
J01DA08
ATC
[U] cefaclor
2.0
10.0
107
550
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
10.0
119
635
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
10.0
327
2299
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.0
10.0
113
593
J01EA01
ATC
trimethoprim; systemic
1.5
10.0
360
2584
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
10.0
233
1515
C08DB01
ATC
diltiazem; oral
2.0
9.9
115
608
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
9.9
80
369
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
9.8
139
785
R03BB06
ATC
glycopyrronium bromide; inhalant
26.2
9.8
13
5
G44.2
ICD-10 Finland
Tension-type headache
1.8
9.6
150
873
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
9.6
114
608
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.3
9.6
74
335
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
9.6
136
769
C01DA14
ATC
isosorbide mononitrate; oral
1.5
9.6
334
2378
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
11.4
9.6
17
15
78310
ICD-8 Finland
Symptoms referable to respiratory system, Haemoptysis
10.1
9.5
18
18
WX723
NOMESCO Finland
CPAP therapy
2.5
9.5
58
236
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.2
9.5
36
113
E66.01
ICD-10 Finland
Obesity due to excess calories
2.1
9.4
93
464
N06AX11
ATC
mirtazapine; oral
1.5
9.4
429
3221
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
8.1
9.3
20
25
A03
ICPC
Fever
1.7
9.3
177
1090
M48.0
ICD-10 Finland
Spinal stenosis
1.7
9.3
185
1154
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.3
9.1
67
298
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
15.7
9.0
14
9
J15.8
ICD-10 Finland
Other bacterial pneumonia
7.1
9.0
21
30
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
9.0
54
218
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.9
368
2707
A03FA02
ATC
cisapride; oral, rectal
1.9
8.8
118
655
A01AB10
ATC
natamycin; local oral
2.8
8.7
42
152
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.4
8.6
30
89
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.6
489
3808
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.6
8.6
48
187
R05DB20
ATC
other cough suppressants - combinations
2.1
8.6
76
364
J98.1
ICD-10 Finland
Pulmonary collapse
8.3
8.6
18
22
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
2.9
8.6
38
131
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.6
8.5
48
188
4130X
ICD-9 Finland
Angina pectoris, Angina decubitus[ANGINA PECTORIS (""""EFFORT ANGINA""""),MÄÄRITTELEMÄT]
2.3
8.5
60
262
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.6
8.4
27
76
348
Kela drug reimbursment
Roflumilast
+∞
8.3
8
*
C03DA01
ATC
spironolactone; oral
1.6
8.3
191
1234
R03BA07
ATC
mometasone; inhalant
10.8
8.3
15
14
D07AC13
ATC
mometasone; topical
1.4
8.3
360
2671
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
8.2
82
411
R05DB05
ATC
pentoxyverine; oral, rectal
2.4
8.2
55
234
UDM02
NOMESCO Finland
Sinoscopy
3.4
8.2
29
87
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
8.2
170
1070
SXC05
NOMESCO Finland
Other oral or dental procedure
2.2
8.2
70
331
SPAT1260
SPAT
Consultation of another employee
1.6
8.2
218
1460
L01
ICPC
Neck symptom/complaint
1.6
8.2
176
1120
N06AX03
ATC
mianserin; oral
2.2
8.1
70
332
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
8.1
519
4117
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
4.8
8.1
18
38
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
4.8
8.1
18
38
48601
ICD-8 Finland
More specifically, unspecified pneumonia and the pleural irritation caused by it
8.2
8.1
17
21
I50.0
ICD-10 Finland
Congestive heart failure
1.7
8.0
152
934
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.5
8.0
47
188
R11
ICD-10 Finland
Nausea and vomiting
1.8
8.0
119
683
Z01.9
ICD-10 Finland
Special examination, unspecified
2.0
8.0
83
423
Z00.8
ICD-10 Finland
Other general examinations
1.9
8.0
100
544
R24
ICPC
Haemoptysis
7.3
8.0
18
25
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
7.9
203
1347
D06
ICPC
Abdominal pain localized other
1.9
7.9
103
567
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.9
179
1153
R053, ,
ICD-10 Finland
2.8
7.9
39
143
WX199
NOMESCO Finland
Other local analgesia
2.3
7.9
56
245
N06AG02
ATC
moclobemide; oral
2.3
7.9
56
245
R06AE09
ATC
levocetirizine; oral
1.7
7.9
131
777
M04AA01
ATC
allopurinol; systemic
1.5
7.8
227
1548
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
7.8
156
972
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
7.8
124
725
A03DA02
ATC
pitofenone and analgesics; systemic
2.8
7.8
38
138
R49.01
ICD-10 Finland
Functional dysphonia
2.8
7.8
38
138
S82.4
ICD-10 Finland
Fracture of fibula alone
3.5
7.8
26
75
D07AA02
ATC
hydrocortisone; topical
1.6
7.8
169
1076
K59.0
ICD-10 Finland
Constipation
1.9
7.8
95
512
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.8
7.8
37
133
E66.9
ICD-10 Finland
Obesity, unspecified
2.7
7.8
40
150
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.0
7.7
81
414
J41.8
ICD-10 Finland
Mixed simple and mucopurulent chronic bronchitis
45.2
7.7
9
*
4660A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchitis
4.4
7.7
19
44
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
5.9
7.7
20
34
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.6
427
3307
J01CA02
ATC
pivampicillin; oral
2.7
7.6
40
152
50609
ICD-8 Finland
Chronic laryngitis, Unspecified
25.1
7.6
10
*
T82
ICPC
Obesity
2.6
7.5
42
164
7863A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Haemoptysis
7.1
7.5
17
24
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
7.5
315
2319
RK320, ,
NOMESCO Finland
4.4
7.4
18
41
J01GB01
ATC
tobramycin; inhalant, parenteral
80.4
7.4
8
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.3
7.4
27
83
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
7.4
301
2202
M03BX02
ATC
tizanidine; oral
1.3
7.3
700
5886
D01
ICPC
Abdominal pain/cramps general
1.7
7.3
137
840
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
7.3
127
763
H02AB09
ATC
hydrocortisone; systemic
3.1
7.3
29
94
GX2C5
NOMESCO Finland
Short-lasting oximetry
10.9
7.3
13
12
R03DX07
ATC
roflumilast; oral
+∞
7.3
7
*
4939A
ICD-9 Finland
Asthma, unspecified[ASTHMA ALIA DEFINITA SINE EXACERBATIONE]
+∞
7.3
7
*
49209
ICD-8 Finland
Emphysema, Unspecified
+∞
7.3
7
*
J43.2
ICD-10 Finland
Centrilobular emphysema
+∞
7.3
7
*
C05AA08
ATC
fluocortolone; rectal, topical
1.6
7.3
171
1111
N03AX09
ATC
lamotrigine; oral
2.4
7.2
46
192
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
3.0
7.2
30
100
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
7.2
507
4069
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
7.2
182
1204
N06AX16
ATC
venlafaxine; oral
1.7
7.1
139
861
R03AC19
ATC
olodaterol
30.1
7.1
9
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.1
7.1
64
309
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.2
7.1
59
276
R05CA10
ATC
expectorants - combinations
2.9
7.1
33
117
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
7.1
369
2816
M01AE02
ATC
naproxen; oral, rectal
1.3
7.1
689
5799
R07.3
ICD-10 Finland
Other chest pain
1.7
7.1
140
871
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
2.9
7.1
32
112
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.5
7.1
205
1398
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.0
7.1
77
400
5110B
ICD-9 Finland
Pleurisy, Without mention of effusion or current tuberculosis[PLEURA-ADHEESIOT]
8.8
7.0
14
16
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
7.0
456
3614
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
7.0
82
437
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.3
7.0
25
76
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
6.9
70
354
R4110, ,
SPAT
1.6
6.9
165
1076
J20.0
ICD-10 Finland
Acute bronchitis due to Mycoplasma pneumoniae
4.0
6.9
19
48
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.9
221
1541
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
3.5
6.8
23
67
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.5
6.8
23
67
N41.9
ICD-10 Finland
Inflammatory disease of prostate, unspecified
3.3
6.8
25
77
L04AA01
ATC
[U] ciclosporin
3.8
6.8
20
53
T78.4
ICD-10 Finland
Allergy, unspecified
2.5
6.8
41
167
J01MA01
ATC
ofloxacin; systemic
1.7
6.8
132
818
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.3
6.8
50
223
Z01.2
ICD-10 Finland
Dental examination
1.4
6.8
492
3961
R06AX22
ATC
ebastine; oral
1.6
6.8
167
1098
R03BB05
ATC
aclidinium bromide; inhalant
40.2
6.8
8
*
R03DA74
ATC
theophylline, combinations with psycholeptics; systemic
40.2
6.8
8
*
E000001, ,
ATC
1.5
6.8
232
1639
D07XC01
ATC
betamethasone; topical
1.6
6.7
162
1058
D07AC01
ATC
betamethasone; topical
1.4
6.7
451
3585
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.5
6.7
22
63
N05AL01
ATC
sulpiride; systemic
3.5
6.7
22
63
NG1AD
NOMESCO Finland
Knee CT examination
3.2
6.7
25
78
N04BC05
ATC
pramipexole; oral
1.8
6.7
103
598
51900
ICD-8 Finland
Other diseases of respiratory system, Atelectasis pulmonis
22.6
6.7
9
*
L08
ICPC
Shoulder symptom/complaint
1.5
6.7
263
1909
XFE00
NOMESCO Finland
Epicardial ultrasonography
2.5
6.6
39
157
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
5.9
6.6
17
29
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
5.5
6.6
18
33
GX1C5, ,
SPAT
12.3
6.6
11
9
Y0399
ICD-8 Finland
Investigation of circulatory system
3.2
6.6
25
79
R06AX26
ATC
fexofenadine; oral
2.1
6.5
63
313
5645A
ICD-9 Finland
Functional digestive disorders, not elsewhere classified, Functional diarrhoea
10.1
6.5
12
12
J18.8
ICD-10 Finland
Other pneumonia, organism unspecified
6.9
6.5
15
22
A46
ICD-10 Finland
Erysipelas
1.5
6.5
200
1381
R52.9
ICD-10 Finland
Pain, unspecified
1.7
6.5
123
757
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
6.2
6.5
16
26
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
2.6
6.5
37
147
A02BC04
ATC
rabeprazole; oral
1.8
6.5
98
567
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.4
227
1612
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
3.2
6.4
24
75
L04AA06
ATC
mycophenolic acid; systemic
3.2
6.4
24
75
J14
ICD-10 Finland
Pneumonia due to Haemophilus influenzae
70.1
6.4
7
*
J92.9
ICD-10 Finland
Pleural plaque without asbestos
3.4
6.4
22
65
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
6.4
120
736
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
6.4
256
1862
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.4
214
1503
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.5
6.4
38
154
I45.9
ICD-10 Finland
Conduction disorder, unspecified
4.1
6.4
17
42
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
6.3
550
4536
4289X
ICD-9 Finland
Heart failure, unspecified
3.6
6.3
20
56
WX882
NOMESCO Finland
High dependency care
2.4
6.3
40
167
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
6.3
136
866
M01AH02
ATC
rofecoxib; oral
1.5
6.3
174
1174
R50.9
ICD-10 Finland
Fever, unspecified
1.5
6.3
204
1424
GX1K5
NOMESCO Finland
Diffusion capacity
9.3
6.3
12
13
30180
ICD-8 Finland
Personality disorders, Immatura
9.3
6.3
12
13
DPA30
NOMESCO Finland
Sphenotomy
9.3
6.3
12
13
J96.0
ICD-10 Finland
Acute respiratory failure
3.3
6.3
23
71
78330
ICD-8 Finland
Symptoms referable to respiratory system, Cough
18.1
6.3
9
5
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
3.9
6.3
18
47
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
6.3
208
1459
P01BA02
ATC
hydroxychloroquine; oral
1.8
6.3
91
520
4939B
ICD-9 Finland
Asthma, unspecified[ASTHMA ALIA DEFINITA CUM EXACERBATIONE]
+∞
6.3
6
*
49308
ICD-8 Finland
Asthma, Alia definita
+∞
6.3
6
*
Q89.34
ICD-10 Finland
Cartagena syndrome (immotile cilia)
+∞
6.3
6
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
6.2
160
1061
SGA03
NOMESCO Finland
Opening and preparing the root canals, complicated
1.8
6.2
96
558
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
26.8
6.2
8
*
M09AA72
ATC
quinine, combinations with psycholeptics; systemic
2.0
6.2
67
347
J01MA06
ATC
norfloxacin; oral
1.5
6.2
173
1169
WZC00, ,
SPAT
1.6
6.2
163
1087
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
3.1
6.2
25
82
L04AX01
ATC
azathioprine; systemic
2.2
6.2
48
219
UJD02
NOMESCO Finland
Gastroscopy
2.0
6.2
68
355
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.4
6.2
40
169
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
6.2
403
3186
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
6.1
84
471
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
6.1
143
928
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.1
338
2601
L30.3
ICD-10 Finland
Infective dermatitis
2.3
6.1
42
182
-1, ,
NOMESCO Finland
1.4
6.1
340
2619
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.0
6.1
60
301
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
6.1
110
669
N05BA12
ATC
alprazolam; oral
1.7
6.0
120
748
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.0
6.0
62
316
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
10.1
6.0
11
11
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
6.0
225
1616
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
226
405
6.34
123.56
1.7
1.1
151.02
204.94
u/ml
0.35
212
367
61
19
33.34
94.87
1.6
1.1
2.17
4.28
u/ml
—
36
8
72
44
17.09
86.09
4.7
2.7
—
—
—
0
0
150
373
4.34
55.11
3.2
2.4
—
—
—
0
0
97
235
4.33
36.67
1.4
1.5
—
—
—
0
0
127
377
3.57
36.13
3.3
2.6
25.02
24.41
mmol/l
1.01
127
371
205
813
2.75
35.53
3.1
2.9
10.81
11.26
g/l
0.52
190
743
56
88
6.56
34.27
5.0
2.7
—
—
—
0
0
64
118
5.61
33.34
1.3
1.1
—
—
—
0
0
170
652
2.80
31.28
1.7
1.8
1.10
1.46
g/l
1.68
156
587
146
547
2.84
28.01
1.5
1.2
—
—
—
0
0
157
651
2.57
24.62
4.7
3.4
1.51
1.64
mmol/l
0.19
128
461
70
191
3.79
22.50
1.5
1.2
414.00
267.37
titre
—
10
19
73
212
3.56
21.42
2.0
1.4
—
—
—
0
0
84
271
3.22
20.90
2.2
1.5
—
—
—
0
0
123
491
2.63
20.79
2.6
1.9
—
—
—
0
0
43
85
5.17
20.77
1.6
1.6
—
—
—
0
0
829
6353
1.64
20.21
11.2
9.5
4.52
4.15
e9/l
4.27
750
5467
63
177
3.66
19.43
2.1
1.4
—
—
—
0
0
347
2153
1.78
18.47
2.5
1.8
—
—
—
0
0
67
205
3.37
18.17
1.4
1.2
—
—
—
0
0
63
188
3.45
17.76
2.1
1.4
—
—
—
0
0
107
432
2.58
17.67
2.3
1.5
10.19
13.88
iu/ml
—
7
13
359
2296
1.73
17.03
2.5
1.6
1.00
1.46
mg/l
3.06
272
1800
72
244
3.04
16.52
6.9
4.5
2.45
2.54
mmol/l
0.11
53
152
108
460
2.45
15.93
2.4
1.8
—
—
—
0
0
48
133
3.69
15.14
2.6
1.6
—
—
—
0
0
28
50
5.68
15.10
1.7
1.7
—
—
—
0
0
28
50
5.68
15.10
1.7
1.7
—
—
—
0
0
28
50
5.68
15.10
1.7
1.7
—
—
—
0
0
28
50
5.68
15.10
1.7
1.7
—
—
—
0
0
52
156
3.41
14.58
2.3
1.4
—
—
—
0
0
73
274
2.74
13.94
2.2
1.6
—
—
—
0
0
309
2006
1.67
13.55
1.6
1.5
2.54
2.53
g/l
0.04
209
1177
219
1307
1.78
12.97
4.8
3.6
—
—
—
0
0
83
345
2.48
12.93
2.4
1.7
—
—
—
0
0
740
5915
1.47
12.49
19.0
18.6
1.29
1.35
inr
1.96
653
4975
29
66
4.46
11.93
1.9
2.3
—
—
—
0
0
57
205
2.85
11.82
1.2
1.1
2.70
4.10
—
7
26
173
997
1.82
11.47
2.4
2.1
333.82
393.48
nmol/l
4.20
152
908
34
91
3.80
11.32
1.6
1.6
—
—
—
0
0
34
91
3.80
11.32
1.6
1.6
—
—
—
0
0
34
91
3.80
11.32
1.6
1.6
—
—
—
0
0
197
1186
1.75
11.27
2.9
2.3
159.03
130.42
ug/g
0.61
152
944
27
64
4.27
10.57
3.0
1.5
—
—
—
0
0
34
96
3.60
10.50
1.2
1.1
3.12
1.76
u/ml
0.26
19
48
168
993
1.77
10.22
4.6
4.0
1.22
1.22
mmol/l
0.50
147
838
89
429
2.14
9.87
1.9
2.0
36.38
38.37
u/l
0.43
81
368
51
191
2.72
9.85
2.7
1.7
—
—
—
0
0
273
1878
1.55
9.14
3.3
2.6
19.73
22.57
%
3.62
256
1736
25
65
3.89
8.70
3.1
1.5
—
—
—
0
0
287
2019
1.51
8.63
3.2
2.5
2.29
2.24
g/l
0.79
265
1846
24
61
3.98
8.61
1.2
1.0
9.22
0.71
u/ml
0.61
13
20
27
76
3.60
8.41
3.0
1.4
—
—
—
0
0
36
124
2.95
8.15
1.3
1.4
—
—
—
0
0
508
4020
1.39
8.06
4.8
3.2
1454.76
1841.07
ng/l
1.04
455
3479
29
89
3.30
7.94
3.2
1.6
—
—
—
0
0
298
2155
1.47
7.77
3.3
2.6
11.44
12.53
umol/l
1.97
273
1988
39
147
2.69
7.51
2.8
1.6
—
—
—
0
0
948
8319
1.35
7.50
6.8
4.2
15.60
13.51
mm/h
3.20
903
7680
23
63
3.69
7.47
1.8
2.0
487.59
554.10
e6/l
0.22
17
52
472
3733
1.38
7.39
3.3
2.6
52.91
82.00
u/l
0.75
443
3432
22
59
3.77
7.36
1.2
1.1
4.76
3.43
u/ml
0.16
12
18
56
255
2.24
7.22
2.9
2.1
130.22
127.06
g/l
0.42
45
212
377
2886
1.40
7.15
3.5
2.8
6.66
5.14
e6/l
0.89
349
2642
24
70
3.46
7.12
1.3
1.0
2.45
1.98
u/ml
0.08
14
28
239
1690
1.49
6.93
1.3
1.3
8.45
12.95
u/ml
0.64
103
623
69
347
2.03
6.92
4.1
3.7
1.70
1.70
mg/l
0.02
60
313
651
5462
1.32
6.76
6.2
5.1
34.69
35.04
g/l
0.78
611
5091
729
6233
1.31
6.54
7.6
6.6
10.96
12.86
umol/l
3.69
696
5938
406
3191
1.37
6.48
4.6
3.6
0.15
0.06
estimate
0.25
172
983
67
342
2.00
6.47
1.6
1.4
292.22
278.53
ug/g
0.15
32
206
143
917
1.61
6.43
2.0
1.6
—
—
—
0
0
250
1812
1.45
6.37
1.3
1.3
43.16
34.44
iu/ml
0.34
77
547
579
4824
1.31
6.17
5.7
4.0
181.15
74.58
ng/l
0.42
434
3679
96
565
1.74
5.98
2.7
1.8
1.34
2.94
ug/l
0.88
80
487
36
147
2.48
5.96
1.6
1.4
—
—
—
0
0
19
54
3.55
5.88
1.2
1.1
0.15
0.67
u/ml
—
10
13
36
148
2.47
5.88
1.6
1.4
—
—
—
0
0
15
26
5.81
5.84
1.3
1.4
—
—
—
0
0
207
2834
0.69
5.78
3.5
3.4
0.76
0.86
ug/l
0.98
143
1911
424
3410
1.33
5.72
2.8
2.2
2.82
2.88
mg/l
0.22
373
2892
339
2644
1.36
5.59
1.9
1.8
21132529.76
19320727.63
pmol/l
0.03
265
2148
91
1472
0.59
5.52
8.1
7.8
—
—
—
0
0
222
1616
1.43
5.51
2.4
1.7
—
—
—
0
0
211
1522
1.45
5.50
2.5
1.7
—
—
—
0
0
35
147
2.41
5.48
1.6
1.4
—
—
—
0
0
800
7027
1.28
5.47
7.4
5.0
6.83
6.85
mmol/l
0.09
767
6695
1096
11804
0.77
5.35
40.9
26.0
253.65
240.62
e9/l
7.87
1084
11500
1097
11813
0.77
5.34
41.4
26.2
132.94
133.25
g/l
0.27
1084
11623
1097
11809
0.77
5.29
41.9
26.5
39.84
39.67
%
0.46
1085
11610
1097
11809
0.77
5.29
40.8
26.0
4.43
4.41
e12/l
0.56
1081
11463
1097
11807
0.77
5.27
40.7
26.0
91.61
91.58
fl
0.10
1087
11619
1098
11812
0.77
5.22
40.9
26.1
7.70
6.77
e9/l
2.19
1079
11459
23
80
2.90
5.20
1.3
1.4
100.35
93.69
umol/l
0.24
23
80
661
5713
1.27
5.01
3.2
2.6
—
—
—
0
0
29
118
2.48
4.89
1.1
1.3
0.21
0.19
nmol/l
0.54
22
93
791
8802
0.80
4.72
33.5
21.4
14.03
13.77
%
5.23
786
8663
152
1063
1.48
4.66
3.8
3.0
168.11
255.25
ng/l
2.16
135
970
58
320
1.84
4.54
1.4
1.3
—
—
—
0
0
209
1559
1.39
4.51
4.6
4.4
249.06
255.23
u/l
0.20
198
1461
12
23
5.25
4.45
1.1
1.3
1.17
1.17
mmol/l
0.08
12
23
1003
10840
0.80
4.45
6.4
5.9
2.60
2.61
mmol/l
0.15
902
9908
19
65
2.95
4.44
1.2
1.1
—
—
—
0
0
19
65
2.95
4.44
1.2
1.1
—
—
—
0
0
1089
11655
0.79
4.40
34.9
22.9
82.89
83.34
umol/l
0.12
1081
11465
261
2025
1.35
4.40
5.1
3.1
0.81
0.82
mmol/l
1.16
243
1906
27
112
2.43
4.39
1.4
1.3
—
—
—
0
0
30
131
2.31
4.37
1.0
1.0
24.11
15.57
au/ml
—
7
33
32
144
2.25
4.35
1.6
1.4
—
—
—
0
0
32
145
2.23
4.29
1.6
1.4
—
—
—
0
0
32
145
2.23
4.29
1.6
1.4
—
—
—
0
0
378
3104
1.29
4.22
3.1
3.0
355.44
354.45
umol/l
0.06
327
2697
57
321
1.80
4.20
1.5
1.5
0.02
0.17
iu/ml
—
10
53
158
1138
1.43
4.17
2.1
3.0
65.83
66.32
g/l
0.32
146
1040
46
244
1.91
4.09
1.7
1.2
—
—
—
0
0
46
244
1.91
4.09
1.7
1.2
—
—
—
0
0
314
3845
0.77
4.08
4.5
4.7
22.87
22.11
%
0.35
155
1954
43
224
1.94
4.03
1.4
1.2
45.46
8.78
u/ml
—
5
12
591
5139
1.24
4.01
3.7
3.0
138.29
150.18
ug/l
0.51
532
4714
439
3694
1.26
3.98
3.7
3.2
34.06
36.11
u/l
0.32
411
3480
1073
11454
0.80
3.90
16.7
12.1
25.18
25.95
u/l
0.79
1047
11041
189
1423
1.37
3.86
9.7
7.5
1.70
0.64
mmol/l
3.37
153
1141
93
611
1.55
3.86
3.3
3.4
4.27
4.46
pmol/l
0.78
84
538
583
5081
1.23
3.83
2.9
2.4
78.69
78.76
nmol/l
0.02
527
4479
189
1433
1.36
3.70
9.8
7.5
5.30
4.99
kpa
3.66
180
1372
54
312
1.76
3.69
2.7
3.3
0.75
0.80
nmol/l
0.36
41
250
161
1191
1.39
3.67
2.7
2.2
0.20
0.20
g/l
0.38
145
1103
98
660
1.52
3.65
1.9
1.4
—
—
—
0
0
494
4249
1.24
3.64
3.2
3.4
2.35
2.35
mmol/l
0.10
450
3822
13
35
3.74
3.59
1.5
1.5
2.05
2.03
umol/l
0.02
13
30
188
1432
1.35
3.58
9.9
7.5
10.69
12.40
kpa
7.55
179
1373
299
2435
1.28
3.52
5.9
3.9
103.05
420.34
ng/l
5.60
212
2031
156
1158
1.38
3.49
3.3
2.4
7.84
7.41
ug/l
0.04
132
1004
69
435
1.61
3.44
1.3
1.2
—
—
—
0
0
65
404
1.63
3.43
1.9
1.7
7.36
8.54
iu/ml
0.13
14
103
697
6236
1.21
3.42
10.2
7.1
1.21
1.21
mmol/l
0.16
562
5300
991
10612
0.82
3.41
5.8
5.2
4.49
4.50
mmol/l
0.14
892
9749
22
96
2.31
3.27
1.3
1.4
—
—
—
0
0
74
482
1.56
3.23
1.7
3.9
49.84
73.20
mg/l
0.43
52
417
49
287
1.73
3.23
1.4
1.2
—
14.77
—
0
16
17
66
2.59
3.21
1.3
1.2
—
—
—
0
0
74
483
1.56
3.21
1.7
3.9
103.01
66.77
mg/l
0.22
52
416
468
4070
1.21
3.00
4.3
3.5
302.60
68.64
e6/l
0.45
385
3180
57
884
0.63
2.97
2.0
2.1
3.71
3.52
ratio
0.36
42
716
994
10587
0.84
2.96
6.0
5.3
6.07
6.04
mmol/l
0.31
894
9520
12
37
3.26
2.93
2.1
1.7
—
—
—
0
0
12
37
3.26
2.93
2.1
1.7
—
—
—
0
0
988
10516
0.84
2.86
5.7
5.1
1.41
1.43
mmol/l
1.25
885
9579
405
3492
1.21
2.82
4.1
3.4
0.52
0.46
e6/l
0.07
330
2643
22
103
2.15
2.81
1.7
1.4
12.18
14.24
u/l
1.35
22
97
272
2255
1.25
2.74
1.3
1.3
0.81
1.59
u/ml
1.99
73
605
165
1286
1.32
2.72
10.6
7.9
94.04
95.74
%
1.78
160
1243
15
60
2.51
2.70
1.3
1.1
28.10
31.78
u/l
—
10
50
947
10090
0.85
2.66
5.0
4.4
1.36
1.28
mmol/l
2.35
841
9098
293
2460
1.23
2.63
1.9
1.8
1139.61
1158.41
nmol/l
0.12
208
1844
45
276
1.65
2.57
1.5
1.2
1.58
2.64
u/ml
—
5
26
11
36
3.07
2.56
1.1
1.2
159.64
171.32
mmol/24h
0.14
11
36
16
68
2.37
2.56
2.1
1.6
13.80
5.58
u/l
—
10
55
1080
11367
0.84
2.55
31.9
21.0
3.99
4.00
mmol/l
0.95
1063
11091
422
4795
0.84
2.55
5.9
5.7
2.42
4.47
ug/l
1.40
369
4264
11
37
2.99
2.49
2.2
1.8
—
—
—
0
0
1079
11346
0.85
2.46
31.8
20.8
139.27
139.66
mmol/l
5.00
1064
11089
49
311
1.59
2.46
1.4
1.5
—
—
—
0
0
12
45
2.68
2.45
1.6
1.1
—
—
—
0
0
99
726
1.39
2.45
12.7
9.4
25.10
24.02
mmol/l
3.03
94
705
225
2709
0.80
2.44
5.2
4.3
1.02
1.02
kg/l
0.19
170
1835
40
639
0.62
2.42
1.8
1.9
3.69
3.50
mmol/l
0.39
27
472
25
131
1.92
2.41
1.2
1.3
273.61
278.97
mosm/kgh2o
0.43
18
96
5
8
6.26
2.37
2.2
1.9
23.10
26.63
mg/l
—
5
8
437
3858
1.18
2.30
2.8
2.2
191.34
228.08
u/l
0.56
411
3645
44
277
1.60
2.30
1.5
1.2
9.34
11.37
u/ml
—
7
47
18
86
2.11
2.23
1.5
1.1
—
—
—
0
0
9
29
3.11
2.22
1.3
1.0
—
—
—
0
0
173
1397
1.27
2.21
1.7
1.4
—
—
—
0
0
982
10355
0.86
2.12
7.7
6.7
40.63
39.92
mmol/mol
1.62
896
9555
16
75
2.14
2.08
1.1
1.1
95.94
104.47
pmol/l
0.24
16
75
45
293
1.55
2.07
1.6
1.4
32.58
29.57
iu/l
0.23
40
244
63
441
1.45
2.06
1.8
3.7
9.92
3.36
ratio
0.34
33
270
40
254
1.59
2.05
6.8
5.2
515.69
416.62
iu/ml
0.13
13
39
158
1275
1.27
2.04
6.5
3.3
2.34
1.54
mmol/l
2.23
140
1074
157
1266
1.27
2.04
3.6
2.6
68.86
66.78
e9/l
0.31
117
946
164
1330
1.26
2.03
2.3
2.8
7.52
9.90
umol/l
1.03
140
1189
945
8912
1.15
1.98
10.9
8.2
82.01
82.50
u/l
0.09
916
8388
343
3004
1.18
1.97
2.9
2.4
—
—
—
0
0
10
39
2.57
1.94
2.3
1.3
—
—
—
0
0
8
27
2.97
1.93
2.9
1.4
—
—
—
0
0
825
7716
1.14
1.93
6.3
5.0
5228.40
1949.93
e6/l
0.33
15
131
9
33
2.74
1.93
1.3
1.0
—
—
—
0
0
759
7064
1.14
1.90
4.3
3.3
55.63
54.58
u/l
0.11
706
6563
22
121
1.83
1.88
1.7
1.5
59.81
65.62
%
0.26
16
74
21
116
1.82
1.78
1.4
1.2
52.00
71.82
u/l
0.84
15
102
14
67
2.10
1.76
1.4
1.2
—
—
—
0
0
12
54
2.23
1.74
2.1
2.7
544.08
1551.94
u/ml
1.29
12
54
7
24
2.92
1.72
1.4
1.3
—
—
—
0
0
14
68
2.07
1.70
1.6
1.1
—
—
—
0
0
19
104
1.84
1.67
2.0
1.8
—
—
—
0
0
20
112
1.80
1.64
1.9
1.8
—
—
—
0
0
14
69
2.04
1.64
1.6
1.1
—
—
—
0
0
14
69
2.04
1.64
1.6
1.1
—
—
—
0
0
15
76
1.98
1.64
1.5
1.1
—
—
—
0
0
64
471
1.37
1.63
2.7
2.1
304.11
546.41
ug/l
1.11
59
448
15
77
1.96
1.59
3.7
1.9
138.33
120.29
ng/l
0.24
15
77
29
185
1.58
1.52
1.5
1.2
273.33
265.95
u/ml
0.05
15
104
6
21
2.86
1.50
1.3
1.0
—
—
—
0
0
45
319
1.42
1.45
2.6
2.4
3.87
3.59
g/l
0.55
39
307
47
336
1.41
1.44
1.7
1.6
24.89
20.03
u/ml
—
10
75
410
3721
1.14
1.44
1.9
1.7
18.93
20.07
nmol/l
0.95
355
3105
6
22
2.73
1.43
1.5
1.4
—
—
—
0
0
19
110
1.74
1.43
1.6
1.3
11.00
12.66
u/l
0.29
19
102
494
4545
1.13
1.40
5.1
4.2
0.02
0.05
estimate
1.39
175
1058
38
263
1.46
1.39
1.3
1.9
28.86
4.32
iu/l
0.45
15
96
871
8275
1.12
1.39
5.0
4.1
15.00
14.93
pmol/l
0.41
790
7442
16
89
1.81
1.37
1.0
1.0
—
—
—
0
0
155
1310
1.20
1.36
6.6
3.3
6.00
5.70
kpa
3.57
150
1273
17
285
0.59
1.35
1.0
1.2
1.35
1.53
g/l
1.89
17
285
81
638
1.28
1.35
1.4
1.3
31.76
63.06
au/ml
—
5
46
74
576
1.30
1.34
1.8
2.7
4.26
4.17
g/l
0.40
69
521
13
68
1.92
1.33
1.5
1.1
—
—
—
0
0
22
137
1.61
1.29
2.3
2.5
11.20
21.12
mg/l
—
10
51
22
137
1.61
1.29
1.2
1.1
—
—
—
0
0
39
278
1.41
1.25
1.4
1.3
—
—
—
0
0
13
70
1.86
1.24
1.5
3.8
115.23
109.71
nmol/l
0.04
13
70
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
59
456
1.30
1.16
4.5
2.7
0.38
0.34
iu/ml
0.41
40
250
16
260
0.61
1.16
1.4
1.5
—
—
—
0
0
5
20
2.50
1.15
1.2
1.0
53.42
42.44
u/ml
—
5
20
160
1383
1.17
1.12
3.8
4.2
6.41
21.96
ug/l
1.61
130
1130
196
1722
1.16
1.12
9.4
5.5
1.03
1.03
mmol/l
0.08
182
1584
23
151
1.53
1.11
1.5
1.4
6.13
6.53
mmol/l
0.42
23
143
43
320
1.35
1.10
1.3
1.3
—
—
—
0
0
5
21
2.38
1.09
1.0
1.0
21.68
48.60
iu/ml
—
5
21
14
81
1.73
1.09
1.4
1.2
—
—
—
0
0
73
587
1.26
1.07
1.9
1.8
—
—
—
0
0
137
1176
1.18
1.06
10.9
6.9
1.43
1.39
mmol/l
0.14
132
1149
649
6136
1.10
1.05
5.0
4.1
0.03
0.25
estimate
0.44
183
1239
41
306
1.35
1.04
2.0
2.2
—
—
—
0
0
972
10060
0.91
1.03
6.4
5.1
1.89
2.01
mu/l
2.17
907
9125
32
231
1.39
0.99
1.5
1.7
236.50
281.61
mu/l
0.62
26
209
40
300
1.34
0.99
1.6
1.6
10662.13
13584.78
e6/l
0.38
30
205
189
2126
0.87
0.99
4.0
3.1
1.13
1.13
e6/l
0.01
108
1172
5
23
2.18
0.98
1.2
1.1
—
—
—
0
0
24
165
1.46
0.97
1.5
1.4
82200.14
80355.90
e6/l
0.01
14
88
589
5564
1.09
0.96
2.3
2.2
96.07
94.35
pmol/l
0.34
323
2977
372
3438
1.11
0.96
5.2
4.2
0.00
0.01
estimate
0.96
181
1131
21
142
1.48
0.92
1.4
1.3
6.90
6.06
u/ml
—
10
48
86
719
1.21
0.91
2.6
2.5
12.47
20.76
au/ml
1.27
11
59
1015
10457
0.92
0.90
27.5
17.1
77.49
75.40
ml/min/173m2
2.47
971
9752
51
404
1.27
0.88
1.7
1.7
0.40
0.35
mg/l
0.30
25
197
124
1075
1.17
0.88
2.0
1.8
1.52
1.50
%
0.10
104
930
13
79
1.65
0.88
1.5
1.2
—
85.00
—
0
6
8
43
1.86
0.87
1.6
1.3
9.38
10.53
mm/h
—
8
43
6
30
2.00
0.87
1.0
1.0
—
—
—
0
0
8
44
1.82
0.86
1.8
1.1
1.10
1.06
ratio
—
8
35
78
651
1.21
0.85
2.1
1.8
—
—
—
0
0
411
4389
0.91
0.85
2.1
1.9
1.42
1.32
mmol/l
1.00
307
3633
282
2587
1.11
0.84
3.1
3.0
2.48
2.46
mmol/l
2.13
252
2319
43
337
1.28
0.82
5.0
3.5
1.00
2.04
index
1.11
24
185
34
258
1.32
0.81
1.9
2.1
—
—
—
0
0
12
73
1.65
0.81
1.6
2.5
7.47
8.93
mmol/l
0.81
12
73
13
81
1.61
0.81
2.5
1.5
1.39
0.77
promille
—
7
63
8
47
1.71
0.80
1.1
1.2
—
—
—
0
0
14
212
0.66
0.80
1.4
1.5
—
—
—
0
0
30
224
1.35
0.80
1.5
1.4
10.67
9.72
u/l
0.13
22
170
178
1977
0.89
0.79
4.1
3.2
2.83
1.89
e6/l
0.78
99
1028
27
199
1.36
0.78
1.6
1.3
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
1.08
—
0
20
6
34
1.77
0.76
1.8
2.3
4.65
4.61
kpa
—
6
34
6
34
1.77
0.76
1.8
2.3
9.80
10.32
kpa
—
6
34
10
59
1.70
0.75
1.6
1.3
—
—
—
0
0
10
59
1.70
0.75
1.6
1.3
—
—
—
0
0
586
5584
1.08
0.75
8.4
6.4
1.21
1.21
mmol/l
0.01
540
5114
13
83
1.57
0.75
1.5
1.3
—
—
—
0
0
13
83
1.57
0.75
1.5
1.3
—
—
—
0
0
26
193
1.35
0.73
2.2
1.4
140.50
162.48
au/ml
—
6
57
638
6106
1.07
0.72
5.0
4.1
0.00
4.92
estimate
1.33
199
1321
1064
10891
0.93
0.70
30.5
17.0
24.44
27.45
mg/l
2.41
985
9030
30
231
1.30
0.68
1.1
1.3
277.25
232.03
miu/ml
—
8
94
627
6020
1.07
0.64
5.0
4.1
0.00
0.00
estimate
0.50
198
1289
5
29
1.73
0.64
1.0
1.1
97.60
103.41
%
—
5
22
16
112
1.43
0.63
1.8
1.5
20.13
34.36
ng/l
0.74
16
112
24
182
1.32
0.61
1.7
1.4
2074.58
1250.36
e6/l
0.56
19
118
8
50
1.60
0.61
1.4
1.9
39.09
40.53
g/l
—
8
50
8
52
1.54
0.59
1.8
1.4
25.79
29.52
umol/l
—
8
47
36
294
1.23
0.54
2.9
2.5
203.71
198.83
%
0.10
31
282
53
451
1.18
0.53
1.1
1.1
—
—
—
0
0
15
108
1.39
0.53
5.9
3.8
10.00
11.48
index
—
10
67
6
39
1.54
0.53
1.0
1.8
9.73
6.28
nmol/l
—
6
32
15
109
1.38
0.51
1.5
2.0
3.75
4.72
mg/l
0.59
15
104
13
92
1.42
0.50
4.1
2.5
871.43
684.53
ml
—
7
58
20
153
1.31
0.50
3.6
1.9
13817.31
6300.50
u/l
—
8
57
43
362
1.19
0.49
1.3
1.5
—
—
—
0
0
92
822
1.13
0.49
2.0
1.6
—
—
—
0
0
7
45
1.56
0.49
2.6
3.0
0.60
0.60
mmol/l
—
7
45
7
48
1.46
0.46
1.1
1.0
1002.86
219.29
iu/ml
—
7
48
425
4078
1.06
0.44
4.8
4.1
9.60
8.91
mg/mmol
0.12
268
2580
34
285
1.20
0.42
3.6
2.4
42.42
89.13
ug/min
1.03
17
171
6
92
0.65
0.42
1.2
1.1
—
—
—
0
0
43
499
0.86
0.42
3.7
3.2
16.73
7953.54
u/ml
0.83
34
432
428
4114
1.05
0.42
3.8
3.4
7.25
7.43
mmol/l
0.33
353
3406
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
560
5425
1.05
0.40
3.3
2.9
—
—
estimate
—
0
0
68
607
1.13
0.39
1.2
1.2
57.81
133.99
u/ml
2.26
21
227
22
181
1.22
0.34
1.5
1.9
4.28
4.72
mmol/24h
0.28
22
160
121
1124
1.08
0.34
2.4
2.5
32.21
41.56
u/l
1.25
101
933
6
44
1.36
0.34
1.0
1.2
5.69
6.17
mmol/l
—
6
44
39
443
0.88
0.31
1.3
1.3
—
—
—
0
0
21
251
0.83
0.31
1.4
1.4
2433.00
518.37
e6/l
0.36
16
205
92
992
0.92
0.29
2.4
2.3
12.43
12.59
nmol/l
0.06
86
880
56
506
1.11
0.29
2.0
2.8
10.24
10.88
g/l
0.48
51
448
15
121
1.24
0.28
2.7
2.9
—
—
—
0
0
10
76
1.32
0.28
1.4
1.3
—
—
—
0
0
10
76
1.32
0.28
1.4
1.3
—
—
—
0
0
21
247
0.85
0.27
1.2
1.4
9.43
65.19
e6/l
0.97
14
191
103
964
1.07
0.26
5.4
3.7
106.49
94.85
ng/l
0.68
87
823
5
73
0.68
0.26
1.2
1.8
328.60
314.30
mu/l
—
5
53
9
75
1.20
0.25
1.3
2.4
—
—
—
0
0
11
87
1.27
0.24
3.9
2.6
13.35
13.21
%
0.18
11
87
53
486
1.09
0.23
2.4
2.8
1.93
1.60
g/l
0.17
47
416
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
6.17
—
0
10
0
11
0.00
0.21
0.0
5.3
—
—
—
0
0
8
103
0.78
0.21
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
3.0
—
65.65
—
0
14
6
48
1.25
0.20
1.7
1.4
98.45
52.48
ug/l
—
6
48
7
61
1.15
0.17
1.0
1.3
—
—
—
0
0
18
157
1.15
0.17
1.9
1.4
—
—
—
0
0
198
1919
1.04
0.16
2.5
2.0
30.49
29.71
s
0.88
187
1865
8
70
1.14
0.16
3.8
1.5
—
—
—
0
0
308
3016
1.03
0.14
4.8
4.1
86.44
85.11
%
0.38
292
2951
70
665
1.05
0.14
1.6
1.7
1.60
1.56
g/l
0.15
63
572
16
142
1.13
0.12
1.1
1.2
5.20
6.16
u/ml
—
5
69
34
365
0.93
0.12
2.4
2.8
0.00
0.00
g/l
-0.00
34
339
25
272
0.92
0.12
5.6
3.6
20.13
29.21
mg/l
1.31
15
203
28
302
0.93
0.11
1.0
1.1
—
—
—
0
0
16
145
1.10
0.09
1.1
1.0
—
—
—
0
0
16
175
0.91
0.08
1.1
1.1
39.20
32.45
iu/ml
—
5
26
19
175
1.09
0.08
1.1
1.1
—
1.20
—
0
6
7
64
1.09
0.08
1.0
1.0
—
—
—
0
0
6
75
0.80
0.07
1.2
2.1
—
106.12
—
0
17
6
75
0.80
0.07
2.0
2.6
—
—
—
0
0
9
87
1.03
0.07
1.6
1.6
34.11
58.00
ug/l
—
9
73
9
101
0.89
0.06
1.6
1.2
—
—
—
0
0
29
304
0.95
0.06
1.0
1.1
—
—
—
0
0
118
1200
0.98
0.05
1.4
1.5
—
—
—
0
0
144
1461
0.98
0.05
5.2
5.0
32.87
32.90
%
0.01
100
919
80
817
0.98
0.05
6.5
2.8
129.47
126.42
g/l
0.60
74
796
27
258
1.05
0.04
2.0
1.6
—
—
—
0
0
28
268
1.05
0.04
1.5
1.3
—
—
—
0
0
14
130
1.08
0.04
2.1
2.0
1.43
1.36
u/field
—
7
69
89
898
0.99
0.01
3.0
3.0
61.37
62.92
ml/min/173m2
0.12
38
419
11
114
0.96
0.00
1.2
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.5
1.7
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.0
2365.80
1624.67
miu/ml
—
5
49
0
5
0.00
-0.00
0.0
1.2
—
38.28
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
2.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
57.86
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
8.18
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
21.32
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint J10_BRONCHNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_BRONCHNAS | 1.856 [1.65, 2.08] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.249 |
During the follow-up period (1.1.1998 — 31.12.2019), 1058 out of 2991 females with J10_BRONCHNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_BRONCHNAS | 2.101 [1.86, 2.37] | < 0.001 |
| Birth year | 0.986 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 1766 out of 3561 males with J10_BRONCHNAS died.
Mortality risk
Mortality risk for people of age
years, who have J10_BRONCHNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.175% | 0.429% |
| 5 | 0.997% | 2.609% |
| 10 | 2.501% | 6.064% |
| 15 | 5.092% | 10.933% |
| 20 | 8.903% | 18.446% |
Relationships between endpoints
↥Index endpoint: J10_BRONCHNAS – Unspecified chronic bronchitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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